3FLOA

Crystal structure of the carboxyl-terminal domain of yeast dna polymerase alpha in complex with its b subunit
Total Genus 123
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
123
sequence length
458
structure length
433
Chain Sequence
RTMRQNLQEASDVLDDQIESFTKIIQNHYKLSPNDFADPTIQSQSEIYAVGRIVPDSPTYDKFLNPESLSLETSRMGGVGRRVRLDLSQVNELSFFLGQIVAFKGKNANGDYFTVNSILPLPYPNSPVSTSQELQEFQANLEGSSLKVIVTCGPYFANDNFSLELLQEFIDSINNEVKPHVLIMFGPFIDITHPLIASGKLPNFPQFKTQPKTLDELFLKLFTPILKTISPHIQTVLIPSTKDAISNHAAYPQASLIRKALQLPKRNFKCMANPSSFQINEIYFGCSNVDTFKDLKEVIKGGTTSSRYRLDRVSEHILQQRRYYPIFPGSIRTHISGADLDVSYLGLTEFVGGFSPDIMIIPSELQHFARVVQNVVVINPGRFIRATGNRGSYAQITVQCPDLEDGKLTLVEGEEPVYLHNVWKRARVDLIAS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title 3D architecture of DNA Pol alpha reveals the functional core of multi-subunit replicative polymerases
pubmed doi rcsb
source organism Saccharomyces cerevisiae
molecule tags Transferase
molecule keywords DNA polymerase alpha subunit B
total genus 123
structure length 433
sequence length 458
chains with identical sequence C, E, G
ec nomenclature
pdb deposition date 2008-12-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04042 DNA_pol_E_B DNA polymerase alpha/epsilon subunit B
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.60 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3floA02
3FLOA
chains in the Genus database with same CATH superfamily
2USHA 3H66A 1S3MA 4H2IA 4HD0A 4F0ZA 2WDDA 4JA9A 4LU9A 3RL5A 4FCXA 5F3WA 1JK7A 2BQ8X 3ZTVA 1S8EA 2BDXA 3THOB 3IVDA 3QFOA 1XZWA 3IVEA 5EQVA 4FBQA 2BCDA 5JPFA 3HVQA 3P71C 2CV9A 2QJCA 2YVTA 4OR9A 1Z2WA 4TUGA 3PSOA 4H1YP 1OI8A 4H1SA 2GJUA 3K7VC 2IAEC 4DHLA 4UT3A 1S3NA 1M63A 3EGGA 3RL3A 3AV0A 1NNWA 4ORAA 2Q8UA 3QG5C 4FBWA 3LL8A 2O8AA 3E0JA 4JA7A 4O4KA 2Z72A 3QFMA 3N5UA 4LTYA 3H64A 3IB8A 3V4YA 4UT3B 4FBKA 3TGHA 3PSNA 1TCOA 1XM7A 2Z06A 3CK2A 3H61A 4ZX2A 3DSCA 1S70A 2HYPA 1WARA 2WDCA 2ZO9B 4M0VA 2XMOA 3K7WC 1S95A 1UF3A 4O24A 1V73A 2QFRA 3KBPA 1SU1A 2NXFA 2WDFA 3DW8C 3E7AA 4O5GA 5JPEA 2DXLA 4B2OA 5INBA 1IT6A 1AUIA 1U32A 3FLOA 3H69A 2P6BA 1USHA 5DNYA 5IOHA 1OIDA 3IB7A 5C1VA 1Z2XA 2ZOAA 4NZVA 1S3LA 1KBPA 4DSYA 1T71A 3C9FA 3EGHA 2ZBMA 2A22A 3ZU0A 5J28A 1G5BA 1HPUA 4I5LC 4KKZA 2IE4C 4XPNA 2NPPC 3H60A 4DT2A 3H67A 4ORCA 3ICFA 2HYOA 3H63A 1HO5A 2AHDA 1W24A 1QFCA 3AUZA 4MOYA 4V0WA 3RL4A 4ZVZA 4UT2A 4G9JA 3FGAC 5B8IA 3C5WC 1II7A 2YEQA 1T70A 3THNA 4IYPC 2QFPA 5HPEA 1UTEA 3T1IA 2KKNA 4MOVA 2DFJA 3D03A 4V0XA 4KBPA 2HY1A 5GTUA 3GVEA 4H2GA 4I5NC 4IL1A 3QFKA 2DXNA 4ORBA 2NYLC 3H62B 4TUIA 2Z1AA 4LACC 5JJTA 3DSDA 1FJMA 1HP1A 2R17A 4V0VA 1WAO1 3RQZA 4YKEA 3H68A 2JOGA 4MP0A 4O43A 2O8GA 4H2FA 4Q7FA 4J6OA 1QHWA 1MF8A 3E7BA 2IE3C 2NYMC 2WDEA 3JYFA 4WWLA 1OIEA 3QFNA 4H2BA 4UWQA
chains in the Genus database with same CATH topology
2USHA 3H66A 1S3MA 4H2IA 4HD0A 4F0ZA 2WDDA 4JA9A 4LU9A 3RL5A 4FCXA 5F3WA 1JK7A 2BQ8X 3ZTVA 1S8EA 2BDXA 3THOB 3IVDA 3QFOA 1XZWA 3IVEA 5EQVA 4FBQA 2BCDA 5JPFA 3HVQA 3P71C 2CV9A 2QJCA 2YVTA 4OR9A 1Z2WA 4TUGA 3PSOA 4H1YP 1OI8A 4H1SA 2GJUA 3K7VC 2IAEC 4DHLA 4UT3A 1S3NA 1M63A 3EGGA 3RL3A 3AV0A 1NNWA 4ORAA 2Q8UA 3QG5C 4FBWA 3LL8A 2O8AA 3E0JA 4JA7A 4O4KA 2Z72A 3QFMA 3N5UA 4LTYA 3H64A 3IB8A 3V4YA 4UT3B 4FBKA 3TGHA 3PSNA 1TCOA 1XM7A 2Z06A 3CK2A 3H61A 4ZX2A 3DSCA 1S70A 2HYPA 1WARA 2WDCA 2ZO9B 4M0VA 2XMOA 3K7WC 1S95A 1UF3A 4O24A 1V73A 2QFRA 3KBPA 1SU1A 2NXFA 2WDFA 3DW8C 3E7AA 4O5GA 5JPEA 2DXLA 4B2OA 5INBA 1IT6A 1AUIA 1U32A 3FLOA 3H69A 2P6BA 1USHA 5DNYA 5IOHA 1OIDA 3IB7A 5C1VA 1Z2XA 2ZOAA 4NZVA 1S3LA 1KBPA 4DSYA 1T71A 3C9FA 3EGHA 2ZBMA 2A22A 3ZU0A 5J28A 1G5BA 1HPUA 4I5LC 4KKZA 2IE4C 4XPNA 2NPPC 3H60A 4DT2A 3H67A 4ORCA 3ICFA 2HYOA 3H63A 1HO5A 2AHDA 1W24A 1QFCA 3AUZA 4MOYA 4V0WA 3RL4A 4ZVZA 4UT2A 4G9JA 3FGAC 5B8IA 3C5WC 1II7A 2YEQA 1T70A 3THNA 4IYPC 2QFPA 5HPEA 1UTEA 3T1IA 2KKNA 4MOVA 2DFJA 3D03A 4V0XA 4KBPA 2HY1A 5GTUA 3GVEA 4H2GA 4I5NC 4IL1A 3QFKA 2DXNA 4ORBA 2NYLC 3H62B 4TUIA 2Z1AA 4LACC 5JJTA 3DSDA 1FJMA 1HP1A 2R17A 4V0VA 1WAO1 3RQZA 4YKEA 3H68A 2JOGA 4MP0A 4O43A 2O8GA 4H2FA 4Q7FA 4J6OA 1QHWA 1MF8A 3E7BA 2IE3C 2NYMC 2WDEA 3JYFA 4WWLA 1OIEA 3QFNA 4H2BA 4UWQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FLO A; 
#chains in the Genus database with same CATH topology
 2USH A;  3H66 A;  1S3M A;  4H2I A;  4HD0 A;  4F0Z A;  2WDD A;  4JA9 A;  4LU9 A;  3RL5 A;  4FCX A;  5F3W A;  1JK7 A;  2BQ8 X;  3ZTV A;  1S8E A;  2BDX A;  3THO B;  3IVD A;  3QFO A;  1XZW A;  3IVE A;  5EQV A;  4FBQ A;  2BCD A;  5JPF A;  3HVQ A;  3P71 C;  2CV9 A;  2QJC A;  2YVT A;  4OR9 A;  1Z2W A;  4TUG A;  3PSO A;  4H1Y P;  1OI8 A;  4H1S A;  2GJU A;  3K7V C;  2IAE C;  4DHL A;  4UT3 A;  1S3N A;  1M63 A;  3EGG A;  3RL3 A;  3AV0 A;  1NNW A;  4ORA A;  2Q8U A;  3QG5 C;  4FBW A;  3LL8 A;  2O8A A;  3E0J A;  4JA7 A;  4O4K A;  2Z72 A;  3QFM A;  3N5U A;  4LTY A;  3H64 A;  3IB8 A;  3V4Y A;  4UT3 B;  4FBK A;  3TGH A;  3PSN A;  1TCO A;  1XM7 A;  2Z06 A;  3CK2 A;  3H61 A;  4ZX2 A;  3DSC A;  1S70 A;  2HYP A;  1WAR A;  2WDC A;  2ZO9 B;  4M0V A;  2XMO A;  3K7W C;  1S95 A;  1UF3 A;  4O24 A;  1V73 A;  2QFR A;  3KBP A;  1SU1 A;  2NXF A;  2WDF A;  3DW8 C;  3E7A A;  4O5G A;  5JPE A;  2DXL A;  4B2O A;  5INB A;  1IT6 A;  1AUI A;  1U32 A;  3FLO A;  3H69 A;  2P6B A;  1USH A;  5DNY A;  5IOH A;  1OID A;  3IB7 A;  5C1V A;  1Z2X A;  2ZOA A;  4NZV A;  1S3L A;  1KBP A;  4DSY A;  1T71 A;  3C9F A;  3EGH A;  2ZBM A;  2A22 A;  3ZU0 A;  5J28 A;  1G5B A;  1HPU A;  4I5L C;  4KKZ A;  2IE4 C;  4XPN A;  2NPP C;  3H60 A;  4DT2 A;  3H67 A;  4ORC A;  3ICF A;  2HYO A;  3H63 A;  1HO5 A;  2AHD A;  1W24 A;  1QFC A;  3AUZ A;  4MOY A;  4V0W A;  3RL4 A;  4ZVZ A;  4UT2 A;  4G9J A;  3FGA C;  5B8I A;  3C5W C;  1II7 A;  2YEQ A;  1T70 A;  3THN A;  4IYP C;  2QFP A;  5HPE A;  1UTE A;  3T1I A;  2KKN A;  4MOV A;  2DFJ A;  3D03 A;  4V0X A;  4KBP A;  2HY1 A;  5GTU A;  3GVE A;  4H2G A;  4I5N C;  4IL1 A;  3QFK A;  2DXN A;  4ORB A;  2NYL C;  3H62 B;  4TUI A;  2Z1A A;  4LAC C;  5JJT A;  3DSD A;  1FJM A;  1HP1 A;  2R17 A;  4V0V A;  1WAO 1;  3RQZ A;  4YKE A;  3H68 A;  2JOG A;  4MP0 A;  4O43 A;  2O8G A;  4H2F A;  4Q7F A;  4J6O A;  1QHW A;  1MF8 A;  3E7B A;  2IE3 C;  2NYM C;  2WDE A;  3JYF A;  4WWL A;  1OIE A;  3QFN A;  4H2B A;  4UWQ A; 
#chains in the Genus database with same CATH homology
 2USH A;  3H66 A;  1S3M A;  4H2I A;  4HD0 A;  4F0Z A;  2WDD A;  4JA9 A;  4LU9 A;  3RL5 A;  4FCX A;  5F3W A;  1JK7 A;  2BQ8 X;  3ZTV A;  1S8E A;  2BDX A;  3THO B;  3IVD A;  3QFO A;  1XZW A;  3IVE A;  5EQV A;  4FBQ A;  2BCD A;  5JPF A;  3HVQ A;  3P71 C;  2CV9 A;  2QJC A;  2YVT A;  4OR9 A;  1Z2W A;  4TUG A;  3PSO A;  4H1Y P;  1OI8 A;  4H1S A;  2GJU A;  3K7V C;  2IAE C;  4DHL A;  4UT3 A;  1S3N A;  1M63 A;  3EGG A;  3RL3 A;  3AV0 A;  1NNW A;  4ORA A;  2Q8U A;  3QG5 C;  4FBW A;  3LL8 A;  2O8A A;  3E0J A;  4JA7 A;  4O4K A;  2Z72 A;  3QFM A;  3N5U A;  4LTY A;  3H64 A;  3IB8 A;  3V4Y A;  4UT3 B;  4FBK A;  3TGH A;  3PSN A;  1TCO A;  1XM7 A;  2Z06 A;  3CK2 A;  3H61 A;  4ZX2 A;  3DSC A;  1S70 A;  2HYP A;  1WAR A;  2WDC A;  2ZO9 B;  4M0V A;  2XMO A;  3K7W C;  1S95 A;  1UF3 A;  4O24 A;  1V73 A;  2QFR A;  3KBP A;  1SU1 A;  2NXF A;  2WDF A;  3DW8 C;  3E7A A;  4O5G A;  5JPE A;  2DXL A;  4B2O A;  5INB A;  1IT6 A;  1AUI A;  1U32 A;  3FLO A;  3H69 A;  2P6B A;  1USH A;  5DNY A;  5IOH A;  1OID A;  3IB7 A;  5C1V A;  1Z2X A;  2ZOA A;  4NZV A;  1S3L A;  1KBP A;  4DSY A;  1T71 A;  3C9F A;  3EGH A;  2ZBM A;  2A22 A;  3ZU0 A;  5J28 A;  1G5B A;  1HPU A;  4I5L C;  4KKZ A;  2IE4 C;  4XPN A;  2NPP C;  3H60 A;  4DT2 A;  3H67 A;  4ORC A;  3ICF A;  2HYO A;  3H63 A;  1HO5 A;  2AHD A;  1W24 A;  1QFC A;  3AUZ A;  4MOY A;  4V0W A;  3RL4 A;  4ZVZ A;  4UT2 A;  4G9J A;  3FGA C;  5B8I A;  3C5W C;  1II7 A;  2YEQ A;  1T70 A;  3THN A;  4IYP C;  2QFP A;  5HPE A;  1UTE A;  3T1I A;  2KKN A;  4MOV A;  2DFJ A;  3D03 A;  4V0X A;  4KBP A;  2HY1 A;  5GTU A;  3GVE A;  4H2G A;  4I5N C;  4IL1 A;  3QFK A;  2DXN A;  4ORB A;  2NYL C;  3H62 B;  4TUI A;  2Z1A A;  4LAC C;  5JJT A;  3DSD A;  1FJM A;  1HP1 A;  2R17 A;  4V0V A;  1WAO 1;  3RQZ A;  4YKE A;  3H68 A;  2JOG A;  4MP0 A;  4O43 A;  2O8G A;  4H2F A;  4Q7F A;  4J6O A;  1QHW A;  1MF8 A;  3E7B A;  2IE3 C;  2NYM C;  2WDE A;  3JYF A;  4WWL A;  1OIE A;  3QFN A;  4H2B A;  4UWQ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...