2Q8UA

Crystal structure of mre11 from thermotoga maritima msb8 (tm1635) at 2.20 a resolution
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
329
structure length
308
Chain Sequence
HHHHHVINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair.
pubmed doi rcsb
source organism Thermotoga maritima msb8
molecule tags Hydrolase
molecule keywords Exonuclease, putative
total genus 94
structure length 308
sequence length 329
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.160.210 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain DNA double-strand break repair nuclease 2q8uA02
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2q8uA01
3H62B 4UT3B 1IT6A 3K7VC 1HPUA 4O43A 1FJMA 4MOVA 1UTEA 1G5BA 2NPPC 2BCDA 2A22A 2QFRA 2QJCA 4YKEA 3V4YA 4KKZA 4V0XA 1SU1A 2AHDA 2XMOA 3CK2A 4FBWA 2Q8UA 3C5WC 1V73A 4JA7A 1QFCA 1Z2XA 3H64A 3PSOA 4H2GA 5DNYA 3H61A 1XM7A 4H2BA 1Z2WA 2BDXA 2NYLC 2YVTA 4G9JA 3IVDA 2R17A 4ZVZA 1XZWA 3FGAC 4FBKA 3DSDA 1HO5A 3THNA 3K7WC 3QFKA 3QFOA 2IE3C 2WDDA 1TCOA 1AUIA 5INBA 1QHWA 2NYMC 3TGHA 2IE4C 3N5UA 3IB7A 4H1YP 4UT3A 3DSCA 3JYFA 1S3NA 5F3WA 4ORCA 2BQ8X 2O8GA 2HYOA 4MP0A 4ORAA 4UT2A 4UWQA 4HD0A 4B2OA 1HP1A 1S8EA 1KBPA 2P6BA 2CV9A 3KBPA 1WAO1 4V0VA 2WDCA 4TUIA 4O24A 4O5GA 3H67A 4KBPA 4Q7FA 3RQZA 4IL1A 5J28A 3GVEA 3THOB 2WDEA 3ICFA 2ZBMA 4M0VA 2DFJA 1MF8A 4JA9A 4O4KA 1II7A 4J6OA 1M63A 1NNWA 4H2FA 3EGGA 2Z06A 1USHA 4LU9A 3EGHA 2Z1AA 2Z72A 4XPNA 4IYPC 4DHLA 3QFNA 4ZX2A 1W24A 5GTUA 5JJTA 3H68A 5HPEA 2GJUA 4V0WA 1S70A 1OI8A 4ORBA 1T71A 3ZTVA 2O8AA 3P71C 4I5LC 4LTYA 3RL4A 5IOHA 3E7AA 5JPEA 3IVEA 3H63A 3AUZA 5C1VA 2NXFA 3HVQA 3T1IA 3RL5A 3ZU0A 1OIDA 3PSNA 3H60A 2WDFA 3AV0A 5EQVA 2JOGA 3E7BA 4I5NC 4MOYA 4LACC 5JPFA 3QG5C 3RL3A 4DSYA 2HYPA 1WARA 2IAEC 4FCXA 3C9FA 2KKNA 3QFMA 2HY1A 2USHA 3LL8A 4NZVA 1T70A 2QFPA 4FBQA 3DW8C 1OIEA 1JK7A 4F0ZA 1S95A 1S3LA 4H2IA 4WWLA 1S3MA 4H1SA 1UF3A 4TUGA 1U32A 4OR9A 3IB8A 3H66A 3H69A 5B8IA 4DT2A
chains in the Genus database with same CATH superfamily
1BBOA 2CT1A 5A6BD 1HPUA 1XMQE 4O43A 4JI6E 2EM0A 4WFTA 4KKZA 2I13A 1QNTA 1A1IA 1SU1A 3CK2A 2EOYA 1UILA 2VQFE 1FJGE 1V73A 4LFCE 4WYQB 3H64A 4H2GA 2EPKX 3HQ1A 5KL4A 4NXME 3H09A 1XM7A 4JV5E 1EH8A 2LVHA 3LMLA 3ADJA 3BBGA 1HNWE 2ZM6E 1IQSA 1YSAC 3IVDA 2R17A 1TN9A 2EM5A 4BS9A 2EPZA 2DXNA 1HO5A 3F6GA 2ZO9B 2EM4A 3KWRA 2YU8A 4WSPA 2RS6A 1QHWA 2IHR1 1IMUA 4H1YP 3K6QA 2YTDA 5F3WA 2BQ8X 4BMJA 2EOOA 2V86A 2EPPA 2EM3A 2EPUA 4DUYE 3C4BA 3OMLA 2UUBE 3VK6A 4UWQA 2YTOA 1EKZA 2R76A 2YSPA 4B3TE 1IQOA 2NA2A 2EN3A 2EP3A 3C6MA 4M2ZA 4Q7FA 2YU5A 4IL1A 3J80C 4J8ZA 3GVEA 3THOB 2WBSA 4KHPE 2L92A 4DR6E 2E72A 2EPLX 4R2SA 2ZBMA 2DFJA 1MF8A 4DR3E 4JI7E 1WRJA 5AASA 5IXMB 2M9AA 1DGCA 2RSMA 3EGHA 2DGCA 2K7IA 2Z72A 3VYYA 1ZR9A 1DQ3A 2EL5A 5GTUA 2EOQA 4GKJE 2EE8A 1S70A 2YEQA 1X49A 2EN6A 2JR1A 2DMIA 2O8AA 3RL4A 1PJSA 2YTEA 3IVEA 4MLQA 2RQLA 3RMPA 3F6HA 2NABA 3BIDA 5KL3A 2UU9E 4X66E 2YTNA 3EPJA 1HNXE 4HEIA 5LL6R 2USHA 3QFMA 2B3TB 4LFAE 2B7VA 4GKKE 2EOIA 1X48A 4HTGA 4RH8A 5AC5A 2V89A 1OIEA 1S95A 2DXLA 2ENHA 3EPHA 2RTXA 2EMZA 1U32A 4OR9A 2EWLA 3H66A 2LT7A 4DKKA 2EOSA 2EM6A 1RC7A 2EMWA 4UT3B 1IT6A 4MOVA 2LUPB 1UTEA 2V83A 2BCDA 2I9IA 2QJCA 4WX9A 4YKEA 3V4YA 3J7AG 4BC9A 3MHSC 4JI5E 2EMLA 4MLVA 1HR0E 2AHDA 4ZYEA 4YHHE 2BB8A 2LUQA 3C5WC 4JA7A 5CFFE 3DF6A 1QFCA 1Z2XA 3PSOA 5DNYA 1XMOE 4R8OA 3H61A 1T39A 1KJKA 1EH6A 2L8TA 4B3SE 2YVTA 4GZNC 4F9CB 4NXNE 1GQEA 2EN1A 2EORA 3TQMA 2E1MA 3C6KA 1YFHA 2PRTA 2L3JA 3QFKA 2WDDA 1YYWA 2EOZA 1TCOA 5A2QC 3TGHA 2YRKA 1SR9A 4FK5C 3N5UA 2YWQA 4LFBE 2FGGA 1S3NA 2EOHA 2LO3A 5A6BA 2JWOA 2EN7A 2HYOA 4UT2A 4ORAA 1Z1BA 1X3CA 1I94E 2YTFA 3C4TA 4HD0A 1KBPA 2MKDA 3KBPA 1T4NA 4P78A 4I8OA 4OOGC 5KL6A 4L5NC 4R2DA 4TUIA 1UN6B 4V0VA 4O24A 1RMDA 4BHBA 5ADZA 5J28A 2MDRA 4F6MA 3IWDA 2WDEA 1J5EE 1ZAAC 2L6MA 1A1HA 1YZ9A 2EN4A 4J6OA 4NHRA 4X8WA 3KZYA 2Z06A 2EQ3A 2LTSA 3BF2A 1PDAA 2MDGA 4LF5E 3JTZA 1IBME 2EMKA 2CPNA 2EQ1A 2LRSA 4LU9A 4BBYA 4XPNA 4IYPC 2A25A 3T1HE 1PJTA 2ENAA 4ZYGA 4V0WA 4JI8E 2EL6A 1YPNA 1OI8A 1T71A 3ZTVA 5IOHA 2WCC3 3H63A 3AUZA 1ZU1A 4F2JC 4DR1E 2NXFA 3HVQA 4LF8E 3RL5A 3ZU0A 1X47A 3PSNA 1O0WA 1T4OA 2WDFA 2VE7C 1G2FC 2GPIA 4I5NC 2EJ4A 1YUIA 4N4RB 2HYPA 4FCXA 2EMFA 4DV3E 2JVAA 2EZ6A 3C9FA 1WXRA 1STUA 3LL8A 3LLHA 2B9DA 2EL4A 2EPXA 1GTKA 2DB2A 2UUCE 3J7Yp 4M9VC 4TUGA 3FIGA 1UF3A 3EPKA 4X65E 2LCEA 3D03A 4DT2A 3H62B 2YTQA 4JI4E 2UXCE 4DMIA 2L3CA 2KOUA 1IBLE 2DSYA 1G5BA 2NPPC 2M7QA 2A22A 4Q28A 2QFRA 3HXLA 2DIXA 2E5LE 5IT9C 1N36E 1A1GA 1YUJA 1T38A 1ZBTA 4R2EA 2XMOA 3T1YE 2N3HA 2EM2A 1X6HA 4F6NA 4BCAA 2NUGA 4X62E 1YYKA 2KONA 4RHBB 3M99B 2V88A 2FV4B 1BB8A 2M4IA 2N3GA 2RSIA 1X5WA 4AQYE 4H2BA 3EQ1A 2NYLC 2HC5A 4WSGA 2EMIA 2EPAA 2MC5A 2VF1A 4G9JA 2UUAE 2UXDE 5A6AA 4ZVZA 4FBKA 3DSDA 2WZOA 3THNA 1N34E 4IJDA 5IWAE 3VHTB 3K7WC 4DR2E 2IE3C 2DLQA 1F2IG 1AUIA 5INBA 2CTDA 2JP9A 2HJJA 3MSWA 3IB7A 3JYFA 4X64E 4ORCA 2EMXA 2VQEE 4LF6E 1IBKE 2ELYA 4B2OA 1HP1A 4LF7E 2NUEA 2P6BA 2CV9A 2EOFA 5LMNE 1WAO1 2EN8A 3MHHC 4O5GA 1P47A 5LMUE 2EMGA 1WHQA 2LBSB 4M0VA 2LE2A 3ZOQB 4DR7E 4JA9A 2JPAA 4M30A 2EPOA 4JI1E 1TF3A 5AE3A 2L33A 3EGGA 2DRPA 1NCSA 3ECRA 5BR8E 1N32E 2MKNA 1NEIA 2EM7A 4JI0E 3IWBA 2L2MA 1N3GA 5LLQA 2YRMA 4DV2E 2Z1AA 4F9BB 1J26A 2F4VE 4DHLA 4R2PA 2YZTA 1W24A 2HHHE 3H68A 2B7TA 2JYAA 2GJUA 2YTGA 4ORBA 2EOMA 2YTPA 2WBUA 5AE1A 3P71C 2JOXA 3E7AA 1UHZA 2JOBA 5JPEA 1AAYA 3EPLA 1LLMC 4P7DA 3T1IA 5KL2A 1OIDA 4X9JA 2RPCA 1BBGA 1RQ0A 3AV0A 5EQVA 5TSEA 3HTXA 2FTXB 4MOYA 4LACC 4JI3E 4R2CA 4DSYA 3L00A 2JXPA 4R2RA 2LJUA 2BBGA 2IAEC 1DI2A 2KKNA 1FKAE 2HY1A 2YSOA 4JYAE 4DV0E 5A69A 4NZVA 4DV7E 2ELZA 1ZBQA 1XNRE 1T70A 3FLOA 4FBQA 2GHFA 3UK3C 2K4VA 4B3ME 5KL7A 1PKPA 2EMAA 1QU6A 2ODRD 4KZSA 4Q35B 4WWLA 4OX9E 2LTRA 1XNQE 1S3MA 1PJQA 2N8XA 4DV6E 5B8IA 4ZYDA 2EPMX 2CSHA 3K7VC 4R03A 2LMZA 2EM8A 1FJMA 2NUFA 3JAMC 3BGHA 2V85A 4V0XA 2LJHA 3ADLA 2ADRA 4LF4E 4F9AB 4YY3E 4FBWA 2Q8UA 2EPRA 4K0KE 2EN2A 2R1FA 4DV4E 3VYXA 2EOEA 4WXDA 4DUZE 2EMBA 4GEQB 2EM9A 1N33E 3HPSA 5A6KA 2GLIA 1Z2WA 2ZOAA 2BDXA 1MEYC 1B69A 4KWYA 1XZWA 3FGAC 3J81C 4BC7A 4R2QA 2UXBE 3QFOA 4WPYA 3DJWA 2NYMC 2KHXA 5AE2A 2IE4C 4UT3A 3JU0A 3OTOE 1KYQA 3DSCA 2YTIA 2YTJA 2EMHA 2VRDA 2O8GA 4MP0A 1GZ6A 2ENCA 1L4SA 2V8QB 1S8EA 1X6FA 2RS7A 4B3RE 5IV8B 2L2KB 3ADIA 2WDCA 3H67A 4KBPA 2V87A 2EMYA 3RQZA 2G7HA 1UBDC 1A1FA 1A1LA 4JI2E 3ICFA 4DV1E 4O4KA 1EH7A 1WJPA 1MGTA 1II7A 1M63A 5KL5A 1NNWA 1JK1A 4H2FA 1AH5A 2EOJA 1USHA 2F8BA 2EOXA 2MC6A 1T4LB 3IWCA 4DR4E 1G2DC 2D9HA 2J7JA 1JK2A 3QFNA 4ZX2A 2EPNA 5JJTA 4F54A 5HPEA 4WXCA 2HGHA 4LTYA 4I5LC 2LV2A 1X6EA 4L8NA 4DR5E 1A1KA 4LF9E 1HNZE 5C1VA 1WHNA 2DMYA 4ZYHA 3KZZA 5FLXC 1A1JA 3H60A 2EMCA 2EQ0A 2JOGA 3E7BA 2YPNA 5T6JA 3E0JA 3QG5C 3P1XA 3RL3A 5JPFA 1WARA 3ADGA 2H36X 4BHCA 2DLKA 1TF6A 2QFPA 3HPZA 1SFEA 2M1SA 1YYOA 3DW8C 5AC4A 2JY9A 1JK7A 4F0ZA 4H2IA 1S3LA 5A6JA 2L2NA 2EPCA 2WBTA 4DV5E 4R2AA 4IS1C 2YT4A 4H1SA 2ODRC 3IB8A 3H69A 2YRHA
chains in the Genus database with same CATH topology
3H62B 4UT3B 1IT6A 3K7VC 1HPUA 4O43A 1FJMA 4MOVA 1UTEA 1G5BA 2NPPC 2BCDA 2A22A 2QFRA 2QJCA 4YKEA 3V4YA 4KKZA 4V0XA 1SU1A 2AHDA 2XMOA 3CK2A 4FBWA 2Q8UA 3C5WC 1V73A 4JA7A 1QFCA 1Z2XA 3H64A 3PSOA 4H2GA 5DNYA 3H61A 1XM7A 2ZOAA 4H2BA 1Z2WA 2BDXA 2NYLC 2YVTA 4G9JA 3IVDA 2R17A 4ZVZA 1XZWA 2DXNA 3FGAC 4FBKA 3DSDA 1HO5A 3THNA 2ZO9B 3K7WC 3QFKA 3QFOA 2IE3C 2WDDA 1TCOA 1AUIA 5INBA 1QHWA 2NYMC 3TGHA 2IE4C 3N5UA 3IB7A 4H1YP 4UT3A 3DSCA 3JYFA 1S3NA 5F3WA 4ORCA 2BQ8X 2O8GA 2HYOA 4MP0A 4ORAA 4UT2A 4UWQA 4HD0A 4B2OA 1HP1A 1S8EA 1KBPA 2P6BA 2CV9A 3KBPA 1WAO1 4V0VA 2WDCA 4TUIA 4O24A 4O5GA 3H67A 4KBPA 4Q7FA 3RQZA 4IL1A 5J28A 3GVEA 3THOB 2WDEA 3ICFA 2ZBMA 4M0VA 2DFJA 1MF8A 4JA9A 4O4KA 1II7A 4J6OA 1M63A 1NNWA 4H2FA 3EGGA 2Z06A 1USHA 4LU9A 3EGHA 2Z1AA 2Z72A 4XPNA 4IYPC 4DHLA 3QFNA 4ZX2A 1W24A 5GTUA 5JJTA 4DT2A 3H68A 5HPEA 2GJUA 4V0WA 1S70A 2YEQA 1OI8A 4ORBA 1T71A 3ZTVA 2O8AA 3P71C 4I5LC 4LTYA 3RL4A 5IOHA 3E7AA 5JPEA 3IVEA 3H63A 3AUZA 5C1VA 2NXFA 3HVQA 3T1IA 3RL5A 3ZU0A 1OIDA 3PSNA 3H60A 2WDFA 3AV0A 5EQVA 2JOGA 3E7BA 4I5NC 4MOYA 4LACC 3E0JA 3QG5C 3RL3A 4DSYA 2HYPA 1WARA 2IAEC 4FCXA 5JPFA 3C9FA 2KKNA 3QFMA 2HY1A 2USHA 3LL8A 4NZVA 1T70A 2QFPA 3FLOA 4FBQA 3DW8C 1OIEA 1JK7A 2DXLA 1S95A 1S3LA 4H2IA 4F0ZA 4WWLA 1S3MA 4H1SA 1UF3A 4TUGA 1U32A 4OR9A 3IB8A 3H66A 3H69A 5B8IA 3D03A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H62 B;  4UT3 B;  1IT6 A;  3K7V C;  1HPU A;  4O43 A;  1FJM A;  4MOV A;  1UTE A;  1G5B A;  2NPP C;  2BCD A;  2A22 A;  2QFR A;  2QJC A;  4YKE A;  3V4Y A;  4KKZ A;  4V0X A;  1SU1 A;  2AHD A;  2XMO A;  3CK2 A;  4FBW A;  2Q8U A;  3C5W C;  1V73 A;  4JA7 A;  1QFC A;  1Z2X A;  3H64 A;  3PSO A;  4H2G A;  5DNY A;  3H61 A;  1XM7 A;  4H2B A;  1Z2W A;  2BDX A;  2NYL C;  2YVT A;  4G9J A;  3IVD A;  2R17 A;  4ZVZ A;  1XZW A;  3FGA C;  4FBK A;  3DSD A;  1HO5 A;  3THN A;  3K7W C;  3QFK A;  3QFO A;  2IE3 C;  2WDD A;  1TCO A;  1AUI A;  5INB A;  1QHW A;  2NYM C;  3TGH A;  2IE4 C;  3N5U A;  3IB7 A;  4H1Y P;  4UT3 A;  3DSC A;  3JYF A;  1S3N A;  5F3W A;  4ORC A;  2BQ8 X;  2O8G A;  2HYO A;  4MP0 A;  4ORA A;  4UT2 A;  4UWQ A;  4HD0 A;  4B2O A;  1HP1 A;  1S8E A;  1KBP A;  2P6B A;  2CV9 A;  3KBP A;  1WAO 1;  4V0V A;  2WDC A;  4TUI A;  4O24 A;  4O5G A;  3H67 A;  4KBP A;  4Q7F A;  3RQZ A;  4IL1 A;  5J28 A;  3GVE A;  3THO B;  2WDE A;  3ICF A;  2ZBM A;  4M0V A;  2DFJ A;  1MF8 A;  4JA9 A;  4O4K A;  1II7 A;  4J6O A;  1M63 A;  1NNW A;  4H2F A;  3EGG A;  2Z06 A;  1USH A;  4LU9 A;  3EGH A;  2Z1A A;  2Z72 A;  4XPN A;  4IYP C;  4DHL A;  3QFN A;  4ZX2 A;  1W24 A;  5GTU A;  5JJT A;  3H68 A;  5HPE A;  2GJU A;  4V0W A;  1S70 A;  1OI8 A;  4ORB A;  1T71 A;  3ZTV A;  2O8A A;  3P71 C;  4I5L C;  4LTY A;  3RL4 A;  5IOH A;  3E7A A;  5JPE A;  3IVE A;  3H63 A;  3AUZ A;  5C1V A;  2NXF A;  3HVQ A;  3T1I A;  3RL5 A;  3ZU0 A;  1OID A;  3PSN A;  3H60 A;  2WDF A;  3AV0 A;  5EQV A;  2JOG A;  3E7B A;  4I5N C;  4MOY A;  4LAC C;  5JPF A;  3QG5 C;  3RL3 A;  4DSY A;  2HYP A;  1WAR A;  2IAE C;  4FCX A;  3C9F A;  2KKN A;  3QFM A;  2HY1 A;  2USH A;  3LL8 A;  4NZV A;  1T70 A;  2QFP A;  4FBQ A;  3DW8 C;  1OIE A;  1JK7 A;  4F0Z A;  1S95 A;  1S3L A;  4H2I A;  4WWL A;  1S3M A;  4H1S A;  1UF3 A;  4TUG A;  1U32 A;  4OR9 A;  3IB8 A;  3H66 A;  3H69 A;  5B8I A;  4DT2 A; 
#chains in the Genus database with same CATH topology
 1BBO A;  2CT1 A;  5A6B D;  1HPU A;  1XMQ E;  4O43 A;  4JI6 E;  2EM0 A;  4WFT A;  4KKZ A;  2I13 A;  1QNT A;  1A1I A;  1SU1 A;  3CK2 A;  2EOY A;  1UIL A;  2VQF E;  1FJG E;  1V73 A;  4LFC E;  4WYQ B;  3H64 A;  4H2G A;  2EPK X;  3HQ1 A;  5KL4 A;  4NXM E;  3H09 A;  1XM7 A;  4JV5 E;  1EH8 A;  2LVH A;  3LML A;  3ADJ A;  3BBG A;  1HNW E;  2ZM6 E;  1IQS A;  1YSA C;  3IVD A;  2R17 A;  1TN9 A;  2EM5 A;  4BS9 A;  2EPZ A;  2DXN A;  1HO5 A;  3F6G A;  2ZO9 B;  2EM4 A;  3KWR A;  2YU8 A;  4WSP A;  2RS6 A;  1QHW A;  2IHR 1;  1IMU A;  4H1Y P;  3K6Q A;  2YTD A;  5F3W A;  2BQ8 X;  4BMJ A;  2EOO A;  2V86 A;  2EPP A;  2EM3 A;  2EPU A;  4DUY E;  3C4B A;  3OML A;  2UUB E;  3VK6 A;  4UWQ A;  2YTO A;  1EKZ A;  2R76 A;  2YSP A;  4B3T E;  1IQO A;  2NA2 A;  2EN3 A;  2EP3 A;  3C6M A;  4M2Z A;  4Q7F A;  2YU5 A;  4IL1 A;  3J80 C;  4J8Z A;  3GVE A;  3THO B;  2WBS A;  4KHP E;  2L92 A;  4DR6 E;  2E72 A;  2EPL X;  4R2S A;  2ZBM A;  2DFJ A;  1MF8 A;  4DR3 E;  4JI7 E;  1WRJ A;  5AAS A;  5IXM B;  2M9A A;  1DGC A;  2RSM A;  3EGH A;  2DGC A;  2K7I A;  2Z72 A;  3VYY A;  1ZR9 A;  1DQ3 A;  2EL5 A;  5GTU A;  2EOQ A;  4GKJ E;  2EE8 A;  1S70 A;  2YEQ A;  1X49 A;  2EN6 A;  2JR1 A;  2DMI A;  2O8A A;  3RL4 A;  1PJS A;  2YTE A;  3IVE A;  4MLQ A;  2RQL A;  3RMP A;  3F6H A;  2NAB A;  3BID A;  5KL3 A;  2UU9 E;  4X66 E;  2YTN A;  3EPJ A;  1HNX E;  4HEI A;  5LL6 R;  2USH A;  3QFM A;  2B3T B;  4LFA E;  2B7V A;  4GKK E;  2EOI A;  1X48 A;  4HTG A;  4RH8 A;  5AC5 A;  2V89 A;  1OIE A;  1S95 A;  2DXL A;  2ENH A;  3EPH A;  2RTX A;  2EMZ A;  1U32 A;  4OR9 A;  2EWL A;  3H66 A;  2LT7 A;  4DKK A;  2EOS A;  2EM6 A;  1RC7 A;  2EMW A;  4UT3 B;  1IT6 A;  4MOV A;  2LUP B;  1UTE A;  2V83 A;  2BCD A;  2I9I A;  2QJC A;  4WX9 A;  4YKE A;  3V4Y A;  3J7A G;  4BC9 A;  3MHS C;  4JI5 E;  2EML A;  4MLV A;  1HR0 E;  2AHD A;  4ZYE A;  4YHH E;  2BB8 A;  2LUQ A;  3C5W C;  4JA7 A;  5CFF E;  3DF6 A;  1QFC A;  1Z2X A;  3PSO A;  5DNY A;  1XMO E;  4R8O A;  3H61 A;  1T39 A;  1KJK A;  1EH6 A;  2L8T A;  4B3S E;  2YVT A;  4GZN C;  4F9C B;  4NXN E;  1GQE A;  2EN1 A;  2EOR A;  3TQM A;  2E1M A;  3C6K A;  1YFH A;  2PRT A;  2L3J A;  3QFK A;  2WDD A;  1YYW A;  2EOZ A;  1TCO A;  5A2Q C;  3TGH A;  2YRK A;  1SR9 A;  4FK5 C;  3N5U A;  2YWQ A;  4LFB E;  2FGG A;  1S3N A;  2EOH A;  2LO3 A;  5A6B A;  2JWO A;  2EN7 A;  2HYO A;  4UT2 A;  4ORA A;  1Z1B A;  1X3C A;  1I94 E;  2YTF A;  3C4T A;  4HD0 A;  1KBP A;  2MKD A;  3KBP A;  1T4N A;  4P78 A;  4I8O A;  4OOG C;  5KL6 A;  4L5N C;  4R2D A;  4TUI A;  1UN6 B;  4V0V A;  4O24 A;  1RMD A;  4BHB A;  5ADZ A;  5J28 A;  2MDR A;  4F6M A;  3IWD A;  2WDE A;  1J5E E;  1ZAA C;  2L6M A;  1A1H A;  1YZ9 A;  2EN4 A;  4J6O A;  4NHR A;  4X8W A;  3KZY A;  2Z06 A;  2EQ3 A;  2LTS A;  3BF2 A;  1PDA A;  2MDG A;  4LF5 E;  3JTZ A;  1IBM E;  2EMK A;  2CPN A;  2EQ1 A;  2LRS A;  4LU9 A;  4BBY A;  4XPN A;  4IYP C;  2A25 A;  3T1H E;  1PJT A;  2ENA A;  4ZYG A;  4V0W A;  4JI8 E;  2EL6 A;  1YPN A;  1OI8 A;  1T71 A;  3ZTV A;  5IOH A;  2WCC 3;  3H63 A;  3AUZ A;  1ZU1 A;  4F2J C;  4DR1 E;  2NXF A;  3HVQ A;  4LF8 E;  3RL5 A;  3ZU0 A;  1X47 A;  3PSN A;  1O0W A;  1T4O A;  2WDF A;  2VE7 C;  1G2F C;  2GPI A;  4I5N C;  2EJ4 A;  1YUI A;  4N4R B;  2HYP A;  4FCX A;  2EMF A;  4DV3 E;  2JVA A;  2EZ6 A;  3C9F A;  1WXR A;  1STU A;  3LL8 A;  3LLH A;  2B9D A;  2EL4 A;  2EPX A;  1GTK A;  2DB2 A;  2UUC E;  3J7Y p;  4M9V C;  4TUG A;  3FIG A;  1UF3 A;  3EPK A;  4X65 E;  2LCE A;  3D03 A;  4DT2 A;  3H62 B;  2YTQ A;  4JI4 E;  2UXC E;  4DMI A;  2L3C A;  2KOU A;  1IBL E;  2DSY A;  1G5B A;  2NPP C;  2M7Q A;  2A22 A;  4Q28 A;  2QFR A;  3HXL A;  2DIX A;  2E5L E;  5IT9 C;  1N36 E;  1A1G A;  1YUJ A;  1T38 A;  1ZBT A;  4R2E A;  2XMO A;  3T1Y E;  2N3H A;  2EM2 A;  1X6H A;  4F6N A;  4BCA A;  2NUG A;  4X62 E;  1YYK A;  2KON A;  4RHB B;  3M99 B;  2V88 A;  2FV4 B;  1BB8 A;  2M4I A;  2N3G A;  2RSI A;  1X5W A;  4AQY E;  4H2B A;  3EQ1 A;  2NYL C;  2HC5 A;  4WSG A;  2EMI A;  2EPA A;  2MC5 A;  2VF1 A;  4G9J A;  2UUA E;  2UXD E;  5A6A A;  4ZVZ A;  4FBK A;  3DSD A;  2WZO A;  3THN A;  1N34 E;  4IJD A;  5IWA E;  3VHT B;  3K7W C;  4DR2 E;  2IE3 C;  2DLQ A;  1F2I G;  1AUI A;  5INB A;  2CTD A;  2JP9 A;  2HJJ A;  3MSW A;  3IB7 A;  3JYF A;  4X64 E;  4ORC A;  2EMX A;  2VQE E;  4LF6 E;  1IBK E;  2ELY A;  4B2O A;  1HP1 A;  4LF7 E;  2NUE A;  2P6B A;  2CV9 A;  2EOF A;  5LMN E;  1WAO 1;  2EN8 A;  3MHH C;  4O5G A;  1P47 A;  5LMU E;  2EMG A;  1WHQ A;  2LBS B;  4M0V A;  2LE2 A;  3ZOQ B;  4DR7 E;  4JA9 A;  2JPA A;  4M30 A;  2EPO A;  4JI1 E;  1TF3 A;  5AE3 A;  2L33 A;  3EGG A;  2DRP A;  1NCS A;  3ECR A;  5BR8 E;  1N32 E;  2MKN A;  1NEI A;  2EM7 A;  4JI0 E;  3IWB A;  2L2M A;  1N3G A;  5LLQ A;  2YRM A;  4DV2 E;  2Z1A A;  4F9B B;  1J26 A;  2F4V E;  4DHL A;  4R2P A;  2YZT A;  1W24 A;  2HHH E;  3H68 A;  2B7T A;  2JYA A;  2GJU A;  2YTG A;  4ORB A;  2EOM A;  2YTP A;  2WBU A;  5AE1 A;  3P71 C;  2JOX A;  3E7A A;  1UHZ A;  2JOB A;  5JPE A;  1AAY A;  3EPL A;  1LLM C;  4P7D A;  3T1I A;  5KL2 A;  1OID A;  4X9J A;  2RPC A;  1BBG A;  1RQ0 A;  3AV0 A;  5EQV A;  5TSE A;  3HTX A;  2FTX B;  4MOY A;  4LAC C;  4JI3 E;  4R2C A;  4DSY A;  3L00 A;  2JXP A;  4R2R A;  2LJU A;  2BBG A;  2IAE C;  1DI2 A;  2KKN A;  1FKA E;  2HY1 A;  2YSO A;  4JYA E;  4DV0 E;  5A69 A;  4NZV A;  4DV7 E;  2ELZ A;  1ZBQ A;  1XNR E;  1T70 A;  3FLO A;  4FBQ A;  2GHF A;  3UK3 C;  2K4V A;  4B3M E;  5KL7 A;  1PKP A;  2EMA A;  1QU6 A;  2ODR D;  4KZS A;  4Q35 B;  4WWL A;  4OX9 E;  2LTR A;  1XNQ E;  1S3M A;  1PJQ A;  2N8X A;  4DV6 E;  5B8I A;  4ZYD A;  2EPM X;  2CSH A;  3K7V C;  4R03 A;  2LMZ A;  2EM8 A;  1FJM A;  2NUF A;  3JAM C;  3BGH A;  2V85 A;  4V0X A;  2LJH A;  3ADL A;  2ADR A;  4LF4 E;  4F9A B;  4YY3 E;  4FBW A;  2Q8U A;  2EPR A;  4K0K E;  2EN2 A;  2R1F A;  4DV4 E;  3VYX A;  2EOE A;  4WXD A;  4DUZ E;  2EMB A;  4GEQ B;  2EM9 A;  1N33 E;  3HPS A;  5A6K A;  2GLI A;  1Z2W A;  2ZOA A;  2BDX A;  1MEY C;  1B69 A;  4KWY A;  1XZW A;  3FGA C;  3J81 C;  4BC7 A;  4R2Q A;  2UXB E;  3QFO A;  4WPY A;  3DJW A;  2NYM C;  2KHX A;  5AE2 A;  2IE4 C;  4UT3 A;  3JU0 A;  3OTO E;  1KYQ A;  3DSC A;  2YTI A;  2YTJ A;  2EMH A;  2VRD A;  2O8G A;  4MP0 A;  1GZ6 A;  2ENC A;  1L4S A;  2V8Q B;  1S8E A;  1X6F A;  2RS7 A;  4B3R E;  5IV8 B;  2L2K B;  3ADI A;  2WDC A;  3H67 A;  4KBP A;  2V87 A;  2EMY A;  3RQZ A;  2G7H A;  1UBD C;  1A1F A;  1A1L A;  4JI2 E;  3ICF A;  4DV1 E;  4O4K A;  1EH7 A;  1WJP A;  1MGT A;  1II7 A;  1M63 A;  5KL5 A;  1NNW A;  1JK1 A;  4H2F A;  1AH5 A;  2EOJ A;  1USH A;  2F8B A;  2EOX A;  2MC6 A;  1T4L B;  3IWC A;  4DR4 E;  1G2D C;  2D9H A;  2J7J A;  1JK2 A;  3QFN A;  4ZX2 A;  2EPN A;  5JJT A;  4F54 A;  5HPE A;  4WXC A;  2HGH A;  4LTY A;  4I5L C;  2LV2 A;  1X6E A;  4L8N A;  4DR5 E;  1A1K A;  4LF9 E;  1HNZ E;  5C1V A;  1WHN A;  2DMY A;  4ZYH A;  3KZZ A;  5FLX C;  1A1J A;  3H60 A;  2EMC A;  2EQ0 A;  2JOG A;  3E7B A;  2YPN A;  5T6J A;  3E0J A;  3QG5 C;  3P1X A;  3RL3 A;  5JPF A;  1WAR A;  3ADG A;  2H36 X;  4BHC A;  2DLK A;  1TF6 A;  2QFP A;  3HPZ A;  1SFE A;  2M1S A;  1YYO A;  3DW8 C;  5AC4 A;  2JY9 A;  1JK7 A;  4F0Z A;  4H2I A;  1S3L A;  5A6J A;  2L2N A;  2EPC A;  2WBT A;  4DV5 E;  4R2A A;  4IS1 C;  2YT4 A;  4H1S A;  2ODR C;  3IB8 A;  3H69 A;  2YRH A; 
#chains in the Genus database with same CATH homology
 3H62 B;  4UT3 B;  1IT6 A;  3K7V C;  1HPU A;  4O43 A;  1FJM A;  4MOV A;  1UTE A;  1G5B A;  2NPP C;  2BCD A;  2A22 A;  2QFR A;  2QJC A;  4YKE A;  3V4Y A;  4KKZ A;  4V0X A;  1SU1 A;  2AHD A;  2XMO A;  3CK2 A;  4FBW A;  2Q8U A;  3C5W C;  1V73 A;  4JA7 A;  1QFC A;  1Z2X A;  3H64 A;  3PSO A;  4H2G A;  5DNY A;  3H61 A;  1XM7 A;  2ZOA A;  4H2B A;  1Z2W A;  2BDX A;  2NYL C;  2YVT A;  4G9J A;  3IVD A;  2R17 A;  4ZVZ A;  1XZW A;  2DXN A;  3FGA C;  4FBK A;  3DSD A;  1HO5 A;  3THN A;  2ZO9 B;  3K7W C;  3QFK A;  3QFO A;  2IE3 C;  2WDD A;  1TCO A;  1AUI A;  5INB A;  1QHW A;  2NYM C;  3TGH A;  2IE4 C;  3N5U A;  3IB7 A;  4H1Y P;  4UT3 A;  3DSC A;  3JYF A;  1S3N A;  5F3W A;  4ORC A;  2BQ8 X;  2O8G A;  2HYO A;  4MP0 A;  4ORA A;  4UT2 A;  4UWQ A;  4HD0 A;  4B2O A;  1HP1 A;  1S8E A;  1KBP A;  2P6B A;  2CV9 A;  3KBP A;  1WAO 1;  4V0V A;  2WDC A;  4TUI A;  4O24 A;  4O5G A;  3H67 A;  4KBP A;  4Q7F A;  3RQZ A;  4IL1 A;  5J28 A;  3GVE A;  3THO B;  2WDE A;  3ICF A;  2ZBM A;  4M0V A;  2DFJ A;  1MF8 A;  4JA9 A;  4O4K A;  1II7 A;  4J6O A;  1M63 A;  1NNW A;  4H2F A;  3EGG A;  2Z06 A;  1USH A;  4LU9 A;  3EGH A;  2Z1A A;  2Z72 A;  4XPN A;  4IYP C;  4DHL A;  3QFN A;  4ZX2 A;  1W24 A;  5GTU A;  5JJT A;  4DT2 A;  3H68 A;  5HPE A;  2GJU A;  4V0W A;  1S70 A;  2YEQ A;  1OI8 A;  4ORB A;  1T71 A;  3ZTV A;  2O8A A;  3P71 C;  4I5L C;  4LTY A;  3RL4 A;  5IOH A;  3E7A A;  5JPE A;  3IVE A;  3H63 A;  3AUZ A;  5C1V A;  2NXF A;  3HVQ A;  3T1I A;  3RL5 A;  3ZU0 A;  1OID A;  3PSN A;  3H60 A;  2WDF A;  3AV0 A;  5EQV A;  2JOG A;  3E7B A;  4I5N C;  4MOY A;  4LAC C;  3E0J A;  3QG5 C;  3RL3 A;  4DSY A;  2HYP A;  1WAR A;  2IAE C;  4FCX A;  5JPF A;  3C9F A;  2KKN A;  3QFM A;  2HY1 A;  2USH A;  3LL8 A;  4NZV A;  1T70 A;  2QFP A;  3FLO A;  4FBQ A;  3DW8 C;  1OIE A;  1JK7 A;  2DXL A;  1S95 A;  1S3L A;  4H2I A;  4F0Z A;  4WWL A;  1S3M A;  4H1S A;  1UF3 A;  4TUG A;  1U32 A;  4OR9 A;  3IB8 A;  3H66 A;  3H69 A;  5B8I A;  3D03 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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