1TWAL

Rna polymerase ii complexed with atp
Total Genus 0
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
0
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase II largest subunit
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2004-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 1twaL00
2VUML 5IYDL 2R7ZL 3M4OL 4AYBP 3I4NL 1R9TL 3GTML 3CQZL 1K83L 3K7AL 2YU9L 3S1QL 3HOZL 5M3FL 2JA5L 3S1ML 1TWCL 3M3YL 4A3KL 3GTJL 2JA8L 5IYCL 4BBSL 4BXXL 2R92L 3GTOL 5M5XL 5C4XL 4C3HL 4A3JL 5M5WL 3GTQL 2WAQP 1TWGL 3S1RL 2WB1P 3FKIL 3HOUL 4BY1L 5IP9L 4A3GL 3HOVL 4A3EL 4A3DL 3GTKL 2PMZP 5IP7L 4C2M1 3GTGL 1I6HL 3HOYL 2JA7L 5M3ML 3S2HL 2E2IL 4A93L 3HOXL 4C3JL 3H3VM 1TWAL 2R93L 4Y7NL 4A3FL 3S2DL 1I3QL 4BY7L 3GTPL 2B63L 4A3BL 1Y1VL 4A3CL 3S17L 5C3EL 2NVXL 2E2HL 5FLML 2Y0SP 4C3IL 5FJ8L 3GTLL 4A3LL 3RZDL 4Y52L 5IYBL 5C4JL 1TWHL 3S15L 1SFOL 4X6AL 4QIWP 4A3ML 3PO3L 5M5YL 1WCML 3S1NL 1TWFL 3RZOL 3HKZP 3I4ML 3PO2L 3S16L 4BBRL 2JA6L 1I50L 2NVYL 4A3IL 5C44L 2NVQL 3H0GL 3HOWL 3S14L 1Y1WL 2NVTL 2E2JL
chains in the Genus database with same CATH superfamily
4WFN1 2VL6A 3LWPB 5MF6A 1CADA 1F4LA 1DX8A 1NNQA 3M4OL 3HAXC 1IROA 1LKOA 7RXNA 1FHHA 3HOZL 3IU3I 4ME3A 2CKAA 1TWCL 3M3YL 3GTJL 1IW7D 3KYVA 4GS7D 3ZG6A 5M5XL 5C4XL 5M5WL 1BQ8A 4AR3A 3GTQL 2QL0A 2C6BA 4V196 1R0IA 3FKIL 6RXNA 1PFYA 1IU6A 1OWBA 1QQTA 1BE7A 1QYBA 1SMUA 1JYBA 4A3EL 4A3DL 4AR5A 4C2M1 2RFKB 3WWLA 1LKMA 2JA7L 3KYYA 2Z3RB 4A93L 4C3JL 5AN9H 1T9OA 2R93L 4Y7NL 5AI3A 4A3FL 3PZAA 4XXBB 4A3BL 3H97A 3MPSA 3P2AA 1NXGA 5EINC 2E2HL 2XJPA 5FLML 2H12A 2Y0SP 5GADc 4UY81 4A3LL 2PPTA 3S15L 4A3ML 3PKJA 1WCML 5M5YL 2V0FA 2XJRA 2LCQA 4ZN3B 1S2ZA 4YWMA 3HKZP 3I4ML 3H9CA 4BBRL 1I50L 3FDJA 3KYWA 1B2OA 5C44L 8RXNA 1SMWA 2O5JD 4JAEA 4LHNA 3RZ6A 1H7VA 3NFPI 4JADA 1T9PA 4AYBP 1K83L 3K7AL 5M3FL 2JA5L 2XJUA 1S24A 2XJVA 4G6BA 2DSXA 2JA8L 2KN9A 3HJYB 5DM71 4TPUA 5IYCL 2K2DA 4B8CD 3P8BA 4C3HL 1SMMA 2WAQP 4RXNA 1TWGL 4ZN1B 1PZXA 3HOUL 1IRNA 3PWFA 3K35A 1DVBA 2AQCA 4A3GL 1ZRPA 2JI3A 2PMZP 3RYGA 1I6HL 5EIOC 3HOYL 1BQ9A 5M3ML 3QVDA 2E2IL 2A6ED 2M4YA 1QCVA 2A68D 4AI3A 2PSMC 3A44A 1PFWA 4BY7L 1I3QL 1T9QA 3GTPL 1R0FA 1Y1VL 1PFVA 3HJWB 2A69D 1YUXA 1LKPA 1RWDA 1VZIA 3RZDL 2JI2A 4Y52L 3WWNB 2AYJA 3RZTA 5C4JL 2PVXA 1TWHL 1SFOL 1BFYA 4AR6A 2L0ZA 1TWFL 2B5ID 4XGHA 1RDVA 3PO2L 2NYDA 2NVYL 4A3IL 3KYUA 2NVQL 4AR4A 2NVTL 2E2JL 1R0HA 5IYDL 2R7ZL 2HR5A 2ERJA 2XJQA 4LHLA 3CQZL 4AHWA 4JAGA 1YK5A 1Z92B 3S1ML 2BE5D 3J7Y1 3PKIA 3PIP1 5MLC3 5GAEc 1YV1A 2R92L 3GTOL 1C09A 2M6PA 4A3JL 3MQKB 2XJSA 1R0JA 3S1RL 1YUZA 2XJTA 1BRFA 4BY1L 1P7PA 2HVYC 3LWVB 3GTKL 5IP7L 2PVEA 3S2HL 5RXNA 1IU5A 4JAFA 2APOB 3HOXL 4U671 1RB9A 3H3VM 5MGNA 3JR7A 5MFPA 5GAHc 3S2DL 1B71A 2GMGA 2PYAA 1CAAA 2M6OA 2C6AA 3S17L 5C3EL 4AI2A 4YWLA 3LPEB 2CKCA 3H99A 4C3IL 4TVMA 3QQCE 5IYBL 3PO3L 3H9BA 1S30A 1R0GA 1WJVA 2ERSA 3RZOL 3J7Z1 2J9UB 1RDGA 2JA6L 1RYTA 2AUSB 5MFZA 1B13A 3HOWL 3S14L 4POFA 2VUML 3I4NL 1R9TL 1ODHA 2CR8A 3VPBE 3GTML 2YU9L 3S1QL 4K9FA 1RYQA 1OWCA 3SS2A 3LWQB 3LNLA 1E8JA 4A3KL 5GAGc 1PFUA 4AHZA 2Z3QB 4BBSL 3PL5A 4BXXL 3LWOB 3B0AB 1YK4A 2ZIXA 3LWRB 2WB1P 5IY0A 2MS3A 1VCXA 3B08B 4E6YA 1VZHA 1LTLA 5IP9L 3HOVL 1NXEA 3GTGL 4AHYA 3KYXA 4AI0A 3MSUA 4AHXA 1TWAL 2A6HD 2JI1A 2B63L 1FHMA 4A3CL 2EY4E 2NVXL 5H1Sc 3PIO1 5DM61 5FJ8L 1VZGA 5K2ME 3GTLL 2KKDA 2V0EA 2M4VA 2RDVA 4X6AL 4QIWP 3S1NL 5JVG1 4AI1A 5JVH1 2V3BB 3S16L 4POGA 1B2JA 3H0GL 1Y1WL 5AI2A
chains in the Genus database with same CATH topology
2VUML 5IYDL 2R7ZL 3M4OL 4AYBP 3I4NL 1R9TL 3GTML 3CQZL 1K83L 3K7AL 2YU9L 3S1QL 3HOZL 5M3FL 2JA5L 3S1ML 1TWCL 3M3YL 4A3KL 3GTJL 2JA8L 5IYCL 4BBSL 4BXXL 2R92L 3GTOL 5M5XL 5C4XL 4C3HL 4A3JL 5M5WL 3GTQL 2WAQP 1TWGL 3S1RL 2WB1P 3FKIL 3HOUL 4BY1L 5IP9L 4A3GL 3HOVL 4A3EL 4A3DL 3GTKL 2PMZP 5IP7L 4C2M1 3GTGL 1I6HL 3HOYL 2JA7L 5M3ML 3S2HL 2E2IL 4A93L 3HOXL 4C3JL 3H3VM 1TWAL 2R93L 4Y7NL 4A3FL 3S2DL 1I3QL 4BY7L 3GTPL 2B63L 4A3BL 1Y1VL 4A3CL 3S17L 5C3EL 2NVXL 2E2HL 5FLML 2Y0SP 4C3IL 5FJ8L 3GTLL 4A3LL 3RZDL 4Y52L 5IYBL 5C4JL 1TWHL 3S15L 1SFOL 4X6AL 4QIWP 4A3ML 3PO3L 5M5YL 1WCML 3S1NL 1TWFL 3RZOL 3HKZP 3I4ML 3PO2L 3S16L 4BBRL 2JA6L 1I50L 2NVYL 4A3IL 5C44L 2NVQL 3H0GL 3HOWL 3S14L 1Y1WL 2NVTL 2E2JL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VUM L;  5IYD L;  2R7Z L;  3M4O L;  4AYB P;  3I4N L;  1R9T L;  3GTM L;  3CQZ L;  1K83 L;  3K7A L;  2YU9 L;  3S1Q L;  3HOZ L;  5M3F L;  2JA5 L;  3S1M L;  1TWC L;  3M3Y L;  4A3K L;  3GTJ L;  2JA8 L;  5IYC L;  4BBS L;  4BXX L;  2R92 L;  3GTO L;  5M5X L;  5C4X L;  4C3H L;  4A3J L;  5M5W L;  3GTQ L;  2WAQ P;  1TWG L;  3S1R L;  2WB1 P;  3FKI L;  3HOU L;  4BY1 L;  5IP9 L;  4A3G L;  3HOV L;  4A3E L;  4A3D L;  3GTK L;  2PMZ P;  5IP7 L;  4C2M 1;  3GTG L;  1I6H L;  3HOY L;  2JA7 L;  5M3M L;  3S2H L;  2E2I L;  4A93 L;  3HOX L;  4C3J L;  3H3V M;  1TWA L;  2R93 L;  4Y7N L;  4A3F L;  3S2D L;  1I3Q L;  4BY7 L;  3GTP L;  2B63 L;  4A3B L;  1Y1V L;  4A3C L;  3S17 L;  5C3E L;  2NVX L;  2E2H L;  5FLM L;  2Y0S P;  4C3I L;  5FJ8 L;  3GTL L;  4A3L L;  3RZD L;  4Y52 L;  5IYB L;  5C4J L;  1TWH L;  3S15 L;  1SFO L;  4X6A L;  4QIW P;  4A3M L;  3PO3 L;  5M5Y L;  1WCM L;  3S1N L;  1TWF L;  3RZO L;  3HKZ P;  3I4M L;  3PO2 L;  3S16 L;  4BBR L;  2JA6 L;  1I50 L;  2NVY L;  4A3I L;  5C44 L;  2NVQ L;  3H0G L;  3HOW L;  3S14 L;  1Y1W L;  2NVT L;  2E2J L; 
#chains in the Genus database with same CATH topology
 4WFN 1;  2VL6 A;  3LWP B;  5MF6 A;  1CAD A;  1F4L A;  1DX8 A;  1NNQ A;  3M4O L;  3HAX C;  1IRO A;  1LKO A;  7RXN A;  1FHH A;  3HOZ L;  3IU3 I;  4ME3 A;  2CKA A;  1TWC L;  3M3Y L;  3GTJ L;  1IW7 D;  3KYV A;  4GS7 D;  3ZG6 A;  5M5X L;  5C4X L;  5M5W L;  1BQ8 A;  4AR3 A;  3GTQ L;  2QL0 A;  2C6B A;  4V19 6;  1R0I A;  3FKI L;  6RXN A;  1PFY A;  1IU6 A;  1OWB A;  1QQT A;  1BE7 A;  1QYB A;  1SMU A;  1JYB A;  4A3E L;  4A3D L;  4AR5 A;  4C2M 1;  2RFK B;  3WWL A;  1LKM A;  2JA7 L;  3KYY A;  2Z3R B;  4A93 L;  4C3J L;  5AN9 H;  1T9O A;  2R93 L;  4Y7N L;  5AI3 A;  4A3F L;  3PZA A;  4XXB B;  4A3B L;  3H97 A;  3MPS A;  3P2A A;  1NXG A;  5EIN C;  2E2H L;  2XJP A;  5FLM L;  2H12 A;  2Y0S P;  5GAD c;  4UY8 1;  4A3L L;  2PPT A;  3S15 L;  4A3M L;  3PKJ A;  1WCM L;  5M5Y L;  2V0F A;  2XJR A;  2LCQ A;  4ZN3 B;  1S2Z A;  4YWM A;  3HKZ P;  3I4M L;  3H9C A;  4BBR L;  1I50 L;  3FDJ A;  3KYW A;  1B2O A;  5C44 L;  8RXN A;  1SMW A;  2O5J D;  4JAE A;  4LHN A;  3RZ6 A;  1H7V A;  3NFP I;  4JAD A;  1T9P A;  4AYB P;  1K83 L;  3K7A L;  5M3F L;  2JA5 L;  2XJU A;  1S24 A;  2XJV A;  4G6B A;  2DSX A;  2JA8 L;  2KN9 A;  3HJY B;  5DM7 1;  4TPU A;  5IYC L;  2K2D A;  4B8C D;  3P8B A;  4C3H L;  1SMM A;  2WAQ P;  4RXN A;  1TWG L;  4ZN1 B;  1PZX A;  3HOU L;  1IRN A;  3PWF A;  3K35 A;  1DVB A;  2AQC A;  4A3G L;  1ZRP A;  2JI3 A;  2PMZ P;  3RYG A;  1I6H L;  5EIO C;  3HOY L;  1BQ9 A;  5M3M L;  3QVD A;  2E2I L;  2A6E D;  2M4Y A;  1QCV A;  2A68 D;  4AI3 A;  2PSM C;  3A44 A;  1PFW A;  4BY7 L;  1I3Q L;  1T9Q A;  3GTP L;  1R0F A;  1Y1V L;  1PFV A;  3HJW B;  2A69 D;  1YUX A;  1LKP A;  1RWD A;  1VZI A;  3RZD L;  2JI2 A;  4Y52 L;  3WWN B;  2AYJ A;  3RZT A;  5C4J L;  2PVX A;  1TWH L;  1SFO L;  1BFY A;  4AR6 A;  2L0Z A;  1TWF L;  2B5I D;  4XGH A;  1RDV A;  3PO2 L;  2NYD A;  2NVY L;  4A3I L;  3KYU A;  2NVQ L;  4AR4 A;  2NVT L;  2E2J L;  1R0H A;  5IYD L;  2R7Z L;  2HR5 A;  2ERJ A;  2XJQ A;  4LHL A;  3CQZ L;  4AHW A;  4JAG A;  1YK5 A;  1Z92 B;  3S1M L;  2BE5 D;  3J7Y 1;  3PKI A;  3PIP 1;  5MLC 3;  5GAE c;  1YV1 A;  2R92 L;  3GTO L;  1C09 A;  2M6P A;  4A3J L;  3MQK B;  2XJS A;  1R0J A;  3S1R L;  1YUZ A;  2XJT A;  1BRF A;  4BY1 L;  1P7P A;  2HVY C;  3LWV B;  3GTK L;  5IP7 L;  2PVE A;  3S2H L;  5RXN A;  1IU5 A;  4JAF A;  2APO B;  3HOX L;  4U67 1;  1RB9 A;  3H3V M;  5MGN A;  3JR7 A;  5MFP A;  5GAH c;  3S2D L;  1B71 A;  2GMG A;  2PYA A;  1CAA A;  2M6O A;  2C6A A;  3S17 L;  5C3E L;  4AI2 A;  4YWL A;  3LPE B;  2CKC A;  3H99 A;  4C3I L;  4TVM A;  3QQC E;  5IYB L;  3PO3 L;  3H9B A;  1S30 A;  1R0G A;  1WJV A;  2ERS A;  3RZO L;  3J7Z 1;  2J9U B;  1RDG A;  2JA6 L;  1RYT A;  2AUS B;  5MFZ A;  1B13 A;  3HOW L;  3S14 L;  4POF A;  2VUM L;  3I4N L;  1R9T L;  1ODH A;  2CR8 A;  3VPB E;  3GTM L;  2YU9 L;  3S1Q L;  4K9F A;  1RYQ A;  1OWC A;  3SS2 A;  3LWQ B;  3LNL A;  1E8J A;  4A3K L;  5GAG c;  1PFU A;  4AHZ A;  2Z3Q B;  4BBS L;  3PL5 A;  4BXX L;  3LWO B;  3B0A B;  1YK4 A;  2ZIX A;  3LWR B;  2WB1 P;  5IY0 A;  2MS3 A;  1VCX A;  3B08 B;  4E6Y A;  1VZH A;  1LTL A;  5IP9 L;  3HOV L;  1NXE A;  3GTG L;  4AHY A;  3KYX A;  4AI0 A;  3MSU A;  4AHX A;  1TWA L;  2A6H D;  2JI1 A;  2B63 L;  1FHM A;  4A3C L;  2EY4 E;  2NVX L;  5H1S c;  3PIO 1;  5DM6 1;  5FJ8 L;  1VZG A;  5K2M E;  3GTL L;  2KKD A;  2V0E A;  2M4V A;  2RDV A;  4X6A L;  4QIW P;  3S1N L;  5JVG 1;  4AI1 A;  5JVH 1;  2V3B B;  3S16 L;  4POG A;  1B2J A;  3H0G L;  1Y1W L;  5AI2 A; 
#chains in the Genus database with same CATH homology
 2VUM L;  5IYD L;  2R7Z L;  3M4O L;  4AYB P;  3I4N L;  1R9T L;  3GTM L;  3CQZ L;  1K83 L;  3K7A L;  2YU9 L;  3S1Q L;  3HOZ L;  5M3F L;  2JA5 L;  3S1M L;  1TWC L;  3M3Y L;  4A3K L;  3GTJ L;  2JA8 L;  5IYC L;  4BBS L;  4BXX L;  2R92 L;  3GTO L;  5M5X L;  5C4X L;  4C3H L;  4A3J L;  5M5W L;  3GTQ L;  2WAQ P;  1TWG L;  3S1R L;  2WB1 P;  3FKI L;  3HOU L;  4BY1 L;  5IP9 L;  4A3G L;  3HOV L;  4A3E L;  4A3D L;  3GTK L;  2PMZ P;  5IP7 L;  4C2M 1;  3GTG L;  1I6H L;  3HOY L;  2JA7 L;  5M3M L;  3S2H L;  2E2I L;  4A93 L;  3HOX L;  4C3J L;  3H3V M;  1TWA L;  2R93 L;  4Y7N L;  4A3F L;  3S2D L;  1I3Q L;  4BY7 L;  3GTP L;  2B63 L;  4A3B L;  1Y1V L;  4A3C L;  3S17 L;  5C3E L;  2NVX L;  2E2H L;  5FLM L;  2Y0S P;  4C3I L;  5FJ8 L;  3GTL L;  4A3L L;  3RZD L;  4Y52 L;  5IYB L;  5C4J L;  1TWH L;  3S15 L;  1SFO L;  4X6A L;  4QIW P;  4A3M L;  3PO3 L;  5M5Y L;  1WCM L;  3S1N L;  1TWF L;  3RZO L;  3HKZ P;  3I4M L;  3PO2 L;  3S16 L;  4BBR L;  2JA6 L;  1I50 L;  2NVY L;  4A3I L;  5C44 L;  2NVQ L;  3H0G L;  3HOW L;  3S14 L;  1Y1W L;  2NVT L;  2E2J L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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