1IT6A

Crystal structure of the complex between calyculin a and the catalytic subunit of protein phosphatase 1
Total Genus 109

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
293
structure length
293
Chain Sequence
LNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
AH4 (100-113)EMPTYAH1 (9-18)TII1 (19-22)O1 (95-97)TVIII1 (50-53)S1 (52-55)TVIa1 (81-84)S2 (59-62)S12 (263-266)TI'1 (65-68)S14 (291-296)AH3 (69-79)S3 (87-89)TI1 (114-117)TIV5 (164-167)AH5 (128-134)TIV2 (97-100)AH6 (136-143)AH8 (183-188)S4 (118-120)TI2 (123-126)TIV4 (124-127)AH7 (146-157)S5 (162-165)S6 (169-172)AH10 (229-239)TI'2 (165-168)TIV9 (196-199)AH9 (200-206)TI3 (177-180)TIV8 (190-193)S8 (216-218)TI4 (210-213)TIV10 (213-216)S7 (208-209)TI5 (219-222)S11 (255-258)O2 (247-249)S10 (243-246)3H1 (272-274)TIV11 (258-261)AH2 (32-48)TVIII2 (83-86)TIV7 (172-175)S9 (225-227)TIV12 (269-272)TI7 (286-289)TII2 (23-26)TI'3 (259-262)TI6 (251-254)S13 (280-285)Updating...
connected with : NaN
publication title Crystal structure of the complex between calyculin A and the catalytic subunit of protein phosphatase 1.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords SERINE/THREONINE PROTEIN PHOSPHATASE 1 GAMMA (PP1-GAMMA) CAT
total genus 109
structure length 293
sequence length 293
chains with identical sequence B
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2002-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 1it6A00
3RL3A 2AHDA 4ZVZA 2BCDA 3C5WC 4J6OA 1FJMA 5JPFA 5C1VA 4KBPA 3IVDA 1TCOA 3H67A 3QFMA 3P71C 3QG5C 1V73A 3LL8A 4IYPC 4H2GA 3K7WC 1QFCA 2ZBMA 2HYOA 2WDDA 1OI8A 1HO5A 4O43A 3THNA 4UT3B 2YVTA 3CK2A 4I5NC 4ORBA 2R17A 1M63A 3DW8C 4WWLA 2QJCA 4XPNA 3H66A 4FBKA 4MOYA 2HY1A 4TUGA 3H61A 4V0VA 3HVQA 3IB7A 1AUIA 3EGGA 5F3WA 4OR9A 3QFKA 2WDCA 3QFNA 1S3LA 4LU9A 2A22A 3ZU0A 5JPEA 3PSNA 1HP1A 1S70A 1XZWA 1U32A 4O24A 4H2FA 4ZX2A 5INBA 4TUIA 3RL5A 3T1IA 3E7AA 2GJUA 2XMOA 2QFPA 2O8GA 3ICFA 1WAO1 1S95A 2Q8UA 3RL4A 3IB8A 2P6BA 4MP0A 3EGHA 1IT6A 4B2OA 3H64A 3GVEA 4HD0A 3ZTVA 4UT3A 3K7VC 3N5UA 2BDXA 2Z06A 1UF3A 4NZVA 2Z1AA 4M0VA 1OIDA 1KBPA 2DFJA 2IE3C 1HPUA 3DSCA 3DSDA 1II7A 4V0WA 2WDEA 4LTYA 5IOHA 2NPPC 4ORAA 1Z2WA 1JK7A 1USHA 1MF8A 4IL1A 4UT2A 4KKZA 4H1SA 3QFOA 3V4YA 4H2BA 1G5BA 4YKEA 2IAEC 1OIEA 4FBWA 4JA9A 2NYMC 4F0ZA 4I5LC 3RQZA 4G9JA 1UTEA 3JYFA 3H68A 3AV0A 4Q7FA 1QHWA 2NYLC 3H62B 4O4KA 1S8EA 4ORCA 5DNYA 4DSYA 1SU1A 2HYPA 2KKNA 3H60A 3C9FA 4JA7A 4H2IA 3PSOA 1S3MA 2IE4C 2JOGA 4V0XA 4LACC 3THOB 2O8AA 2WDFA 3FGAC 2BQ8X 4FBQA 5HPEA 3E7BA 4MOVA 5JJTA 2NXFA 5GTUA 3H63A 4DT2A 1Z2XA 3IVEA 4UWQA 3H69A 5B8IA 2QFRA 3AUZA 1T70A 4FCXA 5J28A 4O5GA 1S3NA 1NNWA 4DHLA 5EQVA 3KBPA 1T71A 1W24A 1WARA 3TGHA 4H1YP 1XM7A 2USHA 2Z72A 2CV9A
chains in the Genus database with same CATH superfamily
3RL3A 2AHDA 4ZVZA 2BCDA 3C5WC 4J6OA 1FJMA 5JPFA 3E0JA 5C1VA 4KBPA 3IVDA 1TCOA 3H67A 3QFMA 3P71C 3QG5C 1V73A 3LL8A 4IYPC 4H2GA 3K7WC 1QFCA 2ZBMA 2HYOA 2WDDA 1OI8A 1HO5A 4O43A 3THNA 4UT3B 2YVTA 3CK2A 4I5NC 4ORBA 2R17A 1M63A 3DW8C 4WWLA 2QJCA 4XPNA 3H66A 4FBKA 4MOYA 2HY1A 4TUGA 2ZO9B 3H61A 4V0VA 3HVQA 3IB7A 1AUIA 3EGGA 5F3WA 4OR9A 3QFKA 2WDCA 3QFNA 1S3LA 4LU9A 2A22A 3ZU0A 5JPEA 3PSNA 1HP1A 1S70A 1XZWA 1U32A 4O24A 4H2FA 4ZX2A 5INBA 4TUIA 3RL5A 3T1IA 3E7AA 2GJUA 2XMOA 2QFPA 2O8GA 3ICFA 1WAO1 1S95A 2Q8UA 3RL4A 3IB8A 2P6BA 4MP0A 3EGHA 1IT6A 4B2OA 3H64A 3GVEA 4HD0A 3ZTVA 4UT3A 3K7VC 3N5UA 2BDXA 2Z06A 1UF3A 4NZVA 2Z1AA 4M0VA 1OIDA 1KBPA 2DFJA 2IE3C 1HPUA 3DSCA 3DSDA 2YEQA 1II7A 3FLOA 2WDEA 4V0WA 4LTYA 5IOHA 2NPPC 4ORAA 1Z2WA 1JK7A 1USHA 1MF8A 4IL1A 4UT2A 4KKZA 4H1SA 3QFOA 3V4YA 4H2BA 1G5BA 4YKEA 2IAEC 1OIEA 4FBWA 4JA9A 2NYMC 4F0ZA 4I5LC 3RQZA 4G9JA 1UTEA 3JYFA 3H68A 3AV0A 4Q7FA 1QHWA 2DXNA 2NYLC 3H62B 3D03A 4O4KA 1S8EA 4ORCA 2ZOAA 4DSYA 1SU1A 2HYPA 2KKNA 5DNYA 3H60A 3C9FA 4JA7A 4H2IA 3PSOA 1S3MA 2IE4C 2JOGA 4V0XA 4LACC 3THOB 2O8AA 2WDFA 3FGAC 2BQ8X 4FBQA 5HPEA 3E7BA 4MOVA 2DXLA 5JJTA 2NXFA 5GTUA 3H63A 4DT2A 1Z2XA 3IVEA 4UWQA 3H69A 5B8IA 2QFRA 3AUZA 1T70A 4FCXA 5J28A 4O5GA 1S3NA 1NNWA 4DHLA 5EQVA 3KBPA 1T71A 1W24A 1WARA 3TGHA 4H1YP 1XM7A 2USHA 2Z72A 2CV9A
chains in the Genus database with same CATH topology
3RL3A 2AHDA 4ZVZA 2BCDA 3C5WC 4J6OA 1FJMA 5JPFA 3E0JA 5C1VA 4KBPA 3IVDA 1TCOA 3H67A 3QFMA 3P71C 3QG5C 1V73A 3LL8A 4IYPC 4H2GA 3K7WC 1QFCA 2ZBMA 2HYOA 2WDDA 1OI8A 1HO5A 4O43A 3THNA 4UT3B 2YVTA 3CK2A 4I5NC 4ORBA 2R17A 1M63A 3DW8C 4WWLA 2QJCA 4XPNA 3H66A 4FBKA 4MOYA 2HY1A 4TUGA 2ZO9B 3H61A 4V0VA 3HVQA 3IB7A 1AUIA 3EGGA 5F3WA 4OR9A 3QFKA 2WDCA 3QFNA 1S3LA 4LU9A 2A22A 3ZU0A 5JPEA 3PSNA 1HP1A 1S70A 1XZWA 1U32A 4O24A 4H2FA 4ZX2A 5INBA 4TUIA 3RL5A 3T1IA 3E7AA 2GJUA 2XMOA 2QFPA 2O8GA 3ICFA 1WAO1 1S95A 2Q8UA 3RL4A 3IB8A 2P6BA 4MP0A 3EGHA 1IT6A 4B2OA 3H64A 3GVEA 4HD0A 3ZTVA 4UT3A 3K7VC 3N5UA 2BDXA 2Z06A 1UF3A 4NZVA 2Z1AA 4M0VA 1OIDA 1KBPA 2DFJA 2IE3C 1HPUA 3DSCA 3DSDA 2YEQA 1II7A 3FLOA 2WDEA 4V0WA 4LTYA 5IOHA 2NPPC 4ORAA 1Z2WA 1JK7A 1USHA 1MF8A 4IL1A 4UT2A 4KKZA 4H1SA 3QFOA 3V4YA 4H2BA 1G5BA 4YKEA 2IAEC 1OIEA 4FBWA 4JA9A 2NYMC 4F0ZA 4I5LC 3RQZA 4G9JA 1UTEA 3JYFA 3H68A 3AV0A 4Q7FA 1QHWA 2DXNA 2NYLC 3H62B 3D03A 4O4KA 1S8EA 4ORCA 2ZOAA 4DSYA 1SU1A 2HYPA 2KKNA 5DNYA 3H60A 3C9FA 4JA7A 4H2IA 3PSOA 1S3MA 2IE4C 2JOGA 4V0XA 4LACC 3THOB 2O8AA 2WDFA 3FGAC 2BQ8X 4FBQA 5HPEA 3E7BA 4MOVA 2DXLA 5JJTA 2NXFA 5GTUA 3H63A 4DT2A 1Z2XA 3IVEA 4UWQA 3H69A 5B8IA 2QFRA 3AUZA 1T70A 4FCXA 5J28A 4O5GA 1S3NA 1NNWA 4DHLA 5EQVA 3KBPA 1T71A 1W24A 1WARA 3TGHA 4H1YP 1XM7A 2USHA 2Z72A 2CV9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RL3 A;  2AHD A;  4ZVZ A;  2BCD A;  3C5W C;  4J6O A;  1FJM A;  5JPF A;  5C1V A;  4KBP A;  3IVD A;  1TCO A;  3H67 A;  3QFM A;  3P71 C;  3QG5 C;  1V73 A;  3LL8 A;  4IYP C;  4H2G A;  3K7W C;  1QFC A;  2ZBM A;  2HYO A;  2WDD A;  1OI8 A;  1HO5 A;  4O43 A;  3THN A;  4UT3 B;  2YVT A;  3CK2 A;  4I5N C;  4ORB A;  2R17 A;  1M63 A;  3DW8 C;  4WWL A;  2QJC A;  4XPN A;  3H66 A;  4FBK A;  4MOY A;  2HY1 A;  4TUG A;  3H61 A;  4V0V A;  3HVQ A;  3IB7 A;  1AUI A;  3EGG A;  5F3W A;  4OR9 A;  3QFK A;  2WDC A;  3QFN A;  1S3L A;  4LU9 A;  2A22 A;  3ZU0 A;  5JPE A;  3PSN A;  1HP1 A;  1S70 A;  1XZW A;  1U32 A;  4O24 A;  4H2F A;  4ZX2 A;  5INB A;  4TUI A;  3RL5 A;  3T1I A;  3E7A A;  2GJU A;  2XMO A;  2QFP A;  2O8G A;  3ICF A;  1WAO 1;  1S95 A;  2Q8U A;  3RL4 A;  3IB8 A;  2P6B A;  4MP0 A;  3EGH A;  1IT6 A;  4B2O A;  3H64 A;  3GVE A;  4HD0 A;  3ZTV A;  4UT3 A;  3K7V C;  3N5U A;  2BDX A;  2Z06 A;  1UF3 A;  4NZV A;  2Z1A A;  4M0V A;  1OID A;  1KBP A;  2DFJ A;  2IE3 C;  1HPU A;  3DSC A;  3DSD A;  1II7 A;  4V0W A;  2WDE A;  4LTY A;  5IOH A;  2NPP C;  4ORA A;  1Z2W A;  1JK7 A;  1USH A;  1MF8 A;  4IL1 A;  4UT2 A;  4KKZ A;  4H1S A;  3QFO A;  3V4Y A;  4H2B A;  1G5B A;  4YKE A;  2IAE C;  1OIE A;  4FBW A;  4JA9 A;  2NYM C;  4F0Z A;  4I5L C;  3RQZ A;  4G9J A;  1UTE A;  3JYF A;  3H68 A;  3AV0 A;  4Q7F A;  1QHW A;  2NYL C;  3H62 B;  4O4K A;  1S8E A;  4ORC A;  5DNY A;  4DSY A;  1SU1 A;  2HYP A;  2KKN A;  3H60 A;  3C9F A;  4JA7 A;  4H2I A;  3PSO A;  1S3M A;  2IE4 C;  2JOG A;  4V0X A;  4LAC C;  3THO B;  2O8A A;  2WDF A;  3FGA C;  2BQ8 X;  4FBQ A;  5HPE A;  3E7B A;  4MOV A;  5JJT A;  2NXF A;  5GTU A;  3H63 A;  4DT2 A;  1Z2X A;  3IVE A;  4UWQ A;  3H69 A;  5B8I A;  2QFR A;  3AUZ A;  1T70 A;  4FCX A;  5J28 A;  4O5G A;  1S3N A;  1NNW A;  4DHL A;  5EQV A;  3KBP A;  1T71 A;  1W24 A;  1WAR A;  3TGH A;  4H1Y P;  1XM7 A;  2USH A;  2Z72 A;  2CV9 A; 
#chains in the Genus database with same CATH topology
 3RL3 A;  2AHD A;  4ZVZ A;  2BCD A;  3C5W C;  4J6O A;  1FJM A;  5JPF A;  3E0J A;  5C1V A;  4KBP A;  3IVD A;  1TCO A;  3H67 A;  3QFM A;  3P71 C;  3QG5 C;  1V73 A;  3LL8 A;  4IYP C;  4H2G A;  3K7W C;  1QFC A;  2ZBM A;  2HYO A;  2WDD A;  1OI8 A;  1HO5 A;  4O43 A;  3THN A;  4UT3 B;  2YVT A;  3CK2 A;  4I5N C;  4ORB A;  2R17 A;  1M63 A;  3DW8 C;  4WWL A;  2QJC A;  4XPN A;  3H66 A;  4FBK A;  4MOY A;  2HY1 A;  4TUG A;  2ZO9 B;  3H61 A;  4V0V A;  3HVQ A;  3IB7 A;  1AUI A;  3EGG A;  5F3W A;  4OR9 A;  3QFK A;  2WDC A;  3QFN A;  1S3L A;  4LU9 A;  2A22 A;  3ZU0 A;  5JPE A;  3PSN A;  1HP1 A;  1S70 A;  1XZW A;  1U32 A;  4O24 A;  4H2F A;  4ZX2 A;  5INB A;  4TUI A;  3RL5 A;  3T1I A;  3E7A A;  2GJU A;  2XMO A;  2QFP A;  2O8G A;  3ICF A;  1WAO 1;  1S95 A;  2Q8U A;  3RL4 A;  3IB8 A;  2P6B A;  4MP0 A;  3EGH A;  1IT6 A;  4B2O A;  3H64 A;  3GVE A;  4HD0 A;  3ZTV A;  4UT3 A;  3K7V C;  3N5U A;  2BDX A;  2Z06 A;  1UF3 A;  4NZV A;  2Z1A A;  4M0V A;  1OID A;  1KBP A;  2DFJ A;  2IE3 C;  1HPU A;  3DSC A;  3DSD A;  2YEQ A;  1II7 A;  3FLO A;  2WDE A;  4V0W A;  4LTY A;  5IOH A;  2NPP C;  4ORA A;  1Z2W A;  1JK7 A;  1USH A;  1MF8 A;  4IL1 A;  4UT2 A;  4KKZ A;  4H1S A;  3QFO A;  3V4Y A;  4H2B A;  1G5B A;  4YKE A;  2IAE C;  1OIE A;  4FBW A;  4JA9 A;  2NYM C;  4F0Z A;  4I5L C;  3RQZ A;  4G9J A;  1UTE A;  3JYF A;  3H68 A;  3AV0 A;  4Q7F A;  1QHW A;  2DXN A;  2NYL C;  3H62 B;  3D03 A;  4O4K A;  1S8E A;  4ORC A;  2ZOA A;  4DSY A;  1SU1 A;  2HYP A;  2KKN A;  5DNY A;  3H60 A;  3C9F A;  4JA7 A;  4H2I A;  3PSO A;  1S3M A;  2IE4 C;  2JOG A;  4V0X A;  4LAC C;  3THO B;  2O8A A;  2WDF A;  3FGA C;  2BQ8 X;  4FBQ A;  5HPE A;  3E7B A;  4MOV A;  2DXL A;  5JJT A;  2NXF A;  5GTU A;  3H63 A;  4DT2 A;  1Z2X A;  3IVE A;  4UWQ A;  3H69 A;  5B8I A;  2QFR A;  3AUZ A;  1T70 A;  4FCX A;  5J28 A;  4O5G A;  1S3N A;  1NNW A;  4DHL A;  5EQV A;  3KBP A;  1T71 A;  1W24 A;  1WAR A;  3TGH A;  4H1Y P;  1XM7 A;  2USH A;  2Z72 A;  2CV9 A; 
#chains in the Genus database with same CATH homology
 3RL3 A;  2AHD A;  4ZVZ A;  2BCD A;  3C5W C;  4J6O A;  1FJM A;  5JPF A;  3E0J A;  5C1V A;  4KBP A;  3IVD A;  1TCO A;  3H67 A;  3QFM A;  3P71 C;  3QG5 C;  1V73 A;  3LL8 A;  4IYP C;  4H2G A;  3K7W C;  1QFC A;  2ZBM A;  2HYO A;  2WDD A;  1OI8 A;  1HO5 A;  4O43 A;  3THN A;  4UT3 B;  2YVT A;  3CK2 A;  4I5N C;  4ORB A;  2R17 A;  1M63 A;  3DW8 C;  4WWL A;  2QJC A;  4XPN A;  3H66 A;  4FBK A;  4MOY A;  2HY1 A;  4TUG A;  2ZO9 B;  3H61 A;  4V0V A;  3HVQ A;  3IB7 A;  1AUI A;  3EGG A;  5F3W A;  4OR9 A;  3QFK A;  2WDC A;  3QFN A;  1S3L A;  4LU9 A;  2A22 A;  3ZU0 A;  5JPE A;  3PSN A;  1HP1 A;  1S70 A;  1XZW A;  1U32 A;  4O24 A;  4H2F A;  4ZX2 A;  5INB A;  4TUI A;  3RL5 A;  3T1I A;  3E7A A;  2GJU A;  2XMO A;  2QFP A;  2O8G A;  3ICF A;  1WAO 1;  1S95 A;  2Q8U A;  3RL4 A;  3IB8 A;  2P6B A;  4MP0 A;  3EGH A;  1IT6 A;  4B2O A;  3H64 A;  3GVE A;  4HD0 A;  3ZTV A;  4UT3 A;  3K7V C;  3N5U A;  2BDX A;  2Z06 A;  1UF3 A;  4NZV A;  2Z1A A;  4M0V A;  1OID A;  1KBP A;  2DFJ A;  2IE3 C;  1HPU A;  3DSC A;  3DSD A;  2YEQ A;  1II7 A;  3FLO A;  2WDE A;  4V0W A;  4LTY A;  5IOH A;  2NPP C;  4ORA A;  1Z2W A;  1JK7 A;  1USH A;  1MF8 A;  4IL1 A;  4UT2 A;  4KKZ A;  4H1S A;  3QFO A;  3V4Y A;  4H2B A;  1G5B A;  4YKE A;  2IAE C;  1OIE A;  4FBW A;  4JA9 A;  2NYM C;  4F0Z A;  4I5L C;  3RQZ A;  4G9J A;  1UTE A;  3JYF A;  3H68 A;  3AV0 A;  4Q7F A;  1QHW A;  2DXN A;  2NYL C;  3H62 B;  3D03 A;  4O4K A;  1S8E A;  4ORC A;  2ZOA A;  4DSY A;  1SU1 A;  2HYP A;  2KKN A;  5DNY A;  3H60 A;  3C9F A;  4JA7 A;  4H2I A;  3PSO A;  1S3M A;  2IE4 C;  2JOG A;  4V0X A;  4LAC C;  3THO B;  2O8A A;  2WDF A;  3FGA C;  2BQ8 X;  4FBQ A;  5HPE A;  3E7B A;  4MOV A;  2DXL A;  5JJT A;  2NXF A;  5GTU A;  3H63 A;  4DT2 A;  1Z2X A;  3IVE A;  4UWQ A;  3H69 A;  5B8I A;  2QFR A;  3AUZ A;  1T70 A;  4FCX A;  5J28 A;  4O5G A;  1S3N A;  1NNW A;  4DHL A;  5EQV A;  3KBP A;  1T71 A;  1W24 A;  1WAR A;  3TGH A;  4H1Y P;  1XM7 A;  2USH A;  2Z72 A;  2CV9 A; 
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