1WARA

Recombinant human purple acid phosphatase expressed in pichia pastoris
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
310
structure length
310
Chain Sequence
EAEAEFATPALRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQILGADFILSLGDNFYFTGVQDINDKRFQETFEDVFSDRSLRKVPWYVLAGNHDHLGNVSAQIAYSKISKRWNFPSPFYRLHFKIPQTNVSVAIFMLDTVTLCGNSDDFLSQQPERPRDVKLARTQLSWLKKQLAAAREDYVLVAGHYPVWSIAEHGPTHCLVKQLRPLLATYGVTAYLCGHDHNLQYLQDENGVGYVLSGAGNFMDPSKRHQRKVPNGYLRFHYGTEDSLGGFAYVEISSKEMTVTYIEASGKSLFKTRLPRRARP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Recombinant Human Purple Acid Phosphatase with and without an Inhibitory Conformation of the Repression Loop.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords HUMAN PURPLE ACID PHOSPHATASE
total genus 109
structure length 310
sequence length 310
ec nomenclature ec 3.1.3.2: Acid phosphatase.
pdb deposition date 2004-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 1warA00
1V73A 4TUGA 1Z2WA 4LTYA 2DFJA 4JA9A 2HYPA 1IT6A 3RL5A 2JOGA 3PSOA 3QFMA 3K7WC 1FJMA 3QFKA 5INBA 3P71C 5DNYA 2BDXA 3IB7A 5F3WA 4H2FA 3IVEA 4LU9A 3H61A 4O24A 1S95A 4FBQA 2YVTA 4UT3A 3PSNA 3DSCA 1HO5A 1S70A 4DHLA 4XPNA 3IB8A 5JJTA 1S3LA 1TCOA 4IYPC 1S3MA 2USHA 1S3NA 1HP1A 3DW8C 3E7AA 3GVEA 4H2IA 2KKNA 1WARA 2NYMC 2Q8UA 1G5BA 4DSYA 3ZTVA 4V0VA 5C1VA 2IAEC 1USHA 4B2OA 2Z72A 2WDCA 5J28A 1QFCA 2HY1A 3K7VC 1QHWA 4MP0A 2A22A 4O5GA 1XZWA 4MOYA 3FGAC 3HVQA 1HPUA 3KBPA 1Z2XA 2HYOA 3V4YA 4KBPA 3IVDA 4V0XA 3RQZA 3N5UA 3H68A 4ZVZA 2O8GA 2R17A 3EGGA 5B8IA 4IL1A 4LACC 1OIDA 2ZBMA 3THNA 4KKZA 3QFNA 4O4KA 4V0WA 4Q7FA 4WWLA 1KBPA 3T1IA 2BQ8X 1U32A 3RL4A 3ZU0A 3H60A 2P6BA 4DT2A 1XM7A 2BCDA 1M63A 1UTEA 4I5NC 3H66A 3TGHA 2AHDA 1II7A 4O43A 5EQVA 1OIEA 4UT3B 3EGHA 2WDDA 4JA7A 1WAO1 4ORAA 3C5WC 3RL3A 4H1SA 2QFRA 4MOVA 1UF3A 2O8AA 1W24A 2IE4C 2NXFA 2NYLC 5HPEA 5JPFA 2Z1AA 3DSDA 3H69A 4G9JA 4NZVA 4UT2A 4FBKA 3QFOA 1T71A 1AUIA 2NPPC 2WDFA 3H67A 2Z06A 4FBWA 4H2BA 1MF8A 3C9FA 3LL8A 4ZX2A 1OI8A 4OR9A 3E7BA 2XMOA 4ORCA 4H2GA 2WDEA 4YKEA 3AUZA 3CK2A 2GJUA 1T70A 1SU1A 4TUIA 4I5LC 3ICFA 4H1YP 3JYFA 1NNWA 1JK7A 1S8EA 3THOB 4ORBA 2CV9A 2QJCA 2IE3C 4FCXA 5IOHA 4M0VA 2QFPA 3AV0A 4J6OA 5JPEA 4HD0A 3H64A 3H63A 5GTUA 3H62B 4UWQA 3QG5C 4F0ZA
chains in the Genus database with same CATH superfamily
1V73A 4TUGA 1Z2WA 4LTYA 2DFJA 4JA9A 2HYPA 1IT6A 3RL5A 2JOGA 3PSOA 3QFMA 3K7WC 1FJMA 3QFKA 5INBA 3P71C 3E0JA 5DNYA 2BDXA 3IB7A 5F3WA 4H2FA 3IVEA 4LU9A 2YEQA 3H61A 4O24A 1S95A 4FBQA 2YVTA 4UT3A 2DXNA 3PSNA 3DSCA 1HO5A 1S70A 4DHLA 4XPNA 3IB8A 5JJTA 1S3LA 1TCOA 4IYPC 1S3MA 2USHA 1S3NA 1HP1A 2ZO9B 3DW8C 3E7AA 3GVEA 4H2IA 2KKNA 1WARA 3FLOA 2NYMC 2Q8UA 1G5BA 4DSYA 3ZTVA 4V0VA 5C1VA 2IAEC 1USHA 4B2OA 2Z72A 2WDCA 5J28A 1QFCA 2HY1A 3K7VC 1QHWA 4MP0A 2A22A 4O5GA 1XZWA 4MOYA 3FGAC 3HVQA 1HPUA 3KBPA 1Z2XA 2HYOA 3V4YA 4KBPA 3IVDA 4V0XA 3RQZA 3N5UA 3H68A 4ZVZA 2DXLA 2O8GA 2R17A 3EGGA 5B8IA 4IL1A 4LACC 1OIDA 2ZBMA 3THNA 4KKZA 3QFNA 4O4KA 4V0WA 4Q7FA 4WWLA 1KBPA 3T1IA 2BQ8X 1U32A 3RL4A 3ZU0A 3H60A 2P6BA 4DT2A 1XM7A 2BCDA 1M63A 1UTEA 4I5NC 3H66A 3TGHA 2AHDA 1II7A 4O43A 5EQVA 1OIEA 4UT3B 3EGHA 2WDDA 4JA7A 1WAO1 4ORAA 3C5WC 3RL3A 4H1SA 2QFRA 4MOVA 1UF3A 2O8AA 1W24A 2IE4C 2NXFA 2NYLC 5HPEA 5JPFA 2Z1AA 2ZOAA 3DSDA 3H69A 4G9JA 4NZVA 4UT2A 4FBKA 3QFOA 1T71A 1AUIA 2NPPC 2WDFA 3H67A 2Z06A 4FBWA 4H2BA 1MF8A 3C9FA 3LL8A 4ZX2A 1OI8A 3D03A 4OR9A 3E7BA 2XMOA 4ORCA 4H2GA 2WDEA 4YKEA 3AUZA 3CK2A 2GJUA 1T70A 1SU1A 4TUIA 4I5LC 3ICFA 4H1YP 3JYFA 1NNWA 1JK7A 1S8EA 3THOB 4ORBA 2CV9A 2QJCA 2IE3C 4FCXA 5IOHA 4M0VA 2QFPA 3AV0A 4J6OA 5JPEA 4HD0A 3H64A 3H63A 5GTUA 3H62B 4UWQA 3QG5C 4F0ZA
chains in the Genus database with same CATH topology
1V73A 4TUGA 1Z2WA 4LTYA 2DFJA 4JA9A 2HYPA 1IT6A 3RL5A 2JOGA 3PSOA 3QFMA 3K7WC 1FJMA 3QFKA 5INBA 3P71C 3E0JA 5DNYA 2BDXA 3IB7A 5F3WA 4H2FA 3IVEA 4LU9A 2YEQA 3H61A 4O24A 1S95A 4FBQA 2YVTA 4UT3A 2DXNA 3PSNA 3DSCA 1HO5A 1S70A 4DHLA 4XPNA 3IB8A 5JJTA 1S3LA 1TCOA 4IYPC 1S3MA 2USHA 1S3NA 1HP1A 2ZO9B 3DW8C 3E7AA 3GVEA 4H2IA 2KKNA 1WARA 3FLOA 2NYMC 2Q8UA 1G5BA 4DSYA 3ZTVA 4V0VA 5C1VA 2IAEC 1USHA 4B2OA 2Z72A 2WDCA 5J28A 1QFCA 2HY1A 3K7VC 1QHWA 4MP0A 2A22A 4O5GA 1XZWA 4MOYA 3FGAC 3HVQA 1HPUA 3KBPA 1Z2XA 2HYOA 3V4YA 4KBPA 3IVDA 4V0XA 3RQZA 3N5UA 3H68A 4ZVZA 2DXLA 2O8GA 2R17A 3EGGA 5B8IA 4IL1A 4LACC 1OIDA 2ZBMA 3THNA 4KKZA 3QFNA 4O4KA 4V0WA 4Q7FA 4WWLA 1KBPA 3T1IA 2BQ8X 1U32A 3RL4A 3ZU0A 3H60A 2P6BA 4DT2A 1XM7A 2BCDA 1M63A 1UTEA 4I5NC 3H66A 3TGHA 2AHDA 1II7A 4O43A 5EQVA 1OIEA 4UT3B 3EGHA 2WDDA 4JA7A 1WAO1 4ORAA 3C5WC 3RL3A 4H1SA 2QFRA 4MOVA 1UF3A 2O8AA 1W24A 2IE4C 2NXFA 2NYLC 5HPEA 5JPFA 2Z1AA 2ZOAA 3DSDA 3H69A 4G9JA 4NZVA 4UT2A 4FBKA 3QFOA 1T71A 1AUIA 2NPPC 2WDFA 3H67A 2Z06A 4FBWA 4H2BA 1MF8A 3C9FA 3LL8A 4ZX2A 1OI8A 3D03A 4OR9A 3E7BA 2XMOA 4ORCA 4H2GA 2WDEA 4YKEA 3AUZA 3CK2A 2GJUA 1T70A 1SU1A 4TUIA 4I5LC 3ICFA 4H1YP 3JYFA 1NNWA 1JK7A 1S8EA 3THOB 4ORBA 2CV9A 2QJCA 2IE3C 4FCXA 5IOHA 4M0VA 2QFPA 3AV0A 4J6OA 5JPEA 4HD0A 3H64A 3H63A 5GTUA 3H62B 4UWQA 3QG5C 4F0ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1V73 A;  4TUG A;  1Z2W A;  4LTY A;  2DFJ A;  4JA9 A;  2HYP A;  1IT6 A;  3RL5 A;  2JOG A;  3PSO A;  3QFM A;  3K7W C;  1FJM A;  3QFK A;  5INB A;  3P71 C;  5DNY A;  2BDX A;  3IB7 A;  5F3W A;  4H2F A;  3IVE A;  4LU9 A;  3H61 A;  4O24 A;  1S95 A;  4FBQ A;  2YVT A;  4UT3 A;  3PSN A;  3DSC A;  1HO5 A;  1S70 A;  4DHL A;  4XPN A;  3IB8 A;  5JJT A;  1S3L A;  1TCO A;  4IYP C;  1S3M A;  2USH A;  1S3N A;  1HP1 A;  3DW8 C;  3E7A A;  3GVE A;  4H2I A;  2KKN A;  1WAR A;  2NYM C;  2Q8U A;  1G5B A;  4DSY A;  3ZTV A;  4V0V A;  5C1V A;  2IAE C;  1USH A;  4B2O A;  2Z72 A;  2WDC A;  5J28 A;  1QFC A;  2HY1 A;  3K7V C;  1QHW A;  4MP0 A;  2A22 A;  4O5G A;  1XZW A;  4MOY A;  3FGA C;  3HVQ A;  1HPU A;  3KBP A;  1Z2X A;  2HYO A;  3V4Y A;  4KBP A;  3IVD A;  4V0X A;  3RQZ A;  3N5U A;  3H68 A;  4ZVZ A;  2O8G A;  2R17 A;  3EGG A;  5B8I A;  4IL1 A;  4LAC C;  1OID A;  2ZBM A;  3THN A;  4KKZ A;  3QFN A;  4O4K A;  4V0W A;  4Q7F A;  4WWL A;  1KBP A;  3T1I A;  2BQ8 X;  1U32 A;  3RL4 A;  3ZU0 A;  3H60 A;  2P6B A;  4DT2 A;  1XM7 A;  2BCD A;  1M63 A;  1UTE A;  4I5N C;  3H66 A;  3TGH A;  2AHD A;  1II7 A;  4O43 A;  5EQV A;  1OIE A;  4UT3 B;  3EGH A;  2WDD A;  4JA7 A;  1WAO 1;  4ORA A;  3C5W C;  3RL3 A;  4H1S A;  2QFR A;  4MOV A;  1UF3 A;  2O8A A;  1W24 A;  2IE4 C;  2NXF A;  2NYL C;  5HPE A;  5JPF A;  2Z1A A;  3DSD A;  3H69 A;  4G9J A;  4NZV A;  4UT2 A;  4FBK A;  3QFO A;  1T71 A;  1AUI A;  2NPP C;  2WDF A;  3H67 A;  2Z06 A;  4FBW A;  4H2B A;  1MF8 A;  3C9F A;  3LL8 A;  4ZX2 A;  1OI8 A;  4OR9 A;  3E7B A;  2XMO A;  4ORC A;  4H2G A;  2WDE A;  4YKE A;  3AUZ A;  3CK2 A;  2GJU A;  1T70 A;  1SU1 A;  4TUI A;  4I5L C;  3ICF A;  4H1Y P;  3JYF A;  1NNW A;  1JK7 A;  1S8E A;  3THO B;  4ORB A;  2CV9 A;  2QJC A;  2IE3 C;  4FCX A;  5IOH A;  4M0V A;  2QFP A;  3AV0 A;  4J6O A;  5JPE A;  4HD0 A;  3H64 A;  3H63 A;  5GTU A;  3H62 B;  4UWQ A;  3QG5 C;  4F0Z A; 
#chains in the Genus database with same CATH topology
 1V73 A;  4TUG A;  1Z2W A;  4LTY A;  2DFJ A;  4JA9 A;  2HYP A;  1IT6 A;  3RL5 A;  2JOG A;  3PSO A;  3QFM A;  3K7W C;  1FJM A;  3QFK A;  5INB A;  3P71 C;  3E0J A;  5DNY A;  2BDX A;  3IB7 A;  5F3W A;  4H2F A;  3IVE A;  4LU9 A;  2YEQ A;  3H61 A;  4O24 A;  1S95 A;  4FBQ A;  2YVT A;  4UT3 A;  2DXN A;  3PSN A;  3DSC A;  1HO5 A;  1S70 A;  4DHL A;  4XPN A;  3IB8 A;  5JJT A;  1S3L A;  1TCO A;  4IYP C;  1S3M A;  2USH A;  1S3N A;  1HP1 A;  2ZO9 B;  3DW8 C;  3E7A A;  3GVE A;  4H2I A;  2KKN A;  1WAR A;  3FLO A;  2NYM C;  2Q8U A;  1G5B A;  4DSY A;  3ZTV A;  4V0V A;  5C1V A;  2IAE C;  1USH A;  4B2O A;  2Z72 A;  2WDC A;  5J28 A;  1QFC A;  2HY1 A;  3K7V C;  1QHW A;  4MP0 A;  2A22 A;  4O5G A;  1XZW A;  4MOY A;  3FGA C;  3HVQ A;  1HPU A;  3KBP A;  1Z2X A;  2HYO A;  3V4Y A;  4KBP A;  3IVD A;  4V0X A;  3RQZ A;  3N5U A;  3H68 A;  4ZVZ A;  2DXL A;  2O8G A;  2R17 A;  3EGG A;  5B8I A;  4IL1 A;  4LAC C;  1OID A;  2ZBM A;  3THN A;  4KKZ A;  3QFN A;  4O4K A;  4V0W A;  4Q7F A;  4WWL A;  1KBP A;  3T1I A;  2BQ8 X;  1U32 A;  3RL4 A;  3ZU0 A;  3H60 A;  2P6B A;  4DT2 A;  1XM7 A;  2BCD A;  1M63 A;  1UTE A;  4I5N C;  3H66 A;  3TGH A;  2AHD A;  1II7 A;  4O43 A;  5EQV A;  1OIE A;  4UT3 B;  3EGH A;  2WDD A;  4JA7 A;  1WAO 1;  4ORA A;  3C5W C;  3RL3 A;  4H1S A;  2QFR A;  4MOV A;  1UF3 A;  2O8A A;  1W24 A;  2IE4 C;  2NXF A;  2NYL C;  5HPE A;  5JPF A;  2Z1A A;  2ZOA A;  3DSD A;  3H69 A;  4G9J A;  4NZV A;  4UT2 A;  4FBK A;  3QFO A;  1T71 A;  1AUI A;  2NPP C;  2WDF A;  3H67 A;  2Z06 A;  4FBW A;  4H2B A;  1MF8 A;  3C9F A;  3LL8 A;  4ZX2 A;  1OI8 A;  3D03 A;  4OR9 A;  3E7B A;  2XMO A;  4ORC A;  4H2G A;  2WDE A;  4YKE A;  3AUZ A;  3CK2 A;  2GJU A;  1T70 A;  1SU1 A;  4TUI A;  4I5L C;  3ICF A;  4H1Y P;  3JYF A;  1NNW A;  1JK7 A;  1S8E A;  3THO B;  4ORB A;  2CV9 A;  2QJC A;  2IE3 C;  4FCX A;  5IOH A;  4M0V A;  2QFP A;  3AV0 A;  4J6O A;  5JPE A;  4HD0 A;  3H64 A;  3H63 A;  5GTU A;  3H62 B;  4UWQ A;  3QG5 C;  4F0Z A; 
#chains in the Genus database with same CATH homology
 1V73 A;  4TUG A;  1Z2W A;  4LTY A;  2DFJ A;  4JA9 A;  2HYP A;  1IT6 A;  3RL5 A;  2JOG A;  3PSO A;  3QFM A;  3K7W C;  1FJM A;  3QFK A;  5INB A;  3P71 C;  3E0J A;  5DNY A;  2BDX A;  3IB7 A;  5F3W A;  4H2F A;  3IVE A;  4LU9 A;  2YEQ A;  3H61 A;  4O24 A;  1S95 A;  4FBQ A;  2YVT A;  4UT3 A;  2DXN A;  3PSN A;  3DSC A;  1HO5 A;  1S70 A;  4DHL A;  4XPN A;  3IB8 A;  5JJT A;  1S3L A;  1TCO A;  4IYP C;  1S3M A;  2USH A;  1S3N A;  1HP1 A;  2ZO9 B;  3DW8 C;  3E7A A;  3GVE A;  4H2I A;  2KKN A;  1WAR A;  3FLO A;  2NYM C;  2Q8U A;  1G5B A;  4DSY A;  3ZTV A;  4V0V A;  5C1V A;  2IAE C;  1USH A;  4B2O A;  2Z72 A;  2WDC A;  5J28 A;  1QFC A;  2HY1 A;  3K7V C;  1QHW A;  4MP0 A;  2A22 A;  4O5G A;  1XZW A;  4MOY A;  3FGA C;  3HVQ A;  1HPU A;  3KBP A;  1Z2X A;  2HYO A;  3V4Y A;  4KBP A;  3IVD A;  4V0X A;  3RQZ A;  3N5U A;  3H68 A;  4ZVZ A;  2DXL A;  2O8G A;  2R17 A;  3EGG A;  5B8I A;  4IL1 A;  4LAC C;  1OID A;  2ZBM A;  3THN A;  4KKZ A;  3QFN A;  4O4K A;  4V0W A;  4Q7F A;  4WWL A;  1KBP A;  3T1I A;  2BQ8 X;  1U32 A;  3RL4 A;  3ZU0 A;  3H60 A;  2P6B A;  4DT2 A;  1XM7 A;  2BCD A;  1M63 A;  1UTE A;  4I5N C;  3H66 A;  3TGH A;  2AHD A;  1II7 A;  4O43 A;  5EQV A;  1OIE A;  4UT3 B;  3EGH A;  2WDD A;  4JA7 A;  1WAO 1;  4ORA A;  3C5W C;  3RL3 A;  4H1S A;  2QFR A;  4MOV A;  1UF3 A;  2O8A A;  1W24 A;  2IE4 C;  2NXF A;  2NYL C;  5HPE A;  5JPF A;  2Z1A A;  2ZOA A;  3DSD A;  3H69 A;  4G9J A;  4NZV A;  4UT2 A;  4FBK A;  3QFO A;  1T71 A;  1AUI A;  2NPP C;  2WDF A;  3H67 A;  2Z06 A;  4FBW A;  4H2B A;  1MF8 A;  3C9F A;  3LL8 A;  4ZX2 A;  1OI8 A;  3D03 A;  4OR9 A;  3E7B A;  2XMO A;  4ORC A;  4H2G A;  2WDE A;  4YKE A;  3AUZ A;  3CK2 A;  2GJU A;  1T70 A;  1SU1 A;  4TUI A;  4I5L C;  3ICF A;  4H1Y P;  3JYF A;  1NNW A;  1JK7 A;  1S8E A;  3THO B;  4ORB A;  2CV9 A;  2QJC A;  2IE3 C;  4FCX A;  5IOH A;  4M0V A;  2QFP A;  3AV0 A;  4J6O A;  5JPE A;  4HD0 A;  3H64 A;  3H63 A;  5GTU A;  3H62 B;  4UWQ A;  3QG5 C;  4F0Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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