3THOB

Crystal structure of mre11:rad50 in its atp/adp bound state
Total Genus 111
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
111
sequence length
377
structure length
366
Chain Sequence
MKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNQDWKGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAGREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDSCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIERKSRREIEEVLRESPEEFKEELDKLDYFELFKEYLKKREENHEKLLKILDELLDEVKKS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex.
pubmed doi rcsb
source organism Thermotoga maritima
molecule tags Hydrolase/dna binding protein
molecule keywords Probable DNA double-strand break repair Rad50 ATPase
total genus 111
structure length 366
sequence length 377
ec nomenclature
pdb deposition date 2011-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.160.210 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain DNA double-strand break repair nuclease 3thoB02
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3thoB01
2A22A 3AUZA 1MF8A 3H66A 5JJTA 5DNYA 2BDXA 1UF3A 4H2BA 1S70A 3HVQA 4OR9A 4KKZA 2Q8UA 1Z2XA 4DHLA 5IOHA 2QFPA 3RL3A 1S8EA 2DFJA 1QFCA 1T70A 3FGAC 3H67A 3AV0A 2WDDA 4DSYA 1S95A 3TGHA 4O5GA 2QFRA 4I5LC 4Q7FA 1Z2WA 2CV9A 3ZTVA 4J6OA 2NYLC 1HP1A 2NXFA 3QFNA 2HY1A 4H1YP 1XZWA 2ZBMA 4ZVZA 3H60A 1W24A 4H2GA 3RQZA 4TUGA 2NPPC 1JK7A 1TCOA 3CK2A 3QFOA 4WWLA 3RL4A 5J28A 4V0WA 4FBWA 1M63A 3QFKA 3THNA 4O24A 4MP0A 4ORBA 3DSCA 4UT3A 4UT3B 1T71A 1S3LA 2WDEA 3EGGA 3H62B 3JYFA 4FBQA 3C5WC 1WARA 4H2IA 3GVEA 2WDCA 2BQ8X 4IL1A 5GTUA 4G9JA 1V73A 2YVTA 4HD0A 4V0VA 3K7VC 4H2FA 3N5UA 5C1VA 5JPEA 4I5NC 1WAO1 1NNWA 4JA9A 4LACC 3H64A 5JPFA 3DW8C 1AUIA 1U32A 3RL5A 1FJMA 2R17A 2USHA 3IB7A 5EQVA 2Z1AA 2KKNA 4O4KA 2BCDA 4YKEA 1II7A 3H63A 4O43A 2IE4C 5B8IA 3H68A 2HYOA 1IT6A 3H61A 3C9FA 3DSDA 3ICFA 1KBPA 3KBPA 3PSNA 4KBPA 1UTEA 3IB8A 3E7AA 3IVEA 3IVDA 3V4YA 4ORCA 1S3NA 2XMOA 1XM7A 3LL8A 4V0XA 3PSOA 4JA7A 1OIEA 4M0VA 4MOYA 2Z72A 3QG5C 2IAEC 3EGHA 2JOGA 2HYPA 1HO5A 1S3MA 2IE3C 1OIDA 4UT2A 4LTYA 1QHWA 4F0ZA 2WDFA 2GJUA 3P71C 3THOB 4FBKA 4UWQA 4ZX2A 5F3WA 3E7BA 3ZU0A 4TUIA 2O8AA 4MOVA 5HPEA 1USHA 5INBA 1HPUA 3H69A 1OI8A 4DT2A 4FCXA 2AHDA 3QFMA 4IYPC 4B2OA 1G5BA 2O8GA 2Z06A 4ORAA 4XPNA 4H1SA 2P6BA 1SU1A 2QJCA 3K7WC 3T1IA 4LU9A 2NYMC 4NZVA
chains in the Genus database with same CATH superfamily
3IWCA 2WBUA 4K0KE 1BB8A 2DRPA 4R2RA 2YSOA 3ADLA 2YTJA 2EOQA 3HVQA 1IBLE 4F9CB 1WJPA 1SFEA 1S8EA 3H67A 1KYQA 4BS9A 3J80C 1J5EE 2RTXA 3TGHA 1WXRA 4Q7FA 1Z2WA 5IT9C 4J6OA 4LF7E 3QFNA 1HP1A 2NXFA 1ZBTA 2HY1A 2B3TB 1XZWA 4H1YP 5IWAE 1WHNA 4J8ZA 2EN4A 1W24A 2LTRA 2YEQA 2EN2A 1JK7A 4WWLA 4FBWA 2UXDE 2V87A 2JYAA 2DSYA 2FGGA 1XNRE 2R1FA 2E72A 4R2AA 2V86A 1IMUA 1S3LA 2EP3A 1T71A 2DXLA 3H62B 4FBQA 4DV2E 1X48A 3C5WC 2L3CA 2EPLX 2LJHA 4F9BB 2L8TA 5AC4A 4B3RE 1ZR9A 2L2MA 3ZOQB 2VF1A 4V0VA 5C1VA 3N5UA 4JI8E 2EOIA 2EPOA 1NNWA 4JA9A 2CTDA 4LACC 1X6FA 3DW8C 4DV1E 2DIXA 1TN9A 2GHFA 2NA2A 2YT4A 1FJMA 2R17A 4DV0E 2EMAA 2M7QA 2USHA 2EOEA 2Z1AA 1IBME 3EPKA 2BCDA 2EQ1A 1II7A 5TSEA 4O43A 2IE4C 5B8IA 4JI6E 2LVHA 4DR1E 4WX9A 3DSDA 3KZZA 3ICFA 2EOJA 3F6HA 4WSPA 3KBPA 1X49A 2EPAA 4OOGC 1ZBQA 2LUQA 2CT1A 1AH5A 2JOXA 1PKPA 4WYQB 1XNQE 2PRTA 2EOSA 4B3ME 2NUFA 2IHR1 2EPPA 4JI4E 4FK5C 4M0VA 2EM2A 4ZYDA 5A6AA 5KL4A 2EN6A 1A1KA 1X3CA 2UXCE 2EOMA 3C6KA 2BB8A 1YYOA 2YPNA 2VQFE 1XMQE 2YZTA 5LL6R 4DR7E 4F0ZA 3J7AG 2WDFA 2HHHE 3P71C 4UWQA 4HTGA 2YTEA 4GZNC 4N4RB 1BBOA 2UUBE 3OMLA 3JU0A 4DV3E 3ADIA 2BBGA 3K6QA 2ENAA 2EJ4A 2EPMX 4XPNA 2B7TA 4H1SA 4NHRA 3K7WC 1IBKE 2NYMC 1YFHA 5IXMB 3C4TA 2EM3A 3P1XA 5DNYA 2YRMA 2VQEE 2EM8A 1MF8A 2BDXA 1IQSA 2V8QB 4GEQB 5A2QC 1YZ9A 1YUJA 2JY9A 2FV4B 1Z2XA 2QFPA 2LUPB 4LF8E 2DFJA 3FGAC 2JPAA 4KZSA 1S95A 2EMCA 4O5GA 2QFRA 1A1IA 2V85A 4NXME 3EPJA 2YTIA 2EMWA 4HEIA 2ODRC 4DR5E 2EM5A 2WCC3 2V88A 3T1YE 3C4BA 2EM7A 4LFAE 2EL5A 3FLOA 1UHZA 3HXLA 2NPPC 4BC9A 2DMYA 3CK2A 4JI5E 5J28A 5KL3A 1M63A 2HJJA 2EPRA 2WBTA 2M9AA 2EL4A 4UT3B 1DQ3A 2UU9E 4DV7E 2LO3A 1N32E 2ODRD 1HR0E 2YTNA 4H2IA 3GVEA 2JR1A 2BQ8X 4GKKE 2WDCA 5GTUA 4JI0E 2EOYA 2YVTA 2N3HA 5IV8B 5JPEA 5CFFE 3VYXA 2RS6A 4F6NA 3KWRA 1MGTA 2YRKA 5LLQA 3RL5A 4BHBA 2I13A 2LE2A 4L5NC 3IB7A 4LFBE 2EPUA 1NEIA 4JI3E 3LMLA 2RQLA 4KWYA 1UBDC 4LF4E 3JAMC 3ECRA 4KHPE 2HYOA 2NABA 2L92A 3C9FA 2DLQA 1Z1BA 3PSNA 1G2FC 4KBPA 2ZO9B 1N33E 1YSAC 2B7VA 3DJWA 4R2PA 4V0XA 3PSOA 3JTZA 2MDRA 4R2CA 4MOYA 2CSHA 4M2ZA 4DUYE 2ZOAA 2HYPA 1ZAAC 2L2NA 1HO5A 3E0JA 3H09A 5BR8E 2V89A 4L8NA 2LBSB 3MHSC 2GJUA 2EMIA 2YU8A 4FBKA 3BIDA 3E7BA 2O8AA 1RMDA 1A1HA 5HPEA 1X5WA 4BMJA 2GPIA 3HTXA 2YTQA 2LRSA 3TQMA 3M99B 4OX9E 1J26A 2J7JA 4DV5E 4FCXA 3MSWA 2AHDA 2EMFA 5AE1A 3QFMA 2NUGA 2H36X 1GQEA 2LMZA 1G2DC 2RSIA 2Z06A 4JI7E 2NUEA 1FKAE 2F8BA 2EQ3A 4WXDA 5KL7A 2MKDA 5ADZA 2EOHA 4X9JA 4R2EA 1TF6A 2R76A 2EWLA 2N3GA 1S70A 4H2BA 4OR9A 3EQ1A 1YYWA 3HPSA 4Q35B 4WFTA 2DMIA 4WPYA 1PJSA 1DGCA 2EN1A 3AV0A 4DSYA 2MC5A 2EN8A 5AC5A 3BBGA 2CV9A 4WSGA 2ZBMA 4NXNE 2JOBA 2E1MA 4DR3E 1PJTA 3RQZA 1HNXE 2MKNA 1TCOA 4MLQA 2EPKX 2EMBA 3QFKA 5AE3A 2EMLA 2EPCA 4DR2E 4MP0A 3DSCA 4UT3A 4X65E 2I9IA 2CPNA 3FIGA 3MHHC 1LLMC 2DGCA 1DI2A 2N8XA 4M30A 2WDEA 3EGGA 2ELYA 2YTOA 3DF6A 1N3GA 2L6MA 1YUIA 1IQOA 5LMNE 4IL1A 1MEYC 4F2JC 4G9JA 4B3SE 3UK3C 3K7VC 4DV6E 2EM0A 4YY3E 4GKJE 4I5NC 1UILA 4LFCE 3EPHA 1T4OA 1AUIA 1U32A 1WHQA 4X62E 2LT7A 4RHBB 1N36E 4LF5E 1X6HA 3HQ1A 1WRJA 2HC5A 2MDGA 1JK2A 2KKNA 4IS1C 1T4LB 2RSMA 2YRHA 3H68A 2UUCE 2EMHA 2VRDA 1IT6A 3H61A 4BHCA 1A1GA 2EM9A 3HPZA 2MC6A 4P78A 1KBPA 2A25A 3IB8A 4X66E 2KHXA 3E7AA 2L2KB 2YTPA 1GTKA 1O0WA 3IVDA 3V4YA 4F6MA 2F4VE 2KOUA 1S3NA 3LL8A 5AASA 2LCEA 4MLVA 1QU6A 1OIEA 3ADJA 1A1JA 2IAEC 2JOGA 3KZYA 5LMUE 1HNWE 4I8OA 4JV5E 1N34E 4UT2A 4LTYA 4P7DA 1HNZE 2LV2A 1TF3A 2EPNA 1RC7A 1EH6A 2JXPA 3THOB 1YYKA 3VYYA 1BBGA 2EORA 1T38A 5KL2A 4YHHE 1USHA 2YU5A 1HPUA 2B9DA 2DLKA 4DMIA 5FLXC 4DR4E 2V83A 2ZM6E 4DUZE 4B2OA 2HGHA 1G5BA 2ENHA 2EMKA 1PJQA 2EPZA 1I94E 2O8GA 3D03A 1YPNA 2LTSA 4X64E 2YTDA 4ORAA 1EH8A 1SU1A 2QJCA 2L3JA 4LF9E 4NZVA 5JPFA 4JI1E 3AUZA 4ZYGA 2A22A 1XMOE 3H66A 5JJTA 1UF3A 2EM4A 2GLIA 3T1HE 1FJGE 1UN6B 3VK6A 2M1SA 2DB2A 3BGHA 4KKZA 2Q8UA 4DHLA 5IOHA 3RL3A 1QFCA 1T70A 3IWBA 2L33A 2WDDA 3J7Yp 1QNTA 4I5LC 4DKKA 4R2QA 3ZTVA 2EM6A 3F6GA 3RMPA 2NYLC 2ENCA 4ZYEA 4JYAE 4ZVZA 3H60A 4H2GA 4TUGA 1X6EA 5T6JA 1AAYA 3RL4A 3QFOA 4V0WA 5AE2A 3J81C 3ADGA 2YTGA 5KL6A 1X47A 3THNA 4O24A 4ORBA 4WXCA 1RQ0A 4ZYHA 3JYFA 1P47A 4DR6E 1WARA 1T39A 1GZ6A 4M9VC 2K4VA 2EMZA 2ELZA 3VHTB 2EOXA 1V73A 2WZOA 2EN7A 4HD0A 2LJUA 4H2FA 2KONA 1WAO1 1L4SA 4F9AB 2UXBE 3BF2A 3H64A 3IWDA 4BC7A 4R03A 1SR9A 2DXNA 2JVAA 5A6JA 5EQVA 2EE8A 4O4KA 2G7HA 4X8WA 4YKEA 5A6BD 3C6MA 3H63A 1T4NA 4LF6E 2YWQA 4B3TE 4JI2E 1KJKA 2EOZA 1UTEA 2EMYA 4R2DA 4BBYA 1JK1A 5A6KA 1F2IG 1EKZA 3IVEA 2RS7A 5A6BA 2WBSA 2E5LE 4ORCA 2XMOA 1XM7A 4R2SA 2YTFA 4JA7A 2EPXA 2K7IA 3LLHA 2VE7C 2Z72A 2ADRA 3QG5C 1A1FA 2EMXA 1NCSA 3EGHA 2EOOA 2EQ0A 1S3MA 2M4IA 2IE3C 1OIDA 2EL6A 1QHWA 4R8OA 2EOFA 2D9HA 2UUAE 4AQYE 5KL5A 5F3WA 4IJDA 4ZX2A 2FTXB 3ZU0A 4TUIA 5A69A 4MOVA 4RH8A 5INBA 3OTOE 3H69A 4BCAA 4DV4E 4Q28A 1OI8A 1PDAA 2EMGA 1EH7A 4DT2A 2RPCA 2YSPA 1A1LA 2EZ6A 4IYPC 2EN3A 3L00A 3EPLA 1B69A 2JP9A 1ZU1A 2JWOA 1STUA 2P6BA 3T1IA 4LU9A 4F54A
chains in the Genus database with same CATH topology
2A22A 3AUZA 1MF8A 3H66A 5JJTA 5DNYA 2BDXA 1UF3A 4H2BA 1S70A 3HVQA 4OR9A 4KKZA 2Q8UA 1Z2XA 4DHLA 5IOHA 2QFPA 3RL3A 1S8EA 2DFJA 1QFCA 1T70A 3FGAC 3H67A 3AV0A 2WDDA 4DSYA 1S95A 3TGHA 4O5GA 2QFRA 4I5LC 4Q7FA 1Z2WA 2CV9A 3ZTVA 4J6OA 2NYLC 1HP1A 2NXFA 3QFNA 2HY1A 4H1YP 1XZWA 2ZBMA 4ZVZA 3H60A 1W24A 4H2GA 3FLOA 2YEQA 3RQZA 4TUGA 2NPPC 1JK7A 1TCOA 3CK2A 3QFOA 4WWLA 3RL4A 5J28A 4V0WA 4FBWA 1M63A 3QFKA 3THNA 4O24A 4MP0A 4ORBA 3DSCA 4UT3A 4UT3B 1T71A 1S3LA 2DXLA 2WDEA 3EGGA 3H62B 3JYFA 4FBQA 3C5WC 1WARA 4H2IA 3GVEA 2WDCA 2BQ8X 4IL1A 5GTUA 4G9JA 1V73A 2YVTA 4HD0A 4V0VA 3K7VC 4H2FA 3N5UA 5C1VA 5JPEA 4I5NC 1WAO1 1NNWA 4JA9A 4LACC 3H64A 5JPFA 3DW8C 1AUIA 1U32A 3RL5A 1FJMA 2R17A 2USHA 2DXNA 3IB7A 5EQVA 2Z1AA 2KKNA 4O4KA 2BCDA 4YKEA 1II7A 3H63A 4O43A 2IE4C 5B8IA 3H68A 2HYOA 1IT6A 3H61A 3C9FA 3DSDA 3ICFA 1KBPA 3KBPA 3PSNA 4KBPA 1UTEA 2ZO9B 3IB8A 3E7AA 3IVEA 3IVDA 3V4YA 4ORCA 1S3NA 2XMOA 1XM7A 3LL8A 4V0XA 3PSOA 4JA7A 1OIEA 4M0VA 4MOYA 2Z72A 3QG5C 2IAEC 3EGHA 2JOGA 2ZOAA 2HYPA 1HO5A 1S3MA 3E0JA 2IE3C 1OIDA 4UT2A 4LTYA 1QHWA 4F0ZA 2WDFA 2GJUA 3P71C 3THOB 4FBKA 4UWQA 4ZX2A 5F3WA 3E7BA 3ZU0A 4TUIA 2O8AA 4MOVA 5HPEA 1USHA 5INBA 1HPUA 3H69A 1OI8A 4DT2A 4FCXA 2AHDA 3QFMA 4IYPC 4B2OA 1G5BA 2O8GA 2Z06A 3D03A 4ORAA 4XPNA 4H1SA 2P6BA 1SU1A 2QJCA 3K7WC 3T1IA 4LU9A 2NYMC 4NZVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A22 A;  3AUZ A;  1MF8 A;  3H66 A;  5JJT A;  5DNY A;  2BDX A;  1UF3 A;  4H2B A;  1S70 A;  3HVQ A;  4OR9 A;  4KKZ A;  2Q8U A;  1Z2X A;  4DHL A;  5IOH A;  2QFP A;  3RL3 A;  1S8E A;  2DFJ A;  1QFC A;  1T70 A;  3FGA C;  3H67 A;  3AV0 A;  2WDD A;  4DSY A;  1S95 A;  3TGH A;  4O5G A;  2QFR A;  4I5L C;  4Q7F A;  1Z2W A;  2CV9 A;  3ZTV A;  4J6O A;  2NYL C;  1HP1 A;  2NXF A;  3QFN A;  2HY1 A;  4H1Y P;  1XZW A;  2ZBM A;  4ZVZ A;  3H60 A;  1W24 A;  4H2G A;  3RQZ A;  4TUG A;  2NPP C;  1JK7 A;  1TCO A;  3CK2 A;  3QFO A;  4WWL A;  3RL4 A;  5J28 A;  4V0W A;  4FBW A;  1M63 A;  3QFK A;  3THN A;  4O24 A;  4MP0 A;  4ORB A;  3DSC A;  4UT3 A;  4UT3 B;  1T71 A;  1S3L A;  2WDE A;  3EGG A;  3H62 B;  3JYF A;  4FBQ A;  3C5W C;  1WAR A;  4H2I A;  3GVE A;  2WDC A;  2BQ8 X;  4IL1 A;  5GTU A;  4G9J A;  1V73 A;  2YVT A;  4HD0 A;  4V0V A;  3K7V C;  4H2F A;  3N5U A;  5C1V A;  5JPE A;  4I5N C;  1WAO 1;  1NNW A;  4JA9 A;  4LAC C;  3H64 A;  5JPF A;  3DW8 C;  1AUI A;  1U32 A;  3RL5 A;  1FJM A;  2R17 A;  2USH A;  3IB7 A;  5EQV A;  2Z1A A;  2KKN A;  4O4K A;  2BCD A;  4YKE A;  1II7 A;  3H63 A;  4O43 A;  2IE4 C;  5B8I A;  3H68 A;  2HYO A;  1IT6 A;  3H61 A;  3C9F A;  3DSD A;  3ICF A;  1KBP A;  3KBP A;  3PSN A;  4KBP A;  1UTE A;  3IB8 A;  3E7A A;  3IVE A;  3IVD A;  3V4Y A;  4ORC A;  1S3N A;  2XMO A;  1XM7 A;  3LL8 A;  4V0X A;  3PSO A;  4JA7 A;  1OIE A;  4M0V A;  4MOY A;  2Z72 A;  3QG5 C;  2IAE C;  3EGH A;  2JOG A;  2HYP A;  1HO5 A;  1S3M A;  2IE3 C;  1OID A;  4UT2 A;  4LTY A;  1QHW A;  4F0Z A;  2WDF A;  2GJU A;  3P71 C;  3THO B;  4FBK A;  4UWQ A;  4ZX2 A;  5F3W A;  3E7B A;  3ZU0 A;  4TUI A;  2O8A A;  4MOV A;  5HPE A;  1USH A;  5INB A;  1HPU A;  3H69 A;  1OI8 A;  4DT2 A;  4FCX A;  2AHD A;  3QFM A;  4IYP C;  4B2O A;  1G5B A;  2O8G A;  2Z06 A;  4ORA A;  4XPN A;  4H1S A;  2P6B A;  1SU1 A;  2QJC A;  3K7W C;  3T1I A;  4LU9 A;  2NYM C;  4NZV A; 
#chains in the Genus database with same CATH topology
 3IWC A;  2WBU A;  4K0K E;  1BB8 A;  2DRP A;  4R2R A;  2YSO A;  3ADL A;  2YTJ A;  2EOQ A;  3HVQ A;  1IBL E;  4F9C B;  1WJP A;  1SFE A;  1S8E A;  3H67 A;  1KYQ A;  4BS9 A;  3J80 C;  1J5E E;  2RTX A;  3TGH A;  1WXR A;  4Q7F A;  1Z2W A;  5IT9 C;  4J6O A;  4LF7 E;  3QFN A;  1HP1 A;  2NXF A;  1ZBT A;  2HY1 A;  2B3T B;  1XZW A;  4H1Y P;  5IWA E;  1WHN A;  4J8Z A;  2EN4 A;  1W24 A;  2LTR A;  2YEQ A;  2EN2 A;  1JK7 A;  4WWL A;  4FBW A;  2UXD E;  2V87 A;  2JYA A;  2DSY A;  2FGG A;  1XNR E;  2R1F A;  2E72 A;  4R2A A;  2V86 A;  1IMU A;  1S3L A;  2EP3 A;  1T71 A;  2DXL A;  3H62 B;  4FBQ A;  4DV2 E;  1X48 A;  3C5W C;  2L3C A;  2EPL X;  2LJH A;  4F9B B;  2L8T A;  5AC4 A;  4B3R E;  1ZR9 A;  2L2M A;  3ZOQ B;  2VF1 A;  4V0V A;  5C1V A;  3N5U A;  4JI8 E;  2EOI A;  2EPO A;  1NNW A;  4JA9 A;  2CTD A;  4LAC C;  1X6F A;  3DW8 C;  4DV1 E;  2DIX A;  1TN9 A;  2GHF A;  2NA2 A;  2YT4 A;  1FJM A;  2R17 A;  4DV0 E;  2EMA A;  2M7Q A;  2USH A;  2EOE A;  2Z1A A;  1IBM E;  3EPK A;  2BCD A;  2EQ1 A;  1II7 A;  5TSE A;  4O43 A;  2IE4 C;  5B8I A;  4JI6 E;  2LVH A;  4DR1 E;  4WX9 A;  3DSD A;  3KZZ A;  3ICF A;  2EOJ A;  3F6H A;  4WSP A;  3KBP A;  1X49 A;  2EPA A;  4OOG C;  1ZBQ A;  2LUQ A;  2CT1 A;  1AH5 A;  2JOX A;  1PKP A;  4WYQ B;  1XNQ E;  2PRT A;  2EOS A;  4B3M E;  2NUF A;  2IHR 1;  2EPP A;  4JI4 E;  4FK5 C;  4M0V A;  2EM2 A;  4ZYD A;  5A6A A;  5KL4 A;  2EN6 A;  1A1K A;  1X3C A;  2UXC E;  2EOM A;  3C6K A;  2BB8 A;  1YYO A;  2YPN A;  2VQF E;  1XMQ E;  2YZT A;  5LL6 R;  4DR7 E;  4F0Z A;  3J7A G;  2WDF A;  2HHH E;  3P71 C;  4UWQ A;  4HTG A;  2YTE A;  4GZN C;  4N4R B;  1BBO A;  2UUB E;  3OML A;  3JU0 A;  4DV3 E;  3ADI A;  2BBG A;  3K6Q A;  2ENA A;  2EJ4 A;  2EPM X;  4XPN A;  2B7T A;  4H1S A;  4NHR A;  3K7W C;  1IBK E;  2NYM C;  1YFH A;  5IXM B;  3C4T A;  2EM3 A;  3P1X A;  5DNY A;  2YRM A;  2VQE E;  2EM8 A;  1MF8 A;  2BDX A;  1IQS A;  2V8Q B;  4GEQ B;  5A2Q C;  1YZ9 A;  1YUJ A;  2JY9 A;  2FV4 B;  1Z2X A;  2QFP A;  2LUP B;  4LF8 E;  2DFJ A;  3FGA C;  2JPA A;  4KZS A;  1S95 A;  2EMC A;  4O5G A;  2QFR A;  1A1I A;  2V85 A;  4NXM E;  3EPJ A;  2YTI A;  2EMW A;  4HEI A;  2ODR C;  4DR5 E;  2EM5 A;  2WCC 3;  2V88 A;  3T1Y E;  3C4B A;  2EM7 A;  4LFA E;  2EL5 A;  3FLO A;  1UHZ A;  3HXL A;  2NPP C;  4BC9 A;  2DMY A;  3CK2 A;  4JI5 E;  5J28 A;  5KL3 A;  1M63 A;  2HJJ A;  2EPR A;  2WBT A;  2M9A A;  2EL4 A;  4UT3 B;  1DQ3 A;  2UU9 E;  4DV7 E;  2LO3 A;  1N32 E;  2ODR D;  1HR0 E;  2YTN A;  4H2I A;  3GVE A;  2JR1 A;  2BQ8 X;  4GKK E;  2WDC A;  5GTU A;  4JI0 E;  2EOY A;  2YVT A;  2N3H A;  5IV8 B;  5JPE A;  5CFF E;  3VYX A;  2RS6 A;  4F6N A;  3KWR A;  1MGT A;  2YRK A;  5LLQ A;  3RL5 A;  4BHB A;  2I13 A;  2LE2 A;  4L5N C;  3IB7 A;  4LFB E;  2EPU A;  1NEI A;  4JI3 E;  3LML A;  2RQL A;  4KWY A;  1UBD C;  4LF4 E;  3JAM C;  3ECR A;  4KHP E;  2HYO A;  2NAB A;  2L92 A;  3C9F A;  2DLQ A;  1Z1B A;  3PSN A;  1G2F C;  4KBP A;  2ZO9 B;  1N33 E;  1YSA C;  2B7V A;  3DJW A;  4R2P A;  4V0X A;  3PSO A;  3JTZ A;  2MDR A;  4R2C A;  4MOY A;  2CSH A;  4M2Z A;  4DUY E;  2ZOA A;  2HYP A;  1ZAA C;  2L2N A;  1HO5 A;  3E0J A;  3H09 A;  5BR8 E;  2V89 A;  4L8N A;  2LBS B;  3MHS C;  2GJU A;  2EMI A;  2YU8 A;  4FBK A;  3BID A;  3E7B A;  2O8A A;  1RMD A;  1A1H A;  5HPE A;  1X5W A;  4BMJ A;  2GPI A;  3HTX A;  2YTQ A;  2LRS A;  3TQM A;  3M99 B;  4OX9 E;  1J26 A;  2J7J A;  4DV5 E;  4FCX A;  3MSW A;  2AHD A;  2EMF A;  5AE1 A;  3QFM A;  2NUG A;  2H36 X;  1GQE A;  2LMZ A;  1G2D C;  2RSI A;  2Z06 A;  4JI7 E;  2NUE A;  1FKA E;  2F8B A;  2EQ3 A;  4WXD A;  5KL7 A;  2MKD A;  5ADZ A;  2EOH A;  4X9J A;  4R2E A;  1TF6 A;  2R76 A;  2EWL A;  2N3G A;  1S70 A;  4H2B A;  4OR9 A;  3EQ1 A;  1YYW A;  3HPS A;  4Q35 B;  4WFT A;  2DMI A;  4WPY A;  1PJS A;  1DGC A;  2EN1 A;  3AV0 A;  4DSY A;  2MC5 A;  2EN8 A;  5AC5 A;  3BBG A;  2CV9 A;  4WSG A;  2ZBM A;  4NXN E;  2JOB A;  2E1M A;  4DR3 E;  1PJT A;  3RQZ A;  1HNX E;  2MKN A;  1TCO A;  4MLQ A;  2EPK X;  2EMB A;  3QFK A;  5AE3 A;  2EML A;  2EPC A;  4DR2 E;  4MP0 A;  3DSC A;  4UT3 A;  4X65 E;  2I9I A;  2CPN A;  3FIG A;  3MHH C;  1LLM C;  2DGC A;  1DI2 A;  2N8X A;  4M30 A;  2WDE A;  3EGG A;  2ELY A;  2YTO A;  3DF6 A;  1N3G A;  2L6M A;  1YUI A;  1IQO A;  5LMN E;  4IL1 A;  1MEY C;  4F2J C;  4G9J A;  4B3S E;  3UK3 C;  3K7V C;  4DV6 E;  2EM0 A;  4YY3 E;  4GKJ E;  4I5N C;  1UIL A;  4LFC E;  3EPH A;  1T4O A;  1AUI A;  1U32 A;  1WHQ A;  4X62 E;  2LT7 A;  4RHB B;  1N36 E;  4LF5 E;  1X6H A;  3HQ1 A;  1WRJ A;  2HC5 A;  2MDG A;  1JK2 A;  2KKN A;  4IS1 C;  1T4L B;  2RSM A;  2YRH A;  3H68 A;  2UUC E;  2EMH A;  2VRD A;  1IT6 A;  3H61 A;  4BHC A;  1A1G A;  2EM9 A;  3HPZ A;  2MC6 A;  4P78 A;  1KBP A;  2A25 A;  3IB8 A;  4X66 E;  2KHX A;  3E7A A;  2L2K B;  2YTP A;  1GTK A;  1O0W A;  3IVD A;  3V4Y A;  4F6M A;  2F4V E;  2KOU A;  1S3N A;  3LL8 A;  5AAS A;  2LCE A;  4MLV A;  1QU6 A;  1OIE A;  3ADJ A;  1A1J A;  2IAE C;  2JOG A;  3KZY A;  5LMU E;  1HNW E;  4I8O A;  4JV5 E;  1N34 E;  4UT2 A;  4LTY A;  4P7D A;  1HNZ E;  2LV2 A;  1TF3 A;  2EPN A;  1RC7 A;  1EH6 A;  2JXP A;  3THO B;  1YYK A;  3VYY A;  1BBG A;  2EOR A;  1T38 A;  5KL2 A;  4YHH E;  1USH A;  2YU5 A;  1HPU A;  2B9D A;  2DLK A;  4DMI A;  5FLX C;  4DR4 E;  2V83 A;  2ZM6 E;  4DUZ E;  4B2O A;  2HGH A;  1G5B A;  2ENH A;  2EMK A;  1PJQ A;  2EPZ A;  1I94 E;  2O8G A;  3D03 A;  1YPN A;  2LTS A;  4X64 E;  2YTD A;  4ORA A;  1EH8 A;  1SU1 A;  2QJC A;  2L3J A;  4LF9 E;  4NZV A;  5JPF A;  4JI1 E;  3AUZ A;  4ZYG A;  2A22 A;  1XMO E;  3H66 A;  5JJT A;  1UF3 A;  2EM4 A;  2GLI A;  3T1H E;  1FJG E;  1UN6 B;  3VK6 A;  2M1S A;  2DB2 A;  3BGH A;  4KKZ A;  2Q8U A;  4DHL A;  5IOH A;  3RL3 A;  1QFC A;  1T70 A;  3IWB A;  2L33 A;  2WDD A;  3J7Y p;  1QNT A;  4I5L C;  4DKK A;  4R2Q A;  3ZTV A;  2EM6 A;  3F6G A;  3RMP A;  2NYL C;  2ENC A;  4ZYE A;  4JYA E;  4ZVZ A;  3H60 A;  4H2G A;  4TUG A;  1X6E A;  5T6J A;  1AAY A;  3RL4 A;  3QFO A;  4V0W A;  5AE2 A;  3J81 C;  3ADG A;  2YTG A;  5KL6 A;  1X47 A;  3THN A;  4O24 A;  4ORB A;  4WXC A;  1RQ0 A;  4ZYH A;  3JYF A;  1P47 A;  4DR6 E;  1WAR A;  1T39 A;  1GZ6 A;  4M9V C;  2K4V A;  2EMZ A;  2ELZ A;  3VHT B;  2EOX A;  1V73 A;  2WZO A;  2EN7 A;  4HD0 A;  2LJU A;  4H2F A;  2KON A;  1WAO 1;  1L4S A;  4F9A B;  2UXB E;  3BF2 A;  3H64 A;  3IWD A;  4BC7 A;  4R03 A;  1SR9 A;  2DXN A;  2JVA A;  5A6J A;  5EQV A;  2EE8 A;  4O4K A;  2G7H A;  4X8W A;  4YKE A;  5A6B D;  3C6M A;  3H63 A;  1T4N A;  4LF6 E;  2YWQ A;  4B3T E;  4JI2 E;  1KJK A;  2EOZ A;  1UTE A;  2EMY A;  4R2D A;  4BBY A;  1JK1 A;  5A6K A;  1F2I G;  1EKZ A;  3IVE A;  2RS7 A;  5A6B A;  2WBS A;  2E5L E;  4ORC A;  2XMO A;  1XM7 A;  4R2S A;  2YTF A;  4JA7 A;  2EPX A;  2K7I A;  3LLH A;  2VE7 C;  2Z72 A;  2ADR A;  3QG5 C;  1A1F A;  2EMX A;  1NCS A;  3EGH A;  2EOO A;  2EQ0 A;  1S3M A;  2M4I A;  2IE3 C;  1OID A;  2EL6 A;  1QHW A;  4R8O A;  2EOF A;  2D9H A;  2UUA E;  4AQY E;  5KL5 A;  5F3W A;  4IJD A;  4ZX2 A;  2FTX B;  3ZU0 A;  4TUI A;  5A69 A;  4MOV A;  4RH8 A;  5INB A;  3OTO E;  3H69 A;  4BCA A;  4DV4 E;  4Q28 A;  1OI8 A;  1PDA A;  2EMG A;  1EH7 A;  4DT2 A;  2RPC A;  2YSP A;  1A1L A;  2EZ6 A;  4IYP C;  2EN3 A;  3L00 A;  3EPL A;  1B69 A;  2JP9 A;  1ZU1 A;  2JWO A;  1STU A;  2P6B A;  3T1I A;  4LU9 A;  4F54 A; 
#chains in the Genus database with same CATH homology
 2A22 A;  3AUZ A;  1MF8 A;  3H66 A;  5JJT A;  5DNY A;  2BDX A;  1UF3 A;  4H2B A;  1S70 A;  3HVQ A;  4OR9 A;  4KKZ A;  2Q8U A;  1Z2X A;  4DHL A;  5IOH A;  2QFP A;  3RL3 A;  1S8E A;  2DFJ A;  1QFC A;  1T70 A;  3FGA C;  3H67 A;  3AV0 A;  2WDD A;  4DSY A;  1S95 A;  3TGH A;  4O5G A;  2QFR A;  4I5L C;  4Q7F A;  1Z2W A;  2CV9 A;  3ZTV A;  4J6O A;  2NYL C;  1HP1 A;  2NXF A;  3QFN A;  2HY1 A;  4H1Y P;  1XZW A;  2ZBM A;  4ZVZ A;  3H60 A;  1W24 A;  4H2G A;  3FLO A;  2YEQ A;  3RQZ A;  4TUG A;  2NPP C;  1JK7 A;  1TCO A;  3CK2 A;  3QFO A;  4WWL A;  3RL4 A;  5J28 A;  4V0W A;  4FBW A;  1M63 A;  3QFK A;  3THN A;  4O24 A;  4MP0 A;  4ORB A;  3DSC A;  4UT3 A;  4UT3 B;  1T71 A;  1S3L A;  2DXL A;  2WDE A;  3EGG A;  3H62 B;  3JYF A;  4FBQ A;  3C5W C;  1WAR A;  4H2I A;  3GVE A;  2WDC A;  2BQ8 X;  4IL1 A;  5GTU A;  4G9J A;  1V73 A;  2YVT A;  4HD0 A;  4V0V A;  3K7V C;  4H2F A;  3N5U A;  5C1V A;  5JPE A;  4I5N C;  1WAO 1;  1NNW A;  4JA9 A;  4LAC C;  3H64 A;  5JPF A;  3DW8 C;  1AUI A;  1U32 A;  3RL5 A;  1FJM A;  2R17 A;  2USH A;  2DXN A;  3IB7 A;  5EQV A;  2Z1A A;  2KKN A;  4O4K A;  2BCD A;  4YKE A;  1II7 A;  3H63 A;  4O43 A;  2IE4 C;  5B8I A;  3H68 A;  2HYO A;  1IT6 A;  3H61 A;  3C9F A;  3DSD A;  3ICF A;  1KBP A;  3KBP A;  3PSN A;  4KBP A;  1UTE A;  2ZO9 B;  3IB8 A;  3E7A A;  3IVE A;  3IVD A;  3V4Y A;  4ORC A;  1S3N A;  2XMO A;  1XM7 A;  3LL8 A;  4V0X A;  3PSO A;  4JA7 A;  1OIE A;  4M0V A;  4MOY A;  2Z72 A;  3QG5 C;  2IAE C;  3EGH A;  2JOG A;  2ZOA A;  2HYP A;  1HO5 A;  1S3M A;  3E0J A;  2IE3 C;  1OID A;  4UT2 A;  4LTY A;  1QHW A;  4F0Z A;  2WDF A;  2GJU A;  3P71 C;  3THO B;  4FBK A;  4UWQ A;  4ZX2 A;  5F3W A;  3E7B A;  3ZU0 A;  4TUI A;  2O8A A;  4MOV A;  5HPE A;  1USH A;  5INB A;  1HPU A;  3H69 A;  1OI8 A;  4DT2 A;  4FCX A;  2AHD A;  3QFM A;  4IYP C;  4B2O A;  1G5B A;  2O8G A;  2Z06 A;  3D03 A;  4ORA A;  4XPN A;  4H1S A;  2P6B A;  1SU1 A;  2QJC A;  3K7W C;  3T1I A;  4LU9 A;  2NYM C;  4NZV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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