2NVXL

Rna polymerase ii elongation complex in 5 mm mg+2 with 2'-dutp
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2006-11-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2nvxL00
5IYCL 5IP7L 3M3YL 3PO2L 5M3FL 2NVTL 4A3BL 4QIWP 2PMZP 2WB1P 1TWHL 4A3LL 1Y1VL 1I6HL 3S1QL 1TWCL 4BBSL 3GTML 1I3QL 3RZOL 4Y52L 4BY1L 3GTKL 4A3CL 3HKZP 2E2HL 2NVQL 4A3GL 2NVXL 2JA8L 4A3EL 3S17L 4BBRL 1R9TL 4BY7L 3S15L 3HOWL 2YU9L 3HOXL 3K7AL 3CQZL 2B63L 5C4JL 2Y0SP 3GTOL 3H0GL 4C3HL 3GTJL 2E2JL 3GTGL 5M3ML 2WAQP 3S1NL 3FKIL 2JA7L 4A3ML 5M5XL 5C4XL 1TWAL 4A3KL 4C3IL 4C3JL 3M4OL 3S1ML 1TWGL 3S2DL 2R92L 3H3VM 4C2M1 3HOZL 1TWFL 5C44L 2JA6L 3HOUL 4A3IL 5FLML 3HOYL 4X6AL 3GTPL 4A3FL 2E2IL 3PO3L 3I4ML 3I4NL 1SFOL 2JA5L 3HOVL 5M5YL 3RZDL 5IYDL 2R7ZL 2R93L 3GTQL 5IYBL 5M5WL 4A3JL 3S16L 1K83L 3S14L 4BXXL 4A3DL 1I50L 4AYBP 3GTLL 2NVYL 1Y1WL 5IP9L 3S2HL 4A93L 3S1RL 4Y7NL 5FJ8L 1WCML 5C3EL 2VUML
chains in the Genus database with same CATH superfamily
1LTLA 1C09A 4AR4A 3PO2L 2NVTL 3PIP1 2WB1P 3RZ6A 3LWOB 1I3QL 3LPEB 1IU6A 4Y52L 4XGHA 4POGA 5MFZA 3H9BA 3HKZP 4JAFA 4TPUA 5JVH1 4ME3A 4A3EL 2V0EA 3HOWL 2YU9L 3H97A 4YWLA 1ZRPA 3GTGL 3J7Y1 2WAQP 5DM61 5GAEc 4UY81 3NFPI 3KYUA 1SMUA 2NYDA 1TWAL 5MGNA 4A3KL 1VCXA 8RXNA 5RXNA 2MS3A 2A6HD 4XXBB 3S2DL 1JYBA 3LWPB 2L0ZA 2PVXA 4AR5A 2JA6L 4A3IL 1IU5A 4TVMA 4JAGA 3HOYL 4X6AL 1F4LA 4AR3A 1VZGA 4A3FL 2E2IL 3PO3L 2HVYC 1IROA 2PVEA 1SFOL 2B5ID 1VZHA 1T9PA 2PSMC 1R0JA 3RZTA 3GTQL 2KKDA 3H9CA 2XJPA 3LNLA 3P2AA 3VPBE 4A3DL 3GTLL 4AYBP 1IW7D 4AI0A 1B13A 4JAEA 4K9FA 4Y7NL 3LWVB 1T9OA 1WCML 3MSUA 2VUML 1BE7A 5IYCL 3J7Z1 5M3FL 1B71A 7RXNA 3B08B 4ZN1B 1BFYA 4A3LL 1SMWA 1Y1VL 1PFUA 2XJSA 4BBSL 3RZOL 4BY1L 1R0HA 1PFWA 1RDGA 1B2OA 3ZG6A 3HAXC 4A3GL 1RYTA 2KN9A 2NVXL 3JR7A 3KYWA 4AHYA 3S15L 1WJVA 3KYYA 3HOXL 5C4JL 2Y0SP 3PZAA 2E2JL 1RB9A 3H99A 3K35A 2PPTA 2EY4E 3S1NL 4AR6A 1YV1A 3KYVA 3B0AB 2JA7L 5GADc 2CKCA 1BQ9A 3IU3I 3MPSA 3M4OL 3S1ML 1FHMA 1TWGL 2LCQA 1CAAA 2JI3A 1NXGA 3RYGA 2R92L 4E6YA 2M4YA 4G6BA 4AHXA 3HOZL 1TWFL 5EIOC 3WWLA 3PIO1 2J9UB 1R0GA 3LWRB 1YUZA 1LKOA 2VL6A 1CADA 2C6BA 2BE5D 4U671 3S16L 3S14L 1T9QA 1BRFA 2NVYL 1Y1WL 1IRNA 5IP9L 1LKPA 5C3EL 3MQKB 1YUXA 1LKMA 5IP7L 2V0FA 4A3BL 1B2JA 3P8BA 4QIWP 2XJRA 5AI3A 4AHWA 3S1QL 1TWCL 2A68D 1YK5A 1SMMA 3QQCE 2NVQL 1QCVA 1Z92B 1OWCA 2JA8L 4AI3A 4WFN1 4BBRL 3HJWB 2AYJA 4B8CD 1R9TL 1DVBA 3KYXA 2M6OA 3CQZL 3GTJL 4V196 5AI2A 5AN9H 4AHZA 2XJVA 4LHLA 3FKIL 5C4XL 1QYBA 2DSXA 1QQTA 4GS7D 4C3IL 5DM71 2M6PA 2CKAA 2ERJA 5IY0A 5C44L 2JI2A 2AUSB 1PFVA 1RWDA 3GTPL 1RDVA 3PWFA 1DX8A 2ERSA 3SS2A 2JA5L 5M5YL 5JVG1 3RZDL 5IYDL 2R7ZL 4LHNA 5IYBL 2A6ED 4A3JL 1K83L 6RXNA 4ZN3B 1I50L 1R0FA 4A93L 2APOB 5FJ8L 5GAGc 3A44A 2H12A 2V3BB 1RYQA 3M3YL 2K2DA 2PMZP 1TWHL 2PYAA 1OWBA 4JADA 1I6HL 3LWQB 2GMGA 3GTML 3GTKL 1BQ8A 4A3CL 1VZIA 2XJUA 1PFYA 2AQCA 2E2HL 2RDVA 1NNQA 2QL0A 2M4VA 2C6AA 4AI1A 5GAHc 3S17L 1NXEA 2ZIXA 4AI2A 4BY7L 2RFKB 3K7AL 2B63L 2CR8A 3GTOL 3H0GL 4C3HL 2Z3QB 5M3ML 1S30A 3PL5A 4A3ML 1R0IA 5M5XL 3PKJA 4C3JL 3QVDA 3H3VM 4C2M1 3HJYB 4RXNA 1FHHA 1PZXA 2Z3RB 1S24A 1H7VA 3HOUL 5MLC3 5FLML 1P7PA 3FDJA 2XJQA 5K2ME 1YK4A 2HR5A 5EINC 3I4ML 3WWNB 3I4NL 2A69D 3PKIA 3HOVL 4POFA 1E8JA 2R93L 2XJTA 5MF6A 5M5WL 5MFPA 4BXXL 5H1Sc 3S2HL 1S2ZA 3S1RL 2O5JD 2JI1A 4YWMA 1ODHA
chains in the Genus database with same CATH topology
5IYCL 5IP7L 3M3YL 3PO2L 5M3FL 2NVTL 4A3BL 4QIWP 2PMZP 2WB1P 1TWHL 4A3LL 1Y1VL 1I6HL 3S1QL 1TWCL 4BBSL 3GTML 1I3QL 3RZOL 4Y52L 4BY1L 3GTKL 4A3CL 3HKZP 2E2HL 2NVQL 4A3GL 2NVXL 2JA8L 4A3EL 3S17L 4BBRL 1R9TL 4BY7L 3S15L 3HOWL 2YU9L 3HOXL 3K7AL 3CQZL 2B63L 5C4JL 2Y0SP 3GTOL 3H0GL 4C3HL 3GTJL 2E2JL 3GTGL 5M3ML 2WAQP 3S1NL 3FKIL 2JA7L 4A3ML 5M5XL 5C4XL 1TWAL 4A3KL 4C3IL 4C3JL 3M4OL 3S1ML 1TWGL 3S2DL 2R92L 3H3VM 4C2M1 3HOZL 1TWFL 5C44L 2JA6L 3HOUL 4A3IL 5FLML 3HOYL 4X6AL 3GTPL 4A3FL 2E2IL 3PO3L 3I4ML 3I4NL 1SFOL 2JA5L 3HOVL 5M5YL 3RZDL 5IYDL 2R7ZL 2R93L 3GTQL 5IYBL 5M5WL 4A3JL 3S16L 1K83L 3S14L 4BXXL 4A3DL 1I50L 4AYBP 3GTLL 2NVYL 1Y1WL 5IP9L 3S2HL 4A93L 3S1RL 4Y7NL 5FJ8L 1WCML 5C3EL 2VUML
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IYC L;  5IP7 L;  3M3Y L;  3PO2 L;  5M3F L;  2NVT L;  4A3B L;  4QIW P;  2PMZ P;  2WB1 P;  1TWH L;  4A3L L;  1Y1V L;  1I6H L;  3S1Q L;  1TWC L;  4BBS L;  3GTM L;  1I3Q L;  3RZO L;  4Y52 L;  4BY1 L;  3GTK L;  4A3C L;  3HKZ P;  2E2H L;  2NVQ L;  4A3G L;  2NVX L;  2JA8 L;  4A3E L;  3S17 L;  4BBR L;  1R9T L;  4BY7 L;  3S15 L;  3HOW L;  2YU9 L;  3HOX L;  3K7A L;  3CQZ L;  2B63 L;  5C4J L;  2Y0S P;  3GTO L;  3H0G L;  4C3H L;  3GTJ L;  2E2J L;  3GTG L;  5M3M L;  2WAQ P;  3S1N L;  3FKI L;  2JA7 L;  4A3M L;  5M5X L;  5C4X L;  1TWA L;  4A3K L;  4C3I L;  4C3J L;  3M4O L;  3S1M L;  1TWG L;  3S2D L;  2R92 L;  3H3V M;  4C2M 1;  3HOZ L;  1TWF L;  5C44 L;  2JA6 L;  3HOU L;  4A3I L;  5FLM L;  3HOY L;  4X6A L;  3GTP L;  4A3F L;  2E2I L;  3PO3 L;  3I4M L;  3I4N L;  1SFO L;  2JA5 L;  3HOV L;  5M5Y L;  3RZD L;  5IYD L;  2R7Z L;  2R93 L;  3GTQ L;  5IYB L;  5M5W L;  4A3J L;  3S16 L;  1K83 L;  3S14 L;  4BXX L;  4A3D L;  1I50 L;  4AYB P;  3GTL L;  2NVY L;  1Y1W L;  5IP9 L;  3S2H L;  4A93 L;  3S1R L;  4Y7N L;  5FJ8 L;  1WCM L;  5C3E L;  2VUM L; 
#chains in the Genus database with same CATH topology
 1LTL A;  1C09 A;  4AR4 A;  3PO2 L;  2NVT L;  3PIP 1;  2WB1 P;  3RZ6 A;  3LWO B;  1I3Q L;  3LPE B;  1IU6 A;  4Y52 L;  4XGH A;  4POG A;  5MFZ A;  3H9B A;  3HKZ P;  4JAF A;  4TPU A;  5JVH 1;  4ME3 A;  4A3E L;  2V0E A;  3HOW L;  2YU9 L;  3H97 A;  4YWL A;  1ZRP A;  3GTG L;  3J7Y 1;  2WAQ P;  5DM6 1;  5GAE c;  4UY8 1;  3NFP I;  3KYU A;  1SMU A;  2NYD A;  1TWA L;  5MGN A;  4A3K L;  1VCX A;  8RXN A;  5RXN A;  2MS3 A;  2A6H D;  4XXB B;  3S2D L;  1JYB A;  3LWP B;  2L0Z A;  2PVX A;  4AR5 A;  2JA6 L;  4A3I L;  1IU5 A;  4TVM A;  4JAG A;  3HOY L;  4X6A L;  1F4L A;  4AR3 A;  1VZG A;  4A3F L;  2E2I L;  3PO3 L;  2HVY C;  1IRO A;  2PVE A;  1SFO L;  2B5I D;  1VZH A;  1T9P A;  2PSM C;  1R0J A;  3RZT A;  3GTQ L;  2KKD A;  3H9C A;  2XJP A;  3LNL A;  3P2A A;  3VPB E;  4A3D L;  3GTL L;  4AYB P;  1IW7 D;  4AI0 A;  1B13 A;  4JAE A;  4K9F A;  4Y7N L;  3LWV B;  1T9O A;  1WCM L;  3MSU A;  2VUM L;  1BE7 A;  5IYC L;  3J7Z 1;  5M3F L;  1B71 A;  7RXN A;  3B08 B;  4ZN1 B;  1BFY A;  4A3L L;  1SMW A;  1Y1V L;  1PFU A;  2XJS A;  4BBS L;  3RZO L;  4BY1 L;  1R0H A;  1PFW A;  1RDG A;  1B2O A;  3ZG6 A;  3HAX C;  4A3G L;  1RYT A;  2KN9 A;  2NVX L;  3JR7 A;  3KYW A;  4AHY A;  3S15 L;  1WJV A;  3KYY A;  3HOX L;  5C4J L;  2Y0S P;  3PZA A;  2E2J L;  1RB9 A;  3H99 A;  3K35 A;  2PPT A;  2EY4 E;  3S1N L;  4AR6 A;  1YV1 A;  3KYV A;  3B0A B;  2JA7 L;  5GAD c;  2CKC A;  1BQ9 A;  3IU3 I;  3MPS A;  3M4O L;  3S1M L;  1FHM A;  1TWG L;  2LCQ A;  1CAA A;  2JI3 A;  1NXG A;  3RYG A;  2R92 L;  4E6Y A;  2M4Y A;  4G6B A;  4AHX A;  3HOZ L;  1TWF L;  5EIO C;  3WWL A;  3PIO 1;  2J9U B;  1R0G A;  3LWR B;  1YUZ A;  1LKO A;  2VL6 A;  1CAD A;  2C6B A;  2BE5 D;  4U67 1;  3S16 L;  3S14 L;  1T9Q A;  1BRF A;  2NVY L;  1Y1W L;  1IRN A;  5IP9 L;  1LKP A;  5C3E L;  3MQK B;  1YUX A;  1LKM A;  5IP7 L;  2V0F A;  4A3B L;  1B2J A;  3P8B A;  4QIW P;  2XJR A;  5AI3 A;  4AHW A;  3S1Q L;  1TWC L;  2A68 D;  1YK5 A;  1SMM A;  3QQC E;  2NVQ L;  1QCV A;  1Z92 B;  1OWC A;  2JA8 L;  4AI3 A;  4WFN 1;  4BBR L;  3HJW B;  2AYJ A;  4B8C D;  1R9T L;  1DVB A;  3KYX A;  2M6O A;  3CQZ L;  3GTJ L;  4V19 6;  5AI2 A;  5AN9 H;  4AHZ A;  2XJV A;  4LHL A;  3FKI L;  5C4X L;  1QYB A;  2DSX A;  1QQT A;  4GS7 D;  4C3I L;  5DM7 1;  2M6P A;  2CKA A;  2ERJ A;  5IY0 A;  5C44 L;  2JI2 A;  2AUS B;  1PFV A;  1RWD A;  3GTP L;  1RDV A;  3PWF A;  1DX8 A;  2ERS A;  3SS2 A;  2JA5 L;  5M5Y L;  5JVG 1;  3RZD L;  5IYD L;  2R7Z L;  4LHN A;  5IYB L;  2A6E D;  4A3J L;  1K83 L;  6RXN A;  4ZN3 B;  1I50 L;  1R0F A;  4A93 L;  2APO B;  5FJ8 L;  5GAG c;  3A44 A;  2H12 A;  2V3B B;  1RYQ A;  3M3Y L;  2K2D A;  2PMZ P;  1TWH L;  2PYA A;  1OWB A;  4JAD A;  1I6H L;  3LWQ B;  2GMG A;  3GTM L;  3GTK L;  1BQ8 A;  4A3C L;  1VZI A;  2XJU A;  1PFY A;  2AQC A;  2E2H L;  2RDV A;  1NNQ A;  2QL0 A;  2M4V A;  2C6A A;  4AI1 A;  5GAH c;  3S17 L;  1NXE A;  2ZIX A;  4AI2 A;  4BY7 L;  2RFK B;  3K7A L;  2B63 L;  2CR8 A;  3GTO L;  3H0G L;  4C3H L;  2Z3Q B;  5M3M L;  1S30 A;  3PL5 A;  4A3M L;  1R0I A;  5M5X L;  3PKJ A;  4C3J L;  3QVD A;  3H3V M;  4C2M 1;  3HJY B;  4RXN A;  1FHH A;  1PZX A;  2Z3R B;  1S24 A;  1H7V A;  3HOU L;  5MLC 3;  5FLM L;  1P7P A;  3FDJ A;  2XJQ A;  5K2M E;  1YK4 A;  2HR5 A;  5EIN C;  3I4M L;  3WWN B;  3I4N L;  2A69 D;  3PKI A;  3HOV L;  4POF A;  1E8J A;  2R93 L;  2XJT A;  5MF6 A;  5M5W L;  5MFP A;  4BXX L;  5H1S c;  3S2H L;  1S2Z A;  3S1R L;  2O5J D;  2JI1 A;  4YWM A;  1ODH A; 
#chains in the Genus database with same CATH homology
 5IYC L;  5IP7 L;  3M3Y L;  3PO2 L;  5M3F L;  2NVT L;  4A3B L;  4QIW P;  2PMZ P;  2WB1 P;  1TWH L;  4A3L L;  1Y1V L;  1I6H L;  3S1Q L;  1TWC L;  4BBS L;  3GTM L;  1I3Q L;  3RZO L;  4Y52 L;  4BY1 L;  3GTK L;  4A3C L;  3HKZ P;  2E2H L;  2NVQ L;  4A3G L;  2NVX L;  2JA8 L;  4A3E L;  3S17 L;  4BBR L;  1R9T L;  4BY7 L;  3S15 L;  3HOW L;  2YU9 L;  3HOX L;  3K7A L;  3CQZ L;  2B63 L;  5C4J L;  2Y0S P;  3GTO L;  3H0G L;  4C3H L;  3GTJ L;  2E2J L;  3GTG L;  5M3M L;  2WAQ P;  3S1N L;  3FKI L;  2JA7 L;  4A3M L;  5M5X L;  5C4X L;  1TWA L;  4A3K L;  4C3I L;  4C3J L;  3M4O L;  3S1M L;  1TWG L;  3S2D L;  2R92 L;  3H3V M;  4C2M 1;  3HOZ L;  1TWF L;  5C44 L;  2JA6 L;  3HOU L;  4A3I L;  5FLM L;  3HOY L;  4X6A L;  3GTP L;  4A3F L;  2E2I L;  3PO3 L;  3I4M L;  3I4N L;  1SFO L;  2JA5 L;  3HOV L;  5M5Y L;  3RZD L;  5IYD L;  2R7Z L;  2R93 L;  3GTQ L;  5IYB L;  5M5W L;  4A3J L;  3S16 L;  1K83 L;  3S14 L;  4BXX L;  4A3D L;  1I50 L;  4AYB P;  3GTL L;  2NVY L;  1Y1W L;  5IP9 L;  3S2H L;  4A93 L;  3S1R L;  4Y7N L;  5FJ8 L;  1WCM L;  5C3E L;  2VUM L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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