1WARA

Recombinant human purple acid phosphatase expressed in pichia pastoris
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
310
structure length
310
Chain Sequence
EAEAEFATPALRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQILGADFILSLGDNFYFTGVQDINDKRFQETFEDVFSDRSLRKVPWYVLAGNHDHLGNVSAQIAYSKISKRWNFPSPFYRLHFKIPQTNVSVAIFMLDTVTLCGNSDDFLSQQPERPRDVKLARTQLSWLKKQLAAAREDYVLVAGHYPVWSIAEHGPTHCLVKQLRPLLATYGVTAYLCGHDHNLQYLQDENGVGYVLSGAGNFMDPSKRHQRKVPNGYLRFHYGTEDSLGGFAYVEISSKEMTVTYIEASGKSLFKTRLPRRARP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords HUMAN PURPLE ACID PHOSPHATASE
publication title Crystal Structures of Recombinant Human Purple Acid Phosphatase with and without an Inhibitory Conformation of the Repression Loop.
pubmed doi rcsb
source organism Homo sapiens
total genus 109
structure length 310
sequence length 310
ec nomenclature ec 3.1.3.2: Acid phosphatase.
pdb deposition date 2004-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 1warA00
3C5WC 2Q8UA 2P6BA 4O43A 3IVEA 2HYPA 2USHA 2A22A 1UF3A 5F3WA 4DT2A 5DNYA 4KBPA 3THOB 3V4YA 2BQ8X 4DHLA 3H61A 3HVQA 4H2IA 3THNA 3K7WC 2HYOA 3QFKA 1M63A 3DSCA 1UTEA 3H64A 4FBKA 3H63A 2QFRA 4J6OA 5JJTA 4FBWA 4H2GA 1Z2WA 3CK2A 4G9JA 5B8IA 3EGHA 3AUZA 2JOGA 1W24A 2Z72A 1OIEA 4I5LC 4ZVZA 1IT6A 1S3NA 2IE4C 3DSDA 4UWQA 2DFJA 1SU1A 2CV9A 1KBPA 3PSNA 4H1SA 1S3LA 4UT3B 4WWLA 1USHA 1Z2XA 2IAEC 3H66A 1QHWA 4I5NC 4O24A 1OI8A 1MF8A 5JPEA 3ZU0A 4TUIA 4FBQA 4DSYA 4YKEA 3QFNA 4FCXA 4TUGA 3RL3A 3QG5C 2YVTA 3EGGA 4LU9A 4F0ZA 1OIDA 3PSOA 1XM7A 4V0VA 3RL4A 2NXFA 4KKZA 5INBA 4ZX2A 3H62B 3C9FA 1NNWA 3LL8A 1AUIA 4H1YP 1WAO1 5IOHA 2NYLC 3T1IA 5GTUA 2NYMC 2ZBMA 3GVEA 1T71A 1V73A 2KKNA 3K7VC 4IL1A 2O8AA 3H68A 4UT2A 1S3MA 1HP1A 2WDCA 1S8EA 2XMOA 3H60A 3IB8A 2BDXA 2Z06A 4MP0A 3ZTVA 2WDDA 3P71C 2HY1A 1G5BA 1U32A 4MOYA 4V0WA 4XPNA 1HO5A 1QFCA 1XZWA 2NPPC 4O5GA 2R17A 1TCOA 2AHDA 4HD0A 1JK7A 4JA9A 4MOVA 3TGHA 4H2BA 2WDEA 4LTYA 3N5UA 1S70A 4M0VA 1II7A 3E7AA 3RL5A 4ORCA 4B2OA 4ORBA 1WARA 2BCDA 3IVDA 3E7BA 1HPUA 4OR9A 4ORAA 3RQZA 2Z1AA 3QFMA 5EQVA 2QFPA 2WDFA 3FGAC 3ICFA 5JPFA 2QJCA 4UT3A 3QFOA 1S95A 4NZVA 4LACC 2IE3C 1T70A 3KBPA 4JA7A 4O4KA 3IB7A 5HPEA 3DW8C 1FJMA 3JYFA 2GJUA 4V0XA 4H2FA 2O8GA 5C1VA 3H67A 4Q7FA 5J28A 4IYPC 3H69A 3AV0A
chains in the Genus database with same CATH superfamily
3C5WC 2Q8UA 2P6BA 4O43A 3IVEA 2HYPA 2USHA 2A22A 1UF3A 5F3WA 4DT2A 5DNYA 4KBPA 3THOB 3V4YA 2BQ8X 4DHLA 3H61A 3HVQA 4H2IA 3THNA 3K7WC 2HYOA 3QFKA 1M63A 3DSCA 1UTEA 3H64A 4FBKA 3H63A 2QFRA 4J6OA 5JJTA 3FLOA 4FBWA 4H2GA 1Z2WA 3CK2A 4G9JA 5B8IA 3EGHA 3D03A 3AUZA 2JOGA 1W24A 2Z72A 1OIEA 4I5LC 4ZVZA 1IT6A 1S3NA 2IE4C 3DSDA 4UWQA 2DFJA 2ZOAA 1SU1A 2CV9A 1KBPA 3PSNA 4H1SA 1S3LA 4UT3B 4WWLA 1USHA 1Z2XA 2IAEC 3H66A 1QHWA 4I5NC 4O24A 1OI8A 1MF8A 2DXLA 2YEQA 5JPEA 3ZU0A 4TUIA 4FBQA 4DSYA 2DXNA 4YKEA 3QFNA 4FCXA 4TUGA 3RL3A 3QG5C 2YVTA 3EGGA 4LU9A 4F0ZA 1OIDA 3PSOA 1XM7A 4V0VA 3RL4A 2NXFA 4KKZA 5INBA 4ZX2A 3H62B 2ZO9B 3C9FA 1NNWA 3LL8A 1AUIA 4H1YP 1WAO1 5IOHA 2NYLC 3T1IA 5GTUA 2NYMC 2ZBMA 3GVEA 1T71A 1V73A 2KKNA 3K7VC 4IL1A 2O8AA 3H68A 4UT2A 1S3MA 1HP1A 2WDCA 1S8EA 2XMOA 3H60A 3IB8A 2BDXA 2Z06A 4MP0A 3ZTVA 2WDDA 3P71C 2HY1A 1G5BA 1U32A 4MOYA 4V0WA 4XPNA 1HO5A 1QFCA 1XZWA 2NPPC 4O5GA 2R17A 1TCOA 2AHDA 4HD0A 1JK7A 4JA9A 3E0JA 4MOVA 3TGHA 4H2BA 2WDEA 4LTYA 3N5UA 1S70A 4M0VA 1II7A 3E7AA 3RL5A 4ORCA 4B2OA 4ORBA 1WARA 2BCDA 3IVDA 3E7BA 1HPUA 4OR9A 4ORAA 3RQZA 2Z1AA 3QFMA 5EQVA 2QFPA 2WDFA 3FGAC 3ICFA 5JPFA 2QJCA 4UT3A 3QFOA 1S95A 4NZVA 4LACC 2IE3C 1T70A 3KBPA 4JA7A 4O4KA 3IB7A 5HPEA 3DW8C 1FJMA 3JYFA 2GJUA 4V0XA 4H2FA 2O8GA 5C1VA 3H67A 4Q7FA 5J28A 4IYPC 3H69A 3AV0A
chains in the Genus database with same CATH topology
3C5WC 2Q8UA 2P6BA 4O43A 3IVEA 2HYPA 2USHA 2A22A 1UF3A 5F3WA 4DT2A 5DNYA 4KBPA 3THOB 3V4YA 2BQ8X 4DHLA 3H61A 3HVQA 4H2IA 3THNA 3K7WC 2HYOA 3QFKA 1M63A 3DSCA 1UTEA 3H64A 4FBKA 3H63A 2QFRA 4J6OA 5JJTA 3FLOA 4FBWA 4H2GA 1Z2WA 3CK2A 4G9JA 5B8IA 3EGHA 3D03A 3AUZA 2JOGA 1W24A 2Z72A 1OIEA 4I5LC 4ZVZA 1IT6A 1S3NA 2IE4C 3DSDA 4UWQA 2DFJA 2ZOAA 1SU1A 2CV9A 1KBPA 3PSNA 4H1SA 1S3LA 4UT3B 4WWLA 1USHA 1Z2XA 2IAEC 3H66A 1QHWA 4I5NC 4O24A 1OI8A 1MF8A 2DXLA 2YEQA 5JPEA 3ZU0A 4TUIA 4FBQA 4DSYA 2DXNA 4YKEA 3QFNA 4FCXA 4TUGA 3RL3A 3QG5C 2YVTA 3EGGA 4LU9A 4F0ZA 1OIDA 3PSOA 1XM7A 4V0VA 3RL4A 2NXFA 4KKZA 5INBA 4ZX2A 3H62B 2ZO9B 3C9FA 1NNWA 3LL8A 1AUIA 4H1YP 1WAO1 5IOHA 2NYLC 3T1IA 5GTUA 2NYMC 2ZBMA 3GVEA 1T71A 1V73A 2KKNA 3K7VC 4IL1A 2O8AA 3H68A 4UT2A 1S3MA 1HP1A 2WDCA 1S8EA 2XMOA 3H60A 3IB8A 2BDXA 2Z06A 4MP0A 3ZTVA 2WDDA 3P71C 2HY1A 1G5BA 1U32A 4MOYA 4V0WA 4XPNA 1HO5A 1QFCA 1XZWA 2NPPC 4O5GA 2R17A 1TCOA 2AHDA 4HD0A 1JK7A 4JA9A 3E0JA 4MOVA 3TGHA 4H2BA 2WDEA 4LTYA 3N5UA 1S70A 4M0VA 1II7A 3E7AA 3RL5A 4ORCA 4B2OA 4ORBA 1WARA 2BCDA 3IVDA 3E7BA 1HPUA 4OR9A 4ORAA 3RQZA 2Z1AA 3QFMA 5EQVA 2QFPA 2WDFA 3FGAC 3ICFA 5JPFA 2QJCA 4UT3A 3QFOA 1S95A 4NZVA 4LACC 2IE3C 1T70A 3KBPA 4JA7A 4O4KA 3IB7A 5HPEA 3DW8C 1FJMA 3JYFA 2GJUA 4V0XA 4H2FA 2O8GA 5C1VA 3H67A 4Q7FA 5J28A 4IYPC 3H69A 3AV0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C5W C;  2Q8U A;  2P6B A;  4O43 A;  3IVE A;  2HYP A;  2USH A;  2A22 A;  1UF3 A;  5F3W A;  4DT2 A;  5DNY A;  4KBP A;  3THO B;  3V4Y A;  2BQ8 X;  4DHL A;  3H61 A;  3HVQ A;  4H2I A;  3THN A;  3K7W C;  2HYO A;  3QFK A;  1M63 A;  3DSC A;  1UTE A;  3H64 A;  4FBK A;  3H63 A;  2QFR A;  4J6O A;  5JJT A;  4FBW A;  4H2G A;  1Z2W A;  3CK2 A;  4G9J A;  5B8I A;  3EGH A;  3AUZ A;  2JOG A;  1W24 A;  2Z72 A;  1OIE A;  4I5L C;  4ZVZ A;  1IT6 A;  1S3N A;  2IE4 C;  3DSD A;  4UWQ A;  2DFJ A;  1SU1 A;  2CV9 A;  1KBP A;  3PSN A;  4H1S A;  1S3L A;  4UT3 B;  4WWL A;  1USH A;  1Z2X A;  2IAE C;  3H66 A;  1QHW A;  4I5N C;  4O24 A;  1OI8 A;  1MF8 A;  5JPE A;  3ZU0 A;  4TUI A;  4FBQ A;  4DSY A;  4YKE A;  3QFN A;  4FCX A;  4TUG A;  3RL3 A;  3QG5 C;  2YVT A;  3EGG A;  4LU9 A;  4F0Z A;  1OID A;  3PSO A;  1XM7 A;  4V0V A;  3RL4 A;  2NXF A;  4KKZ A;  5INB A;  4ZX2 A;  3H62 B;  3C9F A;  1NNW A;  3LL8 A;  1AUI A;  4H1Y P;  1WAO 1;  5IOH A;  2NYL C;  3T1I A;  5GTU A;  2NYM C;  2ZBM A;  3GVE A;  1T71 A;  1V73 A;  2KKN A;  3K7V C;  4IL1 A;  2O8A A;  3H68 A;  4UT2 A;  1S3M A;  1HP1 A;  2WDC A;  1S8E A;  2XMO A;  3H60 A;  3IB8 A;  2BDX A;  2Z06 A;  4MP0 A;  3ZTV A;  2WDD A;  3P71 C;  2HY1 A;  1G5B A;  1U32 A;  4MOY A;  4V0W A;  4XPN A;  1HO5 A;  1QFC A;  1XZW A;  2NPP C;  4O5G A;  2R17 A;  1TCO A;  2AHD A;  4HD0 A;  1JK7 A;  4JA9 A;  4MOV A;  3TGH A;  4H2B A;  2WDE A;  4LTY A;  3N5U A;  1S70 A;  4M0V A;  1II7 A;  3E7A A;  3RL5 A;  4ORC A;  4B2O A;  4ORB A;  1WAR A;  2BCD A;  3IVD A;  3E7B A;  1HPU A;  4OR9 A;  4ORA A;  3RQZ A;  2Z1A A;  3QFM A;  5EQV A;  2QFP A;  2WDF A;  3FGA C;  3ICF A;  5JPF A;  2QJC A;  4UT3 A;  3QFO A;  1S95 A;  4NZV A;  4LAC C;  2IE3 C;  1T70 A;  3KBP A;  4JA7 A;  4O4K A;  3IB7 A;  5HPE A;  3DW8 C;  1FJM A;  3JYF A;  2GJU A;  4V0X A;  4H2F A;  2O8G A;  5C1V A;  3H67 A;  4Q7F A;  5J28 A;  4IYP C;  3H69 A;  3AV0 A; 
#chains in the Genus database with same CATH topology
 3C5W C;  2Q8U A;  2P6B A;  4O43 A;  3IVE A;  2HYP A;  2USH A;  2A22 A;  1UF3 A;  5F3W A;  4DT2 A;  5DNY A;  4KBP A;  3THO B;  3V4Y A;  2BQ8 X;  4DHL A;  3H61 A;  3HVQ A;  4H2I A;  3THN A;  3K7W C;  2HYO A;  3QFK A;  1M63 A;  3DSC A;  1UTE A;  3H64 A;  4FBK A;  3H63 A;  2QFR A;  4J6O A;  5JJT A;  3FLO A;  4FBW A;  4H2G A;  1Z2W A;  3CK2 A;  4G9J A;  5B8I A;  3EGH A;  3D03 A;  3AUZ A;  2JOG A;  1W24 A;  2Z72 A;  1OIE A;  4I5L C;  4ZVZ A;  1IT6 A;  1S3N A;  2IE4 C;  3DSD A;  4UWQ A;  2DFJ A;  2ZOA A;  1SU1 A;  2CV9 A;  1KBP A;  3PSN A;  4H1S A;  1S3L A;  4UT3 B;  4WWL A;  1USH A;  1Z2X A;  2IAE C;  3H66 A;  1QHW A;  4I5N C;  4O24 A;  1OI8 A;  1MF8 A;  2DXL A;  2YEQ A;  5JPE A;  3ZU0 A;  4TUI A;  4FBQ A;  4DSY A;  2DXN A;  4YKE A;  3QFN A;  4FCX A;  4TUG A;  3RL3 A;  3QG5 C;  2YVT A;  3EGG A;  4LU9 A;  4F0Z A;  1OID A;  3PSO A;  1XM7 A;  4V0V A;  3RL4 A;  2NXF A;  4KKZ A;  5INB A;  4ZX2 A;  3H62 B;  2ZO9 B;  3C9F A;  1NNW A;  3LL8 A;  1AUI A;  4H1Y P;  1WAO 1;  5IOH A;  2NYL C;  3T1I A;  5GTU A;  2NYM C;  2ZBM A;  3GVE A;  1T71 A;  1V73 A;  2KKN A;  3K7V C;  4IL1 A;  2O8A A;  3H68 A;  4UT2 A;  1S3M A;  1HP1 A;  2WDC A;  1S8E A;  2XMO A;  3H60 A;  3IB8 A;  2BDX A;  2Z06 A;  4MP0 A;  3ZTV A;  2WDD A;  3P71 C;  2HY1 A;  1G5B A;  1U32 A;  4MOY A;  4V0W A;  4XPN A;  1HO5 A;  1QFC A;  1XZW A;  2NPP C;  4O5G A;  2R17 A;  1TCO A;  2AHD A;  4HD0 A;  1JK7 A;  4JA9 A;  3E0J A;  4MOV A;  3TGH A;  4H2B A;  2WDE A;  4LTY A;  3N5U A;  1S70 A;  4M0V A;  1II7 A;  3E7A A;  3RL5 A;  4ORC A;  4B2O A;  4ORB A;  1WAR A;  2BCD A;  3IVD A;  3E7B A;  1HPU A;  4OR9 A;  4ORA A;  3RQZ A;  2Z1A A;  3QFM A;  5EQV A;  2QFP A;  2WDF A;  3FGA C;  3ICF A;  5JPF A;  2QJC A;  4UT3 A;  3QFO A;  1S95 A;  4NZV A;  4LAC C;  2IE3 C;  1T70 A;  3KBP A;  4JA7 A;  4O4K A;  3IB7 A;  5HPE A;  3DW8 C;  1FJM A;  3JYF A;  2GJU A;  4V0X A;  4H2F A;  2O8G A;  5C1V A;  3H67 A;  4Q7F A;  5J28 A;  4IYP C;  3H69 A;  3AV0 A; 
#chains in the Genus database with same CATH homology
 3C5W C;  2Q8U A;  2P6B A;  4O43 A;  3IVE A;  2HYP A;  2USH A;  2A22 A;  1UF3 A;  5F3W A;  4DT2 A;  5DNY A;  4KBP A;  3THO B;  3V4Y A;  2BQ8 X;  4DHL A;  3H61 A;  3HVQ A;  4H2I A;  3THN A;  3K7W C;  2HYO A;  3QFK A;  1M63 A;  3DSC A;  1UTE A;  3H64 A;  4FBK A;  3H63 A;  2QFR A;  4J6O A;  5JJT A;  3FLO A;  4FBW A;  4H2G A;  1Z2W A;  3CK2 A;  4G9J A;  5B8I A;  3EGH A;  3D03 A;  3AUZ A;  2JOG A;  1W24 A;  2Z72 A;  1OIE A;  4I5L C;  4ZVZ A;  1IT6 A;  1S3N A;  2IE4 C;  3DSD A;  4UWQ A;  2DFJ A;  2ZOA A;  1SU1 A;  2CV9 A;  1KBP A;  3PSN A;  4H1S A;  1S3L A;  4UT3 B;  4WWL A;  1USH A;  1Z2X A;  2IAE C;  3H66 A;  1QHW A;  4I5N C;  4O24 A;  1OI8 A;  1MF8 A;  2DXL A;  2YEQ A;  5JPE A;  3ZU0 A;  4TUI A;  4FBQ A;  4DSY A;  2DXN A;  4YKE A;  3QFN A;  4FCX A;  4TUG A;  3RL3 A;  3QG5 C;  2YVT A;  3EGG A;  4LU9 A;  4F0Z A;  1OID A;  3PSO A;  1XM7 A;  4V0V A;  3RL4 A;  2NXF A;  4KKZ A;  5INB A;  4ZX2 A;  3H62 B;  2ZO9 B;  3C9F A;  1NNW A;  3LL8 A;  1AUI A;  4H1Y P;  1WAO 1;  5IOH A;  2NYL C;  3T1I A;  5GTU A;  2NYM C;  2ZBM A;  3GVE A;  1T71 A;  1V73 A;  2KKN A;  3K7V C;  4IL1 A;  2O8A A;  3H68 A;  4UT2 A;  1S3M A;  1HP1 A;  2WDC A;  1S8E A;  2XMO A;  3H60 A;  3IB8 A;  2BDX A;  2Z06 A;  4MP0 A;  3ZTV A;  2WDD A;  3P71 C;  2HY1 A;  1G5B A;  1U32 A;  4MOY A;  4V0W A;  4XPN A;  1HO5 A;  1QFC A;  1XZW A;  2NPP C;  4O5G A;  2R17 A;  1TCO A;  2AHD A;  4HD0 A;  1JK7 A;  4JA9 A;  3E0J A;  4MOV A;  3TGH A;  4H2B A;  2WDE A;  4LTY A;  3N5U A;  1S70 A;  4M0V A;  1II7 A;  3E7A A;  3RL5 A;  4ORC A;  4B2O A;  4ORB A;  1WAR A;  2BCD A;  3IVD A;  3E7B A;  1HPU A;  4OR9 A;  4ORA A;  3RQZ A;  2Z1A A;  3QFM A;  5EQV A;  2QFP A;  2WDF A;  3FGA C;  3ICF A;  5JPF A;  2QJC A;  4UT3 A;  3QFO A;  1S95 A;  4NZV A;  4LAC C;  2IE3 C;  1T70 A;  3KBP A;  4JA7 A;  4O4K A;  3IB7 A;  5HPE A;  3DW8 C;  1FJM A;  3JYF A;  2GJU A;  4V0X A;  4H2F A;  2O8G A;  5C1V A;  3H67 A;  4Q7F A;  5J28 A;  4IYP C;  3H69 A;  3AV0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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