2HYOA

Crystal structure of rv0805 n97a mutant
Total Genus 70
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
256
structure length
227
Chain Sequence
PRPDYVLLHISDTHLIDADDRLGELLEQLNQSGLRPDAIVFTGDLADKGEPAAYRKLRGLVEPFAAQLGAELVWVMGAHDDRAELRKFLLDEAPSMAPLDRVCMIDGLRIIVLDTSVPGHHHGEIRASQLGWLAEELATPAPDGTILALHHPPIPSVLDMAVTVELRDQAALGRVLRGTDVRAILAGHLHYSTNATFVGIPVSVASATCGCNLVHVYPDTVVHSVIP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural and Biochemical Analysis of the Rv0805 Cyclic Nucleotide Phosphodiesterase from Mycobacterium tuberculosis.
pubmed doi rcsb
molecule keywords Rv0805N97A
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
total genus 70
structure length 227
sequence length 256
ec nomenclature ec 3.1.4.53: 3',5'-cyclic-AMP phosphodiesterase.
pdb deposition date 2006-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2hyoA00
4JA9A 2KKNA 2BDXA 4ZVZA 2NPPC 1U32A 2Z1AA 1WAO1 3DSDA 1TCOA 5JJTA 3CK2A 3HVQA 1SU1A 4DSYA 3H60A 4V0XA 4V0WA 2NYMC 1UF3A 3KBPA 1IT6A 1M63A 1G5BA 1V73A 4FBWA 1W24A 4H1YP 5JPFA 2GJUA 2WDFA 2IE4C 3K7VC 4MP0A 4KKZA 2HY1A 2QJCA 4I5LC 4J6OA 1Z2XA 4TUIA 5INBA 1S3LA 2A22A 5C1VA 2R17A 3K7WC 2WDCA 3ICFA 4H1SA 4FBQA 3IVEA 5JPEA 1S3NA 4TUGA 3RQZA 1OIEA 1S8EA 2QFPA 4KBPA 4V0VA 2IE3C 5HPEA 1OIDA 3IB7A 1T70A 1KBPA 3IB8A 4I5NC 5B8IA 1S95A 4ZX2A 3EGGA 4ORBA 2IAEC 4FBKA 1OI8A 3EGHA 3LL8A 3GVEA 3QFOA 4XPNA 1II7A 1MF8A 4ORAA 1HO5A 2DFJA 2YVTA 2JOGA 2HYOA 1QHWA 2HYPA 4F0ZA 4Q7FA 4UWQA 2BCDA 4H2GA 3C9FA 5DNYA 3TGHA 2USHA 3P71C 4IYPC 3AV0A 4OR9A 5F3WA 4LTYA 2NXFA 3ZTVA 4WWLA 1WARA 1T71A 3T1IA 3H62B 1FJMA 3N5UA 2QFRA 4UT2A 3QG5C 3IVDA 2NYLC 3THOB 2ZBMA 1HPUA 4UT3A 1NNWA 1XZWA 1XM7A 2O8AA 4DHLA 1AUIA 2Z72A 3E7AA 3QFNA 4HD0A 1UTEA 3RL3A 4NZVA 3PSOA 4H2BA 4LU9A 3RL5A 3H61A 3QFMA 4IL1A 4JA7A 4MOYA 4G9JA 4O43A 4UT3B 5IOHA 5J28A 4M0VA 3THNA 4O24A 3AUZA 2CV9A 2O8GA 1S3MA 2Z06A 3DSCA 4DT2A 1Z2WA 3H67A 3QFKA 5GTUA 3FGAC 3PSNA 3C5WC 3H69A 4O4KA 2WDDA 3V4YA 2Q8UA 2WDEA 2BQ8X 3H64A 4H2IA 3H63A 2XMOA 3H66A 1S70A 1JK7A 1QFCA 3DW8C 4ORCA 4YKEA 5EQVA 3E7BA 3RL4A 4O5GA 4B2OA 2P6BA 3H68A 1HP1A 4H2FA 4LACC 4FCXA 4MOVA 3ZU0A 1USHA 3JYFA 2AHDA
chains in the Genus database with same CATH superfamily
4JA9A 2KKNA 2BDXA 4ZVZA 2NPPC 1U32A 2Z1AA 1WAO1 3DSDA 1TCOA 5JJTA 3CK2A 2DXNA 3HVQA 1SU1A 4DSYA 3H60A 4V0XA 4V0WA 2NYMC 1UF3A 3KBPA 1IT6A 1M63A 1G5BA 1V73A 4FBWA 1W24A 4H1YP 5JPFA 2GJUA 2WDFA 2IE4C 3K7VC 4MP0A 4KKZA 2HY1A 2QJCA 4I5LC 4J6OA 1Z2XA 4TUIA 5INBA 1S3LA 2A22A 5C1VA 2R17A 3K7WC 2WDCA 3ICFA 4H1SA 4FBQA 3IVEA 5JPEA 1S3NA 4TUGA 3RQZA 1OIEA 1S8EA 2QFPA 4KBPA 4V0VA 2IE3C 5HPEA 1OIDA 3IB7A 1T70A 1KBPA 3IB8A 4I5NC 5B8IA 1S95A 4ZX2A 3EGGA 4ORBA 2IAEC 4FBKA 1OI8A 3EGHA 3LL8A 3GVEA 3QFOA 4XPNA 1II7A 1MF8A 4ORAA 1HO5A 2DFJA 2YVTA 2JOGA 2HYOA 1QHWA 2HYPA 4F0ZA 4Q7FA 4UWQA 2BCDA 4H2GA 3C9FA 5DNYA 3TGHA 2USHA 3P71C 4IYPC 3AV0A 4OR9A 5F3WA 4LTYA 2NXFA 3ZTVA 4WWLA 1WARA 1T71A 3T1IA 3H62B 1FJMA 3N5UA 2QFRA 4UT2A 3QG5C 3IVDA 2NYLC 3THOB 2ZBMA 1HPUA 4UT3A 1NNWA 1XZWA 1XM7A 2O8AA 4DHLA 1AUIA 2Z72A 3E7AA 3QFNA 4HD0A 1UTEA 3RL3A 4NZVA 3PSOA 4H2BA 4LU9A 3RL5A 3H61A 3QFMA 4IL1A 4JA7A 4MOYA 4G9JA 4O43A 2ZO9B 4UT3B 5IOHA 5J28A 4M0VA 3THNA 3D03A 4O24A 3AUZA 3E0JA 2CV9A 2O8GA 1S3MA 2Z06A 3DSCA 4DT2A 1Z2WA 3H67A 3QFKA 5GTUA 3FGAC 3PSNA 3C5WC 3H69A 4O4KA 2WDDA 3V4YA 2Q8UA 2WDEA 2BQ8X 3H64A 4H2IA 3H63A 2XMOA 3H66A 1S70A 1JK7A 1QFCA 3DW8C 4ORCA 4YKEA 5EQVA 3E7BA 3RL4A 4O5GA 4B2OA 2P6BA 2ZOAA 1HP1A 2DXLA 3H68A 4H2FA 4LACC 2YEQA 3FLOA 4FCXA 4MOVA 3ZU0A 1USHA 3JYFA 2AHDA
chains in the Genus database with same CATH topology
4JA9A 2KKNA 2BDXA 4ZVZA 2NPPC 1U32A 2Z1AA 1WAO1 3DSDA 1TCOA 5JJTA 3CK2A 2DXNA 3HVQA 1SU1A 4DSYA 3H60A 4V0XA 4V0WA 2NYMC 1UF3A 3KBPA 1IT6A 1M63A 1G5BA 1V73A 4FBWA 1W24A 4H1YP 5JPFA 2GJUA 2WDFA 2IE4C 3K7VC 4MP0A 4KKZA 2HY1A 2QJCA 4I5LC 4J6OA 1Z2XA 4TUIA 5INBA 1S3LA 2A22A 5C1VA 2R17A 3K7WC 2WDCA 3ICFA 4H1SA 4FBQA 3IVEA 5JPEA 1S3NA 4TUGA 3RQZA 1OIEA 1S8EA 2QFPA 4KBPA 4V0VA 2IE3C 5HPEA 1OIDA 3IB7A 1T70A 1KBPA 3IB8A 4I5NC 5B8IA 1S95A 4ZX2A 3EGGA 4ORBA 2IAEC 4FBKA 1OI8A 3EGHA 3LL8A 3GVEA 3QFOA 4XPNA 1II7A 1MF8A 4ORAA 1HO5A 2DFJA 2YVTA 2JOGA 2HYOA 1QHWA 2HYPA 4F0ZA 4Q7FA 4UWQA 2BCDA 4H2GA 3C9FA 5DNYA 3TGHA 2USHA 3P71C 4IYPC 3AV0A 4OR9A 5F3WA 4LTYA 2NXFA 3ZTVA 4WWLA 1WARA 1T71A 3T1IA 3H62B 1FJMA 3N5UA 2QFRA 4UT2A 3QG5C 3IVDA 2NYLC 3THOB 2ZBMA 1HPUA 4UT3A 1NNWA 1XZWA 1XM7A 2O8AA 4DHLA 1AUIA 2Z72A 3E7AA 3QFNA 4HD0A 1UTEA 3RL3A 4NZVA 3PSOA 4H2BA 4LU9A 3RL5A 3H61A 3QFMA 4IL1A 4JA7A 4MOYA 4G9JA 4O43A 2ZO9B 4UT3B 5IOHA 5J28A 4M0VA 3THNA 3D03A 4O24A 3AUZA 3E0JA 2CV9A 2O8GA 1S3MA 2Z06A 3DSCA 4DT2A 1Z2WA 3H67A 3QFKA 5GTUA 3FGAC 3PSNA 3C5WC 3H69A 4O4KA 2WDDA 3V4YA 2Q8UA 2WDEA 2BQ8X 3H64A 4H2IA 3H63A 2XMOA 3H66A 1S70A 1JK7A 1QFCA 3DW8C 4ORCA 4YKEA 5EQVA 3E7BA 3RL4A 4O5GA 4B2OA 2P6BA 2ZOAA 1HP1A 2DXLA 3H68A 4H2FA 4LACC 2YEQA 3FLOA 4FCXA 4MOVA 3ZU0A 1USHA 3JYFA 2AHDA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4JA9 A;  2KKN A;  2BDX A;  4ZVZ A;  2NPP C;  1U32 A;  2Z1A A;  1WAO 1;  3DSD A;  1TCO A;  5JJT A;  3CK2 A;  3HVQ A;  1SU1 A;  4DSY A;  3H60 A;  4V0X A;  4V0W A;  2NYM C;  1UF3 A;  3KBP A;  1IT6 A;  1M63 A;  1G5B A;  1V73 A;  4FBW A;  1W24 A;  4H1Y P;  5JPF A;  2GJU A;  2WDF A;  2IE4 C;  3K7V C;  4MP0 A;  4KKZ A;  2HY1 A;  2QJC A;  4I5L C;  4J6O A;  1Z2X A;  4TUI A;  5INB A;  1S3L A;  2A22 A;  5C1V A;  2R17 A;  3K7W C;  2WDC A;  3ICF A;  4H1S A;  4FBQ A;  3IVE A;  5JPE A;  1S3N A;  4TUG A;  3RQZ A;  1OIE A;  1S8E A;  2QFP A;  4KBP A;  4V0V A;  2IE3 C;  5HPE A;  1OID A;  3IB7 A;  1T70 A;  1KBP A;  3IB8 A;  4I5N C;  5B8I A;  1S95 A;  4ZX2 A;  3EGG A;  4ORB A;  2IAE C;  4FBK A;  1OI8 A;  3EGH A;  3LL8 A;  3GVE A;  3QFO A;  4XPN A;  1II7 A;  1MF8 A;  4ORA A;  1HO5 A;  2DFJ A;  2YVT A;  2JOG A;  2HYO A;  1QHW A;  2HYP A;  4F0Z A;  4Q7F A;  4UWQ A;  2BCD A;  4H2G A;  3C9F A;  5DNY A;  3TGH A;  2USH A;  3P71 C;  4IYP C;  3AV0 A;  4OR9 A;  5F3W A;  4LTY A;  2NXF A;  3ZTV A;  4WWL A;  1WAR A;  1T71 A;  3T1I A;  3H62 B;  1FJM A;  3N5U A;  2QFR A;  4UT2 A;  3QG5 C;  3IVD A;  2NYL C;  3THO B;  2ZBM A;  1HPU A;  4UT3 A;  1NNW A;  1XZW A;  1XM7 A;  2O8A A;  4DHL A;  1AUI A;  2Z72 A;  3E7A A;  3QFN A;  4HD0 A;  1UTE A;  3RL3 A;  4NZV A;  3PSO A;  4H2B A;  4LU9 A;  3RL5 A;  3H61 A;  3QFM A;  4IL1 A;  4JA7 A;  4MOY A;  4G9J A;  4O43 A;  4UT3 B;  5IOH A;  5J28 A;  4M0V A;  3THN A;  4O24 A;  3AUZ A;  2CV9 A;  2O8G A;  1S3M A;  2Z06 A;  3DSC A;  4DT2 A;  1Z2W A;  3H67 A;  3QFK A;  5GTU A;  3FGA C;  3PSN A;  3C5W C;  3H69 A;  4O4K A;  2WDD A;  3V4Y A;  2Q8U A;  2WDE A;  2BQ8 X;  3H64 A;  4H2I A;  3H63 A;  2XMO A;  3H66 A;  1S70 A;  1JK7 A;  1QFC A;  3DW8 C;  4ORC A;  4YKE A;  5EQV A;  3E7B A;  3RL4 A;  4O5G A;  4B2O A;  2P6B A;  3H68 A;  1HP1 A;  4H2F A;  4LAC C;  4FCX A;  4MOV A;  3ZU0 A;  1USH A;  3JYF A;  2AHD A; 
#chains in the Genus database with same CATH topology
 4JA9 A;  2KKN A;  2BDX A;  4ZVZ A;  2NPP C;  1U32 A;  2Z1A A;  1WAO 1;  3DSD A;  1TCO A;  5JJT A;  3CK2 A;  2DXN A;  3HVQ A;  1SU1 A;  4DSY A;  3H60 A;  4V0X A;  4V0W A;  2NYM C;  1UF3 A;  3KBP A;  1IT6 A;  1M63 A;  1G5B A;  1V73 A;  4FBW A;  1W24 A;  4H1Y P;  5JPF A;  2GJU A;  2WDF A;  2IE4 C;  3K7V C;  4MP0 A;  4KKZ A;  2HY1 A;  2QJC A;  4I5L C;  4J6O A;  1Z2X A;  4TUI A;  5INB A;  1S3L A;  2A22 A;  5C1V A;  2R17 A;  3K7W C;  2WDC A;  3ICF A;  4H1S A;  4FBQ A;  3IVE A;  5JPE A;  1S3N A;  4TUG A;  3RQZ A;  1OIE A;  1S8E A;  2QFP A;  4KBP A;  4V0V A;  2IE3 C;  5HPE A;  1OID A;  3IB7 A;  1T70 A;  1KBP A;  3IB8 A;  4I5N C;  5B8I A;  1S95 A;  4ZX2 A;  3EGG A;  4ORB A;  2IAE C;  4FBK A;  1OI8 A;  3EGH A;  3LL8 A;  3GVE A;  3QFO A;  4XPN A;  1II7 A;  1MF8 A;  4ORA A;  1HO5 A;  2DFJ A;  2YVT A;  2JOG A;  2HYO A;  1QHW A;  2HYP A;  4F0Z A;  4Q7F A;  4UWQ A;  2BCD A;  4H2G A;  3C9F A;  5DNY A;  3TGH A;  2USH A;  3P71 C;  4IYP C;  3AV0 A;  4OR9 A;  5F3W A;  4LTY A;  2NXF A;  3ZTV A;  4WWL A;  1WAR A;  1T71 A;  3T1I A;  3H62 B;  1FJM A;  3N5U A;  2QFR A;  4UT2 A;  3QG5 C;  3IVD A;  2NYL C;  3THO B;  2ZBM A;  1HPU A;  4UT3 A;  1NNW A;  1XZW A;  1XM7 A;  2O8A A;  4DHL A;  1AUI A;  2Z72 A;  3E7A A;  3QFN A;  4HD0 A;  1UTE A;  3RL3 A;  4NZV A;  3PSO A;  4H2B A;  4LU9 A;  3RL5 A;  3H61 A;  3QFM A;  4IL1 A;  4JA7 A;  4MOY A;  4G9J A;  4O43 A;  2ZO9 B;  4UT3 B;  5IOH A;  5J28 A;  4M0V A;  3THN A;  3D03 A;  4O24 A;  3AUZ A;  3E0J A;  2CV9 A;  2O8G A;  1S3M A;  2Z06 A;  3DSC A;  4DT2 A;  1Z2W A;  3H67 A;  3QFK A;  5GTU A;  3FGA C;  3PSN A;  3C5W C;  3H69 A;  4O4K A;  2WDD A;  3V4Y A;  2Q8U A;  2WDE A;  2BQ8 X;  3H64 A;  4H2I A;  3H63 A;  2XMO A;  3H66 A;  1S70 A;  1JK7 A;  1QFC A;  3DW8 C;  4ORC A;  4YKE A;  5EQV A;  3E7B A;  3RL4 A;  4O5G A;  4B2O A;  2P6B A;  2ZOA A;  1HP1 A;  2DXL A;  3H68 A;  4H2F A;  4LAC C;  2YEQ A;  3FLO A;  4FCX A;  4MOV A;  3ZU0 A;  1USH A;  3JYF A;  2AHD A; 
#chains in the Genus database with same CATH homology
 4JA9 A;  2KKN A;  2BDX A;  4ZVZ A;  2NPP C;  1U32 A;  2Z1A A;  1WAO 1;  3DSD A;  1TCO A;  5JJT A;  3CK2 A;  2DXN A;  3HVQ A;  1SU1 A;  4DSY A;  3H60 A;  4V0X A;  4V0W A;  2NYM C;  1UF3 A;  3KBP A;  1IT6 A;  1M63 A;  1G5B A;  1V73 A;  4FBW A;  1W24 A;  4H1Y P;  5JPF A;  2GJU A;  2WDF A;  2IE4 C;  3K7V C;  4MP0 A;  4KKZ A;  2HY1 A;  2QJC A;  4I5L C;  4J6O A;  1Z2X A;  4TUI A;  5INB A;  1S3L A;  2A22 A;  5C1V A;  2R17 A;  3K7W C;  2WDC A;  3ICF A;  4H1S A;  4FBQ A;  3IVE A;  5JPE A;  1S3N A;  4TUG A;  3RQZ A;  1OIE A;  1S8E A;  2QFP A;  4KBP A;  4V0V A;  2IE3 C;  5HPE A;  1OID A;  3IB7 A;  1T70 A;  1KBP A;  3IB8 A;  4I5N C;  5B8I A;  1S95 A;  4ZX2 A;  3EGG A;  4ORB A;  2IAE C;  4FBK A;  1OI8 A;  3EGH A;  3LL8 A;  3GVE A;  3QFO A;  4XPN A;  1II7 A;  1MF8 A;  4ORA A;  1HO5 A;  2DFJ A;  2YVT A;  2JOG A;  2HYO A;  1QHW A;  2HYP A;  4F0Z A;  4Q7F A;  4UWQ A;  2BCD A;  4H2G A;  3C9F A;  5DNY A;  3TGH A;  2USH A;  3P71 C;  4IYP C;  3AV0 A;  4OR9 A;  5F3W A;  4LTY A;  2NXF A;  3ZTV A;  4WWL A;  1WAR A;  1T71 A;  3T1I A;  3H62 B;  1FJM A;  3N5U A;  2QFR A;  4UT2 A;  3QG5 C;  3IVD A;  2NYL C;  3THO B;  2ZBM A;  1HPU A;  4UT3 A;  1NNW A;  1XZW A;  1XM7 A;  2O8A A;  4DHL A;  1AUI A;  2Z72 A;  3E7A A;  3QFN A;  4HD0 A;  1UTE A;  3RL3 A;  4NZV A;  3PSO A;  4H2B A;  4LU9 A;  3RL5 A;  3H61 A;  3QFM A;  4IL1 A;  4JA7 A;  4MOY A;  4G9J A;  4O43 A;  2ZO9 B;  4UT3 B;  5IOH A;  5J28 A;  4M0V A;  3THN A;  3D03 A;  4O24 A;  3AUZ A;  3E0J A;  2CV9 A;  2O8G A;  1S3M A;  2Z06 A;  3DSC A;  4DT2 A;  1Z2W A;  3H67 A;  3QFK A;  5GTU A;  3FGA C;  3PSN A;  3C5W C;  3H69 A;  4O4K A;  2WDD A;  3V4Y A;  2Q8U A;  2WDE A;  2BQ8 X;  3H64 A;  4H2I A;  3H63 A;  2XMO A;  3H66 A;  1S70 A;  1JK7 A;  1QFC A;  3DW8 C;  4ORC A;  4YKE A;  5EQV A;  3E7B A;  3RL4 A;  4O5G A;  4B2O A;  2P6B A;  2ZOA A;  1HP1 A;  2DXL A;  3H68 A;  4H2F A;  4LAC C;  2YEQ A;  3FLO A;  4FCX A;  4MOV A;  3ZU0 A;  1USH A;  3JYF A;  2AHD A;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite