3ZU0A

Structure of haemophilus influenzae nad nucleotidase (nadn)
Total Genus 201
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
201
sequence length
563
structure length
562
Chain Sequence
HKAVELSILHINDHHSYLEPHETRINLNGQQTKVDIGGFSAVNAKLNKLRKKYKNPLVLHAGDAITGTLYFTLFGGSADAAVMNAGNFHYFTLGNHEFDAGNEGLLKLLEPLKIPVLSANVIPDKSSILYNKWKPYDIFTVDGEKIAIIGLDTVNKTVNSSSPGKDVKFYDEIATAQIMANALKQQGINKIILLSHAGSEKNIEIAQKVNDIDVIVTGDSHYLYGNDELRSLKLPVIYEYPLEFKNPNGEPVFVMEGWAYSAVVGDLGVKFSPEGIASITRKIPHVLMSSHKLQVKNSEGKWAELTGDERKKALDTLKSMKSISLDDHDAKTDKLIAKYKSEKDRLAQEIVGVITGSAMPGGSANRIPNKAGSNPEGSIATRFIAETMYNELKTVDLTIQNAGGVRADILPGNVTFNDAYTFLPFGNTLYTYKMEGSLVKQVLEDAMQFALVDGSTGAFPYGAGIRYEANETPNAEGKRLVSVEVLNKTQQWEPIDDNKRYLVGTNAYVAGGKDGYKTFGKLFNDPKYEGVDTYLPDAESFIKFMKKHPHFEAYTSSNVKFN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The High-Resolution Crystal Structure of Periplasmic Haemophilus Influenzae Nad Nucleotidase Reveals a Novel Enzymatic Function of Human Cd73 Related to Nad Metabolism.
pubmed doi rcsb
source organism Haemophilus influenzae
molecule tags Hydrolase
molecule keywords NAD NUCLEOTIDASE
total genus 201
structure length 562
sequence length 563
chains with identical sequence B
ec nomenclature ec 3.1.3.5: 5'-nucleotidase.
pdb deposition date 2011-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF02872 5_nucleotid_C 5'-nucleotidase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3zu0A01
3.90.780.10 Alpha Beta Alpha-Beta Complex 5'-nucleotidase; domain 2 5'-Nucleotidase, C-terminal domain 3zu0A02
2O8AA 1S3NA 3IB8A 1S8EA 1G5BA 2JOGA 4FCXA 4JA9A 1WARA 2QJCA 3E7AA 4FBWA 3LL8A 2IAEC 3RL5A 3THNA 4V0VA 1AUIA 5C1VA 5EQVA 3V4YA 2BDXA 4M0VA 4V0WA 5IOHA 1S3LA 4LU9A 1NNWA 2ZBMA 3EGGA 2YVTA 5F3WA 2BQ8X 1FJMA 3PSNA 4B2OA 1OI8A 2Z06A 4ORBA 4TUGA 4H1SA 4G9JA 4O43A 3C5WC 2P6BA 4I5LC 4Q7FA 4ZX2A 3H67A 4TUIA 3DSDA 1USHA 4H1YP 4ORAA 3H62B 3PSOA 2QFPA 2USHA 3IB7A 1II7A 2O8GA 4OR9A 3QFNA 4O5GA 2Q8UA 2XMOA 2Z1AA 3JYFA 3RL3A 4H2FA 5GTUA 4MOVA 3H66A 4KKZA 3TGHA 2NPPC 3QFKA 4MOYA 1QHWA 1Z2XA 2NYMC 3QFOA 1JK7A 4ZVZA 3N5UA 1OIEA 2WDFA 1M63A 2IE4C 1T71A 4DT2A 1V73A 4NZVA 3DW8C 4MP0A 4JA7A 2KKNA 1Z2WA 3H61A 3H64A 4H2IA 4IL1A 3THOB 1MF8A 3KBPA 1HPUA 4ORCA 4DHLA 5INBA 3E7BA 4FBQA 4UT2A 3FGAC 2QFRA 4YKEA 3RL4A 5JPFA 2A22A 1KBPA 3ICFA 3H63A 1S3MA 4H2BA 4O24A 5J28A 1U32A 4UWQA 2HY1A 1XM7A 4UT3A 4DSYA 2NYLC 1SU1A 3H60A 4LACC 1UTEA 5B8IA 2Z72A 2DFJA 2NXFA 1QFCA 3H68A 3IVEA 3EGHA 5HPEA 3C9FA 1WAO1 3P71C 3K7WC 3DSCA 2AHDA 4LTYA 4WWLA 3QG5C 2HYOA 3HVQA 1TCOA 3AV0A 1OIDA 1HP1A 5DNYA 4V0XA 3AUZA 1XZWA 4FBKA 1IT6A 4F0ZA 4IYPC 4J6OA 4H2GA 3QFMA 2WDCA 1S70A 3RQZA 3ZTVA 2CV9A 5JPEA 1S95A 2WDDA 2R17A 3CK2A 3GVEA 3ZU0A 1HO5A 2HYPA 5JJTA 4I5NC 2GJUA 2BCDA 2WDEA 4HD0A 4UT3B 1UF3A 1W24A 3T1IA 4XPNA 2IE3C 1T70A 3H69A 3IVDA 4KBPA 4O4KA 3K7VC
chains in the Genus database with same CATH superfamily
2O8AA 1S3NA 3IB8A 1S8EA 1G5BA 2JOGA 4FCXA 4JA9A 2DXLA 1WARA 2QJCA 3E7AA 4FBWA 3LL8A 2IAEC 3RL5A 3THNA 4V0VA 1AUIA 5C1VA 5EQVA 3V4YA 2BDXA 4M0VA 4V0WA 5IOHA 1S3LA 4LU9A 1NNWA 2ZBMA 3EGGA 2YVTA 5F3WA 2BQ8X 3E0JA 1FJMA 3PSNA 4B2OA 1OI8A 2Z06A 4ORBA 4TUGA 4H1SA 4G9JA 4O43A 3C5WC 2P6BA 4I5LC 4Q7FA 4ZX2A 3H67A 3D03A 4TUIA 3DSDA 1USHA 4H1YP 4ORAA 3H62B 3PSOA 2QFPA 2USHA 3IB7A 1II7A 2O8GA 4OR9A 3QFNA 4O5GA 2Q8UA 2XMOA 2Z1AA 3FLOA 3JYFA 3RL3A 4H2FA 2YEQA 5GTUA 4MOVA 3H66A 4KKZA 3TGHA 2NPPC 3QFKA 4MOYA 1QHWA 1Z2XA 2NYMC 3QFOA 1JK7A 4ZVZA 3N5UA 1OIEA 2WDFA 1M63A 2IE4C 1T71A 4DT2A 1V73A 4NZVA 3DW8C 4MP0A 4JA7A 2KKNA 1Z2WA 3H61A 3H64A 4H2IA 4IL1A 3THOB 1MF8A 3KBPA 1HPUA 4ORCA 4DHLA 5INBA 3E7BA 4FBQA 4UT2A 3FGAC 2QFRA 4YKEA 3RL4A 5JPFA 2A22A 1KBPA 3ICFA 3H63A 1S3MA 4H2BA 4O24A 5J28A 1U32A 4UWQA 2HY1A 1XM7A 4UT3A 4DSYA 2NYLC 1SU1A 3H60A 4LACC 1UTEA 5B8IA 2Z72A 2DFJA 2NXFA 1QFCA 3H68A 3IVEA 3EGHA 5HPEA 3C9FA 1WAO1 3P71C 3K7WC 3DSCA 2AHDA 4LTYA 4WWLA 3QG5C 2HYOA 3HVQA 1TCOA 3AV0A 1OIDA 1HP1A 5DNYA 4V0XA 3AUZA 1XZWA 4FBKA 1IT6A 2ZO9B 4F0ZA 4IYPC 4J6OA 4H2GA 3QFMA 2WDCA 1S70A 3RQZA 3ZTVA 2CV9A 5JPEA 1S95A 2WDDA 2R17A 3CK2A 3GVEA 3ZU0A 1HO5A 2HYPA 2ZOAA 5JJTA 4I5NC 2GJUA 2BCDA 2WDEA 4HD0A 4UT3B 1UF3A 1W24A 3T1IA 4XPNA 2IE3C 1T70A 3H69A 3IVDA 4KBPA 4O4KA 2DXNA 3K7VC
chains in the Genus database with same CATH topology
2O8AA 1S3NA 3IB8A 1S8EA 1G5BA 2JOGA 4FCXA 4JA9A 2DXLA 1WARA 2QJCA 3E7AA 4FBWA 3LL8A 2IAEC 3RL5A 3THNA 4V0VA 1AUIA 5C1VA 5EQVA 3V4YA 2BDXA 4M0VA 4V0WA 5IOHA 1S3LA 4LU9A 1NNWA 2ZBMA 3EGGA 2YVTA 5F3WA 2BQ8X 3E0JA 1FJMA 3PSNA 4B2OA 1OI8A 2Z06A 4ORBA 4TUGA 4H1SA 4G9JA 4O43A 3C5WC 2P6BA 4I5LC 4Q7FA 4ZX2A 3H67A 3D03A 4TUIA 3DSDA 1USHA 4H1YP 4ORAA 3H62B 3PSOA 2QFPA 2USHA 3IB7A 1II7A 2O8GA 4OR9A 3QFNA 4O5GA 2Q8UA 2XMOA 2Z1AA 3FLOA 3JYFA 3RL3A 4H2FA 2YEQA 5GTUA 4MOVA 3H66A 4KKZA 3TGHA 2NPPC 3QFKA 4MOYA 1QHWA 1Z2XA 2NYMC 3QFOA 1JK7A 4ZVZA 3N5UA 1OIEA 2WDFA 1M63A 2IE4C 1T71A 4DT2A 1V73A 4NZVA 3DW8C 4MP0A 4JA7A 2KKNA 1Z2WA 3H61A 3H64A 4H2IA 4IL1A 3THOB 1MF8A 3KBPA 1HPUA 4ORCA 4DHLA 5INBA 3E7BA 4FBQA 4UT2A 3FGAC 2QFRA 4YKEA 3RL4A 5JPFA 2A22A 1KBPA 3ICFA 3H63A 1S3MA 4H2BA 4O24A 5J28A 1U32A 4UWQA 2HY1A 1XM7A 4UT3A 4DSYA 2NYLC 1SU1A 3H60A 4LACC 1UTEA 5B8IA 2Z72A 2DFJA 2NXFA 1QFCA 3H68A 3IVEA 3EGHA 5HPEA 3C9FA 1WAO1 3P71C 3K7WC 3DSCA 2AHDA 4LTYA 4WWLA 3QG5C 2HYOA 3HVQA 1TCOA 3AV0A 1OIDA 1HP1A 5DNYA 4V0XA 3AUZA 1XZWA 4FBKA 1IT6A 2ZO9B 4F0ZA 4IYPC 4J6OA 4H2GA 3QFMA 2WDCA 1S70A 3RQZA 3ZTVA 2CV9A 5JPEA 1S95A 2WDDA 2R17A 3CK2A 3GVEA 3ZU0A 1HO5A 2HYPA 2ZOAA 5JJTA 4I5NC 2GJUA 2BCDA 2WDEA 4HD0A 4UT3B 1UF3A 1W24A 3T1IA 4XPNA 2IE3C 1T70A 3H69A 3IVDA 4KBPA 4O4KA 2DXNA 3K7VC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O8A A;  1S3N A;  3IB8 A;  1S8E A;  1G5B A;  2JOG A;  4FCX A;  4JA9 A;  1WAR A;  2QJC A;  3E7A A;  4FBW A;  3LL8 A;  2IAE C;  3RL5 A;  3THN A;  4V0V A;  1AUI A;  5C1V A;  5EQV A;  3V4Y A;  2BDX A;  4M0V A;  4V0W A;  5IOH A;  1S3L A;  4LU9 A;  1NNW A;  2ZBM A;  3EGG A;  2YVT A;  5F3W A;  2BQ8 X;  1FJM A;  3PSN A;  4B2O A;  1OI8 A;  2Z06 A;  4ORB A;  4TUG A;  4H1S A;  4G9J A;  4O43 A;  3C5W C;  2P6B A;  4I5L C;  4Q7F A;  4ZX2 A;  3H67 A;  4TUI A;  3DSD A;  1USH A;  4H1Y P;  4ORA A;  3H62 B;  3PSO A;  2QFP A;  2USH A;  3IB7 A;  1II7 A;  2O8G A;  4OR9 A;  3QFN A;  4O5G A;  2Q8U A;  2XMO A;  2Z1A A;  3JYF A;  3RL3 A;  4H2F A;  5GTU A;  4MOV A;  3H66 A;  4KKZ A;  3TGH A;  2NPP C;  3QFK A;  4MOY A;  1QHW A;  1Z2X A;  2NYM C;  3QFO A;  1JK7 A;  4ZVZ A;  3N5U A;  1OIE A;  2WDF A;  1M63 A;  2IE4 C;  1T71 A;  4DT2 A;  1V73 A;  4NZV A;  3DW8 C;  4MP0 A;  4JA7 A;  2KKN A;  1Z2W A;  3H61 A;  3H64 A;  4H2I A;  4IL1 A;  3THO B;  1MF8 A;  3KBP A;  1HPU A;  4ORC A;  4DHL A;  5INB A;  3E7B A;  4FBQ A;  4UT2 A;  3FGA C;  2QFR A;  4YKE A;  3RL4 A;  5JPF A;  2A22 A;  1KBP A;  3ICF A;  3H63 A;  1S3M A;  4H2B A;  4O24 A;  5J28 A;  1U32 A;  4UWQ A;  2HY1 A;  1XM7 A;  4UT3 A;  4DSY A;  2NYL C;  1SU1 A;  3H60 A;  4LAC C;  1UTE A;  5B8I A;  2Z72 A;  2DFJ A;  2NXF A;  1QFC A;  3H68 A;  3IVE A;  3EGH A;  5HPE A;  3C9F A;  1WAO 1;  3P71 C;  3K7W C;  3DSC A;  2AHD A;  4LTY A;  4WWL A;  3QG5 C;  2HYO A;  3HVQ A;  1TCO A;  3AV0 A;  1OID A;  1HP1 A;  5DNY A;  4V0X A;  3AUZ A;  1XZW A;  4FBK A;  1IT6 A;  4F0Z A;  4IYP C;  4J6O A;  4H2G A;  3QFM A;  2WDC A;  1S70 A;  3RQZ A;  3ZTV A;  2CV9 A;  5JPE A;  1S95 A;  2WDD A;  2R17 A;  3CK2 A;  3GVE A;  3ZU0 A;  1HO5 A;  2HYP A;  5JJT A;  4I5N C;  2GJU A;  2BCD A;  2WDE A;  4HD0 A;  4UT3 B;  1UF3 A;  1W24 A;  3T1I A;  4XPN A;  2IE3 C;  1T70 A;  3H69 A;  3IVD A;  4KBP A;  4O4K A;  3K7V C; 
#chains in the Genus database with same CATH topology
 2O8A A;  1S3N A;  3IB8 A;  1S8E A;  1G5B A;  2JOG A;  4FCX A;  4JA9 A;  2DXL A;  1WAR A;  2QJC A;  3E7A A;  4FBW A;  3LL8 A;  2IAE C;  3RL5 A;  3THN A;  4V0V A;  1AUI A;  5C1V A;  5EQV A;  3V4Y A;  2BDX A;  4M0V A;  4V0W A;  5IOH A;  1S3L A;  4LU9 A;  1NNW A;  2ZBM A;  3EGG A;  2YVT A;  5F3W A;  2BQ8 X;  3E0J A;  1FJM A;  3PSN A;  4B2O A;  1OI8 A;  2Z06 A;  4ORB A;  4TUG A;  4H1S A;  4G9J A;  4O43 A;  3C5W C;  2P6B A;  4I5L C;  4Q7F A;  4ZX2 A;  3H67 A;  3D03 A;  4TUI A;  3DSD A;  1USH A;  4H1Y P;  4ORA A;  3H62 B;  3PSO A;  2QFP A;  2USH A;  3IB7 A;  1II7 A;  2O8G A;  4OR9 A;  3QFN A;  4O5G A;  2Q8U A;  2XMO A;  2Z1A A;  3FLO A;  3JYF A;  3RL3 A;  4H2F A;  2YEQ A;  5GTU A;  4MOV A;  3H66 A;  4KKZ A;  3TGH A;  2NPP C;  3QFK A;  4MOY A;  1QHW A;  1Z2X A;  2NYM C;  3QFO A;  1JK7 A;  4ZVZ A;  3N5U A;  1OIE A;  2WDF A;  1M63 A;  2IE4 C;  1T71 A;  4DT2 A;  1V73 A;  4NZV A;  3DW8 C;  4MP0 A;  4JA7 A;  2KKN A;  1Z2W A;  3H61 A;  3H64 A;  4H2I A;  4IL1 A;  3THO B;  1MF8 A;  3KBP A;  1HPU A;  4ORC A;  4DHL A;  5INB A;  3E7B A;  4FBQ A;  4UT2 A;  3FGA C;  2QFR A;  4YKE A;  3RL4 A;  5JPF A;  2A22 A;  1KBP A;  3ICF A;  3H63 A;  1S3M A;  4H2B A;  4O24 A;  5J28 A;  1U32 A;  4UWQ A;  2HY1 A;  1XM7 A;  4UT3 A;  4DSY A;  2NYL C;  1SU1 A;  3H60 A;  4LAC C;  1UTE A;  5B8I A;  2Z72 A;  2DFJ A;  2NXF A;  1QFC A;  3H68 A;  3IVE A;  3EGH A;  5HPE A;  3C9F A;  1WAO 1;  3P71 C;  3K7W C;  3DSC A;  2AHD A;  4LTY A;  4WWL A;  3QG5 C;  2HYO A;  3HVQ A;  1TCO A;  3AV0 A;  1OID A;  1HP1 A;  5DNY A;  4V0X A;  3AUZ A;  1XZW A;  4FBK A;  1IT6 A;  2ZO9 B;  4F0Z A;  4IYP C;  4J6O A;  4H2G A;  3QFM A;  2WDC A;  1S70 A;  3RQZ A;  3ZTV A;  2CV9 A;  5JPE A;  1S95 A;  2WDD A;  2R17 A;  3CK2 A;  3GVE A;  3ZU0 A;  1HO5 A;  2HYP A;  2ZOA A;  5JJT A;  4I5N C;  2GJU A;  2BCD A;  2WDE A;  4HD0 A;  4UT3 B;  1UF3 A;  1W24 A;  3T1I A;  4XPN A;  2IE3 C;  1T70 A;  3H69 A;  3IVD A;  4KBP A;  4O4K A;  2DXN A;  3K7V C; 
#chains in the Genus database with same CATH homology
 2O8A A;  1S3N A;  3IB8 A;  1S8E A;  1G5B A;  2JOG A;  4FCX A;  4JA9 A;  2DXL A;  1WAR A;  2QJC A;  3E7A A;  4FBW A;  3LL8 A;  2IAE C;  3RL5 A;  3THN A;  4V0V A;  1AUI A;  5C1V A;  5EQV A;  3V4Y A;  2BDX A;  4M0V A;  4V0W A;  5IOH A;  1S3L A;  4LU9 A;  1NNW A;  2ZBM A;  3EGG A;  2YVT A;  5F3W A;  2BQ8 X;  3E0J A;  1FJM A;  3PSN A;  4B2O A;  1OI8 A;  2Z06 A;  4ORB A;  4TUG A;  4H1S A;  4G9J A;  4O43 A;  3C5W C;  2P6B A;  4I5L C;  4Q7F A;  4ZX2 A;  3H67 A;  3D03 A;  4TUI A;  3DSD A;  1USH A;  4H1Y P;  4ORA A;  3H62 B;  3PSO A;  2QFP A;  2USH A;  3IB7 A;  1II7 A;  2O8G A;  4OR9 A;  3QFN A;  4O5G A;  2Q8U A;  2XMO A;  2Z1A A;  3FLO A;  3JYF A;  3RL3 A;  4H2F A;  2YEQ A;  5GTU A;  4MOV A;  3H66 A;  4KKZ A;  3TGH A;  2NPP C;  3QFK A;  4MOY A;  1QHW A;  1Z2X A;  2NYM C;  3QFO A;  1JK7 A;  4ZVZ A;  3N5U A;  1OIE A;  2WDF A;  1M63 A;  2IE4 C;  1T71 A;  4DT2 A;  1V73 A;  4NZV A;  3DW8 C;  4MP0 A;  4JA7 A;  2KKN A;  1Z2W A;  3H61 A;  3H64 A;  4H2I A;  4IL1 A;  3THO B;  1MF8 A;  3KBP A;  1HPU A;  4ORC A;  4DHL A;  5INB A;  3E7B A;  4FBQ A;  4UT2 A;  3FGA C;  2QFR A;  4YKE A;  3RL4 A;  5JPF A;  2A22 A;  1KBP A;  3ICF A;  3H63 A;  1S3M A;  4H2B A;  4O24 A;  5J28 A;  1U32 A;  4UWQ A;  2HY1 A;  1XM7 A;  4UT3 A;  4DSY A;  2NYL C;  1SU1 A;  3H60 A;  4LAC C;  1UTE A;  5B8I A;  2Z72 A;  2DFJ A;  2NXF A;  1QFC A;  3H68 A;  3IVE A;  3EGH A;  5HPE A;  3C9F A;  1WAO 1;  3P71 C;  3K7W C;  3DSC A;  2AHD A;  4LTY A;  4WWL A;  3QG5 C;  2HYO A;  3HVQ A;  1TCO A;  3AV0 A;  1OID A;  1HP1 A;  5DNY A;  4V0X A;  3AUZ A;  1XZW A;  4FBK A;  1IT6 A;  2ZO9 B;  4F0Z A;  4IYP C;  4J6O A;  4H2G A;  3QFM A;  2WDC A;  1S70 A;  3RQZ A;  3ZTV A;  2CV9 A;  5JPE A;  1S95 A;  2WDD A;  2R17 A;  3CK2 A;  3GVE A;  3ZU0 A;  1HO5 A;  2HYP A;  2ZOA A;  5JJT A;  4I5N C;  2GJU A;  2BCD A;  2WDE A;  4HD0 A;  4UT3 B;  1UF3 A;  1W24 A;  3T1I A;  4XPN A;  2IE3 C;  1T70 A;  3H69 A;  3IVD A;  4KBP A;  4O4K A;  2DXN A;  3K7V C; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...