1K83L

Crystal structure of yeast rna polymerase ii complexed with the inhibitor alpha amanitin
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
45
structure length
45
Chain Sequence
TLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Transcription: Alpha-Amanitin-RNA Polymerase II Cocrystal at 2.8 A Resolution.
pubmed doi rcsb
molecule tags Transcription/toxin
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 1
structure length 45
sequence length 45
ec nomenclature
pdb deposition date 2001-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 1k83L00
4A3BL 1I3QL 2E2JL 2E2IL 2JA6L 2JA8L 3GTJL 3S17L 3H0GL 4QIWP 4A3JL 4A3EL 2NVTL 3GTML 4A3DL 4C2M1 3S15L 2YU9L 1TWCL 2WAQP 2Y0SP 4A3FL 1TWAL 3RZOL 4C3JL 2NVXL 5C3EL 2NVQL 3H3VM 3M3YL 3HOWL 3S1NL 3GTPL 4Y52L 2B63L 1TWGL 2R7ZL 3S14L 2NVYL 2VUML 5FJ8L 5IP9L 1TWFL 4BY1L 2E2HL 4AYBP 1I6HL 1Y1VL 4A3ML 5FLML 5M5YL 1R9TL 4BBSL 3CQZL 1Y1WL 3PO3L 4Y7NL 5M3FL 3HOUL 2R92L 3GTLL 5C4XL 4BY7L 4A3IL 5M5XL 3HOZL 1WCML 3GTGL 3I4ML 3I4NL 5IYCL 3S1QL 3HOVL 2R93L 4X6AL 1K83L 3M4OL 3FKIL 5C44L 4A3KL 4A3CL 4C3IL 2JA5L 3S1RL 4A3GL 2PMZP 3HOYL 5M5WL 4BXXL 3K7AL 5M3ML 3S1ML 1SFOL 3S2HL 1I50L 2WB1P 3GTKL 4C3HL 5IYBL 2JA7L 3GTQL 5IP7L 5IYDL 3S16L 1TWHL 3RZDL 3HOXL 4BBRL 5C4JL 3PO2L 3HKZP 4A93L 4A3LL 3S2DL 3GTOL
chains in the Genus database with same CATH superfamily
4POGA 1FHHA 2B5ID 5GAHc 4A3BL 2C6AA 1VZGA 2E2IL 2M4YA 1DX8A 2JA8L 1PFVA 1T9QA 4AI2A 2NVTL 2AQCA 3LWOB 3S15L 1CADA 1YV1A 1TWAL 4AHWA 5MFZA 4Y52L 1IW7D 1RDGA 2ERSA 1B13A 5IY0A 4JADA 2VUML 2DSXA 1CAAA 1LTLA 2A68D 3PKIA 5FLML 1R9TL 5GADc 4AHZA 1WJVA 3WWNB 3HOUL 2R92L 3KYVA 4K9FA 3GTLL 3H9BA 4A3IL 5M5XL 3SS2A 2GMGA 2EY4E 2HVYC 1IRNA 3RZ6A 3HOVL 1K83L 3VPBE 1PFYA 3FKIL 3LWVB 3S1RL 3FDJA 2PMZP 2APOB 1DVBA 4BXXL 5M3ML 3QQCE 1VZIA 1QCVA 1I50L 2WB1P 2AUSB 4C3HL 1B2OA 3PIP1 3P2AA 1YK5A 3PO2L 3HKZP 2CR8A 3GTOL 3HJYB 1I3QL 5MFPA 2PPTA 1OWBA 1T9PA 3A44A 2HR5A 3PWFA 3H0GL 5K2ME 4A3JL 1QYBA 1BFYA 2YU9L 1TWCL 2XJVA 5JVG1 2WAQP 2Y0SP 5AN9H 5MF6A 2NVXL 3P8BA 5C3EL 2NVQL 3HOWL 3S1NL 2JI1A 3LWRB 2M6OA 2JI2A 2L0ZA 2NVYL 2PSMC 1TWFL 4AI1A 1I6HL 3RYGA 1B2JA 4A3ML 4GS7D 2M6PA 4BBSL 5GAEc 3KYXA 1PZXA 4XXBB 4Y7NL 2LCQA 2XJSA 3PKJA 4JAEA 3KYYA 2JI3A 3HOZL 1SMUA 4AHYA 3S1QL 1FHMA 1T9OA 4TVMA 3M4OL 1E8JA 3MPSA 2A6HD 1YUXA 5MGNA 3H99A 1R0IA 4JAGA 1SFOL 3S1ML 3H97A 1IROA 3MQKB 3KYUA 5IYBL 2Z3QB 1BQ9A 5AI3A 5IYDL 1LKMA 1TWHL 3RZDL 1B71A 1Z92B 2M4VA 1R0JA 4BBRL 4A3LL 2CKCA 3IU3I 2JA6L 1LKOA 2XJTA 1YUZA 2RDVA 3GTJL 4AI3A 4A3DL 1OWCA 4E6YA 2QL0A 1RYQA 2XJRA 4POFA 1BQ8A 5DM61 1PFUA 4C3JL 1S30A 1P7PA 5DM71 3RZTA 4XGHA 1H7VA 3M3YL 2XJUA 2V0EA 2B63L 1YK4A 2R7ZL 3S14L 2RFKB 7RXNA 4YWLA 5IP9L 5JVH1 2XJPA 4BY1L 1RYTA 1SMMA 3H9CA 5RXNA 1Y1VL 1VCXA 1NNQA 3CQZL 4AHXA 1R0FA 1ODHA 1PFWA 5M3FL 5C4XL 4BY7L 3I4ML 3J7Y1 3I4NL 2KKDA 3HJWB 5IYCL 2R93L 3LPEB 2CKAA 5C44L 4A3CL 4V196 3PIO1 2JA5L 3LWQB 2Z3RB 3HOYL 3K7AL 2K2DA 3HAXC 4RXNA 3J7Z1 1S24A 3GTQL 2PYAA 5AI2A 4ZN3B 1NXEA 1QQTA 4A93L 1IU6A 3S2DL 2E2JL 3PL5A 4UY81 1VZHA 4U671 4ME3A 3JR7A 3S17L 4QIWP 5GAGc 4A3EL 1RWDA 4WFN1 3GTML 2PVXA 3QVDA 4C2M1 4A3FL 5EIOC 3KYWA 3RZOL 1BRFA 1C09A 3B0AB 2XJQA 1BE7A 1IU5A 3H3VM 3GTPL 2KN9A 1TWGL 8RXNA 5FJ8L 1RDVA 2A6ED 4G6BA 5H1Sc 2E2HL 2VL6A 4AYBP 2V0FA 1RB9A 4AR3A 4TPUA 1F4LA 5M5YL 3PZAA 1NXGA 1Y1WL 3PO3L 4B8CD 1R0HA 3NFPI 1R0GA 4AR4A 1S2ZA 3LWPB 2ZIXA 3MSUA 1WCML 3GTGL 1SMWA 4X6AL 2ERJA 4LHNA 2NYDA 4A3KL 4C3IL 3WWLA 2C6BA 4A3GL 3LNLA 2O5JD 5M5WL 4JAFA 3S2HL 4AI0A 2J9UB 1ZRPA 3ZG6A 3K35A 4ZN1B 3GTKL 2H12A 2MS3A 2JA7L 5IP7L 4YWMA 2AYJA 2PVEA 3S16L 3B08B 4LHLA 1JYBA 2BE5D 4AR5A 4AR6A 3HOXL 5C4JL 5MLC3 1LKPA 2V3BB 5EINC 6RXNA 2A69D
chains in the Genus database with same CATH topology
4A3BL 1I3QL 2E2JL 2E2IL 2JA6L 2JA8L 3GTJL 3S17L 3H0GL 4QIWP 4A3JL 4A3EL 2NVTL 3GTML 4A3DL 4C2M1 3S15L 2YU9L 1TWCL 2WAQP 2Y0SP 4A3FL 1TWAL 3RZOL 4C3JL 2NVXL 5C3EL 2NVQL 3H3VM 3M3YL 3HOWL 3S1NL 3GTPL 4Y52L 2B63L 1TWGL 2R7ZL 3S14L 2NVYL 2VUML 5FJ8L 5IP9L 1TWFL 4BY1L 2E2HL 4AYBP 1I6HL 1Y1VL 4A3ML 5FLML 5M5YL 1R9TL 4BBSL 3CQZL 1Y1WL 3PO3L 4Y7NL 5M3FL 3HOUL 2R92L 3GTLL 5C4XL 4BY7L 4A3IL 5M5XL 3HOZL 1WCML 3GTGL 3I4ML 3I4NL 5IYCL 3S1QL 3HOVL 2R93L 4X6AL 1K83L 3M4OL 3FKIL 5C44L 4A3KL 4A3CL 4C3IL 2JA5L 3S1RL 4A3GL 2PMZP 3HOYL 5M5WL 4BXXL 3K7AL 5M3ML 3S1ML 1SFOL 3S2HL 1I50L 2WB1P 3GTKL 4C3HL 5IYBL 2JA7L 3GTQL 5IP7L 5IYDL 3S16L 1TWHL 3RZDL 3HOXL 4BBRL 5C4JL 3PO2L 3HKZP 4A93L 4A3LL 3S2DL 3GTOL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3B L;  1I3Q L;  2E2J L;  2E2I L;  2JA6 L;  2JA8 L;  3GTJ L;  3S17 L;  3H0G L;  4QIW P;  4A3J L;  4A3E L;  2NVT L;  3GTM L;  4A3D L;  4C2M 1;  3S15 L;  2YU9 L;  1TWC L;  2WAQ P;  2Y0S P;  4A3F L;  1TWA L;  3RZO L;  4C3J L;  2NVX L;  5C3E L;  2NVQ L;  3H3V M;  3M3Y L;  3HOW L;  3S1N L;  3GTP L;  4Y52 L;  2B63 L;  1TWG L;  2R7Z L;  3S14 L;  2NVY L;  2VUM L;  5FJ8 L;  5IP9 L;  1TWF L;  4BY1 L;  2E2H L;  4AYB P;  1I6H L;  1Y1V L;  4A3M L;  5FLM L;  5M5Y L;  1R9T L;  4BBS L;  3CQZ L;  1Y1W L;  3PO3 L;  4Y7N L;  5M3F L;  3HOU L;  2R92 L;  3GTL L;  5C4X L;  4BY7 L;  4A3I L;  5M5X L;  3HOZ L;  1WCM L;  3GTG L;  3I4M L;  3I4N L;  5IYC L;  3S1Q L;  3HOV L;  2R93 L;  4X6A L;  1K83 L;  3M4O L;  3FKI L;  5C44 L;  4A3K L;  4A3C L;  4C3I L;  2JA5 L;  3S1R L;  4A3G L;  2PMZ P;  3HOY L;  5M5W L;  4BXX L;  3K7A L;  5M3M L;  3S1M L;  1SFO L;  3S2H L;  1I50 L;  2WB1 P;  3GTK L;  4C3H L;  5IYB L;  2JA7 L;  3GTQ L;  5IP7 L;  5IYD L;  3S16 L;  1TWH L;  3RZD L;  3HOX L;  4BBR L;  5C4J L;  3PO2 L;  3HKZ P;  4A93 L;  4A3L L;  3S2D L;  3GTO L; 
#chains in the Genus database with same CATH topology
 4POG A;  1FHH A;  2B5I D;  5GAH c;  4A3B L;  2C6A A;  1VZG A;  2E2I L;  2M4Y A;  1DX8 A;  2JA8 L;  1PFV A;  1T9Q A;  4AI2 A;  2NVT L;  2AQC A;  3LWO B;  3S15 L;  1CAD A;  1YV1 A;  1TWA L;  4AHW A;  5MFZ A;  4Y52 L;  1IW7 D;  1RDG A;  2ERS A;  1B13 A;  5IY0 A;  4JAD A;  2VUM L;  2DSX A;  1CAA A;  1LTL A;  2A68 D;  3PKI A;  5FLM L;  1R9T L;  5GAD c;  4AHZ A;  1WJV A;  3WWN B;  3HOU L;  2R92 L;  3KYV A;  4K9F A;  3GTL L;  3H9B A;  4A3I L;  5M5X L;  3SS2 A;  2GMG A;  2EY4 E;  2HVY C;  1IRN A;  3RZ6 A;  3HOV L;  1K83 L;  3VPB E;  1PFY A;  3FKI L;  3LWV B;  3S1R L;  3FDJ A;  2PMZ P;  2APO B;  1DVB A;  4BXX L;  5M3M L;  3QQC E;  1VZI A;  1QCV A;  1I50 L;  2WB1 P;  2AUS B;  4C3H L;  1B2O A;  3PIP 1;  3P2A A;  1YK5 A;  3PO2 L;  3HKZ P;  2CR8 A;  3GTO L;  3HJY B;  1I3Q L;  5MFP A;  2PPT A;  1OWB A;  1T9P A;  3A44 A;  2HR5 A;  3PWF A;  3H0G L;  5K2M E;  4A3J L;  1QYB A;  1BFY A;  2YU9 L;  1TWC L;  2XJV A;  5JVG 1;  2WAQ P;  2Y0S P;  5AN9 H;  5MF6 A;  2NVX L;  3P8B A;  5C3E L;  2NVQ L;  3HOW L;  3S1N L;  2JI1 A;  3LWR B;  2M6O A;  2JI2 A;  2L0Z A;  2NVY L;  2PSM C;  1TWF L;  4AI1 A;  1I6H L;  3RYG A;  1B2J A;  4A3M L;  4GS7 D;  2M6P A;  4BBS L;  5GAE c;  3KYX A;  1PZX A;  4XXB B;  4Y7N L;  2LCQ A;  2XJS A;  3PKJ A;  4JAE A;  3KYY A;  2JI3 A;  3HOZ L;  1SMU A;  4AHY A;  3S1Q L;  1FHM A;  1T9O A;  4TVM A;  3M4O L;  1E8J A;  3MPS A;  2A6H D;  1YUX A;  5MGN A;  3H99 A;  1R0I A;  4JAG A;  1SFO L;  3S1M L;  3H97 A;  1IRO A;  3MQK B;  3KYU A;  5IYB L;  2Z3Q B;  1BQ9 A;  5AI3 A;  5IYD L;  1LKM A;  1TWH L;  3RZD L;  1B71 A;  1Z92 B;  2M4V A;  1R0J A;  4BBR L;  4A3L L;  2CKC A;  3IU3 I;  2JA6 L;  1LKO A;  2XJT A;  1YUZ A;  2RDV A;  3GTJ L;  4AI3 A;  4A3D L;  1OWC A;  4E6Y A;  2QL0 A;  1RYQ A;  2XJR A;  4POF A;  1BQ8 A;  5DM6 1;  1PFU A;  4C3J L;  1S30 A;  1P7P A;  5DM7 1;  3RZT A;  4XGH A;  1H7V A;  3M3Y L;  2XJU A;  2V0E A;  2B63 L;  1YK4 A;  2R7Z L;  3S14 L;  2RFK B;  7RXN A;  4YWL A;  5IP9 L;  5JVH 1;  2XJP A;  4BY1 L;  1RYT A;  1SMM A;  3H9C A;  5RXN A;  1Y1V L;  1VCX A;  1NNQ A;  3CQZ L;  4AHX A;  1R0F A;  1ODH A;  1PFW A;  5M3F L;  5C4X L;  4BY7 L;  3I4M L;  3J7Y 1;  3I4N L;  2KKD A;  3HJW B;  5IYC L;  2R93 L;  3LPE B;  2CKA A;  5C44 L;  4A3C L;  4V19 6;  3PIO 1;  2JA5 L;  3LWQ B;  2Z3R B;  3HOY L;  3K7A L;  2K2D A;  3HAX C;  4RXN A;  3J7Z 1;  1S24 A;  3GTQ L;  2PYA A;  5AI2 A;  4ZN3 B;  1NXE A;  1QQT A;  4A93 L;  1IU6 A;  3S2D L;  2E2J L;  3PL5 A;  4UY8 1;  1VZH A;  4U67 1;  4ME3 A;  3JR7 A;  3S17 L;  4QIW P;  5GAG c;  4A3E L;  1RWD A;  4WFN 1;  3GTM L;  2PVX A;  3QVD A;  4C2M 1;  4A3F L;  5EIO C;  3KYW A;  3RZO L;  1BRF A;  1C09 A;  3B0A B;  2XJQ A;  1BE7 A;  1IU5 A;  3H3V M;  3GTP L;  2KN9 A;  1TWG L;  8RXN A;  5FJ8 L;  1RDV A;  2A6E D;  4G6B A;  5H1S c;  2E2H L;  2VL6 A;  4AYB P;  2V0F A;  1RB9 A;  4AR3 A;  4TPU A;  1F4L A;  5M5Y L;  3PZA A;  1NXG A;  1Y1W L;  3PO3 L;  4B8C D;  1R0H A;  3NFP I;  1R0G A;  4AR4 A;  1S2Z A;  3LWP B;  2ZIX A;  3MSU A;  1WCM L;  3GTG L;  1SMW A;  4X6A L;  2ERJ A;  4LHN A;  2NYD A;  4A3K L;  4C3I L;  3WWL A;  2C6B A;  4A3G L;  3LNL A;  2O5J D;  5M5W L;  4JAF A;  3S2H L;  4AI0 A;  2J9U B;  1ZRP A;  3ZG6 A;  3K35 A;  4ZN1 B;  3GTK L;  2H12 A;  2MS3 A;  2JA7 L;  5IP7 L;  4YWM A;  2AYJ A;  2PVE A;  3S16 L;  3B08 B;  4LHL A;  1JYB A;  2BE5 D;  4AR5 A;  4AR6 A;  3HOX L;  5C4J L;  5MLC 3;  1LKP A;  2V3B B;  5EIN C;  6RXN A;  2A69 D; 
#chains in the Genus database with same CATH homology
 4A3B L;  1I3Q L;  2E2J L;  2E2I L;  2JA6 L;  2JA8 L;  3GTJ L;  3S17 L;  3H0G L;  4QIW P;  4A3J L;  4A3E L;  2NVT L;  3GTM L;  4A3D L;  4C2M 1;  3S15 L;  2YU9 L;  1TWC L;  2WAQ P;  2Y0S P;  4A3F L;  1TWA L;  3RZO L;  4C3J L;  2NVX L;  5C3E L;  2NVQ L;  3H3V M;  3M3Y L;  3HOW L;  3S1N L;  3GTP L;  4Y52 L;  2B63 L;  1TWG L;  2R7Z L;  3S14 L;  2NVY L;  2VUM L;  5FJ8 L;  5IP9 L;  1TWF L;  4BY1 L;  2E2H L;  4AYB P;  1I6H L;  1Y1V L;  4A3M L;  5FLM L;  5M5Y L;  1R9T L;  4BBS L;  3CQZ L;  1Y1W L;  3PO3 L;  4Y7N L;  5M3F L;  3HOU L;  2R92 L;  3GTL L;  5C4X L;  4BY7 L;  4A3I L;  5M5X L;  3HOZ L;  1WCM L;  3GTG L;  3I4M L;  3I4N L;  5IYC L;  3S1Q L;  3HOV L;  2R93 L;  4X6A L;  1K83 L;  3M4O L;  3FKI L;  5C44 L;  4A3K L;  4A3C L;  4C3I L;  2JA5 L;  3S1R L;  4A3G L;  2PMZ P;  3HOY L;  5M5W L;  4BXX L;  3K7A L;  5M3M L;  3S1M L;  1SFO L;  3S2H L;  1I50 L;  2WB1 P;  3GTK L;  4C3H L;  5IYB L;  2JA7 L;  3GTQ L;  5IP7 L;  5IYD L;  3S16 L;  1TWH L;  3RZD L;  3HOX L;  4BBR L;  5C4J L;  3PO2 L;  3HKZ P;  4A93 L;  4A3L L;  3S2D L;  3GTO L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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