1I50L

Rna polymerase ii crystal form ii at 2.8 a resolution
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2001-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 1i50L00
2YU9L 5C4XL 5IYDL 1Y1WL 3GTLL 4A3KL 3H0GL 4A3JL 4A3CL 3CQZL 5M5WL 3HOZL 3HOWL 5C44L 5C3EL 5IYBL 5M3FL 2Y0SP 2WB1P 3PO3L 1R9TL 1SFOL 3S2DL 5C4JL 3S1QL 2JA7L 3K7AL 5M5YL 3GTKL 3GTPL 1K83L 1TWGL 2NVYL 4A3ML 4Y7NL 3GTML 3HKZP 3S1ML 1I6HL 4BXXL 1TWCL 2WAQP 3HOXL 3S17L 2NVXL 4X6AL 2R93L 2PMZP 4C3HL 3HOUL 3HOVL 3GTJL 5M3ML 4BBRL 2B63L 3PO2L 4A3LL 3S1RL 3S14L 3I4ML 4AYBP 5FJ8L 5FLML 3RZOL 4A3DL 3RZDL 2NVQL 5IYCL 4A3BL 4A3EL 1Y1VL 2E2IL 4BBSL 4A3GL 5IP7L 4BY7L 1I3QL 3FKIL 4QIWP 4C2M1 2R7ZL 4Y52L 3S16L 3S2HL 3S15L 4A3FL 3GTQL 3H3VM 1TWFL 1WCML 2E2JL 3GTGL 3S1NL 2NVTL 5M5XL 3M4OL 4A93L 2R92L 1TWHL 3I4NL 4BY1L 2JA5L 2VUML 1TWAL 4A3IL 4C3IL 5IP9L 3M3YL 4C3JL 2JA6L 2E2HL 3GTOL 2JA8L 3HOYL 1I50L
chains in the Genus database with same CATH superfamily
3RZ6A 2YU9L 1LKOA 1OWBA 1FHHA 5DM61 3HJYB 1B2JA 2VL6A 2KKDA 2M6OA 2Y0SP 3K35A 5GADc 3MSUA 3PO3L 4LHNA 1CAAA 2ERJA 5M5YL 1LKPA 1ZRPA 1K83L 5GAEc 3HKZP 3S1ML 1I6HL 3H99A 1YV1A 3H9CA 3QVDA 2NVXL 4C3HL 2BE5D 3HOUL 2A68D 1E8JA 2A6ED 4A3LL 3S1RL 1BRFA 3I4ML 2ZIXA 3P2AA 5FJ8L 3RZOL 4A3BL 4YWMA 2RFKB 1Y1VL 1IU5A 3LNLA 4YWLA 3KYXA 5IP7L 2R7ZL 4Y52L 1LTLA 4AHZA 3RYGA 1C09A 5AN9H 3GTQL 2DSXA 4AR5A 1S24A 1TWFL 3RZTA 5MLC3 3MPSA 1TWHL 3I4NL 4G6BA 2M4VA 1NXEA 2AQCA 1FHMA 5IY0A 2V0EA 4AI1A 2XJPA 2L0ZA 3ZG6A 1NNQA 2M6PA 1VZHA 2PSMC 3SS2A 2PYAA 1JYBA 1PFVA 3H0GL 1F4LA 5M5WL 4AHWA 1YK4A 1QCVA 2PVXA 2V0FA 3MQKB 2XJSA 1R9TL 2RDVA 3PWFA 4JADA 2KN9A 3K7AL 1DVBA 3B0AB 3GTPL 1SMUA 2XJRA 1PFYA 4Y7NL 5GAHc 4E6YA 1YUZA 1TWCL 3HOXL 1SMWA 3LWVB 2PMZP 2A6HD 1PFUA 3PO2L 4AR6A 2XJVA 5FLML 3JR7A 3RZDL 2HVYC 2JI1A 3PZAA 2Z3RB 4BY7L 3LWQB 4C2M1 3S16L 2GMGA 5JVG1 5EINC 1SMMA 1BQ8A 1B71A 2MS3A 2E2JL 3GTGL 1T9OA 5M5XL 3M4OL 5JVH1 4A93L 1B13A 1Z92B 2XJTA 1TWAL 1IROA 5K2ME 4GS7D 4UY81 2CKCA 1YUXA 4K9FA 4TVMA 2JA8L 1QQTA 3WWNB 1ODHA 4TPUA 5IYDL 4V196 2APOB 3KYUA 4ZN3B 3GTLL 1QYBA 2NYDA 4A3CL 2AYJA 3CQZL 3HOZL 1RB9A 1OWCA 1WJVA 5M3FL 1IW7D 2JI2A 2JI3A 2WB1P 2EY4E 4POFA 1RDVA 4JAFA 3S2DL 3HAXC 5C4JL 1R0GA 3S1QL 2XJUA 3H9BA 3GTKL 1RDGA 2PVEA 2Z3QB 1VZGA 2NVYL 1P7PA 3J7Y1 5GAGc 1BQ9A 2ERSA 4BXXL 2LCQA 2WAQP 2C6AA 1CADA 3PKIA 2XJQA 3PKJA 3A44A 4RXNA 2R93L 3WWLA 2H12A 3GTJL 1T9QA 5M3ML 2QL0A 4LHLA 5H1Sc 4ME3A 3IU3I 5RXNA 1RYQA 2PPTA 2V3BB 4A3EL 8RXNA 5AI2A 2C6BA 2E2IL 4BBSL 4A3GL 1R0JA 2J9UB 3B08B 3QQCE 2B5ID 3NFPI 3S15L 3P8BA 5DM71 2HR5A 3LWRB 4XXBB 1RYTA 1RWDA 3LWOB 3LWPB 3S1NL 3FDJA 1R0IA 4POGA 2R92L 7RXNA 4BY1L 5MFPA 2JA5L 5AI3A 4A3IL 3KYVA 4C3IL 3M3YL 4AI3A 4C3JL 4ZN1B 2E2HL 1BE7A 4AHXA 3GTOL 4B8CD 3HOYL 1VCXA 1I50L 5C4XL 3J7Z1 1Y1WL 3PIO1 4A3KL 4AR4A 4A3JL 1PFWA 4AI0A 1T9PA 3HOWL 5C44L 2AUSB 5C3EL 4JAGA 5IYBL 4AI2A 5MF6A 3H97A 1SFOL 1S30A 4U671 1IU6A 2JA7L 1S2ZA 3HJWB 1TWGL 4A3ML 3GTML 2A69D 3KYYA 1R0HA 4WFN1 3S17L 4X6AL 3HOVL 5MFZA 4BBRL 5MGNA 2B63L 3S14L 4AYBP 3KYWA 1VZIA 1H7VA 1R0FA 4A3DL 3PIP1 2NVQL 5IYCL 1BFYA 1PZXA 1LKMA 4JAEA 2CKAA 6RXNA 3LPEB 1I3QL 1B2OA 3FKIL 4QIWP 2O5JD 1YK5A 3S2HL 4A3FL 2K2DA 3H3VM 1WCML 2NVTL 2CR8A 3PL5A 1IRNA 4AHYA 1DX8A 2VUML 1NXGA 5IP9L 4AR3A 2JA6L 3VPBE 5EIOC 4XGHA 2M4YA
chains in the Genus database with same CATH topology
2YU9L 5C4XL 5IYDL 1Y1WL 3GTLL 4A3KL 3H0GL 4A3JL 4A3CL 3CQZL 5M5WL 3HOZL 3HOWL 5C44L 5C3EL 5IYBL 5M3FL 2Y0SP 2WB1P 3PO3L 1R9TL 1SFOL 3S2DL 5C4JL 3S1QL 2JA7L 3K7AL 5M5YL 3GTKL 3GTPL 1K83L 1TWGL 2NVYL 4A3ML 4Y7NL 3GTML 3HKZP 3S1ML 1I6HL 4BXXL 1TWCL 2WAQP 3HOXL 3S17L 2NVXL 4X6AL 2R93L 2PMZP 4C3HL 3HOUL 3HOVL 3GTJL 5M3ML 4BBRL 2B63L 3PO2L 4A3LL 3S1RL 3S14L 3I4ML 4AYBP 5FJ8L 5FLML 3RZOL 4A3DL 3RZDL 2NVQL 5IYCL 4A3BL 4A3EL 1Y1VL 2E2IL 4BBSL 4A3GL 5IP7L 4BY7L 1I3QL 3FKIL 4QIWP 4C2M1 2R7ZL 4Y52L 3S16L 3S2HL 3S15L 4A3FL 3GTQL 3H3VM 1TWFL 1WCML 2E2JL 3GTGL 3S1NL 2NVTL 5M5XL 3M4OL 4A93L 2R92L 1TWHL 3I4NL 4BY1L 2JA5L 2VUML 1TWAL 4A3IL 4C3IL 5IP9L 3M3YL 4C3JL 2JA6L 2E2HL 3GTOL 2JA8L 3HOYL 1I50L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YU9 L;  5C4X L;  5IYD L;  1Y1W L;  3GTL L;  4A3K L;  3H0G L;  4A3J L;  4A3C L;  3CQZ L;  5M5W L;  3HOZ L;  3HOW L;  5C44 L;  5C3E L;  5IYB L;  5M3F L;  2Y0S P;  2WB1 P;  3PO3 L;  1R9T L;  1SFO L;  3S2D L;  5C4J L;  3S1Q L;  2JA7 L;  3K7A L;  5M5Y L;  3GTK L;  3GTP L;  1K83 L;  1TWG L;  2NVY L;  4A3M L;  4Y7N L;  3GTM L;  3HKZ P;  3S1M L;  1I6H L;  4BXX L;  1TWC L;  2WAQ P;  3HOX L;  3S17 L;  2NVX L;  4X6A L;  2R93 L;  2PMZ P;  4C3H L;  3HOU L;  3HOV L;  3GTJ L;  5M3M L;  4BBR L;  2B63 L;  3PO2 L;  4A3L L;  3S1R L;  3S14 L;  3I4M L;  4AYB P;  5FJ8 L;  5FLM L;  3RZO L;  4A3D L;  3RZD L;  2NVQ L;  5IYC L;  4A3B L;  4A3E L;  1Y1V L;  2E2I L;  4BBS L;  4A3G L;  5IP7 L;  4BY7 L;  1I3Q L;  3FKI L;  4QIW P;  4C2M 1;  2R7Z L;  4Y52 L;  3S16 L;  3S2H L;  3S15 L;  4A3F L;  3GTQ L;  3H3V M;  1TWF L;  1WCM L;  2E2J L;  3GTG L;  3S1N L;  2NVT L;  5M5X L;  3M4O L;  4A93 L;  2R92 L;  1TWH L;  3I4N L;  4BY1 L;  2JA5 L;  2VUM L;  1TWA L;  4A3I L;  4C3I L;  5IP9 L;  3M3Y L;  4C3J L;  2JA6 L;  2E2H L;  3GTO L;  2JA8 L;  3HOY L;  1I50 L; 
#chains in the Genus database with same CATH topology
 3RZ6 A;  2YU9 L;  1LKO A;  1OWB A;  1FHH A;  5DM6 1;  3HJY B;  1B2J A;  2VL6 A;  2KKD A;  2M6O A;  2Y0S P;  3K35 A;  5GAD c;  3MSU A;  3PO3 L;  4LHN A;  1CAA A;  2ERJ A;  5M5Y L;  1LKP A;  1ZRP A;  1K83 L;  5GAE c;  3HKZ P;  3S1M L;  1I6H L;  3H99 A;  1YV1 A;  3H9C A;  3QVD A;  2NVX L;  4C3H L;  2BE5 D;  3HOU L;  2A68 D;  1E8J A;  2A6E D;  4A3L L;  3S1R L;  1BRF A;  3I4M L;  2ZIX A;  3P2A A;  5FJ8 L;  3RZO L;  4A3B L;  4YWM A;  2RFK B;  1Y1V L;  1IU5 A;  3LNL A;  4YWL A;  3KYX A;  5IP7 L;  2R7Z L;  4Y52 L;  1LTL A;  4AHZ A;  3RYG A;  1C09 A;  5AN9 H;  3GTQ L;  2DSX A;  4AR5 A;  1S24 A;  1TWF L;  3RZT A;  5MLC 3;  3MPS A;  1TWH L;  3I4N L;  4G6B A;  2M4V A;  1NXE A;  2AQC A;  1FHM A;  5IY0 A;  2V0E A;  4AI1 A;  2XJP A;  2L0Z A;  3ZG6 A;  1NNQ A;  2M6P A;  1VZH A;  2PSM C;  3SS2 A;  2PYA A;  1JYB A;  1PFV A;  3H0G L;  1F4L A;  5M5W L;  4AHW A;  1YK4 A;  1QCV A;  2PVX A;  2V0F A;  3MQK B;  2XJS A;  1R9T L;  2RDV A;  3PWF A;  4JAD A;  2KN9 A;  3K7A L;  1DVB A;  3B0A B;  3GTP L;  1SMU A;  2XJR A;  1PFY A;  4Y7N L;  5GAH c;  4E6Y A;  1YUZ A;  1TWC L;  3HOX L;  1SMW A;  3LWV B;  2PMZ P;  2A6H D;  1PFU A;  3PO2 L;  4AR6 A;  2XJV A;  5FLM L;  3JR7 A;  3RZD L;  2HVY C;  2JI1 A;  3PZA A;  2Z3R B;  4BY7 L;  3LWQ B;  4C2M 1;  3S16 L;  2GMG A;  5JVG 1;  5EIN C;  1SMM A;  1BQ8 A;  1B71 A;  2MS3 A;  2E2J L;  3GTG L;  1T9O A;  5M5X L;  3M4O L;  5JVH 1;  4A93 L;  1B13 A;  1Z92 B;  2XJT A;  1TWA L;  1IRO A;  5K2M E;  4GS7 D;  4UY8 1;  2CKC A;  1YUX A;  4K9F A;  4TVM A;  2JA8 L;  1QQT A;  3WWN B;  1ODH A;  4TPU A;  5IYD L;  4V19 6;  2APO B;  3KYU A;  4ZN3 B;  3GTL L;  1QYB A;  2NYD A;  4A3C L;  2AYJ A;  3CQZ L;  3HOZ L;  1RB9 A;  1OWC A;  1WJV A;  5M3F L;  1IW7 D;  2JI2 A;  2JI3 A;  2WB1 P;  2EY4 E;  4POF A;  1RDV A;  4JAF A;  3S2D L;  3HAX C;  5C4J L;  1R0G A;  3S1Q L;  2XJU A;  3H9B A;  3GTK L;  1RDG A;  2PVE A;  2Z3Q B;  1VZG A;  2NVY L;  1P7P A;  3J7Y 1;  5GAG c;  1BQ9 A;  2ERS A;  4BXX L;  2LCQ A;  2WAQ P;  2C6A A;  1CAD A;  3PKI A;  2XJQ A;  3PKJ A;  3A44 A;  4RXN A;  2R93 L;  3WWL A;  2H12 A;  3GTJ L;  1T9Q A;  5M3M L;  2QL0 A;  4LHL A;  5H1S c;  4ME3 A;  3IU3 I;  5RXN A;  1RYQ A;  2PPT A;  2V3B B;  4A3E L;  8RXN A;  5AI2 A;  2C6B A;  2E2I L;  4BBS L;  4A3G L;  1R0J A;  2J9U B;  3B08 B;  3QQC E;  2B5I D;  3NFP I;  3S15 L;  3P8B A;  5DM7 1;  2HR5 A;  3LWR B;  4XXB B;  1RYT A;  1RWD A;  3LWO B;  3LWP B;  3S1N L;  3FDJ A;  1R0I A;  4POG A;  2R92 L;  7RXN A;  4BY1 L;  5MFP A;  2JA5 L;  5AI3 A;  4A3I L;  3KYV A;  4C3I L;  3M3Y L;  4AI3 A;  4C3J L;  4ZN1 B;  2E2H L;  1BE7 A;  4AHX A;  3GTO L;  4B8C D;  3HOY L;  1VCX A;  1I50 L;  5C4X L;  3J7Z 1;  1Y1W L;  3PIO 1;  4A3K L;  4AR4 A;  4A3J L;  1PFW A;  4AI0 A;  1T9P A;  3HOW L;  5C44 L;  2AUS B;  5C3E L;  4JAG A;  5IYB L;  4AI2 A;  5MF6 A;  3H97 A;  1SFO L;  1S30 A;  4U67 1;  1IU6 A;  2JA7 L;  1S2Z A;  3HJW B;  1TWG L;  4A3M L;  3GTM L;  2A69 D;  3KYY A;  1R0H A;  4WFN 1;  3S17 L;  4X6A L;  3HOV L;  5MFZ A;  4BBR L;  5MGN A;  2B63 L;  3S14 L;  4AYB P;  3KYW A;  1VZI A;  1H7V A;  1R0F A;  4A3D L;  3PIP 1;  2NVQ L;  5IYC L;  1BFY A;  1PZX A;  1LKM A;  4JAE A;  2CKA A;  6RXN A;  3LPE B;  1I3Q L;  1B2O A;  3FKI L;  4QIW P;  2O5J D;  1YK5 A;  3S2H L;  4A3F L;  2K2D A;  3H3V M;  1WCM L;  2NVT L;  2CR8 A;  3PL5 A;  1IRN A;  4AHY A;  1DX8 A;  2VUM L;  1NXG A;  5IP9 L;  4AR3 A;  2JA6 L;  3VPB E;  5EIO C;  4XGH A;  2M4Y A; 
#chains in the Genus database with same CATH homology
 2YU9 L;  5C4X L;  5IYD L;  1Y1W L;  3GTL L;  4A3K L;  3H0G L;  4A3J L;  4A3C L;  3CQZ L;  5M5W L;  3HOZ L;  3HOW L;  5C44 L;  5C3E L;  5IYB L;  5M3F L;  2Y0S P;  2WB1 P;  3PO3 L;  1R9T L;  1SFO L;  3S2D L;  5C4J L;  3S1Q L;  2JA7 L;  3K7A L;  5M5Y L;  3GTK L;  3GTP L;  1K83 L;  1TWG L;  2NVY L;  4A3M L;  4Y7N L;  3GTM L;  3HKZ P;  3S1M L;  1I6H L;  4BXX L;  1TWC L;  2WAQ P;  3HOX L;  3S17 L;  2NVX L;  4X6A L;  2R93 L;  2PMZ P;  4C3H L;  3HOU L;  3HOV L;  3GTJ L;  5M3M L;  4BBR L;  2B63 L;  3PO2 L;  4A3L L;  3S1R L;  3S14 L;  3I4M L;  4AYB P;  5FJ8 L;  5FLM L;  3RZO L;  4A3D L;  3RZD L;  2NVQ L;  5IYC L;  4A3B L;  4A3E L;  1Y1V L;  2E2I L;  4BBS L;  4A3G L;  5IP7 L;  4BY7 L;  1I3Q L;  3FKI L;  4QIW P;  4C2M 1;  2R7Z L;  4Y52 L;  3S16 L;  3S2H L;  3S15 L;  4A3F L;  3GTQ L;  3H3V M;  1TWF L;  1WCM L;  2E2J L;  3GTG L;  3S1N L;  2NVT L;  5M5X L;  3M4O L;  4A93 L;  2R92 L;  1TWH L;  3I4N L;  4BY1 L;  2JA5 L;  2VUM L;  1TWA L;  4A3I L;  4C3I L;  5IP9 L;  3M3Y L;  4C3J L;  2JA6 L;  2E2H L;  3GTO L;  2JA8 L;  3HOY L;  1I50 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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