2Z3RB

Crystal structure of the il-15/il-15ra complex
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
74
structure length
74
Chain Sequence
SITCPPPMSVEHADIWVKSYSLYSRERYICNSGFKRKAGTSSLTECVLNKATNVAHWTTPSLKCIRDPALVHQR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans
pubmed doi rcsb
molecule tags Cytokine/cytokine receptor
source organism Homo sapiens
molecule keywords Interleukin-15
total genus 13
structure length 74
sequence length 74
chains with identical sequence D, F, H, J, L, N, P
ec nomenclature
pdb deposition date 2007-06-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.230 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2z3rB01
3NFPI 4GS7D 2ERJA 2Z3RB 2Z3QB 3IU3I 1Z92B 2B5ID 2PSMC 2ERSA
chains in the Genus database with same CATH superfamily
7RXNA 2E2HL 8RXNA 1TWFL 5M3ML 5AI2A 3K35A 3QQCE 1IU6A 2NVTL 3PIO1 3IU3I 5FJ8L 3P2AA 2JI2A 2PPTA 2CKAA 3J7Y1 4A3KL 2VL6A 5K2ME 1VZGA 4A3IL 2KN9A 3LWQB 4ZN3B 1WJVA 3HJWB 1Y1VL 4XXBB 2WB1P 3A44A 3M3YL 4Y52L 3S2HL 3MQKB 3PIP1 5FLML 1IRNA 1RDGA 1BQ9A 3KYYA 5H1Sc 3LWRB 1NXEA 4AR4A 3FDJA 2JI1A 3NFPI 4LHLA 4RXNA 4AHYA 1R0JA 5MF6A 4AHZA 4A3ML 2RFKB 4B8CD 1S30A 2V0FA 3S2DL 5MLC3 2B63L 5IP7L 2XJPA 4BY1L 1LKOA 3I4NL 1RDVA 2R7ZL 3ZG6A 3HOYL 3GTKL 1QQTA 3H9BA 4LHNA 2C6AA 4WFN1 2V0EA 2R92L 3GTML 3KYVA 2XJSA 4BBRL 4A3BL 1CAAA 5IP9L 1I3QL 3P8BA 2KKDA 4C3HL 5DM71 4YWMA 2QL0A 3PL5A 4C3IL 1LKMA 1OWCA 1DX8A 1TWHL 3GTLL 3FKIL 5IYBL 2A68D 5DM61 2PVXA 1C09A 3GTJL 2E2JL 2A6ED 4A3LL 3H97A 1BFYA 4AYBP 1VCXA 5IYCL 1WCML 3PKIA 3SS2A 1SMMA 5M5WL 1B71A 3LWVB 3H3VM 1BQ8A 5M5XL 3S17L 1YV1A 2M4YA 3H99A 3HOVL 5GAHc 2M6PA 1QYBA 4JADA 1RWDA 3HOZL 3KYWA 1ZRPA 1LKPA 2HVYC 1RYQA 4JAFA 5RXNA 1IU5A 5MFZA 2C6BA 1TWAL 4C3JL 3PWFA 1LTLA 4AHWA 2AQCA 1FHHA 1F4LA 1S2ZA 4A3FL 3S15L 3HOWL 2H12A 5MFPA 2M4VA 2B5ID 2PSMC 3LNLA 3K7AL 4BY7L 6RXNA 4YWLA 2Z3RB 3S16L 2L0ZA 3HJYB 4TPUA 2M6OA 1VZIA 3GTOL 2XJQA 4AI1A 2Z3QB 4TVMA 2JA6L 2PVEA 2DSXA 4A3EL 2JA5L 3I4ML 1T9PA 1FHMA 1BRFA 3M4OL 4K9FA 4AHXA 1I6HL 4ZN1B 1YK5A 4BXXL 2V3BB 4AR5A 4X6AL 4A3DL 4G6BA 1PZXA 1TWCL 3PZAA 1ODHA 2YU9L 1PFWA 3S14L 3S1ML 5GADc 2AYJA 2A6HD 1YUZA 2APOB 1R9TL 2O5JD 4AR6A 4JAGA 2JA7L 2NVYL 1NXGA 1R0IA 3LWOB 1S24A 2ERJA 4UY81 1NNQA 2JA8L 2NVXL 4U671 2GMGA 3GTQL 5C4JL 4BBSL 1B2OA 1DVBA 2XJUA 2NYDA 2A69D 4C2M1 3KYXA 1Z92B 3RYGA 3J7Z1 1P7PA 2AUSB 2XJTA 3GTGL 5IYDL 2BE5D 4AR3A 4A3JL 5IY0A 1YUXA 5M3FL 2CKCA 3LWPB 3B0AB 2PMZP 3WWNB 3WWLA 2ERSA 1IW7D 4QIWP 1YK4A 2RDVA 5MGNA 1K83L 4A3GL 3HOXL 1I50L 1CADA 5C3EL 2VUML 3RZDL 3JR7A 3H9CA 4AI2A 5JVH1 2HR5A 3PKJA 1T9OA 1VZHA 3QVDA 2Y0SP 1E8JA 3B08B 4A3CL 2EY4E 1R0FA 5C44L 4JAEA 2JI3A 4V196 1IROA 1Y1WL 2E2IL 1QCVA 1PFVA 1R0GA 1OWBA 1SFOL 3HKZP 1R0HA 4A93L 3MSUA 5M5YL 3HOUL 2XJVA 3S1NL 2LCQA 3S1QL 1PFUA 1BE7A 1H7VA 2MS3A 3H0GL 5EINC 3RZTA 2ZIXA 1B13A 3RZOL 1RB9A 4ME3A 5EIOC 2PYAA 4AI0A 5C4XL 5JVG1 2WAQP 4GS7D 2K2DA 1SMUA 3PO3L 3RZ6A 4POFA 1RYTA 5AI3A 2J9UB 2NVQL 3VPBE 2CR8A 1B2JA 5GAGc 1PFYA 3PO2L 1T9QA 4AI3A 2R93L 4Y7NL 4XGHA 3MPSA 3S1RL 2XJRA 3KYUA 4POGA 5GAEc 1JYBA 3HAXC 3CQZL 5AN9H 1SMWA 1TWGL 3GTPL 4E6YA 3LPEB
chains in the Genus database with same CATH topology
7RXNA 1C09A 1T9PA 1FHMA 4AI2A 2A6ED 8RXNA 1BRFA 5JVH1 1BFYA 2HR5A 4K9FA 5AI2A 1VCXA 4AHXA 3PKJA 3K35A 1T9OA 4ZN1B 1VZHA 3QQCE 1IU6A 3PKIA 3SS2A 1SMMA 1YK5A 3QVDA 1E8JA 2V3BB 3B08B 3PIO1 3IU3I 3P2AA 1B71A 2JI2A 2PPTA 1R0FA 2CKAA 4AR5A 4JAEA 3J7Y1 2JI3A 4G6BA 4V196 1IROA 3PZAA 1QCVA 1ODHA 2VL6A 1BQ8A 1VZGA 5K2ME 1R0GA 1OWBA 2KN9A 4ZN3B 1WJVA 5GADc 1YV1A 1R0HA 2AYJA 2M4YA 2A6HD 5GAHc 2M6PA 1YUZA 2O5JD 3MSUA 4XXBB 4AR6A 1QYBA 2XJVA 4JAGA 1NXGA 1R0IA 2LCQA 3A44A 1S24A 1BE7A 2ERJA 1H7VA 2MS3A 4JADA 1RWDA 4UY81 3PIP1 1IRNA 1NNQA 5EINC 1RDGA 3RZTA 3KYWA 1BQ9A 3KYYA 1ZRPA 5H1Sc 2ZIXA 1B13A 1LKPA 1NXEA 4U671 2GMGA 1RB9A 4AR4A 1RYQA 2JI1A 3NFPI 4LHLA 4JAFA 5RXNA 1B2OA 4ME3A 4RXNA 1DVBA 2PYAA 2XJUA 4AI0A 5EIOC 4AHYA 2NYDA 2A69D 1IU5A 5JVG1 1R0JA 4GS7D 5MF6A 5MFZA 4AHZA 3KYXA 2K2DA 1Z92B 1SMUA 2C6BA 3RYGA 3J7Z1 4B8CD 1S30A 3RZ6A 2V0FA 3PWFA 4POFA 5MLC3 2XJTA 2XJPA 1LTLA 1LKOA 1RDVA 1RYTA 3ZG6A 5AI3A 4AHWA 2BE5D 2J9UB 1FHHA 3VPBE 4AR3A 1S2ZA 2CR8A 2C6AA 4LHNA 1B2JA 5IY0A 1YUXA 5GAGc 2CKCA 4WFN1 2H12A 5MFPA 2M4VA 1T9QA 2B5ID 2V0EA 2PSMC 3KYVA 2XJSA 3LNLA 1CAAA 3B0AB 4AI3A 4XGHA 3P8BA 2KKDA 3MPSA 4YWLA 2Z3RB 3WWNB 6RXNA 2L0ZA 3WWLA 5DM71 4YWMA 2ERSA 2QL0A 2XJRA 3KYUA 1IW7D 4TPUA 1LKMA 1YK4A 4POGA 2RDVA 5GAEc 5MGNA 2M6OA 1JYBA 1OWCA 1VZIA 1DX8A 5AN9H 2XJQA 1SMWA 2A68D 2Z3QB 4TVMA 4AI1A 2PVXA 1CADA 5DM61 2PVEA 2DSXA 4E6YA 3LPEB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NFP I;  4GS7 D;  2ERJ A;  2Z3R B;  2Z3Q B;  3IU3 I;  1Z92 B;  2B5I D;  2PSM C;  2ERS A; 
#chains in the Genus database with same CATH topology
 7RXN A;  2E2H L;  8RXN A;  1TWF L;  5M3M L;  5AI2 A;  3K35 A;  3QQC E;  1IU6 A;  2NVT L;  3PIO 1;  3IU3 I;  5FJ8 L;  3P2A A;  2JI2 A;  2PPT A;  2CKA A;  3J7Y 1;  4A3K L;  2VL6 A;  5K2M E;  1VZG A;  4A3I L;  2KN9 A;  3LWQ B;  4ZN3 B;  1WJV A;  3HJW B;  1Y1V L;  4XXB B;  2WB1 P;  3A44 A;  3M3Y L;  4Y52 L;  3S2H L;  3MQK B;  3PIP 1;  5FLM L;  1IRN A;  1RDG A;  1BQ9 A;  3KYY A;  5H1S c;  3LWR B;  1NXE A;  4AR4 A;  3FDJ A;  2JI1 A;  3NFP I;  4LHL A;  4RXN A;  4AHY A;  1R0J A;  5MF6 A;  4AHZ A;  4A3M L;  2RFK B;  4B8C D;  1S30 A;  2V0F A;  3S2D L;  5MLC 3;  2B63 L;  5IP7 L;  2XJP A;  4BY1 L;  1LKO A;  3I4N L;  1RDV A;  2R7Z L;  3ZG6 A;  3HOY L;  3GTK L;  1QQT A;  3H9B A;  4LHN A;  2C6A A;  4WFN 1;  2V0E A;  2R92 L;  3GTM L;  3KYV A;  2XJS A;  4BBR L;  4A3B L;  1CAA A;  5IP9 L;  1I3Q L;  3P8B A;  2KKD A;  4C3H L;  5DM7 1;  4YWM A;  2QL0 A;  3PL5 A;  4C3I L;  1LKM A;  1OWC A;  1DX8 A;  1TWH L;  3GTL L;  3FKI L;  5IYB L;  2A68 D;  5DM6 1;  2PVX A;  1C09 A;  3GTJ L;  2E2J L;  2A6E D;  4A3L L;  3H97 A;  1BFY A;  4AYB P;  1VCX A;  5IYC L;  1WCM L;  3PKI A;  3SS2 A;  1SMM A;  5M5W L;  1B71 A;  3LWV B;  3H3V M;  1BQ8 A;  5M5X L;  3S17 L;  1YV1 A;  2M4Y A;  3H99 A;  3HOV L;  5GAH c;  2M6P A;  1QYB A;  4JAD A;  1RWD A;  3HOZ L;  3KYW A;  1ZRP A;  1LKP A;  2HVY C;  1RYQ A;  4JAF A;  5RXN A;  1IU5 A;  5MFZ A;  2C6B A;  1TWA L;  4C3J L;  3PWF A;  1LTL A;  4AHW A;  2AQC A;  1FHH A;  1F4L A;  1S2Z A;  4A3F L;  3S15 L;  3HOW L;  2H12 A;  5MFP A;  2M4V A;  2B5I D;  2PSM C;  3LNL A;  3K7A L;  4BY7 L;  6RXN A;  4YWL A;  2Z3R B;  3S16 L;  2L0Z A;  3HJY B;  4TPU A;  2M6O A;  1VZI A;  3GTO L;  2XJQ A;  4AI1 A;  2Z3Q B;  4TVM A;  2JA6 L;  2PVE A;  2DSX A;  4A3E L;  2JA5 L;  3I4M L;  1T9P A;  1FHM A;  1BRF A;  3M4O L;  4K9F A;  4AHX A;  1I6H L;  4ZN1 B;  1YK5 A;  4BXX L;  2V3B B;  4AR5 A;  4X6A L;  4A3D L;  4G6B A;  1PZX A;  1TWC L;  3PZA A;  1ODH A;  2YU9 L;  1PFW A;  3S14 L;  3S1M L;  5GAD c;  2AYJ A;  2A6H D;  1YUZ A;  2APO B;  1R9T L;  2O5J D;  4AR6 A;  4JAG A;  2JA7 L;  2NVY L;  1NXG A;  1R0I A;  3LWO B;  1S24 A;  2ERJ A;  4UY8 1;  1NNQ A;  2JA8 L;  2NVX L;  4U67 1;  2GMG A;  3GTQ L;  5C4J L;  4BBS L;  1B2O A;  1DVB A;  2XJU A;  2NYD A;  2A69 D;  4C2M 1;  3KYX A;  1Z92 B;  3RYG A;  3J7Z 1;  1P7P A;  2AUS B;  2XJT A;  3GTG L;  5IYD L;  2BE5 D;  4AR3 A;  4A3J L;  5IY0 A;  1YUX A;  5M3F L;  2CKC A;  3LWP B;  3B0A B;  2PMZ P;  3WWN B;  3WWL A;  2ERS A;  1IW7 D;  4QIW P;  1YK4 A;  2RDV A;  5MGN A;  1K83 L;  4A3G L;  3HOX L;  1I50 L;  1CAD A;  5C3E L;  2VUM L;  3RZD L;  3JR7 A;  3H9C A;  4AI2 A;  5JVH 1;  2HR5 A;  3PKJ A;  1T9O A;  1VZH A;  3QVD A;  2Y0S P;  1E8J A;  3B08 B;  4A3C L;  2EY4 E;  1R0F A;  5C44 L;  4JAE A;  2JI3 A;  4V19 6;  1IRO A;  1Y1W L;  2E2I L;  1QCV A;  1PFV A;  1R0G A;  1OWB A;  1SFO L;  3HKZ P;  1R0H A;  4A93 L;  3MSU A;  5M5Y L;  3HOU L;  2XJV A;  3S1N L;  2LCQ A;  3S1Q L;  1PFU A;  1BE7 A;  1H7V A;  2MS3 A;  3H0G L;  5EIN C;  3RZT A;  2ZIX A;  1B13 A;  3RZO L;  1RB9 A;  4ME3 A;  5EIO C;  2PYA A;  4AI0 A;  5C4X L;  5JVG 1;  2WAQ P;  4GS7 D;  2K2D A;  1SMU A;  3PO3 L;  3RZ6 A;  4POF A;  1RYT A;  5AI3 A;  2J9U B;  2NVQ L;  3VPB E;  2CR8 A;  1B2J A;  5GAG c;  1PFY A;  3PO2 L;  1T9Q A;  4AI3 A;  2R93 L;  4Y7N L;  4XGH A;  3MPS A;  3S1R L;  2XJR A;  3KYU A;  4POG A;  5GAE c;  1JYB A;  3HAX C;  3CQZ L;  5AN9 H;  1SMW A;  1TWG L;  3GTP L;  4E6Y A;  3LPE B; 
#chains in the Genus database with same CATH homology
 7RXN A;  1C09 A;  1T9P A;  1FHM A;  4AI2 A;  2A6E D;  8RXN A;  1BRF A;  5JVH 1;  1BFY A;  2HR5 A;  4K9F A;  5AI2 A;  1VCX A;  4AHX A;  3PKJ A;  3K35 A;  1T9O A;  4ZN1 B;  1VZH A;  3QQC E;  1IU6 A;  3PKI A;  3SS2 A;  1SMM A;  1YK5 A;  3QVD A;  1E8J A;  2V3B B;  3B08 B;  3PIO 1;  3IU3 I;  3P2A A;  1B71 A;  2JI2 A;  2PPT A;  1R0F A;  2CKA A;  4AR5 A;  4JAE A;  3J7Y 1;  2JI3 A;  4G6B A;  4V19 6;  1IRO A;  3PZA A;  1QCV A;  1ODH A;  2VL6 A;  1BQ8 A;  1VZG A;  5K2M E;  1R0G A;  1OWB A;  2KN9 A;  4ZN3 B;  1WJV A;  5GAD c;  1YV1 A;  1R0H A;  2AYJ A;  2M4Y A;  2A6H D;  5GAH c;  2M6P A;  1YUZ A;  2O5J D;  3MSU A;  4XXB B;  4AR6 A;  1QYB A;  2XJV A;  4JAG A;  1NXG A;  1R0I A;  2LCQ A;  3A44 A;  1S24 A;  1BE7 A;  2ERJ A;  1H7V A;  2MS3 A;  4JAD A;  1RWD A;  4UY8 1;  3PIP 1;  1IRN A;  1NNQ A;  5EIN C;  1RDG A;  3RZT A;  3KYW A;  1BQ9 A;  3KYY A;  1ZRP A;  5H1S c;  2ZIX A;  1B13 A;  1LKP A;  1NXE A;  4U67 1;  2GMG A;  1RB9 A;  4AR4 A;  1RYQ A;  2JI1 A;  3NFP I;  4LHL A;  4JAF A;  5RXN A;  1B2O A;  4ME3 A;  4RXN A;  1DVB A;  2PYA A;  2XJU A;  4AI0 A;  5EIO C;  4AHY A;  2NYD A;  2A69 D;  1IU5 A;  5JVG 1;  1R0J A;  4GS7 D;  5MF6 A;  5MFZ A;  4AHZ A;  3KYX A;  2K2D A;  1Z92 B;  1SMU A;  2C6B A;  3RYG A;  3J7Z 1;  4B8C D;  1S30 A;  3RZ6 A;  2V0F A;  3PWF A;  4POF A;  5MLC 3;  2XJT A;  2XJP A;  1LTL A;  1LKO A;  1RDV A;  1RYT A;  3ZG6 A;  5AI3 A;  4AHW A;  2BE5 D;  2J9U B;  1FHH A;  3VPB E;  4AR3 A;  1S2Z A;  2CR8 A;  2C6A A;  4LHN A;  1B2J A;  5IY0 A;  1YUX A;  5GAG c;  2CKC A;  4WFN 1;  2H12 A;  5MFP A;  2M4V A;  1T9Q A;  2B5I D;  2V0E A;  2PSM C;  3KYV A;  2XJS A;  3LNL A;  1CAA A;  3B0A B;  4AI3 A;  4XGH A;  3P8B A;  2KKD A;  3MPS A;  4YWL A;  2Z3R B;  3WWN B;  6RXN A;  2L0Z A;  3WWL A;  5DM7 1;  4YWM A;  2ERS A;  2QL0 A;  2XJR A;  3KYU A;  1IW7 D;  4TPU A;  1LKM A;  1YK4 A;  4POG A;  2RDV A;  5GAE c;  5MGN A;  2M6O A;  1JYB A;  1OWC A;  1VZI A;  1DX8 A;  5AN9 H;  2XJQ A;  1SMW A;  2A68 D;  2Z3Q B;  4TVM A;  4AI1 A;  2PVX A;  1CAD A;  5DM6 1;  2PVE A;  2DSX A;  4E6Y A;  3LPE B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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