2R7ZL

Cisplatin lesion containing rna polymerase ii elongation complex
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
b'ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 5'-D(*TP*AP*CP*TP*TP*GUP*CP*CP*CP*TP*CP*CP*TP*CP*AP*T)-3'
publication title Mechanism of transcriptional stalling at cisplatin-damaged DNA.
pubmed doi rcsb
molecule tags Transcription/dna-rna hybrid
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2007-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2r7zL00
3GTOL 5IYCL 1TWCL 3I4NL 2E2HL 5C4XL 4X6AL 2R92L 2JA8L 3S16L 4C3JL 2NVQL 2R93L 1TWAL 2JA6L 1I3QL 4A3LL 4BBSL 5C4JL 5FLML 1I50L 3GTLL 3RZOL 3GTJL 2WB1P 4A3DL 4BY1L 4AYBP 3H3VM 2WAQP 4A3JL 2YU9L 1TWHL 2NVYL 2E2JL 1Y1VL 4A3BL 2NVXL 1SFOL 1TWGL 5IP7L 3HKZP 5M5XL 3PO2L 5IP9L 4Y7NL 4Y52L 1TWFL 4BY7L 5IYBL 5IYDL 3GTKL 2E2IL 2PMZP 3GTPL 4BXXL 4C2M1 3I4ML 3S14L 4A3ML 2R7ZL 2JA7L 3HOYL 1I6HL 3GTML 2Y0SP 4A3GL 1K83L 4A3EL 1R9TL 3HOUL 4A3FL 3S15L 3GTQL 3HOXL 5C44L 4A3KL 3HOVL 3RZDL 3S2DL 3GTGL 1WCML 3HOWL 2VUML 2B63L 1Y1WL 5M3ML 4BBRL 3K7AL 4A93L 5FJ8L 2JA5L 3FKIL 3M3YL 4C3HL 4QIWP 3S17L 3HOZL 3H0GL 3S2HL 5M5YL 4C3IL 3S1QL 5C3EL 2NVTL 5M3FL 3S1ML 3S1RL 4A3IL 5M5WL 3M4OL 3S1NL 3PO3L 4A3CL 3CQZL
chains in the Genus database with same CATH superfamily
2O5JD 3GTOL 1P7PA 1TWCL 2E2HL 2KKDA 1S24A 1PFYA 2JA8L 3S16L 3H9CA 2JA6L 2XJQA 1RDGA 4A3LL 3QVDA 1RB9A 2K2DA 2H12A 3MQKB 3LPEB 1DX8A 3RZOL 2YU9L 1TWHL 4GS7D 1VZHA 3SS2A 1Y1VL 1YV1A 3LWQB 4ME3A 3H99A 2XJUA 1S2ZA 2LCQA 1QYBA 3HJWB 5DM71 4AR5A 4BXXL 3I4ML 3S14L 1SMMA 1BE7A 1IRNA 4V196 3GTML 1WJVA 2JI2A 4A3EL 2A6HD 5IY0A 3S15L 2V3BB 6RXNA 3LWOB 3HOXL 1VCXA 2ZIXA 2PYAA 3S2DL 2GMGA 3J7Z1 2A6ED 2C6BA 1B2OA 4AR6A 4B8CD 5MFZA 3FKIL 4LHNA 1LTLA 1ODHA 1B71A 3KYXA 2M6OA 5M3FL 1SMUA 2ERJA 5MGNA 3PWFA 2V0EA 2RDVA 1C09A 4WFN1 3K35A 3B0AB 1B2JA 1DVBA 2CKCA 4C3JL 5H1Sc 2R93L 1TWAL 5AN9H 1ZRPA 3HAXC 5AI3A 1T9OA 5JVH1 3PIP1 4ZN1B 4JADA 1R0HA 4AI1A 1PFVA 2NVYL 2E2JL 4A3BL 2NVXL 3HJYB 3PO2L 3RZ6A 3PZAA 4XGHA 5IP9L 1RDVA 4BY7L 1BQ8A 5IYBL 5IYDL 4JAEA 3PIO1 2RFKB 3GTPL 2JI3A 4POGA 2PVXA 1I6HL 4AI2A 1NXEA 1QQTA 7RXNA 3IU3I 4A3GL 2AUSB 1FHMA 2PPTA 3PL5A 1T9PA 2CR8A 5MLC3 3A44A 3GTQL 1SMWA 5C44L 4A3KL 4JAFA 2M4VA 3LWRB 3PKJA 3GTGL 1WCML 4YWLA 4E6YA 5M3ML 1IU6A 3NFPI 1YUZA 1CADA 4RXNA 1PFWA 3M3YL 4QIWP 3S17L 1PZXA 2MS3A 3H0GL 3S2HL 5M5YL 2AYJA 1RYQA 4AHWA 1B13A 2NVTL 3S1ML 4AI0A 1Z92B 4AHXA 2HVYC 1T9QA 3I4NL 3MPSA 5DM61 5C4XL 2XJRA 2DSXA 1R0IA 3ZG6A 2R92L 1LKPA 2NVQL 1YUXA 5MFPA 1I3QL 5GAGc 2A69D 5C4JL 3QQCE 2V0FA 1IROA 5EIOC 4AHYA 1FHHA 3KYVA 3KYYA 3GTJL 2WB1P 4A3DL 4AYBP 2VL6A 1QCVA 4A3JL 5JVG1 1SFOL 1TWGL 2B5ID 4YWMA 2ERSA 4Y52L 1TWFL 3RZTA 3GTKL 1IW7D 4UY81 3H97A 3RYGA 2R7ZL 2JA7L 1NXGA 3HOYL 2NYDA 3LWPB 1IU5A 2XJPA 2Y0SP 1K83L 3JR7A 4XXBB 1R9TL 3HOUL 1BRFA 2C6AA 4POFA 2A68D 3HOVL 3KYWA 5GADc 3RZDL 2BE5D 1RYTA 3LWVB 2HR5A 2APOB 2Z3QB 4TVMA 4BBRL 2CKAA 5GAEc 3K7AL 1JYBA 4A93L 2AQCA 5GAHc 5FJ8L 2JA5L 3HOZL 4JAGA 1OWCA 1RWDA 5C3EL 3WWLA 2QL0A 1BFYA 4G6BA 3S1NL 1NNQA 2EY4E 1VZGA 3P8BA 5IYCL 4X6AL 1CAAA 4AR4A 3J7Y1 2PVEA 4BBSL 5FLML 1I50L 4AHZA 3GTLL 2PSMC 1R0FA 3P2AA 2J9UB 4BY1L 1YK4A 3H3VM 2WAQP 3KYUA 1E8JA 4LHLA 2M6PA 4U671 5K2ME 5IP7L 2XJVA 3HKZP 5M5XL 2XJSA 1LKOA 5MF6A 4Y7NL 1S30A 2E2IL 2PMZP 2Z3RB 4C2M1 1R0JA 4A3ML 4AR3A 1LKMA 5RXNA 3B08B 1PFUA 5AI2A 1VZIA 1OWBA 3MSUA 3PKIA 4A3FL 1R0GA 5EINC 3VPBE 8RXNA 4ZN3B 4AI3A 3HOWL 3WWNB 2VUML 4K9FA 2B63L 1Y1WL 3FDJA 1F4LA 2KN9A 1H7VA 1BQ9A 2L0ZA 2JI1A 3H9BA 4C3HL 1YK5A 3LNLA 2M4YA 4C3IL 3S1QL 3S1RL 4TPUA 4A3IL 5M5WL 3M4OL 4A3CL 3PO3L 3CQZL 2XJTA
chains in the Genus database with same CATH topology
3GTOL 5IYCL 1TWCL 3I4NL 2E2HL 5C4XL 4X6AL 2R92L 2JA8L 3S16L 4C3JL 2NVQL 2R93L 1TWAL 2JA6L 1I3QL 4A3LL 4BBSL 5C4JL 5FLML 1I50L 3GTLL 3RZOL 3GTJL 2WB1P 4A3DL 4BY1L 4AYBP 3H3VM 2WAQP 4A3JL 2YU9L 1TWHL 2NVYL 2E2JL 1Y1VL 4A3BL 2NVXL 1SFOL 1TWGL 5IP7L 3HKZP 5M5XL 3PO2L 5IP9L 4Y7NL 4Y52L 1TWFL 4BY7L 5IYBL 5IYDL 3GTKL 2E2IL 2PMZP 3GTPL 4BXXL 4C2M1 3I4ML 3S14L 4A3ML 2R7ZL 2JA7L 3HOYL 1I6HL 3GTML 2Y0SP 4A3GL 1K83L 4A3EL 1R9TL 3HOUL 4A3FL 3S15L 3GTQL 3HOXL 5C44L 4A3KL 3HOVL 3RZDL 3S2DL 3GTGL 1WCML 3HOWL 2VUML 2B63L 1Y1WL 5M3ML 4BBRL 3K7AL 4A93L 5FJ8L 2JA5L 3FKIL 3M3YL 4C3HL 4QIWP 3S17L 3HOZL 3H0GL 3S2HL 5M5YL 4C3IL 3S1QL 5C3EL 2NVTL 5M3FL 3S1ML 3S1RL 4A3IL 5M5WL 3M4OL 3S1NL 3PO3L 4A3CL 3CQZL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTO L;  5IYC L;  1TWC L;  3I4N L;  2E2H L;  5C4X L;  4X6A L;  2R92 L;  2JA8 L;  3S16 L;  4C3J L;  2NVQ L;  2R93 L;  1TWA L;  2JA6 L;  1I3Q L;  4A3L L;  4BBS L;  5C4J L;  5FLM L;  1I50 L;  3GTL L;  3RZO L;  3GTJ L;  2WB1 P;  4A3D L;  4BY1 L;  4AYB P;  3H3V M;  2WAQ P;  4A3J L;  2YU9 L;  1TWH L;  2NVY L;  2E2J L;  1Y1V L;  4A3B L;  2NVX L;  1SFO L;  1TWG L;  5IP7 L;  3HKZ P;  5M5X L;  3PO2 L;  5IP9 L;  4Y7N L;  4Y52 L;  1TWF L;  4BY7 L;  5IYB L;  5IYD L;  3GTK L;  2E2I L;  2PMZ P;  3GTP L;  4BXX L;  4C2M 1;  3I4M L;  3S14 L;  4A3M L;  2R7Z L;  2JA7 L;  3HOY L;  1I6H L;  3GTM L;  2Y0S P;  4A3G L;  1K83 L;  4A3E L;  1R9T L;  3HOU L;  4A3F L;  3S15 L;  3GTQ L;  3HOX L;  5C44 L;  4A3K L;  3HOV L;  3RZD L;  3S2D L;  3GTG L;  1WCM L;  3HOW L;  2VUM L;  2B63 L;  1Y1W L;  5M3M L;  4BBR L;  3K7A L;  4A93 L;  5FJ8 L;  2JA5 L;  3FKI L;  3M3Y L;  4C3H L;  4QIW P;  3S17 L;  3HOZ L;  3H0G L;  3S2H L;  5M5Y L;  4C3I L;  3S1Q L;  5C3E L;  2NVT L;  5M3F L;  3S1M L;  3S1R L;  4A3I L;  5M5W L;  3M4O L;  3S1N L;  3PO3 L;  4A3C L;  3CQZ L; 
#chains in the Genus database with same CATH topology
 2O5J D;  3GTO L;  1P7P A;  1TWC L;  2E2H L;  2KKD A;  1S24 A;  1PFY A;  2JA8 L;  3S16 L;  3H9C A;  2JA6 L;  2XJQ A;  1RDG A;  4A3L L;  3QVD A;  1RB9 A;  2K2D A;  2H12 A;  3MQK B;  3LPE B;  1DX8 A;  3RZO L;  2YU9 L;  1TWH L;  4GS7 D;  1VZH A;  3SS2 A;  1Y1V L;  1YV1 A;  3LWQ B;  4ME3 A;  3H99 A;  2XJU A;  1S2Z A;  2LCQ A;  1QYB A;  3HJW B;  5DM7 1;  4AR5 A;  4BXX L;  3I4M L;  3S14 L;  1SMM A;  1BE7 A;  1IRN A;  4V19 6;  3GTM L;  1WJV A;  2JI2 A;  4A3E L;  2A6H D;  5IY0 A;  3S15 L;  2V3B B;  6RXN A;  3LWO B;  3HOX L;  1VCX A;  2ZIX A;  2PYA A;  3S2D L;  2GMG A;  3J7Z 1;  2A6E D;  2C6B A;  1B2O A;  4AR6 A;  4B8C D;  5MFZ A;  3FKI L;  4LHN A;  1LTL A;  1ODH A;  1B71 A;  3KYX A;  2M6O A;  5M3F L;  1SMU A;  2ERJ A;  5MGN A;  3PWF A;  2V0E A;  2RDV A;  1C09 A;  4WFN 1;  3K35 A;  3B0A B;  1B2J A;  1DVB A;  2CKC A;  4C3J L;  5H1S c;  2R93 L;  1TWA L;  5AN9 H;  1ZRP A;  3HAX C;  5AI3 A;  1T9O A;  5JVH 1;  3PIP 1;  4ZN1 B;  4JAD A;  1R0H A;  4AI1 A;  1PFV A;  2NVY L;  2E2J L;  4A3B L;  2NVX L;  3HJY B;  3PO2 L;  3RZ6 A;  3PZA A;  4XGH A;  5IP9 L;  1RDV A;  4BY7 L;  1BQ8 A;  5IYB L;  5IYD L;  4JAE A;  3PIO 1;  2RFK B;  3GTP L;  2JI3 A;  4POG A;  2PVX A;  1I6H L;  4AI2 A;  1NXE A;  1QQT A;  7RXN A;  3IU3 I;  4A3G L;  2AUS B;  1FHM A;  2PPT A;  3PL5 A;  1T9P A;  2CR8 A;  5MLC 3;  3A44 A;  3GTQ L;  1SMW A;  5C44 L;  4A3K L;  4JAF A;  2M4V A;  3LWR B;  3PKJ A;  3GTG L;  1WCM L;  4YWL A;  4E6Y A;  5M3M L;  1IU6 A;  3NFP I;  1YUZ A;  1CAD A;  4RXN A;  1PFW A;  3M3Y L;  4QIW P;  3S17 L;  1PZX A;  2MS3 A;  3H0G L;  3S2H L;  5M5Y L;  2AYJ A;  1RYQ A;  4AHW A;  1B13 A;  2NVT L;  3S1M L;  4AI0 A;  1Z92 B;  4AHX A;  2HVY C;  1T9Q A;  3I4N L;  3MPS A;  5DM6 1;  5C4X L;  2XJR A;  2DSX A;  1R0I A;  3ZG6 A;  2R92 L;  1LKP A;  2NVQ L;  1YUX A;  5MFP A;  1I3Q L;  5GAG c;  2A69 D;  5C4J L;  3QQC E;  2V0F A;  1IRO A;  5EIO C;  4AHY A;  1FHH A;  3KYV A;  3KYY A;  3GTJ L;  2WB1 P;  4A3D L;  4AYB P;  2VL6 A;  1QCV A;  4A3J L;  5JVG 1;  1SFO L;  1TWG L;  2B5I D;  4YWM A;  2ERS A;  4Y52 L;  1TWF L;  3RZT A;  3GTK L;  1IW7 D;  4UY8 1;  3H97 A;  3RYG A;  2R7Z L;  2JA7 L;  1NXG A;  3HOY L;  2NYD A;  3LWP B;  1IU5 A;  2XJP A;  2Y0S P;  1K83 L;  3JR7 A;  4XXB B;  1R9T L;  3HOU L;  1BRF A;  2C6A A;  4POF A;  2A68 D;  3HOV L;  3KYW A;  5GAD c;  3RZD L;  2BE5 D;  1RYT A;  3LWV B;  2HR5 A;  2APO B;  2Z3Q B;  4TVM A;  4BBR L;  2CKA A;  5GAE c;  3K7A L;  1JYB A;  4A93 L;  2AQC A;  5GAH c;  5FJ8 L;  2JA5 L;  3HOZ L;  4JAG A;  1OWC A;  1RWD A;  5C3E L;  3WWL A;  2QL0 A;  1BFY A;  4G6B A;  3S1N L;  1NNQ A;  2EY4 E;  1VZG A;  3P8B A;  5IYC L;  4X6A L;  1CAA A;  4AR4 A;  3J7Y 1;  2PVE A;  4BBS L;  5FLM L;  1I50 L;  4AHZ A;  3GTL L;  2PSM C;  1R0F A;  3P2A A;  2J9U B;  4BY1 L;  1YK4 A;  3H3V M;  2WAQ P;  3KYU A;  1E8J A;  4LHL A;  2M6P A;  4U67 1;  5K2M E;  5IP7 L;  2XJV A;  3HKZ P;  5M5X L;  2XJS A;  1LKO A;  5MF6 A;  4Y7N L;  1S30 A;  2E2I L;  2PMZ P;  2Z3R B;  4C2M 1;  1R0J A;  4A3M L;  4AR3 A;  1LKM A;  5RXN A;  3B08 B;  1PFU A;  5AI2 A;  1VZI A;  1OWB A;  3MSU A;  3PKI A;  4A3F L;  1R0G A;  5EIN C;  3VPB E;  8RXN A;  4ZN3 B;  4AI3 A;  3HOW L;  3WWN B;  2VUM L;  4K9F A;  2B63 L;  1Y1W L;  3FDJ A;  1F4L A;  2KN9 A;  1H7V A;  1BQ9 A;  2L0Z A;  2JI1 A;  3H9B A;  4C3H L;  1YK5 A;  3LNL A;  2M4Y A;  4C3I L;  3S1Q L;  3S1R L;  4TPU A;  4A3I L;  5M5W L;  3M4O L;  4A3C L;  3PO3 L;  3CQZ L;  2XJT A; 
#chains in the Genus database with same CATH homology
 3GTO L;  5IYC L;  1TWC L;  3I4N L;  2E2H L;  5C4X L;  4X6A L;  2R92 L;  2JA8 L;  3S16 L;  4C3J L;  2NVQ L;  2R93 L;  1TWA L;  2JA6 L;  1I3Q L;  4A3L L;  4BBS L;  5C4J L;  5FLM L;  1I50 L;  3GTL L;  3RZO L;  3GTJ L;  2WB1 P;  4A3D L;  4BY1 L;  4AYB P;  3H3V M;  2WAQ P;  4A3J L;  2YU9 L;  1TWH L;  2NVY L;  2E2J L;  1Y1V L;  4A3B L;  2NVX L;  1SFO L;  1TWG L;  5IP7 L;  3HKZ P;  5M5X L;  3PO2 L;  5IP9 L;  4Y7N L;  4Y52 L;  1TWF L;  4BY7 L;  5IYB L;  5IYD L;  3GTK L;  2E2I L;  2PMZ P;  3GTP L;  4BXX L;  4C2M 1;  3I4M L;  3S14 L;  4A3M L;  2R7Z L;  2JA7 L;  3HOY L;  1I6H L;  3GTM L;  2Y0S P;  4A3G L;  1K83 L;  4A3E L;  1R9T L;  3HOU L;  4A3F L;  3S15 L;  3GTQ L;  3HOX L;  5C44 L;  4A3K L;  3HOV L;  3RZD L;  3S2D L;  3GTG L;  1WCM L;  3HOW L;  2VUM L;  2B63 L;  1Y1W L;  5M3M L;  4BBR L;  3K7A L;  4A93 L;  5FJ8 L;  2JA5 L;  3FKI L;  3M3Y L;  4C3H L;  4QIW P;  3S17 L;  3HOZ L;  3H0G L;  3S2H L;  5M5Y L;  4C3I L;  3S1Q L;  5C3E L;  2NVT L;  5M3F L;  3S1M L;  3S1R L;  4A3I L;  5M5W L;  3M4O L;  3S1N L;  3PO3 L;  4A3C L;  3CQZ L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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