1K83L

Crystal structure of yeast rna polymerase ii complexed with the inhibitor alpha amanitin
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
45
structure length
45
Chain Sequence
TLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Transcription: Alpha-Amanitin-RNA Polymerase II Cocrystal at 2.8 A Resolution.
pubmed doi rcsb
molecule tags Transcription/toxin
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 1
structure length 45
sequence length 45
ec nomenclature
pdb deposition date 2001-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 1k83L00
2R7ZL 3RZDL 5FLML 3H0GL 5C44L 4AYBP 3H3VM 3FKIL 1TWFL 5IYCL 2NVTL 5C3EL 3GTGL 3HOXL 3S2HL 3S14L 4Y7NL 1SFOL 3S2DL 2E2HL 2JA7L 4A3DL 1TWCL 2JA8L 4A3FL 3GTKL 3S17L 5M3FL 3S16L 4A3KL 1I3QL 3M3YL 5IYDL 4A3JL 3GTML 4A3EL 2NVQL 5M5WL 4A3BL 2R93L 5M3ML 3S15L 3RZOL 1Y1WL 3HOWL 2WB1P 4A3ML 5IP9L 2PMZP 4BY1L 4QIWP 4BY7L 3CQZL 2VUML 4C2M1 1Y1VL 4X6AL 5IYBL 3S1QL 1WCML 1TWHL 4A93L 3GTQL 2WAQP 3GTOL 3GTJL 2JA6L 1I50L 3HKZP 1K83L 2YU9L 2B63L 4A3IL 4Y52L 4C3HL 3GTPL 2E2JL 3HOUL 5M5XL 5M5YL 3I4ML 4A3GL 1TWGL 1R9TL 3PO2L 2R92L 5FJ8L 2JA5L 3HOVL 5IP7L 2NVYL 3GTLL 3S1NL 3S1ML 3I4NL 4C3IL 3S1RL 1TWAL 4A3CL 3HOYL 3M4OL 3K7AL 4A3LL 5C4JL 4BBRL 2Y0SP 2NVXL 5C4XL 4C3JL 1I6HL 2E2IL 4BXXL 4BBSL 3HOZL 3PO3L
chains in the Genus database with same CATH superfamily
2LCQA 3RZDL 3HJWB 4B8CD 5GADc 3MSUA 1TWFL 3LNLA 3GTGL 1T9OA 3S2DL 1SFOL 2E2HL 2VL6A 2BE5D 3PKIA 3GTKL 2AUSB 2JI1A 4A3KL 2ERSA 5GAGc 4AI3A 5IYDL 4JADA 4ZN1B 5M5WL 3RZOL 3HOWL 2APOB 4BY7L 2A68D 5EIOC 1VZIA 1SMUA 1Z92B 3KYUA 3S1QL 4LHLA 1BFYA 2EY4E 1PZXA 2WAQP 2B63L 3LWVB 2C6BA 4C3HL 1NXEA 4ME3A 3GTPL 4UY81 1QCVA 5AI3A 3PIP1 4ZN3B 5M5XL 5M5YL 1FHHA 1TWGL 1R9TL 2AQCA 1SMMA 3LPEB 3PIO1 3HOVL 2PVXA 1IW7D 2DSXA 3I4NL 1IU6A 1CADA 3QVDA 2QL0A 1PFUA 3HOYL 3QQCE 5C4JL 1OWCA 4E6YA 2Z3RB 3PL5A 1B13A 2AYJA 5DM71 5FLML 3H0GL 5H1Sc 1R0IA 3HJYB 4XXBB 3A44A 2XJVA 4YWMA 3LWQB 3S14L 1RYTA 2A6HD 2L0ZA 4Y7NL 2JA7L 5K2ME 2M6PA 4A3FL 5M3FL 1RWDA 4GS7D 4A3JL 5MF6A 4A3EL 4A3BL 2R93L 5JVG1 3H97A 1QYBA 2Z3QB 1BE7A 3PZAA 1VZGA 3B0AB 5IP9L 2PMZP 4BY1L 1T9PA 4POFA 4C2M1 4AI2A 4AHZA 4YWLA 1T9QA 5AI2A 2O5JD 3GTOL 1I50L 2YU9L 4A3IL 1RYQA 3H9CA 1SMWA 2PVEA 2J9UB 3FDJA 4JAEA 2B5ID 1RDVA 4A3GL 2A6ED 1BQ9A 2JA5L 3KYVA 3SS2A 1H7VA 3P8BA 2NVYL 3S1NL 3MPSA 3RZ6A 2XJSA 2KKDA 2XJRA 1NXGA 1R0HA 5AN9H 4A3CL 1OWBA 3KYWA 5C4XL 4AR3A 1I6HL 4RXNA 1QQTA 4BXXL 4BBSL 3WWLA 1ODHA 3PO3L 3P2AA 1R0GA 2R7ZL 3WWNB 5C44L 4AYBP 3H3VM 3H99A 4AR6A 2H12A 1ZRPA 3S2HL 1YK5A 2KN9A 4U671 1TWCL 4XGHA 2JA8L 5DM61 3S16L 1IRNA 2HVYC 2NVQL 4V196 3LWRB 3H9BA 1Y1WL 2M4VA 2WB1P 2XJQA 4A3ML 4TPUA 4QIWP 4AI1A 1VZHA 3VPBE 4AHXA 5JVH1 5GAHc 2PSMC 5RXNA 6RXNA 1WCML 1TWHL 4A93L 3KYXA 3GTJL 2JA6L 2CKCA 3HKZP 1K83L 3PWFA 1S2ZA 3PKJA 3RYGA 3ZG6A 1LKOA 3HOUL 2HR5A 4POGA 2CR8A 2RFKB 1LKMA 1S24A 5IP7L 1IROA 3K35A 4C3IL 1DX8A 1TWAL 3HAXC 2C6AA 5MGNA 1PFVA 1F4LA 2RDVA 2Y0SP 4JAFA 2NVXL 1LTLA 1R0JA 1B2OA 4C3JL 1PFWA 4AR4A 4AHWA 1BRFA 4LHNA 1PFYA 1YUZA 1P7PA 1RB9A 3FKIL 2V0EA 5EINC 5IYCL 2XJUA 2NVTL 5C3EL 1NNQA 3HOXL 3NFPI 1DVBA 1E8JA 4JAGA 5MFZA 4A3DL 1CAAA 3KYYA 4AI0A 3S17L 3RZTA 2JI3A 2MS3A 2M4YA 1I3QL 4K9FA 7RXNA 4G6BA 3M3YL 2M6OA 3LWPB 3GTML 1C09A 4AHYA 5M3ML 3S15L 3IU3I 1YK4A 3CQZL 2GMGA 1IU5A 2VUML 3LWOB 1LKPA 1Y1VL 4X6AL 5IYBL 2V0FA 3MQKB 3GTQL 1B71A 2PPTA 4Y52L 1BQ8A 2JI2A 2E2JL 1FHMA 1YV1A 3JR7A 1B2JA 2XJTA 3I4ML 5IY0A 2A69D 3PO2L 1WJVA 2R92L 5FJ8L 4TVMA 1R0FA 4WFN1 8RXNA 3GTLL 3S1ML 3S1RL 2K2DA 1YUXA 2CKAA 3M4OL 5MLC3 3J7Z1 3K7AL 2PYAA 1VCXA 2V3BB 4BBRL 4A3LL 2NYDA 2ERJA 1S30A 4AR5A 5MFPA 3J7Y1 2XJPA 5GAEc 3B08B 2E2IL 2ZIXA 3HOZL 1RDGA 1JYBA
chains in the Genus database with same CATH topology
2R7ZL 3RZDL 5FLML 3H0GL 5C44L 4AYBP 3H3VM 3FKIL 1TWFL 5IYCL 2NVTL 5C3EL 3GTGL 3HOXL 3S2HL 3S14L 4Y7NL 1SFOL 3S2DL 2E2HL 2JA7L 4A3DL 1TWCL 2JA8L 4A3FL 3GTKL 3S17L 5M3FL 3S16L 4A3KL 1I3QL 3M3YL 5IYDL 4A3JL 3GTML 4A3EL 2NVQL 5M5WL 4A3BL 2R93L 5M3ML 3S15L 3RZOL 1Y1WL 3HOWL 2WB1P 4A3ML 5IP9L 2PMZP 4BY1L 4QIWP 4BY7L 3CQZL 2VUML 4C2M1 1Y1VL 4X6AL 5IYBL 3S1QL 1WCML 1TWHL 4A93L 3GTQL 2WAQP 3GTOL 3GTJL 2JA6L 1I50L 3HKZP 1K83L 2YU9L 2B63L 4A3IL 4Y52L 4C3HL 3GTPL 2E2JL 3HOUL 5M5XL 5M5YL 3I4ML 4A3GL 1TWGL 1R9TL 3PO2L 2R92L 5FJ8L 2JA5L 3HOVL 5IP7L 2NVYL 3GTLL 3S1NL 3S1ML 3I4NL 4C3IL 3S1RL 1TWAL 4A3CL 3HOYL 3M4OL 3K7AL 4A3LL 5C4JL 4BBRL 2Y0SP 2NVXL 5C4XL 4C3JL 1I6HL 2E2IL 4BXXL 4BBSL 3HOZL 3PO3L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R7Z L;  3RZD L;  5FLM L;  3H0G L;  5C44 L;  4AYB P;  3H3V M;  3FKI L;  1TWF L;  5IYC L;  2NVT L;  5C3E L;  3GTG L;  3HOX L;  3S2H L;  3S14 L;  4Y7N L;  1SFO L;  3S2D L;  2E2H L;  2JA7 L;  4A3D L;  1TWC L;  2JA8 L;  4A3F L;  3GTK L;  3S17 L;  5M3F L;  3S16 L;  4A3K L;  1I3Q L;  3M3Y L;  5IYD L;  4A3J L;  3GTM L;  4A3E L;  2NVQ L;  5M5W L;  4A3B L;  2R93 L;  5M3M L;  3S15 L;  3RZO L;  1Y1W L;  3HOW L;  2WB1 P;  4A3M L;  5IP9 L;  2PMZ P;  4BY1 L;  4QIW P;  4BY7 L;  3CQZ L;  2VUM L;  4C2M 1;  1Y1V L;  4X6A L;  5IYB L;  3S1Q L;  1WCM L;  1TWH L;  4A93 L;  3GTQ L;  2WAQ P;  3GTO L;  3GTJ L;  2JA6 L;  1I50 L;  3HKZ P;  1K83 L;  2YU9 L;  2B63 L;  4A3I L;  4Y52 L;  4C3H L;  3GTP L;  2E2J L;  3HOU L;  5M5X L;  5M5Y L;  3I4M L;  4A3G L;  1TWG L;  1R9T L;  3PO2 L;  2R92 L;  5FJ8 L;  2JA5 L;  3HOV L;  5IP7 L;  2NVY L;  3GTL L;  3S1N L;  3S1M L;  3I4N L;  4C3I L;  3S1R L;  1TWA L;  4A3C L;  3HOY L;  3M4O L;  3K7A L;  4A3L L;  5C4J L;  4BBR L;  2Y0S P;  2NVX L;  5C4X L;  4C3J L;  1I6H L;  2E2I L;  4BXX L;  4BBS L;  3HOZ L;  3PO3 L; 
#chains in the Genus database with same CATH topology
 2LCQ A;  3RZD L;  3HJW B;  4B8C D;  5GAD c;  3MSU A;  1TWF L;  3LNL A;  3GTG L;  1T9O A;  3S2D L;  1SFO L;  2E2H L;  2VL6 A;  2BE5 D;  3PKI A;  3GTK L;  2AUS B;  2JI1 A;  4A3K L;  2ERS A;  5GAG c;  4AI3 A;  5IYD L;  4JAD A;  4ZN1 B;  5M5W L;  3RZO L;  3HOW L;  2APO B;  4BY7 L;  2A68 D;  5EIO C;  1VZI A;  1SMU A;  1Z92 B;  3KYU A;  3S1Q L;  4LHL A;  1BFY A;  2EY4 E;  1PZX A;  2WAQ P;  2B63 L;  3LWV B;  2C6B A;  4C3H L;  1NXE A;  4ME3 A;  3GTP L;  4UY8 1;  1QCV A;  5AI3 A;  3PIP 1;  4ZN3 B;  5M5X L;  5M5Y L;  1FHH A;  1TWG L;  1R9T L;  2AQC A;  1SMM A;  3LPE B;  3PIO 1;  3HOV L;  2PVX A;  1IW7 D;  2DSX A;  3I4N L;  1IU6 A;  1CAD A;  3QVD A;  2QL0 A;  1PFU A;  3HOY L;  3QQC E;  5C4J L;  1OWC A;  4E6Y A;  2Z3R B;  3PL5 A;  1B13 A;  2AYJ A;  5DM7 1;  5FLM L;  3H0G L;  5H1S c;  1R0I A;  3HJY B;  4XXB B;  3A44 A;  2XJV A;  4YWM A;  3LWQ B;  3S14 L;  1RYT A;  2A6H D;  2L0Z A;  4Y7N L;  2JA7 L;  5K2M E;  2M6P A;  4A3F L;  5M3F L;  1RWD A;  4GS7 D;  4A3J L;  5MF6 A;  4A3E L;  4A3B L;  2R93 L;  5JVG 1;  3H97 A;  1QYB A;  2Z3Q B;  1BE7 A;  3PZA A;  1VZG A;  3B0A B;  5IP9 L;  2PMZ P;  4BY1 L;  1T9P A;  4POF A;  4C2M 1;  4AI2 A;  4AHZ A;  4YWL A;  1T9Q A;  5AI2 A;  2O5J D;  3GTO L;  1I50 L;  2YU9 L;  4A3I L;  1RYQ A;  3H9C A;  1SMW A;  2PVE A;  2J9U B;  3FDJ A;  4JAE A;  2B5I D;  1RDV A;  4A3G L;  2A6E D;  1BQ9 A;  2JA5 L;  3KYV A;  3SS2 A;  1H7V A;  3P8B A;  2NVY L;  3S1N L;  3MPS A;  3RZ6 A;  2XJS A;  2KKD A;  2XJR A;  1NXG A;  1R0H A;  5AN9 H;  4A3C L;  1OWB A;  3KYW A;  5C4X L;  4AR3 A;  1I6H L;  4RXN A;  1QQT A;  4BXX L;  4BBS L;  3WWL A;  1ODH A;  3PO3 L;  3P2A A;  1R0G A;  2R7Z L;  3WWN B;  5C44 L;  4AYB P;  3H3V M;  3H99 A;  4AR6 A;  2H12 A;  1ZRP A;  3S2H L;  1YK5 A;  2KN9 A;  4U67 1;  1TWC L;  4XGH A;  2JA8 L;  5DM6 1;  3S16 L;  1IRN A;  2HVY C;  2NVQ L;  4V19 6;  3LWR B;  3H9B A;  1Y1W L;  2M4V A;  2WB1 P;  2XJQ A;  4A3M L;  4TPU A;  4QIW P;  4AI1 A;  1VZH A;  3VPB E;  4AHX A;  5JVH 1;  5GAH c;  2PSM C;  5RXN A;  6RXN A;  1WCM L;  1TWH L;  4A93 L;  3KYX A;  3GTJ L;  2JA6 L;  2CKC A;  3HKZ P;  1K83 L;  3PWF A;  1S2Z A;  3PKJ A;  3RYG A;  3ZG6 A;  1LKO A;  3HOU L;  2HR5 A;  4POG A;  2CR8 A;  2RFK B;  1LKM A;  1S24 A;  5IP7 L;  1IRO A;  3K35 A;  4C3I L;  1DX8 A;  1TWA L;  3HAX C;  2C6A A;  5MGN A;  1PFV A;  1F4L A;  2RDV A;  2Y0S P;  4JAF A;  2NVX L;  1LTL A;  1R0J A;  1B2O A;  4C3J L;  1PFW A;  4AR4 A;  4AHW A;  1BRF A;  4LHN A;  1PFY A;  1YUZ A;  1P7P A;  1RB9 A;  3FKI L;  2V0E A;  5EIN C;  5IYC L;  2XJU A;  2NVT L;  5C3E L;  1NNQ A;  3HOX L;  3NFP I;  1DVB A;  1E8J A;  4JAG A;  5MFZ A;  4A3D L;  1CAA A;  3KYY A;  4AI0 A;  3S17 L;  3RZT A;  2JI3 A;  2MS3 A;  2M4Y A;  1I3Q L;  4K9F A;  7RXN A;  4G6B A;  3M3Y L;  2M6O A;  3LWP B;  3GTM L;  1C09 A;  4AHY A;  5M3M L;  3S15 L;  3IU3 I;  1YK4 A;  3CQZ L;  2GMG A;  1IU5 A;  2VUM L;  3LWO B;  1LKP A;  1Y1V L;  4X6A L;  5IYB L;  2V0F A;  3MQK B;  3GTQ L;  1B71 A;  2PPT A;  4Y52 L;  1BQ8 A;  2JI2 A;  2E2J L;  1FHM A;  1YV1 A;  3JR7 A;  1B2J A;  2XJT A;  3I4M L;  5IY0 A;  2A69 D;  3PO2 L;  1WJV A;  2R92 L;  5FJ8 L;  4TVM A;  1R0F A;  4WFN 1;  8RXN A;  3GTL L;  3S1M L;  3S1R L;  2K2D A;  1YUX A;  2CKA A;  3M4O L;  5MLC 3;  3J7Z 1;  3K7A L;  2PYA A;  1VCX A;  2V3B B;  4BBR L;  4A3L L;  2NYD A;  2ERJ A;  1S30 A;  4AR5 A;  5MFP A;  3J7Y 1;  2XJP A;  5GAE c;  3B08 B;  2E2I L;  2ZIX A;  3HOZ L;  1RDG A;  1JYB A; 
#chains in the Genus database with same CATH homology
 2R7Z L;  3RZD L;  5FLM L;  3H0G L;  5C44 L;  4AYB P;  3H3V M;  3FKI L;  1TWF L;  5IYC L;  2NVT L;  5C3E L;  3GTG L;  3HOX L;  3S2H L;  3S14 L;  4Y7N L;  1SFO L;  3S2D L;  2E2H L;  2JA7 L;  4A3D L;  1TWC L;  2JA8 L;  4A3F L;  3GTK L;  3S17 L;  5M3F L;  3S16 L;  4A3K L;  1I3Q L;  3M3Y L;  5IYD L;  4A3J L;  3GTM L;  4A3E L;  2NVQ L;  5M5W L;  4A3B L;  2R93 L;  5M3M L;  3S15 L;  3RZO L;  1Y1W L;  3HOW L;  2WB1 P;  4A3M L;  5IP9 L;  2PMZ P;  4BY1 L;  4QIW P;  4BY7 L;  3CQZ L;  2VUM L;  4C2M 1;  1Y1V L;  4X6A L;  5IYB L;  3S1Q L;  1WCM L;  1TWH L;  4A93 L;  3GTQ L;  2WAQ P;  3GTO L;  3GTJ L;  2JA6 L;  1I50 L;  3HKZ P;  1K83 L;  2YU9 L;  2B63 L;  4A3I L;  4Y52 L;  4C3H L;  3GTP L;  2E2J L;  3HOU L;  5M5X L;  5M5Y L;  3I4M L;  4A3G L;  1TWG L;  1R9T L;  3PO2 L;  2R92 L;  5FJ8 L;  2JA5 L;  3HOV L;  5IP7 L;  2NVY L;  3GTL L;  3S1N L;  3S1M L;  3I4N L;  4C3I L;  3S1R L;  1TWA L;  4A3C L;  3HOY L;  3M4O L;  3K7A L;  4A3L L;  5C4J L;  4BBR L;  2Y0S P;  2NVX L;  5C4X L;  4C3J L;  1I6H L;  2E2I L;  4BXX L;  4BBS L;  3HOZ L;  3PO3 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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