2O8GA

Rat pp1c gamma complexed with mouse inhibitor-2
Total Genus 111
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
111
sequence length
295
structure length
295
Chain Sequence
KLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for regulation of protein phosphatase 1 by inhibitor-2.
pubmed doi rcsb
molecule tags Hydrolase/inhibitor
source organism Rattus norvegicus
molecule keywords Serine/threonine-protein phosphatase PP1-gamma catalytic sub
total genus 111
structure length 295
sequence length 295
chains with identical sequence B
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2006-12-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2o8gA00
1OIEA 1IT6A 3H66A 4LU9A 3IVDA 2NYMC 1S70A 3H63A 5C1VA 4WWLA 2USHA 3QFNA 1II7A 4ZVZA 5DNYA 3RL5A 3QFKA 3K7WC 4ORAA 2BQ8X 5IOHA 4I5NC 3P71C 3AUZA 1U32A 2IAEC 2NXFA 4V0VA 2WDEA 3KBPA 5J28A 4KBPA 4OR9A 2WDCA 3GVEA 1W24A 3H62B 1JK7A 4YKEA 3V4YA 4TUGA 3DSCA 2R17A 5EQVA 3RL3A 1UF3A 5INBA 5JPFA 1XZWA 4ORCA 4NZVA 1FJMA 3N5UA 2BCDA 4DT2A 4UT2A 5JJTA 1AUIA 1USHA 2A22A 2Q8UA 2QFRA 3H64A 1HP1A 3FGAC 1NNWA 2ZBMA 3JYFA 3LL8A 2DFJA 3H68A 2NYLC 1Z2XA 4H2GA 4JA7A 2HYPA 4I5LC 3T1IA 4DHLA 4DSYA 3H69A 4J6OA 1XM7A 1V73A 2YVTA 3C9FA 1SU1A 3PSOA 3ZTVA 4IYPC 3IB8A 3IB7A 4ZX2A 1S95A 4O43A 3TGHA 4FCXA 2AHDA 3ICFA 1OIDA 4FBQA 4MP0A 4LACC 2CV9A 4XPNA 2WDDA 4IL1A 1OI8A 3DSDA 2IE3C 4H2FA 5F3WA 2Z72A 4LTYA 2QJCA 4V0WA 2JOGA 3IVEA 4H1SA 4F0ZA 5JPEA 4H2IA 3HVQA 2QFPA 3H60A 4ORBA 1HPUA 2Z1AA 3AV0A 2NPPC 1Z2WA 4MOVA 4H2BA 2Z06A 4O5GA 1M63A 3EGHA 1QHWA 1WARA 1T71A 4O4KA 3EGGA 4JA9A 3E7AA 1WAO1 1QFCA 2BDXA 5GTUA 3C5WC 4UT3A 3K7VC 4FBWA 1KBPA 2O8GA 1S3MA 3DW8C 4M0VA 3RL4A 3H67A 2IE4C 2P6BA 4FBKA 4KKZA 4HD0A 2KKNA 2HY1A 3QFMA 4H1YP 4V0XA 3CK2A 4MOYA 3THNA 1S3NA 3THOB 4UWQA 3ZU0A 2HYOA 3H61A 4G9JA 1S8EA 1MF8A 2O8AA 3PSNA 2WDFA 3QG5C 3RQZA 5B8IA 5HPEA 1UTEA 1S3LA 1TCOA 1G5BA 3E7BA 4Q7FA 4O24A 1HO5A 1T70A 4B2OA 2XMOA 2GJUA 4TUIA 3QFOA 4UT3B
chains in the Genus database with same CATH superfamily
1OIEA 1IT6A 3H66A 4LU9A 3IVDA 2NYMC 1S70A 3H63A 5C1VA 4WWLA 2USHA 3QFNA 1II7A 4ZVZA 5DNYA 3RL5A 3QFKA 3K7WC 4ORAA 2BQ8X 5IOHA 4I5NC 3P71C 3AUZA 1U32A 2IAEC 2NXFA 4V0VA 2WDEA 3KBPA 5J28A 4KBPA 4OR9A 2WDCA 3GVEA 1W24A 3H62B 1JK7A 4YKEA 3V4YA 4TUGA 3DSCA 2ZO9B 2R17A 5EQVA 3RL3A 1UF3A 5INBA 5JPFA 1XZWA 4ORCA 4NZVA 1FJMA 3N5UA 2BCDA 4DT2A 4UT2A 5JJTA 1AUIA 1USHA 2A22A 2Q8UA 2QFRA 3H64A 1HP1A 3FGAC 1NNWA 2ZBMA 3JYFA 3LL8A 2DFJA 3H68A 2NYLC 1Z2XA 4H2GA 4JA7A 2HYPA 4I5LC 3T1IA 4DHLA 4DSYA 3H69A 4J6OA 1XM7A 1V73A 2YVTA 3C9FA 1SU1A 2DXLA 3PSOA 3ZTVA 4IYPC 3IB8A 3IB7A 4ZX2A 1S95A 4O43A 3TGHA 4FCXA 2AHDA 3ICFA 1OIDA 4FBQA 4MP0A 4LACC 2CV9A 4XPNA 2WDDA 4IL1A 1OI8A 3DSDA 2IE3C 4H2FA 5F3WA 4UT3B 2Z72A 4LTYA 2QJCA 4V0WA 2JOGA 3IVEA 4H1SA 4F0ZA 5JPEA 4H2IA 3HVQA 2QFPA 3H60A 4ORBA 1HPUA 2Z1AA 3AV0A 2NPPC 1Z2WA 3E0JA 4MOVA 4H2BA 2Z06A 4O5GA 1M63A 2DXNA 3EGHA 1QHWA 1WARA 1T71A 2YEQA 3EGGA 4JA9A 4O4KA 3E7AA 1WAO1 1QFCA 2BDXA 5GTUA 3C5WC 4UT3A 3K7VC 4FBWA 1KBPA 2O8GA 1S3MA 2ZOAA 3DW8C 4M0VA 3RL4A 3H67A 2IE4C 2P6BA 4FBKA 4KKZA 4HD0A 2KKNA 2HY1A 3QFMA 4H1YP 4V0XA 3CK2A 4MOYA 3THNA 1S3NA 3THOB 4UWQA 3FLOA 3ZU0A 2HYOA 3H61A 4G9JA 1S8EA 1MF8A 2O8AA 3PSNA 2WDFA 3QG5C 3RQZA 5B8IA 5HPEA 1UTEA 1S3LA 1TCOA 1G5BA 3E7BA 4Q7FA 4O24A 1HO5A 1T70A 4B2OA 2XMOA 2GJUA 4TUIA 3QFOA 3D03A
chains in the Genus database with same CATH topology
1OIEA 1IT6A 3H66A 4LU9A 3IVDA 2NYMC 1S70A 3H63A 5C1VA 4WWLA 2USHA 3QFNA 1II7A 4ZVZA 5DNYA 3RL5A 3QFKA 3K7WC 4ORAA 2BQ8X 5IOHA 4I5NC 3P71C 3AUZA 1U32A 2IAEC 2NXFA 4V0VA 2WDEA 3KBPA 5J28A 4KBPA 4OR9A 2WDCA 3GVEA 1W24A 3H62B 1JK7A 4YKEA 3V4YA 4TUGA 3DSCA 2ZO9B 2R17A 5EQVA 3RL3A 1UF3A 5INBA 5JPFA 1XZWA 4ORCA 4NZVA 1FJMA 3N5UA 2BCDA 4DT2A 4UT2A 5JJTA 1AUIA 1USHA 2A22A 2Q8UA 2QFRA 3H64A 1HP1A 3FGAC 1NNWA 2ZBMA 3JYFA 3LL8A 2DFJA 3H68A 2NYLC 1Z2XA 4H2GA 4JA7A 2HYPA 4I5LC 3T1IA 4DHLA 4DSYA 3H69A 4J6OA 1XM7A 1V73A 2YVTA 3C9FA 1SU1A 2DXLA 3PSOA 3ZTVA 4IYPC 3IB8A 3IB7A 4ZX2A 1S95A 4O43A 3TGHA 4FCXA 2AHDA 3ICFA 1OIDA 4FBQA 4MP0A 4LACC 2CV9A 4XPNA 2WDDA 4IL1A 1OI8A 3DSDA 2IE3C 4H2FA 5F3WA 4UT3B 2Z72A 4LTYA 2QJCA 4V0WA 2JOGA 3IVEA 4H1SA 4F0ZA 5JPEA 4H2IA 3HVQA 2QFPA 3H60A 4ORBA 1HPUA 2Z1AA 3AV0A 2NPPC 1Z2WA 3E0JA 4MOVA 4H2BA 2Z06A 4O5GA 1M63A 2DXNA 3EGHA 1QHWA 1WARA 1T71A 2YEQA 3EGGA 4JA9A 4O4KA 3E7AA 1WAO1 1QFCA 2BDXA 5GTUA 3C5WC 4UT3A 3K7VC 4FBWA 1KBPA 2O8GA 1S3MA 2ZOAA 3DW8C 4M0VA 3RL4A 3H67A 2IE4C 2P6BA 4FBKA 4KKZA 4HD0A 2KKNA 2HY1A 3QFMA 4H1YP 4V0XA 3CK2A 4MOYA 3THNA 1S3NA 3THOB 4UWQA 3FLOA 3ZU0A 2HYOA 3H61A 4G9JA 1S8EA 1MF8A 2O8AA 3PSNA 2WDFA 3QG5C 3RQZA 5B8IA 5HPEA 1UTEA 1S3LA 1TCOA 1G5BA 3E7BA 4Q7FA 4O24A 1HO5A 1T70A 4B2OA 2XMOA 2GJUA 4TUIA 3QFOA 3D03A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OIE A;  1IT6 A;  3H66 A;  4LU9 A;  3IVD A;  2NYM C;  1S70 A;  3H63 A;  5C1V A;  4WWL A;  2USH A;  3QFN A;  1II7 A;  4ZVZ A;  5DNY A;  3RL5 A;  3QFK A;  3K7W C;  4ORA A;  2BQ8 X;  5IOH A;  4I5N C;  3P71 C;  3AUZ A;  1U32 A;  2IAE C;  2NXF A;  4V0V A;  2WDE A;  3KBP A;  5J28 A;  4KBP A;  4OR9 A;  2WDC A;  3GVE A;  1W24 A;  3H62 B;  1JK7 A;  4YKE A;  3V4Y A;  4TUG A;  3DSC A;  2R17 A;  5EQV A;  3RL3 A;  1UF3 A;  5INB A;  5JPF A;  1XZW A;  4ORC A;  4NZV A;  1FJM A;  3N5U A;  2BCD A;  4DT2 A;  4UT2 A;  5JJT A;  1AUI A;  1USH A;  2A22 A;  2Q8U A;  2QFR A;  3H64 A;  1HP1 A;  3FGA C;  1NNW A;  2ZBM A;  3JYF A;  3LL8 A;  2DFJ A;  3H68 A;  2NYL C;  1Z2X A;  4H2G A;  4JA7 A;  2HYP A;  4I5L C;  3T1I A;  4DHL A;  4DSY A;  3H69 A;  4J6O A;  1XM7 A;  1V73 A;  2YVT A;  3C9F A;  1SU1 A;  3PSO A;  3ZTV A;  4IYP C;  3IB8 A;  3IB7 A;  4ZX2 A;  1S95 A;  4O43 A;  3TGH A;  4FCX A;  2AHD A;  3ICF A;  1OID A;  4FBQ A;  4MP0 A;  4LAC C;  2CV9 A;  4XPN A;  2WDD A;  4IL1 A;  1OI8 A;  3DSD A;  2IE3 C;  4H2F A;  5F3W A;  2Z72 A;  4LTY A;  2QJC A;  4V0W A;  2JOG A;  3IVE A;  4H1S A;  4F0Z A;  5JPE A;  4H2I A;  3HVQ A;  2QFP A;  3H60 A;  4ORB A;  1HPU A;  2Z1A A;  3AV0 A;  2NPP C;  1Z2W A;  4MOV A;  4H2B A;  2Z06 A;  4O5G A;  1M63 A;  3EGH A;  1QHW A;  1WAR A;  1T71 A;  4O4K A;  3EGG A;  4JA9 A;  3E7A A;  1WAO 1;  1QFC A;  2BDX A;  5GTU A;  3C5W C;  4UT3 A;  3K7V C;  4FBW A;  1KBP A;  2O8G A;  1S3M A;  3DW8 C;  4M0V A;  3RL4 A;  3H67 A;  2IE4 C;  2P6B A;  4FBK A;  4KKZ A;  4HD0 A;  2KKN A;  2HY1 A;  3QFM A;  4H1Y P;  4V0X A;  3CK2 A;  4MOY A;  3THN A;  1S3N A;  3THO B;  4UWQ A;  3ZU0 A;  2HYO A;  3H61 A;  4G9J A;  1S8E A;  1MF8 A;  2O8A A;  3PSN A;  2WDF A;  3QG5 C;  3RQZ A;  5B8I A;  5HPE A;  1UTE A;  1S3L A;  1TCO A;  1G5B A;  3E7B A;  4Q7F A;  4O24 A;  1HO5 A;  1T70 A;  4B2O A;  2XMO A;  2GJU A;  4TUI A;  3QFO A;  4UT3 B; 
#chains in the Genus database with same CATH topology
 1OIE A;  1IT6 A;  3H66 A;  4LU9 A;  3IVD A;  2NYM C;  1S70 A;  3H63 A;  5C1V A;  4WWL A;  2USH A;  3QFN A;  1II7 A;  4ZVZ A;  5DNY A;  3RL5 A;  3QFK A;  3K7W C;  4ORA A;  2BQ8 X;  5IOH A;  4I5N C;  3P71 C;  3AUZ A;  1U32 A;  2IAE C;  2NXF A;  4V0V A;  2WDE A;  3KBP A;  5J28 A;  4KBP A;  4OR9 A;  2WDC A;  3GVE A;  1W24 A;  3H62 B;  1JK7 A;  4YKE A;  3V4Y A;  4TUG A;  3DSC A;  2ZO9 B;  2R17 A;  5EQV A;  3RL3 A;  1UF3 A;  5INB A;  5JPF A;  1XZW A;  4ORC A;  4NZV A;  1FJM A;  3N5U A;  2BCD A;  4DT2 A;  4UT2 A;  5JJT A;  1AUI A;  1USH A;  2A22 A;  2Q8U A;  2QFR A;  3H64 A;  1HP1 A;  3FGA C;  1NNW A;  2ZBM A;  3JYF A;  3LL8 A;  2DFJ A;  3H68 A;  2NYL C;  1Z2X A;  4H2G A;  4JA7 A;  2HYP A;  4I5L C;  3T1I A;  4DHL A;  4DSY A;  3H69 A;  4J6O A;  1XM7 A;  1V73 A;  2YVT A;  3C9F A;  1SU1 A;  2DXL A;  3PSO A;  3ZTV A;  4IYP C;  3IB8 A;  3IB7 A;  4ZX2 A;  1S95 A;  4O43 A;  3TGH A;  4FCX A;  2AHD A;  3ICF A;  1OID A;  4FBQ A;  4MP0 A;  4LAC C;  2CV9 A;  4XPN A;  2WDD A;  4IL1 A;  1OI8 A;  3DSD A;  2IE3 C;  4H2F A;  5F3W A;  4UT3 B;  2Z72 A;  4LTY A;  2QJC A;  4V0W A;  2JOG A;  3IVE A;  4H1S A;  4F0Z A;  5JPE A;  4H2I A;  3HVQ A;  2QFP A;  3H60 A;  4ORB A;  1HPU A;  2Z1A A;  3AV0 A;  2NPP C;  1Z2W A;  3E0J A;  4MOV A;  4H2B A;  2Z06 A;  4O5G A;  1M63 A;  2DXN A;  3EGH A;  1QHW A;  1WAR A;  1T71 A;  2YEQ A;  3EGG A;  4JA9 A;  4O4K A;  3E7A A;  1WAO 1;  1QFC A;  2BDX A;  5GTU A;  3C5W C;  4UT3 A;  3K7V C;  4FBW A;  1KBP A;  2O8G A;  1S3M A;  2ZOA A;  3DW8 C;  4M0V A;  3RL4 A;  3H67 A;  2IE4 C;  2P6B A;  4FBK A;  4KKZ A;  4HD0 A;  2KKN A;  2HY1 A;  3QFM A;  4H1Y P;  4V0X A;  3CK2 A;  4MOY A;  3THN A;  1S3N A;  3THO B;  4UWQ A;  3FLO A;  3ZU0 A;  2HYO A;  3H61 A;  4G9J A;  1S8E A;  1MF8 A;  2O8A A;  3PSN A;  2WDF A;  3QG5 C;  3RQZ A;  5B8I A;  5HPE A;  1UTE A;  1S3L A;  1TCO A;  1G5B A;  3E7B A;  4Q7F A;  4O24 A;  1HO5 A;  1T70 A;  4B2O A;  2XMO A;  2GJU A;  4TUI A;  3QFO A;  3D03 A; 
#chains in the Genus database with same CATH homology
 1OIE A;  1IT6 A;  3H66 A;  4LU9 A;  3IVD A;  2NYM C;  1S70 A;  3H63 A;  5C1V A;  4WWL A;  2USH A;  3QFN A;  1II7 A;  4ZVZ A;  5DNY A;  3RL5 A;  3QFK A;  3K7W C;  4ORA A;  2BQ8 X;  5IOH A;  4I5N C;  3P71 C;  3AUZ A;  1U32 A;  2IAE C;  2NXF A;  4V0V A;  2WDE A;  3KBP A;  5J28 A;  4KBP A;  4OR9 A;  2WDC A;  3GVE A;  1W24 A;  3H62 B;  1JK7 A;  4YKE A;  3V4Y A;  4TUG A;  3DSC A;  2ZO9 B;  2R17 A;  5EQV A;  3RL3 A;  1UF3 A;  5INB A;  5JPF A;  1XZW A;  4ORC A;  4NZV A;  1FJM A;  3N5U A;  2BCD A;  4DT2 A;  4UT2 A;  5JJT A;  1AUI A;  1USH A;  2A22 A;  2Q8U A;  2QFR A;  3H64 A;  1HP1 A;  3FGA C;  1NNW A;  2ZBM A;  3JYF A;  3LL8 A;  2DFJ A;  3H68 A;  2NYL C;  1Z2X A;  4H2G A;  4JA7 A;  2HYP A;  4I5L C;  3T1I A;  4DHL A;  4DSY A;  3H69 A;  4J6O A;  1XM7 A;  1V73 A;  2YVT A;  3C9F A;  1SU1 A;  2DXL A;  3PSO A;  3ZTV A;  4IYP C;  3IB8 A;  3IB7 A;  4ZX2 A;  1S95 A;  4O43 A;  3TGH A;  4FCX A;  2AHD A;  3ICF A;  1OID A;  4FBQ A;  4MP0 A;  4LAC C;  2CV9 A;  4XPN A;  2WDD A;  4IL1 A;  1OI8 A;  3DSD A;  2IE3 C;  4H2F A;  5F3W A;  4UT3 B;  2Z72 A;  4LTY A;  2QJC A;  4V0W A;  2JOG A;  3IVE A;  4H1S A;  4F0Z A;  5JPE A;  4H2I A;  3HVQ A;  2QFP A;  3H60 A;  4ORB A;  1HPU A;  2Z1A A;  3AV0 A;  2NPP C;  1Z2W A;  3E0J A;  4MOV A;  4H2B A;  2Z06 A;  4O5G A;  1M63 A;  2DXN A;  3EGH A;  1QHW A;  1WAR A;  1T71 A;  2YEQ A;  3EGG A;  4JA9 A;  4O4K A;  3E7A A;  1WAO 1;  1QFC A;  2BDX A;  5GTU A;  3C5W C;  4UT3 A;  3K7V C;  4FBW A;  1KBP A;  2O8G A;  1S3M A;  2ZOA A;  3DW8 C;  4M0V A;  3RL4 A;  3H67 A;  2IE4 C;  2P6B A;  4FBK A;  4KKZ A;  4HD0 A;  2KKN A;  2HY1 A;  3QFM A;  4H1Y P;  4V0X A;  3CK2 A;  4MOY A;  3THN A;  1S3N A;  3THO B;  4UWQ A;  3FLO A;  3ZU0 A;  2HYO A;  3H61 A;  4G9J A;  1S8E A;  1MF8 A;  2O8A A;  3PSN A;  2WDF A;  3QG5 C;  3RQZ A;  5B8I A;  5HPE A;  1UTE A;  1S3L A;  1TCO A;  1G5B A;  3E7B A;  4Q7F A;  4O24 A;  1HO5 A;  1T70 A;  4B2O A;  2XMO A;  2GJU A;  4TUI A;  3QFO A;  3D03 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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