1TWGL

Rna polymerase ii complexed with ctp
Total Genus 0
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
0
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase II largest subunit
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2004-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 1twgL00
3H0GL 3FKIL 4A3LL 4A3ML 4A3JL 5IYBL 5FLML 4A93L 3I4NL 1TWHL 1R9TL 5IYDL 3GTJL 2JA5L 1TWAL 1SFOL 4A3KL 3S1RL 4BXXL 1I3QL 3S2DL 1Y1WL 3HOZL 3S2HL 4C3JL 3GTML 3S1QL 4BY7L 3GTLL 4A3FL 3I4ML 2B63L 2R93L 4X6AL 4C2M1 4AYBP 2NVTL 2E2HL 1I6HL 2E2IL 3GTGL 3GTQL 3HKZP 4A3CL 3HOVL 3S1ML 1TWGL 5M5WL 3CQZL 3S17L 2PMZP 4QIWP 4BBRL 5C4JL 3HOWL 2JA6L 1K83L 3PO3L 4A3GL 2NVXL 5IYCL 3S14L 3H3VM 3RZOL 3PO2L 2Y0SP 4BY1L 1TWCL 2WAQP 5C4XL 1WCML 5IP7L 4A3EL 5IP9L 1I50L 2R7ZL 5C44L 3GTKL 3M3YL 5M3FL 4A3IL 5M5XL 3S16L 3M4OL 2WB1P 1TWFL 3GTOL 2VUML 4Y52L 4A3BL 4C3HL 2E2JL 3S15L 3GTPL 3RZDL 3S1NL 3K7AL 2R92L 5FJ8L 1Y1VL 2YU9L 5C3EL 4A3DL 2JA7L 4Y7NL 3HOUL 5M3ML 3HOXL 4C3IL 3HOYL 2JA8L 5M5YL 2NVQL 4BBSL 2NVYL
chains in the Genus database with same CATH superfamily
1RYQA 3HJYB 2A68D 5IYBL 5FLML 2J9UB 3KYXA 3GTJL 1SMUA 2XJUA 2JA5L 1S24A 5IY0A 5RXNA 3S2DL 3MSUA 1Y1WL 3S2HL 4JAEA 3GTLL 4A3FL 2R93L 2HVYC 1JYBA 4XGHA 4POFA 1YK5A 2PPTA 2VL6A 3S1ML 1TWGL 5M5WL 3B08B 3S17L 4UY81 4BBRL 3HOWL 5MLC3 1C09A 2JI2A 1ODHA 4V196 2JA6L 3PO3L 3IU3I 3K35A 4AHXA 3MQKB 1VCXA 1B71A 3PZAA 2Y0SP 1B2JA 1WJVA 1TWCL 1QYBA 4AR6A 2V0EA 3QQCE 5C44L 3PWFA 3VPBE 1S30A 3M4OL 5MF6A 1DVBA 2HR5A 4C3HL 2V0FA 3WWLA 1H7VA 4AI1A 1LKPA 5FJ8L 1T9OA 4AHZA 3QVDA 1SMMA 1NNQA 5C3EL 2JA7L 5MFZA 4WFN1 1BFYA 1FHHA 2M6OA 2XJSA 4AI0A 1P7PA 2CKCA 1SMWA 1VZHA 3FKIL 3MPSA 3KYUA 2EY4E 4AR4A 4A93L 1YUZA 2A6ED 2M4YA 3I4NL 2A6HD 5IYDL 2ERSA 1SFOL 4A3KL 3PKIA 4BXXL 3GTML 2B5ID 3H9BA 3H97A 4X6AL 4AYBP 2NVTL 3H99A 4GS7D 4TVMA 3CQZL 2M6PA 3LWVB 5AI2A 1BQ9A 1VZGA 6RXNA 1R0HA 2XJPA 2ZIXA 5EIOC 2NYDA 2CR8A 1NXGA 4RXNA 4A3GL 3P2AA 2CKAA 1IU5A 2PYAA 3RZOL 5JVG1 5DM71 1Z92B 3A44A 5C4XL 1IROA 4A3EL 1I50L 2R7ZL 3GTKL 3M3YL 1RDGA 1BRFA 5M3FL 1PFUA 2Z3QB 2VUML 2XJQA 4K9FA 5AN9H 4A3BL 2BE5D 4AR5A 4E6YA 3RZDL 3K7AL 5EINC 2R92L 1Y1VL 4AI3A 2YU9L 1R0FA 1T9QA 4A3DL 3KYYA 4Y7NL 1FHMA 1VZIA 5M3ML 3LWPB 2H12A 4JADA 2V3BB 4C3IL 5GAEc 4BBSL 2DSXA 3H0GL 3P8BA 4A3LL 4A3ML 4ZN1B 1BE7A 2LCQA 3LWOB 4AHWA 2APOB 3PIP1 2KKDA 3JR7A 2MS3A 5DM61 4AR3A 5GAHc 2ERJA 1I3QL 1PFYA 5MFPA 4C3JL 4BY7L 2RFKB 2E2HL 2Z3RB 1I6HL 3KYWA 3PKJA 3GTGL 2AUSB 3GTQL 3HKZP 4A3CL 3HOVL 1PFWA 2C6AA 1IU6A 1CADA 4XXBB 1YV1A 1YUXA 3ZG6A 3J7Y1 2PMZP 5GADc 1R0IA 1DX8A 5C4JL 1RWDA 1K83L 3FDJA 2XJVA 3S14L 3H3VM 2GMGA 4LHLA 1PZXA 1B2OA 3LPEB 4BY1L 2WAQP 1WCML 2C6BA 5AI3A 5K2ME 2K2DA 2WB1P 1RB9A 5JVH1 3GTPL 3LNLA 3S1NL 2JI3A 2M4VA 3LWQB 1E8JA 4ME3A 2AYJA 3HOXL 1PFVA 2JA8L 5M5YL 4B8CD 2A69D 3SS2A 1IW7D 1BQ8A 3PIO1 4A3JL 4AHYA 1TWHL 4TPUA 1R9TL 2JI1A 3WWNB 1TWAL 3H9CA 3KYVA 3S1RL 3HOZL 4YWMA 3S1QL 3I4ML 2B63L 4JAFA 4C2M1 3RZ6A 1R0GA 4AI2A 2E2IL 2PVEA 2RDVA 1YK4A 2AQCA 1LTLA 1LKOA 7RXNA 2KN9A 1S2ZA 4QIWP 4YWLA 2QL0A 3RYGA 4ZN3B 5H1Sc 1QCVA 8RXNA 1ZRPA 2NVXL 5IYCL 3RZTA 1IRNA 3NFPI 2PVXA 2L0ZA 3PO2L 4JAGA 4U671 5IP7L 5IP9L 3B0AB 3HAXC 1F4LA 1R0JA 1RYTA 1RDVA 1OWBA 4A3IL 5M5XL 2XJTA 1QQTA 3S16L 1OWCA 4G6BA 4POGA 2O5JD 1TWFL 3GTOL 4Y52L 2XJRA 2E2JL 3S15L 5GAGc 1T9PA 3HJWB 1LKMA 3LWRB 1CAAA 4LHNA 3HOUL 1B13A 1NXEA 3PL5A 3HOYL 2NVQL 3J7Z1 5MGNA 2NVYL 2PSMC
chains in the Genus database with same CATH topology
3H0GL 3FKIL 4A3LL 4A3ML 4A3JL 5IYBL 5FLML 4A93L 3I4NL 1TWHL 1R9TL 5IYDL 3GTJL 2JA5L 1TWAL 1SFOL 4A3KL 3S1RL 4BXXL 1I3QL 3S2DL 1Y1WL 3HOZL 3S2HL 4C3JL 3GTML 3S1QL 4BY7L 3GTLL 4A3FL 3I4ML 2B63L 2R93L 4X6AL 4C2M1 4AYBP 2NVTL 2E2HL 1I6HL 2E2IL 3GTGL 3GTQL 3HKZP 4A3CL 3HOVL 3S1ML 1TWGL 5M5WL 3CQZL 3S17L 2PMZP 4QIWP 4BBRL 5C4JL 3HOWL 2JA6L 1K83L 3PO3L 4A3GL 2NVXL 5IYCL 3S14L 3H3VM 3RZOL 3PO2L 2Y0SP 4BY1L 1TWCL 2WAQP 5C4XL 1WCML 5IP7L 4A3EL 5IP9L 1I50L 2R7ZL 5C44L 3GTKL 3M3YL 5M3FL 4A3IL 5M5XL 3S16L 3M4OL 2WB1P 1TWFL 3GTOL 2VUML 4Y52L 4A3BL 4C3HL 2E2JL 3S15L 3GTPL 3RZDL 3S1NL 3K7AL 2R92L 5FJ8L 1Y1VL 2YU9L 5C3EL 4A3DL 2JA7L 4Y7NL 3HOUL 5M3ML 3HOXL 4C3IL 3HOYL 2JA8L 5M5YL 2NVQL 4BBSL 2NVYL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H0G L;  3FKI L;  4A3L L;  4A3M L;  4A3J L;  5IYB L;  5FLM L;  4A93 L;  3I4N L;  1TWH L;  1R9T L;  5IYD L;  3GTJ L;  2JA5 L;  1TWA L;  1SFO L;  4A3K L;  3S1R L;  4BXX L;  1I3Q L;  3S2D L;  1Y1W L;  3HOZ L;  3S2H L;  4C3J L;  3GTM L;  3S1Q L;  4BY7 L;  3GTL L;  4A3F L;  3I4M L;  2B63 L;  2R93 L;  4X6A L;  4C2M 1;  4AYB P;  2NVT L;  2E2H L;  1I6H L;  2E2I L;  3GTG L;  3GTQ L;  3HKZ P;  4A3C L;  3HOV L;  3S1M L;  1TWG L;  5M5W L;  3CQZ L;  3S17 L;  2PMZ P;  4QIW P;  4BBR L;  5C4J L;  3HOW L;  2JA6 L;  1K83 L;  3PO3 L;  4A3G L;  2NVX L;  5IYC L;  3S14 L;  3H3V M;  3RZO L;  3PO2 L;  2Y0S P;  4BY1 L;  1TWC L;  2WAQ P;  5C4X L;  1WCM L;  5IP7 L;  4A3E L;  5IP9 L;  1I50 L;  2R7Z L;  5C44 L;  3GTK L;  3M3Y L;  5M3F L;  4A3I L;  5M5X L;  3S16 L;  3M4O L;  2WB1 P;  1TWF L;  3GTO L;  2VUM L;  4Y52 L;  4A3B L;  4C3H L;  2E2J L;  3S15 L;  3GTP L;  3RZD L;  3S1N L;  3K7A L;  2R92 L;  5FJ8 L;  1Y1V L;  2YU9 L;  5C3E L;  4A3D L;  2JA7 L;  4Y7N L;  3HOU L;  5M3M L;  3HOX L;  4C3I L;  3HOY L;  2JA8 L;  5M5Y L;  2NVQ L;  4BBS L;  2NVY L; 
#chains in the Genus database with same CATH topology
 1RYQ A;  3HJY B;  2A68 D;  5IYB L;  5FLM L;  2J9U B;  3KYX A;  3GTJ L;  1SMU A;  2XJU A;  2JA5 L;  1S24 A;  5IY0 A;  5RXN A;  3S2D L;  3MSU A;  1Y1W L;  3S2H L;  4JAE A;  3GTL L;  4A3F L;  2R93 L;  2HVY C;  1JYB A;  4XGH A;  4POF A;  1YK5 A;  2PPT A;  2VL6 A;  3S1M L;  1TWG L;  5M5W L;  3B08 B;  3S17 L;  4UY8 1;  4BBR L;  3HOW L;  5MLC 3;  1C09 A;  2JI2 A;  1ODH A;  4V19 6;  2JA6 L;  3PO3 L;  3IU3 I;  3K35 A;  4AHX A;  3MQK B;  1VCX A;  1B71 A;  3PZA A;  2Y0S P;  1B2J A;  1WJV A;  1TWC L;  1QYB A;  4AR6 A;  2V0E A;  3QQC E;  5C44 L;  3PWF A;  3VPB E;  1S30 A;  3M4O L;  5MF6 A;  1DVB A;  2HR5 A;  4C3H L;  2V0F A;  3WWL A;  1H7V A;  4AI1 A;  1LKP A;  5FJ8 L;  1T9O A;  4AHZ A;  3QVD A;  1SMM A;  1NNQ A;  5C3E L;  2JA7 L;  5MFZ A;  4WFN 1;  1BFY A;  1FHH A;  2M6O A;  2XJS A;  4AI0 A;  1P7P A;  2CKC A;  1SMW A;  1VZH A;  3FKI L;  3MPS A;  3KYU A;  2EY4 E;  4AR4 A;  4A93 L;  1YUZ A;  2A6E D;  2M4Y A;  3I4N L;  2A6H D;  5IYD L;  2ERS A;  1SFO L;  4A3K L;  3PKI A;  4BXX L;  3GTM L;  2B5I D;  3H9B A;  3H97 A;  4X6A L;  4AYB P;  2NVT L;  3H99 A;  4GS7 D;  4TVM A;  3CQZ L;  2M6P A;  3LWV B;  5AI2 A;  1BQ9 A;  1VZG A;  6RXN A;  1R0H A;  2XJP A;  2ZIX A;  5EIO C;  2NYD A;  2CR8 A;  1NXG A;  4RXN A;  4A3G L;  3P2A A;  2CKA A;  1IU5 A;  2PYA A;  3RZO L;  5JVG 1;  5DM7 1;  1Z92 B;  3A44 A;  5C4X L;  1IRO A;  4A3E L;  1I50 L;  2R7Z L;  3GTK L;  3M3Y L;  1RDG A;  1BRF A;  5M3F L;  1PFU A;  2Z3Q B;  2VUM L;  2XJQ A;  4K9F A;  5AN9 H;  4A3B L;  2BE5 D;  4AR5 A;  4E6Y A;  3RZD L;  3K7A L;  5EIN C;  2R92 L;  1Y1V L;  4AI3 A;  2YU9 L;  1R0F A;  1T9Q A;  4A3D L;  3KYY A;  4Y7N L;  1FHM A;  1VZI A;  5M3M L;  3LWP B;  2H12 A;  4JAD A;  2V3B B;  4C3I L;  5GAE c;  4BBS L;  2DSX A;  3H0G L;  3P8B A;  4A3L L;  4A3M L;  4ZN1 B;  1BE7 A;  2LCQ A;  3LWO B;  4AHW A;  2APO B;  3PIP 1;  2KKD A;  3JR7 A;  2MS3 A;  5DM6 1;  4AR3 A;  5GAH c;  2ERJ A;  1I3Q L;  1PFY A;  5MFP A;  4C3J L;  4BY7 L;  2RFK B;  2E2H L;  2Z3R B;  1I6H L;  3KYW A;  3PKJ A;  3GTG L;  2AUS B;  3GTQ L;  3HKZ P;  4A3C L;  3HOV L;  1PFW A;  2C6A A;  1IU6 A;  1CAD A;  4XXB B;  1YV1 A;  1YUX A;  3ZG6 A;  3J7Y 1;  2PMZ P;  5GAD c;  1R0I A;  1DX8 A;  5C4J L;  1RWD A;  1K83 L;  3FDJ A;  2XJV A;  3S14 L;  3H3V M;  2GMG A;  4LHL A;  1PZX A;  1B2O A;  3LPE B;  4BY1 L;  2WAQ P;  1WCM L;  2C6B A;  5AI3 A;  5K2M E;  2K2D A;  2WB1 P;  1RB9 A;  5JVH 1;  3GTP L;  3LNL A;  3S1N L;  2JI3 A;  2M4V A;  3LWQ B;  1E8J A;  4ME3 A;  2AYJ A;  3HOX L;  1PFV A;  2JA8 L;  5M5Y L;  4B8C D;  2A69 D;  3SS2 A;  1IW7 D;  1BQ8 A;  3PIO 1;  4A3J L;  4AHY A;  1TWH L;  4TPU A;  1R9T L;  2JI1 A;  3WWN B;  1TWA L;  3H9C A;  3KYV A;  3S1R L;  3HOZ L;  4YWM A;  3S1Q L;  3I4M L;  2B63 L;  4JAF A;  4C2M 1;  3RZ6 A;  1R0G A;  4AI2 A;  2E2I L;  2PVE A;  2RDV A;  1YK4 A;  2AQC A;  1LTL A;  1LKO A;  7RXN A;  2KN9 A;  1S2Z A;  4QIW P;  4YWL A;  2QL0 A;  3RYG A;  4ZN3 B;  5H1S c;  1QCV A;  8RXN A;  1ZRP A;  2NVX L;  5IYC L;  3RZT A;  1IRN A;  3NFP I;  2PVX A;  2L0Z A;  3PO2 L;  4JAG A;  4U67 1;  5IP7 L;  5IP9 L;  3B0A B;  3HAX C;  1F4L A;  1R0J A;  1RYT A;  1RDV A;  1OWB A;  4A3I L;  5M5X L;  2XJT A;  1QQT A;  3S16 L;  1OWC A;  4G6B A;  4POG A;  2O5J D;  1TWF L;  3GTO L;  4Y52 L;  2XJR A;  2E2J L;  3S15 L;  5GAG c;  1T9P A;  3HJW B;  1LKM A;  3LWR B;  1CAA A;  4LHN A;  3HOU L;  1B13 A;  1NXE A;  3PL5 A;  3HOY L;  2NVQ L;  3J7Z 1;  5MGN A;  2NVY L;  2PSM C; 
#chains in the Genus database with same CATH homology
 3H0G L;  3FKI L;  4A3L L;  4A3M L;  4A3J L;  5IYB L;  5FLM L;  4A93 L;  3I4N L;  1TWH L;  1R9T L;  5IYD L;  3GTJ L;  2JA5 L;  1TWA L;  1SFO L;  4A3K L;  3S1R L;  4BXX L;  1I3Q L;  3S2D L;  1Y1W L;  3HOZ L;  3S2H L;  4C3J L;  3GTM L;  3S1Q L;  4BY7 L;  3GTL L;  4A3F L;  3I4M L;  2B63 L;  2R93 L;  4X6A L;  4C2M 1;  4AYB P;  2NVT L;  2E2H L;  1I6H L;  2E2I L;  3GTG L;  3GTQ L;  3HKZ P;  4A3C L;  3HOV L;  3S1M L;  1TWG L;  5M5W L;  3CQZ L;  3S17 L;  2PMZ P;  4QIW P;  4BBR L;  5C4J L;  3HOW L;  2JA6 L;  1K83 L;  3PO3 L;  4A3G L;  2NVX L;  5IYC L;  3S14 L;  3H3V M;  3RZO L;  3PO2 L;  2Y0S P;  4BY1 L;  1TWC L;  2WAQ P;  5C4X L;  1WCM L;  5IP7 L;  4A3E L;  5IP9 L;  1I50 L;  2R7Z L;  5C44 L;  3GTK L;  3M3Y L;  5M3F L;  4A3I L;  5M5X L;  3S16 L;  3M4O L;  2WB1 P;  1TWF L;  3GTO L;  2VUM L;  4Y52 L;  4A3B L;  4C3H L;  2E2J L;  3S15 L;  3GTP L;  3RZD L;  3S1N L;  3K7A L;  2R92 L;  5FJ8 L;  1Y1V L;  2YU9 L;  5C3E L;  4A3D L;  2JA7 L;  4Y7N L;  3HOU L;  5M3M L;  3HOX L;  4C3I L;  3HOY L;  2JA8 L;  5M5Y L;  2NVQ L;  4BBS L;  2NVY L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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