1I50L

Rna polymerase ii crystal form ii at 2.8 a resolution
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2001-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 1i50L00
3PO3L 1SFOL 3HOWL 3S2HL 4A3JL 5M5YL 1TWAL 3RZDL 3FKIL 1TWHL 2WAQP 3HOZL 4A3ML 3S14L 4BBRL 4A3FL 4C3JL 3GTKL 5M3ML 5IYCL 1I3QL 3S1QL 2YU9L 2JA7L 4C3IL 1Y1VL 3GTPL 4BBSL 3HOXL 4BXXL 4A3CL 2R93L 3S1RL 4A3EL 2WB1P 3H0GL 2JA8L 4A3DL 1I6HL 3S1ML 3HKZP 5M3FL 4A3KL 2NVTL 3S15L 3GTOL 2JA6L 5M5WL 2Y0SP 2NVXL 5C4JL 4Y7NL 4A3BL 1R9TL 3GTGL 3HOUL 4A3GL 3PO2L 1Y1WL 3H3VM 3CQZL 4X6AL 2B63L 4Y52L 4A3IL 3S2DL 3M3YL 3RZOL 5C44L 3S1NL 2R7ZL 4AYBP 5M5XL 3I4ML 1TWFL 3M4OL 3HOYL 3K7AL 4C2M1 5IP9L 5C4XL 3GTJL 2JA5L 5FLML 1TWGL 3S16L 4BY1L 2NVYL 3GTQL 5IP7L 2VUML 3I4NL 1TWCL 5C3EL 4QIWP 4A3LL 2R92L 1K83L 2PMZP 3GTLL 3GTML 1I50L 5FJ8L 2NVQL 5IYDL 3S17L 4C3HL 3HOVL 2E2JL 2E2IL 1WCML 2E2HL 4A93L 5IYBL 4BY7L
chains in the Genus database with same CATH superfamily
2HR5A 2XJTA 2ZIXA 1TWAL 2O5JD 5RXNA 5AI3A 8RXNA 2A6ED 4C3JL 3GTKL 1RWDA 1ZRPA 5GAGc 1IW7D 2H12A 1B2OA 6RXNA 3GTPL 4BBSL 5MFPA 1FHHA 1YUXA 2PVEA 4LHNA 3B0AB 5JVG1 3S1RL 2R93L 2WB1P 4ZN3B 1T9QA 2LCQA 1FHMA 1I6HL 4YWMA 4A3KL 1PFYA 5AI2A 2JA6L 1VZIA 3LNLA 2K2DA 4A3GL 3PO2L 4X6AL 3PWFA 2B63L 5H1Sc 4K9FA 3PZAA 4A3IL 3KYVA 3S2DL 1S30A 1VCXA 5MGNA 4AI1A 4POGA 3S1NL 4AHYA 4AYBP 2PYAA 3ZG6A 3I4ML 5GAEc 1YUZA 4TPUA 2VL6A 2DSXA 4AI2A 4AR4A 2RDVA 4C2M1 2JI2A 3GTJL 4V196 1R0FA 5FLML 1TWGL 2V0EA 1RYQA 1C09A 2XJRA 1RB9A 3QQCE 3HAXC 1BRFA 1IRNA 4QIWP 3MSUA 1VZGA 2R92L 3WWLA 1LKMA 3GTLL 2XJSA 2V0FA 2EY4E 5IYDL 2J9UB 2E2HL 4A93L 5M5YL 1TWHL 5AN9H 3KYYA 5MLC3 4AHZA 4A3FL 1LTLA 2XJUA 4JAFA 4E6YA 1PZXA 1BE7A 2B5ID 1NNQA 2PVXA 1NXGA 1Z92B 4BXXL 3HJYB 4ME3A 3P2AA 2KN9A 5JVH1 3S1ML 1RDGA 3B08B 1S24A 3S15L 1R0HA 5M5WL 2Y0SP 3LWQB 1R9TL 3KYXA 3PIP1 1PFVA 2M6OA 3KYUA 2MS3A 1CAAA 4POFA 2A69D 1T9PA 2V3BB 3LWPB 5M5XL 1TWFL 5EINC 5DM61 3M4OL 1QCVA 3K35A 2KKDA 1CADA 2JA5L 4RXNA 3PIO1 1DVBA 2QL0A 3GTQL 5IP7L 4AI3A 4A3LL 1JYBA 2PMZP 1IU6A 1I50L 1S2ZA 1R0JA 2A6HD 3HOVL 2E2JL 2AYJA 1WCML 3LWOB 5IYBL 2XJPA 5MFZA 2M4YA 4BY7L 1SFOL 1E8JA 3S2HL 4A3JL 2XJQA 2Z3RB 4A3ML 3S14L 4AHXA 2YU9L 2JA7L 4C3IL 3QVDA 4AI0A 3HOXL 2AQCA 1R0IA 3J7Z1 4A3CL 1WJVA 3H0GL 1PFUA 4A3DL 2C6BA 3HKZP 2BE5D 2L0ZA 4B8CD 3GTOL 2AUSB 4ZN1B 2NVXL 5C4JL 3MPSA 3PKIA 4A3BL 1YV1A 4U671 3GTGL 3LPEB 1Y1WL 2XJVA 2ERJA 4Y52L 3M3YL 3SS2A 1NXEA 4AR6A 3RZOL 5EIOC 2R7ZL 4GS7D 3PL5A 1BQ9A 3RYGA 3H99A 4JAGA 3HOYL 1OWBA 3H9BA 3K7AL 1SMMA 2NVYL 4LHLA 2C6AA 1TWCL 5GADc 2PPTA 2M6PA 1B71A 5GAHc 3RZTA 1SMUA 3A44A 1BQ8A 3NFPI 3P8BA 1IU5A 4C3HL 1QQTA 4JADA 3LWVB 2E2IL 2A68D 3JR7A 5DM71 3H9CA 4YWLA 3PO3L 3HOWL 4G6BA 1PFWA 2APOB 1T9OA 3RZDL 3FKIL 4JAEA 4UY81 2WAQP 1H7VA 3HOZL 1RDVA 4AR5A 4BBRL 5M3ML 5IYCL 1I3QL 2CKAA 3S1QL 2JI1A 1Y1VL 2Z3QB 1VZHA 7RXNA 4A3EL 3RZ6A 4AR3A 2RFKB 2JA8L 1ODHA 5M3FL 1P7PA 2NVTL 1LKOA 1F4LA 1YK4A 3VPBE 3PKJA 1SMWA 4Y7NL 2CR8A 3HOUL 3IU3I 3H3VM 3CQZL 4XGHA 4AHWA 4TVMA 1QYBA 3H97A 1DX8A 2HVYC 5C44L 1RYTA 4XXBB 1OWCA 1B13A 2JI3A 5C4XL 2NYDA 5IP9L 2ERSA 5MF6A 3S16L 1R0GA 3WWNB 4BY1L 3HJWB 2VUML 5IY0A 3I4NL 1B2JA 5C3EL 3KYWA 3MQKB 2CKCA 1K83L 3LWRB 3GTML 2GMGA 5FJ8L 2NVQL 2M4VA 1LKPA 3S17L 4WFN1 1IROA 5K2ME 3FDJA 1YK5A 2PSMC 3J7Y1 1BFYA
chains in the Genus database with same CATH topology
3PO3L 1SFOL 3HOWL 3S2HL 4A3JL 5M5YL 1TWAL 3RZDL 3FKIL 1TWHL 2WAQP 3HOZL 4A3ML 3S14L 4BBRL 4A3FL 4C3JL 3GTKL 5M3ML 5IYCL 1I3QL 3S1QL 2YU9L 2JA7L 4C3IL 1Y1VL 3GTPL 4BBSL 3HOXL 4BXXL 4A3CL 2R93L 3S1RL 4A3EL 2WB1P 3H0GL 2JA8L 4A3DL 1I6HL 3S1ML 3HKZP 5M3FL 4A3KL 2NVTL 3S15L 3GTOL 2JA6L 5M5WL 2Y0SP 2NVXL 5C4JL 4Y7NL 4A3BL 1R9TL 3GTGL 3HOUL 4A3GL 3PO2L 1Y1WL 3H3VM 3CQZL 4X6AL 2B63L 4Y52L 4A3IL 3S2DL 3M3YL 3RZOL 5C44L 3S1NL 2R7ZL 4AYBP 5M5XL 3I4ML 1TWFL 3M4OL 3HOYL 3K7AL 4C2M1 5IP9L 5C4XL 3GTJL 2JA5L 5FLML 1TWGL 3S16L 4BY1L 2NVYL 3GTQL 5IP7L 2VUML 3I4NL 1TWCL 5C3EL 4QIWP 4A3LL 2R92L 1K83L 2PMZP 3GTLL 3GTML 1I50L 5FJ8L 2NVQL 5IYDL 3S17L 4C3HL 3HOVL 2E2JL 2E2IL 1WCML 2E2HL 4A93L 5IYBL 4BY7L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PO3 L;  1SFO L;  3HOW L;  3S2H L;  4A3J L;  5M5Y L;  1TWA L;  3RZD L;  3FKI L;  1TWH L;  2WAQ P;  3HOZ L;  4A3M L;  3S14 L;  4BBR L;  4A3F L;  4C3J L;  3GTK L;  5M3M L;  5IYC L;  1I3Q L;  3S1Q L;  2YU9 L;  2JA7 L;  4C3I L;  1Y1V L;  3GTP L;  4BBS L;  3HOX L;  4BXX L;  4A3C L;  2R93 L;  3S1R L;  4A3E L;  2WB1 P;  3H0G L;  2JA8 L;  4A3D L;  1I6H L;  3S1M L;  3HKZ P;  5M3F L;  4A3K L;  2NVT L;  3S15 L;  3GTO L;  2JA6 L;  5M5W L;  2Y0S P;  2NVX L;  5C4J L;  4Y7N L;  4A3B L;  1R9T L;  3GTG L;  3HOU L;  4A3G L;  3PO2 L;  1Y1W L;  3H3V M;  3CQZ L;  4X6A L;  2B63 L;  4Y52 L;  4A3I L;  3S2D L;  3M3Y L;  3RZO L;  5C44 L;  3S1N L;  2R7Z L;  4AYB P;  5M5X L;  3I4M L;  1TWF L;  3M4O L;  3HOY L;  3K7A L;  4C2M 1;  5IP9 L;  5C4X L;  3GTJ L;  2JA5 L;  5FLM L;  1TWG L;  3S16 L;  4BY1 L;  2NVY L;  3GTQ L;  5IP7 L;  2VUM L;  3I4N L;  1TWC L;  5C3E L;  4QIW P;  4A3L L;  2R92 L;  1K83 L;  2PMZ P;  3GTL L;  3GTM L;  1I50 L;  5FJ8 L;  2NVQ L;  5IYD L;  3S17 L;  4C3H L;  3HOV L;  2E2J L;  2E2I L;  1WCM L;  2E2H L;  4A93 L;  5IYB L;  4BY7 L; 
#chains in the Genus database with same CATH topology
 2HR5 A;  2XJT A;  2ZIX A;  1TWA L;  2O5J D;  5RXN A;  5AI3 A;  8RXN A;  2A6E D;  4C3J L;  3GTK L;  1RWD A;  1ZRP A;  5GAG c;  1IW7 D;  2H12 A;  1B2O A;  6RXN A;  3GTP L;  4BBS L;  5MFP A;  1FHH A;  1YUX A;  2PVE A;  4LHN A;  3B0A B;  5JVG 1;  3S1R L;  2R93 L;  2WB1 P;  4ZN3 B;  1T9Q A;  2LCQ A;  1FHM A;  1I6H L;  4YWM A;  4A3K L;  1PFY A;  5AI2 A;  2JA6 L;  1VZI A;  3LNL A;  2K2D A;  4A3G L;  3PO2 L;  4X6A L;  3PWF A;  2B63 L;  5H1S c;  4K9F A;  3PZA A;  4A3I L;  3KYV A;  3S2D L;  1S30 A;  1VCX A;  5MGN A;  4AI1 A;  4POG A;  3S1N L;  4AHY A;  4AYB P;  2PYA A;  3ZG6 A;  3I4M L;  5GAE c;  1YUZ A;  4TPU A;  2VL6 A;  2DSX A;  4AI2 A;  4AR4 A;  2RDV A;  4C2M 1;  2JI2 A;  3GTJ L;  4V19 6;  1R0F A;  5FLM L;  1TWG L;  2V0E A;  1RYQ A;  1C09 A;  2XJR A;  1RB9 A;  3QQC E;  3HAX C;  1BRF A;  1IRN A;  4QIW P;  3MSU A;  1VZG A;  2R92 L;  3WWL A;  1LKM A;  3GTL L;  2XJS A;  2V0F A;  2EY4 E;  5IYD L;  2J9U B;  2E2H L;  4A93 L;  5M5Y L;  1TWH L;  5AN9 H;  3KYY A;  5MLC 3;  4AHZ A;  4A3F L;  1LTL A;  2XJU A;  4JAF A;  4E6Y A;  1PZX A;  1BE7 A;  2B5I D;  1NNQ A;  2PVX A;  1NXG A;  1Z92 B;  4BXX L;  3HJY B;  4ME3 A;  3P2A A;  2KN9 A;  5JVH 1;  3S1M L;  1RDG A;  3B08 B;  1S24 A;  3S15 L;  1R0H A;  5M5W L;  2Y0S P;  3LWQ B;  1R9T L;  3KYX A;  3PIP 1;  1PFV A;  2M6O A;  3KYU A;  2MS3 A;  1CAA A;  4POF A;  2A69 D;  1T9P A;  2V3B B;  3LWP B;  5M5X L;  1TWF L;  5EIN C;  5DM6 1;  3M4O L;  1QCV A;  3K35 A;  2KKD A;  1CAD A;  2JA5 L;  4RXN A;  3PIO 1;  1DVB A;  2QL0 A;  3GTQ L;  5IP7 L;  4AI3 A;  4A3L L;  1JYB A;  2PMZ P;  1IU6 A;  1I50 L;  1S2Z A;  1R0J A;  2A6H D;  3HOV L;  2E2J L;  2AYJ A;  1WCM L;  3LWO B;  5IYB L;  2XJP A;  5MFZ A;  2M4Y A;  4BY7 L;  1SFO L;  1E8J A;  3S2H L;  4A3J L;  2XJQ A;  2Z3R B;  4A3M L;  3S14 L;  4AHX A;  2YU9 L;  2JA7 L;  4C3I L;  3QVD A;  4AI0 A;  3HOX L;  2AQC A;  1R0I A;  3J7Z 1;  4A3C L;  1WJV A;  3H0G L;  1PFU A;  4A3D L;  2C6B A;  3HKZ P;  2BE5 D;  2L0Z A;  4B8C D;  3GTO L;  2AUS B;  4ZN1 B;  2NVX L;  5C4J L;  3MPS A;  3PKI A;  4A3B L;  1YV1 A;  4U67 1;  3GTG L;  3LPE B;  1Y1W L;  2XJV A;  2ERJ A;  4Y52 L;  3M3Y L;  3SS2 A;  1NXE A;  4AR6 A;  3RZO L;  5EIO C;  2R7Z L;  4GS7 D;  3PL5 A;  1BQ9 A;  3RYG A;  3H99 A;  4JAG A;  3HOY L;  1OWB A;  3H9B A;  3K7A L;  1SMM A;  2NVY L;  4LHL A;  2C6A A;  1TWC L;  5GAD c;  2PPT A;  2M6P A;  1B71 A;  5GAH c;  3RZT A;  1SMU A;  3A44 A;  1BQ8 A;  3NFP I;  3P8B A;  1IU5 A;  4C3H L;  1QQT A;  4JAD A;  3LWV B;  2E2I L;  2A68 D;  3JR7 A;  5DM7 1;  3H9C A;  4YWL A;  3PO3 L;  3HOW L;  4G6B A;  1PFW A;  2APO B;  1T9O A;  3RZD L;  3FKI L;  4JAE A;  4UY8 1;  2WAQ P;  1H7V A;  3HOZ L;  1RDV A;  4AR5 A;  4BBR L;  5M3M L;  5IYC L;  1I3Q L;  2CKA A;  3S1Q L;  2JI1 A;  1Y1V L;  2Z3Q B;  1VZH A;  7RXN A;  4A3E L;  3RZ6 A;  4AR3 A;  2RFK B;  2JA8 L;  1ODH A;  5M3F L;  1P7P A;  2NVT L;  1LKO A;  1F4L A;  1YK4 A;  3VPB E;  3PKJ A;  1SMW A;  4Y7N L;  2CR8 A;  3HOU L;  3IU3 I;  3H3V M;  3CQZ L;  4XGH A;  4AHW A;  4TVM A;  1QYB A;  3H97 A;  1DX8 A;  2HVY C;  5C44 L;  1RYT A;  4XXB B;  1OWC A;  1B13 A;  2JI3 A;  5C4X L;  2NYD A;  5IP9 L;  2ERS A;  5MF6 A;  3S16 L;  1R0G A;  3WWN B;  4BY1 L;  3HJW B;  2VUM L;  5IY0 A;  3I4N L;  1B2J A;  5C3E L;  3KYW A;  3MQK B;  2CKC A;  1K83 L;  3LWR B;  3GTM L;  2GMG A;  5FJ8 L;  2NVQ L;  2M4V A;  1LKP A;  3S17 L;  4WFN 1;  1IRO A;  5K2M E;  3FDJ A;  1YK5 A;  2PSM C;  3J7Y 1;  1BFY A; 
#chains in the Genus database with same CATH homology
 3PO3 L;  1SFO L;  3HOW L;  3S2H L;  4A3J L;  5M5Y L;  1TWA L;  3RZD L;  3FKI L;  1TWH L;  2WAQ P;  3HOZ L;  4A3M L;  3S14 L;  4BBR L;  4A3F L;  4C3J L;  3GTK L;  5M3M L;  5IYC L;  1I3Q L;  3S1Q L;  2YU9 L;  2JA7 L;  4C3I L;  1Y1V L;  3GTP L;  4BBS L;  3HOX L;  4BXX L;  4A3C L;  2R93 L;  3S1R L;  4A3E L;  2WB1 P;  3H0G L;  2JA8 L;  4A3D L;  1I6H L;  3S1M L;  3HKZ P;  5M3F L;  4A3K L;  2NVT L;  3S15 L;  3GTO L;  2JA6 L;  5M5W L;  2Y0S P;  2NVX L;  5C4J L;  4Y7N L;  4A3B L;  1R9T L;  3GTG L;  3HOU L;  4A3G L;  3PO2 L;  1Y1W L;  3H3V M;  3CQZ L;  4X6A L;  2B63 L;  4Y52 L;  4A3I L;  3S2D L;  3M3Y L;  3RZO L;  5C44 L;  3S1N L;  2R7Z L;  4AYB P;  5M5X L;  3I4M L;  1TWF L;  3M4O L;  3HOY L;  3K7A L;  4C2M 1;  5IP9 L;  5C4X L;  3GTJ L;  2JA5 L;  5FLM L;  1TWG L;  3S16 L;  4BY1 L;  2NVY L;  3GTQ L;  5IP7 L;  2VUM L;  3I4N L;  1TWC L;  5C3E L;  4QIW P;  4A3L L;  2R92 L;  1K83 L;  2PMZ P;  3GTL L;  3GTM L;  1I50 L;  5FJ8 L;  2NVQ L;  5IYD L;  3S17 L;  4C3H L;  3HOV L;  2E2J L;  2E2I L;  1WCM L;  2E2H L;  4A93 L;  5IYB L;  4BY7 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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