3ZU0A

Structure of haemophilus influenzae nad nucleotidase (nadn)
Total Genus 201
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
201
sequence length
563
structure length
562
Chain Sequence
HKAVELSILHINDHHSYLEPHETRINLNGQQTKVDIGGFSAVNAKLNKLRKKYKNPLVLHAGDAITGTLYFTLFGGSADAAVMNAGNFHYFTLGNHEFDAGNEGLLKLLEPLKIPVLSANVIPDKSSILYNKWKPYDIFTVDGEKIAIIGLDTVNKTVNSSSPGKDVKFYDEIATAQIMANALKQQGINKIILLSHAGSEKNIEIAQKVNDIDVIVTGDSHYLYGNDELRSLKLPVIYEYPLEFKNPNGEPVFVMEGWAYSAVVGDLGVKFSPEGIASITRKIPHVLMSSHKLQVKNSEGKWAELTGDERKKALDTLKSMKSISLDDHDAKTDKLIAKYKSEKDRLAQEIVGVITGSAMPGGSANRIPNKAGSNPEGSIATRFIAETMYNELKTVDLTIQNAGGVRADILPGNVTFNDAYTFLPFGNTLYTYKMEGSLVKQVLEDAMQFALVDGSTGAFPYGAGIRYEANETPNAEGKRLVSVEVLNKTQQWEPIDDNKRYLVGTNAYVAGGKDGYKTFGKLFNDPKYEGVDTYLPDAESFIKFMKKHPHFEAYTSSNVKFN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The High-Resolution Crystal Structure of Periplasmic Haemophilus Influenzae Nad Nucleotidase Reveals a Novel Enzymatic Function of Human Cd73 Related to Nad Metabolism.
pubmed doi rcsb
source organism Haemophilus influenzae
molecule tags Hydrolase
molecule keywords NAD NUCLEOTIDASE
total genus 201
structure length 562
sequence length 563
chains with identical sequence B
ec nomenclature ec 3.1.3.5: 5'-nucleotidase.
pdb deposition date 2011-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF02872 5_nucleotid_C 5'-nucleotidase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3zu0A01
3.90.780.10 Alpha Beta Alpha-Beta Complex 5'-nucleotidase; domain 2 5'-Nucleotidase, C-terminal domain 3zu0A02
4FBWA 4YKEA 4I5LC 3LL8A 2NYMC 4V0WA 2R17A 4IL1A 4XPNA 1S3LA 2IE3C 1Z2XA 5IOHA 2O8GA 4TUGA 1W24A 5JPFA 3AV0A 4KBPA 3P71C 3H61A 3PSNA 2Z1AA 4FBKA 2Z72A 2QFPA 5B8IA 3KBPA 2ZBMA 4MOVA 1T71A 4DT2A 4G9JA 1KBPA 4O43A 3ZTVA 4HD0A 3K7WC 3C9FA 1XM7A 2HY1A 4I5NC 3RL4A 4ZX2A 3PSOA 1QHWA 4J6OA 1XZWA 4JA7A 4F0ZA 2BQ8X 3TGHA 3H63A 3RL3A 3THNA 3IVDA 1AUIA 2AHDA 4H2BA 4O24A 4M0VA 1SU1A 1TCOA 1M63A 4NZVA 3C5WC 3QFNA 4H1YP 2P6BA 2WDFA 1G5BA 3DW8C 3E7BA 5C1VA 2HYOA 2HYPA 3IB7A 3EGHA 4UT2A 2IAEC 3H68A 2O8AA 2QFRA 3N5UA 2Z06A 3E7AA 3IVEA 1OI8A 3QFMA 5EQVA 1S3NA 4Q7FA 1QFCA 2XMOA 4LU9A 4V0VA 1HP1A 3T1IA 1Z2WA 2A22A 4H2IA 3QFOA 4ORBA 3H60A 4MP0A 1WAO1 2NYLC 1S8EA 3H62B 1MF8A 4FBQA 4ORAA 2QJCA 4V0XA 1NNWA 3H67A 2USHA 4H2FA 1S3MA 1V73A 1UF3A 4H2GA 5F3WA 3H69A 2YVTA 2BCDA 3V4YA 4IYPC 5JPEA 4JA9A 4LTYA 1II7A 2WDCA 4O5GA 3RL5A 5INBA 1HO5A 4OR9A 4UWQA 3AUZA 5J28A 2NXFA 1USHA 4MOYA 2NPPC 3JYFA 4ORCA 5JJTA 2DFJA 1IT6A 4LACC 1WARA 4TUIA 3ZU0A 3RQZA 4UT3B 2KKNA 2WDDA 2GJUA 2Q8UA 3GVEA 1UTEA 2WDEA 1S70A 4KKZA 1T70A 2IE4C 5HPEA 3FGAC 4O4KA 1S95A 3DSDA 4DHLA 3DSCA 3EGGA 1HPUA 4ZVZA 3QG5C 1OIDA 3THOB 4H1SA 3H64A 3ICFA 3CK2A 4FCXA 4DSYA 2CV9A 1JK7A 4UT3A 3H66A 5DNYA 3K7VC 1FJMA 2JOGA 3HVQA 3QFKA 4B2OA 3IB8A 4WWLA 1OIEA 5GTUA 2BDXA 1U32A
chains in the Genus database with same CATH superfamily
4FBWA 4YKEA 4I5LC 3LL8A 2NYMC 4V0WA 2R17A 4IL1A 4XPNA 1S3LA 2IE3C 1Z2XA 5IOHA 2O8GA 4TUGA 1W24A 5JPFA 3AV0A 4KBPA 3P71C 3H61A 3PSNA 2Z1AA 2ZO9B 2Z72A 2QFPA 4FBKA 3KBPA 5B8IA 2ZBMA 4MOVA 1T71A 4DT2A 4G9JA 1KBPA 4O43A 3ZTVA 4HD0A 3K7WC 3C9FA 1XM7A 2HY1A 4I5NC 3RL4A 4ZX2A 3PSOA 1QHWA 4J6OA 1XZWA 4JA7A 4F0ZA 2BQ8X 3TGHA 3H63A 3RL3A 3THNA 3IVDA 1AUIA 2AHDA 4H2BA 4O24A 4M0VA 1SU1A 1TCOA 1M63A 4NZVA 3C5WC 3QFNA 4H1YP 2P6BA 2WDFA 1G5BA 3DW8C 3E7BA 5C1VA 2HYOA 2HYPA 3IB7A 2YEQA 3EGHA 4UT2A 2IAEC 3H68A 2O8AA 2QFRA 3FLOA 3N5UA 2Z06A 3E7AA 3IVEA 1OI8A 3QFMA 5EQVA 1S3NA 4Q7FA 1QFCA 2XMOA 4LU9A 4V0VA 1HP1A 3T1IA 1Z2WA 2A22A 4H2IA 3QFOA 4ORBA 3H60A 4MP0A 1WAO1 2NYLC 1S8EA 3H62B 1MF8A 4FBQA 4ORAA 2QJCA 4V0XA 1NNWA 3H67A 2USHA 4H2FA 1S3MA 1V73A 1UF3A 4H2GA 5F3WA 3D03A 3H69A 2DXLA 2BCDA 2YVTA 3V4YA 4IYPC 5JPEA 4JA9A 4LTYA 1II7A 2WDCA 4O5GA 3RL5A 5INBA 1HO5A 4OR9A 4UWQA 3AUZA 5J28A 2NXFA 1USHA 4MOYA 2NPPC 3JYFA 4ORCA 5JJTA 2DFJA 1IT6A 4LACC 1WARA 4TUIA 3ZU0A 3RQZA 2DXNA 4UT3B 2KKNA 2WDDA 2GJUA 2Q8UA 3GVEA 1UTEA 2WDEA 1S70A 4KKZA 1T70A 2IE4C 5HPEA 3FGAC 4O4KA 1S95A 3DSDA 4DHLA 3DSCA 3EGGA 1HPUA 4ZVZA 3QG5C 1OIDA 3THOB 4H1SA 3H64A 3ICFA 3CK2A 4FCXA 4DSYA 3E0JA 2CV9A 1JK7A 4UT3A 3H66A 5DNYA 2ZOAA 3K7VC 1FJMA 2JOGA 3HVQA 3QFKA 4B2OA 3IB8A 4WWLA 1OIEA 5GTUA 2BDXA 1U32A
chains in the Genus database with same CATH topology
4FBWA 4YKEA 4I5LC 3LL8A 2NYMC 4V0WA 2R17A 4IL1A 4XPNA 1S3LA 2IE3C 1Z2XA 5IOHA 2O8GA 4TUGA 1W24A 5JPFA 3AV0A 4KBPA 3P71C 3H61A 3PSNA 2Z1AA 2ZO9B 2Z72A 2QFPA 4FBKA 3KBPA 5B8IA 2ZBMA 4MOVA 1T71A 4DT2A 4G9JA 1KBPA 4O43A 3ZTVA 4HD0A 3K7WC 3C9FA 1XM7A 2HY1A 4I5NC 3RL4A 4ZX2A 3PSOA 1QHWA 4J6OA 1XZWA 4JA7A 4F0ZA 2BQ8X 3TGHA 3H63A 3RL3A 3THNA 3IVDA 1AUIA 2AHDA 4H2BA 4O24A 4M0VA 1SU1A 1TCOA 1M63A 4NZVA 3C5WC 3QFNA 4H1YP 2P6BA 2WDFA 1G5BA 3DW8C 3E7BA 5C1VA 2HYOA 2HYPA 3IB7A 2YEQA 3EGHA 4UT2A 2IAEC 3H68A 2O8AA 2QFRA 3FLOA 3N5UA 2Z06A 3E7AA 3IVEA 1OI8A 3QFMA 5EQVA 1S3NA 4Q7FA 1QFCA 2XMOA 4LU9A 4V0VA 1HP1A 3T1IA 1Z2WA 2A22A 4H2IA 3QFOA 4ORBA 3H60A 4MP0A 1WAO1 2NYLC 1S8EA 3H62B 1MF8A 4FBQA 4ORAA 2QJCA 4V0XA 1NNWA 3H67A 2USHA 4H2FA 1S3MA 1V73A 1UF3A 4H2GA 5F3WA 3D03A 3H69A 2DXLA 2BCDA 2YVTA 3V4YA 4IYPC 5JPEA 4JA9A 4LTYA 1II7A 2WDCA 4O5GA 3RL5A 5INBA 1HO5A 4OR9A 4UWQA 3AUZA 5J28A 2NXFA 1USHA 4MOYA 2NPPC 3JYFA 4ORCA 5JJTA 2DFJA 1IT6A 4LACC 1WARA 4TUIA 3ZU0A 3RQZA 2DXNA 4UT3B 2KKNA 2WDDA 2GJUA 2Q8UA 3GVEA 1UTEA 2WDEA 1S70A 4KKZA 1T70A 2IE4C 5HPEA 3FGAC 4O4KA 1S95A 3DSDA 4DHLA 3DSCA 3EGGA 1HPUA 4ZVZA 3QG5C 1OIDA 3THOB 4H1SA 3H64A 3ICFA 3CK2A 4FCXA 4DSYA 3E0JA 2CV9A 1JK7A 4UT3A 3H66A 5DNYA 2ZOAA 3K7VC 1FJMA 2JOGA 3HVQA 3QFKA 4B2OA 3IB8A 4WWLA 1OIEA 5GTUA 2BDXA 1U32A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FBW A;  4YKE A;  4I5L C;  3LL8 A;  2NYM C;  4V0W A;  2R17 A;  4IL1 A;  4XPN A;  1S3L A;  2IE3 C;  1Z2X A;  5IOH A;  2O8G A;  4TUG A;  1W24 A;  5JPF A;  3AV0 A;  4KBP A;  3P71 C;  3H61 A;  3PSN A;  2Z1A A;  4FBK A;  2Z72 A;  2QFP A;  5B8I A;  3KBP A;  2ZBM A;  4MOV A;  1T71 A;  4DT2 A;  4G9J A;  1KBP A;  4O43 A;  3ZTV A;  4HD0 A;  3K7W C;  3C9F A;  1XM7 A;  2HY1 A;  4I5N C;  3RL4 A;  4ZX2 A;  3PSO A;  1QHW A;  4J6O A;  1XZW A;  4JA7 A;  4F0Z A;  2BQ8 X;  3TGH A;  3H63 A;  3RL3 A;  3THN A;  3IVD A;  1AUI A;  2AHD A;  4H2B A;  4O24 A;  4M0V A;  1SU1 A;  1TCO A;  1M63 A;  4NZV A;  3C5W C;  3QFN A;  4H1Y P;  2P6B A;  2WDF A;  1G5B A;  3DW8 C;  3E7B A;  5C1V A;  2HYO A;  2HYP A;  3IB7 A;  3EGH A;  4UT2 A;  2IAE C;  3H68 A;  2O8A A;  2QFR A;  3N5U A;  2Z06 A;  3E7A A;  3IVE A;  1OI8 A;  3QFM A;  5EQV A;  1S3N A;  4Q7F A;  1QFC A;  2XMO A;  4LU9 A;  4V0V A;  1HP1 A;  3T1I A;  1Z2W A;  2A22 A;  4H2I A;  3QFO A;  4ORB A;  3H60 A;  4MP0 A;  1WAO 1;  2NYL C;  1S8E A;  3H62 B;  1MF8 A;  4FBQ A;  4ORA A;  2QJC A;  4V0X A;  1NNW A;  3H67 A;  2USH A;  4H2F A;  1S3M A;  1V73 A;  1UF3 A;  4H2G A;  5F3W A;  3H69 A;  2YVT A;  2BCD A;  3V4Y A;  4IYP C;  5JPE A;  4JA9 A;  4LTY A;  1II7 A;  2WDC A;  4O5G A;  3RL5 A;  5INB A;  1HO5 A;  4OR9 A;  4UWQ A;  3AUZ A;  5J28 A;  2NXF A;  1USH A;  4MOY A;  2NPP C;  3JYF A;  4ORC A;  5JJT A;  2DFJ A;  1IT6 A;  4LAC C;  1WAR A;  4TUI A;  3ZU0 A;  3RQZ A;  4UT3 B;  2KKN A;  2WDD A;  2GJU A;  2Q8U A;  3GVE A;  1UTE A;  2WDE A;  1S70 A;  4KKZ A;  1T70 A;  2IE4 C;  5HPE A;  3FGA C;  4O4K A;  1S95 A;  3DSD A;  4DHL A;  3DSC A;  3EGG A;  1HPU A;  4ZVZ A;  3QG5 C;  1OID A;  3THO B;  4H1S A;  3H64 A;  3ICF A;  3CK2 A;  4FCX A;  4DSY A;  2CV9 A;  1JK7 A;  4UT3 A;  3H66 A;  5DNY A;  3K7V C;  1FJM A;  2JOG A;  3HVQ A;  3QFK A;  4B2O A;  3IB8 A;  4WWL A;  1OIE A;  5GTU A;  2BDX A;  1U32 A; 
#chains in the Genus database with same CATH topology
 4FBW A;  4YKE A;  4I5L C;  3LL8 A;  2NYM C;  4V0W A;  2R17 A;  4IL1 A;  4XPN A;  1S3L A;  2IE3 C;  1Z2X A;  5IOH A;  2O8G A;  4TUG A;  1W24 A;  5JPF A;  3AV0 A;  4KBP A;  3P71 C;  3H61 A;  3PSN A;  2Z1A A;  2ZO9 B;  2Z72 A;  2QFP A;  4FBK A;  3KBP A;  5B8I A;  2ZBM A;  4MOV A;  1T71 A;  4DT2 A;  4G9J A;  1KBP A;  4O43 A;  3ZTV A;  4HD0 A;  3K7W C;  3C9F A;  1XM7 A;  2HY1 A;  4I5N C;  3RL4 A;  4ZX2 A;  3PSO A;  1QHW A;  4J6O A;  1XZW A;  4JA7 A;  4F0Z A;  2BQ8 X;  3TGH A;  3H63 A;  3RL3 A;  3THN A;  3IVD A;  1AUI A;  2AHD A;  4H2B A;  4O24 A;  4M0V A;  1SU1 A;  1TCO A;  1M63 A;  4NZV A;  3C5W C;  3QFN A;  4H1Y P;  2P6B A;  2WDF A;  1G5B A;  3DW8 C;  3E7B A;  5C1V A;  2HYO A;  2HYP A;  3IB7 A;  2YEQ A;  3EGH A;  4UT2 A;  2IAE C;  3H68 A;  2O8A A;  2QFR A;  3FLO A;  3N5U A;  2Z06 A;  3E7A A;  3IVE A;  1OI8 A;  3QFM A;  5EQV A;  1S3N A;  4Q7F A;  1QFC A;  2XMO A;  4LU9 A;  4V0V A;  1HP1 A;  3T1I A;  1Z2W A;  2A22 A;  4H2I A;  3QFO A;  4ORB A;  3H60 A;  4MP0 A;  1WAO 1;  2NYL C;  1S8E A;  3H62 B;  1MF8 A;  4FBQ A;  4ORA A;  2QJC A;  4V0X A;  1NNW A;  3H67 A;  2USH A;  4H2F A;  1S3M A;  1V73 A;  1UF3 A;  4H2G A;  5F3W A;  3D03 A;  3H69 A;  2DXL A;  2BCD A;  2YVT A;  3V4Y A;  4IYP C;  5JPE A;  4JA9 A;  4LTY A;  1II7 A;  2WDC A;  4O5G A;  3RL5 A;  5INB A;  1HO5 A;  4OR9 A;  4UWQ A;  3AUZ A;  5J28 A;  2NXF A;  1USH A;  4MOY A;  2NPP C;  3JYF A;  4ORC A;  5JJT A;  2DFJ A;  1IT6 A;  4LAC C;  1WAR A;  4TUI A;  3ZU0 A;  3RQZ A;  2DXN A;  4UT3 B;  2KKN A;  2WDD A;  2GJU A;  2Q8U A;  3GVE A;  1UTE A;  2WDE A;  1S70 A;  4KKZ A;  1T70 A;  2IE4 C;  5HPE A;  3FGA C;  4O4K A;  1S95 A;  3DSD A;  4DHL A;  3DSC A;  3EGG A;  1HPU A;  4ZVZ A;  3QG5 C;  1OID A;  3THO B;  4H1S A;  3H64 A;  3ICF A;  3CK2 A;  4FCX A;  4DSY A;  3E0J A;  2CV9 A;  1JK7 A;  4UT3 A;  3H66 A;  5DNY A;  2ZOA A;  3K7V C;  1FJM A;  2JOG A;  3HVQ A;  3QFK A;  4B2O A;  3IB8 A;  4WWL A;  1OIE A;  5GTU A;  2BDX A;  1U32 A; 
#chains in the Genus database with same CATH homology
 4FBW A;  4YKE A;  4I5L C;  3LL8 A;  2NYM C;  4V0W A;  2R17 A;  4IL1 A;  4XPN A;  1S3L A;  2IE3 C;  1Z2X A;  5IOH A;  2O8G A;  4TUG A;  1W24 A;  5JPF A;  3AV0 A;  4KBP A;  3P71 C;  3H61 A;  3PSN A;  2Z1A A;  2ZO9 B;  2Z72 A;  2QFP A;  4FBK A;  3KBP A;  5B8I A;  2ZBM A;  4MOV A;  1T71 A;  4DT2 A;  4G9J A;  1KBP A;  4O43 A;  3ZTV A;  4HD0 A;  3K7W C;  3C9F A;  1XM7 A;  2HY1 A;  4I5N C;  3RL4 A;  4ZX2 A;  3PSO A;  1QHW A;  4J6O A;  1XZW A;  4JA7 A;  4F0Z A;  2BQ8 X;  3TGH A;  3H63 A;  3RL3 A;  3THN A;  3IVD A;  1AUI A;  2AHD A;  4H2B A;  4O24 A;  4M0V A;  1SU1 A;  1TCO A;  1M63 A;  4NZV A;  3C5W C;  3QFN A;  4H1Y P;  2P6B A;  2WDF A;  1G5B A;  3DW8 C;  3E7B A;  5C1V A;  2HYO A;  2HYP A;  3IB7 A;  2YEQ A;  3EGH A;  4UT2 A;  2IAE C;  3H68 A;  2O8A A;  2QFR A;  3FLO A;  3N5U A;  2Z06 A;  3E7A A;  3IVE A;  1OI8 A;  3QFM A;  5EQV A;  1S3N A;  4Q7F A;  1QFC A;  2XMO A;  4LU9 A;  4V0V A;  1HP1 A;  3T1I A;  1Z2W A;  2A22 A;  4H2I A;  3QFO A;  4ORB A;  3H60 A;  4MP0 A;  1WAO 1;  2NYL C;  1S8E A;  3H62 B;  1MF8 A;  4FBQ A;  4ORA A;  2QJC A;  4V0X A;  1NNW A;  3H67 A;  2USH A;  4H2F A;  1S3M A;  1V73 A;  1UF3 A;  4H2G A;  5F3W A;  3D03 A;  3H69 A;  2DXL A;  2BCD A;  2YVT A;  3V4Y A;  4IYP C;  5JPE A;  4JA9 A;  4LTY A;  1II7 A;  2WDC A;  4O5G A;  3RL5 A;  5INB A;  1HO5 A;  4OR9 A;  4UWQ A;  3AUZ A;  5J28 A;  2NXF A;  1USH A;  4MOY A;  2NPP C;  3JYF A;  4ORC A;  5JJT A;  2DFJ A;  1IT6 A;  4LAC C;  1WAR A;  4TUI A;  3ZU0 A;  3RQZ A;  2DXN A;  4UT3 B;  2KKN A;  2WDD A;  2GJU A;  2Q8U A;  3GVE A;  1UTE A;  2WDE A;  1S70 A;  4KKZ A;  1T70 A;  2IE4 C;  5HPE A;  3FGA C;  4O4K A;  1S95 A;  3DSD A;  4DHL A;  3DSC A;  3EGG A;  1HPU A;  4ZVZ A;  3QG5 C;  1OID A;  3THO B;  4H1S A;  3H64 A;  3ICF A;  3CK2 A;  4FCX A;  4DSY A;  3E0J A;  2CV9 A;  1JK7 A;  4UT3 A;  3H66 A;  5DNY A;  2ZOA A;  3K7V C;  1FJM A;  2JOG A;  3HVQ A;  3QFK A;  4B2O A;  3IB8 A;  4WWL A;  1OIE A;  5GTU A;  2BDX A;  1U32 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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