3FLOA

Crystal structure of the carboxyl-terminal domain of yeast dna polymerase alpha in complex with its b subunit
Total Genus 123
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
123
sequence length
458
structure length
433
Chain Sequence
RTMRQNLQEASDVLDDQIESFTKIIQNHYKLSPNDFADPTIQSQSEIYAVGRIVPDSPTYDKFLNPESLSLETSRMGGVGRRVRLDLSQVNELSFFLGQIVAFKGKNANGDYFTVNSILPLPYPNSPVSTSQELQEFQANLEGSSLKVIVTCGPYFANDNFSLELLQEFIDSINNEVKPHVLIMFGPFIDITHPLIASGKLPNFPQFKTQPKTLDELFLKLFTPILKTISPHIQTVLIPSTKDAISNHAAYPQASLIRKALQLPKRNFKCMANPSSFQINEIYFGCSNVDTFKDLKEVIKGGTTSSRYRLDRVSEHILQQRRYYPIFPGSIRTHISGADLDVSYLGLTEFVGGFSPDIMIIPSELQHFARVVQNVVVINPGRFIRATGNRGSYAQITVQCPDLEDGKLTLVEGEEPVYLHNVWKRARVDLIAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords DNA polymerase alpha subunit B
publication title 3D architecture of DNA Pol alpha reveals the functional core of multi-subunit replicative polymerases
pubmed doi rcsb
source organism Saccharomyces cerevisiae
total genus 123
structure length 433
sequence length 458
chains with identical sequence C, E, G
ec nomenclature
pdb deposition date 2008-12-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04042 DNA_pol_E_B DNA polymerase alpha/epsilon subunit B
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.60 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3floA02
3FLOA
chains in the Genus database with same CATH superfamily
4H1SA 3TGHA 1JK7A 1UTEA 3QFNA 1FJMA 5JPEA 3RL4A 4H2IA 4IL1A 3RQZA 2A22A 2P6BA 4V0WA 3H66A 4WWLA 3H61A 1S95A 4O4KA 3QFMA 4Q7FA 1UF3A 5J28A 4O5GA 3H62B 4FBQA 1S3LA 1S70A 2GJUA 4F0ZA 5JPFA 4TUGA 3T1IA 1T70A 4B2OA 2Z1AA 4O43A 3C5WC 3PSOA 2IE3C 1V73A 1NNWA 3H64A 1HPUA 3JYFA 3ICFA 3D03A 4ORBA 3RL5A 2NPPC 4UWQA 5EQVA 4V0XA 4XPNA 2Z72A 1HO5A 4ZX2A 4MOVA 3E7AA 3C9FA 2WDEA 4MP0A 4FCXA 3LL8A 4DSYA 1XZWA 1HP1A 4H2BA 2HYPA 3DSDA 3QFKA 2Q8UA 4MOYA 1MF8A 2USHA 4I5NC 3QFOA 2IAEC 4LACC 1S8EA 4FBKA 1QHWA 2BDXA 2WDFA 3IVEA 4J6OA 2JOGA 3IB7A 4O24A 5F3WA 3V4YA 3AUZA 4ORCA 1USHA 4KBPA 4LU9A 1OIDA 2QJCA 3H67A 1II7A 2NXFA 3GVEA 2O8GA 2Z06A 4V0VA 4FBWA 5B8IA 1OIEA 2WDCA 2DFJA 3THOB 3EGHA 2WDDA 3K7VC 3CK2A 3EGGA 1SU1A 1WARA 4DT2A 5GTUA 3AV0A 4NZVA 3HVQA 4JA9A 2ZO9B 2ZBMA 1QFCA 2YEQA 3IB8A 5HPEA 1IT6A 1Z2XA 1WAO1 3P71C 1XM7A 3RL3A 1KBPA 2BCDA 2XMOA 3PSNA 4H2GA 4JA7A 2IE4C 3ZU0A 4ORAA 3FLOA 3H63A 1T71A 2QFRA 3H68A 1G5BA 4G9JA 4KKZA 3FGAC 2KKNA 1U32A 1M63A 4I5LC 3N5UA 3KBPA 4LTYA 5DNYA 2R17A 3E7BA 4ZVZA 2CV9A 2YVTA 1TCOA 3DW8C 3H69A 1S3MA 1W24A 3ZTVA 4IYPC 4YKEA 2AHDA 1Z2WA 4UT3B 3THNA 3K7WC 2ZOAA 2QFPA 4UT2A 4UT3A 1S3NA 3QG5C 2HY1A 4H1YP 1AUIA 4M0VA 5JJTA 2NYLC 2BQ8X 3DSCA 5C1VA 4H2FA 3E0JA 1OI8A 2DXNA 4DHLA 2HYOA 2NYMC 3H60A 4HD0A 5INBA 4TUIA 5IOHA 2O8AA 4OR9A 3IVDA 2DXLA
chains in the Genus database with same CATH topology
4H1SA 3TGHA 1JK7A 1UTEA 3QFNA 1FJMA 5JPEA 3RL4A 4H2IA 4IL1A 3RQZA 2A22A 2P6BA 4V0WA 3H66A 4WWLA 3H61A 1S95A 4O4KA 3QFMA 4Q7FA 1UF3A 5J28A 4O5GA 3H62B 4FBQA 1S3LA 1S70A 2GJUA 4F0ZA 5JPFA 4TUGA 3T1IA 1T70A 4B2OA 2Z1AA 4O43A 3C5WC 3PSOA 2IE3C 1V73A 1NNWA 3H64A 1HPUA 3JYFA 3ICFA 3D03A 4ORBA 3RL5A 2NPPC 4UWQA 5EQVA 4V0XA 4XPNA 2Z72A 1HO5A 4ZX2A 4MOVA 3E7AA 3C9FA 2WDEA 4MP0A 4FCXA 3LL8A 4DSYA 1XZWA 1HP1A 4H2BA 2HYPA 3DSDA 3QFKA 2Q8UA 4MOYA 1MF8A 2USHA 4I5NC 3QFOA 2IAEC 4LACC 1S8EA 4FBKA 1QHWA 2BDXA 2WDFA 3IVEA 4J6OA 2JOGA 3IB7A 4O24A 5F3WA 3V4YA 3AUZA 4ORCA 1USHA 4KBPA 4LU9A 1OIDA 2QJCA 3H67A 1II7A 2NXFA 3GVEA 2O8GA 2Z06A 4V0VA 4FBWA 5B8IA 1OIEA 2WDCA 2DFJA 3THOB 3EGHA 2WDDA 3K7VC 3CK2A 3EGGA 1SU1A 1WARA 4DT2A 5GTUA 3AV0A 4NZVA 3HVQA 4JA9A 2ZO9B 2ZBMA 1QFCA 2YEQA 3IB8A 5HPEA 1IT6A 1Z2XA 1WAO1 3P71C 1XM7A 3RL3A 1KBPA 2BCDA 2XMOA 3PSNA 4H2GA 4JA7A 2IE4C 3ZU0A 4ORAA 3FLOA 3H63A 1T71A 2QFRA 3H68A 1G5BA 4G9JA 4KKZA 3FGAC 2KKNA 1U32A 1M63A 4I5LC 3N5UA 3KBPA 4LTYA 5DNYA 2R17A 3E7BA 4ZVZA 2CV9A 2YVTA 1TCOA 3DW8C 3H69A 1S3MA 1W24A 3ZTVA 4IYPC 4YKEA 2AHDA 1Z2WA 4UT3B 3THNA 3K7WC 2ZOAA 2QFPA 4UT2A 4UT3A 1S3NA 3QG5C 2HY1A 4H1YP 1AUIA 4M0VA 5JJTA 2NYLC 2BQ8X 3DSCA 5C1VA 4H2FA 3E0JA 1OI8A 2DXNA 4DHLA 2HYOA 2NYMC 3H60A 4HD0A 5INBA 4TUIA 5IOHA 2O8AA 4OR9A 3IVDA 2DXLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FLO A; 
#chains in the Genus database with same CATH topology
 4H1S A;  3TGH A;  1JK7 A;  1UTE A;  3QFN A;  1FJM A;  5JPE A;  3RL4 A;  4H2I A;  4IL1 A;  3RQZ A;  2A22 A;  2P6B A;  4V0W A;  3H66 A;  4WWL A;  3H61 A;  1S95 A;  4O4K A;  3QFM A;  4Q7F A;  1UF3 A;  5J28 A;  4O5G A;  3H62 B;  4FBQ A;  1S3L A;  1S70 A;  2GJU A;  4F0Z A;  5JPF A;  4TUG A;  3T1I A;  1T70 A;  4B2O A;  2Z1A A;  4O43 A;  3C5W C;  3PSO A;  2IE3 C;  1V73 A;  1NNW A;  3H64 A;  1HPU A;  3JYF A;  3ICF A;  3D03 A;  4ORB A;  3RL5 A;  2NPP C;  4UWQ A;  5EQV A;  4V0X A;  4XPN A;  2Z72 A;  1HO5 A;  4ZX2 A;  4MOV A;  3E7A A;  3C9F A;  2WDE A;  4MP0 A;  4FCX A;  3LL8 A;  4DSY A;  1XZW A;  1HP1 A;  4H2B A;  2HYP A;  3DSD A;  3QFK A;  2Q8U A;  4MOY A;  1MF8 A;  2USH A;  4I5N C;  3QFO A;  2IAE C;  4LAC C;  1S8E A;  4FBK A;  1QHW A;  2BDX A;  2WDF A;  3IVE A;  4J6O A;  2JOG A;  3IB7 A;  4O24 A;  5F3W A;  3V4Y A;  3AUZ A;  4ORC A;  1USH A;  4KBP A;  4LU9 A;  1OID A;  2QJC A;  3H67 A;  1II7 A;  2NXF A;  3GVE A;  2O8G A;  2Z06 A;  4V0V A;  4FBW A;  5B8I A;  1OIE A;  2WDC A;  2DFJ A;  3THO B;  3EGH A;  2WDD A;  3K7V C;  3CK2 A;  3EGG A;  1SU1 A;  1WAR A;  4DT2 A;  5GTU A;  3AV0 A;  4NZV A;  3HVQ A;  4JA9 A;  2ZO9 B;  2ZBM A;  1QFC A;  2YEQ A;  3IB8 A;  5HPE A;  1IT6 A;  1Z2X A;  1WAO 1;  3P71 C;  1XM7 A;  3RL3 A;  1KBP A;  2BCD A;  2XMO A;  3PSN A;  4H2G A;  4JA7 A;  2IE4 C;  3ZU0 A;  4ORA A;  3FLO A;  3H63 A;  1T71 A;  2QFR A;  3H68 A;  1G5B A;  4G9J A;  4KKZ A;  3FGA C;  2KKN A;  1U32 A;  1M63 A;  4I5L C;  3N5U A;  3KBP A;  4LTY A;  5DNY A;  2R17 A;  3E7B A;  4ZVZ A;  2CV9 A;  2YVT A;  1TCO A;  3DW8 C;  3H69 A;  1S3M A;  1W24 A;  3ZTV A;  4IYP C;  4YKE A;  2AHD A;  1Z2W A;  4UT3 B;  3THN A;  3K7W C;  2ZOA A;  2QFP A;  4UT2 A;  4UT3 A;  1S3N A;  3QG5 C;  2HY1 A;  4H1Y P;  1AUI A;  4M0V A;  5JJT A;  2NYL C;  2BQ8 X;  3DSC A;  5C1V A;  4H2F A;  3E0J A;  1OI8 A;  2DXN A;  4DHL A;  2HYO A;  2NYM C;  3H60 A;  4HD0 A;  5INB A;  4TUI A;  5IOH A;  2O8A A;  4OR9 A;  3IVD A;  2DXL A; 
#chains in the Genus database with same CATH homology
 4H1S A;  3TGH A;  1JK7 A;  1UTE A;  3QFN A;  1FJM A;  5JPE A;  3RL4 A;  4H2I A;  4IL1 A;  3RQZ A;  2A22 A;  2P6B A;  4V0W A;  3H66 A;  4WWL A;  3H61 A;  1S95 A;  4O4K A;  3QFM A;  4Q7F A;  1UF3 A;  5J28 A;  4O5G A;  3H62 B;  4FBQ A;  1S3L A;  1S70 A;  2GJU A;  4F0Z A;  5JPF A;  4TUG A;  3T1I A;  1T70 A;  4B2O A;  2Z1A A;  4O43 A;  3C5W C;  3PSO A;  2IE3 C;  1V73 A;  1NNW A;  3H64 A;  1HPU A;  3JYF A;  3ICF A;  3D03 A;  4ORB A;  3RL5 A;  2NPP C;  4UWQ A;  5EQV A;  4V0X A;  4XPN A;  2Z72 A;  1HO5 A;  4ZX2 A;  4MOV A;  3E7A A;  3C9F A;  2WDE A;  4MP0 A;  4FCX A;  3LL8 A;  4DSY A;  1XZW A;  1HP1 A;  4H2B A;  2HYP A;  3DSD A;  3QFK A;  2Q8U A;  4MOY A;  1MF8 A;  2USH A;  4I5N C;  3QFO A;  2IAE C;  4LAC C;  1S8E A;  4FBK A;  1QHW A;  2BDX A;  2WDF A;  3IVE A;  4J6O A;  2JOG A;  3IB7 A;  4O24 A;  5F3W A;  3V4Y A;  3AUZ A;  4ORC A;  1USH A;  4KBP A;  4LU9 A;  1OID A;  2QJC A;  3H67 A;  1II7 A;  2NXF A;  3GVE A;  2O8G A;  2Z06 A;  4V0V A;  4FBW A;  5B8I A;  1OIE A;  2WDC A;  2DFJ A;  3THO B;  3EGH A;  2WDD A;  3K7V C;  3CK2 A;  3EGG A;  1SU1 A;  1WAR A;  4DT2 A;  5GTU A;  3AV0 A;  4NZV A;  3HVQ A;  4JA9 A;  2ZO9 B;  2ZBM A;  1QFC A;  2YEQ A;  3IB8 A;  5HPE A;  1IT6 A;  1Z2X A;  1WAO 1;  3P71 C;  1XM7 A;  3RL3 A;  1KBP A;  2BCD A;  2XMO A;  3PSN A;  4H2G A;  4JA7 A;  2IE4 C;  3ZU0 A;  4ORA A;  3FLO A;  3H63 A;  1T71 A;  2QFR A;  3H68 A;  1G5B A;  4G9J A;  4KKZ A;  3FGA C;  2KKN A;  1U32 A;  1M63 A;  4I5L C;  3N5U A;  3KBP A;  4LTY A;  5DNY A;  2R17 A;  3E7B A;  4ZVZ A;  2CV9 A;  2YVT A;  1TCO A;  3DW8 C;  3H69 A;  1S3M A;  1W24 A;  3ZTV A;  4IYP C;  4YKE A;  2AHD A;  1Z2W A;  4UT3 B;  3THN A;  3K7W C;  2ZOA A;  2QFP A;  4UT2 A;  4UT3 A;  1S3N A;  3QG5 C;  2HY1 A;  4H1Y P;  1AUI A;  4M0V A;  5JJT A;  2NYL C;  2BQ8 X;  3DSC A;  5C1V A;  4H2F A;  3E0J A;  1OI8 A;  2DXN A;  4DHL A;  2HYO A;  2NYM C;  3H60 A;  4HD0 A;  5INB A;  4TUI A;  5IOH A;  2O8A A;  4OR9 A;  3IVD A;  2DXL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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