2NVQL

Rna polymerase ii elongation complex in 150 mm mg+2 with 2'dutp
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'
total genus 2
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2006-11-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2nvqL00
3HOZL 3S15L 3K7AL 5FLML 2E2JL 5M5YL 1TWCL 5FJ8L 3GTPL 5IP9L 3H0GL 1I3QL 2YU9L 4A3DL 3M3YL 3GTJL 3S16L 4BXXL 3GTML 1I6HL 5IP7L 3PO3L 3RZOL 5C4JL 3GTGL 3GTKL 3HOUL 3GTQL 1TWAL 4A3JL 3FKIL 4C3JL 1R9TL 3HOYL 5C44L 1TWGL 2VUML 3RZDL 2NVXL 3I4NL 2PMZP 4A93L 3S17L 3S14L 2JA6L 4Y7NL 1Y1VL 5IYBL 3CQZL 3HOXL 4X6AL 5IYCL 4C3IL 4A3BL 2NVYL 3S2HL 1K83L 4Y52L 4BBRL 3PO2L 2R7ZL 4A3KL 3H3VM 5M3FL 1SFOL 5M3ML 4A3LL 3S1QL 5C3EL 3HKZP 4A3CL 1I50L 2E2HL 2JA5L 2JA7L 2B63L 2JA8L 5IYDL 1Y1WL 3HOVL 3S2DL 2NVQL 3S1ML 5M5XL 2R92L 4AYBP 2NVTL 2R93L 4C2M1 1TWFL 4QIWP 2WB1P 2E2IL 3S1RL 3GTOL 3HOWL 4A3GL 1TWHL 5C4XL 4A3FL 2Y0SP 3I4ML 4C3HL 3S1NL 4BY7L 5M5WL 4A3IL 4A3EL 2WAQP 4BY1L 3GTLL 4BBSL 1WCML 3M4OL 4A3ML
chains in the Genus database with same CATH superfamily
1IW7D 3K7AL 5FLML 2E2JL 3GTPL 5AN9H 3MQKB 3PZAA 2CR8A 4AI3A 1BRFA 3PWFA 1BQ8A 2XJVA 2EY4E 2JI3A 4TPUA 1NXGA 1RDGA 1SMWA 5IP7L 3KYVA 1T9OA 2M6OA 2PYAA 3HOUL 3WWLA 2K2DA 4ZN1B 5MF6A 4AR4A 2PVEA 4ZN3B 2HR5A 1DVBA 3JR7A 4AR5A 3B0AB 1SMUA 1S30A 2JI1A 2XJQA 4A93L 3S17L 3S14L 1Y1VL 2C6BA 1RDVA 2ZIXA 2M6PA 5EINC 5H1Sc 3H99A 4A3BL 1K83L 5JVH1 4E6YA 1B2OA 1JYBA 3RYGA 4GS7D 5M3ML 3S1QL 2XJTA 2E2HL 2JA7L 1QQTA 1IROA 5JVG1 2JA8L 1NXEA 3K35A 3S2DL 1ZRPA 2NVQL 3MPSA 3S1ML 2R92L 4AYBP 2NVTL 1TWFL 2E2IL 2A6ED 2VL6A 3HAXC 2A68D 2Y0SP 2AYJA 4K9FA 1IRNA 5M5WL 4A3IL 4A3EL 2WAQP 3NFPI 3GTLL 3IU3I 3M4OL 4JAFA 1FHHA 2RFKB 1NNQA 5FJ8L 5IP9L 1RB9A 5DM71 3S16L 2M4VA 4XGHA 4YWMA 5GADc 4G6BA 4POGA 3GTGL 3LWVB 2PVXA 3HJWB 3GTQL 2V0FA 1TWAL 2AUSB 3FKIL 3HOYL 5C44L 2Z3QB 1SMMA 3LNLA 3RZDL 2RDVA 2XJRA 3A44A 4AHXA 1OWBA 1VCXA 1PFWA 3CQZL 4X6AL 4B8CD 4YWLA 4C3IL 1R0JA 3S2HL 4Y52L 1YUZA 3WWNB 5EIOC 1DX8A 1Z92B 3J7Y1 4A3LL 1BQ9A 5C3EL 1LTLA 1P7PA 3MSUA 1ODHA 5MFPA 2LCQA 3PKIA 4AI2A 5MFZA 3ZG6A 5M5XL 3P2AA 3PKJA 3GTOL 3LPEB 2AQCA 2BE5D 3RZTA 1IU5A 3I4ML 4C3HL 3S1NL 4BY7L 3VPBE 1T9QA 2ERJA 4POFA 2APOB 1LKMA 3P8BA 2PSMC 4A3ML 3HOZL 4AHYA 4UY81 1OWCA 1S24A 1RYQA 2V0EA 1VZIA 2B5ID 4A3DL 2KN9A 2Z3RB 2V3BB 3M3YL 3GTJL 1PFYA 4AR6A 3KYUA 1YUXA 3PIO1 2H12A 3QVDA 1I6HL 3PO3L 1QCVA 3PL5A 3B08B 5AI2A 4A3JL 4C3JL 1R9TL 3PIP1 2JI2A 3LWOB 4LHLA 2A69D 3I4NL 5IYBL 1YV1A 4LHNA 1CAAA 3HOXL 4AI1A 5IYCL 2NVYL 4BBRL 3PO2L 3QQCE 1YK5A 4JAEA 2A6HD 3KYXA 1B13A 1R0GA 4A3CL 2JA5L 1PFVA 2MS3A 1R0FA 5IYDL 1Y1WL 3HOVL 2R93L 4QIWP 2WB1P 3S1RL 2NYDA 2CKAA 3HOWL 3SS2A 5C4XL 1C09A 4A3FL 1F4LA 3RZ6A 8RXNA 1R0HA 4ME3A 2DSXA 3J7Z1 1QYBA 4TVMA 4BY1L 2J9UB 1WCML 4JAGA 1RWDA 1LKOA 2C6AA 2GMGA 4V196 3S15L 1T9PA 6RXNA 4XXBB 5M5YL 1TWCL 1VZGA 2PPTA 3H0GL 3H97A 5RXNA 1I3QL 2YU9L 1FHMA 3HJYB 1VZHA 5MGNA 1B2JA 1CADA 5MLC3 2XJPA 3H9BA 4WFN1 4BXXL 3GTML 2M4YA 3FDJA 5GAGc 3RZOL 5C4JL 5DM61 1R0IA 3GTKL 2ERSA 1TWGL 2VUML 4AHWA 2NVXL 2PMZP 5GAEc 2JA6L 3H9CA 4AR3A 4U671 4Y7NL 1PFUA 5AI3A 3LWRB 2O5JD 2R7ZL 5GAHc 4A3KL 3H3VM 5M3FL 1SFOL 3LWPB 2L0ZA 1S2ZA 3HKZP 1I50L 4AHZA 2HVYC 1YK4A 5IY0A 1H7VA 2B63L 1BFYA 1BE7A 2QL0A 1IU6A 2KKDA 2CKCA 4C2M1 1B71A 2XJSA 4RXNA 1RYTA 2XJUA 1E8JA 4A3GL 3LWQB 1TWHL 3KYWA 1LKPA 4JADA 4AI0A 1WJVA 3KYYA 5K2ME 4BBSL 1PZXA 7RXNA
chains in the Genus database with same CATH topology
3HOZL 3S15L 3K7AL 5FLML 2E2JL 5M5YL 1TWCL 5FJ8L 3GTPL 5IP9L 3H0GL 1I3QL 2YU9L 4A3DL 3M3YL 3GTJL 3S16L 4BXXL 3GTML 1I6HL 5IP7L 3PO3L 3RZOL 5C4JL 3GTGL 3GTKL 3HOUL 3GTQL 1TWAL 4A3JL 3FKIL 4C3JL 1R9TL 3HOYL 5C44L 1TWGL 2VUML 3RZDL 2NVXL 3I4NL 2PMZP 4A93L 3S17L 3S14L 2JA6L 4Y7NL 1Y1VL 5IYBL 3CQZL 3HOXL 4X6AL 5IYCL 4C3IL 4A3BL 2NVYL 3S2HL 1K83L 4Y52L 4BBRL 3PO2L 2R7ZL 4A3KL 3H3VM 5M3FL 1SFOL 5M3ML 4A3LL 3S1QL 5C3EL 3HKZP 4A3CL 1I50L 2E2HL 2JA5L 2JA7L 2B63L 2JA8L 5IYDL 1Y1WL 3HOVL 3S2DL 2NVQL 3S1ML 5M5XL 2R92L 4AYBP 2NVTL 2R93L 4C2M1 1TWFL 4QIWP 2WB1P 2E2IL 3S1RL 3GTOL 3HOWL 4A3GL 1TWHL 5C4XL 4A3FL 2Y0SP 3I4ML 4C3HL 3S1NL 4BY7L 5M5WL 4A3IL 4A3EL 2WAQP 4BY1L 3GTLL 4BBSL 1WCML 3M4OL 4A3ML
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HOZ L;  3S15 L;  3K7A L;  5FLM L;  2E2J L;  5M5Y L;  1TWC L;  5FJ8 L;  3GTP L;  5IP9 L;  3H0G L;  1I3Q L;  2YU9 L;  4A3D L;  3M3Y L;  3GTJ L;  3S16 L;  4BXX L;  3GTM L;  1I6H L;  5IP7 L;  3PO3 L;  3RZO L;  5C4J L;  3GTG L;  3GTK L;  3HOU L;  3GTQ L;  1TWA L;  4A3J L;  3FKI L;  4C3J L;  1R9T L;  3HOY L;  5C44 L;  1TWG L;  2VUM L;  3RZD L;  2NVX L;  3I4N L;  2PMZ P;  4A93 L;  3S17 L;  3S14 L;  2JA6 L;  4Y7N L;  1Y1V L;  5IYB L;  3CQZ L;  3HOX L;  4X6A L;  5IYC L;  4C3I L;  4A3B L;  2NVY L;  3S2H L;  1K83 L;  4Y52 L;  4BBR L;  3PO2 L;  2R7Z L;  4A3K L;  3H3V M;  5M3F L;  1SFO L;  5M3M L;  4A3L L;  3S1Q L;  5C3E L;  3HKZ P;  4A3C L;  1I50 L;  2E2H L;  2JA5 L;  2JA7 L;  2B63 L;  2JA8 L;  5IYD L;  1Y1W L;  3HOV L;  3S2D L;  2NVQ L;  3S1M L;  5M5X L;  2R92 L;  4AYB P;  2NVT L;  2R93 L;  4C2M 1;  1TWF L;  4QIW P;  2WB1 P;  2E2I L;  3S1R L;  3GTO L;  3HOW L;  4A3G L;  1TWH L;  5C4X L;  4A3F L;  2Y0S P;  3I4M L;  4C3H L;  3S1N L;  4BY7 L;  5M5W L;  4A3I L;  4A3E L;  2WAQ P;  4BY1 L;  3GTL L;  4BBS L;  1WCM L;  3M4O L;  4A3M L; 
#chains in the Genus database with same CATH topology
 1IW7 D;  3K7A L;  5FLM L;  2E2J L;  3GTP L;  5AN9 H;  3MQK B;  3PZA A;  2CR8 A;  4AI3 A;  1BRF A;  3PWF A;  1BQ8 A;  2XJV A;  2EY4 E;  2JI3 A;  4TPU A;  1NXG A;  1RDG A;  1SMW A;  5IP7 L;  3KYV A;  1T9O A;  2M6O A;  2PYA A;  3HOU L;  3WWL A;  2K2D A;  4ZN1 B;  5MF6 A;  4AR4 A;  2PVE A;  4ZN3 B;  2HR5 A;  1DVB A;  3JR7 A;  4AR5 A;  3B0A B;  1SMU A;  1S30 A;  2JI1 A;  2XJQ A;  4A93 L;  3S17 L;  3S14 L;  1Y1V L;  2C6B A;  1RDV A;  2ZIX A;  2M6P A;  5EIN C;  5H1S c;  3H99 A;  4A3B L;  1K83 L;  5JVH 1;  4E6Y A;  1B2O A;  1JYB A;  3RYG A;  4GS7 D;  5M3M L;  3S1Q L;  2XJT A;  2E2H L;  2JA7 L;  1QQT A;  1IRO A;  5JVG 1;  2JA8 L;  1NXE A;  3K35 A;  3S2D L;  1ZRP A;  2NVQ L;  3MPS A;  3S1M L;  2R92 L;  4AYB P;  2NVT L;  1TWF L;  2E2I L;  2A6E D;  2VL6 A;  3HAX C;  2A68 D;  2Y0S P;  2AYJ A;  4K9F A;  1IRN A;  5M5W L;  4A3I L;  4A3E L;  2WAQ P;  3NFP I;  3GTL L;  3IU3 I;  3M4O L;  4JAF A;  1FHH A;  2RFK B;  1NNQ A;  5FJ8 L;  5IP9 L;  1RB9 A;  5DM7 1;  3S16 L;  2M4V A;  4XGH A;  4YWM A;  5GAD c;  4G6B A;  4POG A;  3GTG L;  3LWV B;  2PVX A;  3HJW B;  3GTQ L;  2V0F A;  1TWA L;  2AUS B;  3FKI L;  3HOY L;  5C44 L;  2Z3Q B;  1SMM A;  3LNL A;  3RZD L;  2RDV A;  2XJR A;  3A44 A;  4AHX A;  1OWB A;  1VCX A;  1PFW A;  3CQZ L;  4X6A L;  4B8C D;  4YWL A;  4C3I L;  1R0J A;  3S2H L;  4Y52 L;  1YUZ A;  3WWN B;  5EIO C;  1DX8 A;  1Z92 B;  3J7Y 1;  4A3L L;  1BQ9 A;  5C3E L;  1LTL A;  1P7P A;  3MSU A;  1ODH A;  5MFP A;  2LCQ A;  3PKI A;  4AI2 A;  5MFZ A;  3ZG6 A;  5M5X L;  3P2A A;  3PKJ A;  3GTO L;  3LPE B;  2AQC A;  2BE5 D;  3RZT A;  1IU5 A;  3I4M L;  4C3H L;  3S1N L;  4BY7 L;  3VPB E;  1T9Q A;  2ERJ A;  4POF A;  2APO B;  1LKM A;  3P8B A;  2PSM C;  4A3M L;  3HOZ L;  4AHY A;  4UY8 1;  1OWC A;  1S24 A;  1RYQ A;  2V0E A;  1VZI A;  2B5I D;  4A3D L;  2KN9 A;  2Z3R B;  2V3B B;  3M3Y L;  3GTJ L;  1PFY A;  4AR6 A;  3KYU A;  1YUX A;  3PIO 1;  2H12 A;  3QVD A;  1I6H L;  3PO3 L;  1QCV A;  3PL5 A;  3B08 B;  5AI2 A;  4A3J L;  4C3J L;  1R9T L;  3PIP 1;  2JI2 A;  3LWO B;  4LHL A;  2A69 D;  3I4N L;  5IYB L;  1YV1 A;  4LHN A;  1CAA A;  3HOX L;  4AI1 A;  5IYC L;  2NVY L;  4BBR L;  3PO2 L;  3QQC E;  1YK5 A;  4JAE A;  2A6H D;  3KYX A;  1B13 A;  1R0G A;  4A3C L;  2JA5 L;  1PFV A;  2MS3 A;  1R0F A;  5IYD L;  1Y1W L;  3HOV L;  2R93 L;  4QIW P;  2WB1 P;  3S1R L;  2NYD A;  2CKA A;  3HOW L;  3SS2 A;  5C4X L;  1C09 A;  4A3F L;  1F4L A;  3RZ6 A;  8RXN A;  1R0H A;  4ME3 A;  2DSX A;  3J7Z 1;  1QYB A;  4TVM A;  4BY1 L;  2J9U B;  1WCM L;  4JAG A;  1RWD A;  1LKO A;  2C6A A;  2GMG A;  4V19 6;  3S15 L;  1T9P A;  6RXN A;  4XXB B;  5M5Y L;  1TWC L;  1VZG A;  2PPT A;  3H0G L;  3H97 A;  5RXN A;  1I3Q L;  2YU9 L;  1FHM A;  3HJY B;  1VZH A;  5MGN A;  1B2J A;  1CAD A;  5MLC 3;  2XJP A;  3H9B A;  4WFN 1;  4BXX L;  3GTM L;  2M4Y A;  3FDJ A;  5GAG c;  3RZO L;  5C4J L;  5DM6 1;  1R0I A;  3GTK L;  2ERS A;  1TWG L;  2VUM L;  4AHW A;  2NVX L;  2PMZ P;  5GAE c;  2JA6 L;  3H9C A;  4AR3 A;  4U67 1;  4Y7N L;  1PFU A;  5AI3 A;  3LWR B;  2O5J D;  2R7Z L;  5GAH c;  4A3K L;  3H3V M;  5M3F L;  1SFO L;  3LWP B;  2L0Z A;  1S2Z A;  3HKZ P;  1I50 L;  4AHZ A;  2HVY C;  1YK4 A;  5IY0 A;  1H7V A;  2B63 L;  1BFY A;  1BE7 A;  2QL0 A;  1IU6 A;  2KKD A;  2CKC A;  4C2M 1;  1B71 A;  2XJS A;  4RXN A;  1RYT A;  2XJU A;  1E8J A;  4A3G L;  3LWQ B;  1TWH L;  3KYW A;  1LKP A;  4JAD A;  4AI0 A;  1WJV A;  3KYY A;  5K2M E;  4BBS L;  1PZX A;  7RXN A; 
#chains in the Genus database with same CATH homology
 3HOZ L;  3S15 L;  3K7A L;  5FLM L;  2E2J L;  5M5Y L;  1TWC L;  5FJ8 L;  3GTP L;  5IP9 L;  3H0G L;  1I3Q L;  2YU9 L;  4A3D L;  3M3Y L;  3GTJ L;  3S16 L;  4BXX L;  3GTM L;  1I6H L;  5IP7 L;  3PO3 L;  3RZO L;  5C4J L;  3GTG L;  3GTK L;  3HOU L;  3GTQ L;  1TWA L;  4A3J L;  3FKI L;  4C3J L;  1R9T L;  3HOY L;  5C44 L;  1TWG L;  2VUM L;  3RZD L;  2NVX L;  3I4N L;  2PMZ P;  4A93 L;  3S17 L;  3S14 L;  2JA6 L;  4Y7N L;  1Y1V L;  5IYB L;  3CQZ L;  3HOX L;  4X6A L;  5IYC L;  4C3I L;  4A3B L;  2NVY L;  3S2H L;  1K83 L;  4Y52 L;  4BBR L;  3PO2 L;  2R7Z L;  4A3K L;  3H3V M;  5M3F L;  1SFO L;  5M3M L;  4A3L L;  3S1Q L;  5C3E L;  3HKZ P;  4A3C L;  1I50 L;  2E2H L;  2JA5 L;  2JA7 L;  2B63 L;  2JA8 L;  5IYD L;  1Y1W L;  3HOV L;  3S2D L;  2NVQ L;  3S1M L;  5M5X L;  2R92 L;  4AYB P;  2NVT L;  2R93 L;  4C2M 1;  1TWF L;  4QIW P;  2WB1 P;  2E2I L;  3S1R L;  3GTO L;  3HOW L;  4A3G L;  1TWH L;  5C4X L;  4A3F L;  2Y0S P;  3I4M L;  4C3H L;  3S1N L;  4BY7 L;  5M5W L;  4A3I L;  4A3E L;  2WAQ P;  4BY1 L;  3GTL L;  4BBS L;  1WCM L;  3M4O L;  4A3M L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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