2ZBMA

Crystal structure of i115m mutant cold-active protein tyrosine phosphatase
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
331
structure length
331
Chain Sequence
TEFDGPYVITPISGQSTAYWICDNRLKTTSIEKLQVNRPEHCGDLPETKLSSEIKQIMPDTYLGIKKVVALSDVHGQYDVLLTLLKKQKIIDSDGNWAFGEGHMVMTGDMFDRGHQVNEVLWFMYQLDQQARDAGGMVHLLMGNHEQMVLGGDLRYVHQRYDIATTLINRPYNKLYGADTEIGQWLRSKNTIIKINDVLYMHGGISSEWISRELTLDKANALYRANVDASKKSLKADDLLNFLFFGNGPTWYRGYFSETFTEAELDTILQHFNVNHIVVGHTSQERVLGLFHNKVIAVDSSIKVGKSGELLLLENNRLIRGLYDGTRETLQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The role of group bulkiness in the catalytic activity of psychrophile cold-active protein tyrosine phosphatase
pubmed doi rcsb
molecule keywords Protein-tyrosine-phosphatase
molecule tags Hydrolase
source organism Shewanella sp.
total genus 116
structure length 331
sequence length 331
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-10-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2zbmA00
2NXFA 4FCXA 2WDEA 3ZU0A 4V0XA 2BCDA 2YVTA 4IYPC 2QFRA 4FBQA 5INBA 3RQZA 4NZVA 4O5GA 4H2BA 4ZVZA 4XPNA 3LL8A 5GTUA 1U32A 3DSCA 4V0VA 1OIEA 2Z06A 3CK2A 3E7AA 3KBPA 3K7VC 4KKZA 1HO5A 4F0ZA 4O4KA 2DFJA 4WWLA 1V73A 4MOYA 3H64A 3IVDA 5J28A 4LACC 5DNYA 1USHA 3EGHA 2BDXA 3P71C 4JA9A 1HP1A 1W24A 2P6BA 3C9FA 3H60A 5JPFA 3AV0A 2GJUA 5C1VA 4O24A 1TCOA 3AUZA 3H61A 4ZX2A 4DSYA 4H1SA 1WAO1 4I5LC 5IOHA 3H66A 5EQVA 1S70A 3ICFA 4TUGA 3PSOA 4H2GA 2HYOA 1G5BA 3RL4A 3DSDA 5HPEA 4DT2A 3E7BA 1S95A 5F3WA 4YKEA 3H67A 2CV9A 2NPPC 2WDCA 4UT2A 4I5NC 1UTEA 3V4YA 1M63A 2QFPA 3C5WC 2HY1A 2KKNA 3QFOA 4ORBA 1OI8A 4UT3B 4HD0A 4H2IA 4IL1A 3QFNA 2IAEC 3IVEA 4KBPA 3IB8A 1S3MA 2AHDA 2O8GA 1S3NA 3FGAC 1QHWA 1T71A 5JJTA 1QFCA 5JPEA 4MP0A 1NNWA 3JYFA 3QFKA 4ORAA 4B2OA 1SU1A 1T70A 4JA7A 1XZWA 2XMOA 1WARA 4FBKA 3GVEA 3RL5A 2ZBMA 3THNA 3H62B 4LU9A 4LTYA 3TGHA 4M0VA 1OIDA 4UT3A 2O8AA 2IE4C 2WDFA 3N5UA 4TUIA 2JOGA 4MOVA 3THOB 1Z2WA 1Z2XA 4UWQA 1KBPA 2IE3C 1JK7A 1FJMA 2A22A 4DHLA 1II7A 2QJCA 1AUIA 1S3LA 3H63A 1UF3A 3H68A 3H69A 2USHA 4H2FA 2BQ8X 3QG5C 5B8IA 3K7WC 3IB7A 4FBWA 4O43A 3EGGA 2Z1AA 2Q8UA 4OR9A 4H1YP 1MF8A 3PSNA 4Q7FA 1XM7A 1IT6A 2Z72A 4ORCA 2HYPA 4V0WA 2NYMC 3DW8C 4G9JA 3T1IA 3ZTVA 3QFMA 3RL3A 2NYLC 1HPUA 1S8EA 4J6OA 2WDDA 2R17A 3HVQA
chains in the Genus database with same CATH superfamily
2NXFA 4FCXA 2WDEA 3D03A 3ZU0A 4V0XA 2BCDA 2YVTA 4IYPC 2QFRA 4FBQA 5INBA 3RQZA 4NZVA 4O5GA 4H2BA 4ZVZA 4XPNA 3LL8A 5GTUA 1U32A 3DSCA 4V0VA 1OIEA 2Z06A 3CK2A 3E7AA 3KBPA 3K7VC 4KKZA 1HO5A 4F0ZA 4O4KA 2DFJA 4WWLA 1V73A 4MOYA 3H64A 3IVDA 5J28A 4LACC 5DNYA 1USHA 3EGHA 2BDXA 3P71C 4JA9A 1HP1A 1W24A 2ZO9B 2P6BA 3C9FA 3H60A 5JPFA 3AV0A 2GJUA 5C1VA 4O24A 1TCOA 3AUZA 3H61A 4ZX2A 4DSYA 4H1SA 1WAO1 4I5LC 5IOHA 3H66A 2DXLA 5EQVA 1S70A 3ICFA 4TUGA 3PSOA 4H2GA 2HYOA 3E0JA 1G5BA 3RL4A 3DSDA 5HPEA 4DT2A 3E7BA 1S95A 5F3WA 4YKEA 3H67A 2CV9A 2NPPC 2WDCA 4UT2A 4I5NC 1UTEA 3V4YA 1M63A 2QFPA 3C5WC 2HY1A 2KKNA 3QFOA 4ORBA 1OI8A 4UT3B 4HD0A 4H2IA 4IL1A 3QFNA 2IAEC 3IVEA 4KBPA 3IB8A 1S3MA 3FLOA 2AHDA 2O8GA 1S3NA 3FGAC 1QHWA 1T71A 5JJTA 1QFCA 5JPEA 4MP0A 1NNWA 3JYFA 3QFKA 4ORAA 4B2OA 1SU1A 1T70A 4JA7A 1XZWA 2XMOA 1WARA 4FBKA 3GVEA 3RL5A 2ZBMA 3THNA 2YEQA 3H62B 4LU9A 4LTYA 3TGHA 4M0VA 1OIDA 4UT3A 2O8AA 2IE4C 2WDFA 3N5UA 4TUIA 2JOGA 4MOVA 3THOB 1Z2WA 1Z2XA 4UWQA 1KBPA 2IE3C 1JK7A 1FJMA 2A22A 4DHLA 1II7A 2QJCA 1AUIA 1S3LA 3H63A 1UF3A 2DXNA 3H68A 2USHA 3H69A 4H2FA 2BQ8X 2ZOAA 3QG5C 5B8IA 3K7WC 3IB7A 4FBWA 4O43A 3EGGA 2Z1AA 2Q8UA 4OR9A 4H1YP 1MF8A 3PSNA 4Q7FA 1XM7A 1IT6A 2Z72A 4ORCA 2HYPA 4V0WA 2NYMC 3DW8C 4G9JA 3T1IA 3ZTVA 3QFMA 3RL3A 2NYLC 1HPUA 1S8EA 4J6OA 2WDDA 2R17A 3HVQA
chains in the Genus database with same CATH topology
2NXFA 4FCXA 2WDEA 3D03A 3ZU0A 4V0XA 2BCDA 2YVTA 4IYPC 2QFRA 4FBQA 5INBA 3RQZA 4NZVA 4O5GA 4H2BA 4ZVZA 4XPNA 3LL8A 5GTUA 1U32A 3DSCA 4V0VA 1OIEA 2Z06A 3CK2A 3E7AA 3KBPA 3K7VC 4KKZA 1HO5A 4F0ZA 4O4KA 2DFJA 4WWLA 1V73A 4MOYA 3H64A 3IVDA 5J28A 4LACC 5DNYA 1USHA 3EGHA 2BDXA 3P71C 4JA9A 1HP1A 1W24A 2ZO9B 2P6BA 3C9FA 3H60A 5JPFA 3AV0A 2GJUA 5C1VA 4O24A 1TCOA 3AUZA 3H61A 4ZX2A 4DSYA 4H1SA 1WAO1 4I5LC 5IOHA 3H66A 2DXLA 5EQVA 1S70A 3ICFA 4TUGA 3PSOA 4H2GA 2HYOA 3E0JA 1G5BA 3RL4A 3DSDA 5HPEA 4DT2A 3E7BA 1S95A 5F3WA 4YKEA 3H67A 2CV9A 2NPPC 2WDCA 4UT2A 4I5NC 1UTEA 3V4YA 1M63A 2QFPA 3C5WC 2HY1A 2KKNA 3QFOA 4ORBA 1OI8A 4UT3B 4HD0A 4H2IA 4IL1A 3QFNA 2IAEC 3IVEA 4KBPA 3IB8A 1S3MA 3FLOA 2AHDA 2O8GA 1S3NA 3FGAC 1QHWA 1T71A 5JJTA 1QFCA 5JPEA 4MP0A 1NNWA 3JYFA 3QFKA 4ORAA 4B2OA 1SU1A 1T70A 4JA7A 1XZWA 2XMOA 1WARA 4FBKA 3GVEA 3RL5A 2ZBMA 3THNA 2YEQA 3H62B 4LU9A 4LTYA 3TGHA 4M0VA 1OIDA 4UT3A 2O8AA 2IE4C 2WDFA 3N5UA 4TUIA 2JOGA 4MOVA 3THOB 1Z2WA 1Z2XA 4UWQA 1KBPA 2IE3C 1JK7A 1FJMA 2A22A 4DHLA 1II7A 2QJCA 1AUIA 1S3LA 3H63A 1UF3A 2DXNA 3H68A 2USHA 3H69A 4H2FA 2BQ8X 2ZOAA 3QG5C 5B8IA 3K7WC 3IB7A 4FBWA 4O43A 3EGGA 2Z1AA 2Q8UA 4OR9A 4H1YP 1MF8A 3PSNA 4Q7FA 1XM7A 1IT6A 2Z72A 4ORCA 2HYPA 4V0WA 2NYMC 3DW8C 4G9JA 3T1IA 3ZTVA 3QFMA 3RL3A 2NYLC 1HPUA 1S8EA 4J6OA 2WDDA 2R17A 3HVQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NXF A;  4FCX A;  2WDE A;  3ZU0 A;  4V0X A;  2BCD A;  2YVT A;  4IYP C;  2QFR A;  4FBQ A;  5INB A;  3RQZ A;  4NZV A;  4O5G A;  4H2B A;  4ZVZ A;  4XPN A;  3LL8 A;  5GTU A;  1U32 A;  3DSC A;  4V0V A;  1OIE A;  2Z06 A;  3CK2 A;  3E7A A;  3KBP A;  3K7V C;  4KKZ A;  1HO5 A;  4F0Z A;  4O4K A;  2DFJ A;  4WWL A;  1V73 A;  4MOY A;  3H64 A;  3IVD A;  5J28 A;  4LAC C;  5DNY A;  1USH A;  3EGH A;  2BDX A;  3P71 C;  4JA9 A;  1HP1 A;  1W24 A;  2P6B A;  3C9F A;  3H60 A;  5JPF A;  3AV0 A;  2GJU A;  5C1V A;  4O24 A;  1TCO A;  3AUZ A;  3H61 A;  4ZX2 A;  4DSY A;  4H1S A;  1WAO 1;  4I5L C;  5IOH A;  3H66 A;  5EQV A;  1S70 A;  3ICF A;  4TUG A;  3PSO A;  4H2G A;  2HYO A;  1G5B A;  3RL4 A;  3DSD A;  5HPE A;  4DT2 A;  3E7B A;  1S95 A;  5F3W A;  4YKE A;  3H67 A;  2CV9 A;  2NPP C;  2WDC A;  4UT2 A;  4I5N C;  1UTE A;  3V4Y A;  1M63 A;  2QFP A;  3C5W C;  2HY1 A;  2KKN A;  3QFO A;  4ORB A;  1OI8 A;  4UT3 B;  4HD0 A;  4H2I A;  4IL1 A;  3QFN A;  2IAE C;  3IVE A;  4KBP A;  3IB8 A;  1S3M A;  2AHD A;  2O8G A;  1S3N A;  3FGA C;  1QHW A;  1T71 A;  5JJT A;  1QFC A;  5JPE A;  4MP0 A;  1NNW A;  3JYF A;  3QFK A;  4ORA A;  4B2O A;  1SU1 A;  1T70 A;  4JA7 A;  1XZW A;  2XMO A;  1WAR A;  4FBK A;  3GVE A;  3RL5 A;  2ZBM A;  3THN A;  3H62 B;  4LU9 A;  4LTY A;  3TGH A;  4M0V A;  1OID A;  4UT3 A;  2O8A A;  2IE4 C;  2WDF A;  3N5U A;  4TUI A;  2JOG A;  4MOV A;  3THO B;  1Z2W A;  1Z2X A;  4UWQ A;  1KBP A;  2IE3 C;  1JK7 A;  1FJM A;  2A22 A;  4DHL A;  1II7 A;  2QJC A;  1AUI A;  1S3L A;  3H63 A;  1UF3 A;  3H68 A;  3H69 A;  2USH A;  4H2F A;  2BQ8 X;  3QG5 C;  5B8I A;  3K7W C;  3IB7 A;  4FBW A;  4O43 A;  3EGG A;  2Z1A A;  2Q8U A;  4OR9 A;  4H1Y P;  1MF8 A;  3PSN A;  4Q7F A;  1XM7 A;  1IT6 A;  2Z72 A;  4ORC A;  2HYP A;  4V0W A;  2NYM C;  3DW8 C;  4G9J A;  3T1I A;  3ZTV A;  3QFM A;  3RL3 A;  2NYL C;  1HPU A;  1S8E A;  4J6O A;  2WDD A;  2R17 A;  3HVQ A; 
#chains in the Genus database with same CATH topology
 2NXF A;  4FCX A;  2WDE A;  3D03 A;  3ZU0 A;  4V0X A;  2BCD A;  2YVT A;  4IYP C;  2QFR A;  4FBQ A;  5INB A;  3RQZ A;  4NZV A;  4O5G A;  4H2B A;  4ZVZ A;  4XPN A;  3LL8 A;  5GTU A;  1U32 A;  3DSC A;  4V0V A;  1OIE A;  2Z06 A;  3CK2 A;  3E7A A;  3KBP A;  3K7V C;  4KKZ A;  1HO5 A;  4F0Z A;  4O4K A;  2DFJ A;  4WWL A;  1V73 A;  4MOY A;  3H64 A;  3IVD A;  5J28 A;  4LAC C;  5DNY A;  1USH A;  3EGH A;  2BDX A;  3P71 C;  4JA9 A;  1HP1 A;  1W24 A;  2ZO9 B;  2P6B A;  3C9F A;  3H60 A;  5JPF A;  3AV0 A;  2GJU A;  5C1V A;  4O24 A;  1TCO A;  3AUZ A;  3H61 A;  4ZX2 A;  4DSY A;  4H1S A;  1WAO 1;  4I5L C;  5IOH A;  3H66 A;  2DXL A;  5EQV A;  1S70 A;  3ICF A;  4TUG A;  3PSO A;  4H2G A;  2HYO A;  3E0J A;  1G5B A;  3RL4 A;  3DSD A;  5HPE A;  4DT2 A;  3E7B A;  1S95 A;  5F3W A;  4YKE A;  3H67 A;  2CV9 A;  2NPP C;  2WDC A;  4UT2 A;  4I5N C;  1UTE A;  3V4Y A;  1M63 A;  2QFP A;  3C5W C;  2HY1 A;  2KKN A;  3QFO A;  4ORB A;  1OI8 A;  4UT3 B;  4HD0 A;  4H2I A;  4IL1 A;  3QFN A;  2IAE C;  3IVE A;  4KBP A;  3IB8 A;  1S3M A;  3FLO A;  2AHD A;  2O8G A;  1S3N A;  3FGA C;  1QHW A;  1T71 A;  5JJT A;  1QFC A;  5JPE A;  4MP0 A;  1NNW A;  3JYF A;  3QFK A;  4ORA A;  4B2O A;  1SU1 A;  1T70 A;  4JA7 A;  1XZW A;  2XMO A;  1WAR A;  4FBK A;  3GVE A;  3RL5 A;  2ZBM A;  3THN A;  2YEQ A;  3H62 B;  4LU9 A;  4LTY A;  3TGH A;  4M0V A;  1OID A;  4UT3 A;  2O8A A;  2IE4 C;  2WDF A;  3N5U A;  4TUI A;  2JOG A;  4MOV A;  3THO B;  1Z2W A;  1Z2X A;  4UWQ A;  1KBP A;  2IE3 C;  1JK7 A;  1FJM A;  2A22 A;  4DHL A;  1II7 A;  2QJC A;  1AUI A;  1S3L A;  3H63 A;  1UF3 A;  2DXN A;  3H68 A;  2USH A;  3H69 A;  4H2F A;  2BQ8 X;  2ZOA A;  3QG5 C;  5B8I A;  3K7W C;  3IB7 A;  4FBW A;  4O43 A;  3EGG A;  2Z1A A;  2Q8U A;  4OR9 A;  4H1Y P;  1MF8 A;  3PSN A;  4Q7F A;  1XM7 A;  1IT6 A;  2Z72 A;  4ORC A;  2HYP A;  4V0W A;  2NYM C;  3DW8 C;  4G9J A;  3T1I A;  3ZTV A;  3QFM A;  3RL3 A;  2NYL C;  1HPU A;  1S8E A;  4J6O A;  2WDD A;  2R17 A;  3HVQ A; 
#chains in the Genus database with same CATH homology
 2NXF A;  4FCX A;  2WDE A;  3D03 A;  3ZU0 A;  4V0X A;  2BCD A;  2YVT A;  4IYP C;  2QFR A;  4FBQ A;  5INB A;  3RQZ A;  4NZV A;  4O5G A;  4H2B A;  4ZVZ A;  4XPN A;  3LL8 A;  5GTU A;  1U32 A;  3DSC A;  4V0V A;  1OIE A;  2Z06 A;  3CK2 A;  3E7A A;  3KBP A;  3K7V C;  4KKZ A;  1HO5 A;  4F0Z A;  4O4K A;  2DFJ A;  4WWL A;  1V73 A;  4MOY A;  3H64 A;  3IVD A;  5J28 A;  4LAC C;  5DNY A;  1USH A;  3EGH A;  2BDX A;  3P71 C;  4JA9 A;  1HP1 A;  1W24 A;  2ZO9 B;  2P6B A;  3C9F A;  3H60 A;  5JPF A;  3AV0 A;  2GJU A;  5C1V A;  4O24 A;  1TCO A;  3AUZ A;  3H61 A;  4ZX2 A;  4DSY A;  4H1S A;  1WAO 1;  4I5L C;  5IOH A;  3H66 A;  2DXL A;  5EQV A;  1S70 A;  3ICF A;  4TUG A;  3PSO A;  4H2G A;  2HYO A;  3E0J A;  1G5B A;  3RL4 A;  3DSD A;  5HPE A;  4DT2 A;  3E7B A;  1S95 A;  5F3W A;  4YKE A;  3H67 A;  2CV9 A;  2NPP C;  2WDC A;  4UT2 A;  4I5N C;  1UTE A;  3V4Y A;  1M63 A;  2QFP A;  3C5W C;  2HY1 A;  2KKN A;  3QFO A;  4ORB A;  1OI8 A;  4UT3 B;  4HD0 A;  4H2I A;  4IL1 A;  3QFN A;  2IAE C;  3IVE A;  4KBP A;  3IB8 A;  1S3M A;  3FLO A;  2AHD A;  2O8G A;  1S3N A;  3FGA C;  1QHW A;  1T71 A;  5JJT A;  1QFC A;  5JPE A;  4MP0 A;  1NNW A;  3JYF A;  3QFK A;  4ORA A;  4B2O A;  1SU1 A;  1T70 A;  4JA7 A;  1XZW A;  2XMO A;  1WAR A;  4FBK A;  3GVE A;  3RL5 A;  2ZBM A;  3THN A;  2YEQ A;  3H62 B;  4LU9 A;  4LTY A;  3TGH A;  4M0V A;  1OID A;  4UT3 A;  2O8A A;  2IE4 C;  2WDF A;  3N5U A;  4TUI A;  2JOG A;  4MOV A;  3THO B;  1Z2W A;  1Z2X A;  4UWQ A;  1KBP A;  2IE3 C;  1JK7 A;  1FJM A;  2A22 A;  4DHL A;  1II7 A;  2QJC A;  1AUI A;  1S3L A;  3H63 A;  1UF3 A;  2DXN A;  3H68 A;  2USH A;  3H69 A;  4H2F A;  2BQ8 X;  2ZOA A;  3QG5 C;  5B8I A;  3K7W C;  3IB7 A;  4FBW A;  4O43 A;  3EGG A;  2Z1A A;  2Q8U A;  4OR9 A;  4H1Y P;  1MF8 A;  3PSN A;  4Q7F A;  1XM7 A;  1IT6 A;  2Z72 A;  4ORC A;  2HYP A;  4V0W A;  2NYM C;  3DW8 C;  4G9J A;  3T1I A;  3ZTV A;  3QFM A;  3RL3 A;  2NYL C;  1HPU A;  1S8E A;  4J6O A;  2WDD A;  2R17 A;  3HVQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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