4IRVA

Structure of the helicobacter pylori caga oncogene bound to the human tumor suppressor apoptosis-stimulating protein of p53-2
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
198
structure length
197
Chain Sequence
QQFINNLQVAFIKVDNVVASFDPDQKPIVDKNDRDNRQAFDGISQLREEYSNKAIKNPTKKNQYFSDFIDKSNDLINKDNLIDVESSTKSFQKFGDQRYQIFTSWVSHQKDPSKINTRSIRNFMENIIQPPIPDDKEKAEFLKSAKQSFAGIIIGNQIRTDQKFMGVFDESLKERQEAEKGGPTGGDWLDIFLSFIF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.
pubmed doi rcsb
source organism Helicobacter pylori
molecule tags Protein binding
molecule keywords Cytotoxicity-associated immunodominant antigen
total genus 76
structure length 197
sequence length 198
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.357.130 Mainly Alpha Orthogonal Bundle Tetracycline Repressor; domain 2 Tetracycline Repressor; domain 2 4irvA00
4DVYP 4IRVA
chains in the Genus database with same CATH superfamily
3BHQA 1RKTA 4MXMA 3Q0VA 1VI0A 3BCGA 3DU5A 4GFKA 2XPWA 5FKNA 3TP3A 2OF7A 1JTYA 3SDGA 2YVEA 3BR5A 4D5CA 5IOYA 2UXUA 3VVXA 5FKOA 5EZGA 3AQSA 2Y2ZA 4C2MA 4JYKA 5J1UA 2TRTA 3BRUA 2V57A 3VVYA 2Q24A 4JNNA 3KNWA 4G12A 3WHCA 3T6NA 2O7OA 4M3EA 3RD3A 1Z0XA 3FK6A 3FIWA 3VOKA 4M3DA 3HIMA 2VPRA 3EGQA 2NP5A 3IH2A 4NELA 2HYTA 1T56A 3B6AA 3GEUA 3G7RA 5F04A 2WV1A 2B3WA 5F27A 2O7TA 3KKDA 3BNIA 3FRQA 3ZQHA 2UXOA 4D7MA 4CGRA 2QWTA 2B1EA 5K7ZA 1JT0A 3VVZA 5FGLA 5FKLA 3B81A 4V2GA 2HKUA 2GENA 3SWHA 3VPRA 1QPIA 5HSZA 3BR0A 3CRJA 4WIBA 2XDNA 5CQGA 5D19A 2XGEA 4W1UA 1Z77A 2VKVA 2GUHA 3G1OA 3AQTA 3HTAA 4AUXA 4B1RA 5H9TA 3BQYA 3HGYA 1UI5A 4DVYP 2ZB9A 3B6CA 3BT9A 2FBQA 4M3BA 3O8HA 1RKWA 5J1RA 1U9OA 2NS7A 4ABZA 3QPLA 3QQAA 2IBDA 3BTLA 5J1YA 3G56A 2ZCXA 5K58A 1RPWA 3LWJA 2ID3A 2VKEA 1BJZA 5EZHA 4OD4A 4M3GA 4JL3A 5EFYA 4NN1A 2ZOYA 5HBUA 2REKA 4GFLA 2OI8A 2D6YA 3NRGA 4GCLA 1ORKA 3VP5A 2RASA 4U9NA 4ICHA 5FHPA 4MO7A 2IU5A 2PBXA 5D1RA 2HXOA 3FK7A 3KYLA 3VIBA 2ZOZA 4YZEA 5K7FA 3COLA 3ON2A 2G7GA 3TP0A 4I6ZA 4L62A 3HTHA 2I10A 2NX4A 5K7HA 2F07A 2X9DA 4I76A 2R7XA 4B3AA 3ANGA 3Q3SA 4OD5A 4UDSA 5J3LA 2QIBA 2Y31A 3ON4A 3BJBA 3CCYA 3SFIA 2GBYA 2QTQA 2Y30A 3EUPA 5F08A 3CJDA 3ANPA 2R7QA 2FX0A 2HYJA 1ZK8A 4GCKA 3JSJA 3HE0A 3CDLA 5CW8A 3F1BA 2UXIA 4IRVA 5CXIA 2R7UA 3PPBA 3GZIA 4XK4A 4ME9A 1JUMA 3ZQFA 2XGCA 3BR6A 3PASA 3BR1A 2DTZA 3RH2A 3BTCA 3IUVA 4JKZA 1QVUA 3VW0A 2R7RA 2ID6A 3Q0WA 3LSRA 2OPTA 1SGMA 2FD5A 1JUSA 3DU6A 3V6GA 3VTIA 3NS4A 2TCTA 3K8PC 3BR2A 3BR3A 2HQ5A 3LOCA 3KZ9A 5EYRA 2RAEA 2ZCNA 1ZKGA 3CWRA 5HAWA 3O60A 5CXGA 3G1LA 5DAJA 4U9LA 3HGGA 2G3BA 5F1JA 2R7WA 5F0HA 4PXIA 3ZQLA 3LJLA 2QCOA 5IOZA 3LHQA 2R7TA 2G7LA 4X1EA 2WGBA 4V2FA 3NI7A 5FMPA 4AF5A 3PM1A 3HTJA 2WUIA 2IAIA 2R7OA 2W53A 2NP3A 3O8GA 2X6OA 3VW2A 2YVHA 3DPJA 4HKUA 3MVPA 1QVTA 5IPAA 2QKOA 1U9NA 4AC0A 3ZQGA 4DW6A 3DCFA 2UXHA 5C4YA 2RHAA 3Q0UA 5GP9A 3VOXA 3E7QA 2ZY9A 1JTXA 3DEWA 3F0CA 2DG7A 2UXPA 4ACIA 2G0EA 5F0FA 2EH3A 1JT6A 2HXIA 3S5RA 2OERA 1UI6A 5GPAA 2R7VA 5D18A 2GFNA 3C07A 3LSPA 3MNLA 5AQCA 3G1MA 3IH4A 5GPCA 2JJ7A 3LSJA 3IH3A 2PFVA 2R7SA 1T33A 2FJ1A 2ZCMA 4AC6A 2JK3A 2A2FX 2NS8A 2XPVA 4W97A 2XB5A 3NXCA 4MK6A 2XGDA 2XRLA 2XPUA 4D7NA 3QKXA 2YVXA 4M3FA 3VW1A 3BQZA 1JUPA 3VUQA 2QOPA 2IEKA 4KWAA 1A6IA 3NPIA 3P9TA 3V78A 4D5FA 3QPSA 3BTIA 3QBMA 3ZQIA 3KKCA 5IP6A 5FKMA 4GCTA 3BTJA 2DG8A 2G7SA 3NNRA 2PZ9A 3FHNA 5F0CA 3C2BA 5FKKA 3WHBA 3HTIA 2FJI1 2FQ4A
chains in the Genus database with same CATH topology
4IRVA 2R7VA 2R7XA 4OD5A 2R7UA 4DVYP 2B3WA 2R7OA 4OD4A 3DU5A 2R7WA 3KYLA 3VTIA 3DU6A 3NS4A 3K8PC 5CQGA 2B1EA 2PFVA 2R7QA 2R7TA 2R7SA 3FHNA 2R7RA 2FJI1 3SWHA 4C2MA 2A2FX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DVY P;  4IRV A; 
#chains in the Genus database with same CATH topology
 3BHQ A;  1RKT A;  4MXM A;  3Q0V A;  1VI0 A;  3BCG A;  3DU5 A;  4GFK A;  2XPW A;  5FKN A;  3TP3 A;  2OF7 A;  1JTY A;  3SDG A;  2YVE A;  3BR5 A;  4D5C A;  5IOY A;  2UXU A;  3VVX A;  5FKO A;  5EZG A;  3AQS A;  2Y2Z A;  4C2M A;  4JYK A;  5J1U A;  2TRT A;  3BRU A;  2V57 A;  3VVY A;  2Q24 A;  4JNN A;  3KNW A;  4G12 A;  3WHC A;  3T6N A;  2O7O A;  4M3E A;  3RD3 A;  1Z0X A;  3FK6 A;  3FIW A;  3VOK A;  4M3D A;  3HIM A;  2VPR A;  3EGQ A;  2NP5 A;  3IH2 A;  4NEL A;  2HYT A;  1T56 A;  3B6A A;  3GEU A;  3G7R A;  5F04 A;  2WV1 A;  2B3W A;  5F27 A;  2O7T A;  3KKD A;  3BNI A;  3FRQ A;  3ZQH A;  2UXO A;  4D7M A;  4CGR A;  2QWT A;  2B1E A;  5K7Z A;  1JT0 A;  3VVZ A;  5FGL A;  5FKL A;  3B81 A;  4V2G A;  2HKU A;  2GEN A;  3SWH A;  3VPR A;  1QPI A;  5HSZ A;  3BR0 A;  3CRJ A;  4WIB A;  2XDN A;  5CQG A;  5D19 A;  2XGE A;  4W1U A;  1Z77 A;  2VKV A;  2GUH A;  3G1O A;  3AQT A;  3HTA A;  4AUX A;  4B1R A;  5H9T A;  3BQY A;  3HGY A;  1UI5 A;  4DVY P;  2ZB9 A;  3B6C A;  3BT9 A;  2FBQ A;  4M3B A;  3O8H A;  1RKW A;  5J1R A;  1U9O A;  2NS7 A;  4ABZ A;  3QPL A;  3QQA A;  2IBD A;  3BTL A;  5J1Y A;  3G56 A;  2ZCX A;  5K58 A;  1RPW A;  3LWJ A;  2ID3 A;  2VKE A;  1BJZ A;  5EZH A;  4OD4 A;  4M3G A;  4JL3 A;  5EFY A;  4NN1 A;  2ZOY A;  5HBU A;  2REK A;  4GFL A;  2OI8 A;  2D6Y A;  3NRG A;  4GCL A;  1ORK A;  3VP5 A;  2RAS A;  4U9N A;  4ICH A;  5FHP A;  4MO7 A;  2IU5 A;  2PBX A;  5D1R A;  2HXO A;  3FK7 A;  3KYL A;  3VIB A;  2ZOZ A;  4YZE A;  5K7F A;  3COL A;  3ON2 A;  2G7G A;  3TP0 A;  4I6Z A;  4L62 A;  3HTH A;  2I10 A;  2NX4 A;  5K7H A;  2F07 A;  2X9D A;  4I76 A;  2R7X A;  4B3A A;  3ANG A;  3Q3S A;  4OD5 A;  4UDS A;  5J3L A;  2QIB A;  2Y31 A;  3ON4 A;  3BJB A;  3CCY A;  3SFI A;  2GBY A;  2QTQ A;  2Y30 A;  3EUP A;  5F08 A;  3CJD A;  3ANP A;  2R7Q A;  2FX0 A;  2HYJ A;  1ZK8 A;  4GCK A;  3JSJ A;  3HE0 A;  3CDL A;  5CW8 A;  3F1B A;  2UXI A;  4IRV A;  5CXI A;  2R7U A;  3PPB A;  3GZI A;  4XK4 A;  4ME9 A;  1JUM A;  3ZQF A;  2XGC A;  3BR6 A;  3PAS A;  3BR1 A;  2DTZ A;  3RH2 A;  3BTC A;  3IUV A;  4JKZ A;  1QVU A;  3VW0 A;  2R7R A;  2ID6 A;  3Q0W A;  3LSR A;  2OPT A;  1SGM A;  2FD5 A;  1JUS A;  3DU6 A;  3V6G A;  3VTI A;  3NS4 A;  2TCT A;  3K8P C;  3BR2 A;  3BR3 A;  2HQ5 A;  3LOC A;  3KZ9 A;  5EYR A;  2RAE A;  2ZCN A;  1ZKG A;  3CWR A;  5HAW A;  3O60 A;  5CXG A;  3G1L A;  5DAJ A;  4U9L A;  3HGG A;  2G3B A;  5F1J A;  2R7W A;  5F0H A;  4PXI A;  3ZQL A;  3LJL A;  2QCO A;  5IOZ A;  3LHQ A;  2R7T A;  2G7L A;  4X1E A;  2WGB A;  4V2F A;  3NI7 A;  5FMP A;  4AF5 A;  3PM1 A;  3HTJ A;  2WUI A;  2IAI A;  2R7O A;  2W53 A;  2NP3 A;  3O8G A;  2X6O A;  3VW2 A;  2YVH A;  3DPJ A;  4HKU A;  3MVP A;  1QVT A;  5IPA A;  2QKO A;  1U9N A;  4AC0 A;  3ZQG A;  4DW6 A;  3DCF A;  2UXH A;  5C4Y A;  2RHA A;  3Q0U A;  5GP9 A;  3VOX A;  3E7Q A;  2ZY9 A;  1JTX A;  3DEW A;  3F0C A;  2DG7 A;  2UXP A;  4ACI A;  2G0E A;  5F0F A;  2EH3 A;  1JT6 A;  2HXI A;  3S5R A;  2OER A;  1UI6 A;  5GPA A;  2R7V A;  5D18 A;  2GFN A;  3C07 A;  3LSP A;  3MNL A;  5AQC A;  3G1M A;  3IH4 A;  5GPC A;  2JJ7 A;  3LSJ A;  3IH3 A;  2PFV A;  2R7S A;  1T33 A;  2FJ1 A;  2ZCM A;  4AC6 A;  2JK3 A;  2A2F X;  2NS8 A;  2XPV A;  4W97 A;  2XB5 A;  3NXC A;  4MK6 A;  2XGD A;  2XRL A;  2XPU A;  4D7N A;  3QKX A;  2YVX A;  4M3F A;  3VW1 A;  3BQZ A;  1JUP A;  3VUQ A;  2QOP A;  2IEK A;  4KWA A;  1A6I A;  3NPI A;  3P9T A;  3V78 A;  4D5F A;  3QPS A;  3BTI A;  3QBM A;  3ZQI A;  3KKC A;  5IP6 A;  5FKM A;  4GCT A;  3BTJ A;  2DG8 A;  2G7S A;  3NNR A;  2PZ9 A;  3FHN A;  5F0C A;  3C2B A;  5FKK A;  3WHB A;  3HTI A;  2FJI 1;  2FQ4 A; 
#chains in the Genus database with same CATH homology
 4IRV A;  2R7V A;  2R7X A;  4OD5 A;  2R7U A;  4DVY P;  2B3W A;  2R7O A;  4OD4 A;  3DU5 A;  2R7W A;  3KYL A;  3VTI A;  3DU6 A;  3NS4 A;  3K8P C;  5CQG A;  2B1E A;  2PFV A;  2R7Q A;  2R7T A;  2R7S A;  3FHN A;  2R7R A;  2FJI 1;  3SWH A;  4C2M A;  2A2F X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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