4IRVA

Structure of the helicobacter pylori caga oncogene bound to the human tumor suppressor apoptosis-stimulating protein of p53-2
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
198
structure length
197
Chain Sequence
QQFINNLQVAFIKVDNVVASFDPDQKPIVDKNDRDNRQAFDGISQLREEYSNKAIKNPTKKNQYFSDFIDKSNDLINKDNLIDVESSTKSFQKFGDQRYQIFTSWVSHQKDPSKINTRSIRNFMENIIQPPIPDDKEKAEFLKSAKQSFAGIIIGNQIRTDQKFMGVFDESLKERQEAEKGGPTGGDWLDIFLSFIF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.
pubmed doi rcsb
molecule tags Protein binding
source organism Helicobacter pylori
molecule keywords Cytotoxicity-associated immunodominant antigen
total genus 76
structure length 197
sequence length 198
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.357.130 Mainly Alpha Orthogonal Bundle Tetracycline Repressor; domain 2 Tetracycline Repressor; domain 2 4irvA00
4IRVA 4DVYP
chains in the Genus database with same CATH superfamily
3BR0A 2WV1A 3V6GA 1QPIA 5F04A 5IP6A 2IBDA 3Q3SA 4KWAA 3G1OA 3TP3A 2XRLA 2FX0A 3BR1A 2HYTA 1QVUA 3P9TA 5FKKA 3Q0UA 5C4YA 3PPBA 5FKOA 1RPWA 1JUMA 5IOYA 3BJBA 2YVXA 3FRQA 4I6ZA 3KKCA 5GP9A 3BR5A 1U9NA 3VPRA 3BTJA 2ZCXA 2IAIA 2WUIA 4M3EA 5EZHA 5GPAA 5F1JA 3IH4A 4PXIA 1UI6A 2DTZA 2FJ1A 2UXHA 4DVYP 2VPRA 3VW0A 1JUPA 2XPUA 2X9DA 3FIWA 4M3FA 2W53A 2D6YA 5CXIA 2FBQA 3IUVA 3LSRA 2XGEA 4MXMA 3MNLA 4M3DA 3BTLA 3MVPA 3RD3A 4JKZA 5CW8A 3ZQGA 5GPCA 4ABZA 3LSPA 2GENA 1JTXA 5K7FA 2NS8A 3VVZA 3DU5A 1JT0A 2XPWA 2YVEA 3DPJA 3CCYA 3HE0A 5FGLA 5FHPA 4OD5A 2UXIA 2HXIA 4JYKA 3B6AA 2JJ7A 3QPLA 2EH3A 3SDGA 5IOZA 4ME9A 2OPTA 4B1RA 2G7SA 2NX4A 4IRVA 4YZEA 4B3AA 3QQAA 2UXUA 2FQ4A 2OI8A 2GBYA 1QVTA 3COLA 5F0CA 4CGRA 5CQGA 3EUPA 2IU5A 4NELA 5D1RA 2NS7A 5FKLA 2V57A 3NPIA 3NXCA 3ANGA 3BT9A 3KKDA 4L62A 2ID3A 3VVXA 2OERA 1T56A 2HQ5A 4D7NA 5K7HA 4X1EA 2JK3A 2Y31A 2WGBA 1A6IA 4GCKA 2ZOZA 3BTCA 2QCOA 2ZB9A 1RKTA 4M3GA 5J1UA 3VW1A 4V2FA 5HBUA 1Z0XA 3GEUA 3FK7A 3CRJA 5FKNA 4HKUA 3CJDA 3HTHA 4MO7A 3ZQFA 3B81A 3G56A 2PZ9A 3NRGA 2TCTA 3G1LA 4AF5A 4XK4A 5FKMA 3RH2A 2REKA 4W97A 5DAJA 3VOKA 3FK6A 3ZQIA 2IEKA 3ZQHA 3LHQA 2QTQA 4D5CA 3CWRA 3QBMA 4NN1A 4G12A 3DU6A 3G7RA 2G0EA 4UDSA 3C07A 2QIBA 2DG7A 3K8PC 3T6NA 2O7TA 3ON2A 3O60A 3BCGA 2XPVA 4AUXA 3BHQA 3DCFA 3NNRA 4W1UA 5J1RA 5J1YA 5J3LA 3VUQA 4GFLA 4GFKA 3BQZA 3O8GA 5HAWA 3VW2A 3HGYA 2R7RA 2O7OA 2ZCNA 2G7GA 4OD4A 2RHAA 3EGQA 1SGMA 2DG8A 3BTIA 2TRTA 5D18A 2FJI1 4I76A 4V2GA 3S5RA 2XGDA 2QOPA 3PASA 3WHBA 5F0FA 2B1EA 5H9TA 3BR3A 2Y2ZA 3HTIA 3ANPA 3VOXA 3ZQLA 5F0HA 3KYLA 3C2BA 1JUSA 3IH3A 3Q0WA 5EZGA 2R7TA 2NP5A 3BR6A 3NS4A 3O8HA 3SFIA 2ZCMA 3ON4A 3F1BA 1RKWA 3PM1A 5EFYA 3B6CA 1ZKGA 3F0CA 5FMPA 3HIMA 5HSZA 2UXPA 3DEWA 2R7QA 3AQTA 2OF7A 3QKXA 3KNWA 3Q0VA 3NI7A 1ZK8A 2ZOYA 3BR2A 4MK6A 2X6OA 2GFNA 3SWHA 4GCLA 4DW6A 3BNIA 4JNNA 3VIBA 2HYJA 2G7LA 5K58A 2B3WA 3E7QA 3HTJA 4AC0A 2PBXA 3LOCA 5CXGA 2PFVA 3LSJA 1ORKA 4GCTA 4ICHA 3TP0A 5F08A 2QWTA 2XB5A 3KZ9A 2R7VA 3BQYA 1T33A 2HKUA 2Q24A 2YVHA 2XDNA 2ID6A 3QPSA 3AQSA 2HXOA 2VKVA 3VTIA 3BRUA 2Y30A 3VP5A 4D5FA 5D19A 2F07A 3IH2A 3VVYA 3GZIA 4C2MA 2A2FX 1VI0A 1U9OA 2NP3A 3HGGA 3FHNA 2R7OA 3CDLA 2UXOA 3HTAA 5F27A 2R7XA 1UI5A 4JL3A 3JSJA 1JTYA 2FD5A 3G1MA 2I10A 2GUHA 1JT6A 3WHCA 2R7SA 2VKEA 2RASA 2R7UA 2QKOA 4D7MA 4AC6A 4M3BA 5IPAA 4U9LA 3LJLA 2R7WA 2RAEA 4WIBA 2G3BA 5AQCA 4ACIA 5K7ZA 2XGCA 5EYRA 3LWJA 1BJZA 4U9NA 2ZY9A 1Z77A 3V78A
chains in the Genus database with same CATH topology
3DU5A 4IRVA 2FJI1 2R7TA 3FHNA 2R7WA 3VTIA 2R7OA 3NS4A 2B3WA 4OD5A 2R7XA 2B1EA 2PFVA 3SWHA 3DU6A 5CQGA 2R7RA 2R7VA 4OD4A 2R7SA 3K8PC 4C2MA 2A2FX 3KYLA 2R7UA 2R7QA 4DVYP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IRV A;  4DVY P; 
#chains in the Genus database with same CATH topology
 3BR0 A;  2WV1 A;  3V6G A;  1QPI A;  5F04 A;  5IP6 A;  2IBD A;  3Q3S A;  4KWA A;  3G1O A;  3TP3 A;  2XRL A;  2FX0 A;  3BR1 A;  2HYT A;  1QVU A;  3P9T A;  5FKK A;  3Q0U A;  5C4Y A;  3PPB A;  5FKO A;  1RPW A;  1JUM A;  5IOY A;  3BJB A;  2YVX A;  3FRQ A;  4I6Z A;  3KKC A;  5GP9 A;  3BR5 A;  1U9N A;  3VPR A;  3BTJ A;  2ZCX A;  2IAI A;  2WUI A;  4M3E A;  5EZH A;  5GPA A;  5F1J A;  3IH4 A;  4PXI A;  1UI6 A;  2DTZ A;  2FJ1 A;  2UXH A;  4DVY P;  2VPR A;  3VW0 A;  1JUP A;  2XPU A;  2X9D A;  3FIW A;  4M3F A;  2W53 A;  2D6Y A;  5CXI A;  2FBQ A;  3IUV A;  3LSR A;  2XGE A;  4MXM A;  3MNL A;  4M3D A;  3BTL A;  3MVP A;  3RD3 A;  4JKZ A;  5CW8 A;  3ZQG A;  5GPC A;  4ABZ A;  3LSP A;  2GEN A;  1JTX A;  5K7F A;  2NS8 A;  3VVZ A;  3DU5 A;  1JT0 A;  2XPW A;  2YVE A;  3DPJ A;  3CCY A;  3HE0 A;  5FGL A;  5FHP A;  4OD5 A;  2UXI A;  2HXI A;  4JYK A;  3B6A A;  2JJ7 A;  3QPL A;  2EH3 A;  3SDG A;  5IOZ A;  4ME9 A;  2OPT A;  4B1R A;  2G7S A;  2NX4 A;  4IRV A;  4YZE A;  4B3A A;  3QQA A;  2UXU A;  2FQ4 A;  2OI8 A;  2GBY A;  1QVT A;  3COL A;  5F0C A;  4CGR A;  5CQG A;  3EUP A;  2IU5 A;  4NEL A;  5D1R A;  2NS7 A;  5FKL A;  2V57 A;  3NPI A;  3NXC A;  3ANG A;  3BT9 A;  3KKD A;  4L62 A;  2ID3 A;  3VVX A;  2OER A;  1T56 A;  2HQ5 A;  4D7N A;  5K7H A;  4X1E A;  2JK3 A;  2Y31 A;  2WGB A;  1A6I A;  4GCK A;  2ZOZ A;  3BTC A;  2QCO A;  2ZB9 A;  1RKT A;  4M3G A;  5J1U A;  3VW1 A;  4V2F A;  5HBU A;  1Z0X A;  3GEU A;  3FK7 A;  3CRJ A;  5FKN A;  4HKU A;  3CJD A;  3HTH A;  4MO7 A;  3ZQF A;  3B81 A;  3G56 A;  2PZ9 A;  3NRG A;  2TCT A;  3G1L A;  4AF5 A;  4XK4 A;  5FKM A;  3RH2 A;  2REK A;  4W97 A;  5DAJ A;  3VOK A;  3FK6 A;  3ZQI A;  2IEK A;  3ZQH A;  3LHQ A;  2QTQ A;  4D5C A;  3CWR A;  3QBM A;  4NN1 A;  4G12 A;  3DU6 A;  3G7R A;  2G0E A;  4UDS A;  3C07 A;  2QIB A;  2DG7 A;  3K8P C;  3T6N A;  2O7T A;  3ON2 A;  3O60 A;  3BCG A;  2XPV A;  4AUX A;  3BHQ A;  3DCF A;  3NNR A;  4W1U A;  5J1R A;  5J1Y A;  5J3L A;  3VUQ A;  4GFL A;  4GFK A;  3BQZ A;  3O8G A;  5HAW A;  3VW2 A;  3HGY A;  2R7R A;  2O7O A;  2ZCN A;  2G7G A;  4OD4 A;  2RHA A;  3EGQ A;  1SGM A;  2DG8 A;  3BTI A;  2TRT A;  5D18 A;  2FJI 1;  4I76 A;  4V2G A;  3S5R A;  2XGD A;  2QOP A;  3PAS A;  3WHB A;  5F0F A;  2B1E A;  5H9T A;  3BR3 A;  2Y2Z A;  3HTI A;  3ANP A;  3VOX A;  3ZQL A;  5F0H A;  3KYL A;  3C2B A;  1JUS A;  3IH3 A;  3Q0W A;  5EZG A;  2R7T A;  2NP5 A;  3BR6 A;  3NS4 A;  3O8H A;  3SFI A;  2ZCM A;  3ON4 A;  3F1B A;  1RKW A;  3PM1 A;  5EFY A;  3B6C A;  1ZKG A;  3F0C A;  5FMP A;  3HIM A;  5HSZ A;  2UXP A;  3DEW A;  2R7Q A;  3AQT A;  2OF7 A;  3QKX A;  3KNW A;  3Q0V A;  3NI7 A;  1ZK8 A;  2ZOY A;  3BR2 A;  4MK6 A;  2X6O A;  2GFN A;  3SWH A;  4GCL A;  4DW6 A;  3BNI A;  4JNN A;  3VIB A;  2HYJ A;  2G7L A;  5K58 A;  2B3W A;  3E7Q A;  3HTJ A;  4AC0 A;  2PBX A;  3LOC A;  5CXG A;  2PFV A;  3LSJ A;  1ORK A;  4GCT A;  4ICH A;  3TP0 A;  5F08 A;  2QWT A;  2XB5 A;  3KZ9 A;  2R7V A;  3BQY A;  1T33 A;  2HKU A;  2Q24 A;  2YVH A;  2XDN A;  2ID6 A;  3QPS A;  3AQS A;  2HXO A;  2VKV A;  3VTI A;  3BRU A;  2Y30 A;  3VP5 A;  4D5F A;  5D19 A;  2F07 A;  3IH2 A;  3VVY A;  3GZI A;  4C2M A;  2A2F X;  1VI0 A;  1U9O A;  2NP3 A;  3HGG A;  3FHN A;  2R7O A;  3CDL A;  2UXO A;  3HTA A;  5F27 A;  2R7X A;  1UI5 A;  4JL3 A;  3JSJ A;  1JTY A;  2FD5 A;  3G1M A;  2I10 A;  2GUH A;  1JT6 A;  3WHC A;  2R7S A;  2VKE A;  2RAS A;  2R7U A;  2QKO A;  4D7M A;  4AC6 A;  4M3B A;  5IPA A;  4U9L A;  3LJL A;  2R7W A;  2RAE A;  4WIB A;  2G3B A;  5AQC A;  4ACI A;  5K7Z A;  2XGC A;  5EYR A;  3LWJ A;  1BJZ A;  4U9N A;  2ZY9 A;  1Z77 A;  3V78 A; 
#chains in the Genus database with same CATH homology
 3DU5 A;  4IRV A;  2FJI 1;  2R7T A;  3FHN A;  2R7W A;  3VTI A;  2R7O A;  3NS4 A;  2B3W A;  4OD5 A;  2R7X A;  2B1E A;  2PFV A;  3SWH A;  3DU6 A;  5CQG A;  2R7R A;  2R7V A;  4OD4 A;  2R7S A;  3K8P C;  4C2M A;  2A2F X;  3KYL A;  2R7U A;  2R7Q A;  4DVY P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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