1FJMA

Protein serine/threonine phosphatase-1 (alpha isoform, type 1) complexed with microcystin-lr toxin
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
294
structure length
294
Chain Sequence
LNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords PROTEIN SERINE/THREONINE PHOSPHATASE-1 (ALPHA ISOFORM, TYPE
total genus 105
structure length 294
sequence length 294
chains with identical sequence B
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 1995-12-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 1fjmA00
4G9JA 3IB8A 4M0VA 5HPEA 4WWLA 1G5BA 4O4KA 5J28A 4F0ZA 4FBKA 1WAO1 3TGHA 4MOVA 1OIDA 3RL4A 2Z1AA 4UWQA 2Q8UA 2Z06A 4MOYA 1USHA 2WDDA 4JA9A 4FBWA 2BDXA 3PSOA 4B2OA 1Z2XA 2XMOA 1KBPA 3QFOA 2HY1A 5B8IA 3EGGA 5DNYA 3QG5C 3QFNA 3IVEA 2Z72A 2YVTA 3C9FA 4I5LC 2A22A 5GTUA 3DSDA 1S3MA 3THNA 3DSCA 2NPPC 3GVEA 4H1SA 2BQ8X 3IVDA 4TUGA 4UT3B 1XM7A 2BCDA 2P6BA 3E7AA 4H2FA 2NYMC 4ZX2A 4IYPC 1OI8A 1UF3A 1OIEA 4IL1A 3H67A 3JYFA 2JOGA 4YKEA 4O43A 4LTYA 4MP0A 3ZU0A 3ICFA 2KKNA 4UT2A 3AUZA 4DT2A 5IOHA 2IE4C 5JPFA 3FGAC 4J6OA 3P71C 2QFRA 1S3NA 3PSNA 3RQZA 2ZBMA 1IT6A 1QFCA 3K7WC 4XPNA 4OR9A 1V73A 1WARA 4UT3A 1AUIA 3H60A 2IE3C 1XZWA 2O8AA 4ORBA 1II7A 4TUIA 1NNWA 4Q7FA 2NYLC 5INBA 3N5UA 1HO5A 4V0VA 1SU1A 4KBPA 4V0XA 2WDCA 1HPUA 2GJUA 3T1IA 3QFKA 3K7VC 5JPEA 4LACC 4O5GA 4HD0A 3EGHA 4JA7A 3H69A 2WDFA 2HYPA 3ZTVA 3H64A 1S70A 1QHWA 3KBPA 3LL8A 4H2IA 3THOB 4KKZA 2USHA 3AV0A 3V4YA 4ORCA 1MF8A 5F3WA 3CK2A 2QFPA 4NZVA 1UTEA 4FBQA 2QJCA 3H68A 2NXFA 4ZVZA 1TCOA 3QFMA 4LU9A 1S8EA 1HP1A 1T71A 1M63A 2R17A 3H66A 4H2GA 2IAEC 3H61A 1T70A 3DW8C 3C5WC 4I5NC 5EQVA 3E7BA 2WDEA 2CV9A 3IB7A 4H2BA 4ORAA 4H1YP 2DFJA 4O24A 3RL5A 1S3LA 1FJMA 2HYOA 5C1VA 3HVQA 3H62B 1U32A 1W24A 1S95A 4FCXA 4V0WA 3RL3A 4DHLA 2AHDA 1JK7A 1Z2WA 5JJTA 3H63A 2O8GA 4DSYA
chains in the Genus database with same CATH superfamily
4G9JA 3IB8A 4M0VA 5HPEA 4WWLA 1G5BA 3FLOA 4O4KA 2ZO9B 4F0ZA 5J28A 4FBKA 1WAO1 3TGHA 4MOVA 1OIDA 3RL4A 2Z1AA 4UWQA 2Q8UA 2Z06A 4MOYA 1USHA 2WDDA 4JA9A 4FBWA 2BDXA 3PSOA 4B2OA 1Z2XA 2XMOA 1KBPA 3QFOA 2HY1A 5B8IA 3EGGA 5DNYA 3QG5C 3QFNA 3IVEA 2Z72A 2YVTA 3C9FA 4I5LC 3D03A 2A22A 3E0JA 5GTUA 3DSDA 1S3MA 3THNA 3DSCA 2NPPC 3GVEA 4H1SA 2BQ8X 3IVDA 4TUGA 4UT3B 1XM7A 2BCDA 2P6BA 3E7AA 4H2FA 2NYMC 4ZX2A 4IYPC 1OI8A 1UF3A 1OIEA 4IL1A 3H67A 3JYFA 2JOGA 4YKEA 2YEQA 4O43A 4LTYA 4MP0A 3ZU0A 3ICFA 2KKNA 4UT2A 3AUZA 4DT2A 5IOHA 2IE4C 5JPFA 3FGAC 4J6OA 3P71C 2QFRA 1S3NA 3PSNA 3RQZA 2ZBMA 1IT6A 1QFCA 3K7WC 4XPNA 4OR9A 1V73A 1WARA 4UT3A 1AUIA 3H60A 2IE3C 1XZWA 2O8AA 4ORBA 1II7A 4TUIA 1NNWA 4Q7FA 2NYLC 5INBA 3N5UA 1HO5A 4V0VA 1SU1A 4KBPA 4V0XA 2WDCA 1HPUA 2GJUA 3T1IA 3QFKA 2DXNA 3K7VC 5JPEA 4LACC 4O5GA 4HD0A 3EGHA 4JA7A 3H69A 2WDFA 2HYPA 3ZTVA 3H64A 1S70A 1QHWA 3KBPA 3LL8A 4H2IA 3THOB 4KKZA 2USHA 3AV0A 3V4YA 2ZOAA 4ORCA 1MF8A 5F3WA 3CK2A 2QFPA 4NZVA 1UTEA 4FBQA 2QJCA 3H68A 2NXFA 4ZVZA 1TCOA 3QFMA 4LU9A 1S8EA 1HP1A 1T71A 1M63A 2R17A 3H66A 4H2GA 2IAEC 3H61A 1T70A 3DW8C 3C5WC 4I5NC 5EQVA 3E7BA 2WDEA 2CV9A 3IB7A 4H2BA 4ORAA 4H1YP 2DFJA 4O24A 3RL5A 1S3LA 1FJMA 2HYOA 5C1VA 3HVQA 2DXLA 3H62B 1U32A 1W24A 1S95A 4FCXA 4V0WA 3RL3A 4DHLA 2AHDA 1JK7A 1Z2WA 5JJTA 3H63A 2O8GA 4DSYA
chains in the Genus database with same CATH topology
4G9JA 3IB8A 4M0VA 5HPEA 4WWLA 1G5BA 3FLOA 4O4KA 2ZO9B 4F0ZA 5J28A 4FBKA 1WAO1 3TGHA 4MOVA 1OIDA 3RL4A 2Z1AA 4UWQA 2Q8UA 2Z06A 4MOYA 1USHA 2WDDA 4JA9A 4FBWA 2BDXA 3PSOA 4B2OA 1Z2XA 2XMOA 1KBPA 3QFOA 2HY1A 5B8IA 3EGGA 5DNYA 3QG5C 3QFNA 3IVEA 2Z72A 2YVTA 3C9FA 4I5LC 3D03A 2A22A 3E0JA 5GTUA 3DSDA 1S3MA 3THNA 3DSCA 2NPPC 3GVEA 4H1SA 2BQ8X 3IVDA 4TUGA 4UT3B 1XM7A 2BCDA 2P6BA 3E7AA 4H2FA 2NYMC 4ZX2A 4IYPC 1OI8A 1UF3A 1OIEA 4IL1A 3H67A 3JYFA 2JOGA 4YKEA 2YEQA 4O43A 4LTYA 4MP0A 3ZU0A 3ICFA 2KKNA 4UT2A 3AUZA 4DT2A 5IOHA 2IE4C 5JPFA 3FGAC 4J6OA 3P71C 2QFRA 1S3NA 3PSNA 3RQZA 2ZBMA 1IT6A 1QFCA 3K7WC 4XPNA 4OR9A 1V73A 1WARA 4UT3A 1AUIA 3H60A 2IE3C 1XZWA 2O8AA 4ORBA 1II7A 4TUIA 1NNWA 4Q7FA 2NYLC 5INBA 3N5UA 1HO5A 4V0VA 1SU1A 4KBPA 4V0XA 2WDCA 1HPUA 2GJUA 3T1IA 3QFKA 2DXNA 3K7VC 5JPEA 4LACC 4O5GA 4HD0A 3EGHA 4JA7A 3H69A 2WDFA 2HYPA 3ZTVA 3H64A 1S70A 1QHWA 3KBPA 3LL8A 4H2IA 3THOB 4KKZA 2USHA 3AV0A 3V4YA 2ZOAA 4ORCA 1MF8A 5F3WA 3CK2A 2QFPA 4NZVA 1UTEA 4FBQA 2QJCA 3H68A 2NXFA 4ZVZA 1TCOA 3QFMA 4LU9A 1S8EA 1HP1A 1T71A 1M63A 2R17A 3H66A 4H2GA 2IAEC 3H61A 1T70A 3DW8C 3C5WC 4I5NC 5EQVA 3E7BA 2WDEA 2CV9A 3IB7A 4H2BA 4ORAA 4H1YP 2DFJA 4O24A 3RL5A 1S3LA 1FJMA 2HYOA 5C1VA 3HVQA 2DXLA 3H62B 1U32A 1W24A 1S95A 4FCXA 4V0WA 3RL3A 4DHLA 2AHDA 1JK7A 1Z2WA 5JJTA 3H63A 2O8GA 4DSYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G9J A;  3IB8 A;  4M0V A;  5HPE A;  4WWL A;  1G5B A;  4O4K A;  5J28 A;  4F0Z A;  4FBK A;  1WAO 1;  3TGH A;  4MOV A;  1OID A;  3RL4 A;  2Z1A A;  4UWQ A;  2Q8U A;  2Z06 A;  4MOY A;  1USH A;  2WDD A;  4JA9 A;  4FBW A;  2BDX A;  3PSO A;  4B2O A;  1Z2X A;  2XMO A;  1KBP A;  3QFO A;  2HY1 A;  5B8I A;  3EGG A;  5DNY A;  3QG5 C;  3QFN A;  3IVE A;  2Z72 A;  2YVT A;  3C9F A;  4I5L C;  2A22 A;  5GTU A;  3DSD A;  1S3M A;  3THN A;  3DSC A;  2NPP C;  3GVE A;  4H1S A;  2BQ8 X;  3IVD A;  4TUG A;  4UT3 B;  1XM7 A;  2BCD A;  2P6B A;  3E7A A;  4H2F A;  2NYM C;  4ZX2 A;  4IYP C;  1OI8 A;  1UF3 A;  1OIE A;  4IL1 A;  3H67 A;  3JYF A;  2JOG A;  4YKE A;  4O43 A;  4LTY A;  4MP0 A;  3ZU0 A;  3ICF A;  2KKN A;  4UT2 A;  3AUZ A;  4DT2 A;  5IOH A;  2IE4 C;  5JPF A;  3FGA C;  4J6O A;  3P71 C;  2QFR A;  1S3N A;  3PSN A;  3RQZ A;  2ZBM A;  1IT6 A;  1QFC A;  3K7W C;  4XPN A;  4OR9 A;  1V73 A;  1WAR A;  4UT3 A;  1AUI A;  3H60 A;  2IE3 C;  1XZW A;  2O8A A;  4ORB A;  1II7 A;  4TUI A;  1NNW A;  4Q7F A;  2NYL C;  5INB A;  3N5U A;  1HO5 A;  4V0V A;  1SU1 A;  4KBP A;  4V0X A;  2WDC A;  1HPU A;  2GJU A;  3T1I A;  3QFK A;  3K7V C;  5JPE A;  4LAC C;  4O5G A;  4HD0 A;  3EGH A;  4JA7 A;  3H69 A;  2WDF A;  2HYP A;  3ZTV A;  3H64 A;  1S70 A;  1QHW A;  3KBP A;  3LL8 A;  4H2I A;  3THO B;  4KKZ A;  2USH A;  3AV0 A;  3V4Y A;  4ORC A;  1MF8 A;  5F3W A;  3CK2 A;  2QFP A;  4NZV A;  1UTE A;  4FBQ A;  2QJC A;  3H68 A;  2NXF A;  4ZVZ A;  1TCO A;  3QFM A;  4LU9 A;  1S8E A;  1HP1 A;  1T71 A;  1M63 A;  2R17 A;  3H66 A;  4H2G A;  2IAE C;  3H61 A;  1T70 A;  3DW8 C;  3C5W C;  4I5N C;  5EQV A;  3E7B A;  2WDE A;  2CV9 A;  3IB7 A;  4H2B A;  4ORA A;  4H1Y P;  2DFJ A;  4O24 A;  3RL5 A;  1S3L A;  1FJM A;  2HYO A;  5C1V A;  3HVQ A;  3H62 B;  1U32 A;  1W24 A;  1S95 A;  4FCX A;  4V0W A;  3RL3 A;  4DHL A;  2AHD A;  1JK7 A;  1Z2W A;  5JJT A;  3H63 A;  2O8G A;  4DSY A; 
#chains in the Genus database with same CATH topology
 4G9J A;  3IB8 A;  4M0V A;  5HPE A;  4WWL A;  1G5B A;  3FLO A;  4O4K A;  2ZO9 B;  4F0Z A;  5J28 A;  4FBK A;  1WAO 1;  3TGH A;  4MOV A;  1OID A;  3RL4 A;  2Z1A A;  4UWQ A;  2Q8U A;  2Z06 A;  4MOY A;  1USH A;  2WDD A;  4JA9 A;  4FBW A;  2BDX A;  3PSO A;  4B2O A;  1Z2X A;  2XMO A;  1KBP A;  3QFO A;  2HY1 A;  5B8I A;  3EGG A;  5DNY A;  3QG5 C;  3QFN A;  3IVE A;  2Z72 A;  2YVT A;  3C9F A;  4I5L C;  3D03 A;  2A22 A;  3E0J A;  5GTU A;  3DSD A;  1S3M A;  3THN A;  3DSC A;  2NPP C;  3GVE A;  4H1S A;  2BQ8 X;  3IVD A;  4TUG A;  4UT3 B;  1XM7 A;  2BCD A;  2P6B A;  3E7A A;  4H2F A;  2NYM C;  4ZX2 A;  4IYP C;  1OI8 A;  1UF3 A;  1OIE A;  4IL1 A;  3H67 A;  3JYF A;  2JOG A;  4YKE A;  2YEQ A;  4O43 A;  4LTY A;  4MP0 A;  3ZU0 A;  3ICF A;  2KKN A;  4UT2 A;  3AUZ A;  4DT2 A;  5IOH A;  2IE4 C;  5JPF A;  3FGA C;  4J6O A;  3P71 C;  2QFR A;  1S3N A;  3PSN A;  3RQZ A;  2ZBM A;  1IT6 A;  1QFC A;  3K7W C;  4XPN A;  4OR9 A;  1V73 A;  1WAR A;  4UT3 A;  1AUI A;  3H60 A;  2IE3 C;  1XZW A;  2O8A A;  4ORB A;  1II7 A;  4TUI A;  1NNW A;  4Q7F A;  2NYL C;  5INB A;  3N5U A;  1HO5 A;  4V0V A;  1SU1 A;  4KBP A;  4V0X A;  2WDC A;  1HPU A;  2GJU A;  3T1I A;  3QFK A;  2DXN A;  3K7V C;  5JPE A;  4LAC C;  4O5G A;  4HD0 A;  3EGH A;  4JA7 A;  3H69 A;  2WDF A;  2HYP A;  3ZTV A;  3H64 A;  1S70 A;  1QHW A;  3KBP A;  3LL8 A;  4H2I A;  3THO B;  4KKZ A;  2USH A;  3AV0 A;  3V4Y A;  2ZOA A;  4ORC A;  1MF8 A;  5F3W A;  3CK2 A;  2QFP A;  4NZV A;  1UTE A;  4FBQ A;  2QJC A;  3H68 A;  2NXF A;  4ZVZ A;  1TCO A;  3QFM A;  4LU9 A;  1S8E A;  1HP1 A;  1T71 A;  1M63 A;  2R17 A;  3H66 A;  4H2G A;  2IAE C;  3H61 A;  1T70 A;  3DW8 C;  3C5W C;  4I5N C;  5EQV A;  3E7B A;  2WDE A;  2CV9 A;  3IB7 A;  4H2B A;  4ORA A;  4H1Y P;  2DFJ A;  4O24 A;  3RL5 A;  1S3L A;  1FJM A;  2HYO A;  5C1V A;  3HVQ A;  2DXL A;  3H62 B;  1U32 A;  1W24 A;  1S95 A;  4FCX A;  4V0W A;  3RL3 A;  4DHL A;  2AHD A;  1JK7 A;  1Z2W A;  5JJT A;  3H63 A;  2O8G A;  4DSY A; 
#chains in the Genus database with same CATH homology
 4G9J A;  3IB8 A;  4M0V A;  5HPE A;  4WWL A;  1G5B A;  3FLO A;  4O4K A;  2ZO9 B;  4F0Z A;  5J28 A;  4FBK A;  1WAO 1;  3TGH A;  4MOV A;  1OID A;  3RL4 A;  2Z1A A;  4UWQ A;  2Q8U A;  2Z06 A;  4MOY A;  1USH A;  2WDD A;  4JA9 A;  4FBW A;  2BDX A;  3PSO A;  4B2O A;  1Z2X A;  2XMO A;  1KBP A;  3QFO A;  2HY1 A;  5B8I A;  3EGG A;  5DNY A;  3QG5 C;  3QFN A;  3IVE A;  2Z72 A;  2YVT A;  3C9F A;  4I5L C;  3D03 A;  2A22 A;  3E0J A;  5GTU A;  3DSD A;  1S3M A;  3THN A;  3DSC A;  2NPP C;  3GVE A;  4H1S A;  2BQ8 X;  3IVD A;  4TUG A;  4UT3 B;  1XM7 A;  2BCD A;  2P6B A;  3E7A A;  4H2F A;  2NYM C;  4ZX2 A;  4IYP C;  1OI8 A;  1UF3 A;  1OIE A;  4IL1 A;  3H67 A;  3JYF A;  2JOG A;  4YKE A;  2YEQ A;  4O43 A;  4LTY A;  4MP0 A;  3ZU0 A;  3ICF A;  2KKN A;  4UT2 A;  3AUZ A;  4DT2 A;  5IOH A;  2IE4 C;  5JPF A;  3FGA C;  4J6O A;  3P71 C;  2QFR A;  1S3N A;  3PSN A;  3RQZ A;  2ZBM A;  1IT6 A;  1QFC A;  3K7W C;  4XPN A;  4OR9 A;  1V73 A;  1WAR A;  4UT3 A;  1AUI A;  3H60 A;  2IE3 C;  1XZW A;  2O8A A;  4ORB A;  1II7 A;  4TUI A;  1NNW A;  4Q7F A;  2NYL C;  5INB A;  3N5U A;  1HO5 A;  4V0V A;  1SU1 A;  4KBP A;  4V0X A;  2WDC A;  1HPU A;  2GJU A;  3T1I A;  3QFK A;  2DXN A;  3K7V C;  5JPE A;  4LAC C;  4O5G A;  4HD0 A;  3EGH A;  4JA7 A;  3H69 A;  2WDF A;  2HYP A;  3ZTV A;  3H64 A;  1S70 A;  1QHW A;  3KBP A;  3LL8 A;  4H2I A;  3THO B;  4KKZ A;  2USH A;  3AV0 A;  3V4Y A;  2ZOA A;  4ORC A;  1MF8 A;  5F3W A;  3CK2 A;  2QFP A;  4NZV A;  1UTE A;  4FBQ A;  2QJC A;  3H68 A;  2NXF A;  4ZVZ A;  1TCO A;  3QFM A;  4LU9 A;  1S8E A;  1HP1 A;  1T71 A;  1M63 A;  2R17 A;  3H66 A;  4H2G A;  2IAE C;  3H61 A;  1T70 A;  3DW8 C;  3C5W C;  4I5N C;  5EQV A;  3E7B A;  2WDE A;  2CV9 A;  3IB7 A;  4H2B A;  4ORA A;  4H1Y P;  2DFJ A;  4O24 A;  3RL5 A;  1S3L A;  1FJM A;  2HYO A;  5C1V A;  3HVQ A;  2DXL A;  3H62 B;  1U32 A;  1W24 A;  1S95 A;  4FCX A;  4V0W A;  3RL3 A;  4DHL A;  2AHD A;  1JK7 A;  1Z2W A;  5JJT A;  3H63 A;  2O8G A;  4DSY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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