2NVTL

Rna polymerase ii elongation complex in 150 mm mg+2 with gmpcpp
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule keywords 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3'
molecule tags Transcription,transferase/dna-rna hybrid
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2006-11-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2nvtL00
4BXXL 1TWFL 2NVTL 3PO3L 4X6AL 3CQZL 4C3HL 5FJ8L 3GTLL 4Y7NL 5IYDL 3S2HL 4AYBP 3S2DL 2WB1P 4A93L 5M3ML 3S1ML 3M3YL 5IP7L 4A3CL 5M5WL 3S17L 3M4OL 3RZOL 3HOXL 3FKIL 3GTML 3S1QL 2WAQP 1Y1VL 2R7ZL 2JA5L 5C4JL 1TWAL 3I4NL 1SFOL 1TWGL 4BBSL 3GTKL 5M5XL 3HOVL 2PMZP 2R92L 3H3VM 1I6HL 4BBRL 2JA6L 1K83L 4C3JL 3GTQL 2JA7L 2NVYL 3HOUL 4A3KL 1TWCL 4A3DL 3S15L 5FLML 4A3EL 3S1NL 3GTOL 5C3EL 1I50L 4QIWP 3S1RL 5C4XL 2VUML 3GTGL 1WCML 2Y0SP 5M3FL 3PO2L 3H0GL 2NVQL 4C2M1 3RZDL 4A3ML 4A3GL 4A3BL 5IYCL 4A3LL 4BY1L 2E2HL 3HOWL 3HKZP 2YU9L 2B63L 1Y1WL 3HOYL 3HOZL 4A3FL 3I4ML 2NVXL 3GTJL 1TWHL 2E2JL 2JA8L 3S14L 4Y52L 1I3QL 4C3IL 1R9TL 5C44L 3S16L 3GTPL 5IYBL 4BY7L 2E2IL 5M5YL 4A3JL 5IP9L 2R93L 4A3IL 3K7AL
chains in the Genus database with same CATH superfamily
1PFWA 3P2AA 3HJWB 1RYQA 5MGNA 4C3HL 5FJ8L 3H97A 3LPEB 4TPUA 3J7Z1 1IRNA 2Z3RB 2WB1P 5M3ML 2ERJA 3PZAA 1QCVA 1NXEA 4ME3A 2RFKB 3S17L 2AUSB 1SMWA 3HOXL 1PFYA 3FKIL 3S1QL 4JAEA 2WAQP 2R7ZL 2PVXA 2CKAA 2JI2A 3IU3I 4JAFA 2JI1A 3GTKL 5M5XL 3HOVL 1BE7A 2PMZP 3H3VM 2JA6L 1K83L 1IU5A 4AR5A 1QYBA 1SMUA 4ZN1B 3S1NL 2KN9A 3S1RL 5C4XL 5EIOC 3GTGL 1WCML 1R0GA 2A68D 3HOWL 3FDJA 2HR5A 5JVG1 1Y1WL 1VZGA 3PIP1 1SMMA 5GAHc 4XGHA 2XJSA 3PKJA 4RXNA 1QQTA 3LWQB 3MSUA 1I3QL 1R0HA 4AHWA 1OWCA 1R9TL 4AR3A 5C44L 5MFPA 3GTPL 4K9FA 3LWVB 3S16L 4BY7L 3JR7A 4TVMA 2PSMC 1FHMA 3LNLA 3K7AL 2XJTA 1CAAA 4AR6A 1RDGA 1B13A 1PFVA 1R0IA 4GS7D 5IYDL 4Y7NL 4AYBP 1YK5A 5M5WL 1BQ8A 1PFUA 2ERSA 2PYAA 5DM61 3LWPB 1Y1VL 3KYYA 4UY81 2XJVA 1SFOL 1S2ZA 1TWGL 3LWOB 4POGA 1I6HL 4BBRL 2L0ZA 2XJUA 4C3JL 3GTQL 2JA7L 2NVYL 2QL0A 1B2JA 3VPBE 5FLML 5K2ME 1RWDA 4A3EL 5RXNA 1ODHA 1E8JA 4LHLA 3HJYB 3H99A 3B08B 2VUML 1YUZA 2Y0SP 4B8CD 1NXGA 3PWFA 2NVQL 3HAXC 4C2M1 3RZDL 3ZG6A 2V0FA 4A3BL 2XJQA 2BE5D 2LCQA 2DSXA 1S24A 1YUXA 2B63L 2YU9L 1BFYA 5DM71 4WFN1 2A6ED 2K2DA 2V0EA 2NVXL 4V196 1Z92B 2JI3A 1C09A 3RZ6A 4YWLA 1TWHL 5GAGc 3RYGA 2JA8L 3S14L 4Y52L 5GAEc 4U671 4AHXA 2M4VA 5IYBL 5H1Sc 2ZIXA 4A3JL 7RXNA 2R93L 2Z3QB 4XXBB 4BXXL 1DVBA 2EY4E 3KYUA 4X6AL 3PO3L 3CQZL 3MQKB 5MLC3 3QQCE 4A93L 1F4LA 3S1ML 1VCXA 3M3YL 5IP7L 4A3CL 1RYTA 3M4OL 3RZOL 1OWBA 3GTML 4YWMA 2JA5L 4AI1A 3H9CA 1T9QA 5MFZA 5IY0A 2A6HD 4AI0A 5JVH1 2R92L 2MS3A 3KYXA 5AI2A 4JAGA 1VZIA 3MPSA 2NYDA 4POFA 3LWRB 3HOUL 4A3KL 1B71A 4A3DL 4AHZA 1T9PA 3GTOL 1I50L 3PIO1 2AYJA 5AI3A 8RXNA 2J9UB 4AI3A 4JADA 5M3FL 3H0GL 1S30A 1LKMA 4A3GL 5IYCL 4A3LL 2E2HL 2KKDA 2M6PA 3HKZP 1WJVA 3HOYL 3PKIA 1VZHA 3I4ML 5EINC 1LKOA 1BQ9A 2M4YA 1YV1A 3WWLA 1LTLA 1IU6A 2GMGA 1CADA 2RDVA 2E2IL 1YK4A 4AHYA 5MF6A 2CR8A 3K35A 2PPTA 2V3BB 1TWFL 1RB9A 2NVTL 2APOB 3GTLL 4LHNA 5AN9H 3S2HL 3S2DL 6RXNA 2C6BA 2HVYC 3SS2A 4AI2A 2M6OA 3KYWA 5C4JL 1TWAL 1B2OA 4G6BA 3I4NL 4BBSL 2B5ID 2VL6A 1H7VA 3P8BA 1JYBA 1NNQA 3QVDA 3KYVA 2H12A 1T9OA 1TWCL 2XJPA 2A69D 3J7Y1 3S15L 1P7PA 3A44A 5C3EL 4QIWP 1DX8A 1RDVA 3RZTA 2C6AA 4ZN3B 3PO2L 3H9BA 4A3ML 1FHHA 1PZXA 4AR4A 3B0AB 1R0JA 4BY1L 1BRFA 1ZRPA 1R0FA 3HOZL 4A3FL 1LKPA 1IROA 3GTJL 2E2JL 2CKCA 2O5JD 4C3IL 1IW7D 2PVEA 3WWNB 3NFPI 2AQCA 3PL5A 4E6YA 5M5YL 5IP9L 2XJRA 4A3IL 5GADc
chains in the Genus database with same CATH topology
4BXXL 1TWFL 2NVTL 3PO3L 4X6AL 3CQZL 4C3HL 5FJ8L 3GTLL 4Y7NL 5IYDL 3S2HL 4AYBP 3S2DL 2WB1P 4A93L 5M3ML 3S1ML 3M3YL 5IP7L 4A3CL 5M5WL 3S17L 3M4OL 3RZOL 3HOXL 3FKIL 3GTML 3S1QL 2WAQP 1Y1VL 2R7ZL 2JA5L 5C4JL 1TWAL 3I4NL 1SFOL 1TWGL 4BBSL 3GTKL 5M5XL 3HOVL 2PMZP 2R92L 3H3VM 1I6HL 4BBRL 2JA6L 1K83L 4C3JL 3GTQL 2JA7L 2NVYL 3HOUL 4A3KL 1TWCL 4A3DL 3S15L 5FLML 4A3EL 3S1NL 3GTOL 5C3EL 1I50L 4QIWP 3S1RL 5C4XL 2VUML 3GTGL 1WCML 2Y0SP 5M3FL 3PO2L 3H0GL 2NVQL 4C2M1 3RZDL 4A3ML 4A3GL 4A3BL 5IYCL 4A3LL 4BY1L 2E2HL 3HOWL 3HKZP 2YU9L 2B63L 1Y1WL 3HOYL 3HOZL 4A3FL 3I4ML 2NVXL 3GTJL 1TWHL 2E2JL 2JA8L 3S14L 4Y52L 1I3QL 4C3IL 1R9TL 5C44L 3S16L 3GTPL 5IYBL 4BY7L 2E2IL 5M5YL 4A3JL 5IP9L 2R93L 4A3IL 3K7AL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BXX L;  1TWF L;  2NVT L;  3PO3 L;  4X6A L;  3CQZ L;  4C3H L;  5FJ8 L;  3GTL L;  4Y7N L;  5IYD L;  3S2H L;  4AYB P;  3S2D L;  2WB1 P;  4A93 L;  5M3M L;  3S1M L;  3M3Y L;  5IP7 L;  4A3C L;  5M5W L;  3S17 L;  3M4O L;  3RZO L;  3HOX L;  3FKI L;  3GTM L;  3S1Q L;  2WAQ P;  1Y1V L;  2R7Z L;  2JA5 L;  5C4J L;  1TWA L;  3I4N L;  1SFO L;  1TWG L;  4BBS L;  3GTK L;  5M5X L;  3HOV L;  2PMZ P;  2R92 L;  3H3V M;  1I6H L;  4BBR L;  2JA6 L;  1K83 L;  4C3J L;  3GTQ L;  2JA7 L;  2NVY L;  3HOU L;  4A3K L;  1TWC L;  4A3D L;  3S15 L;  5FLM L;  4A3E L;  3S1N L;  3GTO L;  5C3E L;  1I50 L;  4QIW P;  3S1R L;  5C4X L;  2VUM L;  3GTG L;  1WCM L;  2Y0S P;  5M3F L;  3PO2 L;  3H0G L;  2NVQ L;  4C2M 1;  3RZD L;  4A3M L;  4A3G L;  4A3B L;  5IYC L;  4A3L L;  4BY1 L;  2E2H L;  3HOW L;  3HKZ P;  2YU9 L;  2B63 L;  1Y1W L;  3HOY L;  3HOZ L;  4A3F L;  3I4M L;  2NVX L;  3GTJ L;  1TWH L;  2E2J L;  2JA8 L;  3S14 L;  4Y52 L;  1I3Q L;  4C3I L;  1R9T L;  5C44 L;  3S16 L;  3GTP L;  5IYB L;  4BY7 L;  2E2I L;  5M5Y L;  4A3J L;  5IP9 L;  2R93 L;  4A3I L;  3K7A L; 
#chains in the Genus database with same CATH topology
 1PFW A;  3P2A A;  3HJW B;  1RYQ A;  5MGN A;  4C3H L;  5FJ8 L;  3H97 A;  3LPE B;  4TPU A;  3J7Z 1;  1IRN A;  2Z3R B;  2WB1 P;  5M3M L;  2ERJ A;  3PZA A;  1QCV A;  1NXE A;  4ME3 A;  2RFK B;  3S17 L;  2AUS B;  1SMW A;  3HOX L;  1PFY A;  3FKI L;  3S1Q L;  4JAE A;  2WAQ P;  2R7Z L;  2PVX A;  2CKA A;  2JI2 A;  3IU3 I;  4JAF A;  2JI1 A;  3GTK L;  5M5X L;  3HOV L;  1BE7 A;  2PMZ P;  3H3V M;  2JA6 L;  1K83 L;  1IU5 A;  4AR5 A;  1QYB A;  1SMU A;  4ZN1 B;  3S1N L;  2KN9 A;  3S1R L;  5C4X L;  5EIO C;  3GTG L;  1WCM L;  1R0G A;  2A68 D;  3HOW L;  3FDJ A;  2HR5 A;  5JVG 1;  1Y1W L;  1VZG A;  3PIP 1;  1SMM A;  5GAH c;  4XGH A;  2XJS A;  3PKJ A;  4RXN A;  1QQT A;  3LWQ B;  3MSU A;  1I3Q L;  1R0H A;  4AHW A;  1OWC A;  1R9T L;  4AR3 A;  5C44 L;  5MFP A;  3GTP L;  4K9F A;  3LWV B;  3S16 L;  4BY7 L;  3JR7 A;  4TVM A;  2PSM C;  1FHM A;  3LNL A;  3K7A L;  2XJT A;  1CAA A;  4AR6 A;  1RDG A;  1B13 A;  1PFV A;  1R0I A;  4GS7 D;  5IYD L;  4Y7N L;  4AYB P;  1YK5 A;  5M5W L;  1BQ8 A;  1PFU A;  2ERS A;  2PYA A;  5DM6 1;  3LWP B;  1Y1V L;  3KYY A;  4UY8 1;  2XJV A;  1SFO L;  1S2Z A;  1TWG L;  3LWO B;  4POG A;  1I6H L;  4BBR L;  2L0Z A;  2XJU A;  4C3J L;  3GTQ L;  2JA7 L;  2NVY L;  2QL0 A;  1B2J A;  3VPB E;  5FLM L;  5K2M E;  1RWD A;  4A3E L;  5RXN A;  1ODH A;  1E8J A;  4LHL A;  3HJY B;  3H99 A;  3B08 B;  2VUM L;  1YUZ A;  2Y0S P;  4B8C D;  1NXG A;  3PWF A;  2NVQ L;  3HAX C;  4C2M 1;  3RZD L;  3ZG6 A;  2V0F A;  4A3B L;  2XJQ A;  2BE5 D;  2LCQ A;  2DSX A;  1S24 A;  1YUX A;  2B63 L;  2YU9 L;  1BFY A;  5DM7 1;  4WFN 1;  2A6E D;  2K2D A;  2V0E A;  2NVX L;  4V19 6;  1Z92 B;  2JI3 A;  1C09 A;  3RZ6 A;  4YWL A;  1TWH L;  5GAG c;  3RYG A;  2JA8 L;  3S14 L;  4Y52 L;  5GAE c;  4U67 1;  4AHX A;  2M4V A;  5IYB L;  5H1S c;  2ZIX A;  4A3J L;  7RXN A;  2R93 L;  2Z3Q B;  4XXB B;  4BXX L;  1DVB A;  2EY4 E;  3KYU A;  4X6A L;  3PO3 L;  3CQZ L;  3MQK B;  5MLC 3;  3QQC E;  4A93 L;  1F4L A;  3S1M L;  1VCX A;  3M3Y L;  5IP7 L;  4A3C L;  1RYT A;  3M4O L;  3RZO L;  1OWB A;  3GTM L;  4YWM A;  2JA5 L;  4AI1 A;  3H9C A;  1T9Q A;  5MFZ A;  5IY0 A;  2A6H D;  4AI0 A;  5JVH 1;  2R92 L;  2MS3 A;  3KYX A;  5AI2 A;  4JAG A;  1VZI A;  3MPS A;  2NYD A;  4POF A;  3LWR B;  3HOU L;  4A3K L;  1B71 A;  4A3D L;  4AHZ A;  1T9P A;  3GTO L;  1I50 L;  3PIO 1;  2AYJ A;  5AI3 A;  8RXN A;  2J9U B;  4AI3 A;  4JAD A;  5M3F L;  3H0G L;  1S30 A;  1LKM A;  4A3G L;  5IYC L;  4A3L L;  2E2H L;  2KKD A;  2M6P A;  3HKZ P;  1WJV A;  3HOY L;  3PKI A;  1VZH A;  3I4M L;  5EIN C;  1LKO A;  1BQ9 A;  2M4Y A;  1YV1 A;  3WWL A;  1LTL A;  1IU6 A;  2GMG A;  1CAD A;  2RDV A;  2E2I L;  1YK4 A;  4AHY A;  5MF6 A;  2CR8 A;  3K35 A;  2PPT A;  2V3B B;  1TWF L;  1RB9 A;  2NVT L;  2APO B;  3GTL L;  4LHN A;  5AN9 H;  3S2H L;  3S2D L;  6RXN A;  2C6B A;  2HVY C;  3SS2 A;  4AI2 A;  2M6O A;  3KYW A;  5C4J L;  1TWA L;  1B2O A;  4G6B A;  3I4N L;  4BBS L;  2B5I D;  2VL6 A;  1H7V A;  3P8B A;  1JYB A;  1NNQ A;  3QVD A;  3KYV A;  2H12 A;  1T9O A;  1TWC L;  2XJP A;  2A69 D;  3J7Y 1;  3S15 L;  1P7P A;  3A44 A;  5C3E L;  4QIW P;  1DX8 A;  1RDV A;  3RZT A;  2C6A A;  4ZN3 B;  3PO2 L;  3H9B A;  4A3M L;  1FHH A;  1PZX A;  4AR4 A;  3B0A B;  1R0J A;  4BY1 L;  1BRF A;  1ZRP A;  1R0F A;  3HOZ L;  4A3F L;  1LKP A;  1IRO A;  3GTJ L;  2E2J L;  2CKC A;  2O5J D;  4C3I L;  1IW7 D;  2PVE A;  3WWN B;  3NFP I;  2AQC A;  3PL5 A;  4E6Y A;  5M5Y L;  5IP9 L;  2XJR A;  4A3I L;  5GAD c; 
#chains in the Genus database with same CATH homology
 4BXX L;  1TWF L;  2NVT L;  3PO3 L;  4X6A L;  3CQZ L;  4C3H L;  5FJ8 L;  3GTL L;  4Y7N L;  5IYD L;  3S2H L;  4AYB P;  3S2D L;  2WB1 P;  4A93 L;  5M3M L;  3S1M L;  3M3Y L;  5IP7 L;  4A3C L;  5M5W L;  3S17 L;  3M4O L;  3RZO L;  3HOX L;  3FKI L;  3GTM L;  3S1Q L;  2WAQ P;  1Y1V L;  2R7Z L;  2JA5 L;  5C4J L;  1TWA L;  3I4N L;  1SFO L;  1TWG L;  4BBS L;  3GTK L;  5M5X L;  3HOV L;  2PMZ P;  2R92 L;  3H3V M;  1I6H L;  4BBR L;  2JA6 L;  1K83 L;  4C3J L;  3GTQ L;  2JA7 L;  2NVY L;  3HOU L;  4A3K L;  1TWC L;  4A3D L;  3S15 L;  5FLM L;  4A3E L;  3S1N L;  3GTO L;  5C3E L;  1I50 L;  4QIW P;  3S1R L;  5C4X L;  2VUM L;  3GTG L;  1WCM L;  2Y0S P;  5M3F L;  3PO2 L;  3H0G L;  2NVQ L;  4C2M 1;  3RZD L;  4A3M L;  4A3G L;  4A3B L;  5IYC L;  4A3L L;  4BY1 L;  2E2H L;  3HOW L;  3HKZ P;  2YU9 L;  2B63 L;  1Y1W L;  3HOY L;  3HOZ L;  4A3F L;  3I4M L;  2NVX L;  3GTJ L;  1TWH L;  2E2J L;  2JA8 L;  3S14 L;  4Y52 L;  1I3Q L;  4C3I L;  1R9T L;  5C44 L;  3S16 L;  3GTP L;  5IYB L;  4BY7 L;  2E2I L;  5M5Y L;  4A3J L;  5IP9 L;  2R93 L;  4A3I L;  3K7A L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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