1OIEA

5'-nucleotidase (e. coli) with an engineered disulfide bridge (s228c, p513c)
Total Genus 171
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
171
sequence length
525
structure length
519
Chain Sequence
YEQDKTYKITVLHTNDHHGHFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLLSGGDINTGVPESDLQDAEPDFRGMNLVGYDAMAIGNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWALFKRQDLKIAVIGLTTDDTAKIGNPEYFTDIEFRKPADEAKLVIQELQQTEKPDIIIAATHMGHYDNGEHGCNAPGDVEMARALPAGSLAMIVGGHSQDPVCMAAENKKQVDYVPGTPCKPDQQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVSERVLYTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQTNMGRLILAAQMDRTGADFAVMSGGGIRDSIEAGDISYKNVLKVQPFGNVVVYADMTGKEVIDYLTAVAQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPAKTYRMATLNFNATGGDGYPRLDNKCGYVNTGFIDAEVLKAYIQKSSPLDVSVYEPKGEVSWQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Trapping a 96 Degree Domain Rotation in Two Distinct Conformations by Engineered Disulfide Bridges
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords PROTEIN USHA
total genus 171
structure length 519
sequence length 525
ec nomenclature ec 3.1.3.5: 5'-nucleotidase.
pdb deposition date 2003-06-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF02872 5_nucleotid_C 5'-nucleotidase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 1oieA01
3.90.780.10 Alpha Beta Alpha-Beta Complex 5'-nucleotidase; domain 2 5'-Nucleotidase, C-terminal domain 1oieA02
4IYPC 1NNWA 3C5WC 2Z1AA 3KBPA 4H2GA 2NYLC 2BDXA 3HVQA 2BCDA 4V0XA 1FJMA 2NXFA 4I5LC 2AHDA 3FGAC 4TUGA 4ORAA 4WWLA 4NZVA 1V73A 4KBPA 3JYFA 3QG5C 3QFNA 1UTEA 2USHA 3H63A 1HP1A 3PSNA 1II7A 4F0ZA 4Q7FA 2QFRA 3H64A 4FCXA 3H68A 3IVDA 1MF8A 1QFCA 2NYMC 3RL3A 4V0VA 1S3NA 2WDCA 2XMOA 4UWQA 1W24A 4FBKA 3T1IA 2A22A 3E7AA 1AUIA 1OIDA 2KKNA 4O4KA 4LU9A 5DNYA 4YKEA 5F3WA 4H1YP 4JA7A 4O5GA 4UT3B 4OR9A 1SU1A 4LTYA 4B2OA 2DFJA 4H2BA 2HYPA 3H61A 3THNA 4ZVZA 4MP0A 3DSDA 4ORCA 3V4YA 2Q8UA 4UT2A 4ORBA 2Z06A 2BQ8X 2WDEA 4M0VA 2QFPA 2QJCA 3CK2A 3K7VC 4KKZA 4MOVA 5HPEA 1M63A 1T70A 3H66A 4DSYA 1S8EA 1OI8A 4G9JA 1HPUA 2P6BA 4HD0A 2HYOA 5C1VA 1QHWA 4JA9A 1U32A 1KBPA 3TGHA 1S3MA 3QFOA 3THOB 1XZWA 1Z2WA 2WDFA 3N5UA 4FBWA 4ZX2A 5INBA 1OIEA 2JOGA 1TCOA 1G5BA 1UF3A 3DW8C 1S3LA 3EGHA 2YVTA 3RQZA 3QFKA 4DT2A 4V0WA 1T71A 3PSOA 2ZBMA 4O24A 1JK7A 3RL5A 4DHLA 4O43A 3ZTVA 4FBQA 3DSCA 3C9FA 1XM7A 2GJUA 1USHA 3IB7A 1S70A 4UT3A 3AUZA 2NPPC 3H60A 3H62B 5EQVA 3GVEA 2IE3C 3LL8A 4I5NC 1Z2XA 4MOYA 1WARA 3QFMA 2WDDA 3ICFA 3ZU0A 1IT6A 5JPFA 2IE4C 2R17A 3EGGA 4H2FA 4LACC 3IB8A 2O8GA 4H1SA 3RL4A 2IAEC 4TUIA 2Z72A 5J28A 3AV0A 3P71C 2CV9A 5GTUA 3K7WC 5JJTA 1HO5A 4IL1A 5JPEA 3H67A 4H2IA 3H69A 5B8IA 5IOHA 4XPNA 3IVEA 4J6OA 3E7BA 2HY1A 1S95A 2O8AA 1WAO1
chains in the Genus database with same CATH superfamily
4IYPC 1NNWA 3C5WC 2Z1AA 3KBPA 4H2GA 2NYLC 2BDXA 3HVQA 2BCDA 4V0XA 1FJMA 2NXFA 4I5LC 2AHDA 3FGAC 4TUGA 4ORAA 4WWLA 4NZVA 1V73A 4KBPA 3JYFA 3QG5C 3QFNA 1UTEA 2USHA 3H63A 1HP1A 3PSNA 1II7A 4F0ZA 4Q7FA 2QFRA 3H64A 3FLOA 4FCXA 3H68A 3IVDA 1MF8A 1QFCA 2NYMC 3RL3A 4V0VA 1S3NA 2WDCA 2XMOA 4UWQA 1W24A 4FBKA 3T1IA 2A22A 3E7AA 2ZO9B 1AUIA 1OIDA 2KKNA 4O4KA 4LU9A 5DNYA 4YKEA 5F3WA 4H1YP 4JA7A 4O5GA 4UT3B 4OR9A 1SU1A 4LTYA 4B2OA 2DFJA 3D03A 4H2BA 2HYPA 3H61A 3THNA 4ZVZA 4MP0A 3DSDA 4ORCA 3V4YA 2Q8UA 4UT2A 4ORBA 2Z06A 2BQ8X 2WDEA 4M0VA 2QFPA 2QJCA 3CK2A 3K7VC 4KKZA 4MOVA 5HPEA 1M63A 1T70A 3H66A 4DSYA 1S8EA 1OI8A 4G9JA 1HPUA 2DXLA 2P6BA 4HD0A 2HYOA 5C1VA 1QHWA 4JA9A 1U32A 1KBPA 3TGHA 1S3MA 3QFOA 3THOB 1XZWA 1Z2WA 2WDFA 3N5UA 2DXNA 4FBWA 4ZX2A 5INBA 1OIEA 2JOGA 1TCOA 1G5BA 1UF3A 3DW8C 1S3LA 3EGHA 2YVTA 3RQZA 3QFKA 4DT2A 4V0WA 1T71A 3PSOA 2ZBMA 4O24A 1JK7A 3RL5A 4DHLA 4O43A 3E0JA 4FBQA 3ZTVA 3DSCA 3C9FA 1XM7A 2GJUA 1USHA 3IB7A 1S70A 4UT3A 3AUZA 2NPPC 3H60A 3H62B 5EQVA 3GVEA 2IE3C 3LL8A 4I5NC 1Z2XA 4MOYA 1WARA 3QFMA 2WDDA 3ICFA 3ZU0A 1IT6A 5JPFA 2IE4C 2R17A 3EGGA 4H2FA 4LACC 3IB8A 2YEQA 2O8GA 4H1SA 3RL4A 2IAEC 4TUIA 2Z72A 5J28A 3AV0A 3P71C 2CV9A 5GTUA 3K7WC 5JJTA 1HO5A 4IL1A 5JPEA 3H67A 4H2IA 3H69A 5B8IA 5IOHA 4XPNA 3IVEA 4J6OA 3E7BA 2HY1A 2ZOAA 1S95A 2O8AA 1WAO1
chains in the Genus database with same CATH topology
4IYPC 1NNWA 3C5WC 2Z1AA 3KBPA 4H2GA 2NYLC 2BDXA 3HVQA 2BCDA 4V0XA 1FJMA 2NXFA 4I5LC 2AHDA 3FGAC 4TUGA 4ORAA 4WWLA 4NZVA 1V73A 4KBPA 3JYFA 3QG5C 3QFNA 1UTEA 2USHA 3H63A 1HP1A 3PSNA 1II7A 4F0ZA 4Q7FA 2QFRA 3H64A 3FLOA 4FCXA 3H68A 3IVDA 1MF8A 1QFCA 2NYMC 3RL3A 4V0VA 1S3NA 2WDCA 2XMOA 4UWQA 1W24A 4FBKA 3T1IA 2A22A 3E7AA 2ZO9B 1AUIA 1OIDA 2KKNA 4O4KA 4LU9A 5DNYA 4YKEA 5F3WA 4H1YP 4JA7A 4O5GA 4UT3B 4OR9A 1SU1A 4LTYA 4B2OA 2DFJA 3D03A 4H2BA 2HYPA 3H61A 3THNA 4ZVZA 4MP0A 3DSDA 4ORCA 3V4YA 2Q8UA 4UT2A 4ORBA 2Z06A 2BQ8X 2WDEA 4M0VA 2QFPA 2QJCA 3CK2A 3K7VC 4KKZA 4MOVA 5HPEA 1M63A 1T70A 3H66A 4DSYA 1S8EA 1OI8A 4G9JA 1HPUA 2DXLA 2P6BA 4HD0A 2HYOA 5C1VA 1QHWA 4JA9A 1U32A 1KBPA 3TGHA 1S3MA 3QFOA 3THOB 1XZWA 1Z2WA 2WDFA 3N5UA 2DXNA 4FBWA 4ZX2A 5INBA 1OIEA 2JOGA 1TCOA 1G5BA 1UF3A 3DW8C 1S3LA 3EGHA 2YVTA 3RQZA 3QFKA 4DT2A 4V0WA 1T71A 3PSOA 2ZBMA 4O24A 1JK7A 3RL5A 4DHLA 4O43A 3E0JA 4FBQA 3ZTVA 3DSCA 3C9FA 1XM7A 2GJUA 1USHA 3IB7A 1S70A 4UT3A 3AUZA 2NPPC 3H60A 3H62B 5EQVA 3GVEA 2IE3C 3LL8A 4I5NC 1Z2XA 4MOYA 1WARA 3QFMA 2WDDA 3ICFA 3ZU0A 1IT6A 5JPFA 2IE4C 2R17A 3EGGA 4H2FA 4LACC 3IB8A 2YEQA 2O8GA 4H1SA 3RL4A 2IAEC 4TUIA 2Z72A 5J28A 3AV0A 3P71C 2CV9A 5GTUA 3K7WC 5JJTA 1HO5A 4IL1A 5JPEA 3H67A 4H2IA 3H69A 5B8IA 5IOHA 4XPNA 3IVEA 4J6OA 3E7BA 2HY1A 2ZOAA 1S95A 2O8AA 1WAO1
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IYP C;  1NNW A;  3C5W C;  2Z1A A;  3KBP A;  4H2G A;  2NYL C;  2BDX A;  3HVQ A;  2BCD A;  4V0X A;  1FJM A;  2NXF A;  4I5L C;  2AHD A;  3FGA C;  4TUG A;  4ORA A;  4WWL A;  4NZV A;  1V73 A;  4KBP A;  3JYF A;  3QG5 C;  3QFN A;  1UTE A;  2USH A;  3H63 A;  1HP1 A;  3PSN A;  1II7 A;  4F0Z A;  4Q7F A;  2QFR A;  3H64 A;  4FCX A;  3H68 A;  3IVD A;  1MF8 A;  1QFC A;  2NYM C;  3RL3 A;  4V0V A;  1S3N A;  2WDC A;  2XMO A;  4UWQ A;  1W24 A;  4FBK A;  3T1I A;  2A22 A;  3E7A A;  1AUI A;  1OID A;  2KKN A;  4O4K A;  4LU9 A;  5DNY A;  4YKE A;  5F3W A;  4H1Y P;  4JA7 A;  4O5G A;  4UT3 B;  4OR9 A;  1SU1 A;  4LTY A;  4B2O A;  2DFJ A;  4H2B A;  2HYP A;  3H61 A;  3THN A;  4ZVZ A;  4MP0 A;  3DSD A;  4ORC A;  3V4Y A;  2Q8U A;  4UT2 A;  4ORB A;  2Z06 A;  2BQ8 X;  2WDE A;  4M0V A;  2QFP A;  2QJC A;  3CK2 A;  3K7V C;  4KKZ A;  4MOV A;  5HPE A;  1M63 A;  1T70 A;  3H66 A;  4DSY A;  1S8E A;  1OI8 A;  4G9J A;  1HPU A;  2P6B A;  4HD0 A;  2HYO A;  5C1V A;  1QHW A;  4JA9 A;  1U32 A;  1KBP A;  3TGH A;  1S3M A;  3QFO A;  3THO B;  1XZW A;  1Z2W A;  2WDF A;  3N5U A;  4FBW A;  4ZX2 A;  5INB A;  1OIE A;  2JOG A;  1TCO A;  1G5B A;  1UF3 A;  3DW8 C;  1S3L A;  3EGH A;  2YVT A;  3RQZ A;  3QFK A;  4DT2 A;  4V0W A;  1T71 A;  3PSO A;  2ZBM A;  4O24 A;  1JK7 A;  3RL5 A;  4DHL A;  4O43 A;  3ZTV A;  4FBQ A;  3DSC A;  3C9F A;  1XM7 A;  2GJU A;  1USH A;  3IB7 A;  1S70 A;  4UT3 A;  3AUZ A;  2NPP C;  3H60 A;  3H62 B;  5EQV A;  3GVE A;  2IE3 C;  3LL8 A;  4I5N C;  1Z2X A;  4MOY A;  1WAR A;  3QFM A;  2WDD A;  3ICF A;  3ZU0 A;  1IT6 A;  5JPF A;  2IE4 C;  2R17 A;  3EGG A;  4H2F A;  4LAC C;  3IB8 A;  2O8G A;  4H1S A;  3RL4 A;  2IAE C;  4TUI A;  2Z72 A;  5J28 A;  3AV0 A;  3P71 C;  2CV9 A;  5GTU A;  3K7W C;  5JJT A;  1HO5 A;  4IL1 A;  5JPE A;  3H67 A;  4H2I A;  3H69 A;  5B8I A;  5IOH A;  4XPN A;  3IVE A;  4J6O A;  3E7B A;  2HY1 A;  1S95 A;  2O8A A;  1WAO 1; 
#chains in the Genus database with same CATH topology
 4IYP C;  1NNW A;  3C5W C;  2Z1A A;  3KBP A;  4H2G A;  2NYL C;  2BDX A;  3HVQ A;  2BCD A;  4V0X A;  1FJM A;  2NXF A;  4I5L C;  2AHD A;  3FGA C;  4TUG A;  4ORA A;  4WWL A;  4NZV A;  1V73 A;  4KBP A;  3JYF A;  3QG5 C;  3QFN A;  1UTE A;  2USH A;  3H63 A;  1HP1 A;  3PSN A;  1II7 A;  4F0Z A;  4Q7F A;  2QFR A;  3H64 A;  3FLO A;  4FCX A;  3H68 A;  3IVD A;  1MF8 A;  1QFC A;  2NYM C;  3RL3 A;  4V0V A;  1S3N A;  2WDC A;  2XMO A;  4UWQ A;  1W24 A;  4FBK A;  3T1I A;  2A22 A;  3E7A A;  2ZO9 B;  1AUI A;  1OID A;  2KKN A;  4O4K A;  4LU9 A;  5DNY A;  4YKE A;  5F3W A;  4H1Y P;  4JA7 A;  4O5G A;  4UT3 B;  4OR9 A;  1SU1 A;  4LTY A;  4B2O A;  2DFJ A;  3D03 A;  4H2B A;  2HYP A;  3H61 A;  3THN A;  4ZVZ A;  4MP0 A;  3DSD A;  4ORC A;  3V4Y A;  2Q8U A;  4UT2 A;  4ORB A;  2Z06 A;  2BQ8 X;  2WDE A;  4M0V A;  2QFP A;  2QJC A;  3CK2 A;  3K7V C;  4KKZ A;  4MOV A;  5HPE A;  1M63 A;  1T70 A;  3H66 A;  4DSY A;  1S8E A;  1OI8 A;  4G9J A;  1HPU A;  2DXL A;  2P6B A;  4HD0 A;  2HYO A;  5C1V A;  1QHW A;  4JA9 A;  1U32 A;  1KBP A;  3TGH A;  1S3M A;  3QFO A;  3THO B;  1XZW A;  1Z2W A;  2WDF A;  3N5U A;  2DXN A;  4FBW A;  4ZX2 A;  5INB A;  1OIE A;  2JOG A;  1TCO A;  1G5B A;  1UF3 A;  3DW8 C;  1S3L A;  3EGH A;  2YVT A;  3RQZ A;  3QFK A;  4DT2 A;  4V0W A;  1T71 A;  3PSO A;  2ZBM A;  4O24 A;  1JK7 A;  3RL5 A;  4DHL A;  4O43 A;  3E0J A;  4FBQ A;  3ZTV A;  3DSC A;  3C9F A;  1XM7 A;  2GJU A;  1USH A;  3IB7 A;  1S70 A;  4UT3 A;  3AUZ A;  2NPP C;  3H60 A;  3H62 B;  5EQV A;  3GVE A;  2IE3 C;  3LL8 A;  4I5N C;  1Z2X A;  4MOY A;  1WAR A;  3QFM A;  2WDD A;  3ICF A;  3ZU0 A;  1IT6 A;  5JPF A;  2IE4 C;  2R17 A;  3EGG A;  4H2F A;  4LAC C;  3IB8 A;  2YEQ A;  2O8G A;  4H1S A;  3RL4 A;  2IAE C;  4TUI A;  2Z72 A;  5J28 A;  3AV0 A;  3P71 C;  2CV9 A;  5GTU A;  3K7W C;  5JJT A;  1HO5 A;  4IL1 A;  5JPE A;  3H67 A;  4H2I A;  3H69 A;  5B8I A;  5IOH A;  4XPN A;  3IVE A;  4J6O A;  3E7B A;  2HY1 A;  2ZOA A;  1S95 A;  2O8A A;  1WAO 1; 
#chains in the Genus database with same CATH homology
 4IYP C;  1NNW A;  3C5W C;  2Z1A A;  3KBP A;  4H2G A;  2NYL C;  2BDX A;  3HVQ A;  2BCD A;  4V0X A;  1FJM A;  2NXF A;  4I5L C;  2AHD A;  3FGA C;  4TUG A;  4ORA A;  4WWL A;  4NZV A;  1V73 A;  4KBP A;  3JYF A;  3QG5 C;  3QFN A;  1UTE A;  2USH A;  3H63 A;  1HP1 A;  3PSN A;  1II7 A;  4F0Z A;  4Q7F A;  2QFR A;  3H64 A;  3FLO A;  4FCX A;  3H68 A;  3IVD A;  1MF8 A;  1QFC A;  2NYM C;  3RL3 A;  4V0V A;  1S3N A;  2WDC A;  2XMO A;  4UWQ A;  1W24 A;  4FBK A;  3T1I A;  2A22 A;  3E7A A;  2ZO9 B;  1AUI A;  1OID A;  2KKN A;  4O4K A;  4LU9 A;  5DNY A;  4YKE A;  5F3W A;  4H1Y P;  4JA7 A;  4O5G A;  4UT3 B;  4OR9 A;  1SU1 A;  4LTY A;  4B2O A;  2DFJ A;  3D03 A;  4H2B A;  2HYP A;  3H61 A;  3THN A;  4ZVZ A;  4MP0 A;  3DSD A;  4ORC A;  3V4Y A;  2Q8U A;  4UT2 A;  4ORB A;  2Z06 A;  2BQ8 X;  2WDE A;  4M0V A;  2QFP A;  2QJC A;  3CK2 A;  3K7V C;  4KKZ A;  4MOV A;  5HPE A;  1M63 A;  1T70 A;  3H66 A;  4DSY A;  1S8E A;  1OI8 A;  4G9J A;  1HPU A;  2DXL A;  2P6B A;  4HD0 A;  2HYO A;  5C1V A;  1QHW A;  4JA9 A;  1U32 A;  1KBP A;  3TGH A;  1S3M A;  3QFO A;  3THO B;  1XZW A;  1Z2W A;  2WDF A;  3N5U A;  2DXN A;  4FBW A;  4ZX2 A;  5INB A;  1OIE A;  2JOG A;  1TCO A;  1G5B A;  1UF3 A;  3DW8 C;  1S3L A;  3EGH A;  2YVT A;  3RQZ A;  3QFK A;  4DT2 A;  4V0W A;  1T71 A;  3PSO A;  2ZBM A;  4O24 A;  1JK7 A;  3RL5 A;  4DHL A;  4O43 A;  3E0J A;  4FBQ A;  3ZTV A;  3DSC A;  3C9F A;  1XM7 A;  2GJU A;  1USH A;  3IB7 A;  1S70 A;  4UT3 A;  3AUZ A;  2NPP C;  3H60 A;  3H62 B;  5EQV A;  3GVE A;  2IE3 C;  3LL8 A;  4I5N C;  1Z2X A;  4MOY A;  1WAR A;  3QFM A;  2WDD A;  3ICF A;  3ZU0 A;  1IT6 A;  5JPF A;  2IE4 C;  2R17 A;  3EGG A;  4H2F A;  4LAC C;  3IB8 A;  2YEQ A;  2O8G A;  4H1S A;  3RL4 A;  2IAE C;  4TUI A;  2Z72 A;  5J28 A;  3AV0 A;  3P71 C;  2CV9 A;  5GTU A;  3K7W C;  5JJT A;  1HO5 A;  4IL1 A;  5JPE A;  3H67 A;  4H2I A;  3H69 A;  5B8I A;  5IOH A;  4XPN A;  3IVE A;  4J6O A;  3E7B A;  2HY1 A;  2ZOA A;  1S95 A;  2O8A A;  1WAO 1; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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