1TWFL

Rna polymerase ii complexed with utp at 2.3 a resolution
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase II largest subunit
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2004-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 1twfL00
2NVYL 1I6HL 3S14L 3HOUL 4A3JL 2NVQL 3S1RL 2E2IL 1TWFL 4A93L 1K83L 3HOXL 3S15L 4A3LL 5C44L 3S1NL 2NVXL 4X6AL 4Y52L 1WCML 3S2HL 2E2HL 2E2JL 4A3BL 5FJ8L 3K7AL 5IP7L 4A3ML 5M3FL 2R92L 5C3EL 1TWAL 1Y1VL 4A3DL 1SFOL 3GTJL 4BY7L 4A3GL 3HKZP 3HOVL 3S2DL 1R9TL 5M5XL 4AYBP 3GTLL 3I4ML 3S16L 3RZDL 3S1ML 3S1QL 2R7ZL 3I4NL 5IP9L 1I50L 5IYCL 4A3KL 5C4XL 5IYBL 4BY1L 4C3JL 2Y0SP 3S17L 3H0GL 4A3IL 5M5WL 3HOZL 3PO2L 1I3QL 3M3YL 3GTKL 4C3HL 5C4JL 2R93L 5M5YL 2JA8L 3HOYL 4BXXL 1TWHL 3GTML 5M3ML 2WAQP 3H3VM 5IYDL 2YU9L 3RZOL 3GTOL 2JA6L 1TWCL 2VUML 2JA7L 4A3EL 4A3CL 5FLML 4BBRL 3GTGL 3CQZL 3FKIL 4C3IL 3M4OL 3PO3L 2JA5L 2B63L 4BBSL 2WB1P 4C2M1 4QIWP 1Y1WL 3GTQL 4A3FL 2NVTL 2PMZP 1TWGL 3GTPL 3HOWL 4Y7NL
chains in the Genus database with same CATH superfamily
2BE5D 3HJYB 2XJTA 4TVMA 3S14L 3P2AA 5IY0A 3S1RL 3LWRB 4A93L 3KYWA 1BE7A 2LCQA 2A68D 4B8CD 1BQ9A 1F4LA 4LHNA 1BQ8A 1PZXA 2HVYC 2DSXA 2XJSA 1R0GA 3S2HL 4A3BL 2CKCA 4UY81 4ME3A 4A3ML 4JAFA 5C3EL 2XJRA 1R0HA 1Y1VL 3H99A 2Z3QB 1VCXA 1LKPA 3RZTA 5AI3A 2O5JD 2AQCA 2JI2A 4AYBP 3GTLL 1ZRPA 2PSMC 3PKJA 3RZDL 2L0ZA 3S1QL 2R7ZL 2CR8A 2PYAA 5IYCL 3K35A 2RFKB 4AI3A 2AYJA 1SMUA 1BFYA 4A3IL 1VZHA 4JAGA 1QYBA 3M3YL 3GTKL 5EINC 3PIP1 4C3HL 5M5YL 5AI2A 3GTML 5M3ML 4G6BA 2VL6A 1JYBA 3GTOL 2XJUA 1FHHA 2VUML 2JA7L 2AUSB 3CQZL 4RXNA 1LKOA 2JA5L 1NXEA 1R0FA 4AHXA 1IU5A 4C2M1 2JI1A 2PMZP 1TWGL 3PIO1 1NNQA 3HOWL 1S2ZA 3WWNB 1QCVA 2C6BA 1RDGA 1T9PA 3HOUL 4A3JL 3SS2A 2PPTA 5GAEc 1QQTA 1RB9A 5DM61 2NVXL 4Y52L 1YUZA 3K7AL 4K9FA 4AI0A 5M3FL 1YK5A 4ZN3B 2ERSA 1SFOL 4TPUA 3KYXA 3HOVL 3S2DL 1YK4A 1E8JA 5GADc 1IROA 3PWFA 3S16L 4XXBB 2RDVA 3LWQB 3I4NL 2C6AA 1I50L 1P7PA 5C4XL 5IYBL 3S17L 2PVXA 5H1Sc 1YV1A 3MPSA 2MS3A 5C4JL 7RXNA 4BXXL 1TWHL 4YWLA 5DM71 3VPBE 2YU9L 3RZOL 2V0FA 1OWBA 1LTLA 5K2ME 2M4VA 4AR4A 4A3EL 4A3CL 8RXNA 5GAGc 4POGA 2A6HD 3HJWB 1IRNA 3JR7A 2ZIXA 4QIWP 1S24A 3GTQL 1S30A 3PKIA 2XJQA 1RDVA 3KYYA 1R0IA 2XJVA 4JAEA 3IU3I 1R0JA 4XGHA 1SMMA 3LPEB 3ZG6A 2NVQL 1LKMA 4GS7D 5GAHc 3B0AB 4AI2A 2EY4E 4LHLA 1T9OA 3LWVB 1RYQA 4A3LL 3RZ6A 1FHMA 5C44L 1DVBA 4U671 2J9UB 1WCML 2E2HL 2E2JL 3LWPB 1CAAA 5FJ8L 3H9CA 2JI3A 3RYGA 4E6YA 5JVH1 4BY7L 4A3GL 3HKZP 1BRFA 2H12A 1R9TL 2HR5A 5M5XL 5IP9L 1VZIA 5MGNA 3WWLA 3FDJA 3NFPI 1IW7D 3KYUA 1NXGA 5M5WL 3HOZL 3PO2L 5EIOC 1I3QL 2R93L 2JA8L 3HOYL 5MFZA 2KKDA 3H3VM 3QVDA 3MSUA 3QQCE 1B71A 4BBRL 3M4OL 4POFA 1PFUA 1SMWA 1VZGA 1PFVA 4BBSL 2WB1P 1Y1WL 4A3FL 2NVTL 3J7Y1 4AHYA 1B13A 1IU6A 4AI1A 3GTPL 2A6ED 2B5ID 2NVYL 1Z92B 2M4YA 1I6HL 2M6PA 1WJVA 2V3BB 4AR3A 3PZAA 2E2IL 1TWFL 1C09A 1RWDA 1K83L 3HOXL 4YWMA 5MLC3 4V196 1B2JA 4JADA 3S15L 1RYTA 3LWOB 5JVG1 3B08B 3S1NL 4X6AL 2QL0A 1ODHA 6RXNA 3PL5A 3H97A 3KYVA 5IP7L 4AHWA 4AHZA 4AR5A 2R92L 1TWAL 4ZN1B 4A3DL 3GTJL 5MFPA 4WFN1 1PFYA 3J7Z1 4AR6A 1T9QA 3MQKB 3I4ML 3A44A 3S1ML 2V0EA 4A3KL 2K2DA 4BY1L 4C3JL 2Y0SP 3H0GL 2ERJA 2GMGA 2APOB 1PFWA 5RXNA 1DX8A 1H7VA 3LNLA 1OWCA 1YUXA 2WAQP 2CKAA 5IYDL 2XJPA 5MF6A 3P8BA 2JA6L 1TWCL 2A69D 5FLML 3GTGL 4C3IL 3FKIL 1CADA 2NYDA 2PVEA 3PO3L 3H9BA 2B63L 1B2OA 5AN9H 2M6OA 2Z3RB 3HAXC 4Y7NL 2KN9A
chains in the Genus database with same CATH topology
2NVYL 1I6HL 3S14L 3HOUL 4A3JL 2NVQL 3S1RL 2E2IL 1TWFL 4A93L 1K83L 3HOXL 3S15L 4A3LL 5C44L 3S1NL 2NVXL 4X6AL 4Y52L 1WCML 3S2HL 2E2HL 2E2JL 4A3BL 5FJ8L 3K7AL 5IP7L 4A3ML 5M3FL 2R92L 5C3EL 1TWAL 1Y1VL 4A3DL 1SFOL 3GTJL 4BY7L 4A3GL 3HKZP 3HOVL 3S2DL 1R9TL 5M5XL 4AYBP 3GTLL 3I4ML 3S16L 3RZDL 3S1ML 3S1QL 2R7ZL 3I4NL 5IP9L 1I50L 5IYCL 4A3KL 5C4XL 5IYBL 4BY1L 4C3JL 2Y0SP 3S17L 3H0GL 4A3IL 5M5WL 3HOZL 3PO2L 1I3QL 3M3YL 3GTKL 4C3HL 5C4JL 2R93L 5M5YL 2JA8L 3HOYL 4BXXL 1TWHL 3GTML 5M3ML 2WAQP 3H3VM 5IYDL 2YU9L 3RZOL 3GTOL 2JA6L 1TWCL 2VUML 2JA7L 4A3EL 4A3CL 5FLML 4BBRL 3GTGL 3CQZL 3FKIL 4C3IL 3M4OL 3PO3L 2JA5L 2B63L 4BBSL 2WB1P 4C2M1 4QIWP 1Y1WL 3GTQL 4A3FL 2NVTL 2PMZP 1TWGL 3GTPL 3HOWL 4Y7NL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NVY L;  1I6H L;  3S14 L;  3HOU L;  4A3J L;  2NVQ L;  3S1R L;  2E2I L;  1TWF L;  4A93 L;  1K83 L;  3HOX L;  3S15 L;  4A3L L;  5C44 L;  3S1N L;  2NVX L;  4X6A L;  4Y52 L;  1WCM L;  3S2H L;  2E2H L;  2E2J L;  4A3B L;  5FJ8 L;  3K7A L;  5IP7 L;  4A3M L;  5M3F L;  2R92 L;  5C3E L;  1TWA L;  1Y1V L;  4A3D L;  1SFO L;  3GTJ L;  4BY7 L;  4A3G L;  3HKZ P;  3HOV L;  3S2D L;  1R9T L;  5M5X L;  4AYB P;  3GTL L;  3I4M L;  3S16 L;  3RZD L;  3S1M L;  3S1Q L;  2R7Z L;  3I4N L;  5IP9 L;  1I50 L;  5IYC L;  4A3K L;  5C4X L;  5IYB L;  4BY1 L;  4C3J L;  2Y0S P;  3S17 L;  3H0G L;  4A3I L;  5M5W L;  3HOZ L;  3PO2 L;  1I3Q L;  3M3Y L;  3GTK L;  4C3H L;  5C4J L;  2R93 L;  5M5Y L;  2JA8 L;  3HOY L;  4BXX L;  1TWH L;  3GTM L;  5M3M L;  2WAQ P;  3H3V M;  5IYD L;  2YU9 L;  3RZO L;  3GTO L;  2JA6 L;  1TWC L;  2VUM L;  2JA7 L;  4A3E L;  4A3C L;  5FLM L;  4BBR L;  3GTG L;  3CQZ L;  3FKI L;  4C3I L;  3M4O L;  3PO3 L;  2JA5 L;  2B63 L;  4BBS L;  2WB1 P;  4C2M 1;  4QIW P;  1Y1W L;  3GTQ L;  4A3F L;  2NVT L;  2PMZ P;  1TWG L;  3GTP L;  3HOW L;  4Y7N L; 
#chains in the Genus database with same CATH topology
 2BE5 D;  3HJY B;  2XJT A;  4TVM A;  3S14 L;  3P2A A;  5IY0 A;  3S1R L;  3LWR B;  4A93 L;  3KYW A;  1BE7 A;  2LCQ A;  2A68 D;  4B8C D;  1BQ9 A;  1F4L A;  4LHN A;  1BQ8 A;  1PZX A;  2HVY C;  2DSX A;  2XJS A;  1R0G A;  3S2H L;  4A3B L;  2CKC A;  4UY8 1;  4ME3 A;  4A3M L;  4JAF A;  5C3E L;  2XJR A;  1R0H A;  1Y1V L;  3H99 A;  2Z3Q B;  1VCX A;  1LKP A;  3RZT A;  5AI3 A;  2O5J D;  2AQC A;  2JI2 A;  4AYB P;  3GTL L;  1ZRP A;  2PSM C;  3PKJ A;  3RZD L;  2L0Z A;  3S1Q L;  2R7Z L;  2CR8 A;  2PYA A;  5IYC L;  3K35 A;  2RFK B;  4AI3 A;  2AYJ A;  1SMU A;  1BFY A;  4A3I L;  1VZH A;  4JAG A;  1QYB A;  3M3Y L;  3GTK L;  5EIN C;  3PIP 1;  4C3H L;  5M5Y L;  5AI2 A;  3GTM L;  5M3M L;  4G6B A;  2VL6 A;  1JYB A;  3GTO L;  2XJU A;  1FHH A;  2VUM L;  2JA7 L;  2AUS B;  3CQZ L;  4RXN A;  1LKO A;  2JA5 L;  1NXE A;  1R0F A;  4AHX A;  1IU5 A;  4C2M 1;  2JI1 A;  2PMZ P;  1TWG L;  3PIO 1;  1NNQ A;  3HOW L;  1S2Z A;  3WWN B;  1QCV A;  2C6B A;  1RDG A;  1T9P A;  3HOU L;  4A3J L;  3SS2 A;  2PPT A;  5GAE c;  1QQT A;  1RB9 A;  5DM6 1;  2NVX L;  4Y52 L;  1YUZ A;  3K7A L;  4K9F A;  4AI0 A;  5M3F L;  1YK5 A;  4ZN3 B;  2ERS A;  1SFO L;  4TPU A;  3KYX A;  3HOV L;  3S2D L;  1YK4 A;  1E8J A;  5GAD c;  1IRO A;  3PWF A;  3S16 L;  4XXB B;  2RDV A;  3LWQ B;  3I4N L;  2C6A A;  1I50 L;  1P7P A;  5C4X L;  5IYB L;  3S17 L;  2PVX A;  5H1S c;  1YV1 A;  3MPS A;  2MS3 A;  5C4J L;  7RXN A;  4BXX L;  1TWH L;  4YWL A;  5DM7 1;  3VPB E;  2YU9 L;  3RZO L;  2V0F A;  1OWB A;  1LTL A;  5K2M E;  2M4V A;  4AR4 A;  4A3E L;  4A3C L;  8RXN A;  5GAG c;  4POG A;  2A6H D;  3HJW B;  1IRN A;  3JR7 A;  2ZIX A;  4QIW P;  1S24 A;  3GTQ L;  1S30 A;  3PKI A;  2XJQ A;  1RDV A;  3KYY A;  1R0I A;  2XJV A;  4JAE A;  3IU3 I;  1R0J A;  4XGH A;  1SMM A;  3LPE B;  3ZG6 A;  2NVQ L;  1LKM A;  4GS7 D;  5GAH c;  3B0A B;  4AI2 A;  2EY4 E;  4LHL A;  1T9O A;  3LWV B;  1RYQ A;  4A3L L;  3RZ6 A;  1FHM A;  5C44 L;  1DVB A;  4U67 1;  2J9U B;  1WCM L;  2E2H L;  2E2J L;  3LWP B;  1CAA A;  5FJ8 L;  3H9C A;  2JI3 A;  3RYG A;  4E6Y A;  5JVH 1;  4BY7 L;  4A3G L;  3HKZ P;  1BRF A;  2H12 A;  1R9T L;  2HR5 A;  5M5X L;  5IP9 L;  1VZI A;  5MGN A;  3WWL A;  3FDJ A;  3NFP I;  1IW7 D;  3KYU A;  1NXG A;  5M5W L;  3HOZ L;  3PO2 L;  5EIO C;  1I3Q L;  2R93 L;  2JA8 L;  3HOY L;  5MFZ A;  2KKD A;  3H3V M;  3QVD A;  3MSU A;  3QQC E;  1B71 A;  4BBR L;  3M4O L;  4POF A;  1PFU A;  1SMW A;  1VZG A;  1PFV A;  4BBS L;  2WB1 P;  1Y1W L;  4A3F L;  2NVT L;  3J7Y 1;  4AHY A;  1B13 A;  1IU6 A;  4AI1 A;  3GTP L;  2A6E D;  2B5I D;  2NVY L;  1Z92 B;  2M4Y A;  1I6H L;  2M6P A;  1WJV A;  2V3B B;  4AR3 A;  3PZA A;  2E2I L;  1TWF L;  1C09 A;  1RWD A;  1K83 L;  3HOX L;  4YWM A;  5MLC 3;  4V19 6;  1B2J A;  4JAD A;  3S15 L;  1RYT A;  3LWO B;  5JVG 1;  3B08 B;  3S1N L;  4X6A L;  2QL0 A;  1ODH A;  6RXN A;  3PL5 A;  3H97 A;  3KYV A;  5IP7 L;  4AHW A;  4AHZ A;  4AR5 A;  2R92 L;  1TWA L;  4ZN1 B;  4A3D L;  3GTJ L;  5MFP A;  4WFN 1;  1PFY A;  3J7Z 1;  4AR6 A;  1T9Q A;  3MQK B;  3I4M L;  3A44 A;  3S1M L;  2V0E A;  4A3K L;  2K2D A;  4BY1 L;  4C3J L;  2Y0S P;  3H0G L;  2ERJ A;  2GMG A;  2APO B;  1PFW A;  5RXN A;  1DX8 A;  1H7V A;  3LNL A;  1OWC A;  1YUX A;  2WAQ P;  2CKA A;  5IYD L;  2XJP A;  5MF6 A;  3P8B A;  2JA6 L;  1TWC L;  2A69 D;  5FLM L;  3GTG L;  4C3I L;  3FKI L;  1CAD A;  2NYD A;  2PVE A;  3PO3 L;  3H9B A;  2B63 L;  1B2O A;  5AN9 H;  2M6O A;  2Z3R B;  3HAX C;  4Y7N L;  2KN9 A; 
#chains in the Genus database with same CATH homology
 2NVY L;  1I6H L;  3S14 L;  3HOU L;  4A3J L;  2NVQ L;  3S1R L;  2E2I L;  1TWF L;  4A93 L;  1K83 L;  3HOX L;  3S15 L;  4A3L L;  5C44 L;  3S1N L;  2NVX L;  4X6A L;  4Y52 L;  1WCM L;  3S2H L;  2E2H L;  2E2J L;  4A3B L;  5FJ8 L;  3K7A L;  5IP7 L;  4A3M L;  5M3F L;  2R92 L;  5C3E L;  1TWA L;  1Y1V L;  4A3D L;  1SFO L;  3GTJ L;  4BY7 L;  4A3G L;  3HKZ P;  3HOV L;  3S2D L;  1R9T L;  5M5X L;  4AYB P;  3GTL L;  3I4M L;  3S16 L;  3RZD L;  3S1M L;  3S1Q L;  2R7Z L;  3I4N L;  5IP9 L;  1I50 L;  5IYC L;  4A3K L;  5C4X L;  5IYB L;  4BY1 L;  4C3J L;  2Y0S P;  3S17 L;  3H0G L;  4A3I L;  5M5W L;  3HOZ L;  3PO2 L;  1I3Q L;  3M3Y L;  3GTK L;  4C3H L;  5C4J L;  2R93 L;  5M5Y L;  2JA8 L;  3HOY L;  4BXX L;  1TWH L;  3GTM L;  5M3M L;  2WAQ P;  3H3V M;  5IYD L;  2YU9 L;  3RZO L;  3GTO L;  2JA6 L;  1TWC L;  2VUM L;  2JA7 L;  4A3E L;  4A3C L;  5FLM L;  4BBR L;  3GTG L;  3CQZ L;  3FKI L;  4C3I L;  3M4O L;  3PO3 L;  2JA5 L;  2B63 L;  4BBS L;  2WB1 P;  4C2M 1;  4QIW P;  1Y1W L;  3GTQ L;  4A3F L;  2NVT L;  2PMZ P;  1TWG L;  3GTP L;  3HOW L;  4Y7N L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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