1Z2WA

Crystal structure of mouse vps29 complexed with mn2+
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
182
structure length
182
Chain Sequence
MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly
pubmed doi rcsb
source organism Mus musculus
molecule tags Protein transport
molecule keywords Vacuolar protein sorting 29
total genus 45
structure length 182
sequence length 182
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF12850 Metallophos_2 Calcineurin-like phosphoesterase superfamily domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 1z2wA00
1HPUA 1AUIA 1M63A 4H2BA 3RL5A 4LU9A 4NZVA 5J28A 5JPFA 1G5BA 1S70A 4UT2A 1T71A 3RL4A 4MOYA 3P71C 4UT3B 4IYPC 3RL3A 1TCOA 4OR9A 4I5NC 1UTEA 2QJCA 4MP0A 1QFCA 3AUZA 4DSYA 4O4KA 3ICFA 4ORCA 1IT6A 4B2OA 2DFJA 1Z2XA 4V0VA 5HPEA 3QFOA 4TUGA 1XM7A 4IL1A 2O8GA 2NYLC 4ZX2A 2BQ8X 3PSNA 3HVQA 4TUIA 3H66A 2IE4C 3EGGA 3T1IA 2QFPA 1USHA 3H60A 4JA7A 2WDCA 1OIDA 5B8IA 4O43A 3EGHA 3PSOA 4LACC 1MF8A 4WWLA 1U32A 1S8EA 1T70A 1SU1A 1S3NA 3QFMA 3CK2A 4FCXA 4H2IA 2Z06A 3DW8C 1KBPA 1NNWA 2NPPC 2USHA 4UT3A 3DSDA 4G9JA 3H64A 5DNYA 2R17A 3IVDA 3K7WC 4H2GA 2BCDA 2WDEA 2ZBMA 4I5LC 4JA9A 4ORBA 4HD0A 5JJTA 2AHDA 2Z72A 4J6OA 2WDFA 1WARA 4O24A 1FJMA 4V0XA 4M0VA 2BDXA 3E7AA 4V0WA 4H1YP 3LL8A 2Z1AA 4F0ZA 2GJUA 2IAEC 4ORAA 5C1VA 4H1SA 3H67A 2QFRA 1QHWA 3GVEA 5F3WA 3H68A 2A22A 2YVTA 4LTYA 3C9FA 3QFNA 1II7A 3ZTVA 3C5WC 3ZU0A 1W24A 3QG5C 3THOB 2WDDA 5INBA 1OIEA 1Z2WA 2NYMC 2CV9A 2NXFA 4YKEA 5EQVA 3V4YA 3IVEA 4MOVA 1S3LA 4FBWA 1V73A 3IB8A 1JK7A 2IE3C 2XMOA 4Q7FA 2KKNA 2HYPA 3THNA 1S95A 4FBKA 4KBPA 2HYOA 1HO5A 4DT2A 3E7BA 3TGHA 4DHLA 1XZWA 4H2FA 2JOGA 4O5GA 2Q8UA 3H69A 4KKZA 3QFKA 1UF3A 1WAO1 1OI8A 3H63A 4ZVZA 5JPEA 3RQZA 2O8AA 5IOHA 3KBPA 3DSCA 3H61A 3AV0A 3JYFA 3H62B 3K7VC 5GTUA 4XPNA 2P6BA 3IB7A 3FGAC 3N5UA 2HY1A 4UWQA 1S3MA 4FBQA 1HP1A
chains in the Genus database with same CATH superfamily
1HPUA 1AUIA 1M63A 4H2BA 3RL5A 4LU9A 4NZVA 5J28A 5JPFA 1G5BA 1S70A 4UT2A 1T71A 3FLOA 3RL4A 4MOYA 3P71C 4UT3B 4IYPC 3RL3A 1TCOA 4OR9A 4I5NC 1UTEA 2QJCA 4MP0A 1QFCA 3AUZA 4DSYA 4O4KA 3ICFA 4ORCA 1IT6A 4B2OA 2DFJA 1Z2XA 4V0VA 5HPEA 3QFOA 4TUGA 1XM7A 4IL1A 2O8GA 2NYLC 4ZX2A 2BQ8X 3PSNA 3HVQA 4TUIA 3H66A 2IE4C 3EGGA 3T1IA 2QFPA 1USHA 3H60A 4JA7A 2WDCA 1OIDA 5B8IA 4O43A 3EGHA 3PSOA 4LACC 1MF8A 4WWLA 1U32A 1S8EA 1T70A 1SU1A 1S3NA 3QFMA 3CK2A 4FCXA 3E0JA 2DXNA 2Z06A 3DW8C 4H2IA 1KBPA 1NNWA 2NPPC 2USHA 4UT3A 3DSDA 4G9JA 3H64A 5DNYA 2R17A 3IVDA 3K7WC 4H2GA 2BCDA 2WDEA 2ZBMA 4I5LC 4JA9A 4ORBA 4HD0A 5JJTA 2AHDA 2Z72A 4J6OA 2WDFA 1WARA 4O24A 1FJMA 4V0XA 4M0VA 2BDXA 3E7AA 4V0WA 4H1YP 3LL8A 2Z1AA 4F0ZA 2GJUA 2IAEC 4ORAA 5C1VA 4H1SA 3H67A 2QFRA 1QHWA 3GVEA 5F3WA 3H68A 2A22A 2YVTA 4LTYA 3C9FA 3QFNA 2DXLA 1II7A 3ZTVA 3C5WC 3ZU0A 1W24A 3QG5C 3THOB 2WDDA 5INBA 1OIEA 1Z2WA 2NYMC 2ZOAA 2CV9A 2NXFA 4YKEA 5EQVA 3V4YA 3IVEA 4MOVA 1S3LA 4FBWA 1V73A 3IB8A 1JK7A 2IE3C 2XMOA 4Q7FA 2KKNA 2HYPA 3THNA 1S95A 4FBKA 4KBPA 2HYOA 1HO5A 4DT2A 3D03A 2YEQA 3E7BA 3TGHA 4DHLA 1XZWA 4H2FA 2JOGA 4O5GA 2Q8UA 3H69A 4KKZA 3QFKA 1UF3A 1WAO1 1OI8A 3H63A 4ZVZA 5JPEA 3RQZA 2O8AA 5IOHA 3KBPA 3DSCA 3H61A 3AV0A 3JYFA 3H62B 3K7VC 5GTUA 4XPNA 2P6BA 3IB7A 3FGAC 2ZO9B 3N5UA 2HY1A 4UWQA 1S3MA 4FBQA 1HP1A
chains in the Genus database with same CATH topology
1HPUA 1AUIA 1M63A 4H2BA 3RL5A 4LU9A 4NZVA 5J28A 5JPFA 1G5BA 1S70A 4UT2A 1T71A 3FLOA 3RL4A 4MOYA 3P71C 4UT3B 4IYPC 3RL3A 1TCOA 4OR9A 4I5NC 1UTEA 2QJCA 4MP0A 1QFCA 3AUZA 4DSYA 4O4KA 3ICFA 4ORCA 1IT6A 4B2OA 2DFJA 1Z2XA 4V0VA 5HPEA 3QFOA 4TUGA 1XM7A 4IL1A 2O8GA 2NYLC 4ZX2A 2BQ8X 3PSNA 3HVQA 4TUIA 3H66A 2IE4C 3EGGA 3T1IA 2QFPA 1USHA 3H60A 4JA7A 2WDCA 1OIDA 5B8IA 4O43A 3EGHA 3PSOA 4LACC 1MF8A 4WWLA 1U32A 1S8EA 1T70A 1SU1A 1S3NA 3QFMA 3CK2A 4FCXA 3E0JA 2DXNA 2Z06A 3DW8C 4H2IA 1KBPA 1NNWA 2NPPC 2USHA 4UT3A 3DSDA 4G9JA 3H64A 5DNYA 2R17A 3IVDA 3K7WC 4H2GA 2BCDA 2WDEA 2ZBMA 4I5LC 4JA9A 4ORBA 4HD0A 5JJTA 2AHDA 2Z72A 4J6OA 2WDFA 1WARA 4O24A 1FJMA 4V0XA 4M0VA 2BDXA 3E7AA 4V0WA 4H1YP 3LL8A 2Z1AA 4F0ZA 2GJUA 2IAEC 4ORAA 5C1VA 4H1SA 3H67A 2QFRA 1QHWA 3GVEA 5F3WA 3H68A 2A22A 2YVTA 4LTYA 3C9FA 3QFNA 2DXLA 1II7A 3ZTVA 3C5WC 3ZU0A 1W24A 3QG5C 3THOB 2WDDA 5INBA 1OIEA 1Z2WA 2NYMC 2ZOAA 2CV9A 2NXFA 4YKEA 5EQVA 3V4YA 3IVEA 4MOVA 1S3LA 4FBWA 1V73A 3IB8A 1JK7A 2IE3C 2XMOA 4Q7FA 2KKNA 2HYPA 3THNA 1S95A 4FBKA 4KBPA 2HYOA 1HO5A 4DT2A 3D03A 2YEQA 3E7BA 3TGHA 4DHLA 1XZWA 4H2FA 2JOGA 4O5GA 2Q8UA 3H69A 4KKZA 3QFKA 1UF3A 1WAO1 1OI8A 3H63A 4ZVZA 5JPEA 3RQZA 2O8AA 5IOHA 3KBPA 3DSCA 3H61A 3AV0A 3JYFA 3H62B 3K7VC 5GTUA 4XPNA 2P6BA 3IB7A 3FGAC 2ZO9B 3N5UA 2HY1A 4UWQA 1S3MA 4FBQA 1HP1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HPU A;  1AUI A;  1M63 A;  4H2B A;  3RL5 A;  4LU9 A;  4NZV A;  5J28 A;  5JPF A;  1G5B A;  1S70 A;  4UT2 A;  1T71 A;  3RL4 A;  4MOY A;  3P71 C;  4UT3 B;  4IYP C;  3RL3 A;  1TCO A;  4OR9 A;  4I5N C;  1UTE A;  2QJC A;  4MP0 A;  1QFC A;  3AUZ A;  4DSY A;  4O4K A;  3ICF A;  4ORC A;  1IT6 A;  4B2O A;  2DFJ A;  1Z2X A;  4V0V A;  5HPE A;  3QFO A;  4TUG A;  1XM7 A;  4IL1 A;  2O8G A;  2NYL C;  4ZX2 A;  2BQ8 X;  3PSN A;  3HVQ A;  4TUI A;  3H66 A;  2IE4 C;  3EGG A;  3T1I A;  2QFP A;  1USH A;  3H60 A;  4JA7 A;  2WDC A;  1OID A;  5B8I A;  4O43 A;  3EGH A;  3PSO A;  4LAC C;  1MF8 A;  4WWL A;  1U32 A;  1S8E A;  1T70 A;  1SU1 A;  1S3N A;  3QFM A;  3CK2 A;  4FCX A;  4H2I A;  2Z06 A;  3DW8 C;  1KBP A;  1NNW A;  2NPP C;  2USH A;  4UT3 A;  3DSD A;  4G9J A;  3H64 A;  5DNY A;  2R17 A;  3IVD A;  3K7W C;  4H2G A;  2BCD A;  2WDE A;  2ZBM A;  4I5L C;  4JA9 A;  4ORB A;  4HD0 A;  5JJT A;  2AHD A;  2Z72 A;  4J6O A;  2WDF A;  1WAR A;  4O24 A;  1FJM A;  4V0X A;  4M0V A;  2BDX A;  3E7A A;  4V0W A;  4H1Y P;  3LL8 A;  2Z1A A;  4F0Z A;  2GJU A;  2IAE C;  4ORA A;  5C1V A;  4H1S A;  3H67 A;  2QFR A;  1QHW A;  3GVE A;  5F3W A;  3H68 A;  2A22 A;  2YVT A;  4LTY A;  3C9F A;  3QFN A;  1II7 A;  3ZTV A;  3C5W C;  3ZU0 A;  1W24 A;  3QG5 C;  3THO B;  2WDD A;  5INB A;  1OIE A;  1Z2W A;  2NYM C;  2CV9 A;  2NXF A;  4YKE A;  5EQV A;  3V4Y A;  3IVE A;  4MOV A;  1S3L A;  4FBW A;  1V73 A;  3IB8 A;  1JK7 A;  2IE3 C;  2XMO A;  4Q7F A;  2KKN A;  2HYP A;  3THN A;  1S95 A;  4FBK A;  4KBP A;  2HYO A;  1HO5 A;  4DT2 A;  3E7B A;  3TGH A;  4DHL A;  1XZW A;  4H2F A;  2JOG A;  4O5G A;  2Q8U A;  3H69 A;  4KKZ A;  3QFK A;  1UF3 A;  1WAO 1;  1OI8 A;  3H63 A;  4ZVZ A;  5JPE A;  3RQZ A;  2O8A A;  5IOH A;  3KBP A;  3DSC A;  3H61 A;  3AV0 A;  3JYF A;  3H62 B;  3K7V C;  5GTU A;  4XPN A;  2P6B A;  3IB7 A;  3FGA C;  3N5U A;  2HY1 A;  4UWQ A;  1S3M A;  4FBQ A;  1HP1 A; 
#chains in the Genus database with same CATH topology
 1HPU A;  1AUI A;  1M63 A;  4H2B A;  3RL5 A;  4LU9 A;  4NZV A;  5J28 A;  5JPF A;  1G5B A;  1S70 A;  4UT2 A;  1T71 A;  3FLO A;  3RL4 A;  4MOY A;  3P71 C;  4UT3 B;  4IYP C;  3RL3 A;  1TCO A;  4OR9 A;  4I5N C;  1UTE A;  2QJC A;  4MP0 A;  1QFC A;  3AUZ A;  4DSY A;  4O4K A;  3ICF A;  4ORC A;  1IT6 A;  4B2O A;  2DFJ A;  1Z2X A;  4V0V A;  5HPE A;  3QFO A;  4TUG A;  1XM7 A;  4IL1 A;  2O8G A;  2NYL C;  4ZX2 A;  2BQ8 X;  3PSN A;  3HVQ A;  4TUI A;  3H66 A;  2IE4 C;  3EGG A;  3T1I A;  2QFP A;  1USH A;  3H60 A;  4JA7 A;  2WDC A;  1OID A;  5B8I A;  4O43 A;  3EGH A;  3PSO A;  4LAC C;  1MF8 A;  4WWL A;  1U32 A;  1S8E A;  1T70 A;  1SU1 A;  1S3N A;  3QFM A;  3CK2 A;  4FCX A;  3E0J A;  2DXN A;  2Z06 A;  3DW8 C;  4H2I A;  1KBP A;  1NNW A;  2NPP C;  2USH A;  4UT3 A;  3DSD A;  4G9J A;  3H64 A;  5DNY A;  2R17 A;  3IVD A;  3K7W C;  4H2G A;  2BCD A;  2WDE A;  2ZBM A;  4I5L C;  4JA9 A;  4ORB A;  4HD0 A;  5JJT A;  2AHD A;  2Z72 A;  4J6O A;  2WDF A;  1WAR A;  4O24 A;  1FJM A;  4V0X A;  4M0V A;  2BDX A;  3E7A A;  4V0W A;  4H1Y P;  3LL8 A;  2Z1A A;  4F0Z A;  2GJU A;  2IAE C;  4ORA A;  5C1V A;  4H1S A;  3H67 A;  2QFR A;  1QHW A;  3GVE A;  5F3W A;  3H68 A;  2A22 A;  2YVT A;  4LTY A;  3C9F A;  3QFN A;  2DXL A;  1II7 A;  3ZTV A;  3C5W C;  3ZU0 A;  1W24 A;  3QG5 C;  3THO B;  2WDD A;  5INB A;  1OIE A;  1Z2W A;  2NYM C;  2ZOA A;  2CV9 A;  2NXF A;  4YKE A;  5EQV A;  3V4Y A;  3IVE A;  4MOV A;  1S3L A;  4FBW A;  1V73 A;  3IB8 A;  1JK7 A;  2IE3 C;  2XMO A;  4Q7F A;  2KKN A;  2HYP A;  3THN A;  1S95 A;  4FBK A;  4KBP A;  2HYO A;  1HO5 A;  4DT2 A;  3D03 A;  2YEQ A;  3E7B A;  3TGH A;  4DHL A;  1XZW A;  4H2F A;  2JOG A;  4O5G A;  2Q8U A;  3H69 A;  4KKZ A;  3QFK A;  1UF3 A;  1WAO 1;  1OI8 A;  3H63 A;  4ZVZ A;  5JPE A;  3RQZ A;  2O8A A;  5IOH A;  3KBP A;  3DSC A;  3H61 A;  3AV0 A;  3JYF A;  3H62 B;  3K7V C;  5GTU A;  4XPN A;  2P6B A;  3IB7 A;  3FGA C;  2ZO9 B;  3N5U A;  2HY1 A;  4UWQ A;  1S3M A;  4FBQ A;  1HP1 A; 
#chains in the Genus database with same CATH homology
 1HPU A;  1AUI A;  1M63 A;  4H2B A;  3RL5 A;  4LU9 A;  4NZV A;  5J28 A;  5JPF A;  1G5B A;  1S70 A;  4UT2 A;  1T71 A;  3FLO A;  3RL4 A;  4MOY A;  3P71 C;  4UT3 B;  4IYP C;  3RL3 A;  1TCO A;  4OR9 A;  4I5N C;  1UTE A;  2QJC A;  4MP0 A;  1QFC A;  3AUZ A;  4DSY A;  4O4K A;  3ICF A;  4ORC A;  1IT6 A;  4B2O A;  2DFJ A;  1Z2X A;  4V0V A;  5HPE A;  3QFO A;  4TUG A;  1XM7 A;  4IL1 A;  2O8G A;  2NYL C;  4ZX2 A;  2BQ8 X;  3PSN A;  3HVQ A;  4TUI A;  3H66 A;  2IE4 C;  3EGG A;  3T1I A;  2QFP A;  1USH A;  3H60 A;  4JA7 A;  2WDC A;  1OID A;  5B8I A;  4O43 A;  3EGH A;  3PSO A;  4LAC C;  1MF8 A;  4WWL A;  1U32 A;  1S8E A;  1T70 A;  1SU1 A;  1S3N A;  3QFM A;  3CK2 A;  4FCX A;  3E0J A;  2DXN A;  2Z06 A;  3DW8 C;  4H2I A;  1KBP A;  1NNW A;  2NPP C;  2USH A;  4UT3 A;  3DSD A;  4G9J A;  3H64 A;  5DNY A;  2R17 A;  3IVD A;  3K7W C;  4H2G A;  2BCD A;  2WDE A;  2ZBM A;  4I5L C;  4JA9 A;  4ORB A;  4HD0 A;  5JJT A;  2AHD A;  2Z72 A;  4J6O A;  2WDF A;  1WAR A;  4O24 A;  1FJM A;  4V0X A;  4M0V A;  2BDX A;  3E7A A;  4V0W A;  4H1Y P;  3LL8 A;  2Z1A A;  4F0Z A;  2GJU A;  2IAE C;  4ORA A;  5C1V A;  4H1S A;  3H67 A;  2QFR A;  1QHW A;  3GVE A;  5F3W A;  3H68 A;  2A22 A;  2YVT A;  4LTY A;  3C9F A;  3QFN A;  2DXL A;  1II7 A;  3ZTV A;  3C5W C;  3ZU0 A;  1W24 A;  3QG5 C;  3THO B;  2WDD A;  5INB A;  1OIE A;  1Z2W A;  2NYM C;  2ZOA A;  2CV9 A;  2NXF A;  4YKE A;  5EQV A;  3V4Y A;  3IVE A;  4MOV A;  1S3L A;  4FBW A;  1V73 A;  3IB8 A;  1JK7 A;  2IE3 C;  2XMO A;  4Q7F A;  2KKN A;  2HYP A;  3THN A;  1S95 A;  4FBK A;  4KBP A;  2HYO A;  1HO5 A;  4DT2 A;  3D03 A;  2YEQ A;  3E7B A;  3TGH A;  4DHL A;  1XZW A;  4H2F A;  2JOG A;  4O5G A;  2Q8U A;  3H69 A;  4KKZ A;  3QFK A;  1UF3 A;  1WAO 1;  1OI8 A;  3H63 A;  4ZVZ A;  5JPE A;  3RQZ A;  2O8A A;  5IOH A;  3KBP A;  3DSC A;  3H61 A;  3AV0 A;  3JYF A;  3H62 B;  3K7V C;  5GTU A;  4XPN A;  2P6B A;  3IB7 A;  3FGA C;  2ZO9 B;  3N5U A;  2HY1 A;  4UWQ A;  1S3M A;  4FBQ A;  1HP1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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