1WARA

Recombinant human purple acid phosphatase expressed in pichia pastoris
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
310
structure length
310
Chain Sequence
EAEAEFATPALRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQILGADFILSLGDNFYFTGVQDINDKRFQETFEDVFSDRSLRKVPWYVLAGNHDHLGNVSAQIAYSKISKRWNFPSPFYRLHFKIPQTNVSVAIFMLDTVTLCGNSDDFLSQQPERPRDVKLARTQLSWLKKQLAAAREDYVLVAGHYPVWSIAEHGPTHCLVKQLRPLLATYGVTAYLCGHDHNLQYLQDENGVGYVLSGAGNFMDPSKRHQRKVPNGYLRFHYGTEDSLGGFAYVEISSKEMTVTYIEASGKSLFKTRLPRRARP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Recombinant Human Purple Acid Phosphatase with and without an Inhibitory Conformation of the Repression Loop.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
molecule keywords HUMAN PURPLE ACID PHOSPHATASE
total genus 109
structure length 310
sequence length 310
ec nomenclature ec 3.1.3.2: Acid phosphatase.
pdb deposition date 2004-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 1warA00
3DSDA 2XMOA 4DSYA 5C1VA 1W24A 4I5LC 1WARA 1U32A 2YVTA 3ZTVA 4MOVA 4O43A 5JPFA 3C9FA 1T71A 1UTEA 3DW8C 4DHLA 2HYOA 3IB7A 5IOHA 1M63A 4UT2A 4OR9A 1UF3A 3QFOA 4UT3B 2QFPA 2BQ8X 1KBPA 4ORCA 5INBA 3QG5C 4LACC 3PSNA 4JA7A 4ZVZA 1G5BA 3V4YA 4LU9A 2P6BA 4TUGA 1SU1A 4XPNA 2IAEC 2IE3C 4H1YP 2WDEA 3ICFA 3P71C 4MP0A 3K7WC 1IT6A 2NYMC 2HY1A 3H68A 4H2BA 2R17A 3RL5A 1HP1A 3FGAC 5EQVA 5F3WA 1USHA 4J6OA 3QFMA 4B2OA 4V0XA 3C5WC 2GJUA 1WAO1 3IVEA 3THOB 1Z2WA 1S3NA 2WDFA 3H61A 4IL1A 3LL8A 4FBKA 1S95A 2CV9A 2USHA 3H64A 3DSCA 2BDXA 3KBPA 4V0WA 4V0VA 4LTYA 1Z2XA 4Q7FA 5B8IA 2Q8UA 4H2IA 4ORAA 4F0ZA 3TGHA 3THNA 2NPPC 2NXFA 2NYLC 1NNWA 2ZBMA 3GVEA 4KBPA 3E7BA 3IVDA 3H69A 3QFKA 3K7VC 3EGHA 1AUIA 3N5UA 4O5GA 1OIDA 2WDCA 1T70A 2BCDA 1QFCA 1JK7A 5GTUA 4JA9A 1FJMA 2Z1AA 4MOYA 3H62B 3RL3A 4O24A 2A22A 4UT3A 1HPUA 3H60A 5JPEA 3AUZA 2IE4C 5JJTA 1V73A 1OI8A 2HYPA 3PSOA 2O8GA 2O8AA 4FBWA 1XZWA 4KKZA 1II7A 4ORBA 4O4KA 4G9JA 5DNYA 2AHDA 3JYFA 4UWQA 4FBQA 1XM7A 3RQZA 2QJCA 2QFRA 4DT2A 3CK2A 4H2GA 3T1IA 4YKEA 1MF8A 3HVQA 4FCXA 3RL4A 2Z06A 3H67A 3QFNA 4I5NC 1S3MA 1HO5A 5HPEA 3ZU0A 3E7AA 4H2FA 4ZX2A 4WWLA 2DFJA 5J28A 4M0VA 3IB8A 1S8EA 1S3LA 4HD0A 2Z72A 1TCOA 3AV0A 3EGGA 1OIEA 2JOGA 2KKNA 2WDDA 4NZVA 4TUIA 3H63A 4IYPC 1S70A 3H66A 4H1SA 1QHWA
chains in the Genus database with same CATH superfamily
3DSDA 2XMOA 4DSYA 5C1VA 1W24A 4I5LC 1WARA 1U32A 2YVTA 3ZTVA 4MOVA 4O43A 5JPFA 3C9FA 1T71A 1UTEA 3DW8C 4DHLA 2HYOA 3IB7A 5IOHA 1M63A 4UT2A 4OR9A 1UF3A 3QFOA 4UT3B 2QFPA 2BQ8X 1KBPA 4ORCA 5INBA 3QG5C 4LACC 3PSNA 4JA7A 4ZVZA 1G5BA 3V4YA 4LU9A 2P6BA 4TUGA 1SU1A 4XPNA 2IAEC 2IE3C 4H1YP 2WDEA 3ICFA 3P71C 4MP0A 3K7WC 1IT6A 2NYMC 2HY1A 3H68A 4H2BA 2R17A 3RL5A 1HP1A 3FGAC 5EQVA 5F3WA 1USHA 4J6OA 3QFMA 4B2OA 4V0XA 3C5WC 2GJUA 1WAO1 3IVEA 3THOB 1Z2WA 1S3NA 2WDFA 3H61A 4IL1A 3LL8A 4FBKA 1S95A 2CV9A 2USHA 3H64A 3DSCA 2BDXA 3KBPA 4V0WA 4V0VA 4LTYA 1Z2XA 2DXNA 4Q7FA 2Q8UA 4H2IA 3E0JA 4ORAA 4F0ZA 5B8IA 3TGHA 3THNA 2NPPC 2NXFA 2NYLC 1NNWA 2ZBMA 3GVEA 4KBPA 3E7BA 3IVDA 3H69A 3QFKA 3K7VC 3EGHA 1AUIA 3FLOA 3N5UA 1OIDA 4O5GA 2WDCA 1T70A 2BCDA 1QFCA 1JK7A 5GTUA 4JA9A 1FJMA 2Z1AA 4MOYA 3H62B 2YEQA 3RL3A 4O24A 2A22A 4UT3A 1HPUA 3H60A 5JPEA 3AUZA 2IE4C 5JJTA 1V73A 1OI8A 2HYPA 3PSOA 2O8GA 2O8AA 4FBWA 1XZWA 4KKZA 1II7A 4ORBA 4O4KA 4G9JA 5DNYA 2AHDA 3JYFA 4UWQA 4FBQA 1XM7A 3RQZA 2QJCA 2QFRA 4DT2A 3CK2A 4H2GA 3T1IA 4YKEA 1MF8A 3HVQA 4FCXA 3RL4A 2Z06A 3H67A 3QFNA 4I5NC 1S3MA 1HO5A 5HPEA 3ZU0A 2DXLA 3E7AA 4H2FA 4ZX2A 4WWLA 2DFJA 2ZO9B 5J28A 4M0VA 3IB8A 2ZOAA 1S8EA 1S3LA 4HD0A 2Z72A 1TCOA 3D03A 3AV0A 3EGGA 1OIEA 2JOGA 2KKNA 2WDDA 4NZVA 4TUIA 3H63A 4IYPC 1S70A 3H66A 4H1SA 1QHWA
chains in the Genus database with same CATH topology
3DSDA 2XMOA 4DSYA 5C1VA 1W24A 4I5LC 1WARA 1U32A 2YVTA 3ZTVA 4MOVA 4O43A 5JPFA 3C9FA 1T71A 1UTEA 3DW8C 4DHLA 2HYOA 3IB7A 5IOHA 1M63A 4UT2A 4OR9A 1UF3A 3QFOA 4UT3B 2QFPA 2BQ8X 1KBPA 4ORCA 5INBA 3QG5C 4LACC 3PSNA 4JA7A 4ZVZA 1G5BA 3V4YA 4LU9A 2P6BA 4TUGA 1SU1A 4XPNA 2IAEC 2IE3C 4H1YP 2WDEA 3ICFA 3P71C 4MP0A 3K7WC 1IT6A 2NYMC 2HY1A 3H68A 4H2BA 2R17A 3RL5A 1HP1A 3FGAC 5EQVA 5F3WA 1USHA 4J6OA 3QFMA 4B2OA 4V0XA 3C5WC 2GJUA 1WAO1 3IVEA 3THOB 1Z2WA 1S3NA 2WDFA 3H61A 4IL1A 3LL8A 4FBKA 1S95A 2CV9A 2USHA 3H64A 3DSCA 2BDXA 3KBPA 4V0WA 4V0VA 4LTYA 1Z2XA 2DXNA 4Q7FA 2Q8UA 4H2IA 3E0JA 4ORAA 4F0ZA 5B8IA 3TGHA 3THNA 2NPPC 2NXFA 2NYLC 1NNWA 2ZBMA 3GVEA 4KBPA 3E7BA 3IVDA 3H69A 3QFKA 3K7VC 3EGHA 1AUIA 3FLOA 3N5UA 1OIDA 4O5GA 2WDCA 1T70A 2BCDA 1QFCA 1JK7A 5GTUA 4JA9A 1FJMA 2Z1AA 4MOYA 3H62B 2YEQA 3RL3A 4O24A 2A22A 4UT3A 1HPUA 3H60A 5JPEA 3AUZA 2IE4C 5JJTA 1V73A 1OI8A 2HYPA 3PSOA 2O8GA 2O8AA 4FBWA 1XZWA 4KKZA 1II7A 4ORBA 4O4KA 4G9JA 5DNYA 2AHDA 3JYFA 4UWQA 4FBQA 1XM7A 3RQZA 2QJCA 2QFRA 4DT2A 3CK2A 4H2GA 3T1IA 4YKEA 1MF8A 3HVQA 4FCXA 3RL4A 2Z06A 3H67A 3QFNA 4I5NC 1S3MA 1HO5A 5HPEA 3ZU0A 2DXLA 3E7AA 4H2FA 4ZX2A 4WWLA 2DFJA 2ZO9B 5J28A 4M0VA 3IB8A 2ZOAA 1S8EA 1S3LA 4HD0A 2Z72A 1TCOA 3D03A 3AV0A 3EGGA 1OIEA 2JOGA 2KKNA 2WDDA 4NZVA 4TUIA 3H63A 4IYPC 1S70A 3H66A 4H1SA 1QHWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DSD A;  2XMO A;  4DSY A;  5C1V A;  1W24 A;  4I5L C;  1WAR A;  1U32 A;  2YVT A;  3ZTV A;  4MOV A;  4O43 A;  5JPF A;  3C9F A;  1T71 A;  1UTE A;  3DW8 C;  4DHL A;  2HYO A;  3IB7 A;  5IOH A;  1M63 A;  4UT2 A;  4OR9 A;  1UF3 A;  3QFO A;  4UT3 B;  2QFP A;  2BQ8 X;  1KBP A;  4ORC A;  5INB A;  3QG5 C;  4LAC C;  3PSN A;  4JA7 A;  4ZVZ A;  1G5B A;  3V4Y A;  4LU9 A;  2P6B A;  4TUG A;  1SU1 A;  4XPN A;  2IAE C;  2IE3 C;  4H1Y P;  2WDE A;  3ICF A;  3P71 C;  4MP0 A;  3K7W C;  1IT6 A;  2NYM C;  2HY1 A;  3H68 A;  4H2B A;  2R17 A;  3RL5 A;  1HP1 A;  3FGA C;  5EQV A;  5F3W A;  1USH A;  4J6O A;  3QFM A;  4B2O A;  4V0X A;  3C5W C;  2GJU A;  1WAO 1;  3IVE A;  3THO B;  1Z2W A;  1S3N A;  2WDF A;  3H61 A;  4IL1 A;  3LL8 A;  4FBK A;  1S95 A;  2CV9 A;  2USH A;  3H64 A;  3DSC A;  2BDX A;  3KBP A;  4V0W A;  4V0V A;  4LTY A;  1Z2X A;  4Q7F A;  5B8I A;  2Q8U A;  4H2I A;  4ORA A;  4F0Z A;  3TGH A;  3THN A;  2NPP C;  2NXF A;  2NYL C;  1NNW A;  2ZBM A;  3GVE A;  4KBP A;  3E7B A;  3IVD A;  3H69 A;  3QFK A;  3K7V C;  3EGH A;  1AUI A;  3N5U A;  4O5G A;  1OID A;  2WDC A;  1T70 A;  2BCD A;  1QFC A;  1JK7 A;  5GTU A;  4JA9 A;  1FJM A;  2Z1A A;  4MOY A;  3H62 B;  3RL3 A;  4O24 A;  2A22 A;  4UT3 A;  1HPU A;  3H60 A;  5JPE A;  3AUZ A;  2IE4 C;  5JJT A;  1V73 A;  1OI8 A;  2HYP A;  3PSO A;  2O8G A;  2O8A A;  4FBW A;  1XZW A;  4KKZ A;  1II7 A;  4ORB A;  4O4K A;  4G9J A;  5DNY A;  2AHD A;  3JYF A;  4UWQ A;  4FBQ A;  1XM7 A;  3RQZ A;  2QJC A;  2QFR A;  4DT2 A;  3CK2 A;  4H2G A;  3T1I A;  4YKE A;  1MF8 A;  3HVQ A;  4FCX A;  3RL4 A;  2Z06 A;  3H67 A;  3QFN A;  4I5N C;  1S3M A;  1HO5 A;  5HPE A;  3ZU0 A;  3E7A A;  4H2F A;  4ZX2 A;  4WWL A;  2DFJ A;  5J28 A;  4M0V A;  3IB8 A;  1S8E A;  1S3L A;  4HD0 A;  2Z72 A;  1TCO A;  3AV0 A;  3EGG A;  1OIE A;  2JOG A;  2KKN A;  2WDD A;  4NZV A;  4TUI A;  3H63 A;  4IYP C;  1S70 A;  3H66 A;  4H1S A;  1QHW A; 
#chains in the Genus database with same CATH topology
 3DSD A;  2XMO A;  4DSY A;  5C1V A;  1W24 A;  4I5L C;  1WAR A;  1U32 A;  2YVT A;  3ZTV A;  4MOV A;  4O43 A;  5JPF A;  3C9F A;  1T71 A;  1UTE A;  3DW8 C;  4DHL A;  2HYO A;  3IB7 A;  5IOH A;  1M63 A;  4UT2 A;  4OR9 A;  1UF3 A;  3QFO A;  4UT3 B;  2QFP A;  2BQ8 X;  1KBP A;  4ORC A;  5INB A;  3QG5 C;  4LAC C;  3PSN A;  4JA7 A;  4ZVZ A;  1G5B A;  3V4Y A;  4LU9 A;  2P6B A;  4TUG A;  1SU1 A;  4XPN A;  2IAE C;  2IE3 C;  4H1Y P;  2WDE A;  3ICF A;  3P71 C;  4MP0 A;  3K7W C;  1IT6 A;  2NYM C;  2HY1 A;  3H68 A;  4H2B A;  2R17 A;  3RL5 A;  1HP1 A;  3FGA C;  5EQV A;  5F3W A;  1USH A;  4J6O A;  3QFM A;  4B2O A;  4V0X A;  3C5W C;  2GJU A;  1WAO 1;  3IVE A;  3THO B;  1Z2W A;  1S3N A;  2WDF A;  3H61 A;  4IL1 A;  3LL8 A;  4FBK A;  1S95 A;  2CV9 A;  2USH A;  3H64 A;  3DSC A;  2BDX A;  3KBP A;  4V0W A;  4V0V A;  4LTY A;  1Z2X A;  2DXN A;  4Q7F A;  2Q8U A;  4H2I A;  3E0J A;  4ORA A;  4F0Z A;  5B8I A;  3TGH A;  3THN A;  2NPP C;  2NXF A;  2NYL C;  1NNW A;  2ZBM A;  3GVE A;  4KBP A;  3E7B A;  3IVD A;  3H69 A;  3QFK A;  3K7V C;  3EGH A;  1AUI A;  3FLO A;  3N5U A;  1OID A;  4O5G A;  2WDC A;  1T70 A;  2BCD A;  1QFC A;  1JK7 A;  5GTU A;  4JA9 A;  1FJM A;  2Z1A A;  4MOY A;  3H62 B;  2YEQ A;  3RL3 A;  4O24 A;  2A22 A;  4UT3 A;  1HPU A;  3H60 A;  5JPE A;  3AUZ A;  2IE4 C;  5JJT A;  1V73 A;  1OI8 A;  2HYP A;  3PSO A;  2O8G A;  2O8A A;  4FBW A;  1XZW A;  4KKZ A;  1II7 A;  4ORB A;  4O4K A;  4G9J A;  5DNY A;  2AHD A;  3JYF A;  4UWQ A;  4FBQ A;  1XM7 A;  3RQZ A;  2QJC A;  2QFR A;  4DT2 A;  3CK2 A;  4H2G A;  3T1I A;  4YKE A;  1MF8 A;  3HVQ A;  4FCX A;  3RL4 A;  2Z06 A;  3H67 A;  3QFN A;  4I5N C;  1S3M A;  1HO5 A;  5HPE A;  3ZU0 A;  2DXL A;  3E7A A;  4H2F A;  4ZX2 A;  4WWL A;  2DFJ A;  2ZO9 B;  5J28 A;  4M0V A;  3IB8 A;  2ZOA A;  1S8E A;  1S3L A;  4HD0 A;  2Z72 A;  1TCO A;  3D03 A;  3AV0 A;  3EGG A;  1OIE A;  2JOG A;  2KKN A;  2WDD A;  4NZV A;  4TUI A;  3H63 A;  4IYP C;  1S70 A;  3H66 A;  4H1S A;  1QHW A; 
#chains in the Genus database with same CATH homology
 3DSD A;  2XMO A;  4DSY A;  5C1V A;  1W24 A;  4I5L C;  1WAR A;  1U32 A;  2YVT A;  3ZTV A;  4MOV A;  4O43 A;  5JPF A;  3C9F A;  1T71 A;  1UTE A;  3DW8 C;  4DHL A;  2HYO A;  3IB7 A;  5IOH A;  1M63 A;  4UT2 A;  4OR9 A;  1UF3 A;  3QFO A;  4UT3 B;  2QFP A;  2BQ8 X;  1KBP A;  4ORC A;  5INB A;  3QG5 C;  4LAC C;  3PSN A;  4JA7 A;  4ZVZ A;  1G5B A;  3V4Y A;  4LU9 A;  2P6B A;  4TUG A;  1SU1 A;  4XPN A;  2IAE C;  2IE3 C;  4H1Y P;  2WDE A;  3ICF A;  3P71 C;  4MP0 A;  3K7W C;  1IT6 A;  2NYM C;  2HY1 A;  3H68 A;  4H2B A;  2R17 A;  3RL5 A;  1HP1 A;  3FGA C;  5EQV A;  5F3W A;  1USH A;  4J6O A;  3QFM A;  4B2O A;  4V0X A;  3C5W C;  2GJU A;  1WAO 1;  3IVE A;  3THO B;  1Z2W A;  1S3N A;  2WDF A;  3H61 A;  4IL1 A;  3LL8 A;  4FBK A;  1S95 A;  2CV9 A;  2USH A;  3H64 A;  3DSC A;  2BDX A;  3KBP A;  4V0W A;  4V0V A;  4LTY A;  1Z2X A;  2DXN A;  4Q7F A;  2Q8U A;  4H2I A;  3E0J A;  4ORA A;  4F0Z A;  5B8I A;  3TGH A;  3THN A;  2NPP C;  2NXF A;  2NYL C;  1NNW A;  2ZBM A;  3GVE A;  4KBP A;  3E7B A;  3IVD A;  3H69 A;  3QFK A;  3K7V C;  3EGH A;  1AUI A;  3FLO A;  3N5U A;  1OID A;  4O5G A;  2WDC A;  1T70 A;  2BCD A;  1QFC A;  1JK7 A;  5GTU A;  4JA9 A;  1FJM A;  2Z1A A;  4MOY A;  3H62 B;  2YEQ A;  3RL3 A;  4O24 A;  2A22 A;  4UT3 A;  1HPU A;  3H60 A;  5JPE A;  3AUZ A;  2IE4 C;  5JJT A;  1V73 A;  1OI8 A;  2HYP A;  3PSO A;  2O8G A;  2O8A A;  4FBW A;  1XZW A;  4KKZ A;  1II7 A;  4ORB A;  4O4K A;  4G9J A;  5DNY A;  2AHD A;  3JYF A;  4UWQ A;  4FBQ A;  1XM7 A;  3RQZ A;  2QJC A;  2QFR A;  4DT2 A;  3CK2 A;  4H2G A;  3T1I A;  4YKE A;  1MF8 A;  3HVQ A;  4FCX A;  3RL4 A;  2Z06 A;  3H67 A;  3QFN A;  4I5N C;  1S3M A;  1HO5 A;  5HPE A;  3ZU0 A;  2DXL A;  3E7A A;  4H2F A;  4ZX2 A;  4WWL A;  2DFJ A;  2ZO9 B;  5J28 A;  4M0V A;  3IB8 A;  2ZOA A;  1S8E A;  1S3L A;  4HD0 A;  2Z72 A;  1TCO A;  3D03 A;  3AV0 A;  3EGG A;  1OIE A;  2JOG A;  2KKN A;  2WDD A;  4NZV A;  4TUI A;  3H63 A;  4IYP C;  1S70 A;  3H66 A;  4H1S A;  1QHW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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