1WARA

Recombinant human purple acid phosphatase expressed in pichia pastoris
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
310
structure length
310
Chain Sequence
EAEAEFATPALRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQILGADFILSLGDNFYFTGVQDINDKRFQETFEDVFSDRSLRKVPWYVLAGNHDHLGNVSAQIAYSKISKRWNFPSPFYRLHFKIPQTNVSVAIFMLDTVTLCGNSDDFLSQQPERPRDVKLARTQLSWLKKQLAAAREDYVLVAGHYPVWSIAEHGPTHCLVKQLRPLLATYGVTAYLCGHDHNLQYLQDENGVGYVLSGAGNFMDPSKRHQRKVPNGYLRFHYGTEDSLGGFAYVEISSKEMTVTYIEASGKSLFKTRLPRRARP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords HUMAN PURPLE ACID PHOSPHATASE
publication title Crystal Structures of Recombinant Human Purple Acid Phosphatase with and without an Inhibitory Conformation of the Repression Loop.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 109
structure length 310
sequence length 310
ec nomenclature ec 3.1.3.2: Acid phosphatase.
pdb deposition date 2004-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 1warA00
4H2FA 2HYPA 3EGGA 2P6BA 4UWQA 5J28A 2IE4C 1S8EA 3GVEA 3KBPA 1WAO1 4WWLA 3PSOA 3ICFA 1HP1A 2BCDA 1M63A 4J6OA 3ZTVA 3H60A 3PSNA 3RQZA 2AHDA 1UTEA 2O8AA 3AUZA 4DSYA 3EGHA 4UT3A 1MF8A 4ZX2A 2Q8UA 3RL4A 1JK7A 3QG5C 2QFRA 5EQVA 1FJMA 1OIEA 4B2OA 5INBA 4V0WA 2NYMC 4ORCA 3IB8A 4FBWA 1OIDA 3QFOA 1S3LA 2DFJA 4ZVZA 3DW8C 3RL5A 2O8GA 3H68A 1AUIA 1S70A 1OI8A 1S3MA 4OR9A 4M0VA 3IB7A 4FCXA 4O5GA 3AV0A 1Z2WA 5IOHA 1NNWA 1UF3A 2YVTA 3LL8A 3H67A 4FBKA 5JPEA 2WDFA 1V73A 4LTYA 2QJCA 3TGHA 2WDCA 4O24A 2JOGA 2GJUA 2ZBMA 1IT6A 2Z1AA 3E7AA 5GTUA 2NPPC 3H66A 3THOB 4LACC 4H2GA 4UT2A 4O4KA 1HO5A 5HPEA 3C5WC 4TUGA 4JA9A 3FGAC 5JPFA 3DSDA 1XM7A 4V0XA 4ORAA 2Z72A 3IVDA 5JJTA 4UT3B 1QFCA 2A22A 5C1VA 2Z06A 3RL3A 4Q7FA 2R17A 3IVEA 2HY1A 3QFMA 1S3NA 4O43A 3H63A 1T70A 1II7A 2QFPA 4LU9A 4ORBA 2NYLC 2XMOA 3H64A 3THNA 5DNYA 3HVQA 4NZVA 3V4YA 2WDDA 5F3WA 4YKEA 4HD0A 1TCOA 4IL1A 1WARA 4JA7A 3H62B 1S95A 3H69A 3C9FA 4I5LC 4TUIA 1U32A 1KBPA 4V0VA 1XZWA 3QFKA 3CK2A 4H1YP 4KKZA 3N5UA 2CV9A 4DHLA 1Z2XA 4I5NC 2USHA 3DSCA 2KKNA 2BDXA 4MOYA 1T71A 3QFNA 3E7BA 3K7VC 2BQ8X 2NXFA 4H2BA 3ZU0A 4G9JA 1G5BA 2IE3C 4FBQA 3K7WC 3H61A 3JYFA 4XPNA 4MP0A 2WDEA 1SU1A 4KBPA 3P71C 4H2IA 4IYPC 1USHA 4F0ZA 5B8IA 1HPUA 4DT2A 4H1SA 4MOVA 1W24A 2HYOA 2IAEC 1QHWA 3T1IA
chains in the Genus database with same CATH superfamily
4H2FA 2HYPA 3EGGA 2P6BA 4UWQA 5J28A 2IE4C 1S8EA 3GVEA 3KBPA 1WAO1 4WWLA 3PSOA 3ICFA 1HP1A 2BCDA 1M63A 4J6OA 3ZTVA 3H60A 3PSNA 3RQZA 2AHDA 1UTEA 2O8AA 3AUZA 4DSYA 3FLOA 2DXNA 3EGHA 4UT3A 1MF8A 2ZO9B 4ZX2A 2Q8UA 3RL4A 1JK7A 3QG5C 2QFRA 5EQVA 1FJMA 1OIEA 4B2OA 5INBA 4V0WA 2NYMC 4ORCA 3IB8A 4FBWA 1OIDA 3QFOA 1S3LA 2DFJA 4ZVZA 2DXLA 3DW8C 3RL5A 2O8GA 3H68A 1AUIA 1S70A 1OI8A 1S3MA 4OR9A 4M0VA 3IB7A 4FCXA 4O5GA 3AV0A 1Z2WA 5IOHA 1NNWA 1UF3A 2YVTA 3LL8A 3H67A 4FBKA 5JPEA 2WDFA 1V73A 4LTYA 2QJCA 3TGHA 2WDCA 4O24A 2JOGA 2GJUA 2ZBMA 1IT6A 2Z1AA 3E7AA 5GTUA 2ZOAA 2NPPC 3H66A 3THOB 4LACC 4H2GA 4UT2A 4O4KA 1HO5A 5HPEA 3C5WC 4TUGA 4JA9A 3FGAC 5JPFA 3DSDA 1XM7A 4V0XA 4ORAA 2Z72A 3IVDA 5JJTA 4UT3B 1QFCA 2A22A 5C1VA 3D03A 2Z06A 3RL3A 4Q7FA 2R17A 3IVEA 2HY1A 3QFMA 1S3NA 4O43A 3H63A 1T70A 1II7A 2QFPA 4LU9A 4ORBA 2NYLC 2XMOA 3H64A 3THNA 5DNYA 3HVQA 4NZVA 3V4YA 2WDDA 5F3WA 4YKEA 4HD0A 1TCOA 4IL1A 1WARA 4JA7A 3H62B 1S95A 3H69A 3C9FA 4I5LC 4TUIA 1U32A 1KBPA 4V0VA 1XZWA 3QFKA 3CK2A 4H1YP 4KKZA 3N5UA 2CV9A 4DHLA 1Z2XA 4I5NC 2USHA 3DSCA 2KKNA 2BDXA 4MOYA 1T71A 3QFNA 3E7BA 3K7VC 2BQ8X 2NXFA 4H2BA 3ZU0A 4G9JA 1G5BA 2IE3C 4FBQA 3K7WC 3H61A 3JYFA 4XPNA 4MP0A 2WDEA 1SU1A 4KBPA 3P71C 4H2IA 4IYPC 1USHA 4F0ZA 5B8IA 1HPUA 2YEQA 3E0JA 4DT2A 4H1SA 4MOVA 1W24A 2HYOA 2IAEC 1QHWA 3T1IA
chains in the Genus database with same CATH topology
4H2FA 2HYPA 3EGGA 2P6BA 4UWQA 5J28A 2IE4C 1S8EA 3GVEA 3KBPA 1WAO1 4WWLA 3PSOA 3ICFA 1HP1A 2BCDA 1M63A 4J6OA 3ZTVA 3H60A 3PSNA 3RQZA 2AHDA 1UTEA 2O8AA 3AUZA 4DSYA 3FLOA 2DXNA 3EGHA 4UT3A 1MF8A 2ZO9B 4ZX2A 2Q8UA 3RL4A 1JK7A 3QG5C 2QFRA 5EQVA 1FJMA 1OIEA 4B2OA 5INBA 4V0WA 2NYMC 4ORCA 3IB8A 4FBWA 1OIDA 3QFOA 1S3LA 2DFJA 4ZVZA 2DXLA 3DW8C 3RL5A 2O8GA 3H68A 1AUIA 1S70A 1OI8A 1S3MA 4OR9A 4M0VA 3IB7A 4FCXA 4O5GA 3AV0A 1Z2WA 5IOHA 1NNWA 1UF3A 2YVTA 3LL8A 3H67A 4FBKA 5JPEA 2WDFA 1V73A 4LTYA 2QJCA 3TGHA 2WDCA 4O24A 2JOGA 2GJUA 2ZBMA 1IT6A 2Z1AA 3E7AA 5GTUA 2ZOAA 2NPPC 3H66A 3THOB 4LACC 4H2GA 4UT2A 4O4KA 1HO5A 5HPEA 3C5WC 4TUGA 4JA9A 3FGAC 5JPFA 3DSDA 1XM7A 4V0XA 4ORAA 2Z72A 3IVDA 5JJTA 4UT3B 1QFCA 2A22A 5C1VA 3D03A 2Z06A 3RL3A 4Q7FA 2R17A 3IVEA 2HY1A 3QFMA 1S3NA 4O43A 3H63A 1T70A 1II7A 2QFPA 4LU9A 4ORBA 2NYLC 2XMOA 3H64A 3THNA 5DNYA 3HVQA 4NZVA 3V4YA 2WDDA 5F3WA 4YKEA 4HD0A 1TCOA 4IL1A 1WARA 4JA7A 3H62B 1S95A 3H69A 3C9FA 4I5LC 4TUIA 1U32A 1KBPA 4V0VA 1XZWA 3QFKA 3CK2A 4H1YP 4KKZA 3N5UA 2CV9A 4DHLA 1Z2XA 4I5NC 2USHA 3DSCA 2KKNA 2BDXA 4MOYA 1T71A 3QFNA 3E7BA 3K7VC 2BQ8X 2NXFA 4H2BA 3ZU0A 4G9JA 1G5BA 2IE3C 4FBQA 3K7WC 3H61A 3JYFA 4XPNA 4MP0A 2WDEA 1SU1A 4KBPA 3P71C 4H2IA 4IYPC 1USHA 4F0ZA 5B8IA 1HPUA 2YEQA 3E0JA 4DT2A 4H1SA 4MOVA 1W24A 2HYOA 2IAEC 1QHWA 3T1IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H2F A;  2HYP A;  3EGG A;  2P6B A;  4UWQ A;  5J28 A;  2IE4 C;  1S8E A;  3GVE A;  3KBP A;  1WAO 1;  4WWL A;  3PSO A;  3ICF A;  1HP1 A;  2BCD A;  1M63 A;  4J6O A;  3ZTV A;  3H60 A;  3PSN A;  3RQZ A;  2AHD A;  1UTE A;  2O8A A;  3AUZ A;  4DSY A;  3EGH A;  4UT3 A;  1MF8 A;  4ZX2 A;  2Q8U A;  3RL4 A;  1JK7 A;  3QG5 C;  2QFR A;  5EQV A;  1FJM A;  1OIE A;  4B2O A;  5INB A;  4V0W A;  2NYM C;  4ORC A;  3IB8 A;  4FBW A;  1OID A;  3QFO A;  1S3L A;  2DFJ A;  4ZVZ A;  3DW8 C;  3RL5 A;  2O8G A;  3H68 A;  1AUI A;  1S70 A;  1OI8 A;  1S3M A;  4OR9 A;  4M0V A;  3IB7 A;  4FCX A;  4O5G A;  3AV0 A;  1Z2W A;  5IOH A;  1NNW A;  1UF3 A;  2YVT A;  3LL8 A;  3H67 A;  4FBK A;  5JPE A;  2WDF A;  1V73 A;  4LTY A;  2QJC A;  3TGH A;  2WDC A;  4O24 A;  2JOG A;  2GJU A;  2ZBM A;  1IT6 A;  2Z1A A;  3E7A A;  5GTU A;  2NPP C;  3H66 A;  3THO B;  4LAC C;  4H2G A;  4UT2 A;  4O4K A;  1HO5 A;  5HPE A;  3C5W C;  4TUG A;  4JA9 A;  3FGA C;  5JPF A;  3DSD A;  1XM7 A;  4V0X A;  4ORA A;  2Z72 A;  3IVD A;  5JJT A;  4UT3 B;  1QFC A;  2A22 A;  5C1V A;  2Z06 A;  3RL3 A;  4Q7F A;  2R17 A;  3IVE A;  2HY1 A;  3QFM A;  1S3N A;  4O43 A;  3H63 A;  1T70 A;  1II7 A;  2QFP A;  4LU9 A;  4ORB A;  2NYL C;  2XMO A;  3H64 A;  3THN A;  5DNY A;  3HVQ A;  4NZV A;  3V4Y A;  2WDD A;  5F3W A;  4YKE A;  4HD0 A;  1TCO A;  4IL1 A;  1WAR A;  4JA7 A;  3H62 B;  1S95 A;  3H69 A;  3C9F A;  4I5L C;  4TUI A;  1U32 A;  1KBP A;  4V0V A;  1XZW A;  3QFK A;  3CK2 A;  4H1Y P;  4KKZ A;  3N5U A;  2CV9 A;  4DHL A;  1Z2X A;  4I5N C;  2USH A;  3DSC A;  2KKN A;  2BDX A;  4MOY A;  1T71 A;  3QFN A;  3E7B A;  3K7V C;  2BQ8 X;  2NXF A;  4H2B A;  3ZU0 A;  4G9J A;  1G5B A;  2IE3 C;  4FBQ A;  3K7W C;  3H61 A;  3JYF A;  4XPN A;  4MP0 A;  2WDE A;  1SU1 A;  4KBP A;  3P71 C;  4H2I A;  4IYP C;  1USH A;  4F0Z A;  5B8I A;  1HPU A;  4DT2 A;  4H1S A;  4MOV A;  1W24 A;  2HYO A;  2IAE C;  1QHW A;  3T1I A; 
#chains in the Genus database with same CATH topology
 4H2F A;  2HYP A;  3EGG A;  2P6B A;  4UWQ A;  5J28 A;  2IE4 C;  1S8E A;  3GVE A;  3KBP A;  1WAO 1;  4WWL A;  3PSO A;  3ICF A;  1HP1 A;  2BCD A;  1M63 A;  4J6O A;  3ZTV A;  3H60 A;  3PSN A;  3RQZ A;  2AHD A;  1UTE A;  2O8A A;  3AUZ A;  4DSY A;  3FLO A;  2DXN A;  3EGH A;  4UT3 A;  1MF8 A;  2ZO9 B;  4ZX2 A;  2Q8U A;  3RL4 A;  1JK7 A;  3QG5 C;  2QFR A;  5EQV A;  1FJM A;  1OIE A;  4B2O A;  5INB A;  4V0W A;  2NYM C;  4ORC A;  3IB8 A;  4FBW A;  1OID A;  3QFO A;  1S3L A;  2DFJ A;  4ZVZ A;  2DXL A;  3DW8 C;  3RL5 A;  2O8G A;  3H68 A;  1AUI A;  1S70 A;  1OI8 A;  1S3M A;  4OR9 A;  4M0V A;  3IB7 A;  4FCX A;  4O5G A;  3AV0 A;  1Z2W A;  5IOH A;  1NNW A;  1UF3 A;  2YVT A;  3LL8 A;  3H67 A;  4FBK A;  5JPE A;  2WDF A;  1V73 A;  4LTY A;  2QJC A;  3TGH A;  2WDC A;  4O24 A;  2JOG A;  2GJU A;  2ZBM A;  1IT6 A;  2Z1A A;  3E7A A;  5GTU A;  2ZOA A;  2NPP C;  3H66 A;  3THO B;  4LAC C;  4H2G A;  4UT2 A;  4O4K A;  1HO5 A;  5HPE A;  3C5W C;  4TUG A;  4JA9 A;  3FGA C;  5JPF A;  3DSD A;  1XM7 A;  4V0X A;  4ORA A;  2Z72 A;  3IVD A;  5JJT A;  4UT3 B;  1QFC A;  2A22 A;  5C1V A;  3D03 A;  2Z06 A;  3RL3 A;  4Q7F A;  2R17 A;  3IVE A;  2HY1 A;  3QFM A;  1S3N A;  4O43 A;  3H63 A;  1T70 A;  1II7 A;  2QFP A;  4LU9 A;  4ORB A;  2NYL C;  2XMO A;  3H64 A;  3THN A;  5DNY A;  3HVQ A;  4NZV A;  3V4Y A;  2WDD A;  5F3W A;  4YKE A;  4HD0 A;  1TCO A;  4IL1 A;  1WAR A;  4JA7 A;  3H62 B;  1S95 A;  3H69 A;  3C9F A;  4I5L C;  4TUI A;  1U32 A;  1KBP A;  4V0V A;  1XZW A;  3QFK A;  3CK2 A;  4H1Y P;  4KKZ A;  3N5U A;  2CV9 A;  4DHL A;  1Z2X A;  4I5N C;  2USH A;  3DSC A;  2KKN A;  2BDX A;  4MOY A;  1T71 A;  3QFN A;  3E7B A;  3K7V C;  2BQ8 X;  2NXF A;  4H2B A;  3ZU0 A;  4G9J A;  1G5B A;  2IE3 C;  4FBQ A;  3K7W C;  3H61 A;  3JYF A;  4XPN A;  4MP0 A;  2WDE A;  1SU1 A;  4KBP A;  3P71 C;  4H2I A;  4IYP C;  1USH A;  4F0Z A;  5B8I A;  1HPU A;  2YEQ A;  3E0J A;  4DT2 A;  4H1S A;  4MOV A;  1W24 A;  2HYO A;  2IAE C;  1QHW A;  3T1I A; 
#chains in the Genus database with same CATH homology
 4H2F A;  2HYP A;  3EGG A;  2P6B A;  4UWQ A;  5J28 A;  2IE4 C;  1S8E A;  3GVE A;  3KBP A;  1WAO 1;  4WWL A;  3PSO A;  3ICF A;  1HP1 A;  2BCD A;  1M63 A;  4J6O A;  3ZTV A;  3H60 A;  3PSN A;  3RQZ A;  2AHD A;  1UTE A;  2O8A A;  3AUZ A;  4DSY A;  3FLO A;  2DXN A;  3EGH A;  4UT3 A;  1MF8 A;  2ZO9 B;  4ZX2 A;  2Q8U A;  3RL4 A;  1JK7 A;  3QG5 C;  2QFR A;  5EQV A;  1FJM A;  1OIE A;  4B2O A;  5INB A;  4V0W A;  2NYM C;  4ORC A;  3IB8 A;  4FBW A;  1OID A;  3QFO A;  1S3L A;  2DFJ A;  4ZVZ A;  2DXL A;  3DW8 C;  3RL5 A;  2O8G A;  3H68 A;  1AUI A;  1S70 A;  1OI8 A;  1S3M A;  4OR9 A;  4M0V A;  3IB7 A;  4FCX A;  4O5G A;  3AV0 A;  1Z2W A;  5IOH A;  1NNW A;  1UF3 A;  2YVT A;  3LL8 A;  3H67 A;  4FBK A;  5JPE A;  2WDF A;  1V73 A;  4LTY A;  2QJC A;  3TGH A;  2WDC A;  4O24 A;  2JOG A;  2GJU A;  2ZBM A;  1IT6 A;  2Z1A A;  3E7A A;  5GTU A;  2ZOA A;  2NPP C;  3H66 A;  3THO B;  4LAC C;  4H2G A;  4UT2 A;  4O4K A;  1HO5 A;  5HPE A;  3C5W C;  4TUG A;  4JA9 A;  3FGA C;  5JPF A;  3DSD A;  1XM7 A;  4V0X A;  4ORA A;  2Z72 A;  3IVD A;  5JJT A;  4UT3 B;  1QFC A;  2A22 A;  5C1V A;  3D03 A;  2Z06 A;  3RL3 A;  4Q7F A;  2R17 A;  3IVE A;  2HY1 A;  3QFM A;  1S3N A;  4O43 A;  3H63 A;  1T70 A;  1II7 A;  2QFP A;  4LU9 A;  4ORB A;  2NYL C;  2XMO A;  3H64 A;  3THN A;  5DNY A;  3HVQ A;  4NZV A;  3V4Y A;  2WDD A;  5F3W A;  4YKE A;  4HD0 A;  1TCO A;  4IL1 A;  1WAR A;  4JA7 A;  3H62 B;  1S95 A;  3H69 A;  3C9F A;  4I5L C;  4TUI A;  1U32 A;  1KBP A;  4V0V A;  1XZW A;  3QFK A;  3CK2 A;  4H1Y P;  4KKZ A;  3N5U A;  2CV9 A;  4DHL A;  1Z2X A;  4I5N C;  2USH A;  3DSC A;  2KKN A;  2BDX A;  4MOY A;  1T71 A;  3QFN A;  3E7B A;  3K7V C;  2BQ8 X;  2NXF A;  4H2B A;  3ZU0 A;  4G9J A;  1G5B A;  2IE3 C;  4FBQ A;  3K7W C;  3H61 A;  3JYF A;  4XPN A;  4MP0 A;  2WDE A;  1SU1 A;  4KBP A;  3P71 C;  4H2I A;  4IYP C;  1USH A;  4F0Z A;  5B8I A;  1HPU A;  2YEQ A;  3E0J A;  4DT2 A;  4H1S A;  4MOV A;  1W24 A;  2HYO A;  2IAE C;  1QHW A;  3T1I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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