4IRVA

Structure of the helicobacter pylori caga oncogene bound to the human tumor suppressor apoptosis-stimulating protein of p53-2
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
198
structure length
197
Chain Sequence
b'QQFINNLQVAFIKVDNVVASFDPDQKPIVDKNDRDNRQAFDGISQLREEYSNKAIKNPTKKNQYFSDFIDKSNDLINKDNLIDVESSTKSFQKFGDQRYQIFTSWVSHQKDPSKINTRSIRNFMENIIQPPIPDDKEKAEFLKSAKQSFAGIIIGNQIRTDQKFMGVFDESLKERQEAEKGGPTGGDWLDIFLSFIF'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Cytotoxicity-associated immunodominant antigen
publication title Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.
pubmed doi rcsb
source organism Helicobacter pylori
molecule tags Protein binding
total genus 76
structure length 197
sequence length 198
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.357.130 Mainly Alpha Orthogonal Bundle Tetracycline Repressor; domain 2 Tetracycline Repressor; domain 2 4irvA00
4IRVA 4DVYP
chains in the Genus database with same CATH superfamily
1U9NA 4GCLA 3CWRA 3FIWA 3GZIA 1T33A 5HBUA 3BR0A 5F04A 2ZCNA 2XGDA 5K7HA 4B1RA 3BCGA 4V2FA 2JK3A 3BR6A 3C2BA 2VKEA 4GFKA 2NS8A 3VIBA 3HTHA 3ON2A 3BTCA 2A2FX 3CRJA 3Q3SA 3V78A 3KKDA 2IBDA 1QPIA 3QQAA 5FGLA 2OPTA 3NI7A 1RKTA 2GENA 5EYRA 5FKLA 3AQSA 4XK4A 2QOPA 4GCTA 3E7QA 3DCFA 3KKCA 3BR2A 1U9OA 2QWTA 3G7RA 2GBYA 3O60A 3TP3A 4D7MA 2ZCMA 3DU5A 2ZY9A 2R7QA 2XGCA 1A6IA 3HGGA 4WIBA 2OF7A 1JT6A 4D7NA 4UDSA 3NPIA 2UXOA 2PBXA 4I6ZA 4AC6A 3VVYA 4HKUA 3LSPA 3NRGA 5K7FA 3JSJA 3NXCA 2G7SA 3HIMA 3AQTA 3B81A 4U9LA 3BTJA 2XPVA 2HKUA 2NS7A 3PASA 3FHNA 2G7GA 3BRUA 3F0CA 3DU6A 3KNWA 3VVXA 3BHQA 2WUIA 2REKA 5IOYA 3NNRA 4GFLA 3COLA 5F0FA 3VW0A 3QBMA 3VW1A 4CGRA 2G0EA 3BJBA 3CDLA 2I10A 4YZEA 3HGYA 4ABZA 2X6OA 5DAJA 3Q0WA 4D5CA 3O8GA 3HTJA 2XRLA 4I76A 3PM1A 5EZHA 1ZK8A 2XGEA 3BQZA 2W53A 5K7ZA 3WHBA 2X9DA 1JTXA 3CJDA 2Q24A 2FQ4A 3LWJA 2HYJA 4MK6A 2RASA 5FKNA 3G1LA 2FJ1A 5HSZA 3HTIA 3KZ9A 5FHPA 3VOKA 1ORKA 3BR1A 4IRVA 3DPJA 3F1BA 4DW6A 3ANPA 3RD3A 2GUHA 3LOCA 3WHCA 1JTYA 2DG7A 2QIBA 2B1EA 2PFVA 3NS4A 2UXHA 2QCOA 3VP5A 2F07A 3BT9A 2XPUA 2R7XA 2IAIA 3B6AA 2XDNA 2OI8A 3IH3A 2VKVA 5J1UA 3V6GA 3RH2A 2VPRA 2R7WA 5CQGA 3BR3A 3C07A 5C4YA 2R7OA 4NN1A 5F0CA 5AQCA 2R7TA 2D6YA 3LSRA 3MNLA 3EUPA 3BTIA 4MO7A 2B3WA 5K58A 2XB5A 5J3LA 2HXOA 2JJ7A 2GFNA 4M3FA 3LHQA 4JL3A 4PXIA 3SDGA 2Y30A 4M3GA 4JYKA 4L62A 2HQ5A 3DEWA 2R7VA 2DTZA 3IUVA 3Q0VA 4KWAA 4DVYP 3MVPA 4OD4A 2G3BA 2PZ9A 4V2GA 5GPAA 2ID3A 5D1RA 2WGBA 3B6CA 3ANGA 4AUXA 1UI5A 5D19A 2IU5A 1Z77A 2R7UA 2YVHA 2YVEA 5CXIA 5CXGA 3ZQHA 3ZQFA 1RKWA 5GP9A 3IH2A 3P9TA 5EFYA 2TRTA 3PPBA 2QTQA 4G12A 2R7RA 3BQYA 5FKMA 1SGMA 1JUSA 3SFIA 2ID6A 5F1JA 3BNIA 1VI0A 2TCTA 3ZQIA 2NP3A 2O7OA 2Y31A 2FX0A 1RPWA 2R7SA 5GPCA 4OD5A 2Y2ZA 3QKXA 4NELA 3K8PC 3HE0A 5HAWA 3VVZA 2FBQA 2IEKA 2DG8A 3QPSA 2G7LA 4JKZA 4X1EA 3ZQLA 5F0HA 3TP0A 3KYLA 3SWHA 3CCYA 1JUPA 2NX4A 4M3DA 5IOZA 4AF5A 4M3BA 3LSJA 3VPRA 4ICHA 3T6NA 3VTIA 3Q0UA 4GCKA 5FMPA 1QVUA 3BTLA 2ZCXA 5IP6A 4C2MA 4W1UA 4B3AA 3BR5A 2ZOZA 2RHAA 2FD5A 1QVTA 2WV1A 5FKOA 5FKKA 4D5FA 1T56A 5J1RA 5CW8A 3VOXA 2RAEA 3G56A 2XPWA 3ON4A 3VUQA 2O7TA 2V57A 4U9NA 3FK6A 3O8HA 3IH4A 2QKOA 4W97A 3FK7A 2ZB9A 5D18A 4AC0A 1UI6A 1JUMA 1JT0A 1BJZA 3G1OA 3HTAA 4MXMA 4ACIA 3S5RA 5F27A 2EH3A 2NP5A 2FJI1 2YVXA 5IPAA 2ZOYA 5J1YA 5H9TA 3VW2A 3G1MA 3ZQGA 3LJLA 5EZGA 3QPLA 4M3EA 2UXUA 1Z0XA 3FRQA 2HXIA 3GEUA 1ZKGA 2UXPA 2UXIA 2HYTA 3EGQA 4ME9A 2OERA 5F08A 4JNNA
chains in the Genus database with same CATH topology
3DU6A 4DVYP 2R7RA 4OD4A 2R7XA 4IRVA 2FJI1 3K8PC 3DU5A 3VTIA 2B3WA 2R7UA 2R7QA 5CQGA 4C2MA 2R7WA 2R7OA 2B1EA 2PFVA 2A2FX 3FHNA 2R7VA 3KYLA 3SWHA 2R7SA 2R7TA 3NS4A 4OD5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IRV A;  4DVY P; 
#chains in the Genus database with same CATH topology
 1U9N A;  4GCL A;  3CWR A;  3FIW A;  3GZI A;  1T33 A;  5HBU A;  3BR0 A;  5F04 A;  2ZCN A;  2XGD A;  5K7H A;  4B1R A;  3BCG A;  4V2F A;  2JK3 A;  3BR6 A;  3C2B A;  2VKE A;  4GFK A;  2NS8 A;  3VIB A;  3HTH A;  3ON2 A;  3BTC A;  2A2F X;  3CRJ A;  3Q3S A;  3V78 A;  3KKD A;  2IBD A;  1QPI A;  3QQA A;  5FGL A;  2OPT A;  3NI7 A;  1RKT A;  2GEN A;  5EYR A;  5FKL A;  3AQS A;  4XK4 A;  2QOP A;  4GCT A;  3E7Q A;  3DCF A;  3KKC A;  3BR2 A;  1U9O A;  2QWT A;  3G7R A;  2GBY A;  3O60 A;  3TP3 A;  4D7M A;  2ZCM A;  3DU5 A;  2ZY9 A;  2R7Q A;  2XGC A;  1A6I A;  3HGG A;  4WIB A;  2OF7 A;  1JT6 A;  4D7N A;  4UDS A;  3NPI A;  2UXO A;  2PBX A;  4I6Z A;  4AC6 A;  3VVY A;  4HKU A;  3LSP A;  3NRG A;  5K7F A;  3JSJ A;  3NXC A;  2G7S A;  3HIM A;  3AQT A;  3B81 A;  4U9L A;  3BTJ A;  2XPV A;  2HKU A;  2NS7 A;  3PAS A;  3FHN A;  2G7G A;  3BRU A;  3F0C A;  3DU6 A;  3KNW A;  3VVX A;  3BHQ A;  2WUI A;  2REK A;  5IOY A;  3NNR A;  4GFL A;  3COL A;  5F0F A;  3VW0 A;  3QBM A;  3VW1 A;  4CGR A;  2G0E A;  3BJB A;  3CDL A;  2I10 A;  4YZE A;  3HGY A;  4ABZ A;  2X6O A;  5DAJ A;  3Q0W A;  4D5C A;  3O8G A;  3HTJ A;  2XRL A;  4I76 A;  3PM1 A;  5EZH A;  1ZK8 A;  2XGE A;  3BQZ A;  2W53 A;  5K7Z A;  3WHB A;  2X9D A;  1JTX A;  3CJD A;  2Q24 A;  2FQ4 A;  3LWJ A;  2HYJ A;  4MK6 A;  2RAS A;  5FKN A;  3G1L A;  2FJ1 A;  5HSZ A;  3HTI A;  3KZ9 A;  5FHP A;  3VOK A;  1ORK A;  3BR1 A;  4IRV A;  3DPJ A;  3F1B A;  4DW6 A;  3ANP A;  3RD3 A;  2GUH A;  3LOC A;  3WHC A;  1JTY A;  2DG7 A;  2QIB A;  2B1E A;  2PFV A;  3NS4 A;  2UXH A;  2QCO A;  3VP5 A;  2F07 A;  3BT9 A;  2XPU A;  2R7X A;  2IAI A;  3B6A A;  2XDN A;  2OI8 A;  3IH3 A;  2VKV A;  5J1U A;  3V6G A;  3RH2 A;  2VPR A;  2R7W A;  5CQG A;  3BR3 A;  3C07 A;  5C4Y A;  2R7O A;  4NN1 A;  5F0C A;  5AQC A;  2R7T A;  2D6Y A;  3LSR A;  3MNL A;  3EUP A;  3BTI A;  4MO7 A;  2B3W A;  5K58 A;  2XB5 A;  5J3L A;  2HXO A;  2JJ7 A;  2GFN A;  4M3F A;  3LHQ A;  4JL3 A;  4PXI A;  3SDG A;  2Y30 A;  4M3G A;  4JYK A;  4L62 A;  2HQ5 A;  3DEW A;  2R7V A;  2DTZ A;  3IUV A;  3Q0V A;  4KWA A;  4DVY P;  3MVP A;  4OD4 A;  2G3B A;  2PZ9 A;  4V2G A;  5GPA A;  2ID3 A;  5D1R A;  2WGB A;  3B6C A;  3ANG A;  4AUX A;  1UI5 A;  5D19 A;  2IU5 A;  1Z77 A;  2R7U A;  2YVH A;  2YVE A;  5CXI A;  5CXG A;  3ZQH A;  3ZQF A;  1RKW A;  5GP9 A;  3IH2 A;  3P9T A;  5EFY A;  2TRT A;  3PPB A;  2QTQ A;  4G12 A;  2R7R A;  3BQY A;  5FKM A;  1SGM A;  1JUS A;  3SFI A;  2ID6 A;  5F1J A;  3BNI A;  1VI0 A;  2TCT A;  3ZQI A;  2NP3 A;  2O7O A;  2Y31 A;  2FX0 A;  1RPW A;  2R7S A;  5GPC A;  4OD5 A;  2Y2Z A;  3QKX A;  4NEL A;  3K8P C;  3HE0 A;  5HAW A;  3VVZ A;  2FBQ A;  2IEK A;  2DG8 A;  3QPS A;  2G7L A;  4JKZ A;  4X1E A;  3ZQL A;  5F0H A;  3TP0 A;  3KYL A;  3SWH A;  3CCY A;  1JUP A;  2NX4 A;  4M3D A;  5IOZ A;  4AF5 A;  4M3B A;  3LSJ A;  3VPR A;  4ICH A;  3T6N A;  3VTI A;  3Q0U A;  4GCK A;  5FMP A;  1QVU A;  3BTL A;  2ZCX A;  5IP6 A;  4C2M A;  4W1U A;  4B3A A;  3BR5 A;  2ZOZ A;  2RHA A;  2FD5 A;  1QVT A;  2WV1 A;  5FKO A;  5FKK A;  4D5F A;  1T56 A;  5J1R A;  5CW8 A;  3VOX A;  2RAE A;  3G56 A;  2XPW A;  3ON4 A;  3VUQ A;  2O7T A;  2V57 A;  4U9N A;  3FK6 A;  3O8H A;  3IH4 A;  2QKO A;  4W97 A;  3FK7 A;  2ZB9 A;  5D18 A;  4AC0 A;  1UI6 A;  1JUM A;  1JT0 A;  1BJZ A;  3G1O A;  3HTA A;  4MXM A;  4ACI A;  3S5R A;  5F27 A;  2EH3 A;  2NP5 A;  2FJI 1;  2YVX A;  5IPA A;  2ZOY A;  5J1Y A;  5H9T A;  3VW2 A;  3G1M A;  3ZQG A;  3LJL A;  5EZG A;  3QPL A;  4M3E A;  2UXU A;  1Z0X A;  3FRQ A;  2HXI A;  3GEU A;  1ZKG A;  2UXP A;  2UXI A;  2HYT A;  3EGQ A;  4ME9 A;  2OER A;  5F08 A;  4JNN A; 
#chains in the Genus database with same CATH homology
 3DU6 A;  4DVY P;  2R7R A;  4OD4 A;  2R7X A;  4IRV A;  2FJI 1;  3K8P C;  3DU5 A;  3VTI A;  2B3W A;  2R7U A;  2R7Q A;  5CQG A;  4C2M A;  2R7W A;  2R7O A;  2B1E A;  2PFV A;  2A2F X;  3FHN A;  2R7V A;  3KYL A;  3SWH A;  2R7S A;  2R7T A;  3NS4 A;  4OD5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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