5GTUA

Structural and mechanistic insights into regulation of the retromer coat by tbc1d5
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
186
structure length
186
Chain Sequence
MAGHRLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Vacuolar protein sorting-associated protein 29
publication title Structural and mechanistic insights into regulation of the retromer coat by TBC1d5
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 49
structure length 186
sequence length 186
ec nomenclature
pdb deposition date 2016-08-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 5gtuA00
5HPEA 3GVEA 3H61A 3T1IA 1S3NA 1HPUA 1Z2WA 4DHLA 4UT2A 1S70A 2ZBMA 5JPEA 3QFOA 3FGAC 4I5LC 1SU1A 1AUIA 1WARA 2WDDA 4MOYA 3RQZA 4J6OA 2O8AA 1S95A 2Z1AA 4UT3A 5J28A 4MOVA 2A22A 1QHWA 1Z2XA 4H1YP 1FJMA 4TUIA 2DFJA 5INBA 1JK7A 2WDFA 3RL4A 5F3WA 4V0WA 2WDEA 1T71A 1OIEA 3ICFA 4JA7A 2KKNA 3IB7A 4DT2A 1S3MA 1S3LA 5EQVA 4ORBA 1HO5A 2CV9A 1T70A 3DSDA 3RL3A 4ZX2A 1USHA 4FBWA 4FBQA 3IVEA 3H62B 4ORAA 2BDXA 2WDCA 1UF3A 2O8GA 4OR9A 4YKEA 2XMOA 4JA9A 1G5BA 4FCXA 1S8EA 4V0XA 3H64A 1W24A 3ZTVA 3P71C 4O43A 3IB8A 1WAO1 1OI8A 2Z72A 4H1SA 4H2IA 4LACC 4F0ZA 3QG5C 3IVDA 1OIDA 2NYMC 4LTYA 3H68A 2HYOA 4O5GA 1TCOA 1HP1A 3HVQA 3JYFA 3AUZA 3LL8A 4NZVA 2NXFA 2P6BA 3E7BA 3H66A 4KBPA 4B2OA 1II7A 4IYPC 4KKZA 2AHDA 4ORCA 3DW8C 2IAEC 4H2FA 5GTUA 1IT6A 1NNWA 2BQ8X 3EGHA 3ZU0A 4O24A 3DSCA 1QFCA 4O4KA 3QFNA 1UTEA 4I5NC 3TGHA 3RL5A 3E7AA 2HYPA 3QFMA 4WWLA 5B8IA 2IE3C 2Q8UA 3AV0A 4TUGA 2QFRA 3H60A 4Q7FA 4IL1A 4MP0A 3V4YA 5JJTA 2JOGA 1M63A 5C1VA 4H2BA 2USHA 3PSNA 1MF8A 2NPPC 3KBPA 2YVTA 4UWQA 4V0VA 3H69A 3CK2A 4LU9A 2R17A 2Z06A 3H67A 4XPNA 3K7WC 3C5WC 4M0VA 2IE4C 3K7VC 3N5UA 2QJCA 4G9JA 4UT3B 4ZVZA 3EGGA 4H2GA 3H63A 5IOHA 2HY1A 3C9FA 4FBKA 5JPFA 3QFKA 1V73A 2QFPA 1XM7A 2GJUA 3THOB 5DNYA 3PSOA 3THNA 1U32A 4HD0A 2BCDA 2NYLC 4DSYA 1KBPA 1XZWA
chains in the Genus database with same CATH superfamily
5HPEA 3GVEA 3H61A 3T1IA 1S3NA 1HPUA 1Z2WA 4DHLA 4UT2A 1S70A 2ZBMA 5JPEA 3QFOA 3FGAC 4I5LC 1SU1A 1AUIA 1WARA 2WDDA 4MOYA 3RQZA 4J6OA 2O8AA 1S95A 2Z1AA 4UT3A 5J28A 4MOVA 2A22A 1QHWA 1Z2XA 4H1YP 1FJMA 4TUIA 2DFJA 5INBA 1JK7A 3FLOA 2WDFA 3RL4A 5F3WA 4V0WA 2ZOAA 2WDEA 1T71A 1OIEA 3ICFA 4JA7A 2KKNA 3IB7A 4DT2A 1S3MA 1S3LA 5EQVA 4ORBA 1HO5A 2CV9A 1T70A 3DSDA 3RL3A 4ZX2A 2DXNA 1USHA 4FBWA 4FBQA 3IVEA 3H62B 4ORAA 2BDXA 2WDCA 1UF3A 2O8GA 4OR9A 4YKEA 2XMOA 4JA9A 1G5BA 4FCXA 1S8EA 2YEQA 4V0XA 3H64A 1W24A 3ZTVA 3P71C 4O43A 3IB8A 1WAO1 1OI8A 2Z72A 4H1SA 4H2IA 2DXLA 4LACC 4F0ZA 3QG5C 3IVDA 1OIDA 2NYMC 4LTYA 3H68A 2HYOA 4O5GA 1TCOA 1HP1A 3HVQA 3JYFA 3AUZA 3LL8A 4NZVA 2NXFA 2P6BA 3E0JA 3E7BA 3H66A 4KBPA 1II7A 4IYPC 4B2OA 4KKZA 2AHDA 4ORCA 3DW8C 2IAEC 4H2FA 5GTUA 1IT6A 1NNWA 2BQ8X 3EGHA 3ZU0A 4O24A 3DSCA 1QFCA 4O4KA 3QFNA 1UTEA 4I5NC 3TGHA 3RL5A 2ZO9B 3E7AA 2HYPA 3QFMA 4WWLA 5B8IA 2IE3C 2Q8UA 3AV0A 4TUGA 2QFRA 3H60A 4Q7FA 4IL1A 4MP0A 3V4YA 5JJTA 2JOGA 1M63A 5C1VA 4H2BA 2USHA 3PSNA 1MF8A 2NPPC 3KBPA 2YVTA 4UWQA 4V0VA 3H69A 3CK2A 4LU9A 2R17A 2Z06A 3H67A 4XPNA 3K7WC 3C5WC 4M0VA 2IE4C 3K7VC 3N5UA 2QJCA 4G9JA 4UT3B 4ZVZA 3EGGA 4H2GA 3H63A 5IOHA 2HY1A 3C9FA 4FBKA 5JPFA 3QFKA 1V73A 2QFPA 1XM7A 2GJUA 3THOB 5DNYA 3PSOA 3THNA 1U32A 4HD0A 2BCDA 2NYLC 4DSYA 1KBPA 3D03A 1XZWA
chains in the Genus database with same CATH topology
5HPEA 3GVEA 3H61A 3T1IA 1S3NA 1HPUA 1Z2WA 4DHLA 4UT2A 1S70A 2ZBMA 5JPEA 3QFOA 3FGAC 4I5LC 1SU1A 1AUIA 1WARA 2WDDA 4MOYA 3RQZA 4J6OA 2O8AA 1S95A 2Z1AA 4UT3A 5J28A 4MOVA 2A22A 1QHWA 1Z2XA 4H1YP 1FJMA 4TUIA 2DFJA 5INBA 1JK7A 3FLOA 2WDFA 3RL4A 5F3WA 4V0WA 2ZOAA 2WDEA 1T71A 1OIEA 3ICFA 4JA7A 2KKNA 3IB7A 4DT2A 1S3MA 1S3LA 5EQVA 4ORBA 1HO5A 2CV9A 1T70A 3DSDA 3RL3A 4ZX2A 2DXNA 1USHA 4FBWA 4FBQA 3IVEA 3H62B 4ORAA 2BDXA 2WDCA 1UF3A 2O8GA 4OR9A 4YKEA 2XMOA 4JA9A 1G5BA 4FCXA 1S8EA 2YEQA 4V0XA 3H64A 1W24A 3ZTVA 3P71C 4O43A 3IB8A 1WAO1 1OI8A 2Z72A 4H1SA 4H2IA 2DXLA 4LACC 4F0ZA 3QG5C 3IVDA 1OIDA 2NYMC 4LTYA 3H68A 2HYOA 4O5GA 1TCOA 1HP1A 3HVQA 3JYFA 3AUZA 3LL8A 4NZVA 2NXFA 2P6BA 3E0JA 3E7BA 3H66A 4KBPA 1II7A 4IYPC 4B2OA 4KKZA 2AHDA 4ORCA 3DW8C 2IAEC 4H2FA 5GTUA 1IT6A 1NNWA 2BQ8X 3EGHA 3ZU0A 4O24A 3DSCA 1QFCA 4O4KA 3QFNA 1UTEA 4I5NC 3TGHA 3RL5A 2ZO9B 3E7AA 2HYPA 3QFMA 4WWLA 5B8IA 2IE3C 2Q8UA 3AV0A 4TUGA 2QFRA 3H60A 4Q7FA 4IL1A 4MP0A 3V4YA 5JJTA 2JOGA 1M63A 5C1VA 4H2BA 2USHA 3PSNA 1MF8A 2NPPC 3KBPA 2YVTA 4UWQA 4V0VA 3H69A 3CK2A 4LU9A 2R17A 2Z06A 3H67A 4XPNA 3K7WC 3C5WC 4M0VA 2IE4C 3K7VC 3N5UA 2QJCA 4G9JA 4UT3B 4ZVZA 3EGGA 4H2GA 3H63A 5IOHA 2HY1A 3C9FA 4FBKA 5JPFA 3QFKA 1V73A 2QFPA 1XM7A 2GJUA 3THOB 5DNYA 3PSOA 3THNA 1U32A 4HD0A 2BCDA 2NYLC 4DSYA 1KBPA 3D03A 1XZWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HPE A;  3GVE A;  3H61 A;  3T1I A;  1S3N A;  1HPU A;  1Z2W A;  4DHL A;  4UT2 A;  1S70 A;  2ZBM A;  5JPE A;  3QFO A;  3FGA C;  4I5L C;  1SU1 A;  1AUI A;  1WAR A;  2WDD A;  4MOY A;  3RQZ A;  4J6O A;  2O8A A;  1S95 A;  2Z1A A;  4UT3 A;  5J28 A;  4MOV A;  2A22 A;  1QHW A;  1Z2X A;  4H1Y P;  1FJM A;  4TUI A;  2DFJ A;  5INB A;  1JK7 A;  2WDF A;  3RL4 A;  5F3W A;  4V0W A;  2WDE A;  1T71 A;  1OIE A;  3ICF A;  4JA7 A;  2KKN A;  3IB7 A;  4DT2 A;  1S3M A;  1S3L A;  5EQV A;  4ORB A;  1HO5 A;  2CV9 A;  1T70 A;  3DSD A;  3RL3 A;  4ZX2 A;  1USH A;  4FBW A;  4FBQ A;  3IVE A;  3H62 B;  4ORA A;  2BDX A;  2WDC A;  1UF3 A;  2O8G A;  4OR9 A;  4YKE A;  2XMO A;  4JA9 A;  1G5B A;  4FCX A;  1S8E A;  4V0X A;  3H64 A;  1W24 A;  3ZTV A;  3P71 C;  4O43 A;  3IB8 A;  1WAO 1;  1OI8 A;  2Z72 A;  4H1S A;  4H2I A;  4LAC C;  4F0Z A;  3QG5 C;  3IVD A;  1OID A;  2NYM C;  4LTY A;  3H68 A;  2HYO A;  4O5G A;  1TCO A;  1HP1 A;  3HVQ A;  3JYF A;  3AUZ A;  3LL8 A;  4NZV A;  2NXF A;  2P6B A;  3E7B A;  3H66 A;  4KBP A;  4B2O A;  1II7 A;  4IYP C;  4KKZ A;  2AHD A;  4ORC A;  3DW8 C;  2IAE C;  4H2F A;  5GTU A;  1IT6 A;  1NNW A;  2BQ8 X;  3EGH A;  3ZU0 A;  4O24 A;  3DSC A;  1QFC A;  4O4K A;  3QFN A;  1UTE A;  4I5N C;  3TGH A;  3RL5 A;  3E7A A;  2HYP A;  3QFM A;  4WWL A;  5B8I A;  2IE3 C;  2Q8U A;  3AV0 A;  4TUG A;  2QFR A;  3H60 A;  4Q7F A;  4IL1 A;  4MP0 A;  3V4Y A;  5JJT A;  2JOG A;  1M63 A;  5C1V A;  4H2B A;  2USH A;  3PSN A;  1MF8 A;  2NPP C;  3KBP A;  2YVT A;  4UWQ A;  4V0V A;  3H69 A;  3CK2 A;  4LU9 A;  2R17 A;  2Z06 A;  3H67 A;  4XPN A;  3K7W C;  3C5W C;  4M0V A;  2IE4 C;  3K7V C;  3N5U A;  2QJC A;  4G9J A;  4UT3 B;  4ZVZ A;  3EGG A;  4H2G A;  3H63 A;  5IOH A;  2HY1 A;  3C9F A;  4FBK A;  5JPF A;  3QFK A;  1V73 A;  2QFP A;  1XM7 A;  2GJU A;  3THO B;  5DNY A;  3PSO A;  3THN A;  1U32 A;  4HD0 A;  2BCD A;  2NYL C;  4DSY A;  1KBP A;  1XZW A; 
#chains in the Genus database with same CATH topology
 5HPE A;  3GVE A;  3H61 A;  3T1I A;  1S3N A;  1HPU A;  1Z2W A;  4DHL A;  4UT2 A;  1S70 A;  2ZBM A;  5JPE A;  3QFO A;  3FGA C;  4I5L C;  1SU1 A;  1AUI A;  1WAR A;  2WDD A;  4MOY A;  3RQZ A;  4J6O A;  2O8A A;  1S95 A;  2Z1A A;  4UT3 A;  5J28 A;  4MOV A;  2A22 A;  1QHW A;  1Z2X A;  4H1Y P;  1FJM A;  4TUI A;  2DFJ A;  5INB A;  1JK7 A;  3FLO A;  2WDF A;  3RL4 A;  5F3W A;  4V0W A;  2ZOA A;  2WDE A;  1T71 A;  1OIE A;  3ICF A;  4JA7 A;  2KKN A;  3IB7 A;  4DT2 A;  1S3M A;  1S3L A;  5EQV A;  4ORB A;  1HO5 A;  2CV9 A;  1T70 A;  3DSD A;  3RL3 A;  4ZX2 A;  2DXN A;  1USH A;  4FBW A;  4FBQ A;  3IVE A;  3H62 B;  4ORA A;  2BDX A;  2WDC A;  1UF3 A;  2O8G A;  4OR9 A;  4YKE A;  2XMO A;  4JA9 A;  1G5B A;  4FCX A;  1S8E A;  2YEQ A;  4V0X A;  3H64 A;  1W24 A;  3ZTV A;  3P71 C;  4O43 A;  3IB8 A;  1WAO 1;  1OI8 A;  2Z72 A;  4H1S A;  4H2I A;  2DXL A;  4LAC C;  4F0Z A;  3QG5 C;  3IVD A;  1OID A;  2NYM C;  4LTY A;  3H68 A;  2HYO A;  4O5G A;  1TCO A;  1HP1 A;  3HVQ A;  3JYF A;  3AUZ A;  3LL8 A;  4NZV A;  2NXF A;  2P6B A;  3E0J A;  3E7B A;  3H66 A;  4KBP A;  1II7 A;  4IYP C;  4B2O A;  4KKZ A;  2AHD A;  4ORC A;  3DW8 C;  2IAE C;  4H2F A;  5GTU A;  1IT6 A;  1NNW A;  2BQ8 X;  3EGH A;  3ZU0 A;  4O24 A;  3DSC A;  1QFC A;  4O4K A;  3QFN A;  1UTE A;  4I5N C;  3TGH A;  3RL5 A;  2ZO9 B;  3E7A A;  2HYP A;  3QFM A;  4WWL A;  5B8I A;  2IE3 C;  2Q8U A;  3AV0 A;  4TUG A;  2QFR A;  3H60 A;  4Q7F A;  4IL1 A;  4MP0 A;  3V4Y A;  5JJT A;  2JOG A;  1M63 A;  5C1V A;  4H2B A;  2USH A;  3PSN A;  1MF8 A;  2NPP C;  3KBP A;  2YVT A;  4UWQ A;  4V0V A;  3H69 A;  3CK2 A;  4LU9 A;  2R17 A;  2Z06 A;  3H67 A;  4XPN A;  3K7W C;  3C5W C;  4M0V A;  2IE4 C;  3K7V C;  3N5U A;  2QJC A;  4G9J A;  4UT3 B;  4ZVZ A;  3EGG A;  4H2G A;  3H63 A;  5IOH A;  2HY1 A;  3C9F A;  4FBK A;  5JPF A;  3QFK A;  1V73 A;  2QFP A;  1XM7 A;  2GJU A;  3THO B;  5DNY A;  3PSO A;  3THN A;  1U32 A;  4HD0 A;  2BCD A;  2NYL C;  4DSY A;  1KBP A;  3D03 A;  1XZW A; 
#chains in the Genus database with same CATH homology
 5HPE A;  3GVE A;  3H61 A;  3T1I A;  1S3N A;  1HPU A;  1Z2W A;  4DHL A;  4UT2 A;  1S70 A;  2ZBM A;  5JPE A;  3QFO A;  3FGA C;  4I5L C;  1SU1 A;  1AUI A;  1WAR A;  2WDD A;  4MOY A;  3RQZ A;  4J6O A;  2O8A A;  1S95 A;  2Z1A A;  4UT3 A;  5J28 A;  4MOV A;  2A22 A;  1QHW A;  1Z2X A;  4H1Y P;  1FJM A;  4TUI A;  2DFJ A;  5INB A;  1JK7 A;  3FLO A;  2WDF A;  3RL4 A;  5F3W A;  4V0W A;  2ZOA A;  2WDE A;  1T71 A;  1OIE A;  3ICF A;  4JA7 A;  2KKN A;  3IB7 A;  4DT2 A;  1S3M A;  1S3L A;  5EQV A;  4ORB A;  1HO5 A;  2CV9 A;  1T70 A;  3DSD A;  3RL3 A;  4ZX2 A;  2DXN A;  1USH A;  4FBW A;  4FBQ A;  3IVE A;  3H62 B;  4ORA A;  2BDX A;  2WDC A;  1UF3 A;  2O8G A;  4OR9 A;  4YKE A;  2XMO A;  4JA9 A;  1G5B A;  4FCX A;  1S8E A;  2YEQ A;  4V0X A;  3H64 A;  1W24 A;  3ZTV A;  3P71 C;  4O43 A;  3IB8 A;  1WAO 1;  1OI8 A;  2Z72 A;  4H1S A;  4H2I A;  2DXL A;  4LAC C;  4F0Z A;  3QG5 C;  3IVD A;  1OID A;  2NYM C;  4LTY A;  3H68 A;  2HYO A;  4O5G A;  1TCO A;  1HP1 A;  3HVQ A;  3JYF A;  3AUZ A;  3LL8 A;  4NZV A;  2NXF A;  2P6B A;  3E0J A;  3E7B A;  3H66 A;  4KBP A;  1II7 A;  4IYP C;  4B2O A;  4KKZ A;  2AHD A;  4ORC A;  3DW8 C;  2IAE C;  4H2F A;  5GTU A;  1IT6 A;  1NNW A;  2BQ8 X;  3EGH A;  3ZU0 A;  4O24 A;  3DSC A;  1QFC A;  4O4K A;  3QFN A;  1UTE A;  4I5N C;  3TGH A;  3RL5 A;  2ZO9 B;  3E7A A;  2HYP A;  3QFM A;  4WWL A;  5B8I A;  2IE3 C;  2Q8U A;  3AV0 A;  4TUG A;  2QFR A;  3H60 A;  4Q7F A;  4IL1 A;  4MP0 A;  3V4Y A;  5JJT A;  2JOG A;  1M63 A;  5C1V A;  4H2B A;  2USH A;  3PSN A;  1MF8 A;  2NPP C;  3KBP A;  2YVT A;  4UWQ A;  4V0V A;  3H69 A;  3CK2 A;  4LU9 A;  2R17 A;  2Z06 A;  3H67 A;  4XPN A;  3K7W C;  3C5W C;  4M0V A;  2IE4 C;  3K7V C;  3N5U A;  2QJC A;  4G9J A;  4UT3 B;  4ZVZ A;  3EGG A;  4H2G A;  3H63 A;  5IOH A;  2HY1 A;  3C9F A;  4FBK A;  5JPF A;  3QFK A;  1V73 A;  2QFP A;  1XM7 A;  2GJU A;  3THO B;  5DNY A;  3PSO A;  3THN A;  1U32 A;  4HD0 A;  2BCD A;  2NYL C;  4DSY A;  1KBP A;  3D03 A;  1XZW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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