3RL3A

Rat metallophosphodiesterase mpped2
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
281
structure length
276
Chain Sequence
VTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Metallophosphoesterase MPPED2
publication title Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
pubmed doi rcsb
source organism Rattus norvegicus
total genus 86
structure length 276
sequence length 281
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3rl3A00
3H61A 4LU9A 3H68A 1HO5A 2ZBMA 3DW8C 3FGAC 3ICFA 4I5LC 4DT2A 3LL8A 3THOB 1MF8A 4NZVA 4ORCA 1QHWA 4UWQA 1S95A 3ZU0A 2BCDA 5JJTA 4H2BA 4UT3A 2IE4C 4FBWA 5IOHA 3T1IA 4HD0A 4KKZA 1Z2WA 3H66A 3RL5A 2Z72A 1WAO1 4Q7FA 4J6OA 2XMOA 4LACC 4IYPC 3RL4A 1U32A 3N5UA 3QFMA 5HPEA 3H67A 3QG5C 3AUZA 3RQZA 5C1VA 4FBQA 2GJUA 2Z1AA 4TUGA 1XZWA 2JOGA 3AV0A 4LTYA 4G9JA 4H2FA 4YKEA 3QFNA 1FJMA 3PSNA 2QJCA 3C5WC 2IAEC 2BDXA 5F3WA 5EQVA 3H69A 4IL1A 2BQ8X 4UT2A 2CV9A 1Z2XA 3H64A 4FCXA 4O4KA 1JK7A 4MOVA 2QFPA 2Z06A 3H60A 3E7AA 3QFKA 4V0VA 2Q8UA 2HYOA 3CK2A 1NNWA 2A22A 1M63A 4H2IA 3EGHA 4M0VA 4JA9A 1S3MA 4ZX2A 1S3LA 2USHA 3KBPA 2NYLC 1OIDA 4TUIA 5J28A 4UT3B 3DSDA 5JPFA 2P6BA 3GVEA 2KKNA 2NPPC 2WDEA 3H63A 4F0ZA 5GTUA 3RL3A 3IB8A 1S3NA 2NXFA 4O43A 4MP0A 1SU1A 1WARA 2HY1A 4XPNA 4ORAA 4ZVZA 3IVDA 1TCOA 2QFRA 4V0XA 3IVEA 4DSYA 5INBA 1T70A 1V73A 4I5NC 3K7WC 1KBPA 4WWLA 1G5BA 4KBPA 4O24A 1OI8A 1UTEA 1W24A 4H2GA 5DNYA 4O5GA 4B2OA 4H1SA 3THNA 3ZTVA 1XM7A 2DFJA 1IT6A 3IB7A 4FBKA 3PSOA 3TGHA 3QFOA 4DHLA 2YVTA 4MOYA 1HP1A 2HYPA 4ORBA 2WDCA 3V4YA 5B8IA 1UF3A 1S8EA 4JA7A 1USHA 1QFCA 3HVQA 4V0WA 3H62B 2NYMC 1S70A 2WDFA 2O8AA 2O8GA 1T71A 3C9FA 1AUIA 1HPUA 2IE3C 2R17A 2WDDA 3JYFA 4H1YP 4OR9A 1OIEA 3E7BA 5JPEA 3P71C 2AHDA 3EGGA 3DSCA 3K7VC 1II7A
chains in the Genus database with same CATH superfamily
3H61A 4LU9A 3H68A 1HO5A 2ZBMA 3DW8C 3FGAC 3ICFA 4I5LC 4DT2A 3LL8A 3THOB 1MF8A 4NZVA 4ORCA 1QHWA 4UWQA 1S95A 3ZU0A 2BCDA 2DXLA 4H2BA 5JJTA 4UT3A 2IE4C 4FBWA 2DXNA 3T1IA 5IOHA 4HD0A 4KKZA 1Z2WA 2YEQA 3H66A 3RL5A 2Z72A 1WAO1 4Q7FA 4J6OA 2XMOA 4LACC 4IYPC 3RL4A 1U32A 3N5UA 3QFMA 5HPEA 3H67A 3QG5C 3AUZA 3RQZA 3FLOA 4FBQA 2GJUA 2Z1AA 5C1VA 1XZWA 2JOGA 4TUGA 3AV0A 4LTYA 4G9JA 4H2FA 4YKEA 3QFNA 1FJMA 3PSNA 2QJCA 3C5WC 2IAEC 2BDXA 5F3WA 5EQVA 3H69A 4IL1A 2BQ8X 4UT2A 2CV9A 1Z2XA 3H64A 4FCXA 4O4KA 1JK7A 4MOVA 2QFPA 2Z06A 3H60A 3E7AA 3QFKA 4V0VA 2Q8UA 2HYOA 3CK2A 1NNWA 2A22A 1M63A 4H2IA 3EGHA 4M0VA 4JA9A 1S3MA 4ZX2A 1S3LA 2USHA 3KBPA 2NYLC 1OIDA 4TUIA 5J28A 4UT3B 3DSDA 5JPFA 2P6BA 3GVEA 2KKNA 2NPPC 2WDEA 3H63A 4F0ZA 5GTUA 3RL3A 3IB8A 1S3NA 2NXFA 4O43A 4MP0A 1SU1A 1WARA 2HY1A 4XPNA 4ORAA 4ZVZA 3IVDA 1TCOA 2QFRA 4V0XA 3IVEA 4DSYA 5INBA 1T70A 2ZO9B 1V73A 4I5NC 3K7WC 1KBPA 4WWLA 1G5BA 4KBPA 4O24A 1OI8A 1UTEA 1W24A 4H2GA 5DNYA 4O5GA 4B2OA 4H1SA 3THNA 3ZTVA 1XM7A 2DFJA 1IT6A 3IB7A 4FBKA 3E0JA 3PSOA 3TGHA 3QFOA 4DHLA 2YVTA 4MOYA 1HP1A 2HYPA 4ORBA 2WDCA 3D03A 3V4YA 5B8IA 1UF3A 1S8EA 4JA7A 1USHA 1QFCA 3HVQA 4V0WA 3H62B 2NYMC 1S70A 2WDFA 2O8AA 2O8GA 1T71A 3C9FA 1AUIA 1HPUA 2IE3C 2R17A 2WDDA 3JYFA 4H1YP 4OR9A 1OIEA 3E7BA 5JPEA 2ZOAA 3P71C 2AHDA 3EGGA 3DSCA 3K7VC 1II7A
chains in the Genus database with same CATH topology
3H61A 4LU9A 3H68A 1HO5A 2ZBMA 3DW8C 3FGAC 3ICFA 4I5LC 4DT2A 3LL8A 3THOB 1MF8A 4NZVA 4ORCA 1QHWA 4UWQA 1S95A 3ZU0A 2BCDA 2DXLA 4H2BA 5JJTA 4UT3A 2IE4C 4FBWA 2DXNA 3T1IA 5IOHA 4HD0A 4KKZA 1Z2WA 2YEQA 3H66A 3RL5A 2Z72A 1WAO1 4Q7FA 4J6OA 2XMOA 4LACC 4IYPC 3RL4A 1U32A 3N5UA 3QFMA 5HPEA 3H67A 3QG5C 3AUZA 3RQZA 3FLOA 4FBQA 2GJUA 2Z1AA 5C1VA 1XZWA 2JOGA 4TUGA 3AV0A 4LTYA 4G9JA 4H2FA 4YKEA 3QFNA 1FJMA 3PSNA 2QJCA 3C5WC 2IAEC 2BDXA 5F3WA 5EQVA 3H69A 4IL1A 2BQ8X 4UT2A 2CV9A 1Z2XA 3H64A 4FCXA 4O4KA 1JK7A 4MOVA 2QFPA 2Z06A 3H60A 3E7AA 3QFKA 4V0VA 2Q8UA 2HYOA 3CK2A 1NNWA 2A22A 1M63A 4H2IA 3EGHA 4M0VA 4JA9A 1S3MA 4ZX2A 1S3LA 2USHA 3KBPA 2NYLC 1OIDA 4TUIA 5J28A 4UT3B 3DSDA 5JPFA 2P6BA 3GVEA 2KKNA 2NPPC 2WDEA 3H63A 4F0ZA 5GTUA 3RL3A 3IB8A 1S3NA 2NXFA 4O43A 4MP0A 1SU1A 1WARA 2HY1A 4XPNA 4ORAA 4ZVZA 3IVDA 1TCOA 2QFRA 4V0XA 3IVEA 4DSYA 5INBA 1T70A 2ZO9B 1V73A 4I5NC 3K7WC 1KBPA 4WWLA 1G5BA 4KBPA 4O24A 1OI8A 1UTEA 1W24A 4H2GA 5DNYA 4O5GA 4B2OA 4H1SA 3THNA 3ZTVA 1XM7A 2DFJA 1IT6A 3IB7A 4FBKA 3E0JA 3PSOA 3TGHA 3QFOA 4DHLA 2YVTA 4MOYA 1HP1A 2HYPA 4ORBA 2WDCA 3D03A 3V4YA 5B8IA 1UF3A 1S8EA 4JA7A 1USHA 1QFCA 3HVQA 4V0WA 3H62B 2NYMC 1S70A 2WDFA 2O8AA 2O8GA 1T71A 3C9FA 1AUIA 1HPUA 2IE3C 2R17A 2WDDA 3JYFA 4H1YP 4OR9A 1OIEA 3E7BA 5JPEA 2ZOAA 3P71C 2AHDA 3EGGA 3DSCA 3K7VC 1II7A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3H61 A;  4LU9 A;  3H68 A;  1HO5 A;  2ZBM A;  3DW8 C;  3FGA C;  3ICF A;  4I5L C;  4DT2 A;  3LL8 A;  3THO B;  1MF8 A;  4NZV A;  4ORC A;  1QHW A;  4UWQ A;  1S95 A;  3ZU0 A;  2BCD A;  5JJT A;  4H2B A;  4UT3 A;  2IE4 C;  4FBW A;  5IOH A;  3T1I A;  4HD0 A;  4KKZ A;  1Z2W A;  3H66 A;  3RL5 A;  2Z72 A;  1WAO 1;  4Q7F A;  4J6O A;  2XMO A;  4LAC C;  4IYP C;  3RL4 A;  1U32 A;  3N5U A;  3QFM A;  5HPE A;  3H67 A;  3QG5 C;  3AUZ A;  3RQZ A;  5C1V A;  4FBQ A;  2GJU A;  2Z1A A;  4TUG A;  1XZW A;  2JOG A;  3AV0 A;  4LTY A;  4G9J A;  4H2F A;  4YKE A;  3QFN A;  1FJM A;  3PSN A;  2QJC A;  3C5W C;  2IAE C;  2BDX A;  5F3W A;  5EQV A;  3H69 A;  4IL1 A;  2BQ8 X;  4UT2 A;  2CV9 A;  1Z2X A;  3H64 A;  4FCX A;  4O4K A;  1JK7 A;  4MOV A;  2QFP A;  2Z06 A;  3H60 A;  3E7A A;  3QFK A;  4V0V A;  2Q8U A;  2HYO A;  3CK2 A;  1NNW A;  2A22 A;  1M63 A;  4H2I A;  3EGH A;  4M0V A;  4JA9 A;  1S3M A;  4ZX2 A;  1S3L A;  2USH A;  3KBP A;  2NYL C;  1OID A;  4TUI A;  5J28 A;  4UT3 B;  3DSD A;  5JPF A;  2P6B A;  3GVE A;  2KKN A;  2NPP C;  2WDE A;  3H63 A;  4F0Z A;  5GTU A;  3RL3 A;  3IB8 A;  1S3N A;  2NXF A;  4O43 A;  4MP0 A;  1SU1 A;  1WAR A;  2HY1 A;  4XPN A;  4ORA A;  4ZVZ A;  3IVD A;  1TCO A;  2QFR A;  4V0X A;  3IVE A;  4DSY A;  5INB A;  1T70 A;  1V73 A;  4I5N C;  3K7W C;  1KBP A;  4WWL A;  1G5B A;  4KBP A;  4O24 A;  1OI8 A;  1UTE A;  1W24 A;  4H2G A;  5DNY A;  4O5G A;  4B2O A;  4H1S A;  3THN A;  3ZTV A;  1XM7 A;  2DFJ A;  1IT6 A;  3IB7 A;  4FBK A;  3PSO A;  3TGH A;  3QFO A;  4DHL A;  2YVT A;  4MOY A;  1HP1 A;  2HYP A;  4ORB A;  2WDC A;  3V4Y A;  5B8I A;  1UF3 A;  1S8E A;  4JA7 A;  1USH A;  1QFC A;  3HVQ A;  4V0W A;  3H62 B;  2NYM C;  1S70 A;  2WDF A;  2O8A A;  2O8G A;  1T71 A;  3C9F A;  1AUI A;  1HPU A;  2IE3 C;  2R17 A;  2WDD A;  3JYF A;  4H1Y P;  4OR9 A;  1OIE A;  3E7B A;  5JPE A;  3P71 C;  2AHD A;  3EGG A;  3DSC A;  3K7V C;  1II7 A; 
#chains in the Genus database with same CATH topology
 3H61 A;  4LU9 A;  3H68 A;  1HO5 A;  2ZBM A;  3DW8 C;  3FGA C;  3ICF A;  4I5L C;  4DT2 A;  3LL8 A;  3THO B;  1MF8 A;  4NZV A;  4ORC A;  1QHW A;  4UWQ A;  1S95 A;  3ZU0 A;  2BCD A;  2DXL A;  4H2B A;  5JJT A;  4UT3 A;  2IE4 C;  4FBW A;  2DXN A;  3T1I A;  5IOH A;  4HD0 A;  4KKZ A;  1Z2W A;  2YEQ A;  3H66 A;  3RL5 A;  2Z72 A;  1WAO 1;  4Q7F A;  4J6O A;  2XMO A;  4LAC C;  4IYP C;  3RL4 A;  1U32 A;  3N5U A;  3QFM A;  5HPE A;  3H67 A;  3QG5 C;  3AUZ A;  3RQZ A;  3FLO A;  4FBQ A;  2GJU A;  2Z1A A;  5C1V A;  1XZW A;  2JOG A;  4TUG A;  3AV0 A;  4LTY A;  4G9J A;  4H2F A;  4YKE A;  3QFN A;  1FJM A;  3PSN A;  2QJC A;  3C5W C;  2IAE C;  2BDX A;  5F3W A;  5EQV A;  3H69 A;  4IL1 A;  2BQ8 X;  4UT2 A;  2CV9 A;  1Z2X A;  3H64 A;  4FCX A;  4O4K A;  1JK7 A;  4MOV A;  2QFP A;  2Z06 A;  3H60 A;  3E7A A;  3QFK A;  4V0V A;  2Q8U A;  2HYO A;  3CK2 A;  1NNW A;  2A22 A;  1M63 A;  4H2I A;  3EGH A;  4M0V A;  4JA9 A;  1S3M A;  4ZX2 A;  1S3L A;  2USH A;  3KBP A;  2NYL C;  1OID A;  4TUI A;  5J28 A;  4UT3 B;  3DSD A;  5JPF A;  2P6B A;  3GVE A;  2KKN A;  2NPP C;  2WDE A;  3H63 A;  4F0Z A;  5GTU A;  3RL3 A;  3IB8 A;  1S3N A;  2NXF A;  4O43 A;  4MP0 A;  1SU1 A;  1WAR A;  2HY1 A;  4XPN A;  4ORA A;  4ZVZ A;  3IVD A;  1TCO A;  2QFR A;  4V0X A;  3IVE A;  4DSY A;  5INB A;  1T70 A;  2ZO9 B;  1V73 A;  4I5N C;  3K7W C;  1KBP A;  4WWL A;  1G5B A;  4KBP A;  4O24 A;  1OI8 A;  1UTE A;  1W24 A;  4H2G A;  5DNY A;  4O5G A;  4B2O A;  4H1S A;  3THN A;  3ZTV A;  1XM7 A;  2DFJ A;  1IT6 A;  3IB7 A;  4FBK A;  3E0J A;  3PSO A;  3TGH A;  3QFO A;  4DHL A;  2YVT A;  4MOY A;  1HP1 A;  2HYP A;  4ORB A;  2WDC A;  3D03 A;  3V4Y A;  5B8I A;  1UF3 A;  1S8E A;  4JA7 A;  1USH A;  1QFC A;  3HVQ A;  4V0W A;  3H62 B;  2NYM C;  1S70 A;  2WDF A;  2O8A A;  2O8G A;  1T71 A;  3C9F A;  1AUI A;  1HPU A;  2IE3 C;  2R17 A;  2WDD A;  3JYF A;  4H1Y P;  4OR9 A;  1OIE A;  3E7B A;  5JPE A;  2ZOA A;  3P71 C;  2AHD A;  3EGG A;  3DSC A;  3K7V C;  1II7 A; 
#chains in the Genus database with same CATH homology
 3H61 A;  4LU9 A;  3H68 A;  1HO5 A;  2ZBM A;  3DW8 C;  3FGA C;  3ICF A;  4I5L C;  4DT2 A;  3LL8 A;  3THO B;  1MF8 A;  4NZV A;  4ORC A;  1QHW A;  4UWQ A;  1S95 A;  3ZU0 A;  2BCD A;  2DXL A;  4H2B A;  5JJT A;  4UT3 A;  2IE4 C;  4FBW A;  2DXN A;  3T1I A;  5IOH A;  4HD0 A;  4KKZ A;  1Z2W A;  2YEQ A;  3H66 A;  3RL5 A;  2Z72 A;  1WAO 1;  4Q7F A;  4J6O A;  2XMO A;  4LAC C;  4IYP C;  3RL4 A;  1U32 A;  3N5U A;  3QFM A;  5HPE A;  3H67 A;  3QG5 C;  3AUZ A;  3RQZ A;  3FLO A;  4FBQ A;  2GJU A;  2Z1A A;  5C1V A;  1XZW A;  2JOG A;  4TUG A;  3AV0 A;  4LTY A;  4G9J A;  4H2F A;  4YKE A;  3QFN A;  1FJM A;  3PSN A;  2QJC A;  3C5W C;  2IAE C;  2BDX A;  5F3W A;  5EQV A;  3H69 A;  4IL1 A;  2BQ8 X;  4UT2 A;  2CV9 A;  1Z2X A;  3H64 A;  4FCX A;  4O4K A;  1JK7 A;  4MOV A;  2QFP A;  2Z06 A;  3H60 A;  3E7A A;  3QFK A;  4V0V A;  2Q8U A;  2HYO A;  3CK2 A;  1NNW A;  2A22 A;  1M63 A;  4H2I A;  3EGH A;  4M0V A;  4JA9 A;  1S3M A;  4ZX2 A;  1S3L A;  2USH A;  3KBP A;  2NYL C;  1OID A;  4TUI A;  5J28 A;  4UT3 B;  3DSD A;  5JPF A;  2P6B A;  3GVE A;  2KKN A;  2NPP C;  2WDE A;  3H63 A;  4F0Z A;  5GTU A;  3RL3 A;  3IB8 A;  1S3N A;  2NXF A;  4O43 A;  4MP0 A;  1SU1 A;  1WAR A;  2HY1 A;  4XPN A;  4ORA A;  4ZVZ A;  3IVD A;  1TCO A;  2QFR A;  4V0X A;  3IVE A;  4DSY A;  5INB A;  1T70 A;  2ZO9 B;  1V73 A;  4I5N C;  3K7W C;  1KBP A;  4WWL A;  1G5B A;  4KBP A;  4O24 A;  1OI8 A;  1UTE A;  1W24 A;  4H2G A;  5DNY A;  4O5G A;  4B2O A;  4H1S A;  3THN A;  3ZTV A;  1XM7 A;  2DFJ A;  1IT6 A;  3IB7 A;  4FBK A;  3E0J A;  3PSO A;  3TGH A;  3QFO A;  4DHL A;  2YVT A;  4MOY A;  1HP1 A;  2HYP A;  4ORB A;  2WDC A;  3D03 A;  3V4Y A;  5B8I A;  1UF3 A;  1S8E A;  4JA7 A;  1USH A;  1QFC A;  3HVQ A;  4V0W A;  3H62 B;  2NYM C;  1S70 A;  2WDF A;  2O8A A;  2O8G A;  1T71 A;  3C9F A;  1AUI A;  1HPU A;  2IE3 C;  2R17 A;  2WDD A;  3JYF A;  4H1Y P;  4OR9 A;  1OIE A;  3E7B A;  5JPE A;  2ZOA A;  3P71 C;  2AHD A;  3EGG A;  3DSC A;  3K7V C;  1II7 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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