1JK7A

Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
294
structure length
294
Chain Sequence
KLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1.
pubmed doi rcsb
molecule tags Hydrolase/toxin
source organism Homo sapiens
molecule keywords SERINE/THREONINE PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUB
total genus 105
structure length 294
sequence length 294
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2001-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 1jk7A00
5DNYA 4KKZA 2HYOA 3AUZA 4ZVZA 3ICFA 4FBQA 3AV0A 1HPUA 4Q7FA 1WARA 3IVEA 3H63A 2O8GA 2BQ8X 3IB8A 3E7BA 3FGAC 4MP0A 4LU9A 3H60A 2R17A 5EQVA 1AUIA 2Z06A 2QFPA 4HD0A 2O8AA 3HVQA 3QFOA 3IVDA 4DSYA 1IT6A 5B8IA 2HYPA 3KBPA 1OIDA 3C9FA 3H62B 3LL8A 4I5NC 4J6OA 4TUIA 4TUGA 3H66A 4G9JA 3DSDA 4FBWA 3GVEA 1S3MA 4B2OA 2IAEC 2WDCA 2HY1A 3K7VC 3H67A 1KBPA 4JA9A 2DFJA 5JPFA 3PSOA 1II7A 4H2GA 4MOYA 4O4KA 4IYPC 4UT3A 2Q8UA 4O43A 2IE4C 3QFMA 4UWQA 5JJTA 2QJCA 1S8EA 1W24A 1Z2WA 1OI8A 1U32A 3DW8C 4YKEA 4ORAA 4V0XA 3EGHA 2WDDA 3ZU0A 1S3LA 1XZWA 2XMOA 1JK7A 3K7WC 4IL1A 4MOVA 3RL5A 2NYMC 2USHA 2KKNA 2NPPC 3QFNA 4V0WA 3T1IA 2ZBMA 3JYFA 4DT2A 4FBKA 4ORBA 3DSCA 5C1VA 1NNWA 1TCOA 4KBPA 2A22A 4OR9A 4H1SA 3PSNA 1HP1A 2YVTA 2Z1AA 4I5LC 5INBA 1T71A 1USHA 2QFRA 1G5BA 1S3NA 3H69A 4O5GA 3IB7A 5F3WA 4ORCA 1MF8A 5J28A 2Z72A 4DHLA 2AHDA 3H64A 4H2BA 3E7AA 4XPNA 3H61A 1UF3A 3THNA 2WDFA 1SU1A 1XM7A 4V0VA 4H2IA 1QFCA 3QG5C 2BDXA 3C5WC 1M63A 4H1YP 4M0VA 3P71C 3QFKA 3V4YA 1V73A 1Z2XA 2JOGA 4JA7A 3RL3A 4F0ZA 1T70A 3N5UA 3ZTVA 1WAO1 3H68A 4LTYA 1HO5A 4WWLA 2BCDA 4ZX2A 1OIEA 2NXFA 3EGGA 3RQZA 5HPEA 2P6BA 4UT3B 5GTUA 2CV9A 3RL4A 4H2FA 3CK2A 4LACC 2NYLC 1QHWA 5JPEA 2WDEA 2IE3C 3TGHA 4FCXA 4O24A 4NZVA 1FJMA 1S95A 1S70A 3THOB 2GJUA 4UT2A 5IOHA 1UTEA
chains in the Genus database with same CATH superfamily
5DNYA 4KKZA 2HYOA 3AUZA 4ZVZA 3ICFA 4FBQA 3AV0A 1HPUA 4Q7FA 2DXLA 1WARA 3IVEA 3H63A 2O8GA 2BQ8X 3IB8A 3E7BA 3FGAC 4MP0A 4LU9A 3H60A 3D03A 2R17A 5EQVA 1AUIA 2Z06A 2QFPA 4HD0A 2O8AA 3HVQA 3QFOA 3IVDA 4DSYA 1IT6A 5B8IA 2HYPA 3KBPA 1OIDA 3C9FA 3H62B 3LL8A 4I5NC 4J6OA 4TUIA 4TUGA 3H66A 4G9JA 3DSDA 4FBWA 3GVEA 1S3MA 4B2OA 2IAEC 2WDCA 2HY1A 3K7VC 3H67A 1KBPA 4JA9A 2DFJA 5JPFA 3PSOA 1II7A 4H2GA 4MOYA 4O4KA 4IYPC 4UT3A 2Q8UA 4O43A 2IE4C 3QFMA 4UWQA 5JJTA 2QJCA 1S8EA 1W24A 1Z2WA 2ZOAA 1OI8A 2DXNA 1U32A 3DW8C 4YKEA 4ORAA 4V0XA 3EGHA 2WDDA 3ZU0A 1S3LA 1XZWA 2XMOA 1JK7A 3K7WC 4IL1A 4MOVA 3RL5A 2NYMC 2USHA 2KKNA 2NPPC 3QFNA 4V0WA 3T1IA 2ZBMA 3JYFA 4DT2A 4FBKA 2YEQA 4ORBA 3DSCA 5C1VA 1NNWA 1TCOA 4KBPA 2A22A 4OR9A 4H1SA 3PSNA 1HP1A 2YVTA 2Z1AA 4I5LC 5INBA 1T71A 1USHA 2QFRA 1G5BA 1S3NA 3H69A 4O5GA 3IB7A 5F3WA 4ORCA 1MF8A 5J28A 2Z72A 4DHLA 3E0JA 2AHDA 3H64A 4H2BA 3E7AA 4XPNA 3H61A 1UF3A 3FLOA 3THNA 2WDFA 1SU1A 1XM7A 4V0VA 4H2IA 1QFCA 3QG5C 2BDXA 3C5WC 1M63A 4H1YP 4M0VA 3P71C 3QFKA 3V4YA 1V73A 1Z2XA 2JOGA 4JA7A 3RL3A 4F0ZA 1T70A 3N5UA 3ZTVA 1WAO1 3H68A 4LTYA 1HO5A 2ZO9B 4WWLA 2BCDA 4ZX2A 1OIEA 2NXFA 3EGGA 3RQZA 5HPEA 2P6BA 4UT3B 5GTUA 2CV9A 3RL4A 4H2FA 3CK2A 4LACC 2NYLC 1QHWA 5JPEA 2WDEA 2IE3C 3TGHA 4FCXA 4O24A 4NZVA 1FJMA 1S95A 1S70A 3THOB 2GJUA 4UT2A 5IOHA 1UTEA
chains in the Genus database with same CATH topology
5DNYA 4KKZA 2HYOA 3AUZA 4ZVZA 3ICFA 4FBQA 3AV0A 1HPUA 4Q7FA 2DXLA 1WARA 3IVEA 3H63A 2O8GA 2BQ8X 3IB8A 3E7BA 3FGAC 4MP0A 4LU9A 3H60A 3D03A 2R17A 5EQVA 1AUIA 2Z06A 2QFPA 4HD0A 2O8AA 3HVQA 3QFOA 3IVDA 4DSYA 1IT6A 5B8IA 2HYPA 3KBPA 1OIDA 3C9FA 3H62B 3LL8A 4I5NC 4J6OA 4TUIA 4TUGA 3H66A 4G9JA 3DSDA 4FBWA 3GVEA 1S3MA 4B2OA 2IAEC 2WDCA 2HY1A 3K7VC 3H67A 1KBPA 4JA9A 2DFJA 5JPFA 3PSOA 1II7A 4H2GA 4MOYA 4O4KA 4IYPC 4UT3A 2Q8UA 4O43A 2IE4C 3QFMA 4UWQA 5JJTA 2QJCA 1S8EA 1W24A 1Z2WA 2ZOAA 1OI8A 2DXNA 1U32A 3DW8C 4YKEA 4ORAA 4V0XA 3EGHA 2WDDA 3ZU0A 1S3LA 1XZWA 2XMOA 1JK7A 3K7WC 4IL1A 4MOVA 3RL5A 2NYMC 2USHA 2KKNA 2NPPC 3QFNA 4V0WA 3T1IA 2ZBMA 3JYFA 4DT2A 4FBKA 2YEQA 4ORBA 3DSCA 5C1VA 1NNWA 1TCOA 4KBPA 2A22A 4OR9A 4H1SA 3PSNA 1HP1A 2YVTA 2Z1AA 4I5LC 5INBA 1T71A 1USHA 2QFRA 1G5BA 1S3NA 3H69A 4O5GA 3IB7A 5F3WA 4ORCA 1MF8A 5J28A 2Z72A 4DHLA 3E0JA 2AHDA 3H64A 4H2BA 3E7AA 4XPNA 3H61A 1UF3A 3FLOA 3THNA 2WDFA 1SU1A 1XM7A 4V0VA 4H2IA 1QFCA 3QG5C 2BDXA 3C5WC 1M63A 4H1YP 4M0VA 3P71C 3QFKA 3V4YA 1V73A 1Z2XA 2JOGA 4JA7A 3RL3A 4F0ZA 1T70A 3N5UA 3ZTVA 1WAO1 3H68A 4LTYA 1HO5A 2ZO9B 4WWLA 2BCDA 4ZX2A 1OIEA 2NXFA 3EGGA 3RQZA 5HPEA 2P6BA 4UT3B 5GTUA 2CV9A 3RL4A 4H2FA 3CK2A 4LACC 2NYLC 1QHWA 5JPEA 2WDEA 2IE3C 3TGHA 4FCXA 4O24A 4NZVA 1FJMA 1S95A 1S70A 3THOB 2GJUA 4UT2A 5IOHA 1UTEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DNY A;  4KKZ A;  2HYO A;  3AUZ A;  4ZVZ A;  3ICF A;  4FBQ A;  3AV0 A;  1HPU A;  4Q7F A;  1WAR A;  3IVE A;  3H63 A;  2O8G A;  2BQ8 X;  3IB8 A;  3E7B A;  3FGA C;  4MP0 A;  4LU9 A;  3H60 A;  2R17 A;  5EQV A;  1AUI A;  2Z06 A;  2QFP A;  4HD0 A;  2O8A A;  3HVQ A;  3QFO A;  3IVD A;  4DSY A;  1IT6 A;  5B8I A;  2HYP A;  3KBP A;  1OID A;  3C9F A;  3H62 B;  3LL8 A;  4I5N C;  4J6O A;  4TUI A;  4TUG A;  3H66 A;  4G9J A;  3DSD A;  4FBW A;  3GVE A;  1S3M A;  4B2O A;  2IAE C;  2WDC A;  2HY1 A;  3K7V C;  3H67 A;  1KBP A;  4JA9 A;  2DFJ A;  5JPF A;  3PSO A;  1II7 A;  4H2G A;  4MOY A;  4O4K A;  4IYP C;  4UT3 A;  2Q8U A;  4O43 A;  2IE4 C;  3QFM A;  4UWQ A;  5JJT A;  2QJC A;  1S8E A;  1W24 A;  1Z2W A;  1OI8 A;  1U32 A;  3DW8 C;  4YKE A;  4ORA A;  4V0X A;  3EGH A;  2WDD A;  3ZU0 A;  1S3L A;  1XZW A;  2XMO A;  1JK7 A;  3K7W C;  4IL1 A;  4MOV A;  3RL5 A;  2NYM C;  2USH A;  2KKN A;  2NPP C;  3QFN A;  4V0W A;  3T1I A;  2ZBM A;  3JYF A;  4DT2 A;  4FBK A;  4ORB A;  3DSC A;  5C1V A;  1NNW A;  1TCO A;  4KBP A;  2A22 A;  4OR9 A;  4H1S A;  3PSN A;  1HP1 A;  2YVT A;  2Z1A A;  4I5L C;  5INB A;  1T71 A;  1USH A;  2QFR A;  1G5B A;  1S3N A;  3H69 A;  4O5G A;  3IB7 A;  5F3W A;  4ORC A;  1MF8 A;  5J28 A;  2Z72 A;  4DHL A;  2AHD A;  3H64 A;  4H2B A;  3E7A A;  4XPN A;  3H61 A;  1UF3 A;  3THN A;  2WDF A;  1SU1 A;  1XM7 A;  4V0V A;  4H2I A;  1QFC A;  3QG5 C;  2BDX A;  3C5W C;  1M63 A;  4H1Y P;  4M0V A;  3P71 C;  3QFK A;  3V4Y A;  1V73 A;  1Z2X A;  2JOG A;  4JA7 A;  3RL3 A;  4F0Z A;  1T70 A;  3N5U A;  3ZTV A;  1WAO 1;  3H68 A;  4LTY A;  1HO5 A;  4WWL A;  2BCD A;  4ZX2 A;  1OIE A;  2NXF A;  3EGG A;  3RQZ A;  5HPE A;  2P6B A;  4UT3 B;  5GTU A;  2CV9 A;  3RL4 A;  4H2F A;  3CK2 A;  4LAC C;  2NYL C;  1QHW A;  5JPE A;  2WDE A;  2IE3 C;  3TGH A;  4FCX A;  4O24 A;  4NZV A;  1FJM A;  1S95 A;  1S70 A;  3THO B;  2GJU A;  4UT2 A;  5IOH A;  1UTE A; 
#chains in the Genus database with same CATH topology
 5DNY A;  4KKZ A;  2HYO A;  3AUZ A;  4ZVZ A;  3ICF A;  4FBQ A;  3AV0 A;  1HPU A;  4Q7F A;  2DXL A;  1WAR A;  3IVE A;  3H63 A;  2O8G A;  2BQ8 X;  3IB8 A;  3E7B A;  3FGA C;  4MP0 A;  4LU9 A;  3H60 A;  3D03 A;  2R17 A;  5EQV A;  1AUI A;  2Z06 A;  2QFP A;  4HD0 A;  2O8A A;  3HVQ A;  3QFO A;  3IVD A;  4DSY A;  1IT6 A;  5B8I A;  2HYP A;  3KBP A;  1OID A;  3C9F A;  3H62 B;  3LL8 A;  4I5N C;  4J6O A;  4TUI A;  4TUG A;  3H66 A;  4G9J A;  3DSD A;  4FBW A;  3GVE A;  1S3M A;  4B2O A;  2IAE C;  2WDC A;  2HY1 A;  3K7V C;  3H67 A;  1KBP A;  4JA9 A;  2DFJ A;  5JPF A;  3PSO A;  1II7 A;  4H2G A;  4MOY A;  4O4K A;  4IYP C;  4UT3 A;  2Q8U A;  4O43 A;  2IE4 C;  3QFM A;  4UWQ A;  5JJT A;  2QJC A;  1S8E A;  1W24 A;  1Z2W A;  2ZOA A;  1OI8 A;  2DXN A;  1U32 A;  3DW8 C;  4YKE A;  4ORA A;  4V0X A;  3EGH A;  2WDD A;  3ZU0 A;  1S3L A;  1XZW A;  2XMO A;  1JK7 A;  3K7W C;  4IL1 A;  4MOV A;  3RL5 A;  2NYM C;  2USH A;  2KKN A;  2NPP C;  3QFN A;  4V0W A;  3T1I A;  2ZBM A;  3JYF A;  4DT2 A;  4FBK A;  2YEQ A;  4ORB A;  3DSC A;  5C1V A;  1NNW A;  1TCO A;  4KBP A;  2A22 A;  4OR9 A;  4H1S A;  3PSN A;  1HP1 A;  2YVT A;  2Z1A A;  4I5L C;  5INB A;  1T71 A;  1USH A;  2QFR A;  1G5B A;  1S3N A;  3H69 A;  4O5G A;  3IB7 A;  5F3W A;  4ORC A;  1MF8 A;  5J28 A;  2Z72 A;  4DHL A;  3E0J A;  2AHD A;  3H64 A;  4H2B A;  3E7A A;  4XPN A;  3H61 A;  1UF3 A;  3FLO A;  3THN A;  2WDF A;  1SU1 A;  1XM7 A;  4V0V A;  4H2I A;  1QFC A;  3QG5 C;  2BDX A;  3C5W C;  1M63 A;  4H1Y P;  4M0V A;  3P71 C;  3QFK A;  3V4Y A;  1V73 A;  1Z2X A;  2JOG A;  4JA7 A;  3RL3 A;  4F0Z A;  1T70 A;  3N5U A;  3ZTV A;  1WAO 1;  3H68 A;  4LTY A;  1HO5 A;  2ZO9 B;  4WWL A;  2BCD A;  4ZX2 A;  1OIE A;  2NXF A;  3EGG A;  3RQZ A;  5HPE A;  2P6B A;  4UT3 B;  5GTU A;  2CV9 A;  3RL4 A;  4H2F A;  3CK2 A;  4LAC C;  2NYL C;  1QHW A;  5JPE A;  2WDE A;  2IE3 C;  3TGH A;  4FCX A;  4O24 A;  4NZV A;  1FJM A;  1S95 A;  1S70 A;  3THO B;  2GJU A;  4UT2 A;  5IOH A;  1UTE A; 
#chains in the Genus database with same CATH homology
 5DNY A;  4KKZ A;  2HYO A;  3AUZ A;  4ZVZ A;  3ICF A;  4FBQ A;  3AV0 A;  1HPU A;  4Q7F A;  2DXL A;  1WAR A;  3IVE A;  3H63 A;  2O8G A;  2BQ8 X;  3IB8 A;  3E7B A;  3FGA C;  4MP0 A;  4LU9 A;  3H60 A;  3D03 A;  2R17 A;  5EQV A;  1AUI A;  2Z06 A;  2QFP A;  4HD0 A;  2O8A A;  3HVQ A;  3QFO A;  3IVD A;  4DSY A;  1IT6 A;  5B8I A;  2HYP A;  3KBP A;  1OID A;  3C9F A;  3H62 B;  3LL8 A;  4I5N C;  4J6O A;  4TUI A;  4TUG A;  3H66 A;  4G9J A;  3DSD A;  4FBW A;  3GVE A;  1S3M A;  4B2O A;  2IAE C;  2WDC A;  2HY1 A;  3K7V C;  3H67 A;  1KBP A;  4JA9 A;  2DFJ A;  5JPF A;  3PSO A;  1II7 A;  4H2G A;  4MOY A;  4O4K A;  4IYP C;  4UT3 A;  2Q8U A;  4O43 A;  2IE4 C;  3QFM A;  4UWQ A;  5JJT A;  2QJC A;  1S8E A;  1W24 A;  1Z2W A;  2ZOA A;  1OI8 A;  2DXN A;  1U32 A;  3DW8 C;  4YKE A;  4ORA A;  4V0X A;  3EGH A;  2WDD A;  3ZU0 A;  1S3L A;  1XZW A;  2XMO A;  1JK7 A;  3K7W C;  4IL1 A;  4MOV A;  3RL5 A;  2NYM C;  2USH A;  2KKN A;  2NPP C;  3QFN A;  4V0W A;  3T1I A;  2ZBM A;  3JYF A;  4DT2 A;  4FBK A;  2YEQ A;  4ORB A;  3DSC A;  5C1V A;  1NNW A;  1TCO A;  4KBP A;  2A22 A;  4OR9 A;  4H1S A;  3PSN A;  1HP1 A;  2YVT A;  2Z1A A;  4I5L C;  5INB A;  1T71 A;  1USH A;  2QFR A;  1G5B A;  1S3N A;  3H69 A;  4O5G A;  3IB7 A;  5F3W A;  4ORC A;  1MF8 A;  5J28 A;  2Z72 A;  4DHL A;  3E0J A;  2AHD A;  3H64 A;  4H2B A;  3E7A A;  4XPN A;  3H61 A;  1UF3 A;  3FLO A;  3THN A;  2WDF A;  1SU1 A;  1XM7 A;  4V0V A;  4H2I A;  1QFC A;  3QG5 C;  2BDX A;  3C5W C;  1M63 A;  4H1Y P;  4M0V A;  3P71 C;  3QFK A;  3V4Y A;  1V73 A;  1Z2X A;  2JOG A;  4JA7 A;  3RL3 A;  4F0Z A;  1T70 A;  3N5U A;  3ZTV A;  1WAO 1;  3H68 A;  4LTY A;  1HO5 A;  2ZO9 B;  4WWL A;  2BCD A;  4ZX2 A;  1OIE A;  2NXF A;  3EGG A;  3RQZ A;  5HPE A;  2P6B A;  4UT3 B;  5GTU A;  2CV9 A;  3RL4 A;  4H2F A;  3CK2 A;  4LAC C;  2NYL C;  1QHW A;  5JPE A;  2WDE A;  2IE3 C;  3TGH A;  4FCX A;  4O24 A;  4NZV A;  1FJM A;  1S95 A;  1S70 A;  3THO B;  2GJU A;  4UT2 A;  5IOH A;  1UTE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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