2R7ZL

Cisplatin lesion containing rna polymerase ii elongation complex
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of transcriptional stalling at cisplatin-damaged DNA.
pubmed doi rcsb
molecule tags Transcription/dna-rna hybrid
molecule keywords 5'-D(*TP*AP*CP*TP*TP*GUP*CP*CP*CP*TP*CP*CP*TP*CP*AP*T)-3'
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2007-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2r7zL00
3HOZL 4AYBP 1TWAL 3GTML 4A3DL 4C3JL 3S1NL 5M3ML 4BXXL 2WB1P 3H0GL 4A3KL 4A3IL 2JA8L 4A3JL 4X6AL 2WAQP 4BY7L 5M3FL 3PO2L 4A3LL 1R9TL 1TWFL 3HOXL 3PO3L 2JA5L 3GTGL 5FLML 3RZDL 3S14L 4A3BL 2NVYL 3S17L 3GTOL 2R92L 4Y52L 1Y1WL 2VUML 2YU9L 5M5YL 3HOUL 3HOYL 1K83L 5IP9L 1TWCL 4A3CL 3I4NL 5IYBL 5FJ8L 5C44L 5M5WL 3FKIL 1I50L 2E2JL 4BBRL 4BY1L 4A3EL 3S2HL 4C3IL 5C4JL 5M5XL 5C3EL 2JA6L 3H3VM 2E2HL 3CQZL 3RZOL 3S1QL 3GTJL 2JA7L 1TWGL 5IYCL 3GTKL 2Y0SP 3M4OL 4QIWP 2PMZP 1Y1VL 2NVTL 5IYDL 3S1RL 4C2M1 4C3HL 3S15L 3M3YL 2NVXL 2B63L 1I3QL 2NVQL 4A3GL 1I6HL 4A3ML 3HOVL 4Y7NL 5IP7L 3S16L 3K7AL 4A93L 3S1ML 1SFOL 1WCML 3GTQL 2E2IL 3HKZP 3GTPL 3GTLL 3S2DL 3HOWL 3I4ML 2R93L 4BBSL 1TWHL 2R7ZL 5C4XL 4A3FL
chains in the Genus database with same CATH superfamily
5DM71 3HOZL 5MFZA 3LWOB 5EINC 1LKOA 1QQTA 4POFA 5M3ML 1RB9A 4TVMA 2JA8L 3LWPB 3VPBE 2A6ED 3H97A 2JA5L 3GTGL 5FLML 3S14L 1E8JA 4GS7D 1DVBA 3JR7A 3HJYB 4AHWA 1Y1WL 4E6YA 2C6AA 4JAGA 2PPTA 3NFPI 4A3CL 1Z92B 5C44L 5M5WL 3LWRB 3FKIL 2E2JL 4BY1L 5JVG1 1ODHA 4C3IL 5M5XL 1P7PA 4G6BA 2JA6L 3H3VM 3CQZL 3GTJL 2M4VA 5IYCL 2PVXA 1LKPA 2M4YA 2XJQA 4AR5A 4JAFA 2NVXL 2B63L 5H1Sc 1LKMA 1I3QL 2MS3A 4A3GL 1YUXA 1F4LA 1I6HL 4A3ML 4JAEA 2XJPA 1BQ9A 5DM61 2NYDA 4ZN3B 3J7Z1 3MPSA 3RZTA 3S1ML 1WCML 3GTQL 2Z3RB 3HOWL 1YV1A 5AN9H 3IU3I 1ZRPA 4BBSL 4AR3A 5MLC3 1IROA 1JYBA 5RXNA 1YUZA 4A3DL 4AI2A 2ERSA 3PKIA 2M6OA 2M6PA 4BXXL 3H0GL 3WWNB 4AI3A 2AQCA 4A3JL 1RYTA 2A69D 4RXNA 3P8BA 4BY7L 2XJUA 1WJVA 3HOXL 1R0HA 2L0ZA 1S2ZA 1S30A 3RZDL 3H9BA 2NVYL 2AYJA 3S17L 1FHMA 2R92L 1VCXA 4U671 3H9CA 1VZGA 5IP9L 3I4NL 2LCQA 1PZXA 4TPUA 5FJ8L 4LHLA 3P2AA 1VZIA 8RXNA 2KN9A 4A3EL 1PFYA 4JADA 3S2HL 2BE5D 5C3EL 1R0GA 2E2HL 1T9OA 3S1QL 2CR8A 5MFPA 3LWQB 5IY0A 1T9PA 2RFKB 1TWGL 3GTKL 5MGNA 1NNQA 1IW7D 1PFUA 2PMZP 1DX8A 1Y1VL 4XXBB 1C09A 1FHHA 4C2M1 4C3HL 3M3YL 2XJRA 3LWVB 3KYUA 4YWLA 2NVQL 1IRNA 4Y7NL 2JI1A 5IP7L 3HJWB 3MSUA 1R0JA 3S2DL 2R7ZL 2V3BB 4AYBP 4AHYA 4C3JL 3ZG6A 1YK5A 3WWLA 4XGHA 3RYGA 3A44A 3B08B 2Z3QB 4B8CD 2HVYC 2WAQP 1NXGA 1BQ8A 3PO2L 4A3LL 4WFN1 1R9TL 1TWFL 2JI2A 3PO3L 1BRFA 2EY4E 1PFVA 2K2DA 3H99A 3GTOL 5GAEc 4Y52L 4YWMA 2YU9L 3HOUL 3PWFA 1TWCL 3J7Y1 5IYBL 1RYQA 1CADA 3QVDA 1CAAA 3QQCE 5C4JL 1NXEA 4AR6A 2XJVA 2JA7L 1IU5A 2H12A 2APOB 1SMUA 3M4OL 1RDVA 1S24A 2NVTL 4AR4A 2J9UB 4UY81 3PIP1 1R0IA 1RDGA 3PIO1 3HOVL 2QL0A 4POGA 2JI3A 1B71A 2VL6A 4AHZA 3FDJA 1B2JA 3K7AL 4A93L 2KKDA 3GTPL 3HKZP 3KYWA 3GTLL 2PYAA 2B5ID 1RWDA 1B2OA 5C4XL 4A3FL 2CKCA 2ZIXA 1TWAL 3GTML 1BE7A 3PL5A 3MQKB 3S1NL 2A6HD 5GADc 2XJTA 1QYBA 5MF6A 2WB1P 2PSMC 4A3KL 4A3IL 1T9QA 3LNLA 4X6AL 5M3FL 1IU6A 4ZN1B 2V0EA 3K35A 1R0FA 2PVEA 3KYVA 2CKAA 4A3BL 2A68D 4K9FA 2V0FA 2VUML 5M5YL 3HOYL 1LTLA 1K83L 4V196 3PKJA 2GMGA 1SMWA 3SS2A 2XJSA 5K2ME 5GAHc 5GAGc 1I50L 2AUSB 4BBRL 4AHXA 2O5JD 5JVH1 3PZAA 5AI3A 3RZOL 2C6BA 2RDVA 2Y0SP 1YK4A 4LHNA 4QIWP 1OWCA 3B0AB 5IYDL 3S1RL 3S15L 1BFYA 3RZ6A 6RXNA 2ERJA 7RXNA 4AI1A 1H7VA 5AI2A 1VZHA 3HAXC 1OWBA 1PFWA 3KYYA 1B13A 3S16L 4AI0A 1SFOL 5EIOC 2E2IL 3LPEB 1QCVA 3I4ML 2R93L 3KYXA 2HR5A 1TWHL 1SMMA 4ME3A 2DSXA
chains in the Genus database with same CATH topology
3HOZL 4AYBP 1TWAL 3GTML 4A3DL 4C3JL 3S1NL 5M3ML 4BXXL 2WB1P 3H0GL 4A3KL 4A3IL 2JA8L 4A3JL 4X6AL 2WAQP 4BY7L 5M3FL 3PO2L 4A3LL 1R9TL 1TWFL 3HOXL 3PO3L 2JA5L 3GTGL 5FLML 3RZDL 3S14L 4A3BL 2NVYL 3S17L 3GTOL 2R92L 4Y52L 1Y1WL 2VUML 2YU9L 5M5YL 3HOUL 3HOYL 1K83L 5IP9L 1TWCL 4A3CL 3I4NL 5IYBL 5FJ8L 5C44L 5M5WL 3FKIL 1I50L 2E2JL 4BBRL 4BY1L 4A3EL 3S2HL 4C3IL 5C4JL 5M5XL 5C3EL 2JA6L 3H3VM 2E2HL 3CQZL 3RZOL 3S1QL 3GTJL 2JA7L 1TWGL 5IYCL 3GTKL 2Y0SP 3M4OL 4QIWP 2PMZP 1Y1VL 2NVTL 5IYDL 3S1RL 4C2M1 4C3HL 3S15L 3M3YL 2NVXL 2B63L 1I3QL 2NVQL 4A3GL 1I6HL 4A3ML 3HOVL 4Y7NL 5IP7L 3S16L 3K7AL 4A93L 3S1ML 1SFOL 1WCML 3GTQL 2E2IL 3HKZP 3GTPL 3GTLL 3S2DL 3HOWL 3I4ML 2R93L 4BBSL 1TWHL 2R7ZL 5C4XL 4A3FL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HOZ L;  4AYB P;  1TWA L;  3GTM L;  4A3D L;  4C3J L;  3S1N L;  5M3M L;  4BXX L;  2WB1 P;  3H0G L;  4A3K L;  4A3I L;  2JA8 L;  4A3J L;  4X6A L;  2WAQ P;  4BY7 L;  5M3F L;  3PO2 L;  4A3L L;  1R9T L;  1TWF L;  3HOX L;  3PO3 L;  2JA5 L;  3GTG L;  5FLM L;  3RZD L;  3S14 L;  4A3B L;  2NVY L;  3S17 L;  3GTO L;  2R92 L;  4Y52 L;  1Y1W L;  2VUM L;  2YU9 L;  5M5Y L;  3HOU L;  3HOY L;  1K83 L;  5IP9 L;  1TWC L;  4A3C L;  3I4N L;  5IYB L;  5FJ8 L;  5C44 L;  5M5W L;  3FKI L;  1I50 L;  2E2J L;  4BBR L;  4BY1 L;  4A3E L;  3S2H L;  4C3I L;  5C4J L;  5M5X L;  5C3E L;  2JA6 L;  3H3V M;  2E2H L;  3CQZ L;  3RZO L;  3S1Q L;  3GTJ L;  2JA7 L;  1TWG L;  5IYC L;  3GTK L;  2Y0S P;  3M4O L;  4QIW P;  2PMZ P;  1Y1V L;  2NVT L;  5IYD L;  3S1R L;  4C2M 1;  4C3H L;  3S15 L;  3M3Y L;  2NVX L;  2B63 L;  1I3Q L;  2NVQ L;  4A3G L;  1I6H L;  4A3M L;  3HOV L;  4Y7N L;  5IP7 L;  3S16 L;  3K7A L;  4A93 L;  3S1M L;  1SFO L;  1WCM L;  3GTQ L;  2E2I L;  3HKZ P;  3GTP L;  3GTL L;  3S2D L;  3HOW L;  3I4M L;  2R93 L;  4BBS L;  1TWH L;  2R7Z L;  5C4X L;  4A3F L; 
#chains in the Genus database with same CATH topology
 5DM7 1;  3HOZ L;  5MFZ A;  3LWO B;  5EIN C;  1LKO A;  1QQT A;  4POF A;  5M3M L;  1RB9 A;  4TVM A;  2JA8 L;  3LWP B;  3VPB E;  2A6E D;  3H97 A;  2JA5 L;  3GTG L;  5FLM L;  3S14 L;  1E8J A;  4GS7 D;  1DVB A;  3JR7 A;  3HJY B;  4AHW A;  1Y1W L;  4E6Y A;  2C6A A;  4JAG A;  2PPT A;  3NFP I;  4A3C L;  1Z92 B;  5C44 L;  5M5W L;  3LWR B;  3FKI L;  2E2J L;  4BY1 L;  5JVG 1;  1ODH A;  4C3I L;  5M5X L;  1P7P A;  4G6B A;  2JA6 L;  3H3V M;  3CQZ L;  3GTJ L;  2M4V A;  5IYC L;  2PVX A;  1LKP A;  2M4Y A;  2XJQ A;  4AR5 A;  4JAF A;  2NVX L;  2B63 L;  5H1S c;  1LKM A;  1I3Q L;  2MS3 A;  4A3G L;  1YUX A;  1F4L A;  1I6H L;  4A3M L;  4JAE A;  2XJP A;  1BQ9 A;  5DM6 1;  2NYD A;  4ZN3 B;  3J7Z 1;  3MPS A;  3RZT A;  3S1M L;  1WCM L;  3GTQ L;  2Z3R B;  3HOW L;  1YV1 A;  5AN9 H;  3IU3 I;  1ZRP A;  4BBS L;  4AR3 A;  5MLC 3;  1IRO A;  1JYB A;  5RXN A;  1YUZ A;  4A3D L;  4AI2 A;  2ERS A;  3PKI A;  2M6O A;  2M6P A;  4BXX L;  3H0G L;  3WWN B;  4AI3 A;  2AQC A;  4A3J L;  1RYT A;  2A69 D;  4RXN A;  3P8B A;  4BY7 L;  2XJU A;  1WJV A;  3HOX L;  1R0H A;  2L0Z A;  1S2Z A;  1S30 A;  3RZD L;  3H9B A;  2NVY L;  2AYJ A;  3S17 L;  1FHM A;  2R92 L;  1VCX A;  4U67 1;  3H9C A;  1VZG A;  5IP9 L;  3I4N L;  2LCQ A;  1PZX A;  4TPU A;  5FJ8 L;  4LHL A;  3P2A A;  1VZI A;  8RXN A;  2KN9 A;  4A3E L;  1PFY A;  4JAD A;  3S2H L;  2BE5 D;  5C3E L;  1R0G A;  2E2H L;  1T9O A;  3S1Q L;  2CR8 A;  5MFP A;  3LWQ B;  5IY0 A;  1T9P A;  2RFK B;  1TWG L;  3GTK L;  5MGN A;  1NNQ A;  1IW7 D;  1PFU A;  2PMZ P;  1DX8 A;  1Y1V L;  4XXB B;  1C09 A;  1FHH A;  4C2M 1;  4C3H L;  3M3Y L;  2XJR A;  3LWV B;  3KYU A;  4YWL A;  2NVQ L;  1IRN A;  4Y7N L;  2JI1 A;  5IP7 L;  3HJW B;  3MSU A;  1R0J A;  3S2D L;  2R7Z L;  2V3B B;  4AYB P;  4AHY A;  4C3J L;  3ZG6 A;  1YK5 A;  3WWL A;  4XGH A;  3RYG A;  3A44 A;  3B08 B;  2Z3Q B;  4B8C D;  2HVY C;  2WAQ P;  1NXG A;  1BQ8 A;  3PO2 L;  4A3L L;  4WFN 1;  1R9T L;  1TWF L;  2JI2 A;  3PO3 L;  1BRF A;  2EY4 E;  1PFV A;  2K2D A;  3H99 A;  3GTO L;  5GAE c;  4Y52 L;  4YWM A;  2YU9 L;  3HOU L;  3PWF A;  1TWC L;  3J7Y 1;  5IYB L;  1RYQ A;  1CAD A;  3QVD A;  1CAA A;  3QQC E;  5C4J L;  1NXE A;  4AR6 A;  2XJV A;  2JA7 L;  1IU5 A;  2H12 A;  2APO B;  1SMU A;  3M4O L;  1RDV A;  1S24 A;  2NVT L;  4AR4 A;  2J9U B;  4UY8 1;  3PIP 1;  1R0I A;  1RDG A;  3PIO 1;  3HOV L;  2QL0 A;  4POG A;  2JI3 A;  1B71 A;  2VL6 A;  4AHZ A;  3FDJ A;  1B2J A;  3K7A L;  4A93 L;  2KKD A;  3GTP L;  3HKZ P;  3KYW A;  3GTL L;  2PYA A;  2B5I D;  1RWD A;  1B2O A;  5C4X L;  4A3F L;  2CKC A;  2ZIX A;  1TWA L;  3GTM L;  1BE7 A;  3PL5 A;  3MQK B;  3S1N L;  2A6H D;  5GAD c;  2XJT A;  1QYB A;  5MF6 A;  2WB1 P;  2PSM C;  4A3K L;  4A3I L;  1T9Q A;  3LNL A;  4X6A L;  5M3F L;  1IU6 A;  4ZN1 B;  2V0E A;  3K35 A;  1R0F A;  2PVE A;  3KYV A;  2CKA A;  4A3B L;  2A68 D;  4K9F A;  2V0F A;  2VUM L;  5M5Y L;  3HOY L;  1LTL A;  1K83 L;  4V19 6;  3PKJ A;  2GMG A;  1SMW A;  3SS2 A;  2XJS A;  5K2M E;  5GAH c;  5GAG c;  1I50 L;  2AUS B;  4BBR L;  4AHX A;  2O5J D;  5JVH 1;  3PZA A;  5AI3 A;  3RZO L;  2C6B A;  2RDV A;  2Y0S P;  1YK4 A;  4LHN A;  4QIW P;  1OWC A;  3B0A B;  5IYD L;  3S1R L;  3S15 L;  1BFY A;  3RZ6 A;  6RXN A;  2ERJ A;  7RXN A;  4AI1 A;  1H7V A;  5AI2 A;  1VZH A;  3HAX C;  1OWB A;  1PFW A;  3KYY A;  1B13 A;  3S16 L;  4AI0 A;  1SFO L;  5EIO C;  2E2I L;  3LPE B;  1QCV A;  3I4M L;  2R93 L;  3KYX A;  2HR5 A;  1TWH L;  1SMM A;  4ME3 A;  2DSX A; 
#chains in the Genus database with same CATH homology
 3HOZ L;  4AYB P;  1TWA L;  3GTM L;  4A3D L;  4C3J L;  3S1N L;  5M3M L;  4BXX L;  2WB1 P;  3H0G L;  4A3K L;  4A3I L;  2JA8 L;  4A3J L;  4X6A L;  2WAQ P;  4BY7 L;  5M3F L;  3PO2 L;  4A3L L;  1R9T L;  1TWF L;  3HOX L;  3PO3 L;  2JA5 L;  3GTG L;  5FLM L;  3RZD L;  3S14 L;  4A3B L;  2NVY L;  3S17 L;  3GTO L;  2R92 L;  4Y52 L;  1Y1W L;  2VUM L;  2YU9 L;  5M5Y L;  3HOU L;  3HOY L;  1K83 L;  5IP9 L;  1TWC L;  4A3C L;  3I4N L;  5IYB L;  5FJ8 L;  5C44 L;  5M5W L;  3FKI L;  1I50 L;  2E2J L;  4BBR L;  4BY1 L;  4A3E L;  3S2H L;  4C3I L;  5C4J L;  5M5X L;  5C3E L;  2JA6 L;  3H3V M;  2E2H L;  3CQZ L;  3RZO L;  3S1Q L;  3GTJ L;  2JA7 L;  1TWG L;  5IYC L;  3GTK L;  2Y0S P;  3M4O L;  4QIW P;  2PMZ P;  1Y1V L;  2NVT L;  5IYD L;  3S1R L;  4C2M 1;  4C3H L;  3S15 L;  3M3Y L;  2NVX L;  2B63 L;  1I3Q L;  2NVQ L;  4A3G L;  1I6H L;  4A3M L;  3HOV L;  4Y7N L;  5IP7 L;  3S16 L;  3K7A L;  4A93 L;  3S1M L;  1SFO L;  1WCM L;  3GTQ L;  2E2I L;  3HKZ P;  3GTP L;  3GTL L;  3S2D L;  3HOW L;  3I4M L;  2R93 L;  4BBS L;  1TWH L;  2R7Z L;  5C4X L;  4A3F L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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