1TWGL

Rna polymerase ii complexed with ctp
Total Genus 0
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
0
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase II largest subunit
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2004-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 1twgL00
5IYCL 3PO2L 2NVQL 2Y0SP 4BY7L 3HOZL 3S16L 4A3ML 4A3JL 3HKZP 4BBRL 3S1NL 2PMZP 1TWCL 3GTLL 2YU9L 1K83L 4BBSL 2JA6L 3S17L 4A3DL 4Y52L 5FLML 3GTJL 1TWHL 4C3JL 4A3CL 4A3BL 5C3EL 2JA8L 1TWGL 3GTGL 3HOYL 2B63L 2NVTL 1WCML 2R7ZL 2WAQP 4A3GL 4BXXL 3GTQL 2JA5L 3HOXL 3K7AL 4Y7NL 3M4OL 3H3VM 2E2HL 3S15L 3PO3L 1R9TL 4A3IL 3GTKL 3S2HL 4BY1L 3S2DL 3CQZL 5IP9L 1I6HL 3S1ML 3GTML 5IYDL 2WB1P 5M3FL 4C3HL 4AYBP 4X6AL 3GTOL 5C4JL 4C3IL 1I3QL 5IYBL 4QIWP 2JA7L 5M5XL 5C44L 5M5WL 1SFOL 2NVYL 2NVXL 4C2M1 3RZOL 1I50L 1TWAL 3HOWL 3HOUL 5M3ML 5IP7L 3H0GL 3I4ML 4A3KL 2R92L 3M3YL 4A3FL 1Y1WL 2E2IL 2R93L 4A3LL 5FJ8L 3S1QL 5C4XL 4A93L 3FKIL 1TWFL 4A3EL 2VUML 3HOVL 3GTPL 3S14L 2E2JL 3S1RL 3RZDL 1Y1VL 3I4NL 5M5YL
chains in the Genus database with same CATH superfamily
5IYCL 4AHXA 3PO2L 2VL6A 1K83L 2XJSA 4Y52L 5FLML 2Z3QB 3GTJL 3H9BA 5C3EL 2A69D 2C6AA 3GTGL 4AR4A 2JI2A 2B63L 1YUXA 2NVTL 1DX8A 3GTQL 5JVG1 3HOXL 1NXGA 4V196 3H3VM 4POFA 3PO3L 1QYBA 2KN9A 2PVEA 1I6HL 1IRNA 2WB1P 3RZTA 2XJUA 4AR3A 4C3HL 4K9FA 3HAXC 4X6AL 1IU6A 1PFYA 2H12A 1I3QL 1R0JA 2L0ZA 5IYBL 2JA7L 1B2OA 5C44L 1BE7A 2PPTA 2AQCA 5M5WL 4G6BA 4C2M1 3RZOL 1BQ9A 3RZ6A 1B2JA 3KYUA 5IP7L 4AI0A 2K2DA 2MS3A 2KKDA 2R92L 1RYTA 1Y1WL 4AR5A 2E2IL 1P7PA 4A3LL 1JYBA 1LKOA 2XJTA 3HJYB 2VUML 4A3EL 5H1Sc 1YK5A 5GAHc 3KYYA 2A6HD 1S2ZA 1Y1VL 3ZG6A 4AI3A 1VZGA 5AI3A 2EY4E 5GAEc 3NFPI 1E8JA 4BY7L 1WJVA 5IY0A 3S16L 4A3JL 1BQ8A 4BBRL 2AYJA 2V0EA 5EINC 2GMGA 3S17L 3P2AA 2AUSB 2QL0A 3LNLA 1YUZA 1TWHL 3J7Y1 4A3CL 4A3BL 2PYAA 3PWFA 1TWGL 2JA8L 2RDVA 4AI2A 3LWOB 2R7ZL 2WAQP 2JA5L 1SMUA 2PVXA 3K7AL 3M4OL 3S15L 1R9TL 3LWPB 4A3IL 3GTKL 1QCVA 2ERJA 3WWLA 1T9PA 4BY1L 4AHZA 1CADA 3GTML 3PKIA 5IYDL 1T9OA 5M3FL 5JVH1 2JI3A 4B8CD 1ODHA 1PZXA 3LWQB 3GTOL 4C3IL 1NXEA 4POGA 3SS2A 5M5XL 3FDJA 3KYWA 4AHWA 5RXNA 5MF6A 5AN9H 1NNQA 2M4VA 5MFZA 4RXNA 1ZRPA 3H9CA 2PSMC 3HOUL 3PZAA 1FHHA 1RDVA 3H0GL 4ZN1B 1T9QA 5GADc 1LKMA 3MQKB 4XGHA 3FKIL 3HOVL 2M6PA 1B71A 3GTPL 4AI1A 2RFKB 1QQTA 3RZDL 3S1RL 2A68D 1S30A 4A93L 1VCXA 3QVDA 1SMMA 4A3ML 3HKZP 3S1NL 2V0FA 3GTLL 3B08B 2HVYC 5DM61 1RB9A 1VZHA 4A3DL 3LWRB 1PFWA 4C3JL 1PFVA 1B13A 1YK4A 4U671 5MLC3 4AR6A 3HOYL 2CKAA 2XJRA 4ZN3B 3PL5A 4LHNA 2E2HL 3PKJA 1R0GA 5MGNA 5DM71 4ME3A 3CQZL 3WWNB 2A6ED 1IROA 4AYBP 1RDGA 4WFN1 4QIWP 4XXBB 2M4YA 1OWBA 4LHLA 2ERSA 6RXNA 2O5JD 2NVYL 2NVXL 1RYQA 1I50L 1TWAL 1CAAA 1LKPA 3I4ML 4A3KL 2XJVA 3M3YL 4AHYA 1Z92B 2R93L 2ZIXA 3H97A 3S1QL 3KYXA 3IU3I 1TWFL 1R0HA 3S14L 2E2JL 3MPSA 5AI2A 3HJWB 2XJQA 3JR7A 1PFUA 4JAGA 2NVQL 2Y0SP 3MSUA 4GS7D 3LWVB 3HOZL 2J9UB 1VZIA 2HR5A 1H7VA 2PMZP 1TWCL 1R0IA 2YU9L 4BBSL 2JA6L 2C6BA 2NYDA 1BFYA 3PIO1 2JI1A 5GAGc 4TVMA 1R0FA 2V3BB 7RXNA 1WCML 4A3GL 2CR8A 4BXXL 2M6OA 4JAFA 3A44A 4Y7NL 1F4LA 3S2HL 3QQCE 2Z3RB 3S2DL 5IP9L 5EIOC 3S1ML 5MFPA 3P8BA 1S24A 4JADA 3K35A 1BRFA 5C4JL 3VPBE 1IW7D 1IU5A 2B5ID 8RXNA 2LCQA 3B0AB 4E6YA 4YWLA 1SFOL 1C09A 1SMWA 2CKCA 4JAEA 3HOWL 5K2ME 5M3ML 3PIP1 3H99A 1FHMA 1RWDA 2XJPA 4A3FL 4YWMA 2DSXA 4UY81 5FJ8L 1DVBA 2BE5D 1YV1A 5C4XL 3J7Z1 3RYGA 3LPEB 3KYVA 1OWCA 1LTLA 3I4NL 2APOB 5M5YL 4TPUA
chains in the Genus database with same CATH topology
5IYCL 3PO2L 2NVQL 2Y0SP 4BY7L 3HOZL 3S16L 4A3ML 4A3JL 3HKZP 4BBRL 3S1NL 2PMZP 1TWCL 3GTLL 2YU9L 1K83L 4BBSL 2JA6L 3S17L 4A3DL 4Y52L 5FLML 3GTJL 1TWHL 4C3JL 4A3CL 4A3BL 5C3EL 2JA8L 1TWGL 3GTGL 3HOYL 2B63L 2NVTL 1WCML 2R7ZL 2WAQP 4A3GL 4BXXL 3GTQL 2JA5L 3HOXL 3K7AL 4Y7NL 3M4OL 3H3VM 2E2HL 3S15L 3PO3L 1R9TL 4A3IL 3GTKL 3S2HL 4BY1L 3S2DL 3CQZL 5IP9L 1I6HL 3S1ML 3GTML 5IYDL 2WB1P 5M3FL 4C3HL 4AYBP 4X6AL 3GTOL 5C4JL 4C3IL 1I3QL 5IYBL 4QIWP 2JA7L 5M5XL 5C44L 5M5WL 1SFOL 2NVYL 2NVXL 4C2M1 3RZOL 1I50L 1TWAL 3HOWL 3HOUL 5M3ML 5IP7L 3H0GL 3I4ML 4A3KL 2R92L 3M3YL 4A3FL 1Y1WL 2E2IL 2R93L 4A3LL 5FJ8L 3S1QL 5C4XL 4A93L 3FKIL 1TWFL 4A3EL 2VUML 3HOVL 3GTPL 3S14L 2E2JL 3S1RL 3RZDL 1Y1VL 3I4NL 5M5YL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IYC L;  3PO2 L;  2NVQ L;  2Y0S P;  4BY7 L;  3HOZ L;  3S16 L;  4A3M L;  4A3J L;  3HKZ P;  4BBR L;  3S1N L;  2PMZ P;  1TWC L;  3GTL L;  2YU9 L;  1K83 L;  4BBS L;  2JA6 L;  3S17 L;  4A3D L;  4Y52 L;  5FLM L;  3GTJ L;  1TWH L;  4C3J L;  4A3C L;  4A3B L;  5C3E L;  2JA8 L;  1TWG L;  3GTG L;  3HOY L;  2B63 L;  2NVT L;  1WCM L;  2R7Z L;  2WAQ P;  4A3G L;  4BXX L;  3GTQ L;  2JA5 L;  3HOX L;  3K7A L;  4Y7N L;  3M4O L;  3H3V M;  2E2H L;  3S15 L;  3PO3 L;  1R9T L;  4A3I L;  3GTK L;  3S2H L;  4BY1 L;  3S2D L;  3CQZ L;  5IP9 L;  1I6H L;  3S1M L;  3GTM L;  5IYD L;  2WB1 P;  5M3F L;  4C3H L;  4AYB P;  4X6A L;  3GTO L;  5C4J L;  4C3I L;  1I3Q L;  5IYB L;  4QIW P;  2JA7 L;  5M5X L;  5C44 L;  5M5W L;  1SFO L;  2NVY L;  2NVX L;  4C2M 1;  3RZO L;  1I50 L;  1TWA L;  3HOW L;  3HOU L;  5M3M L;  5IP7 L;  3H0G L;  3I4M L;  4A3K L;  2R92 L;  3M3Y L;  4A3F L;  1Y1W L;  2E2I L;  2R93 L;  4A3L L;  5FJ8 L;  3S1Q L;  5C4X L;  4A93 L;  3FKI L;  1TWF L;  4A3E L;  2VUM L;  3HOV L;  3GTP L;  3S14 L;  2E2J L;  3S1R L;  3RZD L;  1Y1V L;  3I4N L;  5M5Y L; 
#chains in the Genus database with same CATH topology
 5IYC L;  4AHX A;  3PO2 L;  2VL6 A;  1K83 L;  2XJS A;  4Y52 L;  5FLM L;  2Z3Q B;  3GTJ L;  3H9B A;  5C3E L;  2A69 D;  2C6A A;  3GTG L;  4AR4 A;  2JI2 A;  2B63 L;  1YUX A;  2NVT L;  1DX8 A;  3GTQ L;  5JVG 1;  3HOX L;  1NXG A;  4V19 6;  3H3V M;  4POF A;  3PO3 L;  1QYB A;  2KN9 A;  2PVE A;  1I6H L;  1IRN A;  2WB1 P;  3RZT A;  2XJU A;  4AR3 A;  4C3H L;  4K9F A;  3HAX C;  4X6A L;  1IU6 A;  1PFY A;  2H12 A;  1I3Q L;  1R0J A;  2L0Z A;  5IYB L;  2JA7 L;  1B2O A;  5C44 L;  1BE7 A;  2PPT A;  2AQC A;  5M5W L;  4G6B A;  4C2M 1;  3RZO L;  1BQ9 A;  3RZ6 A;  1B2J A;  3KYU A;  5IP7 L;  4AI0 A;  2K2D A;  2MS3 A;  2KKD A;  2R92 L;  1RYT A;  1Y1W L;  4AR5 A;  2E2I L;  1P7P A;  4A3L L;  1JYB A;  1LKO A;  2XJT A;  3HJY B;  2VUM L;  4A3E L;  5H1S c;  1YK5 A;  5GAH c;  3KYY A;  2A6H D;  1S2Z A;  1Y1V L;  3ZG6 A;  4AI3 A;  1VZG A;  5AI3 A;  2EY4 E;  5GAE c;  3NFP I;  1E8J A;  4BY7 L;  1WJV A;  5IY0 A;  3S16 L;  4A3J L;  1BQ8 A;  4BBR L;  2AYJ A;  2V0E A;  5EIN C;  2GMG A;  3S17 L;  3P2A A;  2AUS B;  2QL0 A;  3LNL A;  1YUZ A;  1TWH L;  3J7Y 1;  4A3C L;  4A3B L;  2PYA A;  3PWF A;  1TWG L;  2JA8 L;  2RDV A;  4AI2 A;  3LWO B;  2R7Z L;  2WAQ P;  2JA5 L;  1SMU A;  2PVX A;  3K7A L;  3M4O L;  3S15 L;  1R9T L;  3LWP B;  4A3I L;  3GTK L;  1QCV A;  2ERJ A;  3WWL A;  1T9P A;  4BY1 L;  4AHZ A;  1CAD A;  3GTM L;  3PKI A;  5IYD L;  1T9O A;  5M3F L;  5JVH 1;  2JI3 A;  4B8C D;  1ODH A;  1PZX A;  3LWQ B;  3GTO L;  4C3I L;  1NXE A;  4POG A;  3SS2 A;  5M5X L;  3FDJ A;  3KYW A;  4AHW A;  5RXN A;  5MF6 A;  5AN9 H;  1NNQ A;  2M4V A;  5MFZ A;  4RXN A;  1ZRP A;  3H9C A;  2PSM C;  3HOU L;  3PZA A;  1FHH A;  1RDV A;  3H0G L;  4ZN1 B;  1T9Q A;  5GAD c;  1LKM A;  3MQK B;  4XGH A;  3FKI L;  3HOV L;  2M6P A;  1B71 A;  3GTP L;  4AI1 A;  2RFK B;  1QQT A;  3RZD L;  3S1R L;  2A68 D;  1S30 A;  4A93 L;  1VCX A;  3QVD A;  1SMM A;  4A3M L;  3HKZ P;  3S1N L;  2V0F A;  3GTL L;  3B08 B;  2HVY C;  5DM6 1;  1RB9 A;  1VZH A;  4A3D L;  3LWR B;  1PFW A;  4C3J L;  1PFV A;  1B13 A;  1YK4 A;  4U67 1;  5MLC 3;  4AR6 A;  3HOY L;  2CKA A;  2XJR A;  4ZN3 B;  3PL5 A;  4LHN A;  2E2H L;  3PKJ A;  1R0G A;  5MGN A;  5DM7 1;  4ME3 A;  3CQZ L;  3WWN B;  2A6E D;  1IRO A;  4AYB P;  1RDG A;  4WFN 1;  4QIW P;  4XXB B;  2M4Y A;  1OWB A;  4LHL A;  2ERS A;  6RXN A;  2O5J D;  2NVY L;  2NVX L;  1RYQ A;  1I50 L;  1TWA L;  1CAA A;  1LKP A;  3I4M L;  4A3K L;  2XJV A;  3M3Y L;  4AHY A;  1Z92 B;  2R93 L;  2ZIX A;  3H97 A;  3S1Q L;  3KYX A;  3IU3 I;  1TWF L;  1R0H A;  3S14 L;  2E2J L;  3MPS A;  5AI2 A;  3HJW B;  2XJQ A;  3JR7 A;  1PFU A;  4JAG A;  2NVQ L;  2Y0S P;  3MSU A;  4GS7 D;  3LWV B;  3HOZ L;  2J9U B;  1VZI A;  2HR5 A;  1H7V A;  2PMZ P;  1TWC L;  1R0I A;  2YU9 L;  4BBS L;  2JA6 L;  2C6B A;  2NYD A;  1BFY A;  3PIO 1;  2JI1 A;  5GAG c;  4TVM A;  1R0F A;  2V3B B;  7RXN A;  1WCM L;  4A3G L;  2CR8 A;  4BXX L;  2M6O A;  4JAF A;  3A44 A;  4Y7N L;  1F4L A;  3S2H L;  3QQC E;  2Z3R B;  3S2D L;  5IP9 L;  5EIO C;  3S1M L;  5MFP A;  3P8B A;  1S24 A;  4JAD A;  3K35 A;  1BRF A;  5C4J L;  3VPB E;  1IW7 D;  1IU5 A;  2B5I D;  8RXN A;  2LCQ A;  3B0A B;  4E6Y A;  4YWL A;  1SFO L;  1C09 A;  1SMW A;  2CKC A;  4JAE A;  3HOW L;  5K2M E;  5M3M L;  3PIP 1;  3H99 A;  1FHM A;  1RWD A;  2XJP A;  4A3F L;  4YWM A;  2DSX A;  4UY8 1;  5FJ8 L;  1DVB A;  2BE5 D;  1YV1 A;  5C4X L;  3J7Z 1;  3RYG A;  3LPE B;  3KYV A;  1OWC A;  1LTL A;  3I4N L;  2APO B;  5M5Y L;  4TPU A; 
#chains in the Genus database with same CATH homology
 5IYC L;  3PO2 L;  2NVQ L;  2Y0S P;  4BY7 L;  3HOZ L;  3S16 L;  4A3M L;  4A3J L;  3HKZ P;  4BBR L;  3S1N L;  2PMZ P;  1TWC L;  3GTL L;  2YU9 L;  1K83 L;  4BBS L;  2JA6 L;  3S17 L;  4A3D L;  4Y52 L;  5FLM L;  3GTJ L;  1TWH L;  4C3J L;  4A3C L;  4A3B L;  5C3E L;  2JA8 L;  1TWG L;  3GTG L;  3HOY L;  2B63 L;  2NVT L;  1WCM L;  2R7Z L;  2WAQ P;  4A3G L;  4BXX L;  3GTQ L;  2JA5 L;  3HOX L;  3K7A L;  4Y7N L;  3M4O L;  3H3V M;  2E2H L;  3S15 L;  3PO3 L;  1R9T L;  4A3I L;  3GTK L;  3S2H L;  4BY1 L;  3S2D L;  3CQZ L;  5IP9 L;  1I6H L;  3S1M L;  3GTM L;  5IYD L;  2WB1 P;  5M3F L;  4C3H L;  4AYB P;  4X6A L;  3GTO L;  5C4J L;  4C3I L;  1I3Q L;  5IYB L;  4QIW P;  2JA7 L;  5M5X L;  5C44 L;  5M5W L;  1SFO L;  2NVY L;  2NVX L;  4C2M 1;  3RZO L;  1I50 L;  1TWA L;  3HOW L;  3HOU L;  5M3M L;  5IP7 L;  3H0G L;  3I4M L;  4A3K L;  2R92 L;  3M3Y L;  4A3F L;  1Y1W L;  2E2I L;  2R93 L;  4A3L L;  5FJ8 L;  3S1Q L;  5C4X L;  4A93 L;  3FKI L;  1TWF L;  4A3E L;  2VUM L;  3HOV L;  3GTP L;  3S14 L;  2E2J L;  3S1R L;  3RZD L;  1Y1V L;  3I4N L;  5M5Y L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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