1OIEA

5'-nucleotidase (e. coli) with an engineered disulfide bridge (s228c, p513c)
Total Genus 171
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
171
sequence length
525
structure length
519
Chain Sequence
YEQDKTYKITVLHTNDHHGHFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLLSGGDINTGVPESDLQDAEPDFRGMNLVGYDAMAIGNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWALFKRQDLKIAVIGLTTDDTAKIGNPEYFTDIEFRKPADEAKLVIQELQQTEKPDIIIAATHMGHYDNGEHGCNAPGDVEMARALPAGSLAMIVGGHSQDPVCMAAENKKQVDYVPGTPCKPDQQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVSERVLYTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQTNMGRLILAAQMDRTGADFAVMSGGGIRDSIEAGDISYKNVLKVQPFGNVVVYADMTGKEVIDYLTAVAQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPAKTYRMATLNFNATGGDGYPRLDNKCGYVNTGFIDAEVLKAYIQKSSPLDVSVYEPKGEVSWQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Trapping a 96 Degree Domain Rotation in Two Distinct Conformations by Engineered Disulfide Bridges
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords PROTEIN USHA
total genus 171
structure length 519
sequence length 525
ec nomenclature ec 3.1.3.5: 5'-nucleotidase.
pdb deposition date 2003-06-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF02872 5_nucleotid_C 5'-nucleotidase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 1oieA01
3.90.780.10 Alpha Beta Alpha-Beta Complex 5'-nucleotidase; domain 2 5'-Nucleotidase, C-terminal domain 1oieA02
2USHA 1Z2XA 2IAEC 2Z06A 4NZVA 3QG5C 5JPFA 4O43A 1JK7A 1USHA 1OIEA 2GJUA 2ZBMA 1IT6A 1T70A 4MP0A 3ZU0A 5EQVA 3ZTVA 5HPEA 4DHLA 2NPPC 2WDEA 3QFNA 2YVTA 1UF3A 3DSCA 5IOHA 4G9JA 3IVEA 1WARA 4FBKA 4UWQA 5INBA 3N5UA 1FJMA 4UT2A 4LACC 4OR9A 1S3MA 1S70A 3AV0A 1V73A 2BCDA 2R17A 1UTEA 2IE3C 1XZWA 4H2GA 2NYMC 4I5LC 3K7WC 4IYPC 3H64A 4KBPA 3RL5A 1G5BA 3H62B 3THNA 2DFJA 2NXFA 3IVDA 1HP1A 3E7BA 1Z2WA 4WWLA 3H67A 1SU1A 1T71A 3AUZA 3THOB 3H66A 4H2IA 1MF8A 4I5NC 2WDFA 4H1SA 3C5WC 3H63A 2Z72A 4JA7A 5F3WA 1OIDA 3QFKA 4O5GA 4MOVA 3V4YA 1NNWA 5B8IA 1OI8A 3KBPA 1S95A 4ORBA 3PSNA 2JOGA 2QJCA 4HD0A 3H61A 4FBWA 3GVEA 4TUGA 2A22A 1II7A 2NYLC 3E7AA 4O24A 2QFPA 4V0WA 4ZX2A 1W24A 3RL4A 4DT2A 2QFRA 2BQ8X 4H2FA 1TCOA 3DSDA 3K7VC 4TUIA 2O8AA 4V0XA 2HY1A 2CV9A 1WAO1 4DSYA 4KKZA 4MOYA 4V0VA 3FGAC 3TGHA 2AHDA 4Q7FA 3T1IA 1KBPA 4F0ZA 5JJTA 3JYFA 3HVQA 3H69A 4H2BA 2WDDA 4ZVZA 3C9FA 3IB7A 4JA9A 4UT3A 3EGHA 2O8GA 1HPUA 5J28A 3ICFA 2IE4C 2Z1AA 3CK2A 4LU9A 2WDCA 2HYOA 4YKEA 3RQZA 3EGGA 1S3LA 1S3NA 3LL8A 4ORAA 1XM7A 5C1VA 4LTYA 2Q8UA 3DW8C 4H1YP 2XMOA 1U32A 5DNYA 4UT3B 2HYPA 4FBQA 4FCXA 1M63A 4J6OA 2BDXA 1QHWA 1QFCA 5JPEA 4ORCA 2P6BA 3QFOA 3RL3A 4IL1A 3PSOA 5GTUA 3P71C 4O4KA 2KKNA 4XPNA 3H68A 3QFMA 1HO5A 3IB8A 1AUIA 3H60A 4M0VA 4B2OA 1S8EA
chains in the Genus database with same CATH superfamily
2USHA 1Z2XA 2IAEC 2Z06A 4NZVA 3E0JA 3QG5C 4O43A 5JPFA 1JK7A 1USHA 1OIEA 2GJUA 2ZBMA 1IT6A 1T70A 4MP0A 3ZU0A 5EQVA 3ZTVA 5HPEA 4DHLA 2NPPC 2WDEA 3QFNA 2YVTA 1UF3A 3DSCA 5IOHA 4G9JA 3IVEA 1WARA 4FBKA 4UWQA 5INBA 3N5UA 1FJMA 4UT2A 4LACC 4OR9A 1S3MA 1S70A 3AV0A 1V73A 2BCDA 2R17A 1UTEA 2IE3C 1XZWA 4H2GA 2NYMC 4I5LC 3K7WC 4IYPC 3H64A 4KBPA 3RL5A 1G5BA 3H62B 3THNA 2DFJA 2NXFA 3IVDA 1HP1A 3E7BA 1Z2WA 4WWLA 3H67A 1SU1A 1T71A 3AUZA 3THOB 3H66A 4H2IA 1MF8A 4I5NC 2WDFA 4H1SA 3C5WC 3H63A 2Z72A 4JA7A 5F3WA 1OIDA 3QFKA 4O5GA 2DXLA 4MOVA 3V4YA 1NNWA 5B8IA 1OI8A 3KBPA 1S95A 4ORBA 3PSNA 2JOGA 2QJCA 4HD0A 3H61A 4FBWA 3GVEA 4TUGA 2A22A 1II7A 2NYLC 3E7AA 4O24A 2QFPA 4V0WA 4ZX2A 1W24A 3RL4A 4DT2A 2QFRA 2BQ8X 4H2FA 2ZOAA 1TCOA 3DSDA 3K7VC 4TUIA 2O8AA 4V0XA 2HY1A 2CV9A 1WAO1 4DSYA 4KKZA 4MOYA 4V0VA 3FGAC 3TGHA 2AHDA 4Q7FA 3T1IA 1KBPA 4F0ZA 5JJTA 3JYFA 3HVQA 3H69A 4H2BA 2WDDA 4ZVZA 3C9FA 3IB7A 4JA9A 4UT3A 2ZO9B 3EGHA 2O8GA 3D03A 1HPUA 5J28A 3ICFA 2IE4C 2Z1AA 3CK2A 4LU9A 2WDCA 2HYOA 4YKEA 3RQZA 3EGGA 1S3LA 1S3NA 3LL8A 4ORAA 1XM7A 5C1VA 4LTYA 2Q8UA 3DW8C 4H1YP 2XMOA 1U32A 3FLOA 5DNYA 4UT3B 2YEQA 2HYPA 4FBQA 4FCXA 1M63A 4J6OA 2BDXA 1QHWA 1QFCA 5JPEA 4ORCA 2P6BA 3QFOA 3RL3A 4IL1A 2DXNA 3PSOA 5GTUA 3P71C 4O4KA 2KKNA 4XPNA 3H68A 3QFMA 1HO5A 3IB8A 1AUIA 3H60A 4M0VA 4B2OA 1S8EA
chains in the Genus database with same CATH topology
2USHA 1Z2XA 2IAEC 2Z06A 4NZVA 3E0JA 3QG5C 4O43A 5JPFA 1JK7A 1USHA 1OIEA 2GJUA 2ZBMA 1IT6A 1T70A 4MP0A 3ZU0A 5EQVA 3ZTVA 5HPEA 4DHLA 2NPPC 2WDEA 3QFNA 2YVTA 1UF3A 3DSCA 5IOHA 4G9JA 3IVEA 1WARA 4FBKA 4UWQA 5INBA 3N5UA 1FJMA 4UT2A 4LACC 4OR9A 1S3MA 1S70A 3AV0A 1V73A 2BCDA 2R17A 1UTEA 2IE3C 1XZWA 4H2GA 2NYMC 4I5LC 3K7WC 4IYPC 3H64A 4KBPA 3RL5A 1G5BA 3H62B 3THNA 2DFJA 2NXFA 3IVDA 1HP1A 3E7BA 1Z2WA 4WWLA 3H67A 1SU1A 1T71A 3AUZA 3THOB 3H66A 4H2IA 1MF8A 4I5NC 2WDFA 4H1SA 3C5WC 3H63A 2Z72A 4JA7A 5F3WA 1OIDA 3QFKA 4O5GA 2DXLA 4MOVA 3V4YA 1NNWA 5B8IA 1OI8A 3KBPA 1S95A 4ORBA 3PSNA 2JOGA 2QJCA 4HD0A 3H61A 4FBWA 3GVEA 4TUGA 2A22A 1II7A 2NYLC 3E7AA 4O24A 2QFPA 4V0WA 4ZX2A 1W24A 3RL4A 4DT2A 2QFRA 2BQ8X 4H2FA 2ZOAA 1TCOA 3DSDA 3K7VC 4TUIA 2O8AA 4V0XA 2HY1A 2CV9A 1WAO1 4DSYA 4KKZA 4MOYA 4V0VA 3FGAC 3TGHA 2AHDA 4Q7FA 3T1IA 1KBPA 4F0ZA 5JJTA 3JYFA 3HVQA 3H69A 4H2BA 2WDDA 4ZVZA 3C9FA 3IB7A 4JA9A 4UT3A 2ZO9B 3EGHA 2O8GA 3D03A 1HPUA 5J28A 3ICFA 2IE4C 2Z1AA 3CK2A 4LU9A 2WDCA 2HYOA 4YKEA 3RQZA 3EGGA 1S3LA 1S3NA 3LL8A 4ORAA 1XM7A 5C1VA 4LTYA 2Q8UA 3DW8C 4H1YP 2XMOA 1U32A 3FLOA 5DNYA 4UT3B 2YEQA 2HYPA 4FBQA 4FCXA 1M63A 4J6OA 2BDXA 1QHWA 1QFCA 5JPEA 4ORCA 2P6BA 3QFOA 3RL3A 4IL1A 2DXNA 3PSOA 5GTUA 3P71C 4O4KA 2KKNA 4XPNA 3H68A 3QFMA 1HO5A 3IB8A 1AUIA 3H60A 4M0VA 4B2OA 1S8EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2USH A;  1Z2X A;  2IAE C;  2Z06 A;  4NZV A;  3QG5 C;  5JPF A;  4O43 A;  1JK7 A;  1USH A;  1OIE A;  2GJU A;  2ZBM A;  1IT6 A;  1T70 A;  4MP0 A;  3ZU0 A;  5EQV A;  3ZTV A;  5HPE A;  4DHL A;  2NPP C;  2WDE A;  3QFN A;  2YVT A;  1UF3 A;  3DSC A;  5IOH A;  4G9J A;  3IVE A;  1WAR A;  4FBK A;  4UWQ A;  5INB A;  3N5U A;  1FJM A;  4UT2 A;  4LAC C;  4OR9 A;  1S3M A;  1S70 A;  3AV0 A;  1V73 A;  2BCD A;  2R17 A;  1UTE A;  2IE3 C;  1XZW A;  4H2G A;  2NYM C;  4I5L C;  3K7W C;  4IYP C;  3H64 A;  4KBP A;  3RL5 A;  1G5B A;  3H62 B;  3THN A;  2DFJ A;  2NXF A;  3IVD A;  1HP1 A;  3E7B A;  1Z2W A;  4WWL A;  3H67 A;  1SU1 A;  1T71 A;  3AUZ A;  3THO B;  3H66 A;  4H2I A;  1MF8 A;  4I5N C;  2WDF A;  4H1S A;  3C5W C;  3H63 A;  2Z72 A;  4JA7 A;  5F3W A;  1OID A;  3QFK A;  4O5G A;  4MOV A;  3V4Y A;  1NNW A;  5B8I A;  1OI8 A;  3KBP A;  1S95 A;  4ORB A;  3PSN A;  2JOG A;  2QJC A;  4HD0 A;  3H61 A;  4FBW A;  3GVE A;  4TUG A;  2A22 A;  1II7 A;  2NYL C;  3E7A A;  4O24 A;  2QFP A;  4V0W A;  4ZX2 A;  1W24 A;  3RL4 A;  4DT2 A;  2QFR A;  2BQ8 X;  4H2F A;  1TCO A;  3DSD A;  3K7V C;  4TUI A;  2O8A A;  4V0X A;  2HY1 A;  2CV9 A;  1WAO 1;  4DSY A;  4KKZ A;  4MOY A;  4V0V A;  3FGA C;  3TGH A;  2AHD A;  4Q7F A;  3T1I A;  1KBP A;  4F0Z A;  5JJT A;  3JYF A;  3HVQ A;  3H69 A;  4H2B A;  2WDD A;  4ZVZ A;  3C9F A;  3IB7 A;  4JA9 A;  4UT3 A;  3EGH A;  2O8G A;  1HPU A;  5J28 A;  3ICF A;  2IE4 C;  2Z1A A;  3CK2 A;  4LU9 A;  2WDC A;  2HYO A;  4YKE A;  3RQZ A;  3EGG A;  1S3L A;  1S3N A;  3LL8 A;  4ORA A;  1XM7 A;  5C1V A;  4LTY A;  2Q8U A;  3DW8 C;  4H1Y P;  2XMO A;  1U32 A;  5DNY A;  4UT3 B;  2HYP A;  4FBQ A;  4FCX A;  1M63 A;  4J6O A;  2BDX A;  1QHW A;  1QFC A;  5JPE A;  4ORC A;  2P6B A;  3QFO A;  3RL3 A;  4IL1 A;  3PSO A;  5GTU A;  3P71 C;  4O4K A;  2KKN A;  4XPN A;  3H68 A;  3QFM A;  1HO5 A;  3IB8 A;  1AUI A;  3H60 A;  4M0V A;  4B2O A;  1S8E A; 
#chains in the Genus database with same CATH topology
 2USH A;  1Z2X A;  2IAE C;  2Z06 A;  4NZV A;  3E0J A;  3QG5 C;  4O43 A;  5JPF A;  1JK7 A;  1USH A;  1OIE A;  2GJU A;  2ZBM A;  1IT6 A;  1T70 A;  4MP0 A;  3ZU0 A;  5EQV A;  3ZTV A;  5HPE A;  4DHL A;  2NPP C;  2WDE A;  3QFN A;  2YVT A;  1UF3 A;  3DSC A;  5IOH A;  4G9J A;  3IVE A;  1WAR A;  4FBK A;  4UWQ A;  5INB A;  3N5U A;  1FJM A;  4UT2 A;  4LAC C;  4OR9 A;  1S3M A;  1S70 A;  3AV0 A;  1V73 A;  2BCD A;  2R17 A;  1UTE A;  2IE3 C;  1XZW A;  4H2G A;  2NYM C;  4I5L C;  3K7W C;  4IYP C;  3H64 A;  4KBP A;  3RL5 A;  1G5B A;  3H62 B;  3THN A;  2DFJ A;  2NXF A;  3IVD A;  1HP1 A;  3E7B A;  1Z2W A;  4WWL A;  3H67 A;  1SU1 A;  1T71 A;  3AUZ A;  3THO B;  3H66 A;  4H2I A;  1MF8 A;  4I5N C;  2WDF A;  4H1S A;  3C5W C;  3H63 A;  2Z72 A;  4JA7 A;  5F3W A;  1OID A;  3QFK A;  4O5G A;  2DXL A;  4MOV A;  3V4Y A;  1NNW A;  5B8I A;  1OI8 A;  3KBP A;  1S95 A;  4ORB A;  3PSN A;  2JOG A;  2QJC A;  4HD0 A;  3H61 A;  4FBW A;  3GVE A;  4TUG A;  2A22 A;  1II7 A;  2NYL C;  3E7A A;  4O24 A;  2QFP A;  4V0W A;  4ZX2 A;  1W24 A;  3RL4 A;  4DT2 A;  2QFR A;  2BQ8 X;  4H2F A;  2ZOA A;  1TCO A;  3DSD A;  3K7V C;  4TUI A;  2O8A A;  4V0X A;  2HY1 A;  2CV9 A;  1WAO 1;  4DSY A;  4KKZ A;  4MOY A;  4V0V A;  3FGA C;  3TGH A;  2AHD A;  4Q7F A;  3T1I A;  1KBP A;  4F0Z A;  5JJT A;  3JYF A;  3HVQ A;  3H69 A;  4H2B A;  2WDD A;  4ZVZ A;  3C9F A;  3IB7 A;  4JA9 A;  4UT3 A;  2ZO9 B;  3EGH A;  2O8G A;  3D03 A;  1HPU A;  5J28 A;  3ICF A;  2IE4 C;  2Z1A A;  3CK2 A;  4LU9 A;  2WDC A;  2HYO A;  4YKE A;  3RQZ A;  3EGG A;  1S3L A;  1S3N A;  3LL8 A;  4ORA A;  1XM7 A;  5C1V A;  4LTY A;  2Q8U A;  3DW8 C;  4H1Y P;  2XMO A;  1U32 A;  3FLO A;  5DNY A;  4UT3 B;  2YEQ A;  2HYP A;  4FBQ A;  4FCX A;  1M63 A;  4J6O A;  2BDX A;  1QHW A;  1QFC A;  5JPE A;  4ORC A;  2P6B A;  3QFO A;  3RL3 A;  4IL1 A;  2DXN A;  3PSO A;  5GTU A;  3P71 C;  4O4K A;  2KKN A;  4XPN A;  3H68 A;  3QFM A;  1HO5 A;  3IB8 A;  1AUI A;  3H60 A;  4M0V A;  4B2O A;  1S8E A; 
#chains in the Genus database with same CATH homology
 2USH A;  1Z2X A;  2IAE C;  2Z06 A;  4NZV A;  3E0J A;  3QG5 C;  4O43 A;  5JPF A;  1JK7 A;  1USH A;  1OIE A;  2GJU A;  2ZBM A;  1IT6 A;  1T70 A;  4MP0 A;  3ZU0 A;  5EQV A;  3ZTV A;  5HPE A;  4DHL A;  2NPP C;  2WDE A;  3QFN A;  2YVT A;  1UF3 A;  3DSC A;  5IOH A;  4G9J A;  3IVE A;  1WAR A;  4FBK A;  4UWQ A;  5INB A;  3N5U A;  1FJM A;  4UT2 A;  4LAC C;  4OR9 A;  1S3M A;  1S70 A;  3AV0 A;  1V73 A;  2BCD A;  2R17 A;  1UTE A;  2IE3 C;  1XZW A;  4H2G A;  2NYM C;  4I5L C;  3K7W C;  4IYP C;  3H64 A;  4KBP A;  3RL5 A;  1G5B A;  3H62 B;  3THN A;  2DFJ A;  2NXF A;  3IVD A;  1HP1 A;  3E7B A;  1Z2W A;  4WWL A;  3H67 A;  1SU1 A;  1T71 A;  3AUZ A;  3THO B;  3H66 A;  4H2I A;  1MF8 A;  4I5N C;  2WDF A;  4H1S A;  3C5W C;  3H63 A;  2Z72 A;  4JA7 A;  5F3W A;  1OID A;  3QFK A;  4O5G A;  2DXL A;  4MOV A;  3V4Y A;  1NNW A;  5B8I A;  1OI8 A;  3KBP A;  1S95 A;  4ORB A;  3PSN A;  2JOG A;  2QJC A;  4HD0 A;  3H61 A;  4FBW A;  3GVE A;  4TUG A;  2A22 A;  1II7 A;  2NYL C;  3E7A A;  4O24 A;  2QFP A;  4V0W A;  4ZX2 A;  1W24 A;  3RL4 A;  4DT2 A;  2QFR A;  2BQ8 X;  4H2F A;  2ZOA A;  1TCO A;  3DSD A;  3K7V C;  4TUI A;  2O8A A;  4V0X A;  2HY1 A;  2CV9 A;  1WAO 1;  4DSY A;  4KKZ A;  4MOY A;  4V0V A;  3FGA C;  3TGH A;  2AHD A;  4Q7F A;  3T1I A;  1KBP A;  4F0Z A;  5JJT A;  3JYF A;  3HVQ A;  3H69 A;  4H2B A;  2WDD A;  4ZVZ A;  3C9F A;  3IB7 A;  4JA9 A;  4UT3 A;  2ZO9 B;  3EGH A;  2O8G A;  3D03 A;  1HPU A;  5J28 A;  3ICF A;  2IE4 C;  2Z1A A;  3CK2 A;  4LU9 A;  2WDC A;  2HYO A;  4YKE A;  3RQZ A;  3EGG A;  1S3L A;  1S3N A;  3LL8 A;  4ORA A;  1XM7 A;  5C1V A;  4LTY A;  2Q8U A;  3DW8 C;  4H1Y P;  2XMO A;  1U32 A;  3FLO A;  5DNY A;  4UT3 B;  2YEQ A;  2HYP A;  4FBQ A;  4FCX A;  1M63 A;  4J6O A;  2BDX A;  1QHW A;  1QFC A;  5JPE A;  4ORC A;  2P6B A;  3QFO A;  3RL3 A;  4IL1 A;  2DXN A;  3PSO A;  5GTU A;  3P71 C;  4O4K A;  2KKN A;  4XPN A;  3H68 A;  3QFM A;  1HO5 A;  3IB8 A;  1AUI A;  3H60 A;  4M0V A;  4B2O A;  1S8E A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...