1TWA | Genus

Total Genus 0

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	0
sequence length	46
structure length	46
Chain Sequence	ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transcription
publication title	Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center. pubmed doi rcsb
molecule keywords	DNA-directed RNA polymerase II largest subunit
structure length	46
sequence length	46
ec nomenclature
pdb deposition date	2004-06-30

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
L	PF03604	DNA_RNApol_7kD	DNA directed RNA polymerase, 7 kDa subunit

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.20.28.30	Mainly Beta	Single Sheet	Rubrerythrin, domain 2	RNA polymerase ii, chain L	1twaL00

1R9TL 4C3IL 2Y0SP 4BY7L 1SFOL 5M3ML 3HOXL 4BXXL 2R7ZL 3S1RL 1TWFL 3GTQL 3HKZP 3S16L 3S15L 4A3LL 4X6AL 1I6HL 3S2DL 4A3IL 4A3KL 4A3GL 3S14L 1Y1VL 5C4XL 2WAQP 4A3FL 5FLML 3S2HL 1TWHL 4Y52L 3RZOL 1Y1WL 2R92L 2YU9L 3PO2L 4BY1L 5IP7L 4A3JL 5IYDL 3I4ML 4C3HL 5M5XL 1WCML 3HOVL 3H3VM 3M3YL 3HOUL 4QIWP 1K83L 2B63L 1TWGL 3HOZL 5C3EL 4A3DL 3FKIL 4Y7NL 1TWAL 2R93L 4BBRL 5M3FL 3GTLL 3S17L 3S1QL 3PO3L 3GTML 4AYBP 2E2IL 3GTOL 5IYCL 2JA7L 3HOWL 3S1ML 2NVYL 4BBSL 2JA5L 5C4JL 2VUML 3HOYL 3GTPL 3I4NL 2E2JL 3GTKL 5IYBL 2NVTL 1I3QL 5C44L 4A3EL 2JA6L 2E2HL 3GTGL 3K7AL 2WB1P 5M5WL 1TWCL 5FJ8L 4C3JL 3GTJL 4C2M1 4A3ML 3CQZL 1I50L 3M4OL 2JA8L 4A3CL 3S1NL 5IP9L 2NVQL 4A3BL 2NVXL 3H0GL 4A93L 5M5YL 2PMZP 3RZDL
chains in the Genus database with same CATH superfamily

2C6BA 4AR4A 4C3IL 3PIP1 4JAFA 1SFOL 2NYDA 3S1RL 3GTQL 3LWOB 4X6AL 4A3IL 1S2ZA 2XJRA 4LHNA 2M6PA 2JI3A 2PVXA 1YUZA 4JADA 1PFUA 3H99A 3KYWA 1ODHA 3LPEB 5K2ME 2AQCA 2R92L 3PO2L 2XJSA 2DSXA 4A3JL 5AN9H 1LKMA 1BFYA 3I4ML 5MFZA 4RXNA 3M3YL 1LKOA 2ZIXA 1TWGL 4A3DL 3LWQB 1TWAL 2R93L 4BBRL 2M4VA 4JAEA 5M3FL 3GTLL 3S17L 3PL5A 3J7Z1 3S1ML 3LWRB 1YK5A 4AI3A 1E8JA 3GTPL 1PZXA 3I4NL 2K2DA 4ZN1B 1QQTA 1TWCL 1VZGA 4C3JL 2KKDA 2B5ID 3SS2A 1I50L 3PKJA 2HVYC 4AI2A 2A69D 4A3BL 1QYBA 1RDGA 3A44A 2O5JD 1LTLA 1RYTA 2Y0SP 3HOXL 4TPUA 2R7ZL 1SMUA 1CADA 2A6HD 3HKZP 3S15L 1R0IA 3KYUA 1I6HL 2ERSA 4A3KL 1BRFA 2C6AA 4A3GL 2XJQA 3MSUA 4GS7D 1TWHL 4Y52L 4G6BA 3VPBE 4LHLA 3HJYB 3WWNB 5AI3A 2VL6A 2GMGA 2AUSB 2JI2A 4BY1L 1P7PA 1SMWA 3H97A 5GAGc 2LCQA 1YUXA 1WCML 1T9QA 1H7VA 1R0HA 5IY0A 3B0AB 1T9PA 3P8BA 5AI2A 3HOZL 5C3EL 1FHMA 5DM61 5H1Sc 1RWDA 2RDVA 5JVG1 3GTML 4XXBB 4AYBP 3HOWL 3MPSA 2EY4E 3HJWB 4POGA 1BQ9A 2E2JL 1B2JA 2CR8A 5C44L 4A3EL 2E2HL 3GTGL 5FJ8L 4K9FA 4UY81 1JYBA 3QVDA 4WFN1 1DVBA 2JA8L 1S30A 2V0EA 5MGNA 1IROA 2CKAA 1IW7D 1OWCA 4A93L 3B08B 2PMZP 4BY7L 4BXXL 2KN9A 1NXEA 1DX8A 2CKCA 1IRNA 4B8CD 2Z3RB 5GADc 4POFA 3PIO1 5C4XL 1VCXA 4A3FL 5FLML 2XJPA 4AR6A 3RYGA 5JVH1 1LKPA 3RZOL 4AHYA 3MQKB 3P2AA 1BE7A 4JAGA 2YU9L 3HAXC 2Z3QB 3PWFA 5MLC3 3LWPB 5IYDL 2XJVA 1YK4A 2PSMC 1PFVA 4C3HL 5M5XL 3RZTA 1S24A 4V196 3HOUL 2XJUA 2QL0A 3QQCE 4AR3A 3ZG6A 4Y7NL 1IU5A 2JI1A 2XJTA 3PO3L 3H9CA 2A68D 5IYCL 2AYJA 2JA7L 2NVYL 1RDVA 4XGHA 1C09A 5C4JL 2RFKB 2VUML 3PZAA 4AI1A 3PKIA 5IYBL 2NVTL 2HR5A 4AHZA 2JA6L 1CAAA 2WB1P 5MF6A 5M5WL 2M6OA 4C2M1 1OWBA 4A3ML 3CQZL 1SMMA 1VZHA 4A3CL 3S1NL 3KYYA 2BE5D 1R0FA 5MFPA 5RXNA 6RXNA 4AI0A 8RXNA 1VZIA 2NVXL 3H0GL 3KYVA 1QCVA 1R9TL 2APOB 4YWMA 5M3ML 3LWVB 1B71A 1B2OA 1TWFL 3S16L 3K35A 4AHXA 4A3LL 3S2DL 7RXNA 2MS3A 3RZ6A 3S14L 1Y1VL 2M4YA 1ZRPA 1F4LA 2WAQP 3J7Y1 2A6ED 3S2HL 4YWLA 1Y1WL 5DM71 5IP7L 3KYXA 3LNLA 3WWLA 3HOVL 3H3VM 5GAEc 1PFWA 4QIWP 1K83L 2B63L 1B13A 1RB9A 1PFYA 1NNQA 1BQ8A 3FKIL 1RYQA 3S1QL 5EIOC 2E2IL 3GTOL 4BBSL 2PPTA 2JA5L 4E6YA 3JR7A 4ME3A 2PVEA 5EINC 3HOYL 1NXGA 3GTKL 4U671 1I3QL 2H12A 3K7AL 2L0ZA 3GTJL 2PYAA 2J9UB 1FHHA 4AHWA 1Z92B 3H9BA 3IU3I 3FDJA 3M4OL 1R0JA 1T9OA 1R0GA 5GAHc 5IP9L 4TVMA 1WJVA 2ERJA 3NFPI 2NVQL 4ZN3B 2V0FA 1YV1A 2V3BB 4AR5A 5M5YL 1IU6A 3RZDL
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1R9T L;  4C3I L;  2Y0S P;  4BY7 L;  1SFO L;  5M3M L;  3HOX L;  4BXX L;  2R7Z L;  3S1R L;  1TWF L;  3GTQ L;  3HKZ P;  3S16 L;  3S15 L;  4A3L L;  4X6A L;  1I6H L;  3S2D L;  4A3I L;  4A3K L;  4A3G L;  3S14 L;  1Y1V L;  5C4X L;  2WAQ P;  4A3F L;  5FLM L;  3S2H L;  1TWH L;  4Y52 L;  3RZO L;  1Y1W L;  2R92 L;  2YU9 L;  3PO2 L;  4BY1 L;  5IP7 L;  4A3J L;  5IYD L;  3I4M L;  4C3H L;  5M5X L;  1WCM L;  3HOV L;  3H3V M;  3M3Y L;  3HOU L;  4QIW P;  1K83 L;  2B63 L;  1TWG L;  3HOZ L;  5C3E L;  4A3D L;  3FKI L;  4Y7N L;  1TWA L;  2R93 L;  4BBR L;  5M3F L;  3GTL L;  3S17 L;  3S1Q L;  3PO3 L;  3GTM L;  4AYB P;  2E2I L;  3GTO L;  5IYC L;  2JA7 L;  3HOW L;  3S1M L;  2NVY L;  4BBS L;  2JA5 L;  5C4J L;  2VUM L;  3HOY L;  3GTP L;  3I4N L;  2E2J L;  3GTK L;  5IYB L;  2NVT L;  1I3Q L;  5C44 L;  4A3E L;  2JA6 L;  2E2H L;  3GTG L;  3K7A L;  2WB1 P;  5M5W L;  1TWC L;  5FJ8 L;  4C3J L;  3GTJ L;  4C2M 1;  4A3M L;  3CQZ L;  1I50 L;  3M4O L;  2JA8 L;  4A3C L;  3S1N L;  5IP9 L;  2NVQ L;  4A3B L;  2NVX L;  3H0G L;  4A93 L;  5M5Y L;  2PMZ P;  3RZD L; 
#chains in the Genus database with same CATH topology
 2C6B A;  4AR4 A;  4C3I L;  3PIP 1;  4JAF A;  1SFO L;  2NYD A;  3S1R L;  3GTQ L;  3LWO B;  4X6A L;  4A3I L;  1S2Z A;  2XJR A;  4LHN A;  2M6P A;  2JI3 A;  2PVX A;  1YUZ A;  4JAD A;  1PFU A;  3H99 A;  3KYW A;  1ODH A;  3LPE B;  5K2M E;  2AQC A;  2R92 L;  3PO2 L;  2XJS A;  2DSX A;  4A3J L;  5AN9 H;  1LKM A;  1BFY A;  3I4M L;  5MFZ A;  4RXN A;  3M3Y L;  1LKO A;  2ZIX A;  1TWG L;  4A3D L;  3LWQ B;  1TWA L;  2R93 L;  4BBR L;  2M4V A;  4JAE A;  5M3F L;  3GTL L;  3S17 L;  3PL5 A;  3J7Z 1;  3S1M L;  3LWR B;  1YK5 A;  4AI3 A;  1E8J A;  3GTP L;  1PZX A;  3I4N L;  2K2D A;  4ZN1 B;  1QQT A;  1TWC L;  1VZG A;  4C3J L;  2KKD A;  2B5I D;  3SS2 A;  1I50 L;  3PKJ A;  2HVY C;  4AI2 A;  2A69 D;  4A3B L;  1QYB A;  1RDG A;  3A44 A;  2O5J D;  1LTL A;  1RYT A;  2Y0S P;  3HOX L;  4TPU A;  2R7Z L;  1SMU A;  1CAD A;  2A6H D;  3HKZ P;  3S15 L;  1R0I A;  3KYU A;  1I6H L;  2ERS A;  4A3K L;  1BRF A;  2C6A A;  4A3G L;  2XJQ A;  3MSU A;  4GS7 D;  1TWH L;  4Y52 L;  4G6B A;  3VPB E;  4LHL A;  3HJY B;  3WWN B;  5AI3 A;  2VL6 A;  2GMG A;  2AUS B;  2JI2 A;  4BY1 L;  1P7P A;  1SMW A;  3H97 A;  5GAG c;  2LCQ A;  1YUX A;  1WCM L;  1T9Q A;  1H7V A;  1R0H A;  5IY0 A;  3B0A B;  1T9P A;  3P8B A;  5AI2 A;  3HOZ L;  5C3E L;  1FHM A;  5DM6 1;  5H1S c;  1RWD A;  2RDV A;  5JVG 1;  3GTM L;  4XXB B;  4AYB P;  3HOW L;  3MPS A;  2EY4 E;  3HJW B;  4POG A;  1BQ9 A;  2E2J L;  1B2J A;  2CR8 A;  5C44 L;  4A3E L;  2E2H L;  3GTG L;  5FJ8 L;  4K9F A;  4UY8 1;  1JYB A;  3QVD A;  4WFN 1;  1DVB A;  2JA8 L;  1S30 A;  2V0E A;  5MGN A;  1IRO A;  2CKA A;  1IW7 D;  1OWC A;  4A93 L;  3B08 B;  2PMZ P;  4BY7 L;  4BXX L;  2KN9 A;  1NXE A;  1DX8 A;  2CKC A;  1IRN A;  4B8C D;  2Z3R B;  5GAD c;  4POF A;  3PIO 1;  5C4X L;  1VCX A;  4A3F L;  5FLM L;  2XJP A;  4AR6 A;  3RYG A;  5JVH 1;  1LKP A;  3RZO L;  4AHY A;  3MQK B;  3P2A A;  1BE7 A;  4JAG A;  2YU9 L;  3HAX C;  2Z3Q B;  3PWF A;  5MLC 3;  3LWP B;  5IYD L;  2XJV A;  1YK4 A;  2PSM C;  1PFV A;  4C3H L;  5M5X L;  3RZT A;  1S24 A;  4V19 6;  3HOU L;  2XJU A;  2QL0 A;  3QQC E;  4AR3 A;  3ZG6 A;  4Y7N L;  1IU5 A;  2JI1 A;  2XJT A;  3PO3 L;  3H9C A;  2A68 D;  5IYC L;  2AYJ A;  2JA7 L;  2NVY L;  1RDV A;  4XGH A;  1C09 A;  5C4J L;  2RFK B;  2VUM L;  3PZA A;  4AI1 A;  3PKI A;  5IYB L;  2NVT L;  2HR5 A;  4AHZ A;  2JA6 L;  1CAA A;  2WB1 P;  5MF6 A;  5M5W L;  2M6O A;  4C2M 1;  1OWB A;  4A3M L;  3CQZ L;  1SMM A;  1VZH A;  4A3C L;  3S1N L;  3KYY A;  2BE5 D;  1R0F A;  5MFP A;  5RXN A;  6RXN A;  4AI0 A;  8RXN A;  1VZI A;  2NVX L;  3H0G L;  3KYV A;  1QCV A;  1R9T L;  2APO B;  4YWM A;  5M3M L;  3LWV B;  1B71 A;  1B2O A;  1TWF L;  3S16 L;  3K35 A;  4AHX A;  4A3L L;  3S2D L;  7RXN A;  2MS3 A;  3RZ6 A;  3S14 L;  1Y1V L;  2M4Y A;  1ZRP A;  1F4L A;  2WAQ P;  3J7Y 1;  2A6E D;  3S2H L;  4YWL A;  1Y1W L;  5DM7 1;  5IP7 L;  3KYX A;  3LNL A;  3WWL A;  3HOV L;  3H3V M;  5GAE c;  1PFW A;  4QIW P;  1K83 L;  2B63 L;  1B13 A;  1RB9 A;  1PFY A;  1NNQ A;  1BQ8 A;  3FKI L;  1RYQ A;  3S1Q L;  5EIO C;  2E2I L;  3GTO L;  4BBS L;  2PPT A;  2JA5 L;  4E6Y A;  3JR7 A;  4ME3 A;  2PVE A;  5EIN C;  3HOY L;  1NXG A;  3GTK L;  4U67 1;  1I3Q L;  2H12 A;  3K7A L;  2L0Z A;  3GTJ L;  2PYA A;  2J9U B;  1FHH A;  4AHW A;  1Z92 B;  3H9B A;  3IU3 I;  3FDJ A;  3M4O L;  1R0J A;  1T9O A;  1R0G A;  5GAH c;  5IP9 L;  4TVM A;  1WJV A;  2ERJ A;  3NFP I;  2NVQ L;  4ZN3 B;  2V0F A;  1YV1 A;  2V3B B;  4AR5 A;  5M5Y L;  1IU6 A;  3RZD L; 
#chains in the Genus database with same CATH homology
 1R9T L;  4C3I L;  2Y0S P;  4BY7 L;  1SFO L;  5M3M L;  3HOX L;  4BXX L;  2R7Z L;  3S1R L;  1TWF L;  3GTQ L;  3HKZ P;  3S16 L;  3S15 L;  4A3L L;  4X6A L;  1I6H L;  3S2D L;  4A3I L;  4A3K L;  4A3G L;  3S14 L;  1Y1V L;  5C4X L;  2WAQ P;  4A3F L;  5FLM L;  3S2H L;  1TWH L;  4Y52 L;  3RZO L;  1Y1W L;  2R92 L;  2YU9 L;  3PO2 L;  4BY1 L;  5IP7 L;  4A3J L;  5IYD L;  3I4M L;  4C3H L;  5M5X L;  1WCM L;  3HOV L;  3H3V M;  3M3Y L;  3HOU L;  4QIW P;  1K83 L;  2B63 L;  1TWG L;  3HOZ L;  5C3E L;  4A3D L;  3FKI L;  4Y7N L;  1TWA L;  2R93 L;  4BBR L;  5M3F L;  3GTL L;  3S17 L;  3S1Q L;  3PO3 L;  3GTM L;  4AYB P;  2E2I L;  3GTO L;  5IYC L;  2JA7 L;  3HOW L;  3S1M L;  2NVY L;  4BBS L;  2JA5 L;  5C4J L;  2VUM L;  3HOY L;  3GTP L;  3I4N L;  2E2J L;  3GTK L;  5IYB L;  2NVT L;  1I3Q L;  5C44 L;  4A3E L;  2JA6 L;  2E2H L;  3GTG L;  3K7A L;  2WB1 P;  5M5W L;  1TWC L;  5FJ8 L;  4C3J L;  3GTJ L;  4C2M 1;  4A3M L;  3CQZ L;  1I50 L;  3M4O L;  2JA8 L;  4A3C L;  3S1N L;  5IP9 L;  2NVQ L;  4A3B L;  2NVX L;  3H0G L;  4A93 L;  5M5Y L;  2PMZ P;  3RZD L;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1TWAL

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations