4A3CL

Rna polymerase ii initial transcribing complex with a 5nt dna-rna hybrid
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
molecule tags Transcription
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4a3cL00
2R92L 2R93L 3RZOL 2Y0SP 4Y7NL 5IP9L 3S16L 1TWCL 4C3IL 3M3YL 4A3BL 3H3VM 2NVQL 1Y1VL 2E2JL 3HOVL 2E2HL 2B63L 1I6HL 2WB1P 4A3LL 4Y52L 3FKIL 3PO3L 4X6AL 5M5YL 3HOWL 3I4ML 5C44L 1K83L 4A3FL 4BBSL 3GTJL 3HOXL 3HKZP 5C4JL 3GTQL 3K7AL 3RZDL 2PMZP 4A3EL 5FJ8L 3S2HL 1I50L 2WAQP 4A3CL 4C3HL 3H0GL 1SFOL 1I3QL 5M3FL 2NVTL 4C2M1 2NVYL 3S1QL 3M4OL 3S15L 5M5WL 2JA5L 4A3JL 4AYBP 3HOYL 1TWHL 3S2DL 1TWFL 4QIWP 1TWAL 2R7ZL 4A3ML 2YU9L 2JA8L 1Y1WL 3CQZL 3GTGL 3S1ML 3GTML 3HOUL 4BY7L 3S1RL 5IYCL 5FLML 3GTOL 4A3KL 4BBRL 2VUML 3GTPL 3I4NL 4A3GL 5IYBL 2JA6L 1TWGL 4C3JL 5C3EL 4BXXL 5IP7L 5IYDL 4BY1L 4A93L 3S1NL 5M5XL 3PO2L 2JA7L 2E2IL 3S17L 1R9TL 5C4XL 5M3ML 4A3IL 3HOZL 4A3DL 3GTKL 3GTLL 2NVXL 1WCML 3S14L
chains in the Genus database with same CATH superfamily
2QL0A 1ODHA 3RZOL 1RYTA 5IP9L 2PVXA 1R0GA 1LKOA 2NVQL 5EIOC 2BE5D 2H12A 1NXGA 1I6HL 2EY4E 2MS3A 5C44L 1K83L 4BBSL 1SMUA 4JADA 3HKZP 1VCXA 3K7AL 1R0FA 3RZDL 5FJ8L 3S2HL 4ZN1B 1FHMA 2VL6A 2WAQP 1FHHA 7RXNA 4RXNA 4XXBB 1LKMA 1LTLA 2NVYL 3LWQB 5M5WL 4AI3A 2R7ZL 2YU9L 3P2AA 3CQZL 3IU3I 3GTGL 3HOUL 1QYBA 3GTOL 4A3KL 2ZIXA 4GS7D 4A3GL 1OWBA 2C6BA 5K2ME 3J7Z1 4WFN1 2AYJA 4C3JL 2B5ID 3FDJA 3LWOB 3K35A 5H1Sc 2JA7L 3NFPI 2PYAA 2C6AA 4G6BA 2XJTA 1R9TL 2KKDA 2K2DA 5M3ML 4A3IL 8RXNA 1LKPA 4AR4A 1OWCA 4A3DL 5DM61 2XJQA 4XGHA 4LHLA 3PKJA 2RDVA 2M4VA 2R92L 2R93L 5GADc 2Y0SP 4JAEA 5MLC3 2JI1A 1PFYA 3S16L 3PKIA 1PFVA 2LCQA 1VZHA 2PSMC 3M3YL 1NNQA 2E2JL 2AQCA 1BFYA 1PFWA 1RDGA 4E6YA 3SS2A 3FKIL 2HR5A 2PPTA 2CR8A 2M6OA 2M6PA 1RDVA 4X6AL 4AR3A 3HOWL 4POFA 2PVEA 4A3FL 4AI1A 3GTQL 1CAAA 2CKCA 1C09A 2CKAA 1F4LA 4AHXA 4AI0A 4A3CL 2RFKB 4K9FA 6RXNA 1SFOL 4C2M1 3S1QL 1T9PA 1B2JA 2L0ZA 4A3JL 4AYBP 1TWHL 2APOB 1TWFL 1R0IA 3PIP1 3KYWA 1S2ZA 4AI2A 4U671 3S1ML 4YWMA 2Z3QB 2GMGA 1BE7A 4BBRL 2ERJA 1DVBA 3I4NL 4B8CD 1B13A 5C3EL 5IYDL 5MFPA 3S1NL 5GAHc 3A44A 5RXNA 3S17L 3RZ6A 2XJVA 5AN9H 4JAFA 3GTLL 1IROA 1BQ9A 2NVXL 4AHZA 1YK4A 1WCML 5AI3A 2XJRA 5GAEc 2ERSA 1TWCL 2A6HD 4LHNA 3HAXC 5MGNA 3H3VM 2Z3RB 1Y1VL 1ZRPA 1YUXA 2E2HL 1RB9A 1T9QA 2XJPA 1T9OA 3WWLA 2A6ED 1R0HA 3PO3L 5M5YL 3LWRB 3I4ML 2V0EA 3GTJL 1P7PA 5GAGc 3KYXA 1VZGA 4JAGA 4AHYA 3PWFA 2PMZP 1I50L 5IY0A 4AR6A 3LNLA 3H0GL 3JR7A 1I3QL 5M3FL 2NVTL 3LWPB 4AR5A 3HOYL 1YK5A 2V0FA 4QIWP 1PFUA 1H7VA 2A68D 3KYYA 5JVH1 1IRNA 3GTML 1BRFA 4BY7L 5MFZA 1PZXA 2XJSA 3HJWB 3H9BA 2DSXA 3H99A 2JA6L 2KN9A 1NXEA 4BXXL 4BY1L 3PL5A 4A93L 1YV1A 2E2IL 4ME3A 5JVG1 1S24A 5C4XL 3WWNB 4POGA 3QQCE 1IW7D 1VZIA 2NYDA 1S30A 3MSUA 4YWLA 3RZTA 2HVYC 1B2OA 2J9UB 3VPBE 2V3BB 2AUSB 1SMWA 3HJYB 2A69D 3H97A 3J7Y1 4Y7NL 1CADA 1RWDA 4C3IL 4A3BL 3B0AB 1DX8A 1IU5A 3HOVL 2B63L 5DM71 1QCVA 2WB1P 4A3LL 4Y52L 1RYQA 5EINC 3QVDA 3ZG6A 3HOXL 3PZAA 5C4JL 1IU6A 4TVMA 4A3EL 1JYBA 2M4YA 2O5JD 4C3HL 3LWVB 3M4OL 3S15L 1BQ8A 3P8BA 2JA5L 3PIO1 5AI2A 3S2DL 3KYVA 3LPEB 3H9CA 1R0JA 4AHWA 1TWAL 4V196 1B71A 4A3ML 1Z92B 3MPSA 2JA8L 1Y1WL 2XJUA 3S1RL 3MQKB 5IYCL 5FLML 2VUML 3GTPL 5MF6A 5IYBL 2JI2A 2JI3A 3B08B 4TPUA 4UY81 1TWGL 1SMMA 5IP7L 5M5XL 3PO2L 3HOZL 1WJVA 3GTKL 3RYGA 1E8JA 4ZN3B 1QQTA 3KYUA 1YUZA 3S14L
chains in the Genus database with same CATH topology
2R92L 2R93L 3RZOL 2Y0SP 4Y7NL 5IP9L 3S16L 1TWCL 4C3IL 3M3YL 4A3BL 3H3VM 2NVQL 1Y1VL 2E2JL 3HOVL 2E2HL 2B63L 1I6HL 2WB1P 4A3LL 4Y52L 3FKIL 3PO3L 4X6AL 5M5YL 3HOWL 3I4ML 5C44L 1K83L 4A3FL 4BBSL 3GTJL 3HOXL 3HKZP 5C4JL 3GTQL 3K7AL 3RZDL 2PMZP 4A3EL 5FJ8L 3S2HL 1I50L 2WAQP 4A3CL 4C3HL 3H0GL 1SFOL 1I3QL 5M3FL 2NVTL 4C2M1 2NVYL 3S1QL 3M4OL 3S15L 5M5WL 2JA5L 4A3JL 4AYBP 3HOYL 1TWHL 3S2DL 1TWFL 4QIWP 1TWAL 2R7ZL 4A3ML 2YU9L 2JA8L 1Y1WL 3CQZL 3GTGL 3S1ML 3GTML 3HOUL 4BY7L 3S1RL 5IYCL 5FLML 3GTOL 4A3KL 4BBRL 2VUML 3GTPL 3I4NL 4A3GL 5IYBL 2JA6L 1TWGL 4C3JL 5C3EL 4BXXL 5IP7L 5IYDL 4BY1L 4A93L 3S1NL 5M5XL 3PO2L 2JA7L 2E2IL 3S17L 1R9TL 5C4XL 5M3ML 4A3IL 3HOZL 4A3DL 3GTKL 3GTLL 2NVXL 1WCML 3S14L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R92 L;  2R93 L;  3RZO L;  2Y0S P;  4Y7N L;  5IP9 L;  3S16 L;  1TWC L;  4C3I L;  3M3Y L;  4A3B L;  3H3V M;  2NVQ L;  1Y1V L;  2E2J L;  3HOV L;  2E2H L;  2B63 L;  1I6H L;  2WB1 P;  4A3L L;  4Y52 L;  3FKI L;  3PO3 L;  4X6A L;  5M5Y L;  3HOW L;  3I4M L;  5C44 L;  1K83 L;  4A3F L;  4BBS L;  3GTJ L;  3HOX L;  3HKZ P;  5C4J L;  3GTQ L;  3K7A L;  3RZD L;  2PMZ P;  4A3E L;  5FJ8 L;  3S2H L;  1I50 L;  2WAQ P;  4A3C L;  4C3H L;  3H0G L;  1SFO L;  1I3Q L;  5M3F L;  2NVT L;  4C2M 1;  2NVY L;  3S1Q L;  3M4O L;  3S15 L;  5M5W L;  2JA5 L;  4A3J L;  4AYB P;  3HOY L;  1TWH L;  3S2D L;  1TWF L;  4QIW P;  1TWA L;  2R7Z L;  4A3M L;  2YU9 L;  2JA8 L;  1Y1W L;  3CQZ L;  3GTG L;  3S1M L;  3GTM L;  3HOU L;  4BY7 L;  3S1R L;  5IYC L;  5FLM L;  3GTO L;  4A3K L;  4BBR L;  2VUM L;  3GTP L;  3I4N L;  4A3G L;  5IYB L;  2JA6 L;  1TWG L;  4C3J L;  5C3E L;  4BXX L;  5IP7 L;  5IYD L;  4BY1 L;  4A93 L;  3S1N L;  5M5X L;  3PO2 L;  2JA7 L;  2E2I L;  3S17 L;  1R9T L;  5C4X L;  5M3M L;  4A3I L;  3HOZ L;  4A3D L;  3GTK L;  3GTL L;  2NVX L;  1WCM L;  3S14 L; 
#chains in the Genus database with same CATH topology
 2QL0 A;  1ODH A;  3RZO L;  1RYT A;  5IP9 L;  2PVX A;  1R0G A;  1LKO A;  2NVQ L;  5EIO C;  2BE5 D;  2H12 A;  1NXG A;  1I6H L;  2EY4 E;  2MS3 A;  5C44 L;  1K83 L;  4BBS L;  1SMU A;  4JAD A;  3HKZ P;  1VCX A;  3K7A L;  1R0F A;  3RZD L;  5FJ8 L;  3S2H L;  4ZN1 B;  1FHM A;  2VL6 A;  2WAQ P;  1FHH A;  7RXN A;  4RXN A;  4XXB B;  1LKM A;  1LTL A;  2NVY L;  3LWQ B;  5M5W L;  4AI3 A;  2R7Z L;  2YU9 L;  3P2A A;  3CQZ L;  3IU3 I;  3GTG L;  3HOU L;  1QYB A;  3GTO L;  4A3K L;  2ZIX A;  4GS7 D;  4A3G L;  1OWB A;  2C6B A;  5K2M E;  3J7Z 1;  4WFN 1;  2AYJ A;  4C3J L;  2B5I D;  3FDJ A;  3LWO B;  3K35 A;  5H1S c;  2JA7 L;  3NFP I;  2PYA A;  2C6A A;  4G6B A;  2XJT A;  1R9T L;  2KKD A;  2K2D A;  5M3M L;  4A3I L;  8RXN A;  1LKP A;  4AR4 A;  1OWC A;  4A3D L;  5DM6 1;  2XJQ A;  4XGH A;  4LHL A;  3PKJ A;  2RDV A;  2M4V A;  2R92 L;  2R93 L;  5GAD c;  2Y0S P;  4JAE A;  5MLC 3;  2JI1 A;  1PFY A;  3S16 L;  3PKI A;  1PFV A;  2LCQ A;  1VZH A;  2PSM C;  3M3Y L;  1NNQ A;  2E2J L;  2AQC A;  1BFY A;  1PFW A;  1RDG A;  4E6Y A;  3SS2 A;  3FKI L;  2HR5 A;  2PPT A;  2CR8 A;  2M6O A;  2M6P A;  1RDV A;  4X6A L;  4AR3 A;  3HOW L;  4POF A;  2PVE A;  4A3F L;  4AI1 A;  3GTQ L;  1CAA A;  2CKC A;  1C09 A;  2CKA A;  1F4L A;  4AHX A;  4AI0 A;  4A3C L;  2RFK B;  4K9F A;  6RXN A;  1SFO L;  4C2M 1;  3S1Q L;  1T9P A;  1B2J A;  2L0Z A;  4A3J L;  4AYB P;  1TWH L;  2APO B;  1TWF L;  1R0I A;  3PIP 1;  3KYW A;  1S2Z A;  4AI2 A;  4U67 1;  3S1M L;  4YWM A;  2Z3Q B;  2GMG A;  1BE7 A;  4BBR L;  2ERJ A;  1DVB A;  3I4N L;  4B8C D;  1B13 A;  5C3E L;  5IYD L;  5MFP A;  3S1N L;  5GAH c;  3A44 A;  5RXN A;  3S17 L;  3RZ6 A;  2XJV A;  5AN9 H;  4JAF A;  3GTL L;  1IRO A;  1BQ9 A;  2NVX L;  4AHZ A;  1YK4 A;  1WCM L;  5AI3 A;  2XJR A;  5GAE c;  2ERS A;  1TWC L;  2A6H D;  4LHN A;  3HAX C;  5MGN A;  3H3V M;  2Z3R B;  1Y1V L;  1ZRP A;  1YUX A;  2E2H L;  1RB9 A;  1T9Q A;  2XJP A;  1T9O A;  3WWL A;  2A6E D;  1R0H A;  3PO3 L;  5M5Y L;  3LWR B;  3I4M L;  2V0E A;  3GTJ L;  1P7P A;  5GAG c;  3KYX A;  1VZG A;  4JAG A;  4AHY A;  3PWF A;  2PMZ P;  1I50 L;  5IY0 A;  4AR6 A;  3LNL A;  3H0G L;  3JR7 A;  1I3Q L;  5M3F L;  2NVT L;  3LWP B;  4AR5 A;  3HOY L;  1YK5 A;  2V0F A;  4QIW P;  1PFU A;  1H7V A;  2A68 D;  3KYY A;  5JVH 1;  1IRN A;  3GTM L;  1BRF A;  4BY7 L;  5MFZ A;  1PZX A;  2XJS A;  3HJW B;  3H9B A;  2DSX A;  3H99 A;  2JA6 L;  2KN9 A;  1NXE A;  4BXX L;  4BY1 L;  3PL5 A;  4A93 L;  1YV1 A;  2E2I L;  4ME3 A;  5JVG 1;  1S24 A;  5C4X L;  3WWN B;  4POG A;  3QQC E;  1IW7 D;  1VZI A;  2NYD A;  1S30 A;  3MSU A;  4YWL A;  3RZT A;  2HVY C;  1B2O A;  2J9U B;  3VPB E;  2V3B B;  2AUS B;  1SMW A;  3HJY B;  2A69 D;  3H97 A;  3J7Y 1;  4Y7N L;  1CAD A;  1RWD A;  4C3I L;  4A3B L;  3B0A B;  1DX8 A;  1IU5 A;  3HOV L;  2B63 L;  5DM7 1;  1QCV A;  2WB1 P;  4A3L L;  4Y52 L;  1RYQ A;  5EIN C;  3QVD A;  3ZG6 A;  3HOX L;  3PZA A;  5C4J L;  1IU6 A;  4TVM A;  4A3E L;  1JYB A;  2M4Y A;  2O5J D;  4C3H L;  3LWV B;  3M4O L;  3S15 L;  1BQ8 A;  3P8B A;  2JA5 L;  3PIO 1;  5AI2 A;  3S2D L;  3KYV A;  3LPE B;  3H9C A;  1R0J A;  4AHW A;  1TWA L;  4V19 6;  1B71 A;  4A3M L;  1Z92 B;  3MPS A;  2JA8 L;  1Y1W L;  2XJU A;  3S1R L;  3MQK B;  5IYC L;  5FLM L;  2VUM L;  3GTP L;  5MF6 A;  5IYB L;  2JI2 A;  2JI3 A;  3B08 B;  4TPU A;  4UY8 1;  1TWG L;  1SMM A;  5IP7 L;  5M5X L;  3PO2 L;  3HOZ L;  1WJV A;  3GTK L;  3RYG A;  1E8J A;  4ZN3 B;  1QQT A;  3KYU A;  1YUZ A;  3S14 L; 
#chains in the Genus database with same CATH homology
 2R92 L;  2R93 L;  3RZO L;  2Y0S P;  4Y7N L;  5IP9 L;  3S16 L;  1TWC L;  4C3I L;  3M3Y L;  4A3B L;  3H3V M;  2NVQ L;  1Y1V L;  2E2J L;  3HOV L;  2E2H L;  2B63 L;  1I6H L;  2WB1 P;  4A3L L;  4Y52 L;  3FKI L;  3PO3 L;  4X6A L;  5M5Y L;  3HOW L;  3I4M L;  5C44 L;  1K83 L;  4A3F L;  4BBS L;  3GTJ L;  3HOX L;  3HKZ P;  5C4J L;  3GTQ L;  3K7A L;  3RZD L;  2PMZ P;  4A3E L;  5FJ8 L;  3S2H L;  1I50 L;  2WAQ P;  4A3C L;  4C3H L;  3H0G L;  1SFO L;  1I3Q L;  5M3F L;  2NVT L;  4C2M 1;  2NVY L;  3S1Q L;  3M4O L;  3S15 L;  5M5W L;  2JA5 L;  4A3J L;  4AYB P;  3HOY L;  1TWH L;  3S2D L;  1TWF L;  4QIW P;  1TWA L;  2R7Z L;  4A3M L;  2YU9 L;  2JA8 L;  1Y1W L;  3CQZ L;  3GTG L;  3S1M L;  3GTM L;  3HOU L;  4BY7 L;  3S1R L;  5IYC L;  5FLM L;  3GTO L;  4A3K L;  4BBR L;  2VUM L;  3GTP L;  3I4N L;  4A3G L;  5IYB L;  2JA6 L;  1TWG L;  4C3J L;  5C3E L;  4BXX L;  5IP7 L;  5IYD L;  4BY1 L;  4A93 L;  3S1N L;  5M5X L;  3PO2 L;  2JA7 L;  2E2I L;  3S17 L;  1R9T L;  5C4X L;  5M3M L;  4A3I L;  3HOZ L;  4A3D L;  3GTK L;  3GTL L;  2NVX L;  1WCM L;  3S14 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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