3ZTVA

Structure of haemophilus influenzae nad nucleotidase (nadn)
Total Genus 201
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
201
sequence length
566
structure length
565
Chain Sequence
HKAVELSILHINDHHSYLEPHETRINLNGQQTKVDIGGFSAVNAKLNKLRKKYKNPLVLHAGDAITGTLYFTLFGGSADAAVMNAGNFHYFTLGNHEFDAGNEGLLKLLEPLKIPVLSANVIPDKSSILYNKWKPYDIFTVDGEKIAIIGLDTVNKTVNSSSPGKDVKFYDEIATAQIMANALKQQGINKIILLSHAGSEKNIEIAQKVNDIDVIVTGDSHYLYGNDELRSLKLPVIYEYPLEFKNPNGEPVFVMEGWAYSAVVGDLGVKFSPEGIASITRKIPHVLMSSHKLQVKNSEGKWAELTGDERKKALDTLKSMKSISLDDHDAKTDKLIAKYKSEKDRLAQEIVGVITGSAMPGGSANRIPNKAGSNPEGSIATRFIAETMYNELKTVDLTIQNAGGVRADILPGNVTFNDAYTFLPFGNTLYTYKMEGSLVKQVLEDAMQFALVDGSTGAFPYGAGIRYEANETPNAEGKRLVSVEVLNKTQQWEPIDDNKRYLVGTNAYVAGGKDGYKTFGKLFNDPKYEGVDTYLPDAESFIKFMKKHPHFEAYTSSNVKFNAST
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The High-Resolution Crystal Structure of Periplasmic Haemophilus Influenzae Nad Nucleotidase Reveals a Novel Enzymatic Function of Human Cd73 Related to Nad Metabolism.
pubmed doi rcsb
source organism Haemophilus influenzae
molecule tags Hydrolase
molecule keywords NAD NUCLEOTIDASE
total genus 201
structure length 565
sequence length 566
ec nomenclature ec 3.1.3.5: 5'-nucleotidase.
pdb deposition date 2011-07-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF02872 5_nucleotid_C 5'-nucleotidase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3ztvA01
3.90.780.10 Alpha Beta Alpha-Beta Complex 5'-nucleotidase; domain 2 5'-Nucleotidase, C-terminal domain 3ztvA02
2XMOA 1NNWA 3PSOA 2JOGA 1II7A 4JA9A 1JK7A 5JPFA 4DHLA 1S95A 1G5BA 5C1VA 4UT2A 3H62B 1S3LA 2P6BA 4V0XA 1UF3A 2CV9A 3IVEA 3GVEA 3H67A 1OI8A 4TUGA 3RL4A 2NXFA 4MOYA 4O43A 1HO5A 3THOB 1HP1A 3FGAC 2GJUA 5JPEA 4ORBA 1S70A 3T1IA 3EGHA 3TGHA 2A22A 2KKNA 4YKEA 3THNA 2O8AA 3AV0A 2HYPA 1M63A 3DW8C 4IYPC 3E7AA 4ORCA 4KBPA 2WDFA 2YVTA 3H61A 3H64A 3H60A 1Z2WA 3K7WC 4J6OA 1U32A 2NYLC 2BCDA 3IB7A 1SU1A 4LACC 1UTEA 2Z72A 2Z1AA 3C9FA 1TCOA 2NPPC 4H2FA 3DSDA 4FBKA 4H1YP 2DFJA 4H2GA 4FBWA 4LTYA 4Q7FA 5EQVA 2R17A 3H66A 2USHA 3QG5C 4OR9A 1Z2XA 4H2BA 4V0WA 4DSYA 2IAEC 4IL1A 3P71C 1FJMA 5GTUA 4DT2A 1IT6A 4UT3B 4H1SA 2WDDA 3E7BA 4H2IA 4I5NC 5IOHA 1XZWA 3DSCA 3CK2A 1XM7A 3EGGA 1S8EA 5B8IA 3K7VC 5JJTA 4TUIA 4O24A 2AHDA 1S3MA 1WAO1 4ZX2A 3C5WC 1QFCA 3JYFA 5J28A 3H63A 2WDEA 2Z06A 3N5UA 3PSNA 3ZTVA 1AUIA 4NZVA 3RL3A 4HD0A 4G9JA 1T71A 2BDXA 2IE4C 3KBPA 4FCXA 4ZVZA 4XPNA 2NYMC 4UT3A 1S3NA 4KKZA 4LU9A 3LL8A 4I5LC 2O8GA 4FBQA 4WWLA 4V0VA 3IVDA 3H69A 3ICFA 2QJCA 5DNYA 4O5GA 4O4KA 3QFKA 5F3WA 4ORAA 4B2OA 3HVQA 3RL5A 1MF8A 2WDCA 4JA7A 2QFRA 3QFOA 2HY1A 1HPUA 1OIEA 3AUZA 4MOVA 4MP0A 3RQZA 5INBA 2HYOA 1OIDA 4UWQA 1WARA 1T70A 2BQ8X 3QFNA 3H68A 4M0VA 3ZU0A 1W24A 2QFPA 3QFMA 5HPEA 2ZBMA 1V73A 1QHWA 4F0ZA 1KBPA 2Q8UA 1USHA 3V4YA 2IE3C 3IB8A
chains in the Genus database with same CATH superfamily
2XMOA 1NNWA 3PSOA 2JOGA 1II7A 4JA9A 1JK7A 5JPFA 4DHLA 1S95A 1G5BA 5C1VA 4UT2A 3H62B 1S3LA 2P6BA 4V0XA 1UF3A 2CV9A 3IVEA 3GVEA 3H67A 1OI8A 4TUGA 3RL4A 2NXFA 4MOYA 4O43A 1HO5A 3THOB 1HP1A 3FGAC 2GJUA 5JPEA 4ORBA 1S70A 3T1IA 3EGHA 3TGHA 2A22A 2KKNA 4YKEA 3THNA 2O8AA 3AV0A 2HYPA 1M63A 3DW8C 4IYPC 3E7AA 4ORCA 4KBPA 2WDFA 2YVTA 3H61A 3H64A 3H60A 1Z2WA 3K7WC 4J6OA 1U32A 2NYLC 2BCDA 3IB7A 1SU1A 4LACC 1UTEA 2Z72A 2Z1AA 3C9FA 1TCOA 2NPPC 4H2FA 3DSDA 4FBKA 4H1YP 2DFJA 4H2GA 4FBWA 4LTYA 4Q7FA 5EQVA 2R17A 3H66A 2USHA 3QG5C 4OR9A 1Z2XA 4H2BA 4V0WA 4DSYA 2IAEC 4IL1A 3P71C 1FJMA 5GTUA 4DT2A 1IT6A 4UT3B 4H1SA 2WDDA 3E7BA 4H2IA 4I5NC 5IOHA 1XZWA 3DSCA 3CK2A 1XM7A 2ZOAA 3EGGA 1S8EA 5B8IA 3K7VC 5JJTA 2DXLA 4TUIA 4O24A 2AHDA 3E0JA 1S3MA 1WAO1 4ZX2A 3C5WC 1QFCA 3JYFA 5J28A 3H63A 2WDEA 2Z06A 3N5UA 3PSNA 3ZTVA 1AUIA 4NZVA 3RL3A 4HD0A 4G9JA 1T71A 2BDXA 2IE4C 3KBPA 4FCXA 4ZVZA 4XPNA 2NYMC 4UT3A 1S3NA 4KKZA 2YEQA 4LU9A 3LL8A 4I5LC 2O8GA 4FBQA 4WWLA 4V0VA 3IVDA 3H69A 3ICFA 2QJCA 5DNYA 4O5GA 4O4KA 3QFKA 5F3WA 4ORAA 4B2OA 3HVQA 3RL5A 1MF8A 2WDCA 3FLOA 4JA7A 3D03A 2QFRA 3QFOA 2ZO9B 2HY1A 1HPUA 1OIEA 3AUZA 4MOVA 4MP0A 3RQZA 5INBA 2HYOA 1OIDA 4UWQA 1WARA 2DXNA 1T70A 2BQ8X 3QFNA 3H68A 4M0VA 3ZU0A 1W24A 2QFPA 3QFMA 5HPEA 2ZBMA 1V73A 1QHWA 4F0ZA 1KBPA 2Q8UA 1USHA 3V4YA 2IE3C 3IB8A
chains in the Genus database with same CATH topology
2XMOA 1NNWA 3PSOA 2JOGA 1II7A 4JA9A 1JK7A 5JPFA 4DHLA 1S95A 1G5BA 5C1VA 4UT2A 3H62B 1S3LA 2P6BA 4V0XA 1UF3A 2CV9A 3IVEA 3GVEA 3H67A 1OI8A 4TUGA 3RL4A 2NXFA 4MOYA 4O43A 1HO5A 3THOB 1HP1A 3FGAC 2GJUA 5JPEA 4ORBA 1S70A 3T1IA 3EGHA 3TGHA 2A22A 2KKNA 4YKEA 3THNA 2O8AA 3AV0A 2HYPA 1M63A 3DW8C 4IYPC 3E7AA 4ORCA 4KBPA 2WDFA 2YVTA 3H61A 3H64A 3H60A 1Z2WA 3K7WC 4J6OA 1U32A 2NYLC 2BCDA 3IB7A 1SU1A 4LACC 1UTEA 2Z72A 2Z1AA 3C9FA 1TCOA 2NPPC 4H2FA 3DSDA 4FBKA 4H1YP 2DFJA 4H2GA 4FBWA 4LTYA 4Q7FA 5EQVA 2R17A 3H66A 2USHA 3QG5C 4OR9A 1Z2XA 4H2BA 4V0WA 4DSYA 2IAEC 4IL1A 3P71C 1FJMA 5GTUA 4DT2A 1IT6A 4UT3B 4H1SA 2WDDA 3E7BA 4H2IA 4I5NC 5IOHA 1XZWA 3DSCA 3CK2A 1XM7A 2ZOAA 3EGGA 1S8EA 5B8IA 3K7VC 5JJTA 2DXLA 4TUIA 4O24A 2AHDA 3E0JA 1S3MA 1WAO1 4ZX2A 3C5WC 1QFCA 3JYFA 5J28A 3H63A 2WDEA 2Z06A 3N5UA 3PSNA 3ZTVA 1AUIA 4NZVA 3RL3A 4HD0A 4G9JA 1T71A 2BDXA 2IE4C 3KBPA 4FCXA 4ZVZA 4XPNA 2NYMC 4UT3A 1S3NA 4KKZA 2YEQA 4LU9A 3LL8A 4I5LC 2O8GA 4FBQA 4WWLA 4V0VA 3IVDA 3H69A 3ICFA 2QJCA 5DNYA 4O5GA 4O4KA 3QFKA 5F3WA 4ORAA 4B2OA 3HVQA 3RL5A 1MF8A 2WDCA 3FLOA 4JA7A 3D03A 2QFRA 3QFOA 2ZO9B 2HY1A 1HPUA 1OIEA 3AUZA 4MOVA 4MP0A 3RQZA 5INBA 2HYOA 1OIDA 4UWQA 1WARA 2DXNA 1T70A 2BQ8X 3QFNA 3H68A 4M0VA 3ZU0A 1W24A 2QFPA 3QFMA 5HPEA 2ZBMA 1V73A 1QHWA 4F0ZA 1KBPA 2Q8UA 1USHA 3V4YA 2IE3C 3IB8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XMO A;  1NNW A;  3PSO A;  2JOG A;  1II7 A;  4JA9 A;  1JK7 A;  5JPF A;  4DHL A;  1S95 A;  1G5B A;  5C1V A;  4UT2 A;  3H62 B;  1S3L A;  2P6B A;  4V0X A;  1UF3 A;  2CV9 A;  3IVE A;  3GVE A;  3H67 A;  1OI8 A;  4TUG A;  3RL4 A;  2NXF A;  4MOY A;  4O43 A;  1HO5 A;  3THO B;  1HP1 A;  3FGA C;  2GJU A;  5JPE A;  4ORB A;  1S70 A;  3T1I A;  3EGH A;  3TGH A;  2A22 A;  2KKN A;  4YKE A;  3THN A;  2O8A A;  3AV0 A;  2HYP A;  1M63 A;  3DW8 C;  4IYP C;  3E7A A;  4ORC A;  4KBP A;  2WDF A;  2YVT A;  3H61 A;  3H64 A;  3H60 A;  1Z2W A;  3K7W C;  4J6O A;  1U32 A;  2NYL C;  2BCD A;  3IB7 A;  1SU1 A;  4LAC C;  1UTE A;  2Z72 A;  2Z1A A;  3C9F A;  1TCO A;  2NPP C;  4H2F A;  3DSD A;  4FBK A;  4H1Y P;  2DFJ A;  4H2G A;  4FBW A;  4LTY A;  4Q7F A;  5EQV A;  2R17 A;  3H66 A;  2USH A;  3QG5 C;  4OR9 A;  1Z2X A;  4H2B A;  4V0W A;  4DSY A;  2IAE C;  4IL1 A;  3P71 C;  1FJM A;  5GTU A;  4DT2 A;  1IT6 A;  4UT3 B;  4H1S A;  2WDD A;  3E7B A;  4H2I A;  4I5N C;  5IOH A;  1XZW A;  3DSC A;  3CK2 A;  1XM7 A;  3EGG A;  1S8E A;  5B8I A;  3K7V C;  5JJT A;  4TUI A;  4O24 A;  2AHD A;  1S3M A;  1WAO 1;  4ZX2 A;  3C5W C;  1QFC A;  3JYF A;  5J28 A;  3H63 A;  2WDE A;  2Z06 A;  3N5U A;  3PSN A;  3ZTV A;  1AUI A;  4NZV A;  3RL3 A;  4HD0 A;  4G9J A;  1T71 A;  2BDX A;  2IE4 C;  3KBP A;  4FCX A;  4ZVZ A;  4XPN A;  2NYM C;  4UT3 A;  1S3N A;  4KKZ A;  4LU9 A;  3LL8 A;  4I5L C;  2O8G A;  4FBQ A;  4WWL A;  4V0V A;  3IVD A;  3H69 A;  3ICF A;  2QJC A;  5DNY A;  4O5G A;  4O4K A;  3QFK A;  5F3W A;  4ORA A;  4B2O A;  3HVQ A;  3RL5 A;  1MF8 A;  2WDC A;  4JA7 A;  2QFR A;  3QFO A;  2HY1 A;  1HPU A;  1OIE A;  3AUZ A;  4MOV A;  4MP0 A;  3RQZ A;  5INB A;  2HYO A;  1OID A;  4UWQ A;  1WAR A;  1T70 A;  2BQ8 X;  3QFN A;  3H68 A;  4M0V A;  3ZU0 A;  1W24 A;  2QFP A;  3QFM A;  5HPE A;  2ZBM A;  1V73 A;  1QHW A;  4F0Z A;  1KBP A;  2Q8U A;  1USH A;  3V4Y A;  2IE3 C;  3IB8 A; 
#chains in the Genus database with same CATH topology
 2XMO A;  1NNW A;  3PSO A;  2JOG A;  1II7 A;  4JA9 A;  1JK7 A;  5JPF A;  4DHL A;  1S95 A;  1G5B A;  5C1V A;  4UT2 A;  3H62 B;  1S3L A;  2P6B A;  4V0X A;  1UF3 A;  2CV9 A;  3IVE A;  3GVE A;  3H67 A;  1OI8 A;  4TUG A;  3RL4 A;  2NXF A;  4MOY A;  4O43 A;  1HO5 A;  3THO B;  1HP1 A;  3FGA C;  2GJU A;  5JPE A;  4ORB A;  1S70 A;  3T1I A;  3EGH A;  3TGH A;  2A22 A;  2KKN A;  4YKE A;  3THN A;  2O8A A;  3AV0 A;  2HYP A;  1M63 A;  3DW8 C;  4IYP C;  3E7A A;  4ORC A;  4KBP A;  2WDF A;  2YVT A;  3H61 A;  3H64 A;  3H60 A;  1Z2W A;  3K7W C;  4J6O A;  1U32 A;  2NYL C;  2BCD A;  3IB7 A;  1SU1 A;  4LAC C;  1UTE A;  2Z72 A;  2Z1A A;  3C9F A;  1TCO A;  2NPP C;  4H2F A;  3DSD A;  4FBK A;  4H1Y P;  2DFJ A;  4H2G A;  4FBW A;  4LTY A;  4Q7F A;  5EQV A;  2R17 A;  3H66 A;  2USH A;  3QG5 C;  4OR9 A;  1Z2X A;  4H2B A;  4V0W A;  4DSY A;  2IAE C;  4IL1 A;  3P71 C;  1FJM A;  5GTU A;  4DT2 A;  1IT6 A;  4UT3 B;  4H1S A;  2WDD A;  3E7B A;  4H2I A;  4I5N C;  5IOH A;  1XZW A;  3DSC A;  3CK2 A;  1XM7 A;  2ZOA A;  3EGG A;  1S8E A;  5B8I A;  3K7V C;  5JJT A;  2DXL A;  4TUI A;  4O24 A;  2AHD A;  3E0J A;  1S3M A;  1WAO 1;  4ZX2 A;  3C5W C;  1QFC A;  3JYF A;  5J28 A;  3H63 A;  2WDE A;  2Z06 A;  3N5U A;  3PSN A;  3ZTV A;  1AUI A;  4NZV A;  3RL3 A;  4HD0 A;  4G9J A;  1T71 A;  2BDX A;  2IE4 C;  3KBP A;  4FCX A;  4ZVZ A;  4XPN A;  2NYM C;  4UT3 A;  1S3N A;  4KKZ A;  2YEQ A;  4LU9 A;  3LL8 A;  4I5L C;  2O8G A;  4FBQ A;  4WWL A;  4V0V A;  3IVD A;  3H69 A;  3ICF A;  2QJC A;  5DNY A;  4O5G A;  4O4K A;  3QFK A;  5F3W A;  4ORA A;  4B2O A;  3HVQ A;  3RL5 A;  1MF8 A;  2WDC A;  3FLO A;  4JA7 A;  3D03 A;  2QFR A;  3QFO A;  2ZO9 B;  2HY1 A;  1HPU A;  1OIE A;  3AUZ A;  4MOV A;  4MP0 A;  3RQZ A;  5INB A;  2HYO A;  1OID A;  4UWQ A;  1WAR A;  2DXN A;  1T70 A;  2BQ8 X;  3QFN A;  3H68 A;  4M0V A;  3ZU0 A;  1W24 A;  2QFP A;  3QFM A;  5HPE A;  2ZBM A;  1V73 A;  1QHW A;  4F0Z A;  1KBP A;  2Q8U A;  1USH A;  3V4Y A;  2IE3 C;  3IB8 A; 
#chains in the Genus database with same CATH homology
 2XMO A;  1NNW A;  3PSO A;  2JOG A;  1II7 A;  4JA9 A;  1JK7 A;  5JPF A;  4DHL A;  1S95 A;  1G5B A;  5C1V A;  4UT2 A;  3H62 B;  1S3L A;  2P6B A;  4V0X A;  1UF3 A;  2CV9 A;  3IVE A;  3GVE A;  3H67 A;  1OI8 A;  4TUG A;  3RL4 A;  2NXF A;  4MOY A;  4O43 A;  1HO5 A;  3THO B;  1HP1 A;  3FGA C;  2GJU A;  5JPE A;  4ORB A;  1S70 A;  3T1I A;  3EGH A;  3TGH A;  2A22 A;  2KKN A;  4YKE A;  3THN A;  2O8A A;  3AV0 A;  2HYP A;  1M63 A;  3DW8 C;  4IYP C;  3E7A A;  4ORC A;  4KBP A;  2WDF A;  2YVT A;  3H61 A;  3H64 A;  3H60 A;  1Z2W A;  3K7W C;  4J6O A;  1U32 A;  2NYL C;  2BCD A;  3IB7 A;  1SU1 A;  4LAC C;  1UTE A;  2Z72 A;  2Z1A A;  3C9F A;  1TCO A;  2NPP C;  4H2F A;  3DSD A;  4FBK A;  4H1Y P;  2DFJ A;  4H2G A;  4FBW A;  4LTY A;  4Q7F A;  5EQV A;  2R17 A;  3H66 A;  2USH A;  3QG5 C;  4OR9 A;  1Z2X A;  4H2B A;  4V0W A;  4DSY A;  2IAE C;  4IL1 A;  3P71 C;  1FJM A;  5GTU A;  4DT2 A;  1IT6 A;  4UT3 B;  4H1S A;  2WDD A;  3E7B A;  4H2I A;  4I5N C;  5IOH A;  1XZW A;  3DSC A;  3CK2 A;  1XM7 A;  2ZOA A;  3EGG A;  1S8E A;  5B8I A;  3K7V C;  5JJT A;  2DXL A;  4TUI A;  4O24 A;  2AHD A;  3E0J A;  1S3M A;  1WAO 1;  4ZX2 A;  3C5W C;  1QFC A;  3JYF A;  5J28 A;  3H63 A;  2WDE A;  2Z06 A;  3N5U A;  3PSN A;  3ZTV A;  1AUI A;  4NZV A;  3RL3 A;  4HD0 A;  4G9J A;  1T71 A;  2BDX A;  2IE4 C;  3KBP A;  4FCX A;  4ZVZ A;  4XPN A;  2NYM C;  4UT3 A;  1S3N A;  4KKZ A;  2YEQ A;  4LU9 A;  3LL8 A;  4I5L C;  2O8G A;  4FBQ A;  4WWL A;  4V0V A;  3IVD A;  3H69 A;  3ICF A;  2QJC A;  5DNY A;  4O5G A;  4O4K A;  3QFK A;  5F3W A;  4ORA A;  4B2O A;  3HVQ A;  3RL5 A;  1MF8 A;  2WDC A;  3FLO A;  4JA7 A;  3D03 A;  2QFR A;  3QFO A;  2ZO9 B;  2HY1 A;  1HPU A;  1OIE A;  3AUZ A;  4MOV A;  4MP0 A;  3RQZ A;  5INB A;  2HYO A;  1OID A;  4UWQ A;  1WAR A;  2DXN A;  1T70 A;  2BQ8 X;  3QFN A;  3H68 A;  4M0V A;  3ZU0 A;  1W24 A;  2QFP A;  3QFM A;  5HPE A;  2ZBM A;  1V73 A;  1QHW A;  4F0Z A;  1KBP A;  2Q8U A;  1USH A;  3V4Y A;  2IE3 C;  3IB8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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