2NVQL

Rna polymerase ii elongation complex in 150 mm mg+2 with 2'dutp
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'
publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
total genus 2
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2006-11-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2nvqL00
4A3DL 1TWAL 3HOWL 5IYDL 5IYCL 5C44L 2YU9L 3S16L 4BY1L 2WB1P 4A3FL 2Y0SP 4Y7NL 4AYBP 4C3IL 4QIWP 4C3JL 3GTQL 3HOUL 1TWCL 2E2HL 3CQZL 3GTOL 5IP7L 2E2JL 4BBRL 2B63L 4C3HL 3GTLL 4BBSL 5FJ8L 3GTPL 4A3GL 5C4XL 3RZDL 4A3CL 3RZOL 1I6HL 3S1NL 3I4NL 3HKZP 2R93L 3FKIL 5M5YL 4A93L 2JA8L 1WCML 1TWGL 1R9TL 1Y1VL 3GTML 4BY7L 3M3YL 2NVYL 3H0GL 4A3BL 5M3FL 2JA5L 3S1QL 3PO3L 4BXXL 1Y1WL 4X6AL 3HOVL 4C2M1 3HOYL 4A3JL 4A3EL 3S2DL 2VUML 1SFOL 2JA6L 1K83L 1TWHL 3GTJL 2WAQP 3I4ML 3S2HL 2NVXL 5FLML 2JA7L 5IYBL 2NVTL 5IP9L 3HOZL 5M5XL 3S15L 5C3EL 3H3VM 2E2IL 1I50L 3S17L 4Y52L 4A3KL 1I3QL 3K7AL 4A3ML 5M5WL 2R7ZL 1TWFL 4A3LL 2PMZP 3S1RL 5M3ML 4A3IL 3GTKL 3M4OL 3PO2L 3HOXL 3GTGL 5C4JL 3S14L 2NVQL 2R92L 3S1ML
chains in the Genus database with same CATH superfamily
1TWAL 3HOWL 1Z92B 1R0FA 2PYAA 2YU9L 5IY0A 2CKCA 1CADA 3KYYA 4BY1L 5JVH1 1IU5A 2Y0SP 1IRNA 1OWCA 4QIWP 4G6BA 4C3JL 4AHZA 4B8CD 3IU3I 5EIOC 3HAXC 3PKIA 5IP7L 3P2AA 1PFVA 3PKJA 2E2JL 5GADc 5K2ME 1VZIA 3GTPL 5C4XL 4AHYA 2A6HD 3RZOL 1I6HL 5GAGc 1RYQA 4YWLA 1R0GA 3FKIL 4TPUA 5M5YL 3KYXA 1WCML 1QYBA 2O5JD 5MFZA 4JADA 4BY7L 1PFYA 5MFPA 3M3YL 5AN9H 2XJUA 1T9QA 3PO3L 3PL5A 4BXXL 3HOYL 4A3JL 3B08B 2Z3QB 2Z3RB 1SFOL 1BRFA 3H97A 2CR8A 4AI1A 2WAQP 3WWLA 3S2HL 5FLML 2JA7L 2K2DA 5MGNA 3H99A 2PVEA 1I50L 1YK5A 3RYGA 4Y52L 2C6AA 1JYBA 4U671 4A3ML 2M6PA 5GAEc 2HVYC 3ZG6A 5JVG1 1TWFL 4A3LL 3FDJA 1SMUA 4LHLA 3HJWB 3GTGL 2JI3A 1VZHA 3S1ML 1OWBA 1B71A 4ME3A 5IYCL 1H7VA 5C44L 1BE7A 1SMWA 4GS7D 2PVXA 2WB1P 4Y7NL 1LTLA 4C3IL 1TWCL 2E2HL 2PPTA 3RZTA 2BE5D 3H9CA 2PSMC 4AHXA 4C3HL 4BBSL 4A3GL 2V3BB 3RZDL 4YWMA 1R0HA 2EY4E 4POFA 4AI2A 3S1NL 4AI0A 2R93L 8RXNA 4A93L 2KN9A 1TWGL 1QQTA 5AI2A 4AR3A 1BFYA 3VPBE 5GAHc 4A3BL 4X6AL 3HOVL 4C2M1 2V0EA 2AUSB 4JAFA 2KKDA 3S2DL 2VUML 3B0AB 3J7Z1 1BQ9A 1TWHL 1LKMA 2XJSA 3I4ML 4POGA 1IROA 1IW7D 2XJVA 1WJVA 5IP9L 5M5XL 3S15L 3RZ6A 1E8JA 2JI2A 5DM61 3SS2A 1T9OA 1DX8A 4WFN1 3S17L 1CAAA 2XJPA 1I3QL 2XJRA 3QVDA 3WWNB 1C09A 5M3ML 4A3IL 1DVBA 1YUZA 2XJTA 5MLC3 3PIP1 5IYDL 1PFUA 2C6BA 1S30A 5RXNA 7RXNA 4AR6A 3LWOB 4A3FL 1LKOA 3HOUL 2B5ID 3CQZL 3P8BA 1VCXA 4BBRL 2M4YA 1S24A 1VZGA 3LPEB 1B2JA 3GTLL 3LWPB 5FJ8L 3H9BA 1R0JA 1PFWA 4A3CL 1FHMA 4E6YA 1B2OA 3JR7A 3I4NL 1YV1A 1SMMA 2JA8L 1YUXA 2V0FA 1NXEA 1R9TL 1Y1VL 1PZXA 1T9PA 3MSUA 2DSXA 1RDVA 3H0GL 5M3FL 3S1QL 1Y1WL 2VL6A 1ODHA 3PIO1 2RDVA 2JA6L 2CKAA 1K83L 2M4VA 3GTJL 3PWFA 3MPSA 1YK4A 2ERSA 4AHWA 1R0IA 2NVXL 2NVTL 3HOZL 3K35A 1QCVA 3H3VM 2E2IL 5MF6A 1ZRPA 4A3KL 2XJQA 4AR4A 4TVMA 5M5WL 2A69D 2R7ZL 4JAEA 1LKPA 2LCQA 3M4OL 3KYWA 3PO2L 3S14L 5EINC 1FHHA 4A3DL 3PZAA 3NFPI 3S16L 3LWRB 5H1Sc 2J9UB 1S2ZA 4AYBP 4ZN3B 3GTQL 4LHNA 2MS3A 1RYTA 1F4LA 4ZN1B 2QL0A 3GTOL 4UY81 3KYVA 2A68D 4V196 6RXNA 2B63L 1BQ8A 4XGHA 2NYDA 3J7Y1 2GMGA 3KYUA 3HKZP 3LWQB 2ERJA 3GTML 5DM71 3A44A 4K9FA 2NVYL 3LWVB 2JA5L 1RB9A 5AI3A 2RFKB 3HJYB 4JAGA 4A3EL 4XXBB 1RDGA 2M6OA 2AYJA 2H12A 2HR5A 4AR5A 5IYBL 3QQCE 3LNLA 1NXGA 1NNQA 5C3EL 2A6ED 2L0ZA 4RXNA 3MQKB 2ZIXA 3K7AL 2JI1A 1RWDA 2APOB 3S1RL 2PMZP 1IU6A 1P7PA 4AI3A 3GTKL 3HOXL 5C4JL 1B13A 2NVQL 2R92L 2AQCA
chains in the Genus database with same CATH topology
4A3DL 1TWAL 3HOWL 5IYDL 5IYCL 5C44L 2YU9L 3S16L 4BY1L 2WB1P 4A3FL 2Y0SP 4Y7NL 4AYBP 4C3IL 4QIWP 4C3JL 3GTQL 3HOUL 1TWCL 2E2HL 3CQZL 3GTOL 5IP7L 2E2JL 4BBRL 2B63L 4C3HL 3GTLL 4BBSL 5FJ8L 3GTPL 4A3GL 5C4XL 3RZDL 4A3CL 3RZOL 1I6HL 3S1NL 3I4NL 3HKZP 2R93L 3FKIL 5M5YL 4A93L 2JA8L 1WCML 1TWGL 1R9TL 1Y1VL 3GTML 4BY7L 3M3YL 2NVYL 3H0GL 4A3BL 5M3FL 2JA5L 3S1QL 3PO3L 4BXXL 1Y1WL 4X6AL 3HOVL 4C2M1 3HOYL 4A3JL 4A3EL 3S2DL 2VUML 1SFOL 2JA6L 1K83L 1TWHL 3GTJL 2WAQP 3I4ML 3S2HL 2NVXL 5FLML 2JA7L 5IYBL 2NVTL 5IP9L 3HOZL 5M5XL 3S15L 5C3EL 3H3VM 2E2IL 1I50L 3S17L 4Y52L 4A3KL 1I3QL 3K7AL 4A3ML 5M5WL 2R7ZL 1TWFL 4A3LL 2PMZP 3S1RL 5M3ML 4A3IL 3GTKL 3M4OL 3PO2L 3HOXL 3GTGL 5C4JL 3S14L 2NVQL 2R92L 3S1ML
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3D L;  1TWA L;  3HOW L;  5IYD L;  5IYC L;  5C44 L;  2YU9 L;  3S16 L;  4BY1 L;  2WB1 P;  4A3F L;  2Y0S P;  4Y7N L;  4AYB P;  4C3I L;  4QIW P;  4C3J L;  3GTQ L;  3HOU L;  1TWC L;  2E2H L;  3CQZ L;  3GTO L;  5IP7 L;  2E2J L;  4BBR L;  2B63 L;  4C3H L;  3GTL L;  4BBS L;  5FJ8 L;  3GTP L;  4A3G L;  5C4X L;  3RZD L;  4A3C L;  3RZO L;  1I6H L;  3S1N L;  3I4N L;  3HKZ P;  2R93 L;  3FKI L;  5M5Y L;  4A93 L;  2JA8 L;  1WCM L;  1TWG L;  1R9T L;  1Y1V L;  3GTM L;  4BY7 L;  3M3Y L;  2NVY L;  3H0G L;  4A3B L;  5M3F L;  2JA5 L;  3S1Q L;  3PO3 L;  4BXX L;  1Y1W L;  4X6A L;  3HOV L;  4C2M 1;  3HOY L;  4A3J L;  4A3E L;  3S2D L;  2VUM L;  1SFO L;  2JA6 L;  1K83 L;  1TWH L;  3GTJ L;  2WAQ P;  3I4M L;  3S2H L;  2NVX L;  5FLM L;  2JA7 L;  5IYB L;  2NVT L;  5IP9 L;  3HOZ L;  5M5X L;  3S15 L;  5C3E L;  3H3V M;  2E2I L;  1I50 L;  3S17 L;  4Y52 L;  4A3K L;  1I3Q L;  3K7A L;  4A3M L;  5M5W L;  2R7Z L;  1TWF L;  4A3L L;  2PMZ P;  3S1R L;  5M3M L;  4A3I L;  3GTK L;  3M4O L;  3PO2 L;  3HOX L;  3GTG L;  5C4J L;  3S14 L;  2NVQ L;  2R92 L;  3S1M L; 
#chains in the Genus database with same CATH topology
 1TWA L;  3HOW L;  1Z92 B;  1R0F A;  2PYA A;  2YU9 L;  5IY0 A;  2CKC A;  1CAD A;  3KYY A;  4BY1 L;  5JVH 1;  1IU5 A;  2Y0S P;  1IRN A;  1OWC A;  4QIW P;  4G6B A;  4C3J L;  4AHZ A;  4B8C D;  3IU3 I;  5EIO C;  3HAX C;  3PKI A;  5IP7 L;  3P2A A;  1PFV A;  3PKJ A;  2E2J L;  5GAD c;  5K2M E;  1VZI A;  3GTP L;  5C4X L;  4AHY A;  2A6H D;  3RZO L;  1I6H L;  5GAG c;  1RYQ A;  4YWL A;  1R0G A;  3FKI L;  4TPU A;  5M5Y L;  3KYX A;  1WCM L;  1QYB A;  2O5J D;  5MFZ A;  4JAD A;  4BY7 L;  1PFY A;  5MFP A;  3M3Y L;  5AN9 H;  2XJU A;  1T9Q A;  3PO3 L;  3PL5 A;  4BXX L;  3HOY L;  4A3J L;  3B08 B;  2Z3Q B;  2Z3R B;  1SFO L;  1BRF A;  3H97 A;  2CR8 A;  4AI1 A;  2WAQ P;  3WWL A;  3S2H L;  5FLM L;  2JA7 L;  2K2D A;  5MGN A;  3H99 A;  2PVE A;  1I50 L;  1YK5 A;  3RYG A;  4Y52 L;  2C6A A;  1JYB A;  4U67 1;  4A3M L;  2M6P A;  5GAE c;  2HVY C;  3ZG6 A;  5JVG 1;  1TWF L;  4A3L L;  3FDJ A;  1SMU A;  4LHL A;  3HJW B;  3GTG L;  2JI3 A;  1VZH A;  3S1M L;  1OWB A;  1B71 A;  4ME3 A;  5IYC L;  1H7V A;  5C44 L;  1BE7 A;  1SMW A;  4GS7 D;  2PVX A;  2WB1 P;  4Y7N L;  1LTL A;  4C3I L;  1TWC L;  2E2H L;  2PPT A;  3RZT A;  2BE5 D;  3H9C A;  2PSM C;  4AHX A;  4C3H L;  4BBS L;  4A3G L;  2V3B B;  3RZD L;  4YWM A;  1R0H A;  2EY4 E;  4POF A;  4AI2 A;  3S1N L;  4AI0 A;  2R93 L;  8RXN A;  4A93 L;  2KN9 A;  1TWG L;  1QQT A;  5AI2 A;  4AR3 A;  1BFY A;  3VPB E;  5GAH c;  4A3B L;  4X6A L;  3HOV L;  4C2M 1;  2V0E A;  2AUS B;  4JAF A;  2KKD A;  3S2D L;  2VUM L;  3B0A B;  3J7Z 1;  1BQ9 A;  1TWH L;  1LKM A;  2XJS A;  3I4M L;  4POG A;  1IRO A;  1IW7 D;  2XJV A;  1WJV A;  5IP9 L;  5M5X L;  3S15 L;  3RZ6 A;  1E8J A;  2JI2 A;  5DM6 1;  3SS2 A;  1T9O A;  1DX8 A;  4WFN 1;  3S17 L;  1CAA A;  2XJP A;  1I3Q L;  2XJR A;  3QVD A;  3WWN B;  1C09 A;  5M3M L;  4A3I L;  1DVB A;  1YUZ A;  2XJT A;  5MLC 3;  3PIP 1;  5IYD L;  1PFU A;  2C6B A;  1S30 A;  5RXN A;  7RXN A;  4AR6 A;  3LWO B;  4A3F L;  1LKO A;  3HOU L;  2B5I D;  3CQZ L;  3P8B A;  1VCX A;  4BBR L;  2M4Y A;  1S24 A;  1VZG A;  3LPE B;  1B2J A;  3GTL L;  3LWP B;  5FJ8 L;  3H9B A;  1R0J A;  1PFW A;  4A3C L;  1FHM A;  4E6Y A;  1B2O A;  3JR7 A;  3I4N L;  1YV1 A;  1SMM A;  2JA8 L;  1YUX A;  2V0F A;  1NXE A;  1R9T L;  1Y1V L;  1PZX A;  1T9P A;  3MSU A;  2DSX A;  1RDV A;  3H0G L;  5M3F L;  3S1Q L;  1Y1W L;  2VL6 A;  1ODH A;  3PIO 1;  2RDV A;  2JA6 L;  2CKA A;  1K83 L;  2M4V A;  3GTJ L;  3PWF A;  3MPS A;  1YK4 A;  2ERS A;  4AHW A;  1R0I A;  2NVX L;  2NVT L;  3HOZ L;  3K35 A;  1QCV A;  3H3V M;  2E2I L;  5MF6 A;  1ZRP A;  4A3K L;  2XJQ A;  4AR4 A;  4TVM A;  5M5W L;  2A69 D;  2R7Z L;  4JAE A;  1LKP A;  2LCQ A;  3M4O L;  3KYW A;  3PO2 L;  3S14 L;  5EIN C;  1FHH A;  4A3D L;  3PZA A;  3NFP I;  3S16 L;  3LWR B;  5H1S c;  2J9U B;  1S2Z A;  4AYB P;  4ZN3 B;  3GTQ L;  4LHN A;  2MS3 A;  1RYT A;  1F4L A;  4ZN1 B;  2QL0 A;  3GTO L;  4UY8 1;  3KYV A;  2A68 D;  4V19 6;  6RXN A;  2B63 L;  1BQ8 A;  4XGH A;  2NYD A;  3J7Y 1;  2GMG A;  3KYU A;  3HKZ P;  3LWQ B;  2ERJ A;  3GTM L;  5DM7 1;  3A44 A;  4K9F A;  2NVY L;  3LWV B;  2JA5 L;  1RB9 A;  5AI3 A;  2RFK B;  3HJY B;  4JAG A;  4A3E L;  4XXB B;  1RDG A;  2M6O A;  2AYJ A;  2H12 A;  2HR5 A;  4AR5 A;  5IYB L;  3QQC E;  3LNL A;  1NXG A;  1NNQ A;  5C3E L;  2A6E D;  2L0Z A;  4RXN A;  3MQK B;  2ZIX A;  3K7A L;  2JI1 A;  1RWD A;  2APO B;  3S1R L;  2PMZ P;  1IU6 A;  1P7P A;  4AI3 A;  3GTK L;  3HOX L;  5C4J L;  1B13 A;  2NVQ L;  2R92 L;  2AQC A; 
#chains in the Genus database with same CATH homology
 4A3D L;  1TWA L;  3HOW L;  5IYD L;  5IYC L;  5C44 L;  2YU9 L;  3S16 L;  4BY1 L;  2WB1 P;  4A3F L;  2Y0S P;  4Y7N L;  4AYB P;  4C3I L;  4QIW P;  4C3J L;  3GTQ L;  3HOU L;  1TWC L;  2E2H L;  3CQZ L;  3GTO L;  5IP7 L;  2E2J L;  4BBR L;  2B63 L;  4C3H L;  3GTL L;  4BBS L;  5FJ8 L;  3GTP L;  4A3G L;  5C4X L;  3RZD L;  4A3C L;  3RZO L;  1I6H L;  3S1N L;  3I4N L;  3HKZ P;  2R93 L;  3FKI L;  5M5Y L;  4A93 L;  2JA8 L;  1WCM L;  1TWG L;  1R9T L;  1Y1V L;  3GTM L;  4BY7 L;  3M3Y L;  2NVY L;  3H0G L;  4A3B L;  5M3F L;  2JA5 L;  3S1Q L;  3PO3 L;  4BXX L;  1Y1W L;  4X6A L;  3HOV L;  4C2M 1;  3HOY L;  4A3J L;  4A3E L;  3S2D L;  2VUM L;  1SFO L;  2JA6 L;  1K83 L;  1TWH L;  3GTJ L;  2WAQ P;  3I4M L;  3S2H L;  2NVX L;  5FLM L;  2JA7 L;  5IYB L;  2NVT L;  5IP9 L;  3HOZ L;  5M5X L;  3S15 L;  5C3E L;  3H3V M;  2E2I L;  1I50 L;  3S17 L;  4Y52 L;  4A3K L;  1I3Q L;  3K7A L;  4A3M L;  5M5W L;  2R7Z L;  1TWF L;  4A3L L;  2PMZ P;  3S1R L;  5M3M L;  4A3I L;  3GTK L;  3M4O L;  3PO2 L;  3HOX L;  3GTG L;  5C4J L;  3S14 L;  2NVQ L;  2R92 L;  3S1M L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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