1R9TL

Rna polymerase ii strand separated elongation complex, mismatched nucleotide
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
pubmed doi rcsb
molecule tags Transcription/dna-rna hybrid
molecule keywords RNA strand
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2003-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 1r9tL00
2E2IL 5M3FL 3GTLL 4BXXL 4Y52L 3H3VM 1TWHL 4AYBP 2B63L 2E2HL 2E2JL 2NVXL 3S1RL 3S17L 4A3LL 1WCML 5IP9L 3S1NL 5IYCL 3RZDL 5M5WL 2WAQP 1R9TL 3GTGL 5C44L 5C3EL 2NVYL 2WB1P 2JA5L 2R92L 3CQZL 1I50L 5IP7L 3GTML 5C4XL 1TWAL 3HKZP 3S14L 3HOVL 3PO3L 3PO2L 2JA8L 1Y1VL 2VUML 2JA7L 2NVQL 3S2DL 4Y7NL 3GTPL 1Y1WL 3HOXL 4BBRL 4BY1L 3HOUL 3GTOL 3M3YL 5M5XL 4A3KL 4A3EL 1TWGL 4A3FL 5M3ML 1TWFL 4A3ML 1I3QL 3FKIL 2NVTL 3I4ML 4QIWP 1K83L 3GTJL 3H0GL 4A93L 4A3DL 4A3JL 3HOWL 1TWCL 4X6AL 5IYDL 3S2HL 4A3BL 3RZOL 4A3CL 2R7ZL 2Y0SP 4C3HL 2R93L 4C3IL 5IYBL 3S1ML 5FJ8L 3GTKL 4BY7L 3HOYL 3K7AL 5FLML 4A3GL 4C3JL 3S1QL 3HOZL 5M5YL 2YU9L 3I4NL 4A3IL 3M4OL 3GTQL 1SFOL 2JA6L 3S16L 1I6HL 4C2M1 3S15L 5C4JL 4BBSL 2PMZP
chains in the Genus database with same CATH superfamily
3GTLL 2XJQA 4AYBP 3ZG6A 5GADc 2E2HL 2QL0A 2E2JL 4AHWA 1LKMA 3PZAA 2AUSB 3NFPI 5IP9L 3RZ6A 1RB9A 3KYXA 3RZDL 1B13A 4WFN1 3H9BA 3H99A 4RXNA 2C6BA 3LPEB 1DVBA 1SMMA 3LWVB 3LWQB 4AI0A 2DSXA 4LHNA 3HKZP 3HOVL 3P8BA 1P7PA 4LHLA 5H1Sc 4YWLA 1C09A 1QCVA 1VZIA 2VUML 3S2DL 3GTPL 4BBRL 4BY1L 3HOUL 3GTOL 4YWMA 1F4LA 1R0FA 4A3FL 4ZN1B 2EY4E 2A6ED 1S2ZA 1OWCA 4QIWP 1JYBA 4TPUA 4A3JL 3HOWL 1TWCL 5IYDL 5RXNA 5EINC 4A3BL 3RZOL 5EIOC 2R7ZL 1RYTA 2Y0SP 4C3HL 5IYBL 3QQCE 3GTKL 1OWBA 1ZRPA 3HOYL 1R0IA 2PVXA 1CADA 2PPTA 2XJPA 4XGHA 2XJRA 5MLC3 3I4NL 1CAAA 3J7Y1 3MSUA 2LCQA 3SS2A 1I6HL 4AHXA 3FDJA 4XXBB 3JR7A 4ME3A 3H3VM 1TWHL 3H9CA 2B63L 3HAXC 4JAGA 1PFYA 3S17L 1WCML 2Z3QB 3S1NL 3WWLA 4TVMA 2WAQP 2XJTA 1R9TL 3GTGL 1SMWA 5C44L 4K9FA 5IY0A 2XJUA 2PYAA 2WB1P 2NYDA 2JA5L 1S24A 2MS3A 2ERJA 5C4XL 2B5ID 2CKCA 1TWAL 2H12A 3PO2L 4AR6A 2JA8L 1IU5A 1RDVA 1YUXA 5K2ME 3HOXL 2GMGA 3LWRB 1PFVA 5M3ML 1LKOA 3RZTA 5AI3A 5DM71 3VPBE 1I3QL 2JI1A 3FKIL 2NVTL 2K2DA 1K83L 3GTJL 1LKPA 5JVH1 4A93L 2V0EA 2JI2A 1YUZA 2C6AA 1Z92B 4BY7L 4A3GL 3MQKB 3HOZL 5GAEc 4A3IL 1E8JA 3GTQL 1R0HA 3H97A 3IU3I 4POFA 4C2M1 5C4JL 5GAGc 4BBSL 1B71A 5M3FL 1VZHA 3PWFA 4AR5A 2RDVA 3HJWB 2Z3RB 3QVDA 1R0JA 5IYCL 7RXNA 1PZXA 3KYYA 2RFKB 4AR3A 1RYQA 3CQZL 1NNQA 3LWPB 1I50L 1SMUA 5IP7L 3A44A 3B0AB 3GTML 3KYUA 3J7Z1 4B8CD 3LWOB 2AQCA 1S30A 1WJVA 1T9PA 2A68D 1YK5A 4A3KL 2CKAA 1BRFA 1PFUA 3PKIA 1T9QA 1NXEA 3PKJA 1VZGA 1BFYA 4AI2A 3I4ML 3H0GL 4POGA 1BQ9A 1LTLA 2XJSA 4X6AL 3PL5A 2A69D 3S2HL 4V196 3HJYB 4A3CL 2M4VA 4AHYA 2ERSA 2R93L 2JI3A 1IRNA 2L0ZA 4AI1A 3S1ML 2BE5D 5FLML 4G6BA 2PSMC 5MF6A 5DM61 1IW7D 2ZIXA 5MFZA 3M4OL 1IU6A 2J9UB 5GAHc 2KN9A 3PIO1 1SFOL 3S16L 3S15L 2M4YA 1VCXA 2E2IL 8RXNA 2VL6A 4BXXL 2HVYC 4Y52L 1DX8A 2V3BB 2NVXL 3MPSA 3S1RL 3KYVA 4U671 4A3LL 1BQ8A 4AR4A 4GS7D 5M5WL 1H7VA 3KYWA 5AN9H 1ODHA 5C3EL 5AI2A 4JADA 2NVYL 4JAEA 1YK4A 2R92L 2XJVA 3S14L 3PO3L 1Y1VL 3B08B 2JA7L 2NVQL 5JVG1 4Y7NL 1Y1WL 1YV1A 2AYJA 3M3YL 4AI3A 5M5XL 4A3EL 1TWGL 1RDGA 1FHHA 3RYGA 1TWFL 4A3ML 6RXNA 1RWDA 2KKDA 1R0GA 4E6YA 2HR5A 1QYBA 4A3DL 1FHMA 5MGNA 1IROA 2M6PA 2M6OA 3WWNB 4C3IL 4JAFA 4AHZA 1PFWA 5FJ8L 1T9OA 3K7AL 3PIP1 4C3JL 3S1QL 1NXGA 2PVEA 4UY81 2APOB 5M5YL 2YU9L 1B2OA 3LNLA 2O5JD 2A6HD 3K35A 2V0FA 1B2JA 1BE7A 4ZN3B 1QQTA 2JA6L 2CR8A 3P2AA 5MFPA 2PMZP
chains in the Genus database with same CATH topology
2E2IL 5M3FL 3GTLL 4BXXL 4Y52L 3H3VM 1TWHL 4AYBP 2B63L 2E2HL 2E2JL 2NVXL 3S1RL 3S17L 4A3LL 1WCML 5IP9L 3S1NL 5IYCL 3RZDL 5M5WL 2WAQP 1R9TL 3GTGL 5C44L 5C3EL 2NVYL 2WB1P 2JA5L 2R92L 3CQZL 1I50L 5IP7L 3GTML 5C4XL 1TWAL 3HKZP 3S14L 3HOVL 3PO3L 3PO2L 2JA8L 1Y1VL 2VUML 2JA7L 2NVQL 3S2DL 4Y7NL 3GTPL 1Y1WL 3HOXL 4BBRL 4BY1L 3HOUL 3GTOL 3M3YL 5M5XL 4A3KL 4A3EL 1TWGL 4A3FL 5M3ML 1TWFL 4A3ML 1I3QL 3FKIL 2NVTL 3I4ML 4QIWP 1K83L 3GTJL 3H0GL 4A93L 4A3DL 4A3JL 3HOWL 1TWCL 4X6AL 5IYDL 3S2HL 4A3BL 3RZOL 4A3CL 2R7ZL 2Y0SP 4C3HL 2R93L 4C3IL 5IYBL 3S1ML 5FJ8L 3GTKL 4BY7L 3HOYL 3K7AL 5FLML 4A3GL 4C3JL 3S1QL 3HOZL 5M5YL 2YU9L 3I4NL 4A3IL 3M4OL 3GTQL 1SFOL 2JA6L 3S16L 1I6HL 4C2M1 3S15L 5C4JL 4BBSL 2PMZP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E2I L;  5M3F L;  3GTL L;  4BXX L;  4Y52 L;  3H3V M;  1TWH L;  4AYB P;  2B63 L;  2E2H L;  2E2J L;  2NVX L;  3S1R L;  3S17 L;  4A3L L;  1WCM L;  5IP9 L;  3S1N L;  5IYC L;  3RZD L;  5M5W L;  2WAQ P;  1R9T L;  3GTG L;  5C44 L;  5C3E L;  2NVY L;  2WB1 P;  2JA5 L;  2R92 L;  3CQZ L;  1I50 L;  5IP7 L;  3GTM L;  5C4X L;  1TWA L;  3HKZ P;  3S14 L;  3HOV L;  3PO3 L;  3PO2 L;  2JA8 L;  1Y1V L;  2VUM L;  2JA7 L;  2NVQ L;  3S2D L;  4Y7N L;  3GTP L;  1Y1W L;  3HOX L;  4BBR L;  4BY1 L;  3HOU L;  3GTO L;  3M3Y L;  5M5X L;  4A3K L;  4A3E L;  1TWG L;  4A3F L;  5M3M L;  1TWF L;  4A3M L;  1I3Q L;  3FKI L;  2NVT L;  3I4M L;  4QIW P;  1K83 L;  3GTJ L;  3H0G L;  4A93 L;  4A3D L;  4A3J L;  3HOW L;  1TWC L;  4X6A L;  5IYD L;  3S2H L;  4A3B L;  3RZO L;  4A3C L;  2R7Z L;  2Y0S P;  4C3H L;  2R93 L;  4C3I L;  5IYB L;  3S1M L;  5FJ8 L;  3GTK L;  4BY7 L;  3HOY L;  3K7A L;  5FLM L;  4A3G L;  4C3J L;  3S1Q L;  3HOZ L;  5M5Y L;  2YU9 L;  3I4N L;  4A3I L;  3M4O L;  3GTQ L;  1SFO L;  2JA6 L;  3S16 L;  1I6H L;  4C2M 1;  3S15 L;  5C4J L;  4BBS L;  2PMZ P; 
#chains in the Genus database with same CATH topology
 3GTL L;  2XJQ A;  4AYB P;  3ZG6 A;  5GAD c;  2E2H L;  2QL0 A;  2E2J L;  4AHW A;  1LKM A;  3PZA A;  2AUS B;  3NFP I;  5IP9 L;  3RZ6 A;  1RB9 A;  3KYX A;  3RZD L;  1B13 A;  4WFN 1;  3H9B A;  3H99 A;  4RXN A;  2C6B A;  3LPE B;  1DVB A;  1SMM A;  3LWV B;  3LWQ B;  4AI0 A;  2DSX A;  4LHN A;  3HKZ P;  3HOV L;  3P8B A;  1P7P A;  4LHL A;  5H1S c;  4YWL A;  1C09 A;  1QCV A;  1VZI A;  2VUM L;  3S2D L;  3GTP L;  4BBR L;  4BY1 L;  3HOU L;  3GTO L;  4YWM A;  1F4L A;  1R0F A;  4A3F L;  4ZN1 B;  2EY4 E;  2A6E D;  1S2Z A;  1OWC A;  4QIW P;  1JYB A;  4TPU A;  4A3J L;  3HOW L;  1TWC L;  5IYD L;  5RXN A;  5EIN C;  4A3B L;  3RZO L;  5EIO C;  2R7Z L;  1RYT A;  2Y0S P;  4C3H L;  5IYB L;  3QQC E;  3GTK L;  1OWB A;  1ZRP A;  3HOY L;  1R0I A;  2PVX A;  1CAD A;  2PPT A;  2XJP A;  4XGH A;  2XJR A;  5MLC 3;  3I4N L;  1CAA A;  3J7Y 1;  3MSU A;  2LCQ A;  3SS2 A;  1I6H L;  4AHX A;  3FDJ A;  4XXB B;  3JR7 A;  4ME3 A;  3H3V M;  1TWH L;  3H9C A;  2B63 L;  3HAX C;  4JAG A;  1PFY A;  3S17 L;  1WCM L;  2Z3Q B;  3S1N L;  3WWL A;  4TVM A;  2WAQ P;  2XJT A;  1R9T L;  3GTG L;  1SMW A;  5C44 L;  4K9F A;  5IY0 A;  2XJU A;  2PYA A;  2WB1 P;  2NYD A;  2JA5 L;  1S24 A;  2MS3 A;  2ERJ A;  5C4X L;  2B5I D;  2CKC A;  1TWA L;  2H12 A;  3PO2 L;  4AR6 A;  2JA8 L;  1IU5 A;  1RDV A;  1YUX A;  5K2M E;  3HOX L;  2GMG A;  3LWR B;  1PFV A;  5M3M L;  1LKO A;  3RZT A;  5AI3 A;  5DM7 1;  3VPB E;  1I3Q L;  2JI1 A;  3FKI L;  2NVT L;  2K2D A;  1K83 L;  3GTJ L;  1LKP A;  5JVH 1;  4A93 L;  2V0E A;  2JI2 A;  1YUZ A;  2C6A A;  1Z92 B;  4BY7 L;  4A3G L;  3MQK B;  3HOZ L;  5GAE c;  4A3I L;  1E8J A;  3GTQ L;  1R0H A;  3H97 A;  3IU3 I;  4POF A;  4C2M 1;  5C4J L;  5GAG c;  4BBS L;  1B71 A;  5M3F L;  1VZH A;  3PWF A;  4AR5 A;  2RDV A;  3HJW B;  2Z3R B;  3QVD A;  1R0J A;  5IYC L;  7RXN A;  1PZX A;  3KYY A;  2RFK B;  4AR3 A;  1RYQ A;  3CQZ L;  1NNQ A;  3LWP B;  1I50 L;  1SMU A;  5IP7 L;  3A44 A;  3B0A B;  3GTM L;  3KYU A;  3J7Z 1;  4B8C D;  3LWO B;  2AQC A;  1S30 A;  1WJV A;  1T9P A;  2A68 D;  1YK5 A;  4A3K L;  2CKA A;  1BRF A;  1PFU A;  3PKI A;  1T9Q A;  1NXE A;  3PKJ A;  1VZG A;  1BFY A;  4AI2 A;  3I4M L;  3H0G L;  4POG A;  1BQ9 A;  1LTL A;  2XJS A;  4X6A L;  3PL5 A;  2A69 D;  3S2H L;  4V19 6;  3HJY B;  4A3C L;  2M4V A;  4AHY A;  2ERS A;  2R93 L;  2JI3 A;  1IRN A;  2L0Z A;  4AI1 A;  3S1M L;  2BE5 D;  5FLM L;  4G6B A;  2PSM C;  5MF6 A;  5DM6 1;  1IW7 D;  2ZIX A;  5MFZ A;  3M4O L;  1IU6 A;  2J9U B;  5GAH c;  2KN9 A;  3PIO 1;  1SFO L;  3S16 L;  3S15 L;  2M4Y A;  1VCX A;  2E2I L;  8RXN A;  2VL6 A;  4BXX L;  2HVY C;  4Y52 L;  1DX8 A;  2V3B B;  2NVX L;  3MPS A;  3S1R L;  3KYV A;  4U67 1;  4A3L L;  1BQ8 A;  4AR4 A;  4GS7 D;  5M5W L;  1H7V A;  3KYW A;  5AN9 H;  1ODH A;  5C3E L;  5AI2 A;  4JAD A;  2NVY L;  4JAE A;  1YK4 A;  2R92 L;  2XJV A;  3S14 L;  3PO3 L;  1Y1V L;  3B08 B;  2JA7 L;  2NVQ L;  5JVG 1;  4Y7N L;  1Y1W L;  1YV1 A;  2AYJ A;  3M3Y L;  4AI3 A;  5M5X L;  4A3E L;  1TWG L;  1RDG A;  1FHH A;  3RYG A;  1TWF L;  4A3M L;  6RXN A;  1RWD A;  2KKD A;  1R0G A;  4E6Y A;  2HR5 A;  1QYB A;  4A3D L;  1FHM A;  5MGN A;  1IRO A;  2M6P A;  2M6O A;  3WWN B;  4C3I L;  4JAF A;  4AHZ A;  1PFW A;  5FJ8 L;  1T9O A;  3K7A L;  3PIP 1;  4C3J L;  3S1Q L;  1NXG A;  2PVE A;  4UY8 1;  2APO B;  5M5Y L;  2YU9 L;  1B2O A;  3LNL A;  2O5J D;  2A6H D;  3K35 A;  2V0F A;  1B2J A;  1BE7 A;  4ZN3 B;  1QQT A;  2JA6 L;  2CR8 A;  3P2A A;  5MFP A;  2PMZ P; 
#chains in the Genus database with same CATH homology
 2E2I L;  5M3F L;  3GTL L;  4BXX L;  4Y52 L;  3H3V M;  1TWH L;  4AYB P;  2B63 L;  2E2H L;  2E2J L;  2NVX L;  3S1R L;  3S17 L;  4A3L L;  1WCM L;  5IP9 L;  3S1N L;  5IYC L;  3RZD L;  5M5W L;  2WAQ P;  1R9T L;  3GTG L;  5C44 L;  5C3E L;  2NVY L;  2WB1 P;  2JA5 L;  2R92 L;  3CQZ L;  1I50 L;  5IP7 L;  3GTM L;  5C4X L;  1TWA L;  3HKZ P;  3S14 L;  3HOV L;  3PO3 L;  3PO2 L;  2JA8 L;  1Y1V L;  2VUM L;  2JA7 L;  2NVQ L;  3S2D L;  4Y7N L;  3GTP L;  1Y1W L;  3HOX L;  4BBR L;  4BY1 L;  3HOU L;  3GTO L;  3M3Y L;  5M5X L;  4A3K L;  4A3E L;  1TWG L;  4A3F L;  5M3M L;  1TWF L;  4A3M L;  1I3Q L;  3FKI L;  2NVT L;  3I4M L;  4QIW P;  1K83 L;  3GTJ L;  3H0G L;  4A93 L;  4A3D L;  4A3J L;  3HOW L;  1TWC L;  4X6A L;  5IYD L;  3S2H L;  4A3B L;  3RZO L;  4A3C L;  2R7Z L;  2Y0S P;  4C3H L;  2R93 L;  4C3I L;  5IYB L;  3S1M L;  5FJ8 L;  3GTK L;  4BY7 L;  3HOY L;  3K7A L;  5FLM L;  4A3G L;  4C3J L;  3S1Q L;  3HOZ L;  5M5Y L;  2YU9 L;  3I4N L;  4A3I L;  3M4O L;  3GTQ L;  1SFO L;  2JA6 L;  3S16 L;  1I6H L;  4C2M 1;  3S15 L;  5C4J L;  4BBS L;  2PMZ P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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