3RL3A

Rat metallophosphodiesterase mpped2
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
281
structure length
276
Chain Sequence
VTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
pubmed doi rcsb
molecule keywords Metallophosphoesterase MPPED2
molecule tags Hydrolase
source organism Rattus norvegicus
total genus 86
structure length 276
sequence length 281
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3rl3A00
2QJCA 4ORBA 1XZWA 5HPEA 4ORCA 1HPUA 1OIEA 4TUGA 4HD0A 3LL8A 2WDFA 1M63A 2IE3C 2YVTA 3DSDA 1FJMA 4H1YP 3AV0A 4LU9A 4ZX2A 1T70A 2WDCA 4IL1A 2NPPC 4DT2A 1KBPA 4FBQA 5J28A 2WDDA 2KKNA 2Q8UA 2BQ8X 1WAO1 4M0VA 2WDEA 2NYMC 4O24A 4IYPC 1TCOA 2IE4C 4I5LC 3T1IA 3HVQA 3K7VC 1XM7A 3H64A 1WARA 4J6OA 4TUIA 1II7A 3RL4A 4DHLA 2USHA 3THNA 3QFKA 3IVEA 3IB7A 4LACC 1S3LA 1USHA 4WWLA 3QG5C 3RQZA 5DNYA 3RL3A 5JPFA 3H61A 4B2OA 2HYOA 3RL5A 3IVDA 3H63A 4DSYA 3QFNA 4NZVA 5JJTA 1S8EA 2R17A 3H60A 4MP0A 2QFPA 2NYLC 4UT3B 3AUZA 5IOHA 4O4KA 4XPNA 2HYPA 2NXFA 3JYFA 3THOB 5F3WA 4KKZA 4O5GA 2ZBMA 2AHDA 2BDXA 3PSNA 1V73A 3FGAC 4OR9A 2CV9A 3GVEA 4KBPA 4H2IA 4H2FA 4MOYA 1QHWA 3DW8C 3C5WC 2JOGA 3P71C 4UT2A 3ZU0A 3EGGA 2Z06A 1Z2WA 2Z72A 2HY1A 2BCDA 3KBPA 1U32A 4FCXA 3E7BA 3QFMA 1OI8A 3IB8A 3H66A 1OIDA 5INBA 4I5NC 4MOVA 3N5UA 3PSOA 5C1VA 4ORAA 1HO5A 3H67A 3QFOA 4V0WA 4UT3A 2QFRA 1MF8A 4H2BA 3H62B 5JPEA 1T71A 1NNWA 4H1SA 4V0VA 5GTUA 5B8IA 1W24A 4ZVZA 1QFCA 2XMOA 2A22A 4LTYA 3H69A 1S3NA 1IT6A 1JK7A 4H2GA 3EGHA 3TGHA 3CK2A 4JA7A 3C9FA 4FBWA 1S3MA 4JA9A 2P6BA 1HP1A 1Z2XA 4V0XA 1SU1A 1AUIA 2GJUA 3K7WC 4F0ZA 4G9JA 3H68A 4Q7FA 4UWQA 3ZTVA 1S95A 1UF3A 3E7AA 4YKEA 3DSCA 4FBKA 1UTEA 2IAEC 2O8GA 2Z1AA 4O43A 5EQVA 3V4YA 2O8AA 2DFJA 3ICFA 1G5BA 1S70A
chains in the Genus database with same CATH superfamily
2QJCA 4ORBA 1XZWA 5HPEA 4ORCA 1HPUA 1OIEA 4TUGA 2YEQA 4HD0A 3LL8A 2WDFA 1M63A 2IE3C 2YVTA 3DSDA 1FJMA 4H1YP 3AV0A 4LU9A 4ZX2A 1T70A 2WDCA 4IL1A 2NPPC 4DT2A 1KBPA 4FBQA 5J28A 2WDDA 2DXLA 2KKNA 2Q8UA 2BQ8X 1WAO1 4M0VA 2WDEA 2NYMC 4O24A 4IYPC 1TCOA 2IE4C 4I5LC 3T1IA 3HVQA 3K7VC 1XM7A 3H64A 1WARA 4J6OA 4TUIA 1II7A 3RL4A 4DHLA 2USHA 3THNA 3QFKA 3IVEA 3IB7A 4LACC 1S3LA 1USHA 4WWLA 3QG5C 3RQZA 5DNYA 3RL3A 5JPFA 3H61A 4B2OA 2HYOA 2ZOAA 3FLOA 3IVDA 3RL5A 3H63A 4DSYA 3QFNA 4NZVA 5JJTA 1S8EA 2R17A 3H60A 4MP0A 2QFPA 2NYLC 4UT3B 3AUZA 5IOHA 4O4KA 4XPNA 2HYPA 2NXFA 3JYFA 3THOB 5F3WA 4KKZA 4O5GA 2ZBMA 2AHDA 2BDXA 3PSNA 1V73A 3FGAC 4OR9A 2CV9A 3GVEA 4KBPA 4H2IA 4H2FA 4MOYA 1QHWA 3DW8C 3C5WC 2JOGA 3P71C 4UT2A 3ZU0A 3EGGA 2Z06A 1Z2WA 2Z72A 2HY1A 2BCDA 3KBPA 2ZO9B 1U32A 4FCXA 3E7BA 3QFMA 3D03A 1OI8A 3IB8A 3H66A 1OIDA 5INBA 4I5NC 4MOVA 3N5UA 3PSOA 5C1VA 4ORAA 1HO5A 3H67A 3QFOA 4V0WA 4UT3A 2QFRA 1MF8A 4H2BA 3H62B 5JPEA 1T71A 1NNWA 4H1SA 4V0VA 5GTUA 5B8IA 1W24A 2DXNA 4ZVZA 1QFCA 2XMOA 2A22A 3E0JA 4LTYA 3H69A 1S3NA 1IT6A 1JK7A 4H2GA 3EGHA 3TGHA 3CK2A 4JA7A 3C9FA 4FBWA 1S3MA 4JA9A 2P6BA 1HP1A 1Z2XA 4V0XA 1SU1A 1AUIA 2GJUA 3K7WC 4F0ZA 4G9JA 3H68A 4Q7FA 4UWQA 3ZTVA 1S95A 1UF3A 3E7AA 4YKEA 3DSCA 4FBKA 1UTEA 2IAEC 2O8GA 2Z1AA 4O43A 5EQVA 3V4YA 2O8AA 2DFJA 3ICFA 1G5BA 1S70A
chains in the Genus database with same CATH topology
2QJCA 4ORBA 1XZWA 5HPEA 4ORCA 1HPUA 1OIEA 4TUGA 2YEQA 4HD0A 3LL8A 2WDFA 1M63A 2IE3C 2YVTA 3DSDA 1FJMA 4H1YP 3AV0A 4LU9A 4ZX2A 1T70A 2WDCA 4IL1A 2NPPC 4DT2A 1KBPA 4FBQA 5J28A 2WDDA 2DXLA 2KKNA 2Q8UA 2BQ8X 1WAO1 4M0VA 2WDEA 2NYMC 4O24A 4IYPC 1TCOA 2IE4C 4I5LC 3T1IA 3HVQA 3K7VC 1XM7A 3H64A 1WARA 4J6OA 4TUIA 1II7A 3RL4A 4DHLA 2USHA 3THNA 3QFKA 3IVEA 3IB7A 4LACC 1S3LA 1USHA 4WWLA 3QG5C 3RQZA 5DNYA 3RL3A 5JPFA 3H61A 4B2OA 2HYOA 2ZOAA 3FLOA 3IVDA 3RL5A 3H63A 4DSYA 3QFNA 4NZVA 5JJTA 1S8EA 2R17A 3H60A 4MP0A 2QFPA 2NYLC 4UT3B 3AUZA 5IOHA 4O4KA 4XPNA 2HYPA 2NXFA 3JYFA 3THOB 5F3WA 4KKZA 4O5GA 2ZBMA 2AHDA 2BDXA 3PSNA 1V73A 3FGAC 4OR9A 2CV9A 3GVEA 4KBPA 4H2IA 4H2FA 4MOYA 1QHWA 3DW8C 3C5WC 2JOGA 3P71C 4UT2A 3ZU0A 3EGGA 2Z06A 1Z2WA 2Z72A 2HY1A 2BCDA 3KBPA 2ZO9B 1U32A 4FCXA 3E7BA 3QFMA 3D03A 1OI8A 3IB8A 3H66A 1OIDA 5INBA 4I5NC 4MOVA 3N5UA 3PSOA 5C1VA 4ORAA 1HO5A 3H67A 3QFOA 4V0WA 4UT3A 2QFRA 1MF8A 4H2BA 3H62B 5JPEA 1T71A 1NNWA 4H1SA 4V0VA 5GTUA 5B8IA 1W24A 2DXNA 4ZVZA 1QFCA 2XMOA 2A22A 3E0JA 4LTYA 3H69A 1S3NA 1IT6A 1JK7A 4H2GA 3EGHA 3TGHA 3CK2A 4JA7A 3C9FA 4FBWA 1S3MA 4JA9A 2P6BA 1HP1A 1Z2XA 4V0XA 1SU1A 1AUIA 2GJUA 3K7WC 4F0ZA 4G9JA 3H68A 4Q7FA 4UWQA 3ZTVA 1S95A 1UF3A 3E7AA 4YKEA 3DSCA 4FBKA 1UTEA 2IAEC 2O8GA 2Z1AA 4O43A 5EQVA 3V4YA 2O8AA 2DFJA 3ICFA 1G5BA 1S70A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2QJC A;  4ORB A;  1XZW A;  5HPE A;  4ORC A;  1HPU A;  1OIE A;  4TUG A;  4HD0 A;  3LL8 A;  2WDF A;  1M63 A;  2IE3 C;  2YVT A;  3DSD A;  1FJM A;  4H1Y P;  3AV0 A;  4LU9 A;  4ZX2 A;  1T70 A;  2WDC A;  4IL1 A;  2NPP C;  4DT2 A;  1KBP A;  4FBQ A;  5J28 A;  2WDD A;  2KKN A;  2Q8U A;  2BQ8 X;  1WAO 1;  4M0V A;  2WDE A;  2NYM C;  4O24 A;  4IYP C;  1TCO A;  2IE4 C;  4I5L C;  3T1I A;  3HVQ A;  3K7V C;  1XM7 A;  3H64 A;  1WAR A;  4J6O A;  4TUI A;  1II7 A;  3RL4 A;  4DHL A;  2USH A;  3THN A;  3QFK A;  3IVE A;  3IB7 A;  4LAC C;  1S3L A;  1USH A;  4WWL A;  3QG5 C;  3RQZ A;  5DNY A;  3RL3 A;  5JPF A;  3H61 A;  4B2O A;  2HYO A;  3RL5 A;  3IVD A;  3H63 A;  4DSY A;  3QFN A;  4NZV A;  5JJT A;  1S8E A;  2R17 A;  3H60 A;  4MP0 A;  2QFP A;  2NYL C;  4UT3 B;  3AUZ A;  5IOH A;  4O4K A;  4XPN A;  2HYP A;  2NXF A;  3JYF A;  3THO B;  5F3W A;  4KKZ A;  4O5G A;  2ZBM A;  2AHD A;  2BDX A;  3PSN A;  1V73 A;  3FGA C;  4OR9 A;  2CV9 A;  3GVE A;  4KBP A;  4H2I A;  4H2F A;  4MOY A;  1QHW A;  3DW8 C;  3C5W C;  2JOG A;  3P71 C;  4UT2 A;  3ZU0 A;  3EGG A;  2Z06 A;  1Z2W A;  2Z72 A;  2HY1 A;  2BCD A;  3KBP A;  1U32 A;  4FCX A;  3E7B A;  3QFM A;  1OI8 A;  3IB8 A;  3H66 A;  1OID A;  5INB A;  4I5N C;  4MOV A;  3N5U A;  3PSO A;  5C1V A;  4ORA A;  1HO5 A;  3H67 A;  3QFO A;  4V0W A;  4UT3 A;  2QFR A;  1MF8 A;  4H2B A;  3H62 B;  5JPE A;  1T71 A;  1NNW A;  4H1S A;  4V0V A;  5GTU A;  5B8I A;  1W24 A;  4ZVZ A;  1QFC A;  2XMO A;  2A22 A;  4LTY A;  3H69 A;  1S3N A;  1IT6 A;  1JK7 A;  4H2G A;  3EGH A;  3TGH A;  3CK2 A;  4JA7 A;  3C9F A;  4FBW A;  1S3M A;  4JA9 A;  2P6B A;  1HP1 A;  1Z2X A;  4V0X A;  1SU1 A;  1AUI A;  2GJU A;  3K7W C;  4F0Z A;  4G9J A;  3H68 A;  4Q7F A;  4UWQ A;  3ZTV A;  1S95 A;  1UF3 A;  3E7A A;  4YKE A;  3DSC A;  4FBK A;  1UTE A;  2IAE C;  2O8G A;  2Z1A A;  4O43 A;  5EQV A;  3V4Y A;  2O8A A;  2DFJ A;  3ICF A;  1G5B A;  1S70 A; 
#chains in the Genus database with same CATH topology
 2QJC A;  4ORB A;  1XZW A;  5HPE A;  4ORC A;  1HPU A;  1OIE A;  4TUG A;  2YEQ A;  4HD0 A;  3LL8 A;  2WDF A;  1M63 A;  2IE3 C;  2YVT A;  3DSD A;  1FJM A;  4H1Y P;  3AV0 A;  4LU9 A;  4ZX2 A;  1T70 A;  2WDC A;  4IL1 A;  2NPP C;  4DT2 A;  1KBP A;  4FBQ A;  5J28 A;  2WDD A;  2DXL A;  2KKN A;  2Q8U A;  2BQ8 X;  1WAO 1;  4M0V A;  2WDE A;  2NYM C;  4O24 A;  4IYP C;  1TCO A;  2IE4 C;  4I5L C;  3T1I A;  3HVQ A;  3K7V C;  1XM7 A;  3H64 A;  1WAR A;  4J6O A;  4TUI A;  1II7 A;  3RL4 A;  4DHL A;  2USH A;  3THN A;  3QFK A;  3IVE A;  3IB7 A;  4LAC C;  1S3L A;  1USH A;  4WWL A;  3QG5 C;  3RQZ A;  5DNY A;  3RL3 A;  5JPF A;  3H61 A;  4B2O A;  2HYO A;  2ZOA A;  3FLO A;  3IVD A;  3RL5 A;  3H63 A;  4DSY A;  3QFN A;  4NZV A;  5JJT A;  1S8E A;  2R17 A;  3H60 A;  4MP0 A;  2QFP A;  2NYL C;  4UT3 B;  3AUZ A;  5IOH A;  4O4K A;  4XPN A;  2HYP A;  2NXF A;  3JYF A;  3THO B;  5F3W A;  4KKZ A;  4O5G A;  2ZBM A;  2AHD A;  2BDX A;  3PSN A;  1V73 A;  3FGA C;  4OR9 A;  2CV9 A;  3GVE A;  4KBP A;  4H2I A;  4H2F A;  4MOY A;  1QHW A;  3DW8 C;  3C5W C;  2JOG A;  3P71 C;  4UT2 A;  3ZU0 A;  3EGG A;  2Z06 A;  1Z2W A;  2Z72 A;  2HY1 A;  2BCD A;  3KBP A;  2ZO9 B;  1U32 A;  4FCX A;  3E7B A;  3QFM A;  3D03 A;  1OI8 A;  3IB8 A;  3H66 A;  1OID A;  5INB A;  4I5N C;  4MOV A;  3N5U A;  3PSO A;  5C1V A;  4ORA A;  1HO5 A;  3H67 A;  3QFO A;  4V0W A;  4UT3 A;  2QFR A;  1MF8 A;  4H2B A;  3H62 B;  5JPE A;  1T71 A;  1NNW A;  4H1S A;  4V0V A;  5GTU A;  5B8I A;  1W24 A;  2DXN A;  4ZVZ A;  1QFC A;  2XMO A;  2A22 A;  3E0J A;  4LTY A;  3H69 A;  1S3N A;  1IT6 A;  1JK7 A;  4H2G A;  3EGH A;  3TGH A;  3CK2 A;  4JA7 A;  3C9F A;  4FBW A;  1S3M A;  4JA9 A;  2P6B A;  1HP1 A;  1Z2X A;  4V0X A;  1SU1 A;  1AUI A;  2GJU A;  3K7W C;  4F0Z A;  4G9J A;  3H68 A;  4Q7F A;  4UWQ A;  3ZTV A;  1S95 A;  1UF3 A;  3E7A A;  4YKE A;  3DSC A;  4FBK A;  1UTE A;  2IAE C;  2O8G A;  2Z1A A;  4O43 A;  5EQV A;  3V4Y A;  2O8A A;  2DFJ A;  3ICF A;  1G5B A;  1S70 A; 
#chains in the Genus database with same CATH homology
 2QJC A;  4ORB A;  1XZW A;  5HPE A;  4ORC A;  1HPU A;  1OIE A;  4TUG A;  2YEQ A;  4HD0 A;  3LL8 A;  2WDF A;  1M63 A;  2IE3 C;  2YVT A;  3DSD A;  1FJM A;  4H1Y P;  3AV0 A;  4LU9 A;  4ZX2 A;  1T70 A;  2WDC A;  4IL1 A;  2NPP C;  4DT2 A;  1KBP A;  4FBQ A;  5J28 A;  2WDD A;  2DXL A;  2KKN A;  2Q8U A;  2BQ8 X;  1WAO 1;  4M0V A;  2WDE A;  2NYM C;  4O24 A;  4IYP C;  1TCO A;  2IE4 C;  4I5L C;  3T1I A;  3HVQ A;  3K7V C;  1XM7 A;  3H64 A;  1WAR A;  4J6O A;  4TUI A;  1II7 A;  3RL4 A;  4DHL A;  2USH A;  3THN A;  3QFK A;  3IVE A;  3IB7 A;  4LAC C;  1S3L A;  1USH A;  4WWL A;  3QG5 C;  3RQZ A;  5DNY A;  3RL3 A;  5JPF A;  3H61 A;  4B2O A;  2HYO A;  2ZOA A;  3FLO A;  3IVD A;  3RL5 A;  3H63 A;  4DSY A;  3QFN A;  4NZV A;  5JJT A;  1S8E A;  2R17 A;  3H60 A;  4MP0 A;  2QFP A;  2NYL C;  4UT3 B;  3AUZ A;  5IOH A;  4O4K A;  4XPN A;  2HYP A;  2NXF A;  3JYF A;  3THO B;  5F3W A;  4KKZ A;  4O5G A;  2ZBM A;  2AHD A;  2BDX A;  3PSN A;  1V73 A;  3FGA C;  4OR9 A;  2CV9 A;  3GVE A;  4KBP A;  4H2I A;  4H2F A;  4MOY A;  1QHW A;  3DW8 C;  3C5W C;  2JOG A;  3P71 C;  4UT2 A;  3ZU0 A;  3EGG A;  2Z06 A;  1Z2W A;  2Z72 A;  2HY1 A;  2BCD A;  3KBP A;  2ZO9 B;  1U32 A;  4FCX A;  3E7B A;  3QFM A;  3D03 A;  1OI8 A;  3IB8 A;  3H66 A;  1OID A;  5INB A;  4I5N C;  4MOV A;  3N5U A;  3PSO A;  5C1V A;  4ORA A;  1HO5 A;  3H67 A;  3QFO A;  4V0W A;  4UT3 A;  2QFR A;  1MF8 A;  4H2B A;  3H62 B;  5JPE A;  1T71 A;  1NNW A;  4H1S A;  4V0V A;  5GTU A;  5B8I A;  1W24 A;  2DXN A;  4ZVZ A;  1QFC A;  2XMO A;  2A22 A;  3E0J A;  4LTY A;  3H69 A;  1S3N A;  1IT6 A;  1JK7 A;  4H2G A;  3EGH A;  3TGH A;  3CK2 A;  4JA7 A;  3C9F A;  4FBW A;  1S3M A;  4JA9 A;  2P6B A;  1HP1 A;  1Z2X A;  4V0X A;  1SU1 A;  1AUI A;  2GJU A;  3K7W C;  4F0Z A;  4G9J A;  3H68 A;  4Q7F A;  4UWQ A;  3ZTV A;  1S95 A;  1UF3 A;  3E7A A;  4YKE A;  3DSC A;  4FBK A;  1UTE A;  2IAE C;  2O8G A;  2Z1A A;  4O43 A;  5EQV A;  3V4Y A;  2O8A A;  2DFJ A;  3ICF A;  1G5B A;  1S70 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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