1TWHL

Rna polymerase ii complexed with 2'datp
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
publication title Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
pubmed doi rcsb
molecule keywords DNA-directed RNA polymerase II largest subunit
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2004-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 1twhL00
5M3FL 3S17L 3S1ML 3GTML 1I50L 2R92L 5C3EL 2NVYL 4BBRL 3GTQL 4A93L 3HOZL 4BY1L 4BXXL 1Y1VL 4A3ML 3GTJL 4A3IL 1I3QL 2E2JL 2JA5L 2YU9L 3GTLL 4A3DL 4C3IL 3H0GL 2NVTL 4C3HL 2R93L 4Y52L 2JA8L 1TWFL 3H3VM 2PMZP 4A3LL 4A3GL 3S1RL 4A3CL 5M5XL 3HKZP 1R9TL 1TWGL 3GTKL 3HOYL 3S2HL 1SFOL 2JA6L 4A3EL 3HOWL 3I4NL 4Y7NL 4X6AL 4A3KL 3RZDL 4BBSL 3HOVL 3S14L 3S2DL 3HOUL 5M3ML 1TWCL 2WAQP 3M4OL 5C44L 5M5YL 5IP9L 1Y1WL 1TWHL 4AYBP 2VUML 3S15L 2R7ZL 3CQZL 5C4JL 4BY7L 1TWAL 3M3YL 3GTOL 5IP7L 5IYDL 3GTPL 5IYCL 2E2HL 4A3FL 4A3BL 3S1NL 5FLML 5FJ8L 5C4XL 2NVXL 3GTGL 2JA7L 1K83L 4C3JL 3I4ML 4QIWP 3HOXL 2B63L 3S1QL 3PO3L 3FKIL 2WB1P 3RZOL 1WCML 3PO2L 2Y0SP 4A3JL 2E2IL 3S16L 5IYBL 2NVQL 4C2M1 5M5WL 1I6HL 3K7AL
chains in the Genus database with same CATH superfamily
5MLC3 1SMUA 2XJSA 1I50L 2Z3RB 1OWBA 2M4VA 4JADA 5C3EL 3RYGA 1R0HA 5GADc 3GTQL 1QCVA 2V0FA 4V196 5GAGc 5MGNA 3RZ6A 3MSUA 1Y1VL 1QQTA 3GTJL 2E2JL 1IRNA 2MS3A 2YU9L 4A3DL 1T9OA 5AI2A 1TWFL 5RXNA 2PMZP 2PPTA 4A3GL 3QVDA 3S1RL 1VZGA 4A3CL 1T9QA 2K2DA 1R9TL 1TWGL 3GTKL 1NXEA 1SFOL 1BFYA 1PFYA 5AN9H 3HJYB 1ZRPA 2ERJA 3H99A 4LHLA 1Z92B 1VZIA 4TVMA 3HOVL 3KYYA 5MFPA 2BE5D 1H7VA 4WFN1 1E8JA 1YK4A 1B71A 1TWAL 2QL0A 2PYAA 5H1Sc 3B08B 4A3FL 2E2HL 4A3BL 3S1NL 5FLML 2NVXL 2JA7L 3I4ML 7RXNA 3NFPI 2HVYC 4YWLA 4AR6A 2A69D 5MF6A 3S16L 3PIO1 1RWDA 2KKDA 5IYBL 2JI1A 4XGHA 2B5ID 1I6HL 1CAAA 5JVH1 3S1ML 2R92L 4XXBB 2ERSA 3K35A 2JI3A 2RDVA 1VCXA 1RYQA 2CR8A 4RXNA 4TPUA 3LWRB 1IW7D 3KYXA 1PFVA 4AR5A 3PWFA 3FDJA 4A3ML 3H9CA 1BQ8A 1B13A 3WWNB 3GTLL 1RYTA 4C3HL 2XJVA 3B0AB 3KYWA 1S24A 1IROA 1VZHA 3LNLA 2L0ZA 2DSXA 3KYUA 5M5XL 3HKZP 5JVG1 2H12A 2XJRA 4B8CD 2EY4E 5MFZA 3I4NL 2NYDA 4AI3A 4E6YA 4BBSL 1LTLA 1F4LA 1TWCL 4JAFA 2WAQP 4U671 2XJPA 3M4OL 5M5YL 1Y1WL 3ZG6A 1YUZA 1TWHL 1PFWA 1YV1A 1DVBA 5IY0A 4AHZA 3S15L 3JR7A 1OWCA 2R7ZL 4POFA 4AI1A 2V0EA 3MPSA 1B2JA 3M3YL 5IYDL 2M6OA 4POGA 1R0JA 5IYCL 5C4XL 3GTGL 1K83L 2XJUA 1BE7A 2C6BA 3PO3L 3FKIL 2WB1P 4AHXA 3RZOL 1WCML 1B2OA 2Y0SP 4A3JL 2E2IL 2NVQL 4JAGA 3K7AL 5M3FL 3S17L 2HR5A 3PIP1 2M6PA 4AI2A 3HOZL 1BQ9A 3LWQB 2AYJA 4ME3A 1IU6A 3SS2A 2JA5L 2CKCA 5GAHc 1YUXA 4LHNA 4C3IL 3H97A 6RXNA 1IU5A 2AUSB 3WWLA 2A6ED 2RFKB 1RDGA 3VPBE 2A68D 4ZN1B 3P2AA 2LCQA 4A3EL 1SMMA 1BRFA 4Y7NL 3IU3I 4X6AL 4A3KL 1R0GA 2C6AA 2PVEA 3PZAA 5M3ML 5IP9L 4AYBP 4YWMA 1PFUA 4AR3A 1S30A 3CQZL 2O5JD 5C4JL 5AI3A 5IP7L 2CKAA 1S2ZA 1LKOA 3H9BA 1PZXA 4GS7D 3QQCE 8RXNA 2PVXA 3HOXL 2B63L 3S1QL 2J9UB 2A6HD 4AHYA 3PO2L 3J7Z1 2Z3QB 3LWVB 4C2M1 5M5WL 4BBRL 3A44A 1RB9A 3GTML 1WJVA 5DM71 3KYVA 2NVYL 4A93L 3LWPB 4G6BA 5K2ME 1RDVA 4BY1L 4BXXL 5EIOC 1DX8A 4A3IL 2JI2A 1I3QL 3LPEB 3H0GL 2NVTL 2R93L 4Y52L 2JA8L 3H3VM 1R0IA 1R0FA 4A3LL 3RZTA 3PL5A 2GMGA 2AQCA 4UY81 5EINC 3LWOB 3J7Y1 1LKMA 1LKPA 1ODHA 2VL6A 3HOYL 2PSMC 3S2HL 2JA6L 1FHMA 3HOWL 4AHWA 1CADA 1NXGA 1NNQA 1YK5A 3RZDL 3S14L 2XJTA 3S2DL 4K9FA 3HAXC 3HOUL 2APOB 5C44L 4JAEA 2VUML 3PKJA 5GAEc 4BY7L 1SMWA 2ZIXA 2M4YA 3GTOL 3MQKB 1FHHA 3GTPL 1P7PA 3P8BA 3HJWB 5FJ8L 3PKIA 4AR4A 4C3JL 4AI0A 4QIWP 2KN9A 4ZN3B 2XJQA 1QYBA 1C09A 1JYBA 5DM61 2V3BB 1T9PA
chains in the Genus database with same CATH topology
5M3FL 3S17L 3S1ML 3GTML 1I50L 2R92L 5C3EL 2NVYL 4BBRL 3GTQL 4A93L 3HOZL 4BY1L 4BXXL 1Y1VL 4A3ML 3GTJL 4A3IL 1I3QL 2E2JL 2JA5L 2YU9L 3GTLL 4A3DL 4C3IL 3H0GL 2NVTL 4C3HL 2R93L 4Y52L 2JA8L 1TWFL 3H3VM 2PMZP 4A3LL 4A3GL 3S1RL 4A3CL 5M5XL 3HKZP 1R9TL 1TWGL 3GTKL 3HOYL 3S2HL 1SFOL 2JA6L 4A3EL 3HOWL 3I4NL 4Y7NL 4X6AL 4A3KL 3RZDL 4BBSL 3HOVL 3S14L 3S2DL 3HOUL 5M3ML 1TWCL 2WAQP 3M4OL 5C44L 5M5YL 5IP9L 1Y1WL 1TWHL 4AYBP 2VUML 3S15L 2R7ZL 3CQZL 5C4JL 4BY7L 1TWAL 3M3YL 3GTOL 5IP7L 5IYDL 3GTPL 5IYCL 2E2HL 4A3FL 4A3BL 3S1NL 5FLML 5FJ8L 5C4XL 2NVXL 3GTGL 2JA7L 1K83L 4C3JL 3I4ML 4QIWP 3HOXL 2B63L 3S1QL 3PO3L 3FKIL 2WB1P 3RZOL 1WCML 3PO2L 2Y0SP 4A3JL 2E2IL 3S16L 5IYBL 2NVQL 4C2M1 5M5WL 1I6HL 3K7AL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5M3F L;  3S17 L;  3S1M L;  3GTM L;  1I50 L;  2R92 L;  5C3E L;  2NVY L;  4BBR L;  3GTQ L;  4A93 L;  3HOZ L;  4BY1 L;  4BXX L;  1Y1V L;  4A3M L;  3GTJ L;  4A3I L;  1I3Q L;  2E2J L;  2JA5 L;  2YU9 L;  3GTL L;  4A3D L;  4C3I L;  3H0G L;  2NVT L;  4C3H L;  2R93 L;  4Y52 L;  2JA8 L;  1TWF L;  3H3V M;  2PMZ P;  4A3L L;  4A3G L;  3S1R L;  4A3C L;  5M5X L;  3HKZ P;  1R9T L;  1TWG L;  3GTK L;  3HOY L;  3S2H L;  1SFO L;  2JA6 L;  4A3E L;  3HOW L;  3I4N L;  4Y7N L;  4X6A L;  4A3K L;  3RZD L;  4BBS L;  3HOV L;  3S14 L;  3S2D L;  3HOU L;  5M3M L;  1TWC L;  2WAQ P;  3M4O L;  5C44 L;  5M5Y L;  5IP9 L;  1Y1W L;  1TWH L;  4AYB P;  2VUM L;  3S15 L;  2R7Z L;  3CQZ L;  5C4J L;  4BY7 L;  1TWA L;  3M3Y L;  3GTO L;  5IP7 L;  5IYD L;  3GTP L;  5IYC L;  2E2H L;  4A3F L;  4A3B L;  3S1N L;  5FLM L;  5FJ8 L;  5C4X L;  2NVX L;  3GTG L;  2JA7 L;  1K83 L;  4C3J L;  3I4M L;  4QIW P;  3HOX L;  2B63 L;  3S1Q L;  3PO3 L;  3FKI L;  2WB1 P;  3RZO L;  1WCM L;  3PO2 L;  2Y0S P;  4A3J L;  2E2I L;  3S16 L;  5IYB L;  2NVQ L;  4C2M 1;  5M5W L;  1I6H L;  3K7A L; 
#chains in the Genus database with same CATH topology
 5MLC 3;  1SMU A;  2XJS A;  1I50 L;  2Z3R B;  1OWB A;  2M4V A;  4JAD A;  5C3E L;  3RYG A;  1R0H A;  5GAD c;  3GTQ L;  1QCV A;  2V0F A;  4V19 6;  5GAG c;  5MGN A;  3RZ6 A;  3MSU A;  1Y1V L;  1QQT A;  3GTJ L;  2E2J L;  1IRN A;  2MS3 A;  2YU9 L;  4A3D L;  1T9O A;  5AI2 A;  1TWF L;  5RXN A;  2PMZ P;  2PPT A;  4A3G L;  3QVD A;  3S1R L;  1VZG A;  4A3C L;  1T9Q A;  2K2D A;  1R9T L;  1TWG L;  3GTK L;  1NXE A;  1SFO L;  1BFY A;  1PFY A;  5AN9 H;  3HJY B;  1ZRP A;  2ERJ A;  3H99 A;  4LHL A;  1Z92 B;  1VZI A;  4TVM A;  3HOV L;  3KYY A;  5MFP A;  2BE5 D;  1H7V A;  4WFN 1;  1E8J A;  1YK4 A;  1B71 A;  1TWA L;  2QL0 A;  2PYA A;  5H1S c;  3B08 B;  4A3F L;  2E2H L;  4A3B L;  3S1N L;  5FLM L;  2NVX L;  2JA7 L;  3I4M L;  7RXN A;  3NFP I;  2HVY C;  4YWL A;  4AR6 A;  2A69 D;  5MF6 A;  3S16 L;  3PIO 1;  1RWD A;  2KKD A;  5IYB L;  2JI1 A;  4XGH A;  2B5I D;  1I6H L;  1CAA A;  5JVH 1;  3S1M L;  2R92 L;  4XXB B;  2ERS A;  3K35 A;  2JI3 A;  2RDV A;  1VCX A;  1RYQ A;  2CR8 A;  4RXN A;  4TPU A;  3LWR B;  1IW7 D;  3KYX A;  1PFV A;  4AR5 A;  3PWF A;  3FDJ A;  4A3M L;  3H9C A;  1BQ8 A;  1B13 A;  3WWN B;  3GTL L;  1RYT A;  4C3H L;  2XJV A;  3B0A B;  3KYW A;  1S24 A;  1IRO A;  1VZH A;  3LNL A;  2L0Z A;  2DSX A;  3KYU A;  5M5X L;  3HKZ P;  5JVG 1;  2H12 A;  2XJR A;  4B8C D;  2EY4 E;  5MFZ A;  3I4N L;  2NYD A;  4AI3 A;  4E6Y A;  4BBS L;  1LTL A;  1F4L A;  1TWC L;  4JAF A;  2WAQ P;  4U67 1;  2XJP A;  3M4O L;  5M5Y L;  1Y1W L;  3ZG6 A;  1YUZ A;  1TWH L;  1PFW A;  1YV1 A;  1DVB A;  5IY0 A;  4AHZ A;  3S15 L;  3JR7 A;  1OWC A;  2R7Z L;  4POF A;  4AI1 A;  2V0E A;  3MPS A;  1B2J A;  3M3Y L;  5IYD L;  2M6O A;  4POG A;  1R0J A;  5IYC L;  5C4X L;  3GTG L;  1K83 L;  2XJU A;  1BE7 A;  2C6B A;  3PO3 L;  3FKI L;  2WB1 P;  4AHX A;  3RZO L;  1WCM L;  1B2O A;  2Y0S P;  4A3J L;  2E2I L;  2NVQ L;  4JAG A;  3K7A L;  5M3F L;  3S17 L;  2HR5 A;  3PIP 1;  2M6P A;  4AI2 A;  3HOZ L;  1BQ9 A;  3LWQ B;  2AYJ A;  4ME3 A;  1IU6 A;  3SS2 A;  2JA5 L;  2CKC A;  5GAH c;  1YUX A;  4LHN A;  4C3I L;  3H97 A;  6RXN A;  1IU5 A;  2AUS B;  3WWL A;  2A6E D;  2RFK B;  1RDG A;  3VPB E;  2A68 D;  4ZN1 B;  3P2A A;  2LCQ A;  4A3E L;  1SMM A;  1BRF A;  4Y7N L;  3IU3 I;  4X6A L;  4A3K L;  1R0G A;  2C6A A;  2PVE A;  3PZA A;  5M3M L;  5IP9 L;  4AYB P;  4YWM A;  1PFU A;  4AR3 A;  1S30 A;  3CQZ L;  2O5J D;  5C4J L;  5AI3 A;  5IP7 L;  2CKA A;  1S2Z A;  1LKO A;  3H9B A;  1PZX A;  4GS7 D;  3QQC E;  8RXN A;  2PVX A;  3HOX L;  2B63 L;  3S1Q L;  2J9U B;  2A6H D;  4AHY A;  3PO2 L;  3J7Z 1;  2Z3Q B;  3LWV B;  4C2M 1;  5M5W L;  4BBR L;  3A44 A;  1RB9 A;  3GTM L;  1WJV A;  5DM7 1;  3KYV A;  2NVY L;  4A93 L;  3LWP B;  4G6B A;  5K2M E;  1RDV A;  4BY1 L;  4BXX L;  5EIO C;  1DX8 A;  4A3I L;  2JI2 A;  1I3Q L;  3LPE B;  3H0G L;  2NVT L;  2R93 L;  4Y52 L;  2JA8 L;  3H3V M;  1R0I A;  1R0F A;  4A3L L;  3RZT A;  3PL5 A;  2GMG A;  2AQC A;  4UY8 1;  5EIN C;  3LWO B;  3J7Y 1;  1LKM A;  1LKP A;  1ODH A;  2VL6 A;  3HOY L;  2PSM C;  3S2H L;  2JA6 L;  1FHM A;  3HOW L;  4AHW A;  1CAD A;  1NXG A;  1NNQ A;  1YK5 A;  3RZD L;  3S14 L;  2XJT A;  3S2D L;  4K9F A;  3HAX C;  3HOU L;  2APO B;  5C44 L;  4JAE A;  2VUM L;  3PKJ A;  5GAE c;  4BY7 L;  1SMW A;  2ZIX A;  2M4Y A;  3GTO L;  3MQK B;  1FHH A;  3GTP L;  1P7P A;  3P8B A;  3HJW B;  5FJ8 L;  3PKI A;  4AR4 A;  4C3J L;  4AI0 A;  4QIW P;  2KN9 A;  4ZN3 B;  2XJQ A;  1QYB A;  1C09 A;  1JYB A;  5DM6 1;  2V3B B;  1T9P A; 
#chains in the Genus database with same CATH homology
 5M3F L;  3S17 L;  3S1M L;  3GTM L;  1I50 L;  2R92 L;  5C3E L;  2NVY L;  4BBR L;  3GTQ L;  4A93 L;  3HOZ L;  4BY1 L;  4BXX L;  1Y1V L;  4A3M L;  3GTJ L;  4A3I L;  1I3Q L;  2E2J L;  2JA5 L;  2YU9 L;  3GTL L;  4A3D L;  4C3I L;  3H0G L;  2NVT L;  4C3H L;  2R93 L;  4Y52 L;  2JA8 L;  1TWF L;  3H3V M;  2PMZ P;  4A3L L;  4A3G L;  3S1R L;  4A3C L;  5M5X L;  3HKZ P;  1R9T L;  1TWG L;  3GTK L;  3HOY L;  3S2H L;  1SFO L;  2JA6 L;  4A3E L;  3HOW L;  3I4N L;  4Y7N L;  4X6A L;  4A3K L;  3RZD L;  4BBS L;  3HOV L;  3S14 L;  3S2D L;  3HOU L;  5M3M L;  1TWC L;  2WAQ P;  3M4O L;  5C44 L;  5M5Y L;  5IP9 L;  1Y1W L;  1TWH L;  4AYB P;  2VUM L;  3S15 L;  2R7Z L;  3CQZ L;  5C4J L;  4BY7 L;  1TWA L;  3M3Y L;  3GTO L;  5IP7 L;  5IYD L;  3GTP L;  5IYC L;  2E2H L;  4A3F L;  4A3B L;  3S1N L;  5FLM L;  5FJ8 L;  5C4X L;  2NVX L;  3GTG L;  2JA7 L;  1K83 L;  4C3J L;  3I4M L;  4QIW P;  3HOX L;  2B63 L;  3S1Q L;  3PO3 L;  3FKI L;  2WB1 P;  3RZO L;  1WCM L;  3PO2 L;  2Y0S P;  4A3J L;  2E2I L;  3S16 L;  5IYB L;  2NVQ L;  4C2M 1;  5M5W L;  1I6H L;  3K7A L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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