1FJMA

Protein serine/threonine phosphatase-1 (alpha isoform, type 1) complexed with microcystin-lr toxin
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
294
structure length
294
Chain Sequence
LNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords PROTEIN SERINE/THREONINE PHOSPHATASE-1 (ALPHA ISOFORM, TYPE
total genus 105
structure length 294
sequence length 294
chains with identical sequence B
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 1995-12-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 1fjmA00
2Q8UA 1USHA 4V0WA 2WDFA 4O4KA 2O8GA 5J28A 2A22A 3T1IA 2KKNA 4O43A 3IVEA 3C5WC 1II7A 4XPNA 4JA7A 2R17A 4ZVZA 4KKZA 1T71A 4V0VA 2BCDA 1WAO1 2IE4C 3IVDA 2NXFA 4M0VA 4F0ZA 3THOB 5HPEA 3RL3A 1T70A 4IL1A 1S3LA 4ZX2A 2GJUA 3LL8A 4H2FA 3P71C 3HVQA 5B8IA 1OIDA 2IAEC 1HP1A 2HYPA 3H69A 3IB8A 4HD0A 2DFJA 3H61A 3H67A 1OI8A 2P6BA 3ZTVA 4I5LC 1NNWA 4H2BA 1G5BA 4TUGA 3JYFA 3RL4A 1AUIA 4KBPA 2QJCA 2IE3C 5F3WA 3H64A 2NYLC 4DT2A 5JJTA 4MP0A 1XZWA 2AHDA 1FJMA 1UF3A 2QFRA 3AUZA 4H1YP 5INBA 4TUIA 1Z2XA 1QFCA 4MOYA 1HO5A 2HY1A 3FGAC 4Q7FA 4H1SA 4UT2A 3QFOA 3QG5C 1S3NA 2QFPA 3H63A 4FBQA 4YKEA 4UWQA 2Z06A 3K7VC 3H68A 5EQVA 4LTYA 4MOVA 1SU1A 2JOGA 5DNYA 4IYPC 3QFKA 4DHLA 1W24A 4H2IA 3TGHA 1U32A 4FBKA 1S3MA 2BDXA 2WDEA 1KBPA 2USHA 4OR9A 2NYMC 3THNA 3E7AA 1S8EA 5JPFA 2NPPC 5GTUA 3DSDA 3N5UA 3H62B 1MF8A 1UTEA 3ZU0A 3KBPA 4UT3A 4G9JA 1QHWA 2YVTA 1Z2WA 3EGGA 3E7BA 3RQZA 3V4YA 2Z1AA 4FBWA 2BQ8X 4O24A 3QFMA 1JK7A 3IB7A 2WDCA 3GVEA 3RL5A 3C9FA 3H60A 4WWLA 3QFNA 4UT3B 1V73A 2HYOA 4V0XA 4JA9A 4LACC 4LU9A 1IT6A 3DW8C 4O5GA 4J6OA 4DSYA 3AV0A 1WARA 3EGHA 3PSNA 4ORCA 2O8AA 2XMOA 2CV9A 2Z72A 4H2GA 4ORBA 1S70A 4NZVA 4FCXA 5IOHA 3DSCA 1XM7A 3PSOA 4I5NC 3CK2A 1M63A 1TCOA 1HPUA 3ICFA 1OIEA 3K7WC 4B2OA 5JPEA 2WDDA 4ORAA 3H66A 2ZBMA 5C1VA 1S95A
chains in the Genus database with same CATH superfamily
2Q8UA 1USHA 4V0WA 2WDFA 3D03A 4O4KA 2O8GA 5J28A 2ZO9B 2A22A 3T1IA 2KKNA 4O43A 3IVEA 3C5WC 1II7A 4XPNA 4JA7A 2R17A 4ZVZA 4KKZA 1T71A 4V0VA 2BCDA 1WAO1 2IE4C 3IVDA 2NXFA 4M0VA 4F0ZA 3THOB 5HPEA 3RL3A 1T70A 4IL1A 1S3LA 4ZX2A 2GJUA 3LL8A 4H2FA 3P71C 3HVQA 3FLOA 1OIDA 2IAEC 1HP1A 5B8IA 2HYPA 2YEQA 3H69A 3IB8A 4HD0A 2DFJA 3H61A 3H67A 1OI8A 2P6BA 3ZTVA 4I5LC 1NNWA 4H2BA 1G5BA 4TUGA 3JYFA 3RL4A 1AUIA 4KBPA 2QJCA 2IE3C 5F3WA 3H64A 2NYLC 4DT2A 5JJTA 4MP0A 2DXNA 1XZWA 2AHDA 1FJMA 1UF3A 2QFRA 3AUZA 4H1YP 5INBA 4TUIA 3E0JA 1Z2XA 1QFCA 4MOYA 1HO5A 2HY1A 3FGAC 4Q7FA 4H1SA 4UT2A 3QFOA 3QG5C 1S3NA 2QFPA 3H63A 4FBQA 4YKEA 4UWQA 2Z06A 3K7VC 3H68A 5EQVA 4LTYA 4MOVA 1SU1A 2JOGA 5DNYA 4IYPC 3QFKA 4DHLA 1W24A 4H2IA 3TGHA 1U32A 4FBKA 1S3MA 2BDXA 2WDEA 1KBPA 2USHA 4OR9A 2NYMC 3THNA 3E7AA 1S8EA 5JPFA 2NPPC 5GTUA 3DSDA 3N5UA 3H62B 1MF8A 1UTEA 3ZU0A 3KBPA 4UT3A 4G9JA 1QHWA 2YVTA 1Z2WA 3EGGA 3E7BA 3RQZA 3V4YA 2Z1AA 2ZOAA 4FBWA 2BQ8X 4O24A 3QFMA 1JK7A 3IB7A 2WDCA 3GVEA 3RL5A 3C9FA 3H60A 4WWLA 3QFNA 4UT3B 1V73A 2HYOA 4V0XA 4JA9A 4LACC 4LU9A 1IT6A 3DW8C 4O5GA 4J6OA 4DSYA 3AV0A 1WARA 3EGHA 3PSNA 4ORCA 2O8AA 2XMOA 2CV9A 2Z72A 4H2GA 4ORBA 1S70A 4NZVA 4FCXA 5IOHA 3DSCA 1XM7A 2DXLA 3PSOA 4I5NC 3CK2A 1M63A 1TCOA 1HPUA 3ICFA 1OIEA 3K7WC 4B2OA 5JPEA 2WDDA 4ORAA 3H66A 2ZBMA 5C1VA 1S95A
chains in the Genus database with same CATH topology
2Q8UA 1USHA 4V0WA 2WDFA 3D03A 4O4KA 2O8GA 5J28A 2ZO9B 2A22A 3T1IA 2KKNA 4O43A 3IVEA 3C5WC 1II7A 4XPNA 4JA7A 2R17A 4ZVZA 4KKZA 1T71A 4V0VA 2BCDA 1WAO1 2IE4C 3IVDA 2NXFA 4M0VA 4F0ZA 3THOB 5HPEA 3RL3A 1T70A 4IL1A 1S3LA 4ZX2A 2GJUA 3LL8A 4H2FA 3P71C 3HVQA 3FLOA 1OIDA 2IAEC 1HP1A 5B8IA 2HYPA 2YEQA 3H69A 3IB8A 4HD0A 2DFJA 3H61A 3H67A 1OI8A 2P6BA 3ZTVA 4I5LC 1NNWA 4H2BA 1G5BA 4TUGA 3JYFA 3RL4A 1AUIA 4KBPA 2QJCA 2IE3C 5F3WA 3H64A 2NYLC 4DT2A 5JJTA 4MP0A 2DXNA 1XZWA 2AHDA 1FJMA 1UF3A 2QFRA 3AUZA 4H1YP 5INBA 4TUIA 3E0JA 1Z2XA 1QFCA 4MOYA 1HO5A 2HY1A 3FGAC 4Q7FA 4H1SA 4UT2A 3QFOA 3QG5C 1S3NA 2QFPA 3H63A 4FBQA 4YKEA 4UWQA 2Z06A 3K7VC 3H68A 5EQVA 4LTYA 4MOVA 1SU1A 2JOGA 5DNYA 4IYPC 3QFKA 4DHLA 1W24A 4H2IA 3TGHA 1U32A 4FBKA 1S3MA 2BDXA 2WDEA 1KBPA 2USHA 4OR9A 2NYMC 3THNA 3E7AA 1S8EA 5JPFA 2NPPC 5GTUA 3DSDA 3N5UA 3H62B 1MF8A 1UTEA 3ZU0A 3KBPA 4UT3A 4G9JA 1QHWA 2YVTA 1Z2WA 3EGGA 3E7BA 3RQZA 3V4YA 2Z1AA 2ZOAA 4FBWA 2BQ8X 4O24A 3QFMA 1JK7A 3IB7A 2WDCA 3GVEA 3RL5A 3C9FA 3H60A 4WWLA 3QFNA 4UT3B 1V73A 2HYOA 4V0XA 4JA9A 4LACC 4LU9A 1IT6A 3DW8C 4O5GA 4J6OA 4DSYA 3AV0A 1WARA 3EGHA 3PSNA 4ORCA 2O8AA 2XMOA 2CV9A 2Z72A 4H2GA 4ORBA 1S70A 4NZVA 4FCXA 5IOHA 3DSCA 1XM7A 2DXLA 3PSOA 4I5NC 3CK2A 1M63A 1TCOA 1HPUA 3ICFA 1OIEA 3K7WC 4B2OA 5JPEA 2WDDA 4ORAA 3H66A 2ZBMA 5C1VA 1S95A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Q8U A;  1USH A;  4V0W A;  2WDF A;  4O4K A;  2O8G A;  5J28 A;  2A22 A;  3T1I A;  2KKN A;  4O43 A;  3IVE A;  3C5W C;  1II7 A;  4XPN A;  4JA7 A;  2R17 A;  4ZVZ A;  4KKZ A;  1T71 A;  4V0V A;  2BCD A;  1WAO 1;  2IE4 C;  3IVD A;  2NXF A;  4M0V A;  4F0Z A;  3THO B;  5HPE A;  3RL3 A;  1T70 A;  4IL1 A;  1S3L A;  4ZX2 A;  2GJU A;  3LL8 A;  4H2F A;  3P71 C;  3HVQ A;  5B8I A;  1OID A;  2IAE C;  1HP1 A;  2HYP A;  3H69 A;  3IB8 A;  4HD0 A;  2DFJ A;  3H61 A;  3H67 A;  1OI8 A;  2P6B A;  3ZTV A;  4I5L C;  1NNW A;  4H2B A;  1G5B A;  4TUG A;  3JYF A;  3RL4 A;  1AUI A;  4KBP A;  2QJC A;  2IE3 C;  5F3W A;  3H64 A;  2NYL C;  4DT2 A;  5JJT A;  4MP0 A;  1XZW A;  2AHD A;  1FJM A;  1UF3 A;  2QFR A;  3AUZ A;  4H1Y P;  5INB A;  4TUI A;  1Z2X A;  1QFC A;  4MOY A;  1HO5 A;  2HY1 A;  3FGA C;  4Q7F A;  4H1S A;  4UT2 A;  3QFO A;  3QG5 C;  1S3N A;  2QFP A;  3H63 A;  4FBQ A;  4YKE A;  4UWQ A;  2Z06 A;  3K7V C;  3H68 A;  5EQV A;  4LTY A;  4MOV A;  1SU1 A;  2JOG A;  5DNY A;  4IYP C;  3QFK A;  4DHL A;  1W24 A;  4H2I A;  3TGH A;  1U32 A;  4FBK A;  1S3M A;  2BDX A;  2WDE A;  1KBP A;  2USH A;  4OR9 A;  2NYM C;  3THN A;  3E7A A;  1S8E A;  5JPF A;  2NPP C;  5GTU A;  3DSD A;  3N5U A;  3H62 B;  1MF8 A;  1UTE A;  3ZU0 A;  3KBP A;  4UT3 A;  4G9J A;  1QHW A;  2YVT A;  1Z2W A;  3EGG A;  3E7B A;  3RQZ A;  3V4Y A;  2Z1A A;  4FBW A;  2BQ8 X;  4O24 A;  3QFM A;  1JK7 A;  3IB7 A;  2WDC A;  3GVE A;  3RL5 A;  3C9F A;  3H60 A;  4WWL A;  3QFN A;  4UT3 B;  1V73 A;  2HYO A;  4V0X A;  4JA9 A;  4LAC C;  4LU9 A;  1IT6 A;  3DW8 C;  4O5G A;  4J6O A;  4DSY A;  3AV0 A;  1WAR A;  3EGH A;  3PSN A;  4ORC A;  2O8A A;  2XMO A;  2CV9 A;  2Z72 A;  4H2G A;  4ORB A;  1S70 A;  4NZV A;  4FCX A;  5IOH A;  3DSC A;  1XM7 A;  3PSO A;  4I5N C;  3CK2 A;  1M63 A;  1TCO A;  1HPU A;  3ICF A;  1OIE A;  3K7W C;  4B2O A;  5JPE A;  2WDD A;  4ORA A;  3H66 A;  2ZBM A;  5C1V A;  1S95 A; 
#chains in the Genus database with same CATH topology
 2Q8U A;  1USH A;  4V0W A;  2WDF A;  3D03 A;  4O4K A;  2O8G A;  5J28 A;  2ZO9 B;  2A22 A;  3T1I A;  2KKN A;  4O43 A;  3IVE A;  3C5W C;  1II7 A;  4XPN A;  4JA7 A;  2R17 A;  4ZVZ A;  4KKZ A;  1T71 A;  4V0V A;  2BCD A;  1WAO 1;  2IE4 C;  3IVD A;  2NXF A;  4M0V A;  4F0Z A;  3THO B;  5HPE A;  3RL3 A;  1T70 A;  4IL1 A;  1S3L A;  4ZX2 A;  2GJU A;  3LL8 A;  4H2F A;  3P71 C;  3HVQ A;  3FLO A;  1OID A;  2IAE C;  1HP1 A;  5B8I A;  2HYP A;  2YEQ A;  3H69 A;  3IB8 A;  4HD0 A;  2DFJ A;  3H61 A;  3H67 A;  1OI8 A;  2P6B A;  3ZTV A;  4I5L C;  1NNW A;  4H2B A;  1G5B A;  4TUG A;  3JYF A;  3RL4 A;  1AUI A;  4KBP A;  2QJC A;  2IE3 C;  5F3W A;  3H64 A;  2NYL C;  4DT2 A;  5JJT A;  4MP0 A;  2DXN A;  1XZW A;  2AHD A;  1FJM A;  1UF3 A;  2QFR A;  3AUZ A;  4H1Y P;  5INB A;  4TUI A;  3E0J A;  1Z2X A;  1QFC A;  4MOY A;  1HO5 A;  2HY1 A;  3FGA C;  4Q7F A;  4H1S A;  4UT2 A;  3QFO A;  3QG5 C;  1S3N A;  2QFP A;  3H63 A;  4FBQ A;  4YKE A;  4UWQ A;  2Z06 A;  3K7V C;  3H68 A;  5EQV A;  4LTY A;  4MOV A;  1SU1 A;  2JOG A;  5DNY A;  4IYP C;  3QFK A;  4DHL A;  1W24 A;  4H2I A;  3TGH A;  1U32 A;  4FBK A;  1S3M A;  2BDX A;  2WDE A;  1KBP A;  2USH A;  4OR9 A;  2NYM C;  3THN A;  3E7A A;  1S8E A;  5JPF A;  2NPP C;  5GTU A;  3DSD A;  3N5U A;  3H62 B;  1MF8 A;  1UTE A;  3ZU0 A;  3KBP A;  4UT3 A;  4G9J A;  1QHW A;  2YVT A;  1Z2W A;  3EGG A;  3E7B A;  3RQZ A;  3V4Y A;  2Z1A A;  2ZOA A;  4FBW A;  2BQ8 X;  4O24 A;  3QFM A;  1JK7 A;  3IB7 A;  2WDC A;  3GVE A;  3RL5 A;  3C9F A;  3H60 A;  4WWL A;  3QFN A;  4UT3 B;  1V73 A;  2HYO A;  4V0X A;  4JA9 A;  4LAC C;  4LU9 A;  1IT6 A;  3DW8 C;  4O5G A;  4J6O A;  4DSY A;  3AV0 A;  1WAR A;  3EGH A;  3PSN A;  4ORC A;  2O8A A;  2XMO A;  2CV9 A;  2Z72 A;  4H2G A;  4ORB A;  1S70 A;  4NZV A;  4FCX A;  5IOH A;  3DSC A;  1XM7 A;  2DXL A;  3PSO A;  4I5N C;  3CK2 A;  1M63 A;  1TCO A;  1HPU A;  3ICF A;  1OIE A;  3K7W C;  4B2O A;  5JPE A;  2WDD A;  4ORA A;  3H66 A;  2ZBM A;  5C1V A;  1S95 A; 
#chains in the Genus database with same CATH homology
 2Q8U A;  1USH A;  4V0W A;  2WDF A;  3D03 A;  4O4K A;  2O8G A;  5J28 A;  2ZO9 B;  2A22 A;  3T1I A;  2KKN A;  4O43 A;  3IVE A;  3C5W C;  1II7 A;  4XPN A;  4JA7 A;  2R17 A;  4ZVZ A;  4KKZ A;  1T71 A;  4V0V A;  2BCD A;  1WAO 1;  2IE4 C;  3IVD A;  2NXF A;  4M0V A;  4F0Z A;  3THO B;  5HPE A;  3RL3 A;  1T70 A;  4IL1 A;  1S3L A;  4ZX2 A;  2GJU A;  3LL8 A;  4H2F A;  3P71 C;  3HVQ A;  3FLO A;  1OID A;  2IAE C;  1HP1 A;  5B8I A;  2HYP A;  2YEQ A;  3H69 A;  3IB8 A;  4HD0 A;  2DFJ A;  3H61 A;  3H67 A;  1OI8 A;  2P6B A;  3ZTV A;  4I5L C;  1NNW A;  4H2B A;  1G5B A;  4TUG A;  3JYF A;  3RL4 A;  1AUI A;  4KBP A;  2QJC A;  2IE3 C;  5F3W A;  3H64 A;  2NYL C;  4DT2 A;  5JJT A;  4MP0 A;  2DXN A;  1XZW A;  2AHD A;  1FJM A;  1UF3 A;  2QFR A;  3AUZ A;  4H1Y P;  5INB A;  4TUI A;  3E0J A;  1Z2X A;  1QFC A;  4MOY A;  1HO5 A;  2HY1 A;  3FGA C;  4Q7F A;  4H1S A;  4UT2 A;  3QFO A;  3QG5 C;  1S3N A;  2QFP A;  3H63 A;  4FBQ A;  4YKE A;  4UWQ A;  2Z06 A;  3K7V C;  3H68 A;  5EQV A;  4LTY A;  4MOV A;  1SU1 A;  2JOG A;  5DNY A;  4IYP C;  3QFK A;  4DHL A;  1W24 A;  4H2I A;  3TGH A;  1U32 A;  4FBK A;  1S3M A;  2BDX A;  2WDE A;  1KBP A;  2USH A;  4OR9 A;  2NYM C;  3THN A;  3E7A A;  1S8E A;  5JPF A;  2NPP C;  5GTU A;  3DSD A;  3N5U A;  3H62 B;  1MF8 A;  1UTE A;  3ZU0 A;  3KBP A;  4UT3 A;  4G9J A;  1QHW A;  2YVT A;  1Z2W A;  3EGG A;  3E7B A;  3RQZ A;  3V4Y A;  2Z1A A;  2ZOA A;  4FBW A;  2BQ8 X;  4O24 A;  3QFM A;  1JK7 A;  3IB7 A;  2WDC A;  3GVE A;  3RL5 A;  3C9F A;  3H60 A;  4WWL A;  3QFN A;  4UT3 B;  1V73 A;  2HYO A;  4V0X A;  4JA9 A;  4LAC C;  4LU9 A;  1IT6 A;  3DW8 C;  4O5G A;  4J6O A;  4DSY A;  3AV0 A;  1WAR A;  3EGH A;  3PSN A;  4ORC A;  2O8A A;  2XMO A;  2CV9 A;  2Z72 A;  4H2G A;  4ORB A;  1S70 A;  4NZV A;  4FCX A;  5IOH A;  3DSC A;  1XM7 A;  2DXL A;  3PSO A;  4I5N C;  3CK2 A;  1M63 A;  1TCO A;  1HPU A;  3ICF A;  1OIE A;  3K7W C;  4B2O A;  5JPE A;  2WDD A;  4ORA A;  3H66 A;  2ZBM A;  5C1V A;  1S95 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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