2NVYL

Rna polymerase ii form ii in 150 mm mn+2
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase II largest subunit
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2006-11-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2nvyL00
1TWHL 5IYBL 3GTGL 3HOYL 2Y0SP 1TWGL 5C4JL 3RZDL 1R9TL 5IP7L 3HOXL 3S17L 3PO3L 2E2IL 5IYDL 3HOZL 2E2HL 3H0GL 4Y7NL 1SFOL 4A3BL 4A3ML 4C3IL 4C2M1 4C3JL 4AYBP 4BY1L 3S2HL 3HOVL 2WAQP 3GTPL 2PMZP 2JA5L 5IYCL 4QIWP 2YU9L 3GTKL 4C3HL 2B63L 2R93L 3HOUL 4BY7L 3S1ML 3GTJL 5FJ8L 3FKIL 1K83L 1I50L 4A93L 4A3FL 1TWFL 5M3ML 2JA6L 2R7ZL 2NVQL 2E2JL 3M3YL 3GTOL 4A3KL 4A3EL 4A3JL 3S1RL 3S15L 4A3IL 5IP9L 5M5XL 3HKZP 2JA7L 5M3FL 2R92L 5C44L 3S1NL 1WCML 3PO2L 5M5WL 2JA8L 2NVXL 5M5YL 1TWCL 4BBRL 2VUML 4BXXL 2NVYL 3H3VM 3CQZL 3S14L 5C4XL 3I4ML 3S2DL 2NVTL 3GTML 3S16L 4A3DL 3M4OL 2WB1P 3GTLL 4A3CL 3GTQL 3K7AL 3RZOL 4Y52L 1Y1VL 1Y1WL 1TWAL 4A3LL 1I6HL 3HOWL 4X6AL 5FLML 5C3EL 1I3QL 4BBSL 3I4NL 4A3GL 3S1QL
chains in the Genus database with same CATH superfamily
2C6BA 3HOYL 1JYBA 3A44A 1NXGA 1CADA 5MF6A 1P7PA 1BQ9A 3LWRB 5GADc 2AYJA 5AN9H 2O5JD 1B71A 4BY1L 1YUZA 3S2HL 3HOVL 1OWBA 3GTPL 3LPEB 3NFPI 2CKAA 4YWMA 4AR5A 3P8BA 1QQTA 4QIWP 2KKDA 2RFKB 2B63L 2HR5A 2BE5D 3S1ML 2XJTA 3GTJL 5FJ8L 2PYAA 2VL6A 5EINC 4AR4A 5AI2A 2QL0A 4A3FL 1TWFL 5M3ML 3LWOB 1RDVA 3PIP1 3JR7A 4AI0A 1S24A 4A3EL 3PZAA 1QYBA 2XJQA 4A3IL 3H99A 5M3FL 2M4VA 5GAHc 2JI2A 5C44L 3S1NL 1ODHA 4AR6A 1PZXA 2NVXL 5M5YL 5H1Sc 1TWCL 2A69D 2V0EA 1H7VA 1YUXA 3CQZL 3S14L 3PIO1 5C4XL 4ZN3B 1SMUA 1NNQA 3KYWA 4A3DL 3M4OL 4LHLA 4A3CL 2A6ED 4JAFA 2J9UB 1Y1VL 3QVDA 3HOWL 3PL5A 1YK4A 2DSXA 2K2DA 5FLML 1B13A 2Z3QB 1I3QL 1BQ8A 5DM61 3LWPB 7RXNA 1R0GA 5IYBL 2Y0SP 4AHYA 4JAGA 5C4JL 3RZDL 3LWQB 3HOXL 5IYDL 3HOZL 2AQCA 3KYUA 2C6AA 1SFOL 1RYQA 6RXNA 1FHMA 4C3IL 1ZRPA 4AHWA 2WAQP 1PFUA 2PMZP 2JA5L 2R93L 2JI1A 3HOUL 1IROA 4BY7L 3MQKB 1K83L 1I50L 1BFYA 3P2AA 2M4YA 4JADA 1S30A 2L0ZA 1LTLA 3MSUA 4JAEA 1T9OA 1WJVA 5IP9L 5M5XL 2R92L 2PSMC 1PFWA 2CR8A 4YWLA 4UY81 2VUML 3H3VM 3KYYA 2B5ID 2NVTL 3GTML 3S16L 1T9QA 1S2ZA 3ZG6A 4K9FA 4Y52L 3J7Z1 5DM71 2JI3A 1PFVA 2GMGA 2M6OA 1DX8A 4ZN1B 5C3EL 3I4NL 3B08B 5EIOC 3HAXC 2XJVA 1TWHL 3GTGL 4AR3A 1TWGL 3B0AB 3WWLA 8RXNA 1DVBA 3PO3L 3S17L 3H0GL 4A3ML 1LKOA 4C3JL 3WWNB 3H9BA 2XJRA 2ERSA 5JVG1 4POGA 2ERJA 4V196 2YU9L 1R0IA 2PVXA 3GTKL 4C3HL 1BRFA 3MPSA 2MS3A 1VZGA 3QQCE 1E8JA 2A6HD 3KYVA 3RZ6A 2ZIXA 3PWFA 5MFZA 1IU5A 4A93L 3VPBE 2XJPA 1Z92B 2NVQL 1VCXA 4TVMA 2APOB 3GTOL 4GS7D 4A3KL 3SS2A 2A68D 4AHZA 4A3JL 3S15L 5AI3A 2RDVA 1SMMA 2JA8L 3HJYB 1R0HA 1VZIA 1QCVA 1FHHA 3KYXA 4TPUA 5RXNA 4BXXL 2NVYL 1T9PA 3H97A 1BE7A 4AI2A 2LCQA 4U671 3GTQL 1Y1WL 1B2JA 1TWAL 4A3LL 1IRNA 1R0JA 2KN9A 2NYDA 2AUSB 3FDJA 2Z3RB 4B8CD 4XGHA 1R9TL 1LKPA 4AI3A 5IP7L 1RWDA 3PKIA 2E2IL 4Y7NL 2E2HL 4A3BL 4ME3A 4C2M1 4AYBP 1RYTA 5IYCL 1B2OA 5JVH1 4AI1A 2XJSA 2XJUA 3LNLA 3PKJA 1C09A 3FKIL 4WFN1 5IY0A 1PFYA 2M6PA 2JA6L 5GAEc 2R7ZL 2E2JL 3M3YL 4RXNA 2HVYC 4POFA 1SMWA 4AHXA 1RDGA 4G6BA 1R0FA 1IU6A 1LKMA 3S1RL 1NXEA 1YK5A 2PPTA 5K2ME 3HKZP 2JA7L 2V0FA 4XXBB 4E6YA 3J7Y1 3HJWB 3IU3I 3H9CA 1WCML 3PO2L 5M5WL 3K35A 1CAAA 2PVEA 1YV1A 4BBRL 2EY4E 1OWCA 5MGNA 5MFPA 3I4ML 3S2DL 1IW7D 2WB1P 3GTLL 5MLC3 5GAGc 3K7AL 3RZOL 1I6HL 4X6AL 4LHNA 1RB9A 3LWVB 2CKCA 1VZHA 3RYGA 1F4LA 2V3BB 4BBSL 3RZTA 2H12A 4A3GL 3S1QL
chains in the Genus database with same CATH topology
1TWHL 5IYBL 3GTGL 3HOYL 2Y0SP 1TWGL 5C4JL 3RZDL 1R9TL 5IP7L 3HOXL 3S17L 3PO3L 2E2IL 5IYDL 3HOZL 2E2HL 3H0GL 4Y7NL 1SFOL 4A3BL 4A3ML 4C3IL 4C2M1 4C3JL 4AYBP 4BY1L 3S2HL 3HOVL 2WAQP 3GTPL 2PMZP 2JA5L 5IYCL 4QIWP 2YU9L 3GTKL 4C3HL 2B63L 2R93L 3HOUL 4BY7L 3S1ML 3GTJL 5FJ8L 3FKIL 1K83L 1I50L 4A93L 4A3FL 1TWFL 5M3ML 2JA6L 2R7ZL 2NVQL 2E2JL 3M3YL 3GTOL 4A3KL 4A3EL 4A3JL 3S1RL 3S15L 4A3IL 5IP9L 5M5XL 3HKZP 2JA7L 5M3FL 2R92L 5C44L 3S1NL 1WCML 3PO2L 5M5WL 2JA8L 2NVXL 5M5YL 1TWCL 4BBRL 2VUML 4BXXL 2NVYL 3H3VM 3CQZL 3S14L 5C4XL 3I4ML 3S2DL 2NVTL 3GTML 3S16L 4A3DL 3M4OL 2WB1P 3GTLL 4A3CL 3GTQL 3K7AL 3RZOL 4Y52L 1Y1VL 1Y1WL 1TWAL 4A3LL 1I6HL 3HOWL 4X6AL 5FLML 5C3EL 1I3QL 4BBSL 3I4NL 4A3GL 3S1QL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TWH L;  5IYB L;  3GTG L;  3HOY L;  2Y0S P;  1TWG L;  5C4J L;  3RZD L;  1R9T L;  5IP7 L;  3HOX L;  3S17 L;  3PO3 L;  2E2I L;  5IYD L;  3HOZ L;  2E2H L;  3H0G L;  4Y7N L;  1SFO L;  4A3B L;  4A3M L;  4C3I L;  4C2M 1;  4C3J L;  4AYB P;  4BY1 L;  3S2H L;  3HOV L;  2WAQ P;  3GTP L;  2PMZ P;  2JA5 L;  5IYC L;  4QIW P;  2YU9 L;  3GTK L;  4C3H L;  2B63 L;  2R93 L;  3HOU L;  4BY7 L;  3S1M L;  3GTJ L;  5FJ8 L;  3FKI L;  1K83 L;  1I50 L;  4A93 L;  4A3F L;  1TWF L;  5M3M L;  2JA6 L;  2R7Z L;  2NVQ L;  2E2J L;  3M3Y L;  3GTO L;  4A3K L;  4A3E L;  4A3J L;  3S1R L;  3S15 L;  4A3I L;  5IP9 L;  5M5X L;  3HKZ P;  2JA7 L;  5M3F L;  2R92 L;  5C44 L;  3S1N L;  1WCM L;  3PO2 L;  5M5W L;  2JA8 L;  2NVX L;  5M5Y L;  1TWC L;  4BBR L;  2VUM L;  4BXX L;  2NVY L;  3H3V M;  3CQZ L;  3S14 L;  5C4X L;  3I4M L;  3S2D L;  2NVT L;  3GTM L;  3S16 L;  4A3D L;  3M4O L;  2WB1 P;  3GTL L;  4A3C L;  3GTQ L;  3K7A L;  3RZO L;  4Y52 L;  1Y1V L;  1Y1W L;  1TWA L;  4A3L L;  1I6H L;  3HOW L;  4X6A L;  5FLM L;  5C3E L;  1I3Q L;  4BBS L;  3I4N L;  4A3G L;  3S1Q L; 
#chains in the Genus database with same CATH topology
 2C6B A;  3HOY L;  1JYB A;  3A44 A;  1NXG A;  1CAD A;  5MF6 A;  1P7P A;  1BQ9 A;  3LWR B;  5GAD c;  2AYJ A;  5AN9 H;  2O5J D;  1B71 A;  4BY1 L;  1YUZ A;  3S2H L;  3HOV L;  1OWB A;  3GTP L;  3LPE B;  3NFP I;  2CKA A;  4YWM A;  4AR5 A;  3P8B A;  1QQT A;  4QIW P;  2KKD A;  2RFK B;  2B63 L;  2HR5 A;  2BE5 D;  3S1M L;  2XJT A;  3GTJ L;  5FJ8 L;  2PYA A;  2VL6 A;  5EIN C;  4AR4 A;  5AI2 A;  2QL0 A;  4A3F L;  1TWF L;  5M3M L;  3LWO B;  1RDV A;  3PIP 1;  3JR7 A;  4AI0 A;  1S24 A;  4A3E L;  3PZA A;  1QYB A;  2XJQ A;  4A3I L;  3H99 A;  5M3F L;  2M4V A;  5GAH c;  2JI2 A;  5C44 L;  3S1N L;  1ODH A;  4AR6 A;  1PZX A;  2NVX L;  5M5Y L;  5H1S c;  1TWC L;  2A69 D;  2V0E A;  1H7V A;  1YUX A;  3CQZ L;  3S14 L;  3PIO 1;  5C4X L;  4ZN3 B;  1SMU A;  1NNQ A;  3KYW A;  4A3D L;  3M4O L;  4LHL A;  4A3C L;  2A6E D;  4JAF A;  2J9U B;  1Y1V L;  3QVD A;  3HOW L;  3PL5 A;  1YK4 A;  2DSX A;  2K2D A;  5FLM L;  1B13 A;  2Z3Q B;  1I3Q L;  1BQ8 A;  5DM6 1;  3LWP B;  7RXN A;  1R0G A;  5IYB L;  2Y0S P;  4AHY A;  4JAG A;  5C4J L;  3RZD L;  3LWQ B;  3HOX L;  5IYD L;  3HOZ L;  2AQC A;  3KYU A;  2C6A A;  1SFO L;  1RYQ A;  6RXN A;  1FHM A;  4C3I L;  1ZRP A;  4AHW A;  2WAQ P;  1PFU A;  2PMZ P;  2JA5 L;  2R93 L;  2JI1 A;  3HOU L;  1IRO A;  4BY7 L;  3MQK B;  1K83 L;  1I50 L;  1BFY A;  3P2A A;  2M4Y A;  4JAD A;  1S30 A;  2L0Z A;  1LTL A;  3MSU A;  4JAE A;  1T9O A;  1WJV A;  5IP9 L;  5M5X L;  2R92 L;  2PSM C;  1PFW A;  2CR8 A;  4YWL A;  4UY8 1;  2VUM L;  3H3V M;  3KYY A;  2B5I D;  2NVT L;  3GTM L;  3S16 L;  1T9Q A;  1S2Z A;  3ZG6 A;  4K9F A;  4Y52 L;  3J7Z 1;  5DM7 1;  2JI3 A;  1PFV A;  2GMG A;  2M6O A;  1DX8 A;  4ZN1 B;  5C3E L;  3I4N L;  3B08 B;  5EIO C;  3HAX C;  2XJV A;  1TWH L;  3GTG L;  4AR3 A;  1TWG L;  3B0A B;  3WWL A;  8RXN A;  1DVB A;  3PO3 L;  3S17 L;  3H0G L;  4A3M L;  1LKO A;  4C3J L;  3WWN B;  3H9B A;  2XJR A;  2ERS A;  5JVG 1;  4POG A;  2ERJ A;  4V19 6;  2YU9 L;  1R0I A;  2PVX A;  3GTK L;  4C3H L;  1BRF A;  3MPS A;  2MS3 A;  1VZG A;  3QQC E;  1E8J A;  2A6H D;  3KYV A;  3RZ6 A;  2ZIX A;  3PWF A;  5MFZ A;  1IU5 A;  4A93 L;  3VPB E;  2XJP A;  1Z92 B;  2NVQ L;  1VCX A;  4TVM A;  2APO B;  3GTO L;  4GS7 D;  4A3K L;  3SS2 A;  2A68 D;  4AHZ A;  4A3J L;  3S15 L;  5AI3 A;  2RDV A;  1SMM A;  2JA8 L;  3HJY B;  1R0H A;  1VZI A;  1QCV A;  1FHH A;  3KYX A;  4TPU A;  5RXN A;  4BXX L;  2NVY L;  1T9P A;  3H97 A;  1BE7 A;  4AI2 A;  2LCQ A;  4U67 1;  3GTQ L;  1Y1W L;  1B2J A;  1TWA L;  4A3L L;  1IRN A;  1R0J A;  2KN9 A;  2NYD A;  2AUS B;  3FDJ A;  2Z3R B;  4B8C D;  4XGH A;  1R9T L;  1LKP A;  4AI3 A;  5IP7 L;  1RWD A;  3PKI A;  2E2I L;  4Y7N L;  2E2H L;  4A3B L;  4ME3 A;  4C2M 1;  4AYB P;  1RYT A;  5IYC L;  1B2O A;  5JVH 1;  4AI1 A;  2XJS A;  2XJU A;  3LNL A;  3PKJ A;  1C09 A;  3FKI L;  4WFN 1;  5IY0 A;  1PFY A;  2M6P A;  2JA6 L;  5GAE c;  2R7Z L;  2E2J L;  3M3Y L;  4RXN A;  2HVY C;  4POF A;  1SMW A;  4AHX A;  1RDG A;  4G6B A;  1R0F A;  1IU6 A;  1LKM A;  3S1R L;  1NXE A;  1YK5 A;  2PPT A;  5K2M E;  3HKZ P;  2JA7 L;  2V0F A;  4XXB B;  4E6Y A;  3J7Y 1;  3HJW B;  3IU3 I;  3H9C A;  1WCM L;  3PO2 L;  5M5W L;  3K35 A;  1CAA A;  2PVE A;  1YV1 A;  4BBR L;  2EY4 E;  1OWC A;  5MGN A;  5MFP A;  3I4M L;  3S2D L;  1IW7 D;  2WB1 P;  3GTL L;  5MLC 3;  5GAG c;  3K7A L;  3RZO L;  1I6H L;  4X6A L;  4LHN A;  1RB9 A;  3LWV B;  2CKC A;  1VZH A;  3RYG A;  1F4L A;  2V3B B;  4BBS L;  3RZT A;  2H12 A;  4A3G L;  3S1Q L; 
#chains in the Genus database with same CATH homology
 1TWH L;  5IYB L;  3GTG L;  3HOY L;  2Y0S P;  1TWG L;  5C4J L;  3RZD L;  1R9T L;  5IP7 L;  3HOX L;  3S17 L;  3PO3 L;  2E2I L;  5IYD L;  3HOZ L;  2E2H L;  3H0G L;  4Y7N L;  1SFO L;  4A3B L;  4A3M L;  4C3I L;  4C2M 1;  4C3J L;  4AYB P;  4BY1 L;  3S2H L;  3HOV L;  2WAQ P;  3GTP L;  2PMZ P;  2JA5 L;  5IYC L;  4QIW P;  2YU9 L;  3GTK L;  4C3H L;  2B63 L;  2R93 L;  3HOU L;  4BY7 L;  3S1M L;  3GTJ L;  5FJ8 L;  3FKI L;  1K83 L;  1I50 L;  4A93 L;  4A3F L;  1TWF L;  5M3M L;  2JA6 L;  2R7Z L;  2NVQ L;  2E2J L;  3M3Y L;  3GTO L;  4A3K L;  4A3E L;  4A3J L;  3S1R L;  3S15 L;  4A3I L;  5IP9 L;  5M5X L;  3HKZ P;  2JA7 L;  5M3F L;  2R92 L;  5C44 L;  3S1N L;  1WCM L;  3PO2 L;  5M5W L;  2JA8 L;  2NVX L;  5M5Y L;  1TWC L;  4BBR L;  2VUM L;  4BXX L;  2NVY L;  3H3V M;  3CQZ L;  3S14 L;  5C4X L;  3I4M L;  3S2D L;  2NVT L;  3GTM L;  3S16 L;  4A3D L;  3M4O L;  2WB1 P;  3GTL L;  4A3C L;  3GTQ L;  3K7A L;  3RZO L;  4Y52 L;  1Y1V L;  1Y1W L;  1TWA L;  4A3L L;  1I6H L;  3HOW L;  4X6A L;  5FLM L;  5C3E L;  1I3Q L;  4BBS L;  3I4N L;  4A3G L;  3S1Q L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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