1I50L

Rna polymerase ii crystal form ii at 2.8 a resolution
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2001-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 1i50L00
1I3QL 1TWHL 5FJ8L 3S1ML 2E2JL 5FLML 5IYDL 3S1QL 2B63L 4C3HL 2JA7L 3M4OL 3S2DL 5IP9L 4A3LL 3GTKL 4BY1L 3S1NL 4A3ML 2YU9L 1K83L 3HOYL 5M5XL 3S14L 3RZOL 3K7AL 1TWAL 5IYCL 1R9TL 3I4NL 2R7ZL 5IP7L 3H0GL 5M3ML 1WCML 3HOXL 3GTPL 4X6AL 2R92L 4BBRL 3S16L 4BY7L 5C44L 4A93L 4Y7NL 3S17L 4A3EL 2WB1P 2JA6L 3S2HL 3GTML 2NVYL 4BBSL 4A3IL 1SFOL 5M5YL 4QIWP 5C3EL 3HOZL 1TWGL 2JA8L 1Y1VL 3PO3L 1TWFL 2PMZP 2Y0SP 3FKIL 5C4JL 5M3FL 3GTQL 4A3BL 5M5WL 4C2M1 4A3GL 3CQZL 3HOVL 4A3KL 4A3FL 3H3VM 1I50L 2NVXL 3S1RL 2E2HL 4A3CL 3PO2L 3HOWL 3M3YL 4A3DL 3GTLL 2WAQP 3RZDL 3GTGL 5IYBL 2E2IL 5C4XL 1Y1WL 1I6HL 2NVTL 3HOUL 3I4ML 3HKZP 3S15L 4BXXL 3GTOL 4C3JL 2NVQL 2JA5L 2VUML 1TWCL 2R93L 4Y52L 4C3IL 4A3JL 4AYBP 3GTJL
chains in the Genus database with same CATH superfamily
2JI3A 5FJ8L 2E2JL 2V3BB 3KYYA 2K2DA 3A44A 2JI1A 5IP9L 1IW7D 3JR7A 2YU9L 3RZTA 1CAAA 2J9UB 4JAGA 5MF6A 3HOYL 2LCQA 5M5XL 3RZOL 1YUZA 2KKDA 3WWLA 1R9TL 3B0AB 2ZIXA 5MFPA 4LHNA 5GADc 2R92L 3MQKB 4BBRL 4A93L 3S17L 4AHZA 2WB1P 1Z92B 1PZXA 5IY0A 3GTML 2NVYL 4AHYA 4U671 1VZIA 2A69D 3KYUA 4QIWP 2PPTA 2JI2A 3PL5A 1Y1VL 2Z3RB 5C4JL 2PVEA 3KYVA 5M5WL 8RXNA 1YV1A 3HOVL 3FDJA 1NNQA 1I50L 3S1RL 1NXEA 2CR8A 2E2HL 4AR6A 3PKJA 2XJRA 3PO2L 2H12A 2WAQP 3B08B 4B8CD 1I6HL 2NVTL 4ME3A 2CKAA 3HKZP 4BXXL 1B13A 3S15L 4C3JL 2GMGA 1S30A 1PFVA 1FHHA 2RFKB 3GTJL 1RYQA 1R0HA 5IYDL 4YWMA 2MS3A 1R0FA 3S2DL 5JVH1 4A3LL 2QL0A 4BY1L 4A3ML 1DX8A 2M6OA 3LPEB 4UY81 4V196 4POGA 1TWAL 1SMMA 5IYCL 2XJSA 3I4NL 3MSUA 4XXBB 1BQ8A 4BY7L 5C44L 3LWPB 4A3EL 2JA6L 2Z3QB 2ERJA 1PFYA 4ZN3B 3J7Y1 4A3IL 4TVMA 5C3EL 1R0GA 1ZRPA 5DM61 1TWFL 3FKIL 5M3FL 4A3BL 1IU5A 4A3GL 2L0ZA 4A3KL 3RYGA 1R0JA 2BE5D 4A3FL 1VZGA 2NVXL 1DVBA 2HVYC 4AHXA 3M3YL 3GTLL 3GTGL 5IYBL 4WFN1 1T9QA 4JAFA 4AR4A 1RWDA 3HOUL 2NVQL 2M6PA 4Y52L 2ERSA 1F4LA 1I3QL 1RDVA 1TWHL 3H97A 1QCVA 1PFUA 3KYWA 5FLML 5GAEc 2APOB 2XJVA 1BE7A 4AR3A 4C3HL 3M4OL 1YK5A 2B5ID 1FHMA 5AI3A 2XJPA 3GTKL 2M4YA 3PIP1 4ZN1B 1H7VA 4GS7D 7RXNA 3S14L 3SS2A 3H9BA 1BQ9A 3LWQB 2R7ZL 1SMUA 5M3ML 3PZAA 5K2ME 3GTPL 1LKMA 4X6AL 2PSMC 4G6BA 3S16L 3VPBE 1ODHA 3ZG6A 4BBSL 1SFOL 3HOZL 3LNLA 2XJTA 2V0FA 4XGHA 5MGNA 1VCXA 3RZ6A 1RB9A 2XJQA 4C2M1 3QVDA 2V0EA 6RXNA 3P8BA 5RXNA 3J7Z1 3QQCE 4JAEA 2AYJA 2A6ED 3H99A 3H3VM 4AR5A 2DSXA 1NXGA 1LKPA 2A6HD 4TPUA 1QYBA 3HOWL 2O5JD 1IROA 4A3DL 1RYTA 1OWBA 3RZDL 1S2ZA 1T9PA 5GAHc 2E2IL 5C4XL 2PYAA 1Y1WL 3KYXA 5GAGc 1E8JA 5EINC 3I4ML 3HJWB 3GTOL 3K35A 2JA5L 1YUXA 1T9OA 1TWCL 2R93L 3HJYB 4A3JL 1QQTA 4AI1A 1B2OA 2CKCA 1WJVA 5EIOC 3S1ML 1VZHA 1R0IA 1B2JA 3S1QL 1OWCA 2B63L 3PWFA 4AI2A 2JA7L 2M4VA 1IU6A 3PKIA 2EY4E 3S1NL 1K83L 1PFWA 3LWOB 3LWVB 4YWLA 3PIO1 2C6AA 3K7AL 5MLC3 2RDVA 3MPSA 5IP7L 3H0GL 1WCML 3HOXL 4Y7NL 3H9CA 5AN9H 1S24A 2AQCA 3S2HL 1SMWA 1YK4A 5M5YL 1P7PA 2VL6A 1TWGL 2JA8L 1RDGA 3PO3L 4RXNA 1IRNA 2PMZP 2Y0SP 4JADA 3GTQL 3WWNB 1LKOA 4K9FA 4LHLA 5DM71 3CQZL 1BFYA 3NFPI 3LWRB 2XJUA 1LTLA 1JYBA 5MFZA 1B71A 1C09A 4A3CL 4POFA 2AUSB 3HAXC 4AHWA 4AI3A 2PVXA 3P2AA 5AI2A 2HR5A 5JVG1 4AI0A 1BRFA 2NYDA 4E6YA 5H1Sc 2A68D 2C6BA 3IU3I 2VUML 4C3IL 2KN9A 4AYBP 1CADA
chains in the Genus database with same CATH topology
1I3QL 1TWHL 5FJ8L 3S1ML 2E2JL 5FLML 5IYDL 3S1QL 2B63L 4C3HL 2JA7L 3M4OL 3S2DL 5IP9L 4A3LL 3GTKL 4BY1L 3S1NL 4A3ML 2YU9L 1K83L 3HOYL 5M5XL 3S14L 3RZOL 3K7AL 1TWAL 5IYCL 1R9TL 3I4NL 2R7ZL 5IP7L 3H0GL 5M3ML 1WCML 3HOXL 3GTPL 4X6AL 2R92L 4BBRL 3S16L 4BY7L 5C44L 4A93L 4Y7NL 3S17L 4A3EL 2WB1P 2JA6L 3S2HL 3GTML 2NVYL 4BBSL 4A3IL 1SFOL 5M5YL 4QIWP 5C3EL 3HOZL 1TWGL 2JA8L 1Y1VL 3PO3L 1TWFL 2PMZP 2Y0SP 3FKIL 5C4JL 5M3FL 3GTQL 4A3BL 5M5WL 4C2M1 4A3GL 3CQZL 3HOVL 4A3KL 4A3FL 3H3VM 1I50L 2NVXL 3S1RL 2E2HL 4A3CL 3PO2L 3HOWL 3M3YL 4A3DL 3GTLL 2WAQP 3RZDL 3GTGL 5IYBL 2E2IL 5C4XL 1Y1WL 1I6HL 2NVTL 3HOUL 3I4ML 3HKZP 3S15L 4BXXL 3GTOL 4C3JL 2NVQL 2JA5L 2VUML 1TWCL 2R93L 4Y52L 4C3IL 4A3JL 4AYBP 3GTJL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I3Q L;  1TWH L;  5FJ8 L;  3S1M L;  2E2J L;  5FLM L;  5IYD L;  3S1Q L;  2B63 L;  4C3H L;  2JA7 L;  3M4O L;  3S2D L;  5IP9 L;  4A3L L;  3GTK L;  4BY1 L;  3S1N L;  4A3M L;  2YU9 L;  1K83 L;  3HOY L;  5M5X L;  3S14 L;  3RZO L;  3K7A L;  1TWA L;  5IYC L;  1R9T L;  3I4N L;  2R7Z L;  5IP7 L;  3H0G L;  5M3M L;  1WCM L;  3HOX L;  3GTP L;  4X6A L;  2R92 L;  4BBR L;  3S16 L;  4BY7 L;  5C44 L;  4A93 L;  4Y7N L;  3S17 L;  4A3E L;  2WB1 P;  2JA6 L;  3S2H L;  3GTM L;  2NVY L;  4BBS L;  4A3I L;  1SFO L;  5M5Y L;  4QIW P;  5C3E L;  3HOZ L;  1TWG L;  2JA8 L;  1Y1V L;  3PO3 L;  1TWF L;  2PMZ P;  2Y0S P;  3FKI L;  5C4J L;  5M3F L;  3GTQ L;  4A3B L;  5M5W L;  4C2M 1;  4A3G L;  3CQZ L;  3HOV L;  4A3K L;  4A3F L;  3H3V M;  1I50 L;  2NVX L;  3S1R L;  2E2H L;  4A3C L;  3PO2 L;  3HOW L;  3M3Y L;  4A3D L;  3GTL L;  2WAQ P;  3RZD L;  3GTG L;  5IYB L;  2E2I L;  5C4X L;  1Y1W L;  1I6H L;  2NVT L;  3HOU L;  3I4M L;  3HKZ P;  3S15 L;  4BXX L;  3GTO L;  4C3J L;  2NVQ L;  2JA5 L;  2VUM L;  1TWC L;  2R93 L;  4Y52 L;  4C3I L;  4A3J L;  4AYB P;  3GTJ L; 
#chains in the Genus database with same CATH topology
 2JI3 A;  5FJ8 L;  2E2J L;  2V3B B;  3KYY A;  2K2D A;  3A44 A;  2JI1 A;  5IP9 L;  1IW7 D;  3JR7 A;  2YU9 L;  3RZT A;  1CAA A;  2J9U B;  4JAG A;  5MF6 A;  3HOY L;  2LCQ A;  5M5X L;  3RZO L;  1YUZ A;  2KKD A;  3WWL A;  1R9T L;  3B0A B;  2ZIX A;  5MFP A;  4LHN A;  5GAD c;  2R92 L;  3MQK B;  4BBR L;  4A93 L;  3S17 L;  4AHZ A;  2WB1 P;  1Z92 B;  1PZX A;  5IY0 A;  3GTM L;  2NVY L;  4AHY A;  4U67 1;  1VZI A;  2A69 D;  3KYU A;  4QIW P;  2PPT A;  2JI2 A;  3PL5 A;  1Y1V L;  2Z3R B;  5C4J L;  2PVE A;  3KYV A;  5M5W L;  8RXN A;  1YV1 A;  3HOV L;  3FDJ A;  1NNQ A;  1I50 L;  3S1R L;  1NXE A;  2CR8 A;  2E2H L;  4AR6 A;  3PKJ A;  2XJR A;  3PO2 L;  2H12 A;  2WAQ P;  3B08 B;  4B8C D;  1I6H L;  2NVT L;  4ME3 A;  2CKA A;  3HKZ P;  4BXX L;  1B13 A;  3S15 L;  4C3J L;  2GMG A;  1S30 A;  1PFV A;  1FHH A;  2RFK B;  3GTJ L;  1RYQ A;  1R0H A;  5IYD L;  4YWM A;  2MS3 A;  1R0F A;  3S2D L;  5JVH 1;  4A3L L;  2QL0 A;  4BY1 L;  4A3M L;  1DX8 A;  2M6O A;  3LPE B;  4UY8 1;  4V19 6;  4POG A;  1TWA L;  1SMM A;  5IYC L;  2XJS A;  3I4N L;  3MSU A;  4XXB B;  1BQ8 A;  4BY7 L;  5C44 L;  3LWP B;  4A3E L;  2JA6 L;  2Z3Q B;  2ERJ A;  1PFY A;  4ZN3 B;  3J7Y 1;  4A3I L;  4TVM A;  5C3E L;  1R0G A;  1ZRP A;  5DM6 1;  1TWF L;  3FKI L;  5M3F L;  4A3B L;  1IU5 A;  4A3G L;  2L0Z A;  4A3K L;  3RYG A;  1R0J A;  2BE5 D;  4A3F L;  1VZG A;  2NVX L;  1DVB A;  2HVY C;  4AHX A;  3M3Y L;  3GTL L;  3GTG L;  5IYB L;  4WFN 1;  1T9Q A;  4JAF A;  4AR4 A;  1RWD A;  3HOU L;  2NVQ L;  2M6P A;  4Y52 L;  2ERS A;  1F4L A;  1I3Q L;  1RDV A;  1TWH L;  3H97 A;  1QCV A;  1PFU A;  3KYW A;  5FLM L;  5GAE c;  2APO B;  2XJV A;  1BE7 A;  4AR3 A;  4C3H L;  3M4O L;  1YK5 A;  2B5I D;  1FHM A;  5AI3 A;  2XJP A;  3GTK L;  2M4Y A;  3PIP 1;  4ZN1 B;  1H7V A;  4GS7 D;  7RXN A;  3S14 L;  3SS2 A;  3H9B A;  1BQ9 A;  3LWQ B;  2R7Z L;  1SMU A;  5M3M L;  3PZA A;  5K2M E;  3GTP L;  1LKM A;  4X6A L;  2PSM C;  4G6B A;  3S16 L;  3VPB E;  1ODH A;  3ZG6 A;  4BBS L;  1SFO L;  3HOZ L;  3LNL A;  2XJT A;  2V0F A;  4XGH A;  5MGN A;  1VCX A;  3RZ6 A;  1RB9 A;  2XJQ A;  4C2M 1;  3QVD A;  2V0E A;  6RXN A;  3P8B A;  5RXN A;  3J7Z 1;  3QQC E;  4JAE A;  2AYJ A;  2A6E D;  3H99 A;  3H3V M;  4AR5 A;  2DSX A;  1NXG A;  1LKP A;  2A6H D;  4TPU A;  1QYB A;  3HOW L;  2O5J D;  1IRO A;  4A3D L;  1RYT A;  1OWB A;  3RZD L;  1S2Z A;  1T9P A;  5GAH c;  2E2I L;  5C4X L;  2PYA A;  1Y1W L;  3KYX A;  5GAG c;  1E8J A;  5EIN C;  3I4M L;  3HJW B;  3GTO L;  3K35 A;  2JA5 L;  1YUX A;  1T9O A;  1TWC L;  2R93 L;  3HJY B;  4A3J L;  1QQT A;  4AI1 A;  1B2O A;  2CKC A;  1WJV A;  5EIO C;  3S1M L;  1VZH A;  1R0I A;  1B2J A;  3S1Q L;  1OWC A;  2B63 L;  3PWF A;  4AI2 A;  2JA7 L;  2M4V A;  1IU6 A;  3PKI A;  2EY4 E;  3S1N L;  1K83 L;  1PFW A;  3LWO B;  3LWV B;  4YWL A;  3PIO 1;  2C6A A;  3K7A L;  5MLC 3;  2RDV A;  3MPS A;  5IP7 L;  3H0G L;  1WCM L;  3HOX L;  4Y7N L;  3H9C A;  5AN9 H;  1S24 A;  2AQC A;  3S2H L;  1SMW A;  1YK4 A;  5M5Y L;  1P7P A;  2VL6 A;  1TWG L;  2JA8 L;  1RDG A;  3PO3 L;  4RXN A;  1IRN A;  2PMZ P;  2Y0S P;  4JAD A;  3GTQ L;  3WWN B;  1LKO A;  4K9F A;  4LHL A;  5DM7 1;  3CQZ L;  1BFY A;  3NFP I;  3LWR B;  2XJU A;  1LTL A;  1JYB A;  5MFZ A;  1B71 A;  1C09 A;  4A3C L;  4POF A;  2AUS B;  3HAX C;  4AHW A;  4AI3 A;  2PVX A;  3P2A A;  5AI2 A;  2HR5 A;  5JVG 1;  4AI0 A;  1BRF A;  2NYD A;  4E6Y A;  5H1S c;  2A68 D;  2C6B A;  3IU3 I;  2VUM L;  4C3I L;  2KN9 A;  4AYB P;  1CAD A; 
#chains in the Genus database with same CATH homology
 1I3Q L;  1TWH L;  5FJ8 L;  3S1M L;  2E2J L;  5FLM L;  5IYD L;  3S1Q L;  2B63 L;  4C3H L;  2JA7 L;  3M4O L;  3S2D L;  5IP9 L;  4A3L L;  3GTK L;  4BY1 L;  3S1N L;  4A3M L;  2YU9 L;  1K83 L;  3HOY L;  5M5X L;  3S14 L;  3RZO L;  3K7A L;  1TWA L;  5IYC L;  1R9T L;  3I4N L;  2R7Z L;  5IP7 L;  3H0G L;  5M3M L;  1WCM L;  3HOX L;  3GTP L;  4X6A L;  2R92 L;  4BBR L;  3S16 L;  4BY7 L;  5C44 L;  4A93 L;  4Y7N L;  3S17 L;  4A3E L;  2WB1 P;  2JA6 L;  3S2H L;  3GTM L;  2NVY L;  4BBS L;  4A3I L;  1SFO L;  5M5Y L;  4QIW P;  5C3E L;  3HOZ L;  1TWG L;  2JA8 L;  1Y1V L;  3PO3 L;  1TWF L;  2PMZ P;  2Y0S P;  3FKI L;  5C4J L;  5M3F L;  3GTQ L;  4A3B L;  5M5W L;  4C2M 1;  4A3G L;  3CQZ L;  3HOV L;  4A3K L;  4A3F L;  3H3V M;  1I50 L;  2NVX L;  3S1R L;  2E2H L;  4A3C L;  3PO2 L;  3HOW L;  3M3Y L;  4A3D L;  3GTL L;  2WAQ P;  3RZD L;  3GTG L;  5IYB L;  2E2I L;  5C4X L;  1Y1W L;  1I6H L;  2NVT L;  3HOU L;  3I4M L;  3HKZ P;  3S15 L;  4BXX L;  3GTO L;  4C3J L;  2NVQ L;  2JA5 L;  2VUM L;  1TWC L;  2R93 L;  4Y52 L;  4C3I L;  4A3J L;  4AYB P;  3GTJ L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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