1S70A

Complex between protein ser/thr phosphatase-1 (delta) and the myosin phosphatase targeting subunit 1 (mypt1)
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
309
structure length
309
Chain Sequence
HMADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of protein phosphatase 1 regulation
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Serine/threonine protein phosphatase PP1-beta (or delta) cat
total genus 101
structure length 309
sequence length 309
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2004-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 1s70A00
5DNYA 1U32A 3QFKA 4UT3A 3H69A 3K7WC 4MOYA 3IB8A 1TCOA 1SU1A 1OIEA 2Q8UA 3H60A 3QG5C 4I5NC 3E7AA 4DT2A 4H1YP 2O8AA 4V0WA 3ZTVA 1IT6A 2IE3C 2Z1AA 3CK2A 2JOGA 2AHDA 3IVDA 4ZVZA 3KBPA 2USHA 1M63A 4OR9A 1T71A 3LL8A 4UWQA 1KBPA 3AV0A 4V0VA 2A22A 4H2IA 2IAEC 1MF8A 4FBKA 3K7VC 2QFPA 3EGGA 3ICFA 4H2FA 3RL4A 2QFRA 3HVQA 1UF3A 1FJMA 4FBQA 4O5GA 4FCXA 4H2GA 4DSYA 4YKEA 1XZWA 2HY1A 3DW8C 3EGHA 5INBA 4NZVA 3PSOA 4I5LC 4J6OA 4IYPC 3QFNA 4UT2A 1G5BA 1NNWA 1OIDA 3IVEA 1HPUA 3H66A 4O43A 2NXFA 3IB7A 4ORCA 5J28A 2XMOA 3C5WC 4G9JA 4IL1A 4M0VA 4WWLA 4XPNA 4TUGA 4O24A 1S70A 2NYLC 2IE4C 3JYFA 1II7A 5GTUA 1UTEA 4MOVA 4H2BA 1V73A 4JA9A 3PSNA 4V0XA 1JK7A 4HD0A 3FGAC 2BDXA 1HO5A 3QFOA 1WARA 3RQZA 3THOB 3DSCA 4LTYA 4TUIA 4FBWA 5JPEA 1S3MA 3GVEA 5EQVA 1S8EA 1HP1A 2O8GA 4DHLA 2YVTA 2HYPA 3H68A 2WDFA 4JA7A 5JJTA 5B8IA 1XM7A 4KKZA 2NPPC 3E7BA 2QJCA 3H61A 3RL5A 3V4YA 2KKNA 1QFCA 1QHWA 2WDDA 3H62B 3C9FA 1S3NA 3RL3A 1WAO1 2CV9A 2Z72A 3DSDA 4UT3B 5JPFA 2BCDA 5C1VA 3AUZA 1S3LA 2R17A 2Z06A 2GJUA 4MP0A 4ZX2A 4F0ZA 3T1IA 5F3WA 2ZBMA 4ORBA 1S95A 2WDCA 5HPEA 2P6BA 2DFJA 4H1SA 3H63A 4Q7FA 1USHA 4ORAA 4LACC 4B2OA 2WDEA 1AUIA 5IOHA 1Z2XA 4KBPA 3THNA 3H67A 3QFMA 3TGHA 1W24A 3H64A 1Z2WA 2BQ8X 2NYMC 4LU9A 2HYOA 3ZU0A 1T70A 4O4KA 3P71C 3N5UA 1OI8A
chains in the Genus database with same CATH superfamily
5DNYA 1U32A 3QFKA 4UT3A 2YEQA 3H69A 3K7WC 4MOYA 3IB8A 1TCOA 1SU1A 1OIEA 2Q8UA 3H60A 3QG5C 4I5NC 3E7AA 4DT2A 4H1YP 2O8AA 4V0WA 3ZTVA 1IT6A 2IE3C 2Z1AA 3CK2A 2JOGA 2AHDA 3IVDA 4ZVZA 3KBPA 2USHA 1M63A 4OR9A 1T71A 3LL8A 4UWQA 1KBPA 3AV0A 4V0VA 2A22A 4H2IA 2IAEC 1MF8A 4FBKA 3K7VC 2QFPA 3EGGA 3ICFA 4H2FA 3RL4A 2QFRA 3HVQA 1UF3A 1FJMA 4FBQA 4O5GA 4FCXA 4H2GA 4DSYA 4YKEA 1XZWA 2HY1A 3DW8C 3EGHA 5INBA 4NZVA 3PSOA 4I5LC 4J6OA 4IYPC 3QFNA 4UT2A 1G5BA 1NNWA 1OIDA 3IVEA 1HPUA 3H66A 4O43A 2NXFA 3IB7A 4ORCA 5J28A 2XMOA 3C5WC 4G9JA 4IL1A 4M0VA 4WWLA 4XPNA 4TUGA 4O24A 1S70A 2NYLC 2IE4C 3JYFA 1II7A 5GTUA 1UTEA 4MOVA 3FLOA 4H2BA 1V73A 4JA9A 3PSNA 3E0JA 4V0XA 1JK7A 4HD0A 3FGAC 2BDXA 1HO5A 3QFOA 1WARA 3RQZA 3THOB 3DSCA 4LTYA 4TUIA 4FBWA 5JPEA 1S3MA 3GVEA 5EQVA 1S8EA 1HP1A 2DXLA 2O8GA 4DHLA 2YVTA 2HYPA 3H68A 2DXNA 2WDFA 4JA7A 5JJTA 5B8IA 3D03A 1XM7A 4KKZA 2NPPC 3E7BA 2QJCA 3H61A 3RL5A 3V4YA 2ZO9B 2KKNA 1QFCA 1QHWA 2WDDA 3H62B 3C9FA 1S3NA 3RL3A 1WAO1 2CV9A 2Z72A 3DSDA 4UT3B 5JPFA 2BCDA 5C1VA 3AUZA 1S3LA 2R17A 2Z06A 2GJUA 4MP0A 4ZX2A 4F0ZA 3T1IA 5F3WA 2ZBMA 4ORBA 1S95A 2WDCA 5HPEA 2P6BA 2DFJA 4H1SA 3H63A 4Q7FA 1USHA 4ORAA 4LACC 4B2OA 2WDEA 1AUIA 5IOHA 1Z2XA 4KBPA 3THNA 3H67A 3QFMA 3TGHA 1W24A 3H64A 1Z2WA 2BQ8X 2NYMC 4LU9A 2HYOA 3ZU0A 1T70A 4O4KA 2ZOAA 3P71C 3N5UA 1OI8A
chains in the Genus database with same CATH topology
5DNYA 1U32A 3QFKA 4UT3A 2YEQA 3H69A 3K7WC 4MOYA 3IB8A 1TCOA 1SU1A 1OIEA 2Q8UA 3H60A 3QG5C 4I5NC 3E7AA 4DT2A 4H1YP 2O8AA 4V0WA 3ZTVA 1IT6A 2IE3C 2Z1AA 3CK2A 2JOGA 2AHDA 3IVDA 4ZVZA 3KBPA 2USHA 1M63A 4OR9A 1T71A 3LL8A 4UWQA 1KBPA 3AV0A 4V0VA 2A22A 4H2IA 2IAEC 1MF8A 4FBKA 3K7VC 2QFPA 3EGGA 3ICFA 4H2FA 3RL4A 2QFRA 3HVQA 1UF3A 1FJMA 4FBQA 4O5GA 4FCXA 4H2GA 4DSYA 4YKEA 1XZWA 2HY1A 3DW8C 3EGHA 5INBA 4NZVA 3PSOA 4I5LC 4J6OA 4IYPC 3QFNA 4UT2A 1G5BA 1NNWA 1OIDA 3IVEA 1HPUA 3H66A 4O43A 2NXFA 3IB7A 4ORCA 5J28A 2XMOA 3C5WC 4G9JA 4IL1A 4M0VA 4WWLA 4XPNA 4TUGA 4O24A 1S70A 2NYLC 2IE4C 3JYFA 1II7A 5GTUA 1UTEA 4MOVA 3FLOA 4H2BA 1V73A 4JA9A 3PSNA 3E0JA 4V0XA 1JK7A 4HD0A 3FGAC 2BDXA 1HO5A 3QFOA 1WARA 3RQZA 3THOB 3DSCA 4LTYA 4TUIA 4FBWA 5JPEA 1S3MA 3GVEA 5EQVA 1S8EA 1HP1A 2DXLA 2O8GA 4DHLA 2YVTA 2HYPA 3H68A 2DXNA 2WDFA 4JA7A 5JJTA 5B8IA 3D03A 1XM7A 4KKZA 2NPPC 3E7BA 2QJCA 3H61A 3RL5A 3V4YA 2ZO9B 2KKNA 1QFCA 1QHWA 2WDDA 3H62B 3C9FA 1S3NA 3RL3A 1WAO1 2CV9A 2Z72A 3DSDA 4UT3B 5JPFA 2BCDA 5C1VA 3AUZA 1S3LA 2R17A 2Z06A 2GJUA 4MP0A 4ZX2A 4F0ZA 3T1IA 5F3WA 2ZBMA 4ORBA 1S95A 2WDCA 5HPEA 2P6BA 2DFJA 4H1SA 3H63A 4Q7FA 1USHA 4ORAA 4LACC 4B2OA 2WDEA 1AUIA 5IOHA 1Z2XA 4KBPA 3THNA 3H67A 3QFMA 3TGHA 1W24A 3H64A 1Z2WA 2BQ8X 2NYMC 4LU9A 2HYOA 3ZU0A 1T70A 4O4KA 2ZOAA 3P71C 3N5UA 1OI8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DNY A;  1U32 A;  3QFK A;  4UT3 A;  3H69 A;  3K7W C;  4MOY A;  3IB8 A;  1TCO A;  1SU1 A;  1OIE A;  2Q8U A;  3H60 A;  3QG5 C;  4I5N C;  3E7A A;  4DT2 A;  4H1Y P;  2O8A A;  4V0W A;  3ZTV A;  1IT6 A;  2IE3 C;  2Z1A A;  3CK2 A;  2JOG A;  2AHD A;  3IVD A;  4ZVZ A;  3KBP A;  2USH A;  1M63 A;  4OR9 A;  1T71 A;  3LL8 A;  4UWQ A;  1KBP A;  3AV0 A;  4V0V A;  2A22 A;  4H2I A;  2IAE C;  1MF8 A;  4FBK A;  3K7V C;  2QFP A;  3EGG A;  3ICF A;  4H2F A;  3RL4 A;  2QFR A;  3HVQ A;  1UF3 A;  1FJM A;  4FBQ A;  4O5G A;  4FCX A;  4H2G A;  4DSY A;  4YKE A;  1XZW A;  2HY1 A;  3DW8 C;  3EGH A;  5INB A;  4NZV A;  3PSO A;  4I5L C;  4J6O A;  4IYP C;  3QFN A;  4UT2 A;  1G5B A;  1NNW A;  1OID A;  3IVE A;  1HPU A;  3H66 A;  4O43 A;  2NXF A;  3IB7 A;  4ORC A;  5J28 A;  2XMO A;  3C5W C;  4G9J A;  4IL1 A;  4M0V A;  4WWL A;  4XPN A;  4TUG A;  4O24 A;  1S70 A;  2NYL C;  2IE4 C;  3JYF A;  1II7 A;  5GTU A;  1UTE A;  4MOV A;  4H2B A;  1V73 A;  4JA9 A;  3PSN A;  4V0X A;  1JK7 A;  4HD0 A;  3FGA C;  2BDX A;  1HO5 A;  3QFO A;  1WAR A;  3RQZ A;  3THO B;  3DSC A;  4LTY A;  4TUI A;  4FBW A;  5JPE A;  1S3M A;  3GVE A;  5EQV A;  1S8E A;  1HP1 A;  2O8G A;  4DHL A;  2YVT A;  2HYP A;  3H68 A;  2WDF A;  4JA7 A;  5JJT A;  5B8I A;  1XM7 A;  4KKZ A;  2NPP C;  3E7B A;  2QJC A;  3H61 A;  3RL5 A;  3V4Y A;  2KKN A;  1QFC A;  1QHW A;  2WDD A;  3H62 B;  3C9F A;  1S3N A;  3RL3 A;  1WAO 1;  2CV9 A;  2Z72 A;  3DSD A;  4UT3 B;  5JPF A;  2BCD A;  5C1V A;  3AUZ A;  1S3L A;  2R17 A;  2Z06 A;  2GJU A;  4MP0 A;  4ZX2 A;  4F0Z A;  3T1I A;  5F3W A;  2ZBM A;  4ORB A;  1S95 A;  2WDC A;  5HPE A;  2P6B A;  2DFJ A;  4H1S A;  3H63 A;  4Q7F A;  1USH A;  4ORA A;  4LAC C;  4B2O A;  2WDE A;  1AUI A;  5IOH A;  1Z2X A;  4KBP A;  3THN A;  3H67 A;  3QFM A;  3TGH A;  1W24 A;  3H64 A;  1Z2W A;  2BQ8 X;  2NYM C;  4LU9 A;  2HYO A;  3ZU0 A;  1T70 A;  4O4K A;  3P71 C;  3N5U A;  1OI8 A; 
#chains in the Genus database with same CATH topology
 5DNY A;  1U32 A;  3QFK A;  4UT3 A;  2YEQ A;  3H69 A;  3K7W C;  4MOY A;  3IB8 A;  1TCO A;  1SU1 A;  1OIE A;  2Q8U A;  3H60 A;  3QG5 C;  4I5N C;  3E7A A;  4DT2 A;  4H1Y P;  2O8A A;  4V0W A;  3ZTV A;  1IT6 A;  2IE3 C;  2Z1A A;  3CK2 A;  2JOG A;  2AHD A;  3IVD A;  4ZVZ A;  3KBP A;  2USH A;  1M63 A;  4OR9 A;  1T71 A;  3LL8 A;  4UWQ A;  1KBP A;  3AV0 A;  4V0V A;  2A22 A;  4H2I A;  2IAE C;  1MF8 A;  4FBK A;  3K7V C;  2QFP A;  3EGG A;  3ICF A;  4H2F A;  3RL4 A;  2QFR A;  3HVQ A;  1UF3 A;  1FJM A;  4FBQ A;  4O5G A;  4FCX A;  4H2G A;  4DSY A;  4YKE A;  1XZW A;  2HY1 A;  3DW8 C;  3EGH A;  5INB A;  4NZV A;  3PSO A;  4I5L C;  4J6O A;  4IYP C;  3QFN A;  4UT2 A;  1G5B A;  1NNW A;  1OID A;  3IVE A;  1HPU A;  3H66 A;  4O43 A;  2NXF A;  3IB7 A;  4ORC A;  5J28 A;  2XMO A;  3C5W C;  4G9J A;  4IL1 A;  4M0V A;  4WWL A;  4XPN A;  4TUG A;  4O24 A;  1S70 A;  2NYL C;  2IE4 C;  3JYF A;  1II7 A;  5GTU A;  1UTE A;  4MOV A;  3FLO A;  4H2B A;  1V73 A;  4JA9 A;  3PSN A;  3E0J A;  4V0X A;  1JK7 A;  4HD0 A;  3FGA C;  2BDX A;  1HO5 A;  3QFO A;  1WAR A;  3RQZ A;  3THO B;  3DSC A;  4LTY A;  4TUI A;  4FBW A;  5JPE A;  1S3M A;  3GVE A;  5EQV A;  1S8E A;  1HP1 A;  2DXL A;  2O8G A;  4DHL A;  2YVT A;  2HYP A;  3H68 A;  2DXN A;  2WDF A;  4JA7 A;  5JJT A;  5B8I A;  3D03 A;  1XM7 A;  4KKZ A;  2NPP C;  3E7B A;  2QJC A;  3H61 A;  3RL5 A;  3V4Y A;  2ZO9 B;  2KKN A;  1QFC A;  1QHW A;  2WDD A;  3H62 B;  3C9F A;  1S3N A;  3RL3 A;  1WAO 1;  2CV9 A;  2Z72 A;  3DSD A;  4UT3 B;  5JPF A;  2BCD A;  5C1V A;  3AUZ A;  1S3L A;  2R17 A;  2Z06 A;  2GJU A;  4MP0 A;  4ZX2 A;  4F0Z A;  3T1I A;  5F3W A;  2ZBM A;  4ORB A;  1S95 A;  2WDC A;  5HPE A;  2P6B A;  2DFJ A;  4H1S A;  3H63 A;  4Q7F A;  1USH A;  4ORA A;  4LAC C;  4B2O A;  2WDE A;  1AUI A;  5IOH A;  1Z2X A;  4KBP A;  3THN A;  3H67 A;  3QFM A;  3TGH A;  1W24 A;  3H64 A;  1Z2W A;  2BQ8 X;  2NYM C;  4LU9 A;  2HYO A;  3ZU0 A;  1T70 A;  4O4K A;  2ZOA A;  3P71 C;  3N5U A;  1OI8 A; 
#chains in the Genus database with same CATH homology
 5DNY A;  1U32 A;  3QFK A;  4UT3 A;  2YEQ A;  3H69 A;  3K7W C;  4MOY A;  3IB8 A;  1TCO A;  1SU1 A;  1OIE A;  2Q8U A;  3H60 A;  3QG5 C;  4I5N C;  3E7A A;  4DT2 A;  4H1Y P;  2O8A A;  4V0W A;  3ZTV A;  1IT6 A;  2IE3 C;  2Z1A A;  3CK2 A;  2JOG A;  2AHD A;  3IVD A;  4ZVZ A;  3KBP A;  2USH A;  1M63 A;  4OR9 A;  1T71 A;  3LL8 A;  4UWQ A;  1KBP A;  3AV0 A;  4V0V A;  2A22 A;  4H2I A;  2IAE C;  1MF8 A;  4FBK A;  3K7V C;  2QFP A;  3EGG A;  3ICF A;  4H2F A;  3RL4 A;  2QFR A;  3HVQ A;  1UF3 A;  1FJM A;  4FBQ A;  4O5G A;  4FCX A;  4H2G A;  4DSY A;  4YKE A;  1XZW A;  2HY1 A;  3DW8 C;  3EGH A;  5INB A;  4NZV A;  3PSO A;  4I5L C;  4J6O A;  4IYP C;  3QFN A;  4UT2 A;  1G5B A;  1NNW A;  1OID A;  3IVE A;  1HPU A;  3H66 A;  4O43 A;  2NXF A;  3IB7 A;  4ORC A;  5J28 A;  2XMO A;  3C5W C;  4G9J A;  4IL1 A;  4M0V A;  4WWL A;  4XPN A;  4TUG A;  4O24 A;  1S70 A;  2NYL C;  2IE4 C;  3JYF A;  1II7 A;  5GTU A;  1UTE A;  4MOV A;  3FLO A;  4H2B A;  1V73 A;  4JA9 A;  3PSN A;  3E0J A;  4V0X A;  1JK7 A;  4HD0 A;  3FGA C;  2BDX A;  1HO5 A;  3QFO A;  1WAR A;  3RQZ A;  3THO B;  3DSC A;  4LTY A;  4TUI A;  4FBW A;  5JPE A;  1S3M A;  3GVE A;  5EQV A;  1S8E A;  1HP1 A;  2DXL A;  2O8G A;  4DHL A;  2YVT A;  2HYP A;  3H68 A;  2DXN A;  2WDF A;  4JA7 A;  5JJT A;  5B8I A;  3D03 A;  1XM7 A;  4KKZ A;  2NPP C;  3E7B A;  2QJC A;  3H61 A;  3RL5 A;  3V4Y A;  2ZO9 B;  2KKN A;  1QFC A;  1QHW A;  2WDD A;  3H62 B;  3C9F A;  1S3N A;  3RL3 A;  1WAO 1;  2CV9 A;  2Z72 A;  3DSD A;  4UT3 B;  5JPF A;  2BCD A;  5C1V A;  3AUZ A;  1S3L A;  2R17 A;  2Z06 A;  2GJU A;  4MP0 A;  4ZX2 A;  4F0Z A;  3T1I A;  5F3W A;  2ZBM A;  4ORB A;  1S95 A;  2WDC A;  5HPE A;  2P6B A;  2DFJ A;  4H1S A;  3H63 A;  4Q7F A;  1USH A;  4ORA A;  4LAC C;  4B2O A;  2WDE A;  1AUI A;  5IOH A;  1Z2X A;  4KBP A;  3THN A;  3H67 A;  3QFM A;  3TGH A;  1W24 A;  3H64 A;  1Z2W A;  2BQ8 X;  2NYM C;  4LU9 A;  2HYO A;  3ZU0 A;  1T70 A;  4O4K A;  2ZOA A;  3P71 C;  3N5U A;  1OI8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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