4IRVA

Structure of the helicobacter pylori caga oncogene bound to the human tumor suppressor apoptosis-stimulating protein of p53-2
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
198
structure length
197
Chain Sequence
QQFINNLQVAFIKVDNVVASFDPDQKPIVDKNDRDNRQAFDGISQLREEYSNKAIKNPTKKNQYFSDFIDKSNDLINKDNLIDVESSTKSFQKFGDQRYQIFTSWVSHQKDPSKINTRSIRNFMENIIQPPIPDDKEKAEFLKSAKQSFAGIIIGNQIRTDQKFMGVFDESLKERQEAEKGGPTGGDWLDIFLSFIF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
molecule keywords Cytotoxicity-associated immunodominant antigen
publication title Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.
pubmed doi rcsb
source organism Helicobacter pylori
total genus 76
structure length 197
sequence length 198
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.357.130 Mainly Alpha Orthogonal Bundle Tetracycline Repressor; domain 2 Tetracycline Repressor; domain 2 4irvA00
4DVYP 4IRVA
chains in the Genus database with same CATH superfamily
2DG8A 2HQ5A 1JUMA 3NNRA 3FK6A 3VP5A 4AUXA 3HTIA 3LSPA 3ZQFA 3BTJA 2O7TA 2TRTA 5HBUA 2Y2ZA 4GFKA 1ZKGA 2JJ7A 3ZQGA 4V2GA 2R7WA 5D19A 1Z0XA 3VVXA 3GZIA 1JUPA 2TCTA 3FHNA 2ZCXA 2RHAA 2QIBA 2V57A 3BR6A 1U9NA 2D6YA 4M3GA 2G3BA 3O8GA 5FKKA 3VW0A 3RD3A 2XB5A 3VTIA 5HSZA 4ICHA 3B81A 3HE0A 3HIMA 5C4YA 5D1RA 2F07A 5EZHA 2R7XA 2X9DA 4JYKA 3VOXA 5CQGA 4GCKA 3VW1A 3KKCA 3BNIA 5IPAA 2R7SA 2WGBA 2REKA 3NI7A 1UI5A 4HKUA 3C07A 4D7MA 2UXIA 3VOKA 3DPJA 2GENA 3O60A 4DVYP 5F1JA 4G12A 2GUHA 3B6AA 3ZQIA 3TP3A 2VKEA 3NRGA 2YVHA 3Q0UA 2RAEA 4WIBA 3PM1A 4M3BA 2X6OA 2FJI1 3ANPA 5F27A 2NS7A 5K7FA 2R7UA 3LSJA 2XGEA 3KNWA 3HGYA 2NX4A 3SDGA 4M3EA 3VIBA 5F0FA 3K8PC 2XGCA 2DTZA 2QTQA 4NELA 3EGQA 3VVZA 2ID3A 5GPCA 2GFNA 2Q24A 1VI0A 4JL3A 2XRLA 2XGDA 5HAWA 4NN1A 2OI8A 5F08A 2ZOYA 4JNNA 4C2MA 1JT0A 2HYTA 5EZGA 5IP6A 2UXUA 3AQSA 1QVUA 2G7GA 4U9LA 4B1RA 2PFVA 2A2FX 2G7SA 3BT9A 2HXIA 1RKTA 4OD5A 1JTYA 4KWAA 3RH2A 4W97A 3B6CA 4ACIA 2IU5A 4OD4A 2B3WA 2ZB9A 2HXOA 3BCGA 3F1BA 1SGMA 4ABZA 5IOZA 1T33A 5D18A 3O8HA 5AQCA 3IH3A 2VKVA 2NP5A 4MK6A 5F0CA 2XDNA 3QQAA 3BR0A 3S5RA 3KZ9A 3BTLA 5EFYA 1U9OA 3BTIA 3G1OA 2I10A 4ME9A 2JK3A 5J1UA 3IH2A 3DU6A 4XK4A 3E7QA 3V78A 3FK7A 5CW8A 2W53A 4X1EA 2IEKA 4AC6A 2R7TA 5K7HA 5FKLA 3BR2A 1Z77A 3VW2A 5J1RA 3QPSA 1JTXA 2NS8A 4CGRA 1BJZA 5FKNA 5F04A 3Q0VA 2IAIA 2WV1A 4DW6A 3LSRA 2O7OA 3BJBA 3DEWA 3HGGA 1JT6A 1QVTA 3ON4A 4I76A 3SWHA 2Y30A 2QWTA 5EYRA 2OPTA 3G1LA 5CXGA 3BQYA 4GCLA 3VVYA 3PASA 2ZY9A 3BTCA 3LWJA 2R7RA 3NS4A 2XPWA 4I6ZA 5GPAA 2XPUA 3AQTA 3BQZA 3HTAA 2WUIA 2OERA 3NXCA 1ORKA 1QPIA 3ANGA 4JKZA 2QCOA 5FKMA 4GFLA 5GP9A 3P9TA 3F0CA 4M3DA 5FGLA 5IOYA 2FQ4A 2ZCMA 1ZK8A 3G56A 3ZQHA 2ID6A 3GEUA 4UDSA 3BRUA 4B3AA 3V6GA 3DCFA 3G1MA 3BR3A 3HTJA 2R7OA 3DU5A 4D7NA 3FIWA 3MVPA 4YZEA 1RPWA 3LOCA 5CXIA 1A6IA 5K7ZA 2HYJA 3G7RA 4GCTA 3T6NA 2XPVA 2EH3A 2UXHA 2R7VA 2QOPA 3WHCA 5FHPA 2ZCNA 3CDLA 2HKUA 2IBDA 3BR1A 4MXMA 3HTHA 3QKXA 3QPLA 3KYLA 2UXOA 3VPRA 4D5CA 2YVEA 2FD5A 4D5FA 1JUSA 4M3FA 2UXPA 3LHQA 2ZOZA 3COLA 3VUQA 3Q3SA 4PXIA 2FBQA 2VPRA 1UI6A 3QBMA 4IRVA 3IUVA 5FMPA 3TP0A 2YVXA 2OF7A 3CJDA 3BHQA 3ON2A 2G7LA 2G0EA 4MO7A 2FX0A 2GBYA 2B1EA 5J3LA 2DG7A 2PZ9A 2NP3A 4V2FA 2Y31A 5H9TA 3EUPA 2FJ1A 5DAJA 4W1UA 3KKDA 3IH4A 1RKWA 3PPBA 5K58A 1T56A 2PBXA 3CRJA 3SFIA 3NPIA 3BR5A 4U9NA 2QKOA 3CCYA 3ZQLA 4AC0A 3CWRA 5FKOA 3WHBA 3JSJA 3C2BA 3LJLA 2R7QA 4L62A 5F0HA 3FRQA 4AF5A 3Q0WA 5J1YA 2RASA 3MNLA
chains in the Genus database with same CATH topology
2PFVA 2B1EA 2A2FX 2R7RA 3VTIA 3DU6A 3NS4A 2R7SA 4OD5A 3FHNA 2FJI1 2R7VA 2R7UA 2R7XA 4IRVA 2R7OA 2R7TA 2R7QA 3DU5A 4DVYP 4C2MA 3SWHA 4OD4A 2B3WA 5CQGA 3K8PC 3KYLA 2R7WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DVY P;  4IRV A; 
#chains in the Genus database with same CATH topology
 2DG8 A;  2HQ5 A;  1JUM A;  3NNR A;  3FK6 A;  3VP5 A;  4AUX A;  3HTI A;  3LSP A;  3ZQF A;  3BTJ A;  2O7T A;  2TRT A;  5HBU A;  2Y2Z A;  4GFK A;  1ZKG A;  2JJ7 A;  3ZQG A;  4V2G A;  2R7W A;  5D19 A;  1Z0X A;  3VVX A;  3GZI A;  1JUP A;  2TCT A;  3FHN A;  2ZCX A;  2RHA A;  2QIB A;  2V57 A;  3BR6 A;  1U9N A;  2D6Y A;  4M3G A;  2G3B A;  3O8G A;  5FKK A;  3VW0 A;  3RD3 A;  2XB5 A;  3VTI A;  5HSZ A;  4ICH A;  3B81 A;  3HE0 A;  3HIM A;  5C4Y A;  5D1R A;  2F07 A;  5EZH A;  2R7X A;  2X9D A;  4JYK A;  3VOX A;  5CQG A;  4GCK A;  3VW1 A;  3KKC A;  3BNI A;  5IPA A;  2R7S A;  2WGB A;  2REK A;  3NI7 A;  1UI5 A;  4HKU A;  3C07 A;  4D7M A;  2UXI A;  3VOK A;  3DPJ A;  2GEN A;  3O60 A;  4DVY P;  5F1J A;  4G12 A;  2GUH A;  3B6A A;  3ZQI A;  3TP3 A;  2VKE A;  3NRG A;  2YVH A;  3Q0U A;  2RAE A;  4WIB A;  3PM1 A;  4M3B A;  2X6O A;  2FJI 1;  3ANP A;  5F27 A;  2NS7 A;  5K7F A;  2R7U A;  3LSJ A;  2XGE A;  3KNW A;  3HGY A;  2NX4 A;  3SDG A;  4M3E A;  3VIB A;  5F0F A;  3K8P C;  2XGC A;  2DTZ A;  2QTQ A;  4NEL A;  3EGQ A;  3VVZ A;  2ID3 A;  5GPC A;  2GFN A;  2Q24 A;  1VI0 A;  4JL3 A;  2XRL A;  2XGD A;  5HAW A;  4NN1 A;  2OI8 A;  5F08 A;  2ZOY A;  4JNN A;  4C2M A;  1JT0 A;  2HYT A;  5EZG A;  5IP6 A;  2UXU A;  3AQS A;  1QVU A;  2G7G A;  4U9L A;  4B1R A;  2PFV A;  2A2F X;  2G7S A;  3BT9 A;  2HXI A;  1RKT A;  4OD5 A;  1JTY A;  4KWA A;  3RH2 A;  4W97 A;  3B6C A;  4ACI A;  2IU5 A;  4OD4 A;  2B3W A;  2ZB9 A;  2HXO A;  3BCG A;  3F1B A;  1SGM A;  4ABZ A;  5IOZ A;  1T33 A;  5D18 A;  3O8H A;  5AQC A;  3IH3 A;  2VKV A;  2NP5 A;  4MK6 A;  5F0C A;  2XDN A;  3QQA A;  3BR0 A;  3S5R A;  3KZ9 A;  3BTL A;  5EFY A;  1U9O A;  3BTI A;  3G1O A;  2I10 A;  4ME9 A;  2JK3 A;  5J1U A;  3IH2 A;  3DU6 A;  4XK4 A;  3E7Q A;  3V78 A;  3FK7 A;  5CW8 A;  2W53 A;  4X1E A;  2IEK A;  4AC6 A;  2R7T A;  5K7H A;  5FKL A;  3BR2 A;  1Z77 A;  3VW2 A;  5J1R A;  3QPS A;  1JTX A;  2NS8 A;  4CGR A;  1BJZ A;  5FKN A;  5F04 A;  3Q0V A;  2IAI A;  2WV1 A;  4DW6 A;  3LSR A;  2O7O A;  3BJB A;  3DEW A;  3HGG A;  1JT6 A;  1QVT A;  3ON4 A;  4I76 A;  3SWH A;  2Y30 A;  2QWT A;  5EYR A;  2OPT A;  3G1L A;  5CXG A;  3BQY A;  4GCL A;  3VVY A;  3PAS A;  2ZY9 A;  3BTC A;  3LWJ A;  2R7R A;  3NS4 A;  2XPW A;  4I6Z A;  5GPA A;  2XPU A;  3AQT A;  3BQZ A;  3HTA A;  2WUI A;  2OER A;  3NXC A;  1ORK A;  1QPI A;  3ANG A;  4JKZ A;  2QCO A;  5FKM A;  4GFL A;  5GP9 A;  3P9T A;  3F0C A;  4M3D A;  5FGL A;  5IOY A;  2FQ4 A;  2ZCM A;  1ZK8 A;  3G56 A;  3ZQH A;  2ID6 A;  3GEU A;  4UDS A;  3BRU A;  4B3A A;  3V6G A;  3DCF A;  3G1M A;  3BR3 A;  3HTJ A;  2R7O A;  3DU5 A;  4D7N A;  3FIW A;  3MVP A;  4YZE A;  1RPW A;  3LOC A;  5CXI A;  1A6I A;  5K7Z A;  2HYJ A;  3G7R A;  4GCT A;  3T6N A;  2XPV A;  2EH3 A;  2UXH A;  2R7V A;  2QOP A;  3WHC A;  5FHP A;  2ZCN A;  3CDL A;  2HKU A;  2IBD A;  3BR1 A;  4MXM A;  3HTH A;  3QKX A;  3QPL A;  3KYL A;  2UXO A;  3VPR A;  4D5C A;  2YVE A;  2FD5 A;  4D5F A;  1JUS A;  4M3F A;  2UXP A;  3LHQ A;  2ZOZ A;  3COL A;  3VUQ A;  3Q3S A;  4PXI A;  2FBQ A;  2VPR A;  1UI6 A;  3QBM A;  4IRV A;  3IUV A;  5FMP A;  3TP0 A;  2YVX A;  2OF7 A;  3CJD A;  3BHQ A;  3ON2 A;  2G7L A;  2G0E A;  4MO7 A;  2FX0 A;  2GBY A;  2B1E A;  5J3L A;  2DG7 A;  2PZ9 A;  2NP3 A;  4V2F A;  2Y31 A;  5H9T A;  3EUP A;  2FJ1 A;  5DAJ A;  4W1U A;  3KKD A;  3IH4 A;  1RKW A;  3PPB A;  5K58 A;  1T56 A;  2PBX A;  3CRJ A;  3SFI A;  3NPI A;  3BR5 A;  4U9N A;  2QKO A;  3CCY A;  3ZQL A;  4AC0 A;  3CWR A;  5FKO A;  3WHB A;  3JSJ A;  3C2B A;  3LJL A;  2R7Q A;  4L62 A;  5F0H A;  3FRQ A;  4AF5 A;  3Q0W A;  5J1Y A;  2RAS A;  3MNL A; 
#chains in the Genus database with same CATH homology
 2PFV A;  2B1E A;  2A2F X;  2R7R A;  3VTI A;  3DU6 A;  3NS4 A;  2R7S A;  4OD5 A;  3FHN A;  2FJI 1;  2R7V A;  2R7U A;  2R7X A;  4IRV A;  2R7O A;  2R7T A;  2R7Q A;  3DU5 A;  4DVY P;  4C2M A;  3SWH A;  4OD4 A;  2B3W A;  5CQG A;  3K8P C;  3KYL A;  2R7W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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