2E2JL

Rna polymerase ii elongation complex in 5 mm mg+2 with gmpcpp
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords 5'-R(P*AP*UP*CP*GP*AP*GP*AP*GP*G)-3'
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2006-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2e2jL00
1SFOL 4BBRL 1Y1WL 3HOXL 5C4XL 1K83L 4C3HL 2E2IL 3RZOL 3M4OL 1I6HL 4A3BL 4A3FL 2NVQL 4A3LL 5IYBL 4C3IL 4Y7NL 2PMZP 5C3EL 4A93L 3GTLL 5IYDL 3S2DL 2B63L 3HOUL 3HOZL 4BXXL 3S16L 4A3ML 2R7ZL 3K7AL 3H3VM 3CQZL 2NVYL 4A3DL 4Y52L 2R93L 4BY1L 2NVXL 3S14L 3GTOL 1R9TL 3GTML 4AYBP 3S15L 1TWGL 2E2HL 1TWFL 3I4ML 4C2M1 4A3JL 3HOWL 4A3IL 2JA5L 2YU9L 3S1QL 2Y0SP 1TWHL 1I50L 4C3JL 2VUML 5M3ML 3M3YL 5M5WL 3PO3L 2R92L 3GTQL 2JA8L 1WCML 3HOYL 3GTJL 5IP9L 3S1ML 5IYCL 3GTKL 4A3EL 5C4JL 3S2HL 3GTPL 5M3FL 2NVTL 5M5XL 3HOVL 1Y1VL 5FJ8L 4A3GL 2WAQP 2WB1P 5M5YL 5IP7L 3HKZP 3S1RL 4X6AL 4BY7L 4BBSL 1I3QL 3FKIL 3I4NL 1TWAL 2JA6L 1TWCL 3GTGL 2JA7L 3S1NL 3RZDL 4A3KL 2E2JL 3H0GL 5C44L 5FLML 3S17L 4QIWP 3PO2L 4A3CL
chains in the Genus database with same CATH superfamily
5EINC 1S2ZA 2A6HD 4AI0A 3KYVA 2APOB 5GAHc 2E2IL 3RZOL 3SS2A 4GS7D 1R0GA 1DX8A 1LKPA 4YWMA 2XJSA 4Y7NL 3HJYB 3FDJA 3WWLA 5H1Sc 1P7PA 3HOUL 3HOZL 4BXXL 3PIP1 4TVMA 2M4VA 3CQZL 2NVYL 4A3DL 1BRFA 1S24A 3GTML 4AI3A 2V0EA 1YK5A 1TWFL 4A3JL 3HOWL 1WJVA 1IW7D 4A3IL 1PFUA 3RZTA 3J7Z1 2XJTA 1QYBA 1FHHA 2BE5D 2ERJA 5M3ML 5MF6A 5M5WL 2R92L 2JA8L 2C6BA 1WCML 3HOYL 5GAGc 1B2JA 2XJUA 4LHNA 4AR3A 5IP9L 4AI2A 5C4JL 4LHLA 1LTLA 2HR5A 4YWLA 1Y1VL 2WAQP 2A6ED 1OWBA 2B5ID 2PSMC 3I4NL 2H12A 3P8BA 3GTGL 2Z3QB 5DM61 4JADA 3PL5A 3LWRB 2E2JL 1F4LA 3S17L 2AQCA 1RYQA 3PO2L 1SFOL 4BBRL 4RXNA 1K83L 2M4YA 1R0HA 5IY0A 3NFPI 5JVH1 3A44A 1BQ9A 1NXEA 2PVEA 4A3FL 2NVQL 4XGHA 4POFA 2RDVA 5C3EL 4A93L 3IU3I 3GTLL 2EY4E 1R0IA 5IYDL 3S2DL 1RB9A 4JAEA 1JYBA 3S16L 1H7VA 3WWNB 3KYXA 4A3ML 2R7ZL 4V196 3K7AL 4Y52L 2R93L 3B08B 2AYJA 1E8JA 2NVXL 3S14L 1R9TL 1PZXA 2PVXA 3HJWB 2QL0A 1IU5A 1BQ8A 1ODHA 3S15L 1IROA 1TWGL 2JI1A 4C2M1 1BFYA 2ZIXA 3KYYA 4ZN1B 3KYUA 1YUZA 4U671 2Y0SP 1TWHL 3P2AA 1I50L 4C3JL 2VUML 8RXNA 2A68D 1S30A 4AHYA 6RXNA 4UY81 2O5JD 4AHZA 3PIO1 3RZ6A 3GTJL 1RDGA 2XJPA 3S1ML 5IYCL 1PFYA 3PKIA 2C6AA 2XJQA 3B0AB 2JI2A 5M3FL 5MGNA 2KKDA 3HOVL 2K2DA 2WB1P 4AHWA 5IP7L 3HKZP 3S1RL 4BBSL 1I3QL 2JA6L 4JAFA 2CR8A 1PFVA 1YV1A 3S1NL 1YUXA 5MFPA 4ME3A 2VL6A 1VZGA 1QQTA 1VCXA 5DM71 1Y1WL 5C4XL 1CAAA 2V0FA 4C3HL 4AR5A 2JI3A 1I6HL 1RDVA 4A3BL 3H97A 2CKCA 3H9CA 4C3IL 2PMZP 5MFZA 1ZRPA 2NYDA 3K35A 1SMWA 2PYAA 1YK4A 1SMUA 3H3VM 1PFWA 1B2OA 4AR6A 3GTOL 1LKMA 4POGA 1IU6A 1IRNA 2JA5L 5AI3A 3LNLA 2PPTA 1Z92B 2M6PA 1NXGA 3GTQL 1DVBA 3LWOB 3HAXC 3H99A 4JAGA 1B71A 3GTKL 2XJRA 2RFKB 3RYGA 2GMGA 5M5XL 2ERSA 2CKAA 3LWVB 5M5YL 1OWCA 4X6AL 3FKIL 1TWAL 1CADA 2JA7L 5FLML 2LCQA 2J9UB 4WFN1 5AN9H 3HOXL 4B8CD 3LPEB 4K9FA 3ZG6A 4AI1A 5AI2A 3M4OL 3QQCE 1RYTA 4ZN3B 2DSXA 4AHXA 4A3LL 5RXNA 5IYBL 5MLC3 3MPSA 4TPUA 1BE7A 3VPBE 2B63L 1T9PA 4AR4A 1SMMA 1T9QA 2V3BB 3PWFA 4XXBB 4BY1L 2L0ZA 3MQKB 1VZIA 3MSUA 1R0FA 4AYBP 3LWPB 2E2HL 3I4ML 3QVDA 2MS3A 3S1QL 2YU9L 2KN9A 1FHMA 5EIOC 1VZHA 3M3YL 1B13A 1R0JA 1RWDA 2A69D 2HVYC 3PO3L 1LKOA 3KYWA 3JR7A 5JVG1 4A3EL 1C09A 2M6OA 4E6YA 3S2HL 3PZAA 3GTPL 2NVTL 3J7Y1 3PKJA 5FJ8L 4A3GL 3LWQB 1QCVA 3H9BA 4BY7L 2AUSB 1T9OA 5K2ME 1TWCL 2XJVA 1NNQA 3RZDL 4A3KL 5GAEc 3H0GL 4G6BA 5C44L 7RXNA 4QIWP 5GADc 2Z3RB 4A3CL
chains in the Genus database with same CATH topology
1SFOL 4BBRL 1Y1WL 3HOXL 5C4XL 1K83L 4C3HL 2E2IL 3RZOL 3M4OL 1I6HL 4A3BL 4A3FL 2NVQL 4A3LL 5IYBL 4C3IL 4Y7NL 2PMZP 5C3EL 4A93L 3GTLL 5IYDL 3S2DL 2B63L 3HOUL 3HOZL 4BXXL 3S16L 4A3ML 2R7ZL 3K7AL 3H3VM 3CQZL 2NVYL 4A3DL 4Y52L 2R93L 4BY1L 2NVXL 3S14L 3GTOL 1R9TL 3GTML 4AYBP 3S15L 1TWGL 2E2HL 1TWFL 3I4ML 4C2M1 4A3JL 3HOWL 4A3IL 2JA5L 2YU9L 3S1QL 2Y0SP 1TWHL 1I50L 4C3JL 2VUML 5M3ML 3M3YL 5M5WL 3PO3L 2R92L 3GTQL 2JA8L 1WCML 3HOYL 3GTJL 5IP9L 3S1ML 5IYCL 3GTKL 4A3EL 5C4JL 3S2HL 3GTPL 5M3FL 2NVTL 5M5XL 3HOVL 1Y1VL 5FJ8L 4A3GL 2WAQP 2WB1P 5M5YL 5IP7L 3HKZP 3S1RL 4X6AL 4BY7L 4BBSL 1I3QL 3FKIL 3I4NL 1TWAL 2JA6L 1TWCL 3GTGL 2JA7L 3S1NL 3RZDL 4A3KL 2E2JL 3H0GL 5C44L 5FLML 3S17L 4QIWP 3PO2L 4A3CL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SFO L;  4BBR L;  1Y1W L;  3HOX L;  5C4X L;  1K83 L;  4C3H L;  2E2I L;  3RZO L;  3M4O L;  1I6H L;  4A3B L;  4A3F L;  2NVQ L;  4A3L L;  5IYB L;  4C3I L;  4Y7N L;  2PMZ P;  5C3E L;  4A93 L;  3GTL L;  5IYD L;  3S2D L;  2B63 L;  3HOU L;  3HOZ L;  4BXX L;  3S16 L;  4A3M L;  2R7Z L;  3K7A L;  3H3V M;  3CQZ L;  2NVY L;  4A3D L;  4Y52 L;  2R93 L;  4BY1 L;  2NVX L;  3S14 L;  3GTO L;  1R9T L;  3GTM L;  4AYB P;  3S15 L;  1TWG L;  2E2H L;  1TWF L;  3I4M L;  4C2M 1;  4A3J L;  3HOW L;  4A3I L;  2JA5 L;  2YU9 L;  3S1Q L;  2Y0S P;  1TWH L;  1I50 L;  4C3J L;  2VUM L;  5M3M L;  3M3Y L;  5M5W L;  3PO3 L;  2R92 L;  3GTQ L;  2JA8 L;  1WCM L;  3HOY L;  3GTJ L;  5IP9 L;  3S1M L;  5IYC L;  3GTK L;  4A3E L;  5C4J L;  3S2H L;  3GTP L;  5M3F L;  2NVT L;  5M5X L;  3HOV L;  1Y1V L;  5FJ8 L;  4A3G L;  2WAQ P;  2WB1 P;  5M5Y L;  5IP7 L;  3HKZ P;  3S1R L;  4X6A L;  4BY7 L;  4BBS L;  1I3Q L;  3FKI L;  3I4N L;  1TWA L;  2JA6 L;  1TWC L;  3GTG L;  2JA7 L;  3S1N L;  3RZD L;  4A3K L;  2E2J L;  3H0G L;  5C44 L;  5FLM L;  3S17 L;  4QIW P;  3PO2 L;  4A3C L; 
#chains in the Genus database with same CATH topology
 5EIN C;  1S2Z A;  2A6H D;  4AI0 A;  3KYV A;  2APO B;  5GAH c;  2E2I L;  3RZO L;  3SS2 A;  4GS7 D;  1R0G A;  1DX8 A;  1LKP A;  4YWM A;  2XJS A;  4Y7N L;  3HJY B;  3FDJ A;  3WWL A;  5H1S c;  1P7P A;  3HOU L;  3HOZ L;  4BXX L;  3PIP 1;  4TVM A;  2M4V A;  3CQZ L;  2NVY L;  4A3D L;  1BRF A;  1S24 A;  3GTM L;  4AI3 A;  2V0E A;  1YK5 A;  1TWF L;  4A3J L;  3HOW L;  1WJV A;  1IW7 D;  4A3I L;  1PFU A;  3RZT A;  3J7Z 1;  2XJT A;  1QYB A;  1FHH A;  2BE5 D;  2ERJ A;  5M3M L;  5MF6 A;  5M5W L;  2R92 L;  2JA8 L;  2C6B A;  1WCM L;  3HOY L;  5GAG c;  1B2J A;  2XJU A;  4LHN A;  4AR3 A;  5IP9 L;  4AI2 A;  5C4J L;  4LHL A;  1LTL A;  2HR5 A;  4YWL A;  1Y1V L;  2WAQ P;  2A6E D;  1OWB A;  2B5I D;  2PSM C;  3I4N L;  2H12 A;  3P8B A;  3GTG L;  2Z3Q B;  5DM6 1;  4JAD A;  3PL5 A;  3LWR B;  2E2J L;  1F4L A;  3S17 L;  2AQC A;  1RYQ A;  3PO2 L;  1SFO L;  4BBR L;  4RXN A;  1K83 L;  2M4Y A;  1R0H A;  5IY0 A;  3NFP I;  5JVH 1;  3A44 A;  1BQ9 A;  1NXE A;  2PVE A;  4A3F L;  2NVQ L;  4XGH A;  4POF A;  2RDV A;  5C3E L;  4A93 L;  3IU3 I;  3GTL L;  2EY4 E;  1R0I A;  5IYD L;  3S2D L;  1RB9 A;  4JAE A;  1JYB A;  3S16 L;  1H7V A;  3WWN B;  3KYX A;  4A3M L;  2R7Z L;  4V19 6;  3K7A L;  4Y52 L;  2R93 L;  3B08 B;  2AYJ A;  1E8J A;  2NVX L;  3S14 L;  1R9T L;  1PZX A;  2PVX A;  3HJW B;  2QL0 A;  1IU5 A;  1BQ8 A;  1ODH A;  3S15 L;  1IRO A;  1TWG L;  2JI1 A;  4C2M 1;  1BFY A;  2ZIX A;  3KYY A;  4ZN1 B;  3KYU A;  1YUZ A;  4U67 1;  2Y0S P;  1TWH L;  3P2A A;  1I50 L;  4C3J L;  2VUM L;  8RXN A;  2A68 D;  1S30 A;  4AHY A;  6RXN A;  4UY8 1;  2O5J D;  4AHZ A;  3PIO 1;  3RZ6 A;  3GTJ L;  1RDG A;  2XJP A;  3S1M L;  5IYC L;  1PFY A;  3PKI A;  2C6A A;  2XJQ A;  3B0A B;  2JI2 A;  5M3F L;  5MGN A;  2KKD A;  3HOV L;  2K2D A;  2WB1 P;  4AHW A;  5IP7 L;  3HKZ P;  3S1R L;  4BBS L;  1I3Q L;  2JA6 L;  4JAF A;  2CR8 A;  1PFV A;  1YV1 A;  3S1N L;  1YUX A;  5MFP A;  4ME3 A;  2VL6 A;  1VZG A;  1QQT A;  1VCX A;  5DM7 1;  1Y1W L;  5C4X L;  1CAA A;  2V0F A;  4C3H L;  4AR5 A;  2JI3 A;  1I6H L;  1RDV A;  4A3B L;  3H97 A;  2CKC A;  3H9C A;  4C3I L;  2PMZ P;  5MFZ A;  1ZRP A;  2NYD A;  3K35 A;  1SMW A;  2PYA A;  1YK4 A;  1SMU A;  3H3V M;  1PFW A;  1B2O A;  4AR6 A;  3GTO L;  1LKM A;  4POG A;  1IU6 A;  1IRN A;  2JA5 L;  5AI3 A;  3LNL A;  2PPT A;  1Z92 B;  2M6P A;  1NXG A;  3GTQ L;  1DVB A;  3LWO B;  3HAX C;  3H99 A;  4JAG A;  1B71 A;  3GTK L;  2XJR A;  2RFK B;  3RYG A;  2GMG A;  5M5X L;  2ERS A;  2CKA A;  3LWV B;  5M5Y L;  1OWC A;  4X6A L;  3FKI L;  1TWA L;  1CAD A;  2JA7 L;  5FLM L;  2LCQ A;  2J9U B;  4WFN 1;  5AN9 H;  3HOX L;  4B8C D;  3LPE B;  4K9F A;  3ZG6 A;  4AI1 A;  5AI2 A;  3M4O L;  3QQC E;  1RYT A;  4ZN3 B;  2DSX A;  4AHX A;  4A3L L;  5RXN A;  5IYB L;  5MLC 3;  3MPS A;  4TPU A;  1BE7 A;  3VPB E;  2B63 L;  1T9P A;  4AR4 A;  1SMM A;  1T9Q A;  2V3B B;  3PWF A;  4XXB B;  4BY1 L;  2L0Z A;  3MQK B;  1VZI A;  3MSU A;  1R0F A;  4AYB P;  3LWP B;  2E2H L;  3I4M L;  3QVD A;  2MS3 A;  3S1Q L;  2YU9 L;  2KN9 A;  1FHM A;  5EIO C;  1VZH A;  3M3Y L;  1B13 A;  1R0J A;  1RWD A;  2A69 D;  2HVY C;  3PO3 L;  1LKO A;  3KYW A;  3JR7 A;  5JVG 1;  4A3E L;  1C09 A;  2M6O A;  4E6Y A;  3S2H L;  3PZA A;  3GTP L;  2NVT L;  3J7Y 1;  3PKJ A;  5FJ8 L;  4A3G L;  3LWQ B;  1QCV A;  3H9B A;  4BY7 L;  2AUS B;  1T9O A;  5K2M E;  1TWC L;  2XJV A;  1NNQ A;  3RZD L;  4A3K L;  5GAE c;  3H0G L;  4G6B A;  5C44 L;  7RXN A;  4QIW P;  5GAD c;  2Z3R B;  4A3C L; 
#chains in the Genus database with same CATH homology
 1SFO L;  4BBR L;  1Y1W L;  3HOX L;  5C4X L;  1K83 L;  4C3H L;  2E2I L;  3RZO L;  3M4O L;  1I6H L;  4A3B L;  4A3F L;  2NVQ L;  4A3L L;  5IYB L;  4C3I L;  4Y7N L;  2PMZ P;  5C3E L;  4A93 L;  3GTL L;  5IYD L;  3S2D L;  2B63 L;  3HOU L;  3HOZ L;  4BXX L;  3S16 L;  4A3M L;  2R7Z L;  3K7A L;  3H3V M;  3CQZ L;  2NVY L;  4A3D L;  4Y52 L;  2R93 L;  4BY1 L;  2NVX L;  3S14 L;  3GTO L;  1R9T L;  3GTM L;  4AYB P;  3S15 L;  1TWG L;  2E2H L;  1TWF L;  3I4M L;  4C2M 1;  4A3J L;  3HOW L;  4A3I L;  2JA5 L;  2YU9 L;  3S1Q L;  2Y0S P;  1TWH L;  1I50 L;  4C3J L;  2VUM L;  5M3M L;  3M3Y L;  5M5W L;  3PO3 L;  2R92 L;  3GTQ L;  2JA8 L;  1WCM L;  3HOY L;  3GTJ L;  5IP9 L;  3S1M L;  5IYC L;  3GTK L;  4A3E L;  5C4J L;  3S2H L;  3GTP L;  5M3F L;  2NVT L;  5M5X L;  3HOV L;  1Y1V L;  5FJ8 L;  4A3G L;  2WAQ P;  2WB1 P;  5M5Y L;  5IP7 L;  3HKZ P;  3S1R L;  4X6A L;  4BY7 L;  4BBS L;  1I3Q L;  3FKI L;  3I4N L;  1TWA L;  2JA6 L;  1TWC L;  3GTG L;  2JA7 L;  3S1N L;  3RZD L;  4A3K L;  2E2J L;  3H0G L;  5C44 L;  5FLM L;  3S17 L;  4QIW P;  3PO2 L;  4A3C L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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