2Q8UA

Crystal structure of mre11 from thermotoga maritima msb8 (tm1635) at 2.20 a resolution
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
329
structure length
308
Chain Sequence
HHHHHVINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Exonuclease, putative
publication title Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair.
pubmed doi rcsb
source organism Thermotoga maritima msb8
molecule tags Hydrolase
total genus 94
structure length 308
sequence length 329
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.160.210 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain DNA double-strand break repair nuclease 2q8uA02
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2q8uA01
4G9JA 3ZU0A 4B2OA 1TCOA 1KBPA 3H60A 1MF8A 3EGHA 3H63A 4WWLA 2Z06A 4V0WA 3AV0A 2QFRA 3QFKA 4FBWA 4F0ZA 1FJMA 3E7BA 3RQZA 4O43A 3EGGA 3H61A 2A22A 5B8IA 1UTEA 1NNWA 3C5WC 2Q8UA 4LU9A 1WAO1 4YKEA 5IOHA 3K7WC 1XM7A 3IB8A 4NZVA 3IVDA 4MOVA 4ORCA 4HD0A 3KBPA 4LTYA 1USHA 4O4KA 1S3NA 2XMOA 4ZX2A 4H2IA 2BDXA 4OR9A 4H1YP 2GJUA 4H2GA 5GTUA 4H1SA 3T1IA 4J6OA 3RL4A 2CV9A 4UT3A 3IB7A 1IT6A 3K7VC 2JOGA 4UT3B 4V0XA 1G5BA 2P6BA 1T70A 3HVQA 2YVTA 1OIDA 1Z2WA 3H62B 3FGAC 3DW8C 5INBA 4IL1A 5HPEA 5JJTA 2AHDA 5JPFA 2R17A 4JA9A 4UT2A 3RL5A 5EQVA 2Z1AA 1QHWA 4O24A 2WDDA 4V0VA 1Z2XA 3IVEA 4UWQA 1SU1A 3LL8A 2WDCA 4IYPC 4XPNA 1XZWA 3H67A 4FBKA 2BCDA 2IE4C 3TGHA 2IE3C 1V73A 3P71C 2HYOA 4TUGA 4TUIA 3H68A 3AUZA 1JK7A 3V4YA 4H2FA 1UF3A 2HY1A 3E7AA 4ORAA 4MOYA 4O5GA 2WDFA 3QFOA 2O8GA 2WDEA 3C9FA 4M0VA 3PSNA 3QG5C 1II7A 3QFMA 4I5LC 4LACC 2Z72A 4Q7FA 2NYLC 4KBPA 3CK2A 4H2BA 2USHA 3GVEA 2ZBMA 2NYMC 3ICFA 4MP0A 1S70A 3THNA 2NPPC 4DHLA 4KKZA 4DSYA 2NXFA 2DFJA 1M63A 5C1VA 3DSDA 1HO5A 1AUIA 1OI8A 1U32A 4FCXA 2KKNA 3PSOA 5DNYA 1S3LA 1HP1A 1T71A 5F3WA 4ZVZA 2O8AA 4I5NC 1HPUA 1W24A 3JYFA 4FBQA 5J28A 3H66A 2BQ8X 1WARA 3QFNA 2QFPA 1S8EA 3H69A 4JA7A 4ORBA 4DT2A 3THOB 3DSCA 1S3MA 2IAEC 3RL3A 5JPEA 1OIEA 3ZTVA 1S95A 3N5UA 1QFCA 2QJCA 2HYPA 3H64A
chains in the Genus database with same CATH superfamily
1MGTA 4DR4E 2EPOA 2LJHA 1XNRE 5CFFE 4M30A 4B3SE 1MF8A 3EGHA 3H63A 2K4VA 2YTGA 4WWLA 4F9BB 2WBTA 5A69A 1X6FA 2EOQA 2YU8A 2UXDE 4FBWA 1GZ6A 3C4BA 3RQZA 5LMUE 3H61A 2A22A 1BB8A 1NNWA 2EQ0A 4L8NA 1AAYA 1ZU1A 4I8OA 1A1IA 2HGHA 2LUPB 4ORCA 1LLMC 2EMFA 3K6QA 2I9IA 4O4KA 1S3NA 3HPSA 2KOUA 2DMYA 3EPLA 2L2MA 2RQLA 4JI3E 4M2ZA 4DV3E 4WYQB 5KL2A 4H2GA 2EORA 2WBUA 5AE2A 4H1SA 4UT3A 2EE8A 2VE7C 2ADRA 2YRHA 2J7JA 1DQ3A 4DV5E 1IT6A 3IB7A 5LMNE 3K7VC 2JOGA 4UT3B 4V0XA 2KONA 2B3TB 1EH6A 2DLKA 2EOHA 2EM3A 1L4SA 2RTXA 1YFHA 3HVQA 2EMIA 3LMLA 4X8WA 1A1GA 2ZOAA 3H62B 2LT7A 4WXDA 2LMZA 2HC5A 3DW8C 1WJPA 4JA9A 4UT2A 3RL5A 4BCAA 2NUGA 1QHWA 1TN9A 4GKJE 4V0VA 2BB8A 4BMJA 4R8OA 2YTFA 4JI0E 4UWQA 2ENCA 4JI8E 1HNWE 2VRDA 1STUA 2B7VA 1X49A 2EM9A 4NXME 1ZBQA 2HHHE 5FLXC 4TUGA 3TGHA 2HYOA 2EPAA 4P78A 3FIGA 2RSMA 1XMOE 3E7AA 4MOYA 4O5GA 1N33E 3QFOA 2WDEA 2ENAA 3J81C 1EH8A 4DR2E 2EPNA 2RS6A 1EH7A 3CK2A 2YTNA 1BBOA 2MKNA 2YSPA 2E5LE 4B3RE 1IQOA 1UHZA 2DFJA 2V83A 1M63A 2L33A 3MSWA 1IQSA 4WSGA 5DNYA 5KL7A 2L3JA 2ZM6E 5F3WA 3BGHA 2JY9A 1X3CA 2H36X 2R76A 2B7TA 2LBSB 1W24A 3JYFA 4DV1E 4WXCA 5J28A 1WARA 3QFNA 4HEIA 1S8EA 2QFPA 4DV7E 4ORBA 2YPNA 4LF6E 1HNXE 4DT2A 3DSCA 4YY3E 1S3MA 3RL3A 5AE3A 1OIEA 4OOGC 2FTXB 4WPYA 1X6EA 5A6JA 2HYPA 2EPUA 4MLQA 4LACC 1PDAA 4LF7E 2EMGA 4G9JA 3ZU0A 4F9CB 4NXNE 3H60A 2LVHA 2N3GA 2MDRA 2EPZA 4DV6E 4V0WA 2QFRA 2I13A 4R2CA 2YTOA 4O43A 4NHRA 5LL6R 4R2PA 1UTEA 2EOIA 3P1XA 2JVAA 2B9DA 2F8BA 2VF1A 1WAO1 2V8QB 2L3CA 2LV2A 3ADGA 1XM7A 3IB8A 3C6KA 1A1HA 4HD0A 4LTYA 1A1LA 4IJDA 4KZSA 2BDXA 3E0JA 4OR9A 3JAMC 5IV8B 2V85A 2WCC3 2EOYA 4R2SA 3T1IA 1PKPA 4J6OA 1J26A 2CV9A 1RQ0A 3C4TA 4BC9A 1TF6A 1DI2A 5KL6A 4KHPE 1G5BA 3MHSC 4B3TE 4WX9A 1T70A 1HNZE 4JI1E 1Z2WA 1YPNA 2WBSA 5INBA 2EPLX 2JP9A 2EMYA 5JJTA 1N3GA 2NUEA 2E72A 1T4LB 2WDDA 5AE1A 2V88A 2JYAA 1Z2XA 2EPCA 4R03A 1SU1A 3LL8A 3LLHA 2EPMX 1N32E 2V86A 2LO3A 4FBKA 2ODRD 1V73A 4TUIA 3H68A 1I94E 3T1YE 2EOFA 2DRPA 3AUZA 1JK7A 1EKZA 2HY1A 4ORAA 2EPKX 3C9FA 4F6NA 2EMCA 2L6MA 1II7A 2YEQA 3QFMA 2EN1A 2YSOA 2RSIA 4GEQB 3ADLA 2EWLA 3KZYA 4R2RA 3EPHA 4K0KE 4Q7FA 1T39A 2GPIA 1PJTA 4H2BA 2ODRC 1A1JA 2ZBMA 2HJJA 1S70A 2NPPC 1YUJA 2L8TA 1YYOA 2LTRA 4JYAE 2UXBE 4BS9A 1AUIA 2YTJA 2UUBE 4Q28A 3PSOA 4MLVA 2LCEA 3FLOA 4JI6E 1X6HA 2JOXA 1HPUA 2EM2A 4ZYEA 1G2FC 3JTZA 4FBQA 1X47A 2EN2A 2EQ3A 2YZTA 3BF2A 2EOZA 1YYKA 3H69A 5KL5A 1ZBTA 2IAEC 5JPEA 3ADJA 1B69A 3ZTVA 3HPZA 1P47A 2EN8A 2CPNA 1XMQE 2DXNA 3N5UA 2QJCA 2D9HA 2EOSA 3EPKA 4DUZE 3EQ1A 1WRJA 2L2NA 1UN6B 2L92A 3DF6A 5BR8E 2M7QA 1KBPA 2EOEA 2DSYA 3C6MA 1YUIA 2MDGA 2EZ6A 1O0WA 2KHXA 4JI2E 3F6HA 3AV0A 5AASA 3QFKA 1BBGA 2EMAA 4F0ZA 3E7BA 2ELYA 2NUFA 1PJSA 5B8IA 4BHCA 2FV4B 2EM7A 2EMZA 2Q8UA 2EM6A 4R2AA 2JWOA 4FK5C 4R2EA 1WHQA 3K7WC 3ZOQB 4X66E 4KWYA 4DV0E 2UUAE 4GZNC 4NZVA 3IVDA 4MOVA 4Q35B 2MKDA 5IWAE 3KBPA 4L5NC 5AC5A 1USHA 2XMOA 1GTKA 2EPRA 3EPJA 4H2IA 4ZX2A 4AQYE 2BBGA 4X64E 1UBDC 2GJUA 2LUQA 1T38A 3HTXA 5GTUA 2EOOA 5A6KA 2N8XA 1FJGE 3RL4A 4WFTA 4F54A 2A25A 2JXPA 1ZAAC 4M9VC 2YWQA 4DR3E 2P6BA 4ZYHA 1G2DC 2L2KB 1IBKE 5TSEA 5HPEA 1IBLE 2AHDA 1YZ9A 2R17A 3KWRA 5EQVA 1QU6A 4O24A 2EM5A 3J7AG 2FGGA 2PRTA 4LFCE 4J8ZA 2WDCA 2EOJA 5A6BA 4F2JC 4IYPC 4XPNA 4F6MA 1XZWA 5A6BD 3H67A 1NEIA 4DR7E 4DR1E 3P71C 2E1MA 4DV2E 1N34E 1UF3A 2VQFE 3OTOE 4BC7A 2EL6A 1ZR9A 1A1FA 4DUYE 1T4NA 2DXLA 2LE2A 2NYLC 4KBPA 2EMHA 4LF8E 1YYWA 4RH8A 2NYMC 4BHBA 4DHLA 3THNA 4KKZA 5T6JA 4LF9E 4DSYA 2YRKA 4X9JA 2EM0A 2JPAA 5C1VA 3DSDA 1OI8A 3L00A 2UXCE 2GHFA 4YHHE 2KKNA 3M99B 3IWCA 2ELZA 2EN6A 3VK6A 2CSHA 2K7IA 5A2QC 2EOMA 2V89A 2ZO9B 4DR5E 4RHBB 2EN3A 2V87A 3D03A 2EL5A 3F6GA 2YU5A 2M4IA 3THOB 2EP3A 4X62E 2YRMA 2UU9E 2MC5A 4HTGA 3IWBA 2M1SA 2EPXA 3VYYA 2EPPA 3BIDA 2EMWA 3MHHC 4B2OA 2DLQA 2JOBA 1TCOA 2YTPA 4OX9E 1X48A 2RS7A 5AC4A 2EMLA 2EN7A 4B3ME 2R1FA 2Z06A 2EL4A 4R2DA 2NABA 3TQMA 2DGCA 4JV5E 1FJMA 4BBYA 3EGGA 3ECRA 2EJ4A 4DV4E 2LTSA 3C5WC 4LU9A 2CT1A 4P7DA 4LF4E 4YKEA 2DIXA 5IOHA 2RPCA 2ENHA 2EMXA 4ZYGA 2YTQA 1DGCA 2M9AA 1WHNA 2YT4A 4H1YP 4DR6E 4N4RB 3VYXA 2VQEE 2EQ1A 1JK1A 1N36E 1RC7A 2MC6A 1A1KA 2N3HA 4DMIA 1RMDA 2EM8A 2UUCE 5IT9C 2NA2A 5IXMB 4JI4E 3ADIA 2YTIA 5LLQA 1UILA 4F9AB 1WXRA 4R2QA 1OIDA 2YVTA 3FGAC 4IL1A 3J7Yp 4LF5E 4GKKE 5JPFA 1J5EE 3H09A 3JU0A 5A6AA 1T4OA 2DB2A 3BBGA 4IS1C 2Z1AA 3J80C 1GQEA 1AH5A 1MEYC 1NCSA 3IVEA 2YTDA 4JI7E 3T1HE 4ZYDA 1F2IG 2YTEA 1YSAC 1KYQA 1SR9A 2IHR1 2JR1A 2LJUA 2BCDA 2IE4C 2IE3C 1KJKA 2F4VE 3VHTB 4X65E 3IWDA 3V4YA 4H2FA 1SFEA 2WDFA 2G7HA 2WZOA 1X5WA 2O8GA 4M0VA 3PSNA 3QG5C 4I5LC 4LFBE 2Z72A 1Z1BA 3HQ1A 2USHA 5ADZA 3GVEA 3ICFA 4MP0A 3HXLA 1PJQA 3UK3C 2EOXA 1JK2A 2NXFA 4DKKA 2LRSA 3KZZA 1HO5A 2EMBA 1U32A 4FCXA 2GLIA 3DJWA 1S3LA 1XNQE 1HP1A 1T71A 1QNTA 4ZVZA 2O8AA 3RMPA 5KL4A 4LFAE 1IBME 4I5NC 3H66A 2BQ8X 2EM4A 4JA7A 2CTDA 3OMLA 1FKAE 4JI5E 2DMIA 1IMUA 2EN4A 2EMKA 4WSPA 5KL3A 1HR0E 1TF3A 1S95A 1QFCA 3H64A
chains in the Genus database with same CATH topology
4G9JA 3ZU0A 4B2OA 1TCOA 1KBPA 3H60A 1MF8A 3EGHA 3H63A 4WWLA 2Z06A 4V0WA 3AV0A 2QFRA 3QFKA 4FBWA 4F0ZA 1FJMA 3E7BA 3RQZA 4O43A 3EGGA 3H61A 2A22A 5B8IA 1UTEA 1NNWA 3C5WC 2Q8UA 4LU9A 1WAO1 4YKEA 5IOHA 3K7WC 1XM7A 3IB8A 4NZVA 3IVDA 4MOVA 4ORCA 4HD0A 3KBPA 4LTYA 1USHA 4O4KA 1S3NA 2XMOA 4ZX2A 4H2IA 2BDXA 3E0JA 4OR9A 4H1YP 2GJUA 4H2GA 5GTUA 4H1SA 3T1IA 4J6OA 3RL4A 2CV9A 4UT3A 3IB7A 1IT6A 3K7VC 2JOGA 4UT3B 4V0XA 1G5BA 2P6BA 1T70A 3HVQA 2ZOAA 2YVTA 1OIDA 1Z2WA 3H62B 3FGAC 3DW8C 5INBA 4IL1A 5HPEA 5JJTA 2AHDA 5JPFA 2R17A 4JA9A 4UT2A 3RL5A 5EQVA 2Z1AA 1QHWA 4O24A 2WDDA 4V0VA 1Z2XA 3IVEA 4UWQA 1SU1A 3LL8A 2WDCA 4IYPC 4XPNA 1XZWA 3H67A 4FBKA 2BCDA 2IE4C 3TGHA 2IE3C 1V73A 3P71C 2HYOA 4TUGA 4TUIA 3H68A 3AUZA 1JK7A 3V4YA 4H2FA 1UF3A 2HY1A 3E7AA 4ORAA 4MOYA 4O5GA 2WDFA 3QFOA 2O8GA 2WDEA 3C9FA 4M0VA 2YEQA 3QG5C 1II7A 3PSNA 3QFMA 4I5LC 4LACC 2DXLA 2Z72A 4Q7FA 2NYLC 4KBPA 3CK2A 4H2BA 2USHA 3GVEA 2ZBMA 2NYMC 3ICFA 4MP0A 1S70A 3THNA 2NPPC 4DHLA 4KKZA 4DSYA 2NXFA 2DFJA 1M63A 3DSDA 5C1VA 1AUIA 1HO5A 1OI8A 1U32A 4FCXA 2KKNA 3PSOA 5DNYA 1S3LA 3FLOA 1HP1A 1T71A 5F3WA 4ZVZA 2O8AA 4I5NC 1HPUA 1W24A 2ZO9B 3JYFA 4FBQA 5J28A 3H66A 2BQ8X 1WARA 3QFNA 2QFPA 1S8EA 3D03A 3H69A 4JA7A 4ORBA 4DT2A 3THOB 3DSCA 1S3MA 2IAEC 3RL3A 5JPEA 1OIEA 3ZTVA 1S95A 2DXNA 3N5UA 1QFCA 2QJCA 2HYPA 3H64A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G9J A;  3ZU0 A;  4B2O A;  1TCO A;  1KBP A;  3H60 A;  1MF8 A;  3EGH A;  3H63 A;  4WWL A;  2Z06 A;  4V0W A;  3AV0 A;  2QFR A;  3QFK A;  4FBW A;  4F0Z A;  1FJM A;  3E7B A;  3RQZ A;  4O43 A;  3EGG A;  3H61 A;  2A22 A;  5B8I A;  1UTE A;  1NNW A;  3C5W C;  2Q8U A;  4LU9 A;  1WAO 1;  4YKE A;  5IOH A;  3K7W C;  1XM7 A;  3IB8 A;  4NZV A;  3IVD A;  4MOV A;  4ORC A;  4HD0 A;  3KBP A;  4LTY A;  1USH A;  4O4K A;  1S3N A;  2XMO A;  4ZX2 A;  4H2I A;  2BDX A;  4OR9 A;  4H1Y P;  2GJU A;  4H2G A;  5GTU A;  4H1S A;  3T1I A;  4J6O A;  3RL4 A;  2CV9 A;  4UT3 A;  3IB7 A;  1IT6 A;  3K7V C;  2JOG A;  4UT3 B;  4V0X A;  1G5B A;  2P6B A;  1T70 A;  3HVQ A;  2YVT A;  1OID A;  1Z2W A;  3H62 B;  3FGA C;  3DW8 C;  5INB A;  4IL1 A;  5HPE A;  5JJT A;  2AHD A;  5JPF A;  2R17 A;  4JA9 A;  4UT2 A;  3RL5 A;  5EQV A;  2Z1A A;  1QHW A;  4O24 A;  2WDD A;  4V0V A;  1Z2X A;  3IVE A;  4UWQ A;  1SU1 A;  3LL8 A;  2WDC A;  4IYP C;  4XPN A;  1XZW A;  3H67 A;  4FBK A;  2BCD A;  2IE4 C;  3TGH A;  2IE3 C;  1V73 A;  3P71 C;  2HYO A;  4TUG A;  4TUI A;  3H68 A;  3AUZ A;  1JK7 A;  3V4Y A;  4H2F A;  1UF3 A;  2HY1 A;  3E7A A;  4ORA A;  4MOY A;  4O5G A;  2WDF A;  3QFO A;  2O8G A;  2WDE A;  3C9F A;  4M0V A;  3PSN A;  3QG5 C;  1II7 A;  3QFM A;  4I5L C;  4LAC C;  2Z72 A;  4Q7F A;  2NYL C;  4KBP A;  3CK2 A;  4H2B A;  2USH A;  3GVE A;  2ZBM A;  2NYM C;  3ICF A;  4MP0 A;  1S70 A;  3THN A;  2NPP C;  4DHL A;  4KKZ A;  4DSY A;  2NXF A;  2DFJ A;  1M63 A;  5C1V A;  3DSD A;  1HO5 A;  1AUI A;  1OI8 A;  1U32 A;  4FCX A;  2KKN A;  3PSO A;  5DNY A;  1S3L A;  1HP1 A;  1T71 A;  5F3W A;  4ZVZ A;  2O8A A;  4I5N C;  1HPU A;  1W24 A;  3JYF A;  4FBQ A;  5J28 A;  3H66 A;  2BQ8 X;  1WAR A;  3QFN A;  2QFP A;  1S8E A;  3H69 A;  4JA7 A;  4ORB A;  4DT2 A;  3THO B;  3DSC A;  1S3M A;  2IAE C;  3RL3 A;  5JPE A;  1OIE A;  3ZTV A;  1S95 A;  3N5U A;  1QFC A;  2QJC A;  2HYP A;  3H64 A; 
#chains in the Genus database with same CATH topology
 1MGT A;  4DR4 E;  2EPO A;  2LJH A;  1XNR E;  5CFF E;  4M30 A;  4B3S E;  1MF8 A;  3EGH A;  3H63 A;  2K4V A;  2YTG A;  4WWL A;  4F9B B;  2WBT A;  5A69 A;  1X6F A;  2EOQ A;  2YU8 A;  2UXD E;  4FBW A;  1GZ6 A;  3C4B A;  3RQZ A;  5LMU E;  3H61 A;  2A22 A;  1BB8 A;  1NNW A;  2EQ0 A;  4L8N A;  1AAY A;  1ZU1 A;  4I8O A;  1A1I A;  2HGH A;  2LUP B;  4ORC A;  1LLM C;  2EMF A;  3K6Q A;  2I9I A;  4O4K A;  1S3N A;  3HPS A;  2KOU A;  2DMY A;  3EPL A;  2L2M A;  2RQL A;  4JI3 E;  4M2Z A;  4DV3 E;  4WYQ B;  5KL2 A;  4H2G A;  2EOR A;  2WBU A;  5AE2 A;  4H1S A;  4UT3 A;  2EE8 A;  2VE7 C;  2ADR A;  2YRH A;  2J7J A;  1DQ3 A;  4DV5 E;  1IT6 A;  3IB7 A;  5LMN E;  3K7V C;  2JOG A;  4UT3 B;  4V0X A;  2KON A;  2B3T B;  1EH6 A;  2DLK A;  2EOH A;  2EM3 A;  1L4S A;  2RTX A;  1YFH A;  3HVQ A;  2EMI A;  3LML A;  4X8W A;  1A1G A;  2ZOA A;  3H62 B;  2LT7 A;  4WXD A;  2LMZ A;  2HC5 A;  3DW8 C;  1WJP A;  4JA9 A;  4UT2 A;  3RL5 A;  4BCA A;  2NUG A;  1QHW A;  1TN9 A;  4GKJ E;  4V0V A;  2BB8 A;  4BMJ A;  4R8O A;  2YTF A;  4JI0 E;  4UWQ A;  2ENC A;  4JI8 E;  1HNW E;  2VRD A;  1STU A;  2B7V A;  1X49 A;  2EM9 A;  4NXM E;  1ZBQ A;  2HHH E;  5FLX C;  4TUG A;  3TGH A;  2HYO A;  2EPA A;  4P78 A;  3FIG A;  2RSM A;  1XMO E;  3E7A A;  4MOY A;  4O5G A;  1N33 E;  3QFO A;  2WDE A;  2ENA A;  3J81 C;  1EH8 A;  4DR2 E;  2EPN A;  2RS6 A;  1EH7 A;  3CK2 A;  2YTN A;  1BBO A;  2MKN A;  2YSP A;  2E5L E;  4B3R E;  1IQO A;  1UHZ A;  2DFJ A;  2V83 A;  1M63 A;  2L33 A;  3MSW A;  1IQS A;  4WSG A;  5DNY A;  5KL7 A;  2L3J A;  2ZM6 E;  5F3W A;  3BGH A;  2JY9 A;  1X3C A;  2H36 X;  2R76 A;  2B7T A;  2LBS B;  1W24 A;  3JYF A;  4DV1 E;  4WXC A;  5J28 A;  1WAR A;  3QFN A;  4HEI A;  1S8E A;  2QFP A;  4DV7 E;  4ORB A;  2YPN A;  4LF6 E;  1HNX E;  4DT2 A;  3DSC A;  4YY3 E;  1S3M A;  3RL3 A;  5AE3 A;  1OIE A;  4OOG C;  2FTX B;  4WPY A;  1X6E A;  5A6J A;  2HYP A;  2EPU A;  4MLQ A;  4LAC C;  1PDA A;  4LF7 E;  2EMG A;  4G9J A;  3ZU0 A;  4F9C B;  4NXN E;  3H60 A;  2LVH A;  2N3G A;  2MDR A;  2EPZ A;  4DV6 E;  4V0W A;  2QFR A;  2I13 A;  4R2C A;  2YTO A;  4O43 A;  4NHR A;  5LL6 R;  4R2P A;  1UTE A;  2EOI A;  3P1X A;  2JVA A;  2B9D A;  2F8B A;  2VF1 A;  1WAO 1;  2V8Q B;  2L3C A;  2LV2 A;  3ADG A;  1XM7 A;  3IB8 A;  3C6K A;  1A1H A;  4HD0 A;  4LTY A;  1A1L A;  4IJD A;  4KZS A;  2BDX A;  3E0J A;  4OR9 A;  3JAM C;  5IV8 B;  2V85 A;  2WCC 3;  2EOY A;  4R2S A;  3T1I A;  1PKP A;  4J6O A;  1J26 A;  2CV9 A;  1RQ0 A;  3C4T A;  4BC9 A;  1TF6 A;  1DI2 A;  5KL6 A;  4KHP E;  1G5B A;  3MHS C;  4B3T E;  4WX9 A;  1T70 A;  1HNZ E;  4JI1 E;  1Z2W A;  1YPN A;  2WBS A;  5INB A;  2EPL X;  2JP9 A;  2EMY A;  5JJT A;  1N3G A;  2NUE A;  2E72 A;  1T4L B;  2WDD A;  5AE1 A;  2V88 A;  2JYA A;  1Z2X A;  2EPC A;  4R03 A;  1SU1 A;  3LL8 A;  3LLH A;  2EPM X;  1N32 E;  2V86 A;  2LO3 A;  4FBK A;  2ODR D;  1V73 A;  4TUI A;  3H68 A;  1I94 E;  3T1Y E;  2EOF A;  2DRP A;  3AUZ A;  1JK7 A;  1EKZ A;  2HY1 A;  4ORA A;  2EPK X;  3C9F A;  4F6N A;  2EMC A;  2L6M A;  1II7 A;  2YEQ A;  3QFM A;  2EN1 A;  2YSO A;  2RSI A;  4GEQ B;  3ADL A;  2EWL A;  3KZY A;  4R2R A;  3EPH A;  4K0K E;  4Q7F A;  1T39 A;  2GPI A;  1PJT A;  4H2B A;  2ODR C;  1A1J A;  2ZBM A;  2HJJ A;  1S70 A;  2NPP C;  1YUJ A;  2L8T A;  1YYO A;  2LTR A;  4JYA E;  2UXB E;  4BS9 A;  1AUI A;  2YTJ A;  2UUB E;  4Q28 A;  3PSO A;  4MLV A;  2LCE A;  3FLO A;  4JI6 E;  1X6H A;  2JOX A;  1HPU A;  2EM2 A;  4ZYE A;  1G2F C;  3JTZ A;  4FBQ A;  1X47 A;  2EN2 A;  2EQ3 A;  2YZT A;  3BF2 A;  2EOZ A;  1YYK A;  3H69 A;  5KL5 A;  1ZBT A;  2IAE C;  5JPE A;  3ADJ A;  1B69 A;  3ZTV A;  3HPZ A;  1P47 A;  2EN8 A;  2CPN A;  1XMQ E;  2DXN A;  3N5U A;  2QJC A;  2D9H A;  2EOS A;  3EPK A;  4DUZ E;  3EQ1 A;  1WRJ A;  2L2N A;  1UN6 B;  2L92 A;  3DF6 A;  5BR8 E;  2M7Q A;  1KBP A;  2EOE A;  2DSY A;  3C6M A;  1YUI A;  2MDG A;  2EZ6 A;  1O0W A;  2KHX A;  4JI2 E;  3F6H A;  3AV0 A;  5AAS A;  3QFK A;  1BBG A;  2EMA A;  4F0Z A;  3E7B A;  2ELY A;  2NUF A;  1PJS A;  5B8I A;  4BHC A;  2FV4 B;  2EM7 A;  2EMZ A;  2Q8U A;  2EM6 A;  4R2A A;  2JWO A;  4FK5 C;  4R2E A;  1WHQ A;  3K7W C;  3ZOQ B;  4X66 E;  4KWY A;  4DV0 E;  2UUA E;  4GZN C;  4NZV A;  3IVD A;  4MOV A;  4Q35 B;  2MKD A;  5IWA E;  3KBP A;  4L5N C;  5AC5 A;  1USH A;  2XMO A;  1GTK A;  2EPR A;  3EPJ A;  4H2I A;  4ZX2 A;  4AQY E;  2BBG A;  4X64 E;  1UBD C;  2GJU A;  2LUQ A;  1T38 A;  3HTX A;  5GTU A;  2EOO A;  5A6K A;  2N8X A;  1FJG E;  3RL4 A;  4WFT A;  4F54 A;  2A25 A;  2JXP A;  1ZAA C;  4M9V C;  2YWQ A;  4DR3 E;  2P6B A;  4ZYH A;  1G2D C;  2L2K B;  1IBK E;  5TSE A;  5HPE A;  1IBL E;  2AHD A;  1YZ9 A;  2R17 A;  3KWR A;  5EQV A;  1QU6 A;  4O24 A;  2EM5 A;  3J7A G;  2FGG A;  2PRT A;  4LFC E;  4J8Z A;  2WDC A;  2EOJ A;  5A6B A;  4F2J C;  4IYP C;  4XPN A;  4F6M A;  1XZW A;  5A6B D;  3H67 A;  1NEI A;  4DR7 E;  4DR1 E;  3P71 C;  2E1M A;  4DV2 E;  1N34 E;  1UF3 A;  2VQF E;  3OTO E;  4BC7 A;  2EL6 A;  1ZR9 A;  1A1F A;  4DUY E;  1T4N A;  2DXL A;  2LE2 A;  2NYL C;  4KBP A;  2EMH A;  4LF8 E;  1YYW A;  4RH8 A;  2NYM C;  4BHB A;  4DHL A;  3THN A;  4KKZ A;  5T6J A;  4LF9 E;  4DSY A;  2YRK A;  4X9J A;  2EM0 A;  2JPA A;  5C1V A;  3DSD A;  1OI8 A;  3L00 A;  2UXC E;  2GHF A;  4YHH E;  2KKN A;  3M99 B;  3IWC A;  2ELZ A;  2EN6 A;  3VK6 A;  2CSH A;  2K7I A;  5A2Q C;  2EOM A;  2V89 A;  2ZO9 B;  4DR5 E;  4RHB B;  2EN3 A;  2V87 A;  3D03 A;  2EL5 A;  3F6G A;  2YU5 A;  2M4I A;  3THO B;  2EP3 A;  4X62 E;  2YRM A;  2UU9 E;  2MC5 A;  4HTG A;  3IWB A;  2M1S A;  2EPX A;  3VYY A;  2EPP A;  3BID A;  2EMW A;  3MHH C;  4B2O A;  2DLQ A;  2JOB A;  1TCO A;  2YTP A;  4OX9 E;  1X48 A;  2RS7 A;  5AC4 A;  2EML A;  2EN7 A;  4B3M E;  2R1F A;  2Z06 A;  2EL4 A;  4R2D A;  2NAB A;  3TQM A;  2DGC A;  4JV5 E;  1FJM A;  4BBY A;  3EGG A;  3ECR A;  2EJ4 A;  4DV4 E;  2LTS A;  3C5W C;  4LU9 A;  2CT1 A;  4P7D A;  4LF4 E;  4YKE A;  2DIX A;  5IOH A;  2RPC A;  2ENH A;  2EMX A;  4ZYG A;  2YTQ A;  1DGC A;  2M9A A;  1WHN A;  2YT4 A;  4H1Y P;  4DR6 E;  4N4R B;  3VYX A;  2VQE E;  2EQ1 A;  1JK1 A;  1N36 E;  1RC7 A;  2MC6 A;  1A1K A;  2N3H A;  4DMI A;  1RMD A;  2EM8 A;  2UUC E;  5IT9 C;  2NA2 A;  5IXM B;  4JI4 E;  3ADI A;  2YTI A;  5LLQ A;  1UIL A;  4F9A B;  1WXR A;  4R2Q A;  1OID A;  2YVT A;  3FGA C;  4IL1 A;  3J7Y p;  4LF5 E;  4GKK E;  5JPF A;  1J5E E;  3H09 A;  3JU0 A;  5A6A A;  1T4O A;  2DB2 A;  3BBG A;  4IS1 C;  2Z1A A;  3J80 C;  1GQE A;  1AH5 A;  1MEY C;  1NCS A;  3IVE A;  2YTD A;  4JI7 E;  3T1H E;  4ZYD A;  1F2I G;  2YTE A;  1YSA C;  1KYQ A;  1SR9 A;  2IHR 1;  2JR1 A;  2LJU A;  2BCD A;  2IE4 C;  2IE3 C;  1KJK A;  2F4V E;  3VHT B;  4X65 E;  3IWD A;  3V4Y A;  4H2F A;  1SFE A;  2WDF A;  2G7H A;  2WZO A;  1X5W A;  2O8G A;  4M0V A;  3PSN A;  3QG5 C;  4I5L C;  4LFB E;  2Z72 A;  1Z1B A;  3HQ1 A;  2USH A;  5ADZ A;  3GVE A;  3ICF A;  4MP0 A;  3HXL A;  1PJQ A;  3UK3 C;  2EOX A;  1JK2 A;  2NXF A;  4DKK A;  2LRS A;  3KZZ A;  1HO5 A;  2EMB A;  1U32 A;  4FCX A;  2GLI A;  3DJW A;  1S3L A;  1XNQ E;  1HP1 A;  1T71 A;  1QNT A;  4ZVZ A;  2O8A A;  3RMP A;  5KL4 A;  4LFA E;  1IBM E;  4I5N C;  3H66 A;  2BQ8 X;  2EM4 A;  4JA7 A;  2CTD A;  3OML A;  1FKA E;  4JI5 E;  2DMI A;  1IMU A;  2EN4 A;  2EMK A;  4WSP A;  5KL3 A;  1HR0 E;  1TF3 A;  1S95 A;  1QFC A;  3H64 A; 
#chains in the Genus database with same CATH homology
 4G9J A;  3ZU0 A;  4B2O A;  1TCO A;  1KBP A;  3H60 A;  1MF8 A;  3EGH A;  3H63 A;  4WWL A;  2Z06 A;  4V0W A;  3AV0 A;  2QFR A;  3QFK A;  4FBW A;  4F0Z A;  1FJM A;  3E7B A;  3RQZ A;  4O43 A;  3EGG A;  3H61 A;  2A22 A;  5B8I A;  1UTE A;  1NNW A;  3C5W C;  2Q8U A;  4LU9 A;  1WAO 1;  4YKE A;  5IOH A;  3K7W C;  1XM7 A;  3IB8 A;  4NZV A;  3IVD A;  4MOV A;  4ORC A;  4HD0 A;  3KBP A;  4LTY A;  1USH A;  4O4K A;  1S3N A;  2XMO A;  4ZX2 A;  4H2I A;  2BDX A;  3E0J A;  4OR9 A;  4H1Y P;  2GJU A;  4H2G A;  5GTU A;  4H1S A;  3T1I A;  4J6O A;  3RL4 A;  2CV9 A;  4UT3 A;  3IB7 A;  1IT6 A;  3K7V C;  2JOG A;  4UT3 B;  4V0X A;  1G5B A;  2P6B A;  1T70 A;  3HVQ A;  2ZOA A;  2YVT A;  1OID A;  1Z2W A;  3H62 B;  3FGA C;  3DW8 C;  5INB A;  4IL1 A;  5HPE A;  5JJT A;  2AHD A;  5JPF A;  2R17 A;  4JA9 A;  4UT2 A;  3RL5 A;  5EQV A;  2Z1A A;  1QHW A;  4O24 A;  2WDD A;  4V0V A;  1Z2X A;  3IVE A;  4UWQ A;  1SU1 A;  3LL8 A;  2WDC A;  4IYP C;  4XPN A;  1XZW A;  3H67 A;  4FBK A;  2BCD A;  2IE4 C;  3TGH A;  2IE3 C;  1V73 A;  3P71 C;  2HYO A;  4TUG A;  4TUI A;  3H68 A;  3AUZ A;  1JK7 A;  3V4Y A;  4H2F A;  1UF3 A;  2HY1 A;  3E7A A;  4ORA A;  4MOY A;  4O5G A;  2WDF A;  3QFO A;  2O8G A;  2WDE A;  3C9F A;  4M0V A;  2YEQ A;  3QG5 C;  1II7 A;  3PSN A;  3QFM A;  4I5L C;  4LAC C;  2DXL A;  2Z72 A;  4Q7F A;  2NYL C;  4KBP A;  3CK2 A;  4H2B A;  2USH A;  3GVE A;  2ZBM A;  2NYM C;  3ICF A;  4MP0 A;  1S70 A;  3THN A;  2NPP C;  4DHL A;  4KKZ A;  4DSY A;  2NXF A;  2DFJ A;  1M63 A;  3DSD A;  5C1V A;  1AUI A;  1HO5 A;  1OI8 A;  1U32 A;  4FCX A;  2KKN A;  3PSO A;  5DNY A;  1S3L A;  3FLO A;  1HP1 A;  1T71 A;  5F3W A;  4ZVZ A;  2O8A A;  4I5N C;  1HPU A;  1W24 A;  2ZO9 B;  3JYF A;  4FBQ A;  5J28 A;  3H66 A;  2BQ8 X;  1WAR A;  3QFN A;  2QFP A;  1S8E A;  3D03 A;  3H69 A;  4JA7 A;  4ORB A;  4DT2 A;  3THO B;  3DSC A;  1S3M A;  2IAE C;  3RL3 A;  5JPE A;  1OIE A;  3ZTV A;  1S95 A;  2DXN A;  3N5U A;  1QFC A;  2QJC A;  2HYP A;  3H64 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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