1WCML

Complete 12-subunit rna polymerase ii at 3.8 angstrom
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Complete RNA Polymerase II and its Subcomplex,Rpb4/7
pubmed doi rcsb
molecule tags Transcription
source organism Saccharomyces cerevisiae
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2004-11-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 1wcmL00
3H0GL 5C3EL 5M3FL 3HOWL 3S2DL 4C3JL 2YU9L 4Y7NL 3PO2L 3HOYL 5M5XL 1Y1WL 3PO3L 3HKZP 4BXXL 3GTQL 2WAQP 4QIWP 5IYBL 2R92L 2E2IL 2JA7L 3GTML 2JA6L 1R9TL 2Y0SP 1SFOL 3S15L 3FKIL 3H3VM 3S17L 4C3IL 2E2HL 5M5WL 2PMZP 4C3HL 2VUML 4Y52L 3S16L 3HOZL 2R7ZL 3S1ML 4A3IL 3HOVL 1WCML 2JA5L 4A3EL 1I6HL 4A3KL 3RZOL 3S14L 4A3BL 2JA8L 4BBSL 2WB1P 3HOXL 2E2JL 5C44L 5C4JL 4X6AL 4BY7L 4AYBP 3S1NL 5C4XL 1K83L 5IP7L 3HOUL 1Y1VL 3M3YL 5FJ8L 1TWCL 2B63L 5IYCL 5M5YL 5IP9L 1I50L 3GTKL 2NVYL 3GTPL 3K7AL 3GTGL 2NVXL 3I4ML 4A3LL 3S1RL 4A3JL 3CQZL 1TWFL 1TWAL 5IYDL 4A3ML 3S2HL 4A3GL 1TWGL 2NVQL 3I4NL 3S1QL 3GTJL 3RZDL 2NVTL 4A3CL 1TWHL 5FLML 5M3ML 3GTOL 4BY1L 2R93L 3M4OL 4A3DL 1I3QL 4C2M1 4A3FL 4BBRL 3GTLL 4A93L
chains in the Genus database with same CATH superfamily
2ERJA 3ZG6A 3HJWB 4ZN3B 1BE7A 2A68D 1Y1WL 3K35A 4QIWP 1WJVA 2E2HL 3HJYB 2M4VA 2L0ZA 4Y52L 4JAGA 3P8BA 1S2ZA 1B71A 4XXBB 3LWOB 4AHYA 3VPBE 2XJQA 1PZXA 3HOVL 3B0AB 3LWRB 3RZOL 4BBSL 3HOXL 5C44L 5MGNA 4AR4A 4BY7L 2AUSB 1LTLA 1DVBA 2PPTA 3S1NL 3J7Y1 3M3YL 1BRFA 2Z3RB 2GMGA 4AR5A 1P7PA 1BQ9A 3H9BA 1FHMA 2HVYC 1T9QA 1LKOA 1RDVA 3JR7A 3RZTA 3KYYA 1E8JA 3GTGL 2NVXL 2KKDA 1TWFL 3PKIA 5IYDL 4AI0A 4ZN1B 1SMWA 1R0HA 1QQTA 2Z3QB 2R93L 1RYTA 4AHWA 5AI3A 8RXNA 1I3QL 3LNLA 4C2M1 6RXNA 4A93L 5M3FL 3KYXA 4C3JL 4Y7NL 3MSUA 2A69D 2C6AA 4YWLA 2PSMC 4AI2A 3MQKB 4BXXL 3GTQL 2XJUA 2E2IL 1ZRPA 2A6HD 2JA6L 1R9TL 1FHHA 3FKIL 1RDGA 1PFYA 3MPSA 3H3VM 4C3IL 3S17L 5IY0A 4C3HL 2VUML 3QQCE 3S16L 5EIOC 3HOZL 3S1ML 3WWLA 4A3IL 3LWQB 1DX8A 1VZGA 2CKCA 7RXNA 4JAFA 1BFYA 1WCML 3PKJA 4A3EL 2V0FA 2JI1A 4V196 4GS7D 5C4JL 1YV1A 3HAXC 4K9FA 5JVG1 3PIO1 4G6BA 5C4XL 3PWFA 2PVXA 2JI2A 5EINC 3HOUL 1Y1VL 2HR5A 2CKAA 1VCXA 5IYCL 5M5YL 2XJPA 3NFPI 4AI3A 3GTKL 1T9PA 3H9CA 1R0JA 1S24A 4A3LL 3S1RL 1LKMA 4A3JL 1TWAL 1R0GA 3B08B 4A3GL 3J7Z1 2NVQL 4AHXA 1CADA 3I4NL 3S1QL 3GTJL 1ODHA 3RZDL 3QVDA 3KYUA 3KYWA 2AYJA 5FLML 5M3ML 3GTOL 3PL5A 1H7VA 4A3FL 1SMUA 2KN9A 4BBRL 1YUXA 2XJRA 1IW7D 3LWVB 2O5JD 5C3EL 3S2DL 2YU9L 3PO2L 1SMMA 2PVEA 3PZAA 5M5XL 2XJVA 3PO3L 3HKZP 2BE5D 1B2JA 2R92L 3KYVA 2JA7L 2Y0SP 5GAEc 1SFOL 3S15L 5GAHc 4WFN1 3RZ6A 2APOB 2PMZP 1NXEA 2R7ZL 4TVMA 4POFA 4XGHA 3LPEB 5RXNA 1NXGA 2EY4E 2JA5L 4TPUA 2VL6A 3A44A 1I6HL 3S14L 2JA8L 2AQCA 2WB1P 1VZIA 4X6AL 2M4YA 3H99A 4B8CD 4AYBP 1NNQA 2DSXA 4LHNA 3SS2A 1K83L 1YK5A 1C09A 2ERSA 1QCVA 1TWCL 5FJ8L 4JAEA 2B63L 1I50L 2ZIXA 1PFUA 4AI1A 3GTPL 3I4ML 3IU3I 1Z92B 3CQZL 4AR3A 1RB9A 3P2AA 2J9UB 1OWCA 3S2HL 5AN9H 4YWMA 2K2DA 2MS3A 1PFVA 2XJTA 2RDVA 4A3CL 1IRNA 1B2OA 2JI3A 3PIP1 4A3DL 5MFZA 2M6OA 3GTLL 1IU6A 3WWNB 3H0GL 3HOWL 3HOYL 4ME3A 1BQ8A 2WAQP 1YUZA 5IYBL 3GTML 4UY81 4U671 3H97A 2LCQA 1LKPA 5MFPA 5M5WL 2C6BA 4JADA 5MLC3 1R0FA 3LWPB 1RWDA 2CR8A 1IROA 4A3KL 4A3BL 2QL0A 2E2JL 2PYAA 5K2ME 1T9OA 5AI2A 5IP7L 4E6YA 2M6PA 3FDJA 4POGA 4RXNA 1S30A 5IP9L 2B5ID 5H1Sc 1OWBA 2NVYL 5DM61 4AHZA 2H12A 3K7AL 5GADc 5JVH1 1B13A 1QYBA 2V0EA 1RYQA 1YK4A 4A3ML 5MF6A 1F4LA 2RFKB 1VZHA 1TWGL 2XJSA 1JYBA 2NVTL 1R0IA 1PFWA 4AR6A 5GAGc 1IU5A 1TWHL 2NYDA 4BY1L 1CAAA 3M4OL 2V3BB 5DM71 2A6ED 3RYGA 4LHLA
chains in the Genus database with same CATH topology
3H0GL 5C3EL 5M3FL 3HOWL 3S2DL 4C3JL 2YU9L 4Y7NL 3PO2L 3HOYL 5M5XL 1Y1WL 3PO3L 3HKZP 4BXXL 3GTQL 2WAQP 4QIWP 5IYBL 2R92L 2E2IL 2JA7L 3GTML 2JA6L 1R9TL 2Y0SP 1SFOL 3S15L 3FKIL 3H3VM 3S17L 4C3IL 2E2HL 5M5WL 2PMZP 4C3HL 2VUML 4Y52L 3S16L 3HOZL 2R7ZL 3S1ML 4A3IL 3HOVL 1WCML 2JA5L 4A3EL 1I6HL 4A3KL 3RZOL 3S14L 4A3BL 2JA8L 4BBSL 2WB1P 3HOXL 2E2JL 5C44L 5C4JL 4X6AL 4BY7L 4AYBP 3S1NL 5C4XL 1K83L 5IP7L 3HOUL 1Y1VL 3M3YL 5FJ8L 1TWCL 2B63L 5IYCL 5M5YL 5IP9L 1I50L 3GTKL 2NVYL 3GTPL 3K7AL 3GTGL 2NVXL 3I4ML 4A3LL 3S1RL 4A3JL 3CQZL 1TWFL 1TWAL 5IYDL 4A3ML 3S2HL 4A3GL 1TWGL 2NVQL 3I4NL 3S1QL 3GTJL 3RZDL 2NVTL 4A3CL 1TWHL 5FLML 5M3ML 3GTOL 4BY1L 2R93L 3M4OL 4A3DL 1I3QL 4C2M1 4A3FL 4BBRL 3GTLL 4A93L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H0G L;  5C3E L;  5M3F L;  3HOW L;  3S2D L;  4C3J L;  2YU9 L;  4Y7N L;  3PO2 L;  3HOY L;  5M5X L;  1Y1W L;  3PO3 L;  3HKZ P;  4BXX L;  3GTQ L;  2WAQ P;  4QIW P;  5IYB L;  2R92 L;  2E2I L;  2JA7 L;  3GTM L;  2JA6 L;  1R9T L;  2Y0S P;  1SFO L;  3S15 L;  3FKI L;  3H3V M;  3S17 L;  4C3I L;  2E2H L;  5M5W L;  2PMZ P;  4C3H L;  2VUM L;  4Y52 L;  3S16 L;  3HOZ L;  2R7Z L;  3S1M L;  4A3I L;  3HOV L;  1WCM L;  2JA5 L;  4A3E L;  1I6H L;  4A3K L;  3RZO L;  3S14 L;  4A3B L;  2JA8 L;  4BBS L;  2WB1 P;  3HOX L;  2E2J L;  5C44 L;  5C4J L;  4X6A L;  4BY7 L;  4AYB P;  3S1N L;  5C4X L;  1K83 L;  5IP7 L;  3HOU L;  1Y1V L;  3M3Y L;  5FJ8 L;  1TWC L;  2B63 L;  5IYC L;  5M5Y L;  5IP9 L;  1I50 L;  3GTK L;  2NVY L;  3GTP L;  3K7A L;  3GTG L;  2NVX L;  3I4M L;  4A3L L;  3S1R L;  4A3J L;  3CQZ L;  1TWF L;  1TWA L;  5IYD L;  4A3M L;  3S2H L;  4A3G L;  1TWG L;  2NVQ L;  3I4N L;  3S1Q L;  3GTJ L;  3RZD L;  2NVT L;  4A3C L;  1TWH L;  5FLM L;  5M3M L;  3GTO L;  4BY1 L;  2R93 L;  3M4O L;  4A3D L;  1I3Q L;  4C2M 1;  4A3F L;  4BBR L;  3GTL L;  4A93 L; 
#chains in the Genus database with same CATH topology
 2ERJ A;  3ZG6 A;  3HJW B;  4ZN3 B;  1BE7 A;  2A68 D;  1Y1W L;  3K35 A;  4QIW P;  1WJV A;  2E2H L;  3HJY B;  2M4V A;  2L0Z A;  4Y52 L;  4JAG A;  3P8B A;  1S2Z A;  1B71 A;  4XXB B;  3LWO B;  4AHY A;  3VPB E;  2XJQ A;  1PZX A;  3HOV L;  3B0A B;  3LWR B;  3RZO L;  4BBS L;  3HOX L;  5C44 L;  5MGN A;  4AR4 A;  4BY7 L;  2AUS B;  1LTL A;  1DVB A;  2PPT A;  3S1N L;  3J7Y 1;  3M3Y L;  1BRF A;  2Z3R B;  2GMG A;  4AR5 A;  1P7P A;  1BQ9 A;  3H9B A;  1FHM A;  2HVY C;  1T9Q A;  1LKO A;  1RDV A;  3JR7 A;  3RZT A;  3KYY A;  1E8J A;  3GTG L;  2NVX L;  2KKD A;  1TWF L;  3PKI A;  5IYD L;  4AI0 A;  4ZN1 B;  1SMW A;  1R0H A;  1QQT A;  2Z3Q B;  2R93 L;  1RYT A;  4AHW A;  5AI3 A;  8RXN A;  1I3Q L;  3LNL A;  4C2M 1;  6RXN A;  4A93 L;  5M3F L;  3KYX A;  4C3J L;  4Y7N L;  3MSU A;  2A69 D;  2C6A A;  4YWL A;  2PSM C;  4AI2 A;  3MQK B;  4BXX L;  3GTQ L;  2XJU A;  2E2I L;  1ZRP A;  2A6H D;  2JA6 L;  1R9T L;  1FHH A;  3FKI L;  1RDG A;  1PFY A;  3MPS A;  3H3V M;  4C3I L;  3S17 L;  5IY0 A;  4C3H L;  2VUM L;  3QQC E;  3S16 L;  5EIO C;  3HOZ L;  3S1M L;  3WWL A;  4A3I L;  3LWQ B;  1DX8 A;  1VZG A;  2CKC A;  7RXN A;  4JAF A;  1BFY A;  1WCM L;  3PKJ A;  4A3E L;  2V0F A;  2JI1 A;  4V19 6;  4GS7 D;  5C4J L;  1YV1 A;  3HAX C;  4K9F A;  5JVG 1;  3PIO 1;  4G6B A;  5C4X L;  3PWF A;  2PVX A;  2JI2 A;  5EIN C;  3HOU L;  1Y1V L;  2HR5 A;  2CKA A;  1VCX A;  5IYC L;  5M5Y L;  2XJP A;  3NFP I;  4AI3 A;  3GTK L;  1T9P A;  3H9C A;  1R0J A;  1S24 A;  4A3L L;  3S1R L;  1LKM A;  4A3J L;  1TWA L;  1R0G A;  3B08 B;  4A3G L;  3J7Z 1;  2NVQ L;  4AHX A;  1CAD A;  3I4N L;  3S1Q L;  3GTJ L;  1ODH A;  3RZD L;  3QVD A;  3KYU A;  3KYW A;  2AYJ A;  5FLM L;  5M3M L;  3GTO L;  3PL5 A;  1H7V A;  4A3F L;  1SMU A;  2KN9 A;  4BBR L;  1YUX A;  2XJR A;  1IW7 D;  3LWV B;  2O5J D;  5C3E L;  3S2D L;  2YU9 L;  3PO2 L;  1SMM A;  2PVE A;  3PZA A;  5M5X L;  2XJV A;  3PO3 L;  3HKZ P;  2BE5 D;  1B2J A;  2R92 L;  3KYV A;  2JA7 L;  2Y0S P;  5GAE c;  1SFO L;  3S15 L;  5GAH c;  4WFN 1;  3RZ6 A;  2APO B;  2PMZ P;  1NXE A;  2R7Z L;  4TVM A;  4POF A;  4XGH A;  3LPE B;  5RXN A;  1NXG A;  2EY4 E;  2JA5 L;  4TPU A;  2VL6 A;  3A44 A;  1I6H L;  3S14 L;  2JA8 L;  2AQC A;  2WB1 P;  1VZI A;  4X6A L;  2M4Y A;  3H99 A;  4B8C D;  4AYB P;  1NNQ A;  2DSX A;  4LHN A;  3SS2 A;  1K83 L;  1YK5 A;  1C09 A;  2ERS A;  1QCV A;  1TWC L;  5FJ8 L;  4JAE A;  2B63 L;  1I50 L;  2ZIX A;  1PFU A;  4AI1 A;  3GTP L;  3I4M L;  3IU3 I;  1Z92 B;  3CQZ L;  4AR3 A;  1RB9 A;  3P2A A;  2J9U B;  1OWC A;  3S2H L;  5AN9 H;  4YWM A;  2K2D A;  2MS3 A;  1PFV A;  2XJT A;  2RDV A;  4A3C L;  1IRN A;  1B2O A;  2JI3 A;  3PIP 1;  4A3D L;  5MFZ A;  2M6O A;  3GTL L;  1IU6 A;  3WWN B;  3H0G L;  3HOW L;  3HOY L;  4ME3 A;  1BQ8 A;  2WAQ P;  1YUZ A;  5IYB L;  3GTM L;  4UY8 1;  4U67 1;  3H97 A;  2LCQ A;  1LKP A;  5MFP A;  5M5W L;  2C6B A;  4JAD A;  5MLC 3;  1R0F A;  3LWP B;  1RWD A;  2CR8 A;  1IRO A;  4A3K L;  4A3B L;  2QL0 A;  2E2J L;  2PYA A;  5K2M E;  1T9O A;  5AI2 A;  5IP7 L;  4E6Y A;  2M6P A;  3FDJ A;  4POG A;  4RXN A;  1S30 A;  5IP9 L;  2B5I D;  5H1S c;  1OWB A;  2NVY L;  5DM6 1;  4AHZ A;  2H12 A;  3K7A L;  5GAD c;  5JVH 1;  1B13 A;  1QYB A;  2V0E A;  1RYQ A;  1YK4 A;  4A3M L;  5MF6 A;  1F4L A;  2RFK B;  1VZH A;  1TWG L;  2XJS A;  1JYB A;  2NVT L;  1R0I A;  1PFW A;  4AR6 A;  5GAG c;  1IU5 A;  1TWH L;  2NYD A;  4BY1 L;  1CAA A;  3M4O L;  2V3B B;  5DM7 1;  2A6E D;  3RYG A;  4LHL A; 
#chains in the Genus database with same CATH homology
 3H0G L;  5C3E L;  5M3F L;  3HOW L;  3S2D L;  4C3J L;  2YU9 L;  4Y7N L;  3PO2 L;  3HOY L;  5M5X L;  1Y1W L;  3PO3 L;  3HKZ P;  4BXX L;  3GTQ L;  2WAQ P;  4QIW P;  5IYB L;  2R92 L;  2E2I L;  2JA7 L;  3GTM L;  2JA6 L;  1R9T L;  2Y0S P;  1SFO L;  3S15 L;  3FKI L;  3H3V M;  3S17 L;  4C3I L;  2E2H L;  5M5W L;  2PMZ P;  4C3H L;  2VUM L;  4Y52 L;  3S16 L;  3HOZ L;  2R7Z L;  3S1M L;  4A3I L;  3HOV L;  1WCM L;  2JA5 L;  4A3E L;  1I6H L;  4A3K L;  3RZO L;  3S14 L;  4A3B L;  2JA8 L;  4BBS L;  2WB1 P;  3HOX L;  2E2J L;  5C44 L;  5C4J L;  4X6A L;  4BY7 L;  4AYB P;  3S1N L;  5C4X L;  1K83 L;  5IP7 L;  3HOU L;  1Y1V L;  3M3Y L;  5FJ8 L;  1TWC L;  2B63 L;  5IYC L;  5M5Y L;  5IP9 L;  1I50 L;  3GTK L;  2NVY L;  3GTP L;  3K7A L;  3GTG L;  2NVX L;  3I4M L;  4A3L L;  3S1R L;  4A3J L;  3CQZ L;  1TWF L;  1TWA L;  5IYD L;  4A3M L;  3S2H L;  4A3G L;  1TWG L;  2NVQ L;  3I4N L;  3S1Q L;  3GTJ L;  3RZD L;  2NVT L;  4A3C L;  1TWH L;  5FLM L;  5M3M L;  3GTO L;  4BY1 L;  2R93 L;  3M4O L;  4A3D L;  1I3Q L;  4C2M 1;  4A3F L;  4BBR L;  3GTL L;  4A93 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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