2DFJA

Crystal structure of the diadenosine tetraphosphate hydrolase from shigella flexneri 2a
Total Genus 74
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
267
structure length
267
Chain Sequence
ATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGSLTCLRWEDKQYFVQPS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of the diadenosine tetraphosphate hydrolase from Shigella flexneri 2a
pubmed doi rcsb
molecule tags Hydrolase
source organism Shigella flexneri 2a
molecule keywords diadenosinetetraphosphatase
total genus 74
structure length 267
sequence length 267
chains with identical sequence B
ec nomenclature ec 3.6.1.41: Bis(5'-nucleosyl)-tetraphosphatase (symmetrical).
pdb deposition date 2006-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2dfjA00
2CV9A 2ZBMA 1T71A 1Z2WA 5B8IA 1OI8A 2HYPA 1QHWA 5EQVA 4HD0A 1QFCA 5GTUA 4I5NC 4DT2A 1NNWA 2HYOA 3FGAC 3LL8A 4O24A 4MP0A 3K7WC 4ORAA 1S3NA 1IT6A 5INBA 1AUIA 1SU1A 2IE4C 4V0XA 3V4YA 3AV0A 3QFMA 2DFJA 2KKNA 3DSCA 2WDEA 1XM7A 3H69A 3H62B 5JPFA 4UT3A 5F3WA 4LTYA 1V73A 2IE3C 3KBPA 3PSNA 3H68A 4M0VA 1S3MA 2WDCA 4O43A 3P71C 1G5BA 2QJCA 3JYFA 5JJTA 3EGHA 4H2IA 4O5GA 4TUIA 4V0VA 1HO5A 4ZVZA 4FCXA 2P6BA 1II7A 3IB8A 3ICFA 3H63A 2BCDA 1UTEA 2NXFA 1KBPA 2Z06A 4OR9A 4KKZA 3CK2A 3ZU0A 4MOVA 1XZWA 4H2BA 4H2FA 3E7AA 4NZVA 3K7VC 2Z1AA 3C9FA 3QFNA 4G9JA 2QFRA 4WWLA 4FBWA 3TGHA 2QFPA 3RQZA 1OIEA 1S8EA 4IL1A 4UWQA 5C1VA 4O4KA 1UF3A 4FBQA 4TUGA 3THOB 3ZTVA 1U32A 4UT3B 4LU9A 1MF8A 2GJUA 3DW8C 4ORBA 4LACC 1OIDA 2BQ8X 4DSYA 3THNA 5J28A 1WARA 1S70A 4H1SA 4I5LC 1USHA 4Q7FA 2YVTA 3QG5C 1JK7A 1S3LA 2NPPC 2USHA 4JA7A 4F0ZA 5DNYA 1HP1A 3T1IA 3GVEA 2IAEC 3C5WC 2NYMC 3H64A 3PSOA 2XMOA 3IB7A 4YKEA 1TCOA 2JOGA 4ZX2A 1M63A 4JA9A 1T70A 4ORCA 1WAO1 3H67A 4MOYA 3H66A 5IOHA 5JPEA 2AHDA 2O8GA 3AUZA 4XPNA 4DHLA 4H2GA 2NYLC 1HPUA 3N5UA 4UT2A 3RL5A 4FBKA 3H61A 4V0WA 4H1YP 3HVQA 4B2OA 4IYPC 3IVDA 2O8AA 2WDFA 5HPEA 2WDDA 3QFKA 4J6OA 3H60A 3RL4A 3E7BA 1Z2XA 2HY1A 2Q8UA 3DSDA 4KBPA 2R17A 3EGGA 2BDXA 2A22A 1W24A 3QFOA 1FJMA 3RL3A 2Z72A 1S95A 3IVEA
chains in the Genus database with same CATH superfamily
2CV9A 2ZBMA 1T71A 1Z2WA 5B8IA 1OI8A 2HYPA 1QHWA 5EQVA 4HD0A 1QFCA 5GTUA 4I5NC 4DT2A 1NNWA 2HYOA 3FGAC 3LL8A 4O24A 4MP0A 3K7WC 4ORAA 1S3NA 1IT6A 5INBA 1AUIA 1SU1A 2IE4C 4V0XA 3V4YA 3AV0A 3QFMA 2DFJA 2KKNA 3DSCA 2WDEA 1XM7A 3H69A 3H62B 5JPFA 4UT3A 5F3WA 4LTYA 1V73A 2IE3C 3KBPA 3PSNA 3H68A 4M0VA 1S3MA 2WDCA 4O43A 3P71C 1G5BA 2QJCA 3JYFA 5JJTA 3EGHA 4H2IA 4O5GA 4TUIA 4V0VA 1HO5A 4ZVZA 4FCXA 2P6BA 1II7A 3IB8A 3ICFA 3H63A 2BCDA 1UTEA 2NXFA 1KBPA 2Z06A 4OR9A 3D03A 4KKZA 3CK2A 3ZU0A 3FLOA 4MOVA 1XZWA 2DXNA 4H2BA 4H2FA 3E7AA 4NZVA 3K7VC 2Z1AA 3C9FA 3QFNA 4G9JA 2QFRA 4WWLA 4FBWA 3TGHA 2QFPA 3RQZA 1OIEA 1S8EA 4IL1A 4UWQA 5C1VA 4O4KA 1UF3A 2ZO9B 4FBQA 4TUGA 3THOB 3ZTVA 1U32A 4UT3B 4LU9A 1MF8A 2GJUA 3DW8C 4ORBA 4LACC 1OIDA 2BQ8X 4DSYA 3THNA 5J28A 1WARA 1S70A 4H1SA 4I5LC 1USHA 4Q7FA 2YVTA 3QG5C 1JK7A 1S3LA 2NPPC 2USHA 4JA7A 4F0ZA 5DNYA 1HP1A 3T1IA 3GVEA 2IAEC 3C5WC 2NYMC 3H64A 3PSOA 2XMOA 2YEQA 3IB7A 1TCOA 4YKEA 2JOGA 4ZX2A 1M63A 4JA9A 1T70A 4ORCA 1WAO1 3H67A 4MOYA 3H66A 5IOHA 5JPEA 2AHDA 2O8GA 3AUZA 4XPNA 4DHLA 4H2GA 2NYLC 1HPUA 3N5UA 4UT2A 3RL5A 4FBKA 2ZOAA 3H61A 2DXLA 4V0WA 4H1YP 3HVQA 4B2OA 4IYPC 3IVDA 2O8AA 2WDFA 5HPEA 2WDDA 3QFKA 3E0JA 4J6OA 3H60A 3RL4A 3E7BA 1Z2XA 2HY1A 2Q8UA 3DSDA 4KBPA 2R17A 3EGGA 2BDXA 2A22A 1W24A 3QFOA 1FJMA 3RL3A 2Z72A 1S95A 3IVEA
chains in the Genus database with same CATH topology
2CV9A 2ZBMA 1T71A 1Z2WA 5B8IA 1OI8A 2HYPA 1QHWA 5EQVA 4HD0A 1QFCA 5GTUA 4I5NC 4DT2A 1NNWA 2HYOA 3FGAC 3LL8A 4O24A 4MP0A 3K7WC 4ORAA 1S3NA 1IT6A 5INBA 1AUIA 1SU1A 2IE4C 4V0XA 3V4YA 3AV0A 3QFMA 2DFJA 2KKNA 3DSCA 2WDEA 1XM7A 3H69A 3H62B 5JPFA 4UT3A 5F3WA 4LTYA 1V73A 2IE3C 3KBPA 3PSNA 3H68A 4M0VA 1S3MA 2WDCA 4O43A 3P71C 1G5BA 2QJCA 3JYFA 5JJTA 3EGHA 4H2IA 4O5GA 4TUIA 4V0VA 1HO5A 4ZVZA 4FCXA 2P6BA 1II7A 3IB8A 3ICFA 3H63A 2BCDA 1UTEA 2NXFA 1KBPA 2Z06A 4OR9A 3D03A 4KKZA 3CK2A 3ZU0A 3FLOA 4MOVA 1XZWA 2DXNA 4H2BA 4H2FA 3E7AA 4NZVA 3K7VC 2Z1AA 3C9FA 3QFNA 4G9JA 2QFRA 4WWLA 4FBWA 3TGHA 2QFPA 3RQZA 1OIEA 1S8EA 4IL1A 4UWQA 5C1VA 4O4KA 1UF3A 2ZO9B 4FBQA 4TUGA 3THOB 3ZTVA 1U32A 4UT3B 4LU9A 1MF8A 2GJUA 3DW8C 4ORBA 4LACC 1OIDA 2BQ8X 4DSYA 3THNA 5J28A 1WARA 1S70A 4H1SA 4I5LC 1USHA 4Q7FA 2YVTA 3QG5C 1JK7A 1S3LA 2NPPC 2USHA 4JA7A 4F0ZA 5DNYA 1HP1A 3T1IA 3GVEA 2IAEC 3C5WC 2NYMC 3H64A 3PSOA 2XMOA 2YEQA 3IB7A 1TCOA 4YKEA 2JOGA 4ZX2A 1M63A 4JA9A 1T70A 4ORCA 1WAO1 3H67A 4MOYA 3H66A 5IOHA 5JPEA 2AHDA 2O8GA 3AUZA 4XPNA 4DHLA 4H2GA 2NYLC 1HPUA 3N5UA 4UT2A 3RL5A 4FBKA 2ZOAA 3H61A 2DXLA 4V0WA 4H1YP 3HVQA 4B2OA 4IYPC 3IVDA 2O8AA 2WDFA 5HPEA 2WDDA 3QFKA 3E0JA 4J6OA 3H60A 3RL4A 3E7BA 1Z2XA 2HY1A 2Q8UA 3DSDA 4KBPA 2R17A 3EGGA 2BDXA 2A22A 1W24A 3QFOA 1FJMA 3RL3A 2Z72A 1S95A 3IVEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CV9 A;  2ZBM A;  1T71 A;  1Z2W A;  5B8I A;  1OI8 A;  2HYP A;  1QHW A;  5EQV A;  4HD0 A;  1QFC A;  5GTU A;  4I5N C;  4DT2 A;  1NNW A;  2HYO A;  3FGA C;  3LL8 A;  4O24 A;  4MP0 A;  3K7W C;  4ORA A;  1S3N A;  1IT6 A;  5INB A;  1AUI A;  1SU1 A;  2IE4 C;  4V0X A;  3V4Y A;  3AV0 A;  3QFM A;  2DFJ A;  2KKN A;  3DSC A;  2WDE A;  1XM7 A;  3H69 A;  3H62 B;  5JPF A;  4UT3 A;  5F3W A;  4LTY A;  1V73 A;  2IE3 C;  3KBP A;  3PSN A;  3H68 A;  4M0V A;  1S3M A;  2WDC A;  4O43 A;  3P71 C;  1G5B A;  2QJC A;  3JYF A;  5JJT A;  3EGH A;  4H2I A;  4O5G A;  4TUI A;  4V0V A;  1HO5 A;  4ZVZ A;  4FCX A;  2P6B A;  1II7 A;  3IB8 A;  3ICF A;  3H63 A;  2BCD A;  1UTE A;  2NXF A;  1KBP A;  2Z06 A;  4OR9 A;  4KKZ A;  3CK2 A;  3ZU0 A;  4MOV A;  1XZW A;  4H2B A;  4H2F A;  3E7A A;  4NZV A;  3K7V C;  2Z1A A;  3C9F A;  3QFN A;  4G9J A;  2QFR A;  4WWL A;  4FBW A;  3TGH A;  2QFP A;  3RQZ A;  1OIE A;  1S8E A;  4IL1 A;  4UWQ A;  5C1V A;  4O4K A;  1UF3 A;  4FBQ A;  4TUG A;  3THO B;  3ZTV A;  1U32 A;  4UT3 B;  4LU9 A;  1MF8 A;  2GJU A;  3DW8 C;  4ORB A;  4LAC C;  1OID A;  2BQ8 X;  4DSY A;  3THN A;  5J28 A;  1WAR A;  1S70 A;  4H1S A;  4I5L C;  1USH A;  4Q7F A;  2YVT A;  3QG5 C;  1JK7 A;  1S3L A;  2NPP C;  2USH A;  4JA7 A;  4F0Z A;  5DNY A;  1HP1 A;  3T1I A;  3GVE A;  2IAE C;  3C5W C;  2NYM C;  3H64 A;  3PSO A;  2XMO A;  3IB7 A;  4YKE A;  1TCO A;  2JOG A;  4ZX2 A;  1M63 A;  4JA9 A;  1T70 A;  4ORC A;  1WAO 1;  3H67 A;  4MOY A;  3H66 A;  5IOH A;  5JPE A;  2AHD A;  2O8G A;  3AUZ A;  4XPN A;  4DHL A;  4H2G A;  2NYL C;  1HPU A;  3N5U A;  4UT2 A;  3RL5 A;  4FBK A;  3H61 A;  4V0W A;  4H1Y P;  3HVQ A;  4B2O A;  4IYP C;  3IVD A;  2O8A A;  2WDF A;  5HPE A;  2WDD A;  3QFK A;  4J6O A;  3H60 A;  3RL4 A;  3E7B A;  1Z2X A;  2HY1 A;  2Q8U A;  3DSD A;  4KBP A;  2R17 A;  3EGG A;  2BDX A;  2A22 A;  1W24 A;  3QFO A;  1FJM A;  3RL3 A;  2Z72 A;  1S95 A;  3IVE A; 
#chains in the Genus database with same CATH topology
 2CV9 A;  2ZBM A;  1T71 A;  1Z2W A;  5B8I A;  1OI8 A;  2HYP A;  1QHW A;  5EQV A;  4HD0 A;  1QFC A;  5GTU A;  4I5N C;  4DT2 A;  1NNW A;  2HYO A;  3FGA C;  3LL8 A;  4O24 A;  4MP0 A;  3K7W C;  4ORA A;  1S3N A;  1IT6 A;  5INB A;  1AUI A;  1SU1 A;  2IE4 C;  4V0X A;  3V4Y A;  3AV0 A;  3QFM A;  2DFJ A;  2KKN A;  3DSC A;  2WDE A;  1XM7 A;  3H69 A;  3H62 B;  5JPF A;  4UT3 A;  5F3W A;  4LTY A;  1V73 A;  2IE3 C;  3KBP A;  3PSN A;  3H68 A;  4M0V A;  1S3M A;  2WDC A;  4O43 A;  3P71 C;  1G5B A;  2QJC A;  3JYF A;  5JJT A;  3EGH A;  4H2I A;  4O5G A;  4TUI A;  4V0V A;  1HO5 A;  4ZVZ A;  4FCX A;  2P6B A;  1II7 A;  3IB8 A;  3ICF A;  3H63 A;  2BCD A;  1UTE A;  2NXF A;  1KBP A;  2Z06 A;  4OR9 A;  3D03 A;  4KKZ A;  3CK2 A;  3ZU0 A;  3FLO A;  4MOV A;  1XZW A;  2DXN A;  4H2B A;  4H2F A;  3E7A A;  4NZV A;  3K7V C;  2Z1A A;  3C9F A;  3QFN A;  4G9J A;  2QFR A;  4WWL A;  4FBW A;  3TGH A;  2QFP A;  3RQZ A;  1OIE A;  1S8E A;  4IL1 A;  4UWQ A;  5C1V A;  4O4K A;  1UF3 A;  2ZO9 B;  4FBQ A;  4TUG A;  3THO B;  3ZTV A;  1U32 A;  4UT3 B;  4LU9 A;  1MF8 A;  2GJU A;  3DW8 C;  4ORB A;  4LAC C;  1OID A;  2BQ8 X;  4DSY A;  3THN A;  5J28 A;  1WAR A;  1S70 A;  4H1S A;  4I5L C;  1USH A;  4Q7F A;  2YVT A;  3QG5 C;  1JK7 A;  1S3L A;  2NPP C;  2USH A;  4JA7 A;  4F0Z A;  5DNY A;  1HP1 A;  3T1I A;  3GVE A;  2IAE C;  3C5W C;  2NYM C;  3H64 A;  3PSO A;  2XMO A;  2YEQ A;  3IB7 A;  1TCO A;  4YKE A;  2JOG A;  4ZX2 A;  1M63 A;  4JA9 A;  1T70 A;  4ORC A;  1WAO 1;  3H67 A;  4MOY A;  3H66 A;  5IOH A;  5JPE A;  2AHD A;  2O8G A;  3AUZ A;  4XPN A;  4DHL A;  4H2G A;  2NYL C;  1HPU A;  3N5U A;  4UT2 A;  3RL5 A;  4FBK A;  2ZOA A;  3H61 A;  2DXL A;  4V0W A;  4H1Y P;  3HVQ A;  4B2O A;  4IYP C;  3IVD A;  2O8A A;  2WDF A;  5HPE A;  2WDD A;  3QFK A;  3E0J A;  4J6O A;  3H60 A;  3RL4 A;  3E7B A;  1Z2X A;  2HY1 A;  2Q8U A;  3DSD A;  4KBP A;  2R17 A;  3EGG A;  2BDX A;  2A22 A;  1W24 A;  3QFO A;  1FJM A;  3RL3 A;  2Z72 A;  1S95 A;  3IVE A; 
#chains in the Genus database with same CATH homology
 2CV9 A;  2ZBM A;  1T71 A;  1Z2W A;  5B8I A;  1OI8 A;  2HYP A;  1QHW A;  5EQV A;  4HD0 A;  1QFC A;  5GTU A;  4I5N C;  4DT2 A;  1NNW A;  2HYO A;  3FGA C;  3LL8 A;  4O24 A;  4MP0 A;  3K7W C;  4ORA A;  1S3N A;  1IT6 A;  5INB A;  1AUI A;  1SU1 A;  2IE4 C;  4V0X A;  3V4Y A;  3AV0 A;  3QFM A;  2DFJ A;  2KKN A;  3DSC A;  2WDE A;  1XM7 A;  3H69 A;  3H62 B;  5JPF A;  4UT3 A;  5F3W A;  4LTY A;  1V73 A;  2IE3 C;  3KBP A;  3PSN A;  3H68 A;  4M0V A;  1S3M A;  2WDC A;  4O43 A;  3P71 C;  1G5B A;  2QJC A;  3JYF A;  5JJT A;  3EGH A;  4H2I A;  4O5G A;  4TUI A;  4V0V A;  1HO5 A;  4ZVZ A;  4FCX A;  2P6B A;  1II7 A;  3IB8 A;  3ICF A;  3H63 A;  2BCD A;  1UTE A;  2NXF A;  1KBP A;  2Z06 A;  4OR9 A;  3D03 A;  4KKZ A;  3CK2 A;  3ZU0 A;  3FLO A;  4MOV A;  1XZW A;  2DXN A;  4H2B A;  4H2F A;  3E7A A;  4NZV A;  3K7V C;  2Z1A A;  3C9F A;  3QFN A;  4G9J A;  2QFR A;  4WWL A;  4FBW A;  3TGH A;  2QFP A;  3RQZ A;  1OIE A;  1S8E A;  4IL1 A;  4UWQ A;  5C1V A;  4O4K A;  1UF3 A;  2ZO9 B;  4FBQ A;  4TUG A;  3THO B;  3ZTV A;  1U32 A;  4UT3 B;  4LU9 A;  1MF8 A;  2GJU A;  3DW8 C;  4ORB A;  4LAC C;  1OID A;  2BQ8 X;  4DSY A;  3THN A;  5J28 A;  1WAR A;  1S70 A;  4H1S A;  4I5L C;  1USH A;  4Q7F A;  2YVT A;  3QG5 C;  1JK7 A;  1S3L A;  2NPP C;  2USH A;  4JA7 A;  4F0Z A;  5DNY A;  1HP1 A;  3T1I A;  3GVE A;  2IAE C;  3C5W C;  2NYM C;  3H64 A;  3PSO A;  2XMO A;  2YEQ A;  3IB7 A;  1TCO A;  4YKE A;  2JOG A;  4ZX2 A;  1M63 A;  4JA9 A;  1T70 A;  4ORC A;  1WAO 1;  3H67 A;  4MOY A;  3H66 A;  5IOH A;  5JPE A;  2AHD A;  2O8G A;  3AUZ A;  4XPN A;  4DHL A;  4H2G A;  2NYL C;  1HPU A;  3N5U A;  4UT2 A;  3RL5 A;  4FBK A;  2ZOA A;  3H61 A;  2DXL A;  4V0W A;  4H1Y P;  3HVQ A;  4B2O A;  4IYP C;  3IVD A;  2O8A A;  2WDF A;  5HPE A;  2WDD A;  3QFK A;  3E0J A;  4J6O A;  3H60 A;  3RL4 A;  3E7B A;  1Z2X A;  2HY1 A;  2Q8U A;  3DSD A;  4KBP A;  2R17 A;  3EGG A;  2BDX A;  2A22 A;  1W24 A;  3QFO A;  1FJM A;  3RL3 A;  2Z72 A;  1S95 A;  3IVE A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...