2CKAA

Solution structures of the brk domains of the human chromo helicase domain 7 and 8, reveals structural similarity with gyf domain suggesting a role in protein interaction
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
58
structure length
58
Chain Sequence
LDVDLETRIPVINKVDGTLLVGEDAPRRAELEMWLQGHPEFAVDPRFLAYMEDRRKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 8
total genus 14
structure length 58
sequence length 58
ec nomenclature ec 3.6.4.12: DNA helicase.
pdb deposition date 2006-04-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07533 BRK BRK domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.130 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2ckaA01
2V0EA 2CKCA 2CKAA 2V0FA
chains in the Genus database with same CATH superfamily
4C3JL 5DM71 3H3VM 1YUXA 1DVBA 2ERSA 4ZN1B 5C4XL 4A3EL 4A93L 3GTQL 1TWFL 2C6BA 5IYDL 2CKAA 4POGA 1TWAL 3M4OL 5GAGc 2RDVA 5MFPA 4A3LL 4JADA 5EINC 4AR6A 1FHMA 1FHHA 2B5ID 3J7Y1 2DSXA 4JAEA 2QL0A 2J9UB 5GADc 5RXNA 5MFZA 4A3FL 2NVQL 2WB1P 2B63L 1ZRPA 4AI1A 1SFOL 2A6HD 3PKJA 1QQTA 4AHWA 5EIOC 3QVDA 3LWOB 2AUSB 1H7VA 3I4NL 1IRNA 4A3JL 3LWRB 3CQZL 1CADA 1OWCA 1TWCL 2R7ZL 1RYQA 3H0GL 3A44A 2PYAA 3PO3L 1IROA 8RXNA 4BBSL 3P8BA 4QIWP 4BBRL 1PZXA 2CKCA 2A6ED 3MQKB 3KYVA 4B8CD 4YWMA 5IP7L 1NNQA 3S2DL 1S30A 3S1NL 3RYGA 4WFN1 1IW7D 2XJVA 5GAHc 4BXXL 4AI0A 1YUZA 1Z92B 1T9PA 2Y0SP 4A3GL 2XJTA 1TWHL 3RZTA 3PWFA 3B0AB 4Y52L 1PFUA 2AQCA 3HOVL 5M5XL 2EY4E 1F4LA 2PVEA 3HAXC 2HR5A 2C6AA 2E2HL 4AHXA 1QCVA 2V3BB 2VL6A 1I6HL 2JA5L 3K7AL 2PSMC 3FDJA 4LHNA 1OWBA 1E8JA 2ERJA 1K83L 5IYCL 3KYWA 4AHZA 1SMUA 1JYBA 1RWDA 1R0GA 4XGHA 3P2AA 1R0FA 1BQ8A 1RYTA 7RXNA 1C09A 1PFYA 4C3IL 5M5YL 2ZIXA 3QQCE 2PVXA 2XJPA 5GAEc 2XJRA 4BY1L 4LHLA 2WAQP 3PIP1 3KYUA 3SS2A 3H99A 3GTGL 1S2ZA 3RZDL 3H97A 1R0HA 3FKIL 3PZAA 2A68D 5AI3A 4AI3A 1LKMA 4RXNA 3RZOL 3HJYB 2CR8A 3GTOL 1LKPA 2PPTA 3HOUL 5MF6A 1RDGA 1VZIA 2GMGA 3NFPI 4A3CL 4C3HL 4A3ML 6RXNA 2LCQA 5AN9H 2JA7L 4A3KL 1YK5A 3H9CA 5JVH1 4TPUA 2MS3A 3ZG6A 2M4YA 2APOB 3S15L 4K9FA 2NVYL 1LTLA 2E2IL 3VPBE 3S1ML 2O5JD 1B2JA 1PFWA 3MSUA 1P7PA 5JVG1 5MGNA 1R9TL 3S17L 3I4ML 3K35A 3HOZL 3S2HL 3KYXA 1IU6A 3MPSA 2RFKB 1B71A 3JR7A 1BE7A 3S14L 2BE5D 1Y1VL 4YWLA 3WWNB 2M6OA 3J7Z1 2KN9A 1I3QL 2Z3RB 1SMMA 1VZGA 3S1RL 3IU3I 2M6PA 3GTLL 2JA8L 5K2ME 4X6AL 1DX8A 2K2DA 4POFA 3LWQB 3LPEB 1VCXA 2JI1A 4A3DL 2KKDA 3PL5A 1IU5A 5IP9L 4A3IL 5C3EL 2M4VA 1PFVA 2XJQA 5MLC3 1RDVA 2NVTL 2V0FA 2NVXL 4TVMA 3B08B 4AYBP 2NYDA 3HKZP 5IYBL 5IY0A 3HOWL 3PKIA 3S1QL 1VZHA 1BRFA 3HOXL 5DM61 1RB9A 5AI2A 2JI3A 1T9QA 3LWPB 4C2M1 1NXEA 1I50L 3KYYA 2YU9L 3PO2L 1YV1A 3RZ6A 3GTJL 4JAGA 1BFYA 4AR4A 1SMWA 4AR3A 4V196 1S24A 1WCML 3LNLA 2E2JL 1B2OA 5FJ8L 1R0JA 3GTML 1Y1WL 2XJSA 1YK4A 1B13A 4AHYA 2PMZP 1TWGL 2A69D 5C44L 4BY7L 4AI2A 2XJUA 4XXBB 2R92L 2Z3QB 2AYJA 2L0ZA 4JAFA 1LKOA 3PIO1 2JI2A 4G6BA 1T9OA 2V0EA 3HJWB 4A3BL 1WJVA 1R0IA 5FLML 4ZN3B 4ME3A 5M5WL 3WWLA 4E6YA 3GTKL 2JA6L 2R93L 2HVYC 2VUML 5H1Sc 4GS7D 4Y7NL 1ODHA 3HOYL 1QYBA 1CAAA 1NXGA 4U671 2H12A 4AR5A 5M3ML 3S16L 4UY81 3M3YL 3H9BA 5C4JL 5M3FL 1BQ9A 3GTPL 3LWVB
chains in the Genus database with same CATH topology
5DM71 2CR8A 1S30A 1LKPA 2PPTA 2V0FA 3RYGA 4TVMA 4WFN1 1IW7D 5MF6A 1YUXA 3B08B 1RDGA 2XJVA 5GAHc 2NYDA 1VZIA 2GMGA 5IY0A 4AI0A 1DVBA 1YUZA 2ERSA 3NFPI 1Z92B 1T9PA 3PKIA 6RXNA 1VZHA 1BRFA 2LCQA 2XJTA 1RB9A 4ZN1B 5DM61 5AN9H 3RZTA 1YK5A 3PWFA 3B0AB 5JVH1 5AI2A 2JI3A 1T9QA 4TPUA 2MS3A 2C6BA 3ZG6A 2M4YA 1NXEA 2CKAA 3KYYA 1YV1A 4K9FA 3RZ6A 4POGA 1LTLA 3VPBE 4JAGA 2PVEA 1BFYA 5GAGc 2RDVA 1B2JA 2HR5A 4AR4A 3MSUA 1SMWA 4AR3A 2C6AA 4V196 2O5JD 1S24A 5MFPA 3LNLA 4AHXA 1QCVA 4JADA 5EINC 5JVG1 5MGNA 1B2OA 3K35A 4AR6A 1FHMA 2V3BB 1IU6A 3KYXA 2VL6A 3MPSA 1B71A 1R0JA 1FHHA 2B5ID 1BE7A 3J7Y1 2DSXA 2XJSA 1YK4A 4JAEA 2PSMC 2QL0A 1B13A 4AHYA 4LHNA 2J9UB 5GADc 2BE5D 4YWLA 3WWNB 5RXNA 5MFZA 2A69D 2M6OA 4AI2A 3J7Z1 2XJUA 4XXBB 2KN9A 2Z3QB 1OWBA 1E8JA 2AYJA 2ERJA 2Z3RB 1SMMA 2L0ZA 4JAFA 1LKOA 1VZGA 1ZRPA 4AI1A 3PIO1 3KYWA 2JI2A 4G6BA 1T9OA 4AHZA 2V0EA 2A6HD 3PKJA 1SMUA 1WJVA 1R0IA 1JYBA 4AHWA 4ZN3B 5EIOC 1RWDA 3QVDA 3IU3I 2M6PA 4ME3A 1DX8A 5K2ME 3WWLA 1R0GA 4E6YA 2K2DA 4POFA 1H7VA 4XGHA 1IRNA 3P2AA 1R0FA 1BQ8A 5H1Sc 4GS7D 1RYTA 3LPEB 1C09A 7RXNA 1VCXA 1CADA 2ZIXA 3QQCE 2PVXA 2JI1A 1OWCA 2XJPA 5GAEc 2XJRA 1RYQA 1ODHA 3A44A 4LHLA 2PYAA 2KKDA 1IROA 3PIP1 1QYBA 1IU5A 3KYUA 1CAAA 1NXGA 3SS2A 4U671 8RXNA 1S2ZA 2H12A 2M4VA 4AR5A 3P8BA 2XJQA 3PZAA 1R0HA 4UY81 2A68D 2CKCA 2A6ED 5AI3A 5MLC3 3KYVA 1RDVA 4B8CD 1LKMA 4YWMA 4RXNA 1BQ9A 4AI3A 1NNQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V0E A;  2CKC A;  2CKA A;  2V0F A; 
#chains in the Genus database with same CATH topology
 4C3J L;  5DM7 1;  3H3V M;  1YUX A;  1DVB A;  2ERS A;  4ZN1 B;  5C4X L;  4A3E L;  4A93 L;  3GTQ L;  1TWF L;  2C6B A;  5IYD L;  2CKA A;  4POG A;  1TWA L;  3M4O L;  5GAG c;  2RDV A;  5MFP A;  4A3L L;  4JAD A;  5EIN C;  4AR6 A;  1FHM A;  1FHH A;  2B5I D;  3J7Y 1;  2DSX A;  4JAE A;  2QL0 A;  2J9U B;  5GAD c;  5RXN A;  5MFZ A;  4A3F L;  2NVQ L;  2WB1 P;  2B63 L;  1ZRP A;  4AI1 A;  1SFO L;  2A6H D;  3PKJ A;  1QQT A;  4AHW A;  5EIO C;  3QVD A;  3LWO B;  2AUS B;  1H7V A;  3I4N L;  1IRN A;  4A3J L;  3LWR B;  3CQZ L;  1CAD A;  1OWC A;  1TWC L;  2R7Z L;  1RYQ A;  3H0G L;  3A44 A;  2PYA A;  3PO3 L;  1IRO A;  8RXN A;  4BBS L;  3P8B A;  4QIW P;  4BBR L;  1PZX A;  2CKC A;  2A6E D;  3MQK B;  3KYV A;  4B8C D;  4YWM A;  5IP7 L;  1NNQ A;  3S2D L;  1S30 A;  3S1N L;  3RYG A;  4WFN 1;  1IW7 D;  2XJV A;  5GAH c;  4BXX L;  4AI0 A;  1YUZ A;  1Z92 B;  1T9P A;  2Y0S P;  4A3G L;  2XJT A;  1TWH L;  3RZT A;  3PWF A;  3B0A B;  4Y52 L;  1PFU A;  2AQC A;  3HOV L;  5M5X L;  2EY4 E;  1F4L A;  2PVE A;  3HAX C;  2HR5 A;  2C6A A;  2E2H L;  4AHX A;  1QCV A;  2V3B B;  2VL6 A;  1I6H L;  2JA5 L;  3K7A L;  2PSM C;  3FDJ A;  4LHN A;  1OWB A;  1E8J A;  2ERJ A;  1K83 L;  5IYC L;  3KYW A;  4AHZ A;  1SMU A;  1JYB A;  1RWD A;  1R0G A;  4XGH A;  3P2A A;  1R0F A;  1BQ8 A;  1RYT A;  7RXN A;  1C09 A;  1PFY A;  4C3I L;  5M5Y L;  2ZIX A;  3QQC E;  2PVX A;  2XJP A;  5GAE c;  2XJR A;  4BY1 L;  4LHL A;  2WAQ P;  3PIP 1;  3KYU A;  3SS2 A;  3H99 A;  3GTG L;  1S2Z A;  3RZD L;  3H97 A;  1R0H A;  3FKI L;  3PZA A;  2A68 D;  5AI3 A;  4AI3 A;  1LKM A;  4RXN A;  3RZO L;  3HJY B;  2CR8 A;  3GTO L;  1LKP A;  2PPT A;  3HOU L;  5MF6 A;  1RDG A;  1VZI A;  2GMG A;  3NFP I;  4A3C L;  4C3H L;  4A3M L;  6RXN A;  2LCQ A;  5AN9 H;  2JA7 L;  4A3K L;  1YK5 A;  3H9C A;  5JVH 1;  4TPU A;  2MS3 A;  3ZG6 A;  2M4Y A;  2APO B;  3S15 L;  4K9F A;  2NVY L;  1LTL A;  2E2I L;  3VPB E;  3S1M L;  2O5J D;  1B2J A;  1PFW A;  3MSU A;  1P7P A;  5JVG 1;  5MGN A;  1R9T L;  3S17 L;  3I4M L;  3K35 A;  3HOZ L;  3S2H L;  3KYX A;  1IU6 A;  3MPS A;  2RFK B;  1B71 A;  3JR7 A;  1BE7 A;  3S14 L;  2BE5 D;  1Y1V L;  4YWL A;  3WWN B;  2M6O A;  3J7Z 1;  2KN9 A;  1I3Q L;  2Z3R B;  1SMM A;  1VZG A;  3S1R L;  3IU3 I;  2M6P A;  3GTL L;  2JA8 L;  5K2M E;  4X6A L;  1DX8 A;  2K2D A;  4POF A;  3LWQ B;  3LPE B;  1VCX A;  2JI1 A;  4A3D L;  2KKD A;  3PL5 A;  1IU5 A;  5IP9 L;  4A3I L;  5C3E L;  2M4V A;  1PFV A;  2XJQ A;  5MLC 3;  1RDV A;  2NVT L;  2V0F A;  2NVX L;  4TVM A;  3B08 B;  4AYB P;  2NYD A;  3HKZ P;  5IYB L;  5IY0 A;  3HOW L;  3PKI A;  3S1Q L;  1VZH A;  1BRF A;  3HOX L;  5DM6 1;  1RB9 A;  5AI2 A;  2JI3 A;  1T9Q A;  3LWP B;  4C2M 1;  1NXE A;  1I50 L;  3KYY A;  2YU9 L;  3PO2 L;  1YV1 A;  3RZ6 A;  3GTJ L;  4JAG A;  1BFY A;  4AR4 A;  1SMW A;  4AR3 A;  4V19 6;  1S24 A;  1WCM L;  3LNL A;  2E2J L;  1B2O A;  5FJ8 L;  1R0J A;  3GTM L;  1Y1W L;  2XJS A;  1YK4 A;  1B13 A;  4AHY A;  2PMZ P;  1TWG L;  2A69 D;  5C44 L;  4BY7 L;  4AI2 A;  2XJU A;  4XXB B;  2R92 L;  2Z3Q B;  2AYJ A;  2L0Z A;  4JAF A;  1LKO A;  3PIO 1;  2JI2 A;  4G6B A;  1T9O A;  2V0E A;  3HJW B;  4A3B L;  1WJV A;  1R0I A;  5FLM L;  4ZN3 B;  4ME3 A;  5M5W L;  3WWL A;  4E6Y A;  3GTK L;  2JA6 L;  2R93 L;  2HVY C;  2VUM L;  5H1S c;  4GS7 D;  4Y7N L;  1ODH A;  3HOY L;  1QYB A;  1CAA A;  1NXG A;  4U67 1;  2H12 A;  4AR5 A;  5M3M L;  3S16 L;  4UY8 1;  3M3Y L;  3H9B A;  5C4J L;  5M3F L;  1BQ9 A;  3GTP L;  3LWV B; 
#chains in the Genus database with same CATH homology
 5DM7 1;  2CR8 A;  1S30 A;  1LKP A;  2PPT A;  2V0F A;  3RYG A;  4TVM A;  4WFN 1;  1IW7 D;  5MF6 A;  1YUX A;  3B08 B;  1RDG A;  2XJV A;  5GAH c;  2NYD A;  1VZI A;  2GMG A;  5IY0 A;  4AI0 A;  1DVB A;  1YUZ A;  2ERS A;  3NFP I;  1Z92 B;  1T9P A;  3PKI A;  6RXN A;  1VZH A;  1BRF A;  2LCQ A;  2XJT A;  1RB9 A;  4ZN1 B;  5DM6 1;  5AN9 H;  3RZT A;  1YK5 A;  3PWF A;  3B0A B;  5JVH 1;  5AI2 A;  2JI3 A;  1T9Q A;  4TPU A;  2MS3 A;  2C6B A;  3ZG6 A;  2M4Y A;  1NXE A;  2CKA A;  3KYY A;  1YV1 A;  4K9F A;  3RZ6 A;  4POG A;  1LTL A;  3VPB E;  4JAG A;  2PVE A;  1BFY A;  5GAG c;  2RDV A;  1B2J A;  2HR5 A;  4AR4 A;  3MSU A;  1SMW A;  4AR3 A;  2C6A A;  4V19 6;  2O5J D;  1S24 A;  5MFP A;  3LNL A;  4AHX A;  1QCV A;  4JAD A;  5EIN C;  5JVG 1;  5MGN A;  1B2O A;  3K35 A;  4AR6 A;  1FHM A;  2V3B B;  1IU6 A;  3KYX A;  2VL6 A;  3MPS A;  1B71 A;  1R0J A;  1FHH A;  2B5I D;  1BE7 A;  3J7Y 1;  2DSX A;  2XJS A;  1YK4 A;  4JAE A;  2PSM C;  2QL0 A;  1B13 A;  4AHY A;  4LHN A;  2J9U B;  5GAD c;  2BE5 D;  4YWL A;  3WWN B;  5RXN A;  5MFZ A;  2A69 D;  2M6O A;  4AI2 A;  3J7Z 1;  2XJU A;  4XXB B;  2KN9 A;  2Z3Q B;  1OWB A;  1E8J A;  2AYJ A;  2ERJ A;  2Z3R B;  1SMM A;  2L0Z A;  4JAF A;  1LKO A;  1VZG A;  1ZRP A;  4AI1 A;  3PIO 1;  3KYW A;  2JI2 A;  4G6B A;  1T9O A;  4AHZ A;  2V0E A;  2A6H D;  3PKJ A;  1SMU A;  1WJV A;  1R0I A;  1JYB A;  4AHW A;  4ZN3 B;  5EIO C;  1RWD A;  3QVD A;  3IU3 I;  2M6P A;  4ME3 A;  1DX8 A;  5K2M E;  3WWL A;  1R0G A;  4E6Y A;  2K2D A;  4POF A;  1H7V A;  4XGH A;  1IRN A;  3P2A A;  1R0F A;  1BQ8 A;  5H1S c;  4GS7 D;  1RYT A;  3LPE B;  1C09 A;  7RXN A;  1VCX A;  1CAD A;  2ZIX A;  3QQC E;  2PVX A;  2JI1 A;  1OWC A;  2XJP A;  5GAE c;  2XJR A;  1RYQ A;  1ODH A;  3A44 A;  4LHL A;  2PYA A;  2KKD A;  1IRO A;  3PIP 1;  1QYB A;  1IU5 A;  3KYU A;  1CAA A;  1NXG A;  3SS2 A;  4U67 1;  8RXN A;  1S2Z A;  2H12 A;  2M4V A;  4AR5 A;  3P8B A;  2XJQ A;  3PZA A;  1R0H A;  4UY8 1;  2A68 D;  2CKC A;  2A6E D;  5AI3 A;  5MLC 3;  3KYV A;  1RDV A;  4B8C D;  1LKM A;  4YWM A;  4RXN A;  1BQ9 A;  4AI3 A;  1NNQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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