2R7ZL

Cisplatin lesion containing rna polymerase ii elongation complex
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 5'-D(*TP*AP*CP*TP*TP*GUP*CP*CP*CP*TP*CP*CP*TP*CP*AP*T)-3'
publication title Mechanism of transcriptional stalling at cisplatin-damaged DNA.
pubmed doi rcsb
molecule tags Transcription/dna-rna hybrid
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2007-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2r7zL00
4C3JL 2JA6L 4BY7L 5C44L 2NVYL 4Y52L 2E2JL 2R7ZL 5M3ML 3S15L 4AYBP 5M3FL 5C3EL 3S14L 3S2HL 3GTML 2R93L 4QIWP 1TWGL 1I6HL 3GTLL 3I4NL 4A3GL 2Y0SP 4A3KL 1Y1VL 2WB1P 3GTKL 2NVXL 3M3YL 3HOZL 3GTQL 2NVTL 4A3LL 1I3QL 4BBSL 2R92L 5IP7L 1WCML 3GTOL 3S1ML 4A3EL 3S1NL 2PMZP 2E2HL 3RZOL 3S1RL 4A3ML 3HOYL 3GTJL 2VUML 1SFOL 3S17L 4A93L 2JA7L 3K7AL 3RZDL 3FKIL 4BBRL 3HOUL 4A3BL 3S2DL 4A3JL 4BY1L 3HKZP 4A3DL 3CQZL 5M5XL 3S16L 5FLML 5IYCL 3PO3L 4C3IL 2JA5L 1I50L 5M5WL 2WAQP 2JA8L 4A3FL 1K83L 3H0GL 2E2IL 4C2M1 2YU9L 3M4OL 1TWFL 5C4XL 1TWCL 5IYDL 3S1QL 5IP9L 1Y1WL 3HOVL 3I4ML 5M5YL 1TWAL 4C3HL 5FJ8L 1TWHL 1R9TL 3PO2L 4X6AL 5C4JL 3GTPL 3HOWL 4A3IL 3HOXL 2NVQL 4BXXL 4Y7NL 4A3CL 2B63L 3GTGL 5IYBL 3H3VM
chains in the Genus database with same CATH superfamily
4RXNA 3KYWA 1LTLA 2RDVA 4AHZA 3LPEB 1R0FA 1B71A 2APOB 2E2JL 4G6BA 1NXEA 1NNQA 3KYVA 2VL6A 4YWLA 1PFUA 3PIP1 5GAHc 1VZHA 1TWGL 1I6HL 3I4NL 1F4LA 4A3GL 2AYJA 2Y0SP 1BQ8A 4AI0A 3H97A 1T9OA 3LWOB 2PVXA 4BBSL 4AI3A 3S1ML 4ZN3B 2XJPA 1B2JA 4POGA 3KYYA 5DM71 5AI3A 4TVMA 4LHNA 1IU5A 4U671 1H7VA 2JA7L 4XXBB 7RXNA 3RZDL 4BBRL 3S2DL 3CQZL 1WJVA 2M6OA 4XGHA 5M5XL 1C09A 5JVG1 1VCXA 1IROA 2Z3RB 1BE7A 2M6PA 3H0GL 4C2M1 5MFPA 3M4OL 5C4XL 3WWLA 3S1QL 1PZXA 1RYTA 3WWNB 5GAEc 6RXNA 2A6HD 3LWVB 3PO2L 4X6AL 3P2AA 3HOWL 2C6AA 3A44A 2MS3A 5AN9H 4POFA 4Y7NL 2NYDA 3GTGL 5IYBL 4YWMA 2A6ED 2O5JD 4C3JL 2CKCA 2JA6L 5MF6A 1FHHA 2NVYL 3ZG6A 3MPSA 4AI2A 1S24A 3MSUA 3S15L 4AYBP 2XJTA 4LHLA 5C3EL 2ZIXA 3S2HL 2GMGA 1PFWA 3B08B 1T9PA 4AHWA 3H9BA 2XJUA 3SS2A 1RDGA 1S30A 2B5ID 5DM61 4GS7D 3KYUA 3GTKL 3M3YL 3LNLA 3GTQL 1RDVA 5MFZA 4A3LL 5AI2A 1NXGA 2R92L 3FDJA 1FHMA 5MLC3 1ODHA 3GTOL 2XJSA 2EY4E 3J7Z1 3PWFA 4A3ML 3RZ6A 3S1RL 1ZRPA 2VUML 3JR7A 3NFPI 1DVBA 3FKIL 4A3BL 3HKZP 3RZTA 2ERJA 2M4VA 2PVEA 2Z3QB 2HR5A 4ME3A 2CR8A 1I50L 2V3BB 4A3FL 1BQ9A 1TWFL 1TWCL 5IYDL 4ZN1B 3P8BA 3LWPB 3LWQB 5FJ8L 1DX8A 1LKPA 3GTPL 3HAXC 4A3IL 2NVQL 2HVYC 1VZIA 4BY7L 2K2DA 1LKOA 4Y52L 1QCVA 2PPTA 5H1Sc 3S14L 3HJWB 3GTML 2R93L 1R0IA 4QIWP 2XJVA 3GTLL 1B13A 5MGNA 3J7Y1 4AR6A 3IU3I 4A3KL 2PYAA 1Y1VL 4JAFA 2WB1P 1JYBA 5JVH1 1B2OA 4AR5A 2V0EA 3HOZL 2NVTL 1I3QL 2J9UB 3QVDA 2XJRA 4A3EL 3S1NL 4UY81 8RXNA 3RZOL 3HOYL 1E8JA 1CADA 4WFN1 4A93L 3PKIA 5IY0A 4JAGA 3HOUL 3KYXA 4A3DL 2ERSA 3S16L 5FLML 2RFKB 4TPUA 4K9FA 5IYCL 3PO3L 4C3IL 2JA5L 4B8CD 2C6BA 2V0FA 2BE5D 5M5WL 2WAQP 2JA8L 1SMWA 2KN9A 2YU9L 1R0GA 5K2ME 3QQCE 5IP9L 1Y1WL 1QQTA 1TWAL 3PL5A 3VPBE 1TWHL 2DSXA 1YK4A 3RYGA 3B0AB 3HOXL 3H99A 4AR3A 3H3VM 4JAEA 2AUSB 4AHXA 1SMMA 1YUZA 1RYQA 5C44L 1Z92B 2A69D 3K35A 5RXNA 2L0ZA 2R7ZL 5M3ML 5M3FL 2AQCA 3LWRB 3MQKB 2CKAA 1R0HA 2JI3A 4E6YA 2H12A 1RB9A 2PSMC 1R0JA 2NVXL 1PFVA 4AI1A 5GAGc 2LCQA 1S2ZA 1P7PA 3PIO1 1CAAA 2JI2A 5IP7L 1WCML 1PFYA 2JI1A 2PMZP 1VZGA 2E2HL 1T9QA 1YK5A 4JADA 1IW7D 2M4YA 1YV1A 3GTJL 3HJYB 1RWDA 5EINC 1OWCA 1SFOL 3S17L 1BFYA 1BRFA 3K7AL 4A3JL 4BY1L 2KKDA 2A68D 4AHYA 3H9CA 4V196 3PKJA 2XJQA 5EIOC 1YUXA 1SMUA 4AR4A 1K83L 1IRNA 2E2IL 1LKMA 3PZAA 1OWBA 1QYBA 3HOVL 3I4ML 5M5YL 4C3HL 1IU6A 1R9TL 5C4JL 2QL0A 4BXXL 4A3CL 2B63L 5GADc
chains in the Genus database with same CATH topology
4C3JL 2JA6L 4BY7L 5C44L 2NVYL 4Y52L 2E2JL 2R7ZL 5M3ML 3S15L 4AYBP 5M3FL 5C3EL 3S14L 3S2HL 3GTML 2R93L 4QIWP 1TWGL 1I6HL 3GTLL 3I4NL 4A3GL 2Y0SP 4A3KL 1Y1VL 2WB1P 3GTKL 2NVXL 3M3YL 3HOZL 3GTQL 2NVTL 4A3LL 1I3QL 4BBSL 2R92L 5IP7L 1WCML 3GTOL 3S1ML 4A3EL 3S1NL 2PMZP 2E2HL 3RZOL 3S1RL 4A3ML 3HOYL 3GTJL 2VUML 1SFOL 3S17L 4A93L 2JA7L 3K7AL 3RZDL 3FKIL 4BBRL 3HOUL 4A3BL 3S2DL 4A3JL 4BY1L 3HKZP 4A3DL 3CQZL 5M5XL 3S16L 5FLML 5IYCL 3PO3L 4C3IL 2JA5L 1I50L 5M5WL 2WAQP 2JA8L 4A3FL 1K83L 3H0GL 2E2IL 4C2M1 2YU9L 3M4OL 1TWFL 5C4XL 1TWCL 5IYDL 3S1QL 5IP9L 1Y1WL 3HOVL 3I4ML 5M5YL 1TWAL 4C3HL 5FJ8L 1TWHL 1R9TL 3PO2L 4X6AL 5C4JL 3GTPL 3HOWL 4A3IL 3HOXL 2NVQL 4BXXL 4Y7NL 4A3CL 2B63L 3GTGL 5IYBL 3H3VM
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C3J L;  2JA6 L;  4BY7 L;  5C44 L;  2NVY L;  4Y52 L;  2E2J L;  2R7Z L;  5M3M L;  3S15 L;  4AYB P;  5M3F L;  5C3E L;  3S14 L;  3S2H L;  3GTM L;  2R93 L;  4QIW P;  1TWG L;  1I6H L;  3GTL L;  3I4N L;  4A3G L;  2Y0S P;  4A3K L;  1Y1V L;  2WB1 P;  3GTK L;  2NVX L;  3M3Y L;  3HOZ L;  3GTQ L;  2NVT L;  4A3L L;  1I3Q L;  4BBS L;  2R92 L;  5IP7 L;  1WCM L;  3GTO L;  3S1M L;  4A3E L;  3S1N L;  2PMZ P;  2E2H L;  3RZO L;  3S1R L;  4A3M L;  3HOY L;  3GTJ L;  2VUM L;  1SFO L;  3S17 L;  4A93 L;  2JA7 L;  3K7A L;  3RZD L;  3FKI L;  4BBR L;  3HOU L;  4A3B L;  3S2D L;  4A3J L;  4BY1 L;  3HKZ P;  4A3D L;  3CQZ L;  5M5X L;  3S16 L;  5FLM L;  5IYC L;  3PO3 L;  4C3I L;  2JA5 L;  1I50 L;  5M5W L;  2WAQ P;  2JA8 L;  4A3F L;  1K83 L;  3H0G L;  2E2I L;  4C2M 1;  2YU9 L;  3M4O L;  1TWF L;  5C4X L;  1TWC L;  5IYD L;  3S1Q L;  5IP9 L;  1Y1W L;  3HOV L;  3I4M L;  5M5Y L;  1TWA L;  4C3H L;  5FJ8 L;  1TWH L;  1R9T L;  3PO2 L;  4X6A L;  5C4J L;  3GTP L;  3HOW L;  4A3I L;  3HOX L;  2NVQ L;  4BXX L;  4Y7N L;  4A3C L;  2B63 L;  3GTG L;  5IYB L;  3H3V M; 
#chains in the Genus database with same CATH topology
 4RXN A;  3KYW A;  1LTL A;  2RDV A;  4AHZ A;  3LPE B;  1R0F A;  1B71 A;  2APO B;  2E2J L;  4G6B A;  1NXE A;  1NNQ A;  3KYV A;  2VL6 A;  4YWL A;  1PFU A;  3PIP 1;  5GAH c;  1VZH A;  1TWG L;  1I6H L;  3I4N L;  1F4L A;  4A3G L;  2AYJ A;  2Y0S P;  1BQ8 A;  4AI0 A;  3H97 A;  1T9O A;  3LWO B;  2PVX A;  4BBS L;  4AI3 A;  3S1M L;  4ZN3 B;  2XJP A;  1B2J A;  4POG A;  3KYY A;  5DM7 1;  5AI3 A;  4TVM A;  4LHN A;  1IU5 A;  4U67 1;  1H7V A;  2JA7 L;  4XXB B;  7RXN A;  3RZD L;  4BBR L;  3S2D L;  3CQZ L;  1WJV A;  2M6O A;  4XGH A;  5M5X L;  1C09 A;  5JVG 1;  1VCX A;  1IRO A;  2Z3R B;  1BE7 A;  2M6P A;  3H0G L;  4C2M 1;  5MFP A;  3M4O L;  5C4X L;  3WWL A;  3S1Q L;  1PZX A;  1RYT A;  3WWN B;  5GAE c;  6RXN A;  2A6H D;  3LWV B;  3PO2 L;  4X6A L;  3P2A A;  3HOW L;  2C6A A;  3A44 A;  2MS3 A;  5AN9 H;  4POF A;  4Y7N L;  2NYD A;  3GTG L;  5IYB L;  4YWM A;  2A6E D;  2O5J D;  4C3J L;  2CKC A;  2JA6 L;  5MF6 A;  1FHH A;  2NVY L;  3ZG6 A;  3MPS A;  4AI2 A;  1S24 A;  3MSU A;  3S15 L;  4AYB P;  2XJT A;  4LHL A;  5C3E L;  2ZIX A;  3S2H L;  2GMG A;  1PFW A;  3B08 B;  1T9P A;  4AHW A;  3H9B A;  2XJU A;  3SS2 A;  1RDG A;  1S30 A;  2B5I D;  5DM6 1;  4GS7 D;  3KYU A;  3GTK L;  3M3Y L;  3LNL A;  3GTQ L;  1RDV A;  5MFZ A;  4A3L L;  5AI2 A;  1NXG A;  2R92 L;  3FDJ A;  1FHM A;  5MLC 3;  1ODH A;  3GTO L;  2XJS A;  2EY4 E;  3J7Z 1;  3PWF A;  4A3M L;  3RZ6 A;  3S1R L;  1ZRP A;  2VUM L;  3JR7 A;  3NFP I;  1DVB A;  3FKI L;  4A3B L;  3HKZ P;  3RZT A;  2ERJ A;  2M4V A;  2PVE A;  2Z3Q B;  2HR5 A;  4ME3 A;  2CR8 A;  1I50 L;  2V3B B;  4A3F L;  1BQ9 A;  1TWF L;  1TWC L;  5IYD L;  4ZN1 B;  3P8B A;  3LWP B;  3LWQ B;  5FJ8 L;  1DX8 A;  1LKP A;  3GTP L;  3HAX C;  4A3I L;  2NVQ L;  2HVY C;  1VZI A;  4BY7 L;  2K2D A;  1LKO A;  4Y52 L;  1QCV A;  2PPT A;  5H1S c;  3S14 L;  3HJW B;  3GTM L;  2R93 L;  1R0I A;  4QIW P;  2XJV A;  3GTL L;  1B13 A;  5MGN A;  3J7Y 1;  4AR6 A;  3IU3 I;  4A3K L;  2PYA A;  1Y1V L;  4JAF A;  2WB1 P;  1JYB A;  5JVH 1;  1B2O A;  4AR5 A;  2V0E A;  3HOZ L;  2NVT L;  1I3Q L;  2J9U B;  3QVD A;  2XJR A;  4A3E L;  3S1N L;  4UY8 1;  8RXN A;  3RZO L;  3HOY L;  1E8J A;  1CAD A;  4WFN 1;  4A93 L;  3PKI A;  5IY0 A;  4JAG A;  3HOU L;  3KYX A;  4A3D L;  2ERS A;  3S16 L;  5FLM L;  2RFK B;  4TPU A;  4K9F A;  5IYC L;  3PO3 L;  4C3I L;  2JA5 L;  4B8C D;  2C6B A;  2V0F A;  2BE5 D;  5M5W L;  2WAQ P;  2JA8 L;  1SMW A;  2KN9 A;  2YU9 L;  1R0G A;  5K2M E;  3QQC E;  5IP9 L;  1Y1W L;  1QQT A;  1TWA L;  3PL5 A;  3VPB E;  1TWH L;  2DSX A;  1YK4 A;  3RYG A;  3B0A B;  3HOX L;  3H99 A;  4AR3 A;  3H3V M;  4JAE A;  2AUS B;  4AHX A;  1SMM A;  1YUZ A;  1RYQ A;  5C44 L;  1Z92 B;  2A69 D;  3K35 A;  5RXN A;  2L0Z A;  2R7Z L;  5M3M L;  5M3F L;  2AQC A;  3LWR B;  3MQK B;  2CKA A;  1R0H A;  2JI3 A;  4E6Y A;  2H12 A;  1RB9 A;  2PSM C;  1R0J A;  2NVX L;  1PFV A;  4AI1 A;  5GAG c;  2LCQ A;  1S2Z A;  1P7P A;  3PIO 1;  1CAA A;  2JI2 A;  5IP7 L;  1WCM L;  1PFY A;  2JI1 A;  2PMZ P;  1VZG A;  2E2H L;  1T9Q A;  1YK5 A;  4JAD A;  1IW7 D;  2M4Y A;  1YV1 A;  3GTJ L;  3HJY B;  1RWD A;  5EIN C;  1OWC A;  1SFO L;  3S17 L;  1BFY A;  1BRF A;  3K7A L;  4A3J L;  4BY1 L;  2KKD A;  2A68 D;  4AHY A;  3H9C A;  4V19 6;  3PKJ A;  2XJQ A;  5EIO C;  1YUX A;  1SMU A;  4AR4 A;  1K83 L;  1IRN A;  2E2I L;  1LKM A;  3PZA A;  1OWB A;  1QYB A;  3HOV L;  3I4M L;  5M5Y L;  4C3H L;  1IU6 A;  1R9T L;  5C4J L;  2QL0 A;  4BXX L;  4A3C L;  2B63 L;  5GAD c; 
#chains in the Genus database with same CATH homology
 4C3J L;  2JA6 L;  4BY7 L;  5C44 L;  2NVY L;  4Y52 L;  2E2J L;  2R7Z L;  5M3M L;  3S15 L;  4AYB P;  5M3F L;  5C3E L;  3S14 L;  3S2H L;  3GTM L;  2R93 L;  4QIW P;  1TWG L;  1I6H L;  3GTL L;  3I4N L;  4A3G L;  2Y0S P;  4A3K L;  1Y1V L;  2WB1 P;  3GTK L;  2NVX L;  3M3Y L;  3HOZ L;  3GTQ L;  2NVT L;  4A3L L;  1I3Q L;  4BBS L;  2R92 L;  5IP7 L;  1WCM L;  3GTO L;  3S1M L;  4A3E L;  3S1N L;  2PMZ P;  2E2H L;  3RZO L;  3S1R L;  4A3M L;  3HOY L;  3GTJ L;  2VUM L;  1SFO L;  3S17 L;  4A93 L;  2JA7 L;  3K7A L;  3RZD L;  3FKI L;  4BBR L;  3HOU L;  4A3B L;  3S2D L;  4A3J L;  4BY1 L;  3HKZ P;  4A3D L;  3CQZ L;  5M5X L;  3S16 L;  5FLM L;  5IYC L;  3PO3 L;  4C3I L;  2JA5 L;  1I50 L;  5M5W L;  2WAQ P;  2JA8 L;  4A3F L;  1K83 L;  3H0G L;  2E2I L;  4C2M 1;  2YU9 L;  3M4O L;  1TWF L;  5C4X L;  1TWC L;  5IYD L;  3S1Q L;  5IP9 L;  1Y1W L;  3HOV L;  3I4M L;  5M5Y L;  1TWA L;  4C3H L;  5FJ8 L;  1TWH L;  1R9T L;  3PO2 L;  4X6A L;  5C4J L;  3GTP L;  3HOW L;  4A3I L;  3HOX L;  2NVQ L;  4BXX L;  4Y7N L;  4A3C L;  2B63 L;  3GTG L;  5IYB L;  3H3V M; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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