4IRVA

Structure of the helicobacter pylori caga oncogene bound to the human tumor suppressor apoptosis-stimulating protein of p53-2
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
198
structure length
197
Chain Sequence
QQFINNLQVAFIKVDNVVASFDPDQKPIVDKNDRDNRQAFDGISQLREEYSNKAIKNPTKKNQYFSDFIDKSNDLINKDNLIDVESSTKSFQKFGDQRYQIFTSWVSHQKDPSKINTRSIRNFMENIIQPPIPDDKEKAEFLKSAKQSFAGIIIGNQIRTDQKFMGVFDESLKERQEAEKGGPTGGDWLDIFLSFIF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Cytotoxicity-associated immunodominant antigen
publication title Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.
pubmed doi rcsb
source organism Helicobacter pylori
molecule tags Protein binding
total genus 76
structure length 197
sequence length 198
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.357.130 Mainly Alpha Orthogonal Bundle Tetracycline Repressor; domain 2 Tetracycline Repressor; domain 2 4irvA00
4IRVA 4DVYP
chains in the Genus database with same CATH superfamily
2OI8A 2ZB9A 2WV1A 5FGLA 3LWJA 2ZY9A 2VKEA 3WHBA 3LSPA 2G0EA 3FK6A 2D6YA 5K7HA 3BT9A 2OF7A 3T6NA 3Q3SA 4M3DA 3KZ9A 2REKA 3FHNA 3O8GA 2RAEA 2Y2ZA 3PASA 3C2BA 4M3BA 3G1OA 3BJBA 5GPCA 5D18A 2DTZA 2FD5A 3IUVA 3BR2A 4ABZA 5DAJA 3LHQA 3LOCA 5GPAA 1Z0XA 4OD4A 3HE0A 4C2MA 4MXMA 1ORKA 3NXCA 3PPBA 4W1UA 4X1EA 3MNLA 4ICHA 5EYRA 2Y30A 5F04A 5FKNA 2XB5A 3AQTA 3EGQA 3EUPA 3IH3A 3VW0A 3FRQA 4GCKA 3HGGA 1UI5A 5GP9A 3Q0VA 3VW2A 3B6AA 2RHAA 3BTLA 2TRTA 2IU5A 2HYTA 2FQ4A 5FKOA 3HTHA 5IPAA 3ON4A 3BTJA 2GENA 2PFVA 3FK7A 3KKDA 3VP5A 2DG7A 3P9TA 2G7GA 3RH2A 4D5FA 3VOXA 4DW6A 3VVZA 2QTQA 5D1RA 2R7VA 4NELA 5D19A 2R7WA 3FIWA 3IH2A 2WGBA 1VI0A 1RKWA 4AF5A 2UXIA 2QOPA 2O7OA 3QQAA 5J3LA 4V2FA 5IOYA 4GCLA 4ME9A 3VW1A 5AQCA 5J1RA 5F1JA 2VKVA 2QKOA 5IP6A 2GFNA 2UXUA 3F1BA 3B81A 2B1EA 2ZCMA 3BNIA 1QVUA 2F07A 2JK3A 2IEKA 4D7NA 3C07A 3TP0A 2WUIA 3ZQFA 4GFKA 4M3FA 2ID6A 4GFLA 1BJZA 4JKZA 1ZKGA 2R7SA 3F0CA 3O8HA 5J1UA 3BR5A 1UI6A 5CXIA 2ZCNA 3VVYA 5FKKA 5CW8A 1ZK8A 4B1RA 4B3AA 2RASA 2XPVA 3WHCA 4I76A 4L62A 3HTAA 3O60A 3ZQIA 2O7TA 2XDNA 3V6GA 2HQ5A 3NNRA 4D7MA 2R7XA 4KWAA 3QPSA 1JUSA 4WIBA 1SGMA 4D5CA 2I10A 2EH3A 2UXHA 3BR0A 3CRJA 4I6ZA 2X9DA 3JSJA 2FJ1A 1JTXA 3BQZA 2HXIA 3V78A 2OERA 2VPRA 4W97A 4AC6A 2IAIA 4UDSA 5K7FA 3SDGA 3ON2A 3ANPA 2R7UA 2ZOZA 2ID3A 3K8PC 2NX4A 2YVHA 5HAWA 5EZHA 3BR1A 2R7RA 2ZCXA 2G7SA 2ZOYA 2R7TA 4AC0A 1JT6A 2G7LA 3ZQLA 5FHPA 2GUHA 3AQSA 5FMPA 5EZGA 2G3BA 5F0CA 2XRLA 2Q24A 2XPWA 3ANGA 3E7QA 3SFIA 2V57A 3NPIA 3VVXA 3Q0UA 2OPTA 2R7OA 3G1MA 5HSZA 3BTIA 2UXOA 3VPRA 3VTIA 5IOZA 3BR3A 3G56A 2HYJA 3LSRA 5K58A 3G7RA 5J1YA 2UXPA 3GZIA 5F0HA 2DG8A 1JT0A 4XK4A 2GBYA 3KKCA 3TP3A 4MO7A 2B3WA 3HTIA 2HXOA 3BTCA 3BR6A 5FKMA 3DU5A 5F0FA 5F27A 3BQYA 2NP3A 3CDLA 3NI7A 3QKXA 5FKLA 2TCTA 1T56A 2FJI1 2YVEA 3ZQHA 1JUPA 5CQGA 3CJDA 3ZQGA 2JJ7A 3KNWA 2XGEA 4ACIA 1U9OA 4YZEA 3VUQA 1RKTA 2FBQA 3HGYA 4JYKA 3PM1A 4DVYP 3QPLA 3VOKA 3DPJA 2QIBA 3IH4A 4CGRA 2XGCA 2X6OA 5F08A 3RD3A 5K7ZA 3DCFA 2XPUA 3BCGA 2YVXA 4G12A 2XGDA 2R7QA 3COLA 4M3GA 3BHQA 3LJLA 3B6CA 2QCOA 1QVTA 4NN1A 3GEUA 2FX0A 1Z77A 2IBDA 2PBXA 4U9LA 4U9NA 3DU6A 3VIBA 3G1LA 3KYLA 3HTJA 2PZ9A 4OD5A 4HKUA 5EFYA 5HBUA 2QWTA 4M3EA 1U9NA 1JTYA 1A6IA 5C4YA 4GCTA 2NS8A 3NRGA 4JL3A 2NS7A 4IRVA 3S5RA 2HKUA 2NP5A 3LSJA 1QPIA 4AUXA 5CXGA 3CWRA 3CCYA 3HIMA 4V2GA 4PXIA 3Q0WA 2W53A 4JNNA 1T33A 3BRUA 3DEWA 3SWHA 2A2FX 1JUMA 3MVPA 3NS4A 4MK6A 5H9TA 3QBMA 2Y31A 1RPWA
chains in the Genus database with same CATH topology
3K8PC 4OD4A 3FHNA 3KYLA 4C2MA 2PFVA 4DVYP 4OD5A 2R7RA 2FJI1 3SWHA 2A2FX 3NS4A 5CQGA 2R7SA 2B3WA 2R7TA 2R7QA 2R7OA 2R7XA 4IRVA 2R7UA 2R7VA 2B1EA 3DU5A 2R7WA 3VTIA 3DU6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IRV A;  4DVY P; 
#chains in the Genus database with same CATH topology
 2OI8 A;  2ZB9 A;  2WV1 A;  5FGL A;  3LWJ A;  2ZY9 A;  2VKE A;  3WHB A;  3LSP A;  2G0E A;  3FK6 A;  2D6Y A;  5K7H A;  3BT9 A;  2OF7 A;  3T6N A;  3Q3S A;  4M3D A;  3KZ9 A;  2REK A;  3FHN A;  3O8G A;  2RAE A;  2Y2Z A;  3PAS A;  3C2B A;  4M3B A;  3G1O A;  3BJB A;  5GPC A;  5D18 A;  2DTZ A;  2FD5 A;  3IUV A;  3BR2 A;  4ABZ A;  5DAJ A;  3LHQ A;  3LOC A;  5GPA A;  1Z0X A;  4OD4 A;  3HE0 A;  4C2M A;  4MXM A;  1ORK A;  3NXC A;  3PPB A;  4W1U A;  4X1E A;  3MNL A;  4ICH A;  5EYR A;  2Y30 A;  5F04 A;  5FKN A;  2XB5 A;  3AQT A;  3EGQ A;  3EUP A;  3IH3 A;  3VW0 A;  3FRQ A;  4GCK A;  3HGG A;  1UI5 A;  5GP9 A;  3Q0V A;  3VW2 A;  3B6A A;  2RHA A;  3BTL A;  2TRT A;  2IU5 A;  2HYT A;  2FQ4 A;  5FKO A;  3HTH A;  5IPA A;  3ON4 A;  3BTJ A;  2GEN A;  2PFV A;  3FK7 A;  3KKD A;  3VP5 A;  2DG7 A;  3P9T A;  2G7G A;  3RH2 A;  4D5F A;  3VOX A;  4DW6 A;  3VVZ A;  2QTQ A;  5D1R A;  2R7V A;  4NEL A;  5D19 A;  2R7W A;  3FIW A;  3IH2 A;  2WGB A;  1VI0 A;  1RKW A;  4AF5 A;  2UXI A;  2QOP A;  2O7O A;  3QQA A;  5J3L A;  4V2F A;  5IOY A;  4GCL A;  4ME9 A;  3VW1 A;  5AQC A;  5J1R A;  5F1J A;  2VKV A;  2QKO A;  5IP6 A;  2GFN A;  2UXU A;  3F1B A;  3B81 A;  2B1E A;  2ZCM A;  3BNI A;  1QVU A;  2F07 A;  2JK3 A;  2IEK A;  4D7N A;  3C07 A;  3TP0 A;  2WUI A;  3ZQF A;  4GFK A;  4M3F A;  2ID6 A;  4GFL A;  1BJZ A;  4JKZ A;  1ZKG A;  2R7S A;  3F0C A;  3O8H A;  5J1U A;  3BR5 A;  1UI6 A;  5CXI A;  2ZCN A;  3VVY A;  5FKK A;  5CW8 A;  1ZK8 A;  4B1R A;  4B3A A;  2RAS A;  2XPV A;  3WHC A;  4I76 A;  4L62 A;  3HTA A;  3O60 A;  3ZQI A;  2O7T A;  2XDN A;  3V6G A;  2HQ5 A;  3NNR A;  4D7M A;  2R7X A;  4KWA A;  3QPS A;  1JUS A;  4WIB A;  1SGM A;  4D5C A;  2I10 A;  2EH3 A;  2UXH A;  3BR0 A;  3CRJ A;  4I6Z A;  2X9D A;  3JSJ A;  2FJ1 A;  1JTX A;  3BQZ A;  2HXI A;  3V78 A;  2OER A;  2VPR A;  4W97 A;  4AC6 A;  2IAI A;  4UDS A;  5K7F A;  3SDG A;  3ON2 A;  3ANP A;  2R7U A;  2ZOZ A;  2ID3 A;  3K8P C;  2NX4 A;  2YVH A;  5HAW A;  5EZH A;  3BR1 A;  2R7R A;  2ZCX A;  2G7S A;  2ZOY A;  2R7T A;  4AC0 A;  1JT6 A;  2G7L A;  3ZQL A;  5FHP A;  2GUH A;  3AQS A;  5FMP A;  5EZG A;  2G3B A;  5F0C A;  2XRL A;  2Q24 A;  2XPW A;  3ANG A;  3E7Q A;  3SFI A;  2V57 A;  3NPI A;  3VVX A;  3Q0U A;  2OPT A;  2R7O A;  3G1M A;  5HSZ A;  3BTI A;  2UXO A;  3VPR A;  3VTI A;  5IOZ A;  3BR3 A;  3G56 A;  2HYJ A;  3LSR A;  5K58 A;  3G7R A;  5J1Y A;  2UXP A;  3GZI A;  5F0H A;  2DG8 A;  1JT0 A;  4XK4 A;  2GBY A;  3KKC A;  3TP3 A;  4MO7 A;  2B3W A;  3HTI A;  2HXO A;  3BTC A;  3BR6 A;  5FKM A;  3DU5 A;  5F0F A;  5F27 A;  3BQY A;  2NP3 A;  3CDL A;  3NI7 A;  3QKX A;  5FKL A;  2TCT A;  1T56 A;  2FJI 1;  2YVE A;  3ZQH A;  1JUP A;  5CQG A;  3CJD A;  3ZQG A;  2JJ7 A;  3KNW A;  2XGE A;  4ACI A;  1U9O A;  4YZE A;  3VUQ A;  1RKT A;  2FBQ A;  3HGY A;  4JYK A;  3PM1 A;  4DVY P;  3QPL A;  3VOK A;  3DPJ A;  2QIB A;  3IH4 A;  4CGR A;  2XGC A;  2X6O A;  5F08 A;  3RD3 A;  5K7Z A;  3DCF A;  2XPU A;  3BCG A;  2YVX A;  4G12 A;  2XGD A;  2R7Q A;  3COL A;  4M3G A;  3BHQ A;  3LJL A;  3B6C A;  2QCO A;  1QVT A;  4NN1 A;  3GEU A;  2FX0 A;  1Z77 A;  2IBD A;  2PBX A;  4U9L A;  4U9N A;  3DU6 A;  3VIB A;  3G1L A;  3KYL A;  3HTJ A;  2PZ9 A;  4OD5 A;  4HKU A;  5EFY A;  5HBU A;  2QWT A;  4M3E A;  1U9N A;  1JTY A;  1A6I A;  5C4Y A;  4GCT A;  2NS8 A;  3NRG A;  4JL3 A;  2NS7 A;  4IRV A;  3S5R A;  2HKU A;  2NP5 A;  3LSJ A;  1QPI A;  4AUX A;  5CXG A;  3CWR A;  3CCY A;  3HIM A;  4V2G A;  4PXI A;  3Q0W A;  2W53 A;  4JNN A;  1T33 A;  3BRU A;  3DEW A;  3SWH A;  2A2F X;  1JUM A;  3MVP A;  3NS4 A;  4MK6 A;  5H9T A;  3QBM A;  2Y31 A;  1RPW A; 
#chains in the Genus database with same CATH homology
 3K8P C;  4OD4 A;  3FHN A;  3KYL A;  4C2M A;  2PFV A;  4DVY P;  4OD5 A;  2R7R A;  2FJI 1;  3SWH A;  2A2F X;  3NS4 A;  5CQG A;  2R7S A;  2B3W A;  2R7T A;  2R7Q A;  2R7O A;  2R7X A;  4IRV A;  2R7U A;  2R7V A;  2B1E A;  3DU5 A;  2R7W A;  3VTI A;  3DU6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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