2Q8UA

Crystal structure of mre11 from thermotoga maritima msb8 (tm1635) at 2.20 a resolution
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
329
structure length
308
Chain Sequence
b'HHHHHVINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIE'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Exonuclease, putative
publication title Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair.
pubmed doi rcsb
source organism Thermotoga maritima msb8
molecule tags Hydrolase
total genus 94
structure length 308
sequence length 329
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.160.210 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain DNA double-strand break repair nuclease 2q8uA02
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2q8uA01
3P71C 4TUIA 2JOGA 1TCOA 2BCDA 1WARA 3H61A 4XPNA 4F0ZA 4UT3A 5C1VA 3H62B 4LACC 4TUGA 1S8EA 4JA9A 1XZWA 4B2OA 2Z72A 3PSNA 2A22A 5GTUA 3QFMA 3E7BA 5HPEA 1QHWA 3FGAC 4FBQA 4H2IA 5B8IA 1MF8A 3PSOA 2IE3C 3E7AA 3H60A 3N5UA 4UT2A 1M63A 3IB8A 1HO5A 4H1YP 4O24A 1UTEA 1OIEA 5INBA 3H69A 3TGHA 1S3NA 1Z2XA 3QFOA 3RL3A 4O5GA 1G5BA 4MOVA 4KBPA 4IL1A 4KKZA 3EGHA 3H68A 5DNYA 1Z2WA 3K7VC 3EGGA 4I5LC 4H2BA 3H63A 4V0VA 4O43A 1UF3A 2QJCA 5JPFA 4M0VA 2WDEA 1SU1A 2ZBMA 4NZVA 2WDFA 5JPEA 2HYOA 3AV0A 4I5NC 1T71A 4H2FA 4V0XA 4FBKA 2NYLC 3QFKA 4FBWA 3JYFA 3V4YA 1WAO1 4ORBA 2NPPC 1S3MA 4FCXA 1NNWA 4LU9A 1S95A 3H66A 1XM7A 2CV9A 1V73A 4DHLA 2DFJA 2O8GA 4ORAA 2Z06A 3QG5C 3H64A 5IOHA 5EQVA 4WWLA 4MP0A 3IVDA 1USHA 2YVTA 1KBPA 4DT2A 4O4KA 1QFCA 1S70A 2WDDA 4OR9A 5J28A 3C9FA 2KKNA 3ZU0A 2AHDA 2WDCA 3IVEA 4HD0A 4ZVZA 4YKEA 4MOYA 3THOB 4JA7A 2USHA 3DSDA 2P6BA 1HP1A 2Q8UA 1FJMA 5JJTA 4IYPC 4G9JA 4LTYA 2BQ8X 3T1IA 4Q7FA 2IE4C 4J6OA 1AUIA 4H1SA 2Z1AA 3RQZA 3K7WC 4ORCA 2XMOA 3ZTVA 4ZX2A 3RL4A 1II7A 2BDXA 2QFPA 3IB7A 3KBPA 1S3LA 3QFNA 2HYPA 1T70A 3CK2A 1OI8A 2NYMC 4UWQA 2GJUA 3H67A 1HPUA 3DW8C 3GVEA 4DSYA 3AUZA 2IAEC 3LL8A 2R17A 4H2GA 4UT3B 2QFRA 2HY1A 3THNA 1JK7A 1IT6A 5F3WA 2O8AA 1OIDA 1U32A 3ICFA 2NXFA 1W24A 4V0WA 3HVQA 3RL5A 3DSCA 3C5WC
chains in the Genus database with same CATH superfamily
1ZU1A 1TCOA 3H61A 4XPNA 4DV2E 1FKAE 4BHBA 4ZYEA 1S8EA 3LLHA 4JA9A 4R2AA 1YPNA 2EOHA 5A6BD 3J81C 4MLVA 2A22A 4F9BB 1QHWA 4H2IA 2EL6A 3MSWA 1T4OA 2B9DA 4LF9E 2IE3C 3E7AA 2V86A 4I8OA 1BB8A 1MEYC 4H1YP 1UTEA 4NXME 2ODRC 1YFHA 4WSGA 3VK6A 5INBA 1IBKE 3JAMC 2JOBA 5T6JA 4R8OA 1ZBQA 1UHZA 4DR1E 5AE3A 5KL4A 5A2QC 2EM9A 4MLQA 4JI4E 4O5GA 4KKZA 1YUJA 5DNYA 2EQ0A 3JTZA 2KHXA 2JP9A 2UUBE 3EGGA 4I5LC 1QNTA 1WJPA 4M2ZA 4M0VA 2EPCA 1ZR9A 2GHFA 1XMQE 2WDFA 5JPEA 2I9IA 4BS9A 3AV0A 4JI5E 2LBSB 3JU0A 2LV2A 2EMGA 2NPPC 2CTDA 2WBSA 1S3MA 1Z1BA 4FCXA 2EOSA 1NNWA 1UILA 1V73A 4DHLA 2YTOA 2I13A 1L4SA 4ORAA 5AC4A 4DV3E 3T1YE 5LMNE 2YT4A 2YTGA 5IOHA 4IS1C 1X47A 2EPAA 3C4BA 3TQMA 2DLQA 2EM0A 5AASA 3J80C 4LFAE 1EH8A 4DV7E 4O4KA 4LF6E 2WDDA 4ZVZA 4YKEA 2YTJA 2HC5A 4X65E 1T38A 3DSDA 1HP1A 5JJTA 4R2CA 1KJKA 1N3GA 3ADIA 4LF7E 5A6KA 4F54A 4G9JA 4DMIA 2EMCA 2BQ8X 4J6OA 2YTEA 4JI8E 3F6HA 4R2QA 2LE2A 1AUIA 4BC7A 1PJSA 2NUEA 3HTXA 2PRTA 1KYQA 2HHHE 4ORCA 3OTOE 2EOOA 3IWBA 3ZTVA 2A25A 2N3GA 1GTKA 1PKPA 2R76A 4WXDA 5A6AA 1YUIA 1RQ0A 5A69A 2M7QA 2LTRA 2YTFA 3AUZA 3EPJA 1PDAA 5F3WA 3THNA 1T4LB 1DGCA 1JK7A 2EL5A 2YTDA 4GKJE 2O8AA 3BF2A 1X49A 1EH7A 3HPZA 5BR8E 4F9AB 2EMXA 4P78A 3VYXA 3P71C 1X6EA 4F6NA 2ENCA 1IBLE 3UK3C 2JOGA 4F0ZA 4UT3A 4BHCA 3H62B 2EMBA 2CT1A 1B69A 2HJJA 2B7VA 4DUZE 1PJQA 3M99B 3VYYA 4GKKE 4Q35B 5GTUA 3QFMA 2G7HA 2DSYA 3MHSC 3E7BA 2KONA 2UUAE 1YZ9A 5HPEA 2EMYA 2CPNA 1IMUA 2LJUA 1MF8A 4B3RE 1X6HA 2GPIA 1X3CA 3OMLA 2WCC3 2VE7C 1TF3A 4JI2E 1OIEA 3LMLA 1G2DC 2DGCA 4JV5E 2E5LE 3L00A 5FLXC 2YSPA 4DV4E 1O0WA 2M9AA 3QFOA 3RL3A 4R2EA 2JVAA 2DXLA 4KBPA 4IL1A 2MC5A 3EGHA 4N4RB 3H68A 2D9HA 1PJTA 2ZOAA 2EL4A 2EPNA 1J5EE 3K6QA 2UU9E 2E1MA 2EOEA 2UUCE 4DV6E 2QJCA 2EM8A 2WDEA 3DJWA 2K7IA 4M9VC 3J7AG 1SU1A 4NZVA 2ZBMA 2EM6A 2EN7A 2RSMA 2BB8A 1T71A 2EMKA 3BBGA 1X48A 3QFKA 2V88A 3KZZA 1WAO1 5KL5A 4B3ME 1YSAC 2EMWA 2JWOA 4LU9A 3H66A 1XM7A 2CV9A 1A1JA 2DFJA 1J26A 2O8GA 2E72A 2Z06A 2EPMX 2LT7A 2WBTA 2J7JA 5IXMB 2YRHA 2DB2A 1DI2A 2YZTA 4WYQB 1T4NA 5IWAE 4MP0A 2EMHA 1USHA 4ZYDA 2DMYA 3RMPA 2V83A 2JOXA 4YHHE 1HR0E 2RSIA 4OR9A 2EOMA 3C9FA 4X62E 3ZU0A 4R2SA 2MC6A 2WDCA 3IVEA 2EPZA 2RTXA 2YU8A 2EN2A 5AE2A 4DV5E 2YTQA 3HPSA 2EPLX 4BCAA 2P6BA 2JPAA 1FJMA 1F2IG 2GLIA 3HXLA 2EOYA 4RHBB 3VHTB 4AQYE 2L6MA 3ADGA 2WZOA 5IV8B 2ELZA 2Z1AA 4JI7E 2EPRA 2YWQA 4DKKA 2XMOA 1GQEA 4ZYGA 2V87A 3ADJA 2LTSA 1T39A 2BDXA 2ELYA 4LF4E 2QFPA 2EN3A 2VQFE 3C4TA 1UN6B 3J7Yp 2EN8A 5KL7A 1I94E 2NYMC 4HEIA 2EN1A 3H67A 2ODRD 1HPUA 2IAEC 2EOIA 2MDGA 1A1HA 1OIDA 2KOUA 2LJHA 1W24A 2NABA 3HVQA 3RL5A 3DSCA 3C5WC 2R1FA 1HNZE 3DF6A 1HNXE 2VRDA 2B7TA 1N32E 5C1VA 4HTGA 5ADZA 1XZWA 2JR1A 2LMZA 1ZAAC 2MKDA 3FLOA 2EN6A 5KL2A 2UXCE 2YRMA 3FGAC 4DR2E 1TF6A 3PSOA 2EOJA 1M63A 3IB8A 1HO5A 4O24A 2EORA 3H69A 1EH6A 1SR9A 4OX9E 3TGHA 2JXPA 4DR6E 1S3NA 1A1LA 2YTIA 4X64E 1YYKA 2JYAA 2LUQA 4F2JC 1G5BA 4OOGC 2EPOA 2K4VA 4R03A 4X9JA 1HNWE 4MOVA 1Z2WA 3F6GA 4BMJA 4NHRA 4H2BA 3H63A 4V0VA 4O43A 1UF3A 2RPCA 1JK2A 4DR4E 2EOXA 2EMAA 2EOZA 1G2FC 5LL6R 3C6MA 2M4IA 4JI3E 4FBWA 2ZM6E 3JYFA 4K0KE 2L2MA 2HGHA 3V4YA 4JI1E 2L3CA 2MKNA 3E0JA 4X66E 5LMUE 1DQ3A 4LFBE 1N36E 2EPUA 3MHHC 4WFTA 3H64A 3KWRA 2L3JA 4L8NA 2H36X 1ZBTA 5IT9C 5CFFE 3IVDA 2RS6A 2YVTA 3P1XA 2YU5A 1BBOA 4WX9A 5J28A 2EM3A 5TSEA 3H09A 4LF8E 2B3TB 2LO3A 1TN9A 2EZ6A 3BGHA 4Q28A 1FJGE 2DMIA 2USHA 2LUPB 2M1SA 4L5NC 1LLMC 1AH5A 2EM2A 4LTYA 1N34E 4WXCA 1XMOE 4Q7FA 2L92A 2EM5A 2YPNA 1GZ6A 2EQ3A 2RQLA 4B3TE 5AE1A 2L8TA 2EQ1A 3KZYA 1II7A 4J8ZA 2YTNA 3KBPA 2EWLA 1S3LA 2HYPA 5AC5A 2EM4A 2V85A 1T70A 2EP3A 3CK2A 1OI8A 4KHPE 2CSHA 2EMZA 2VF1A 1XNQE 2UXBE 4DSYA 3LL8A 2ENAA 4UT3B 1X5WA 2EMLA 2EOFA 1U32A 3ICFA 2NXFA 4V0WA 4JI0E 1A1KA 2EPXA 4TUIA 2YRKA 1WARA 2BCDA 2ZO9B 1IQSA 4TUGA 4LACC 1MGTA 2EE8A 5A6BA 4B2OA 1YYOA 4RH8A 2EM7A 2Z72A 3IWDA 3PSNA 4P7DA 5A6JA 1YYWA 1P47A 2FV4B 2N8XA 4WPYA 2DXNA 4FBQA 5B8IA 4JYAE 4R2DA 3H60A 3N5UA 4UT2A 4F9CB 3C6KA 1A1IA 2ADRA 1BBGA 4DR7E 2L33A 1N33E 4GEQB 1IBME 2DLKA 2IHR1 4M30A 1Z2XA 4IJDA 1RMDA 4NXNE 1UBDC 4X8WA 5LLQA 3K7VC 5JPFA 2EJ4A 2JY9A 4YY3E 1A1GA 2NA2A 4GZNC 4DV1E 2V89A 3ECRA 1NEIA 2HYOA 4I5NC 4H2FA 4V0XA 4FBKA 2NYLC 2L2KB 2LCEA 2EMIA 4ORBA 1WRJA 4DUYE 1S95A 4F6MA 2DRPA 2F8BA 4KWYA 2F4VE 3QG5C 5EQVA 4WWLA 3ZOQB 1NCSA 3EPKA 3ADLA 4KZSA 2EOQA 2FGGA 1KBPA 4DT2A 2NUFA 1WHQA 4WSPA 1WHNA 1QFCA 1S70A 1EKZA 2KKNA 4JI6E 2AHDA 4HD0A 1STUA 2L2NA 4MOYA 3THOB 4LFCE 4JA7A 3EPHA 2Q8UA 3BIDA 1RC7A 4IYPC 2EMFA 2V8QB 2DIXA 2LRSA 1AAYA 4ZYHA 3T1IA 3HQ1A 4R2PA 4DR3E 2IE4C 1SFEA 4DR5E 1QU6A 1WXRA 4H1SA 2EPKX 1JK1A 4LF5E 1X6FA 3T1HE 3RQZA 3K7WC 1A1FA 4ZX2A 3RL4A 3IWCA 3IB7A 3QFNA 2EN4A 2LVHA 2NUGA 2RS7A 4BBYA 5KL6A 3EQ1A 3D03A 2VQEE 1XNRE 3FIGA 2MDRA 1IQOA 2ENHA 4UWQA 4DV0E 2UXDE 2GJUA 4BC9A 3DW8C 3GVEA 2YEQA 2YTPA 4R2RA 4B3SE 2R17A 4H2GA 2WBUA 2EPPA 2FTXB 2QFRA 4FK5C 2HY1A 1IT6A 5KL3A 2BBGA 3EPLA 2YSOA 2N3HA
chains in the Genus database with same CATH topology
3P71C 4TUIA 2JOGA 1TCOA 2BCDA 1WARA 2ZO9B 3H61A 4XPNA 4F0ZA 4UT3A 5C1VA 3H62B 4LACC 4TUGA 1S8EA 4JA9A 1XZWA 4B2OA 2Z72A 3FLOA 3PSNA 2A22A 5GTUA 3QFMA 3E7BA 5HPEA 1QHWA 2DXNA 3FGAC 4FBQA 4H2IA 5B8IA 1MF8A 3PSOA 2IE3C 3E7AA 3H60A 3N5UA 4UT2A 1M63A 3IB8A 1HO5A 4H1YP 4O24A 1UTEA 1OIEA 5INBA 3H69A 3TGHA 1S3NA 1Z2XA 3QFOA 3RL3A 4O5GA 1G5BA 2DXLA 4MOVA 4KBPA 4IL1A 4KKZA 3EGHA 3H68A 5DNYA 1Z2WA 2ZOAA 3K7VC 3EGGA 4I5LC 4H2BA 3H63A 4V0VA 4O43A 1UF3A 2QJCA 5JPFA 4M0VA 2WDEA 1SU1A 2ZBMA 4NZVA 2WDFA 5JPEA 2HYOA 3AV0A 4I5NC 1T71A 4H2FA 4V0XA 4FBKA 2NYLC 3QFKA 4FBWA 3JYFA 3V4YA 1WAO1 4ORBA 2NPPC 1S3MA 3E0JA 4FCXA 1NNWA 4LU9A 1S95A 3H66A 1XM7A 2CV9A 1V73A 4DHLA 2DFJA 2O8GA 4ORAA 2Z06A 3QG5C 3H64A 5IOHA 5EQVA 4WWLA 4MP0A 3IVDA 1USHA 2YVTA 1KBPA 4DT2A 4O4KA 1QFCA 1S70A 2WDDA 4OR9A 5J28A 3C9FA 2KKNA 3ZU0A 4HD0A 2AHDA 2WDCA 3IVEA 4ZVZA 4YKEA 4MOYA 3THOB 4JA7A 3DSDA 2USHA 2P6BA 1HP1A 2Q8UA 1FJMA 5JJTA 4IYPC 4G9JA 4LTYA 2BQ8X 3T1IA 4Q7FA 2IE4C 4J6OA 1AUIA 4H1SA 2Z1AA 3RQZA 3K7WC 4ORCA 2XMOA 3ZTVA 4ZX2A 3RL4A 1II7A 2BDXA 2QFPA 3IB7A 3KBPA 1S3LA 3QFNA 2HYPA 3D03A 1T70A 3CK2A 1OI8A 2NYMC 4UWQA 2GJUA 3H67A 1HPUA 3DW8C 3GVEA 2YEQA 3AUZA 4DSYA 2IAEC 3LL8A 2R17A 4H2GA 4UT3B 2QFRA 2HY1A 3THNA 1JK7A 1IT6A 5F3WA 2O8AA 1OIDA 1U32A 3ICFA 2NXFA 1W24A 4V0WA 3HVQA 3RL5A 3DSCA 3C5WC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P71 C;  4TUI A;  2JOG A;  1TCO A;  2BCD A;  1WAR A;  3H61 A;  4XPN A;  4F0Z A;  4UT3 A;  5C1V A;  3H62 B;  4LAC C;  4TUG A;  1S8E A;  4JA9 A;  1XZW A;  4B2O A;  2Z72 A;  3PSN A;  2A22 A;  5GTU A;  3QFM A;  3E7B A;  5HPE A;  1QHW A;  3FGA C;  4FBQ A;  4H2I A;  5B8I A;  1MF8 A;  3PSO A;  2IE3 C;  3E7A A;  3H60 A;  3N5U A;  4UT2 A;  1M63 A;  3IB8 A;  1HO5 A;  4H1Y P;  4O24 A;  1UTE A;  1OIE A;  5INB A;  3H69 A;  3TGH A;  1S3N A;  1Z2X A;  3QFO A;  3RL3 A;  4O5G A;  1G5B A;  4MOV A;  4KBP A;  4IL1 A;  4KKZ A;  3EGH A;  3H68 A;  5DNY A;  1Z2W A;  3K7V C;  3EGG A;  4I5L C;  4H2B A;  3H63 A;  4V0V A;  4O43 A;  1UF3 A;  2QJC A;  5JPF A;  4M0V A;  2WDE A;  1SU1 A;  2ZBM A;  4NZV A;  2WDF A;  5JPE A;  2HYO A;  3AV0 A;  4I5N C;  1T71 A;  4H2F A;  4V0X A;  4FBK A;  2NYL C;  3QFK A;  4FBW A;  3JYF A;  3V4Y A;  1WAO 1;  4ORB A;  2NPP C;  1S3M A;  4FCX A;  1NNW A;  4LU9 A;  1S95 A;  3H66 A;  1XM7 A;  2CV9 A;  1V73 A;  4DHL A;  2DFJ A;  2O8G A;  4ORA A;  2Z06 A;  3QG5 C;  3H64 A;  5IOH A;  5EQV A;  4WWL A;  4MP0 A;  3IVD A;  1USH A;  2YVT A;  1KBP A;  4DT2 A;  4O4K A;  1QFC A;  1S70 A;  2WDD A;  4OR9 A;  5J28 A;  3C9F A;  2KKN A;  3ZU0 A;  2AHD A;  2WDC A;  3IVE A;  4HD0 A;  4ZVZ A;  4YKE A;  4MOY A;  3THO B;  4JA7 A;  2USH A;  3DSD A;  2P6B A;  1HP1 A;  2Q8U A;  1FJM A;  5JJT A;  4IYP C;  4G9J A;  4LTY A;  2BQ8 X;  3T1I A;  4Q7F A;  2IE4 C;  4J6O A;  1AUI A;  4H1S A;  2Z1A A;  3RQZ A;  3K7W C;  4ORC A;  2XMO A;  3ZTV A;  4ZX2 A;  3RL4 A;  1II7 A;  2BDX A;  2QFP A;  3IB7 A;  3KBP A;  1S3L A;  3QFN A;  2HYP A;  1T70 A;  3CK2 A;  1OI8 A;  2NYM C;  4UWQ A;  2GJU A;  3H67 A;  1HPU A;  3DW8 C;  3GVE A;  4DSY A;  3AUZ A;  2IAE C;  3LL8 A;  2R17 A;  4H2G A;  4UT3 B;  2QFR A;  2HY1 A;  3THN A;  1JK7 A;  1IT6 A;  5F3W A;  2O8A A;  1OID A;  1U32 A;  3ICF A;  2NXF A;  1W24 A;  4V0W A;  3HVQ A;  3RL5 A;  3DSC A;  3C5W C; 
#chains in the Genus database with same CATH topology
 1ZU1 A;  1TCO A;  3H61 A;  4XPN A;  4DV2 E;  1FKA E;  4BHB A;  4ZYE A;  1S8E A;  3LLH A;  4JA9 A;  4R2A A;  1YPN A;  2EOH A;  5A6B D;  3J81 C;  4MLV A;  2A22 A;  4F9B B;  1QHW A;  4H2I A;  2EL6 A;  3MSW A;  1T4O A;  2B9D A;  4LF9 E;  2IE3 C;  3E7A A;  2V86 A;  4I8O A;  1BB8 A;  1MEY C;  4H1Y P;  1UTE A;  4NXM E;  2ODR C;  1YFH A;  4WSG A;  3VK6 A;  5INB A;  1IBK E;  3JAM C;  2JOB A;  5T6J A;  4R8O A;  1ZBQ A;  1UHZ A;  4DR1 E;  5AE3 A;  5KL4 A;  5A2Q C;  2EM9 A;  4MLQ A;  4JI4 E;  4O5G A;  4KKZ A;  1YUJ A;  5DNY A;  2EQ0 A;  3JTZ A;  2KHX A;  2JP9 A;  2UUB E;  3EGG A;  4I5L C;  1QNT A;  1WJP A;  4M2Z A;  4M0V A;  2EPC A;  1ZR9 A;  2GHF A;  1XMQ E;  2WDF A;  5JPE A;  2I9I A;  4BS9 A;  3AV0 A;  4JI5 E;  2LBS B;  3JU0 A;  2LV2 A;  2EMG A;  2NPP C;  2CTD A;  2WBS A;  1S3M A;  1Z1B A;  4FCX A;  2EOS A;  1NNW A;  1UIL A;  1V73 A;  4DHL A;  2YTO A;  2I13 A;  1L4S A;  4ORA A;  5AC4 A;  4DV3 E;  3T1Y E;  5LMN E;  2YT4 A;  2YTG A;  5IOH A;  4IS1 C;  1X47 A;  2EPA A;  3C4B A;  3TQM A;  2DLQ A;  2EM0 A;  5AAS A;  3J80 C;  4LFA E;  1EH8 A;  4DV7 E;  4O4K A;  4LF6 E;  2WDD A;  4ZVZ A;  4YKE A;  2YTJ A;  2HC5 A;  4X65 E;  1T38 A;  3DSD A;  1HP1 A;  5JJT A;  4R2C A;  1KJK A;  1N3G A;  3ADI A;  4LF7 E;  5A6K A;  4F54 A;  4G9J A;  4DMI A;  2EMC A;  2BQ8 X;  4J6O A;  2YTE A;  4JI8 E;  3F6H A;  4R2Q A;  2LE2 A;  1AUI A;  4BC7 A;  1PJS A;  2NUE A;  3HTX A;  2PRT A;  1KYQ A;  2HHH E;  4ORC A;  3OTO E;  2EOO A;  3IWB A;  3ZTV A;  2A25 A;  2N3G A;  1GTK A;  1PKP A;  2R76 A;  4WXD A;  5A6A A;  1YUI A;  1RQ0 A;  5A69 A;  2M7Q A;  2LTR A;  2YTF A;  3AUZ A;  3EPJ A;  1PDA A;  5F3W A;  3THN A;  1T4L B;  1DGC A;  1JK7 A;  2EL5 A;  2YTD A;  4GKJ E;  2O8A A;  3BF2 A;  1X49 A;  1EH7 A;  3HPZ A;  5BR8 E;  4F9A B;  2EMX A;  4P78 A;  3VYX A;  3P71 C;  1X6E A;  4F6N A;  2ENC A;  1IBL E;  3UK3 C;  2JOG A;  4F0Z A;  4UT3 A;  4BHC A;  3H62 B;  2EMB A;  2CT1 A;  1B69 A;  2HJJ A;  2B7V A;  4DUZ E;  1PJQ A;  3M99 B;  3VYY A;  4GKK E;  4Q35 B;  5GTU A;  3QFM A;  2G7H A;  2DSY A;  3MHS C;  3E7B A;  2KON A;  2UUA E;  1YZ9 A;  5HPE A;  2EMY A;  2CPN A;  1IMU A;  2LJU A;  1MF8 A;  4B3R E;  1X6H A;  2GPI A;  1X3C A;  3OML A;  2WCC 3;  2VE7 C;  1TF3 A;  4JI2 E;  1OIE A;  3LML A;  1G2D C;  2DGC A;  4JV5 E;  2E5L E;  3L00 A;  5FLX C;  2YSP A;  4DV4 E;  1O0W A;  2M9A A;  3QFO A;  3RL3 A;  4R2E A;  2JVA A;  2DXL A;  4KBP A;  4IL1 A;  2MC5 A;  3EGH A;  4N4R B;  3H68 A;  2D9H A;  1PJT A;  2ZOA A;  2EL4 A;  2EPN A;  1J5E E;  3K6Q A;  2UU9 E;  2E1M A;  2EOE A;  2UUC E;  4DV6 E;  2QJC A;  2EM8 A;  2WDE A;  3DJW A;  2K7I A;  4M9V C;  3J7A G;  1SU1 A;  4NZV A;  2ZBM A;  2EM6 A;  2EN7 A;  2RSM A;  2BB8 A;  1T71 A;  2EMK A;  3BBG A;  1X48 A;  3QFK A;  2V88 A;  3KZZ A;  1WAO 1;  5KL5 A;  4B3M E;  1YSA C;  2EMW A;  2JWO A;  4LU9 A;  3H66 A;  1XM7 A;  2CV9 A;  1A1J A;  2DFJ A;  1J26 A;  2O8G A;  2E72 A;  2Z06 A;  2EPM X;  2LT7 A;  2WBT A;  2J7J A;  5IXM B;  2YRH A;  2DB2 A;  1DI2 A;  2YZT A;  4WYQ B;  1T4N A;  5IWA E;  4MP0 A;  2EMH A;  1USH A;  4ZYD A;  2DMY A;  3RMP A;  2V83 A;  2JOX A;  4YHH E;  1HR0 E;  2RSI A;  4OR9 A;  2EOM A;  3C9F A;  4X62 E;  3ZU0 A;  4R2S A;  2MC6 A;  2WDC A;  3IVE A;  2EPZ A;  2RTX A;  2YU8 A;  2EN2 A;  5AE2 A;  4DV5 E;  2YTQ A;  3HPS A;  2EPL X;  4BCA A;  2P6B A;  2JPA A;  1FJM A;  1F2I G;  2GLI A;  3HXL A;  2EOY A;  4RHB B;  3VHT B;  4AQY E;  2L6M A;  3ADG A;  2WZO A;  5IV8 B;  2ELZ A;  2Z1A A;  4JI7 E;  2EPR A;  2YWQ A;  4DKK A;  2XMO A;  1GQE A;  4ZYG A;  2V87 A;  3ADJ A;  2LTS A;  1T39 A;  2BDX A;  2ELY A;  4LF4 E;  2QFP A;  2EN3 A;  2VQF E;  3C4T A;  1UN6 B;  3J7Y p;  2EN8 A;  5KL7 A;  1I94 E;  2NYM C;  4HEI A;  2EN1 A;  3H67 A;  2ODR D;  1HPU A;  2IAE C;  2EOI A;  2MDG A;  1A1H A;  1OID A;  2KOU A;  2LJH A;  1W24 A;  2NAB A;  3HVQ A;  3RL5 A;  3DSC A;  3C5W C;  2R1F A;  1HNZ E;  3DF6 A;  1HNX E;  2VRD A;  2B7T A;  1N32 E;  5C1V A;  4HTG A;  5ADZ A;  1XZW A;  2JR1 A;  2LMZ A;  1ZAA C;  2MKD A;  3FLO A;  2EN6 A;  5KL2 A;  2UXC E;  2YRM A;  3FGA C;  4DR2 E;  1TF6 A;  3PSO A;  2EOJ A;  1M63 A;  3IB8 A;  1HO5 A;  4O24 A;  2EOR A;  3H69 A;  1EH6 A;  1SR9 A;  4OX9 E;  3TGH A;  2JXP A;  4DR6 E;  1S3N A;  1A1L A;  2YTI A;  4X64 E;  1YYK A;  2JYA A;  2LUQ A;  4F2J C;  1G5B A;  4OOG C;  2EPO A;  2K4V A;  4R03 A;  4X9J A;  1HNW E;  4MOV A;  1Z2W A;  3F6G A;  4BMJ A;  4NHR A;  4H2B A;  3H63 A;  4V0V A;  4O43 A;  1UF3 A;  2RPC A;  1JK2 A;  4DR4 E;  2EOX A;  2EMA A;  2EOZ A;  1G2F C;  5LL6 R;  3C6M A;  2M4I A;  4JI3 E;  4FBW A;  2ZM6 E;  3JYF A;  4K0K E;  2L2M A;  2HGH A;  3V4Y A;  4JI1 E;  2L3C A;  2MKN A;  3E0J A;  4X66 E;  5LMU E;  1DQ3 A;  4LFB E;  1N36 E;  2EPU A;  3MHH C;  4WFT A;  3H64 A;  3KWR A;  2L3J A;  4L8N A;  2H36 X;  1ZBT A;  5IT9 C;  5CFF E;  3IVD A;  2RS6 A;  2YVT A;  3P1X A;  2YU5 A;  1BBO A;  4WX9 A;  5J28 A;  2EM3 A;  5TSE A;  3H09 A;  4LF8 E;  2B3T B;  2LO3 A;  1TN9 A;  2EZ6 A;  3BGH A;  4Q28 A;  1FJG E;  2DMI A;  2USH A;  2LUP B;  2M1S A;  4L5N C;  1LLM C;  1AH5 A;  2EM2 A;  4LTY A;  1N34 E;  4WXC A;  1XMO E;  4Q7F A;  2L92 A;  2EM5 A;  2YPN A;  1GZ6 A;  2EQ3 A;  2RQL A;  4B3T E;  5AE1 A;  2L8T A;  2EQ1 A;  3KZY A;  1II7 A;  4J8Z A;  2YTN A;  3KBP A;  2EWL A;  1S3L A;  2HYP A;  5AC5 A;  2EM4 A;  2V85 A;  1T70 A;  2EP3 A;  3CK2 A;  1OI8 A;  4KHP E;  2CSH A;  2EMZ A;  2VF1 A;  1XNQ E;  2UXB E;  4DSY A;  3LL8 A;  2ENA A;  4UT3 B;  1X5W A;  2EML A;  2EOF A;  1U32 A;  3ICF A;  2NXF A;  4V0W A;  4JI0 E;  1A1K A;  2EPX A;  4TUI A;  2YRK A;  1WAR A;  2BCD A;  2ZO9 B;  1IQS A;  4TUG A;  4LAC C;  1MGT A;  2EE8 A;  5A6B A;  4B2O A;  1YYO A;  4RH8 A;  2EM7 A;  2Z72 A;  3IWD A;  3PSN A;  4P7D A;  5A6J A;  1YYW A;  1P47 A;  2FV4 B;  2N8X A;  4WPY A;  2DXN A;  4FBQ A;  5B8I A;  4JYA E;  4R2D A;  3H60 A;  3N5U A;  4UT2 A;  4F9C B;  3C6K A;  1A1I A;  2ADR A;  1BBG A;  4DR7 E;  2L33 A;  1N33 E;  4GEQ B;  1IBM E;  2DLK A;  2IHR 1;  4M30 A;  1Z2X A;  4IJD A;  1RMD A;  4NXN E;  1UBD C;  4X8W A;  5LLQ A;  3K7V C;  5JPF A;  2EJ4 A;  2JY9 A;  4YY3 E;  1A1G A;  2NA2 A;  4GZN C;  4DV1 E;  2V89 A;  3ECR A;  1NEI A;  2HYO A;  4I5N C;  4H2F A;  4V0X A;  4FBK A;  2NYL C;  2L2K B;  2LCE A;  2EMI A;  4ORB A;  1WRJ A;  4DUY E;  1S95 A;  4F6M A;  2DRP A;  2F8B A;  4KWY A;  2F4V E;  3QG5 C;  5EQV A;  4WWL A;  3ZOQ B;  1NCS A;  3EPK A;  3ADL A;  4KZS A;  2EOQ A;  2FGG A;  1KBP A;  4DT2 A;  2NUF A;  1WHQ A;  4WSP A;  1WHN A;  1QFC A;  1S70 A;  1EKZ A;  2KKN A;  4JI6 E;  2AHD A;  4HD0 A;  1STU A;  2L2N A;  4MOY A;  3THO B;  4LFC E;  4JA7 A;  3EPH A;  2Q8U A;  3BID A;  1RC7 A;  4IYP C;  2EMF A;  2V8Q B;  2DIX A;  2LRS A;  1AAY A;  4ZYH A;  3T1I A;  3HQ1 A;  4R2P A;  4DR3 E;  2IE4 C;  1SFE A;  4DR5 E;  1QU6 A;  1WXR A;  4H1S A;  2EPK X;  1JK1 A;  4LF5 E;  1X6F A;  3T1H E;  3RQZ A;  3K7W C;  1A1F A;  4ZX2 A;  3RL4 A;  3IWC A;  3IB7 A;  3QFN A;  2EN4 A;  2LVH A;  2NUG A;  2RS7 A;  4BBY A;  5KL6 A;  3EQ1 A;  3D03 A;  2VQE E;  1XNR E;  3FIG A;  2MDR A;  1IQO A;  2ENH A;  4UWQ A;  4DV0 E;  2UXD E;  2GJU A;  4BC9 A;  3DW8 C;  3GVE A;  2YEQ A;  2YTP A;  4R2R A;  4B3S E;  2R17 A;  4H2G A;  2WBU A;  2EPP A;  2FTX B;  2QFR A;  4FK5 C;  2HY1 A;  1IT6 A;  5KL3 A;  2BBG A;  3EPL A;  2YSO A;  2N3H A; 
#chains in the Genus database with same CATH homology
 3P71 C;  4TUI A;  2JOG A;  1TCO A;  2BCD A;  1WAR A;  2ZO9 B;  3H61 A;  4XPN A;  4F0Z A;  4UT3 A;  5C1V A;  3H62 B;  4LAC C;  4TUG A;  1S8E A;  4JA9 A;  1XZW A;  4B2O A;  2Z72 A;  3FLO A;  3PSN A;  2A22 A;  5GTU A;  3QFM A;  3E7B A;  5HPE A;  1QHW A;  2DXN A;  3FGA C;  4FBQ A;  4H2I A;  5B8I A;  1MF8 A;  3PSO A;  2IE3 C;  3E7A A;  3H60 A;  3N5U A;  4UT2 A;  1M63 A;  3IB8 A;  1HO5 A;  4H1Y P;  4O24 A;  1UTE A;  1OIE A;  5INB A;  3H69 A;  3TGH A;  1S3N A;  1Z2X A;  3QFO A;  3RL3 A;  4O5G A;  1G5B A;  2DXL A;  4MOV A;  4KBP A;  4IL1 A;  4KKZ A;  3EGH A;  3H68 A;  5DNY A;  1Z2W A;  2ZOA A;  3K7V C;  3EGG A;  4I5L C;  4H2B A;  3H63 A;  4V0V A;  4O43 A;  1UF3 A;  2QJC A;  5JPF A;  4M0V A;  2WDE A;  1SU1 A;  2ZBM A;  4NZV A;  2WDF A;  5JPE A;  2HYO A;  3AV0 A;  4I5N C;  1T71 A;  4H2F A;  4V0X A;  4FBK A;  2NYL C;  3QFK A;  4FBW A;  3JYF A;  3V4Y A;  1WAO 1;  4ORB A;  2NPP C;  1S3M A;  3E0J A;  4FCX A;  1NNW A;  4LU9 A;  1S95 A;  3H66 A;  1XM7 A;  2CV9 A;  1V73 A;  4DHL A;  2DFJ A;  2O8G A;  4ORA A;  2Z06 A;  3QG5 C;  3H64 A;  5IOH A;  5EQV A;  4WWL A;  4MP0 A;  3IVD A;  1USH A;  2YVT A;  1KBP A;  4DT2 A;  4O4K A;  1QFC A;  1S70 A;  2WDD A;  4OR9 A;  5J28 A;  3C9F A;  2KKN A;  3ZU0 A;  4HD0 A;  2AHD A;  2WDC A;  3IVE A;  4ZVZ A;  4YKE A;  4MOY A;  3THO B;  4JA7 A;  3DSD A;  2USH A;  2P6B A;  1HP1 A;  2Q8U A;  1FJM A;  5JJT A;  4IYP C;  4G9J A;  4LTY A;  2BQ8 X;  3T1I A;  4Q7F A;  2IE4 C;  4J6O A;  1AUI A;  4H1S A;  2Z1A A;  3RQZ A;  3K7W C;  4ORC A;  2XMO A;  3ZTV A;  4ZX2 A;  3RL4 A;  1II7 A;  2BDX A;  2QFP A;  3IB7 A;  3KBP A;  1S3L A;  3QFN A;  2HYP A;  3D03 A;  1T70 A;  3CK2 A;  1OI8 A;  2NYM C;  4UWQ A;  2GJU A;  3H67 A;  1HPU A;  3DW8 C;  3GVE A;  2YEQ A;  3AUZ A;  4DSY A;  2IAE C;  3LL8 A;  2R17 A;  4H2G A;  4UT3 B;  2QFR A;  2HY1 A;  3THN A;  1JK7 A;  1IT6 A;  5F3W A;  2O8A A;  1OID A;  1U32 A;  3ICF A;  2NXF A;  1W24 A;  4V0W A;  3HVQ A;  3RL5 A;  3DSC A;  3C5W C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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