2QJCA

Crystal structure of a putative diadenosine tetraphosphatase
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
242
structure length
222
Chain Sequence
YANVVTLPNVTGRVIIVGDIHGCRAQLEDLLRAVSFKQGSDTLVAVGDLVNKGPDSFGVVRLLKRLGAYSVLGNHDAKLLKLVKKLSLAPLAQSIPTDVETYLSQLPHIIRIPAHNVMVAHAGLHPQRPVDRQYEDEVTTMRNLIEKVTLTATEETNDGGKPWASMWRGPETVVFGHDARRGLQEQYKPLAIGLDSRCVYGGRLSAAVFPGGCIISVPGWNG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Trypanosoma brucei
publication title Structural genomics of protein phosphatases.
pubmed doi rcsb
molecule keywords Diadenosine tetraphosphatase, putative
total genus 63
structure length 222
sequence length 242
ec nomenclature ec 3.6.1.41: Bis(5'-nucleosyl)-tetraphosphatase (symmetrical).
pdb deposition date 2007-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2qjcA00
3HVQA 3H67A 3C9FA 4FBKA 3N5UA 2QFPA 4V0XA 3THNA 2O8AA 2YVTA 2GJUA 3C5WC 4ZVZA 4DHLA 1II7A 4O43A 1XM7A 3EGGA 1S3NA 3IB7A 4LACC 1USHA 4V0WA 2BDXA 2NYMC 1UF3A 2JOGA 1OI8A 2IAEC 2WDEA 3AV0A 3CK2A 3LL8A 5B8IA 2WDFA 4LU9A 1S70A 2Q8UA 4UT2A 3PSNA 1S3LA 5J28A 3QFKA 2Z72A 3QFMA 3ZU0A 5GTUA 1TCOA 3V4YA 3H63A 3DSCA 1UTEA 3GVEA 2Z06A 1U32A 4I5NC 4F0ZA 4JA7A 4M0VA 3P71C 3RL3A 2ZBMA 2WDCA 2DFJA 2BQ8X 3E7BA 2USHA 1SU1A 4H2GA 4MOVA 4FBQA 3ZTVA 1V73A 2NXFA 1G5BA 2AHDA 2QJCA 4DT2A 3H69A 1WAO1 2QFRA 3QFOA 4G9JA 4O5GA 1FJMA 4IL1A 4KKZA 4JA9A 4LTYA 1JK7A 4V0VA 5EQVA 4ORAA 5F3WA 3IVDA 2XMOA 1QHWA 1Z2XA 4Q7FA 1KBPA 3DW8C 3FGAC 4FCXA 1QFCA 3THOB 4J6OA 1HO5A 4O24A 2O8GA 2Z1AA 4H2FA 4DSYA 3QFNA 5JPFA 4HD0A 5INBA 2KKNA 1HP1A 3K7WC 4H1YP 3ICFA 5DNYA 4FBWA 2WDDA 3H62B 4TUGA 3AUZA 1OIEA 2R17A 4H2IA 3H60A 1M63A 1S95A 4TUIA 1NNWA 1XZWA 4I5LC 4KBPA 4UT3A 2NPPC 2NYLC 3TGHA 1HPUA 3T1IA 3RL4A 4ORBA 3QG5C 3H68A 4O4KA 3RL5A 1MF8A 5JPEA 1T71A 3K7VC 1T70A 1S8EA 4MP0A 1Z2WA 1IT6A 2HYPA 3RQZA 3KBPA 3IVEA 4WWLA 2BCDA 3E7AA 4H1SA 4YKEA 3IB8A 3H61A 3JYFA 4ORCA 1OIDA 5IOHA 2IE4C 4UT3B 1AUIA 2HYOA 1W24A 2A22A 1S3MA 3H64A 4IYPC 1WARA 4ZX2A 3EGHA 4NZVA 2P6BA 5C1VA 2HY1A 4XPNA 4MOYA 4H2BA 4UWQA 2CV9A 3DSDA 3H66A 3PSOA 4B2OA 5HPEA 2IE3C 5JJTA 4OR9A
chains in the Genus database with same CATH superfamily
3HVQA 3H67A 3C9FA 4FBKA 3N5UA 2QFPA 4V0XA 3THNA 2O8AA 2YVTA 2GJUA 3C5WC 4ZVZA 4DHLA 1II7A 4O43A 1XM7A 3EGGA 1S3NA 3IB7A 4LACC 1USHA 4V0WA 2BDXA 2NYMC 1UF3A 2JOGA 1OI8A 2IAEC 2WDEA 3AV0A 3CK2A 3LL8A 5B8IA 2WDFA 4LU9A 1S70A 2Q8UA 4UT2A 3PSNA 1S3LA 5J28A 3QFKA 2Z72A 3QFMA 3ZU0A 5GTUA 1TCOA 2DXNA 3V4YA 3H63A 3DSCA 1UTEA 3E0JA 3GVEA 2Z06A 1U32A 2ZO9B 4I5NC 4F0ZA 4JA7A 4M0VA 3P71C 3RL3A 3D03A 2ZBMA 2WDCA 2DFJA 2BQ8X 3E7BA 2USHA 1SU1A 4H2GA 4MOVA 4FBQA 3ZTVA 1V73A 2NXFA 3FLOA 1G5BA 2AHDA 2QJCA 4DT2A 3H69A 1WAO1 2QFRA 3QFOA 4G9JA 4O5GA 1FJMA 4IL1A 4KKZA 4JA9A 4LTYA 1JK7A 4V0VA 5EQVA 4ORAA 5F3WA 3IVDA 2XMOA 1QHWA 1Z2XA 4Q7FA 1KBPA 2DXLA 3DW8C 3FGAC 4FCXA 1QFCA 3THOB 4J6OA 2YEQA 1HO5A 4O24A 2O8GA 2Z1AA 4H2FA 4DSYA 3QFNA 5JPFA 4HD0A 5INBA 2KKNA 1HP1A 3K7WC 4H1YP 3ICFA 5DNYA 4FBWA 2WDDA 3H62B 4TUGA 3AUZA 1OIEA 2R17A 4H2IA 3H60A 1M63A 1S95A 4TUIA 1NNWA 1XZWA 4I5LC 4KBPA 4UT3A 2NPPC 2NYLC 3TGHA 1HPUA 3T1IA 3RL4A 4ORBA 3QG5C 3H68A 4O4KA 3RL5A 1MF8A 5JPEA 1T71A 3K7VC 1T70A 1S8EA 2ZOAA 1Z2WA 1IT6A 4MP0A 2HYPA 3RQZA 3KBPA 3IVEA 4WWLA 2BCDA 3E7AA 4H1SA 4YKEA 3IB8A 3H61A 3JYFA 4ORCA 1OIDA 5IOHA 2IE4C 4UT3B 1AUIA 2HYOA 1W24A 2A22A 1S3MA 3H64A 4IYPC 1WARA 4ZX2A 3EGHA 4NZVA 2P6BA 5C1VA 2HY1A 4XPNA 4MOYA 4H2BA 4UWQA 2CV9A 3DSDA 3H66A 3PSOA 4B2OA 5HPEA 2IE3C 5JJTA 4OR9A
chains in the Genus database with same CATH topology
3HVQA 3H67A 3C9FA 4FBKA 3N5UA 2QFPA 4V0XA 3THNA 2O8AA 2YVTA 2GJUA 3C5WC 4ZVZA 4DHLA 1II7A 4O43A 1XM7A 3EGGA 1S3NA 3IB7A 4LACC 1USHA 4V0WA 2BDXA 2NYMC 1UF3A 2JOGA 1OI8A 2IAEC 2WDEA 3AV0A 3CK2A 3LL8A 5B8IA 2WDFA 4LU9A 1S70A 2Q8UA 4UT2A 3PSNA 1S3LA 5J28A 3QFKA 2Z72A 3QFMA 3ZU0A 5GTUA 1TCOA 2DXNA 3V4YA 3H63A 3DSCA 1UTEA 3E0JA 3GVEA 2Z06A 1U32A 2ZO9B 4I5NC 4F0ZA 4JA7A 4M0VA 3P71C 3RL3A 3D03A 2ZBMA 2WDCA 2DFJA 2BQ8X 3E7BA 2USHA 1SU1A 4H2GA 4MOVA 4FBQA 3ZTVA 1V73A 2NXFA 3FLOA 1G5BA 2AHDA 2QJCA 4DT2A 3H69A 1WAO1 2QFRA 3QFOA 4G9JA 4O5GA 1FJMA 4IL1A 4KKZA 4JA9A 4LTYA 1JK7A 4V0VA 5EQVA 4ORAA 5F3WA 3IVDA 2XMOA 1QHWA 1Z2XA 4Q7FA 1KBPA 2DXLA 3DW8C 3FGAC 4FCXA 1QFCA 3THOB 4J6OA 2YEQA 1HO5A 4O24A 2O8GA 2Z1AA 4H2FA 4DSYA 3QFNA 5JPFA 4HD0A 5INBA 2KKNA 1HP1A 3K7WC 4H1YP 3ICFA 5DNYA 4FBWA 2WDDA 3H62B 4TUGA 3AUZA 1OIEA 2R17A 4H2IA 3H60A 1M63A 1S95A 4TUIA 1NNWA 1XZWA 4I5LC 4KBPA 4UT3A 2NPPC 2NYLC 3TGHA 1HPUA 3T1IA 3RL4A 4ORBA 3QG5C 3H68A 4O4KA 3RL5A 1MF8A 5JPEA 1T71A 3K7VC 1T70A 1S8EA 2ZOAA 1Z2WA 1IT6A 4MP0A 2HYPA 3RQZA 3KBPA 3IVEA 4WWLA 2BCDA 3E7AA 4H1SA 4YKEA 3IB8A 3H61A 3JYFA 4ORCA 1OIDA 5IOHA 2IE4C 4UT3B 1AUIA 2HYOA 1W24A 2A22A 1S3MA 3H64A 4IYPC 1WARA 4ZX2A 3EGHA 4NZVA 2P6BA 5C1VA 2HY1A 4XPNA 4MOYA 4H2BA 4UWQA 2CV9A 3DSDA 3H66A 3PSOA 4B2OA 5HPEA 2IE3C 5JJTA 4OR9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HVQ A;  3H67 A;  3C9F A;  4FBK A;  3N5U A;  2QFP A;  4V0X A;  3THN A;  2O8A A;  2YVT A;  2GJU A;  3C5W C;  4ZVZ A;  4DHL A;  1II7 A;  4O43 A;  1XM7 A;  3EGG A;  1S3N A;  3IB7 A;  4LAC C;  1USH A;  4V0W A;  2BDX A;  2NYM C;  1UF3 A;  2JOG A;  1OI8 A;  2IAE C;  2WDE A;  3AV0 A;  3CK2 A;  3LL8 A;  5B8I A;  2WDF A;  4LU9 A;  1S70 A;  2Q8U A;  4UT2 A;  3PSN A;  1S3L A;  5J28 A;  3QFK A;  2Z72 A;  3QFM A;  3ZU0 A;  5GTU A;  1TCO A;  3V4Y A;  3H63 A;  3DSC A;  1UTE A;  3GVE A;  2Z06 A;  1U32 A;  4I5N C;  4F0Z A;  4JA7 A;  4M0V A;  3P71 C;  3RL3 A;  2ZBM A;  2WDC A;  2DFJ A;  2BQ8 X;  3E7B A;  2USH A;  1SU1 A;  4H2G A;  4MOV A;  4FBQ A;  3ZTV A;  1V73 A;  2NXF A;  1G5B A;  2AHD A;  2QJC A;  4DT2 A;  3H69 A;  1WAO 1;  2QFR A;  3QFO A;  4G9J A;  4O5G A;  1FJM A;  4IL1 A;  4KKZ A;  4JA9 A;  4LTY A;  1JK7 A;  4V0V A;  5EQV A;  4ORA A;  5F3W A;  3IVD A;  2XMO A;  1QHW A;  1Z2X A;  4Q7F A;  1KBP A;  3DW8 C;  3FGA C;  4FCX A;  1QFC A;  3THO B;  4J6O A;  1HO5 A;  4O24 A;  2O8G A;  2Z1A A;  4H2F A;  4DSY A;  3QFN A;  5JPF A;  4HD0 A;  5INB A;  2KKN A;  1HP1 A;  3K7W C;  4H1Y P;  3ICF A;  5DNY A;  4FBW A;  2WDD A;  3H62 B;  4TUG A;  3AUZ A;  1OIE A;  2R17 A;  4H2I A;  3H60 A;  1M63 A;  1S95 A;  4TUI A;  1NNW A;  1XZW A;  4I5L C;  4KBP A;  4UT3 A;  2NPP C;  2NYL C;  3TGH A;  1HPU A;  3T1I A;  3RL4 A;  4ORB A;  3QG5 C;  3H68 A;  4O4K A;  3RL5 A;  1MF8 A;  5JPE A;  1T71 A;  3K7V C;  1T70 A;  1S8E A;  4MP0 A;  1Z2W A;  1IT6 A;  2HYP A;  3RQZ A;  3KBP A;  3IVE A;  4WWL A;  2BCD A;  3E7A A;  4H1S A;  4YKE A;  3IB8 A;  3H61 A;  3JYF A;  4ORC A;  1OID A;  5IOH A;  2IE4 C;  4UT3 B;  1AUI A;  2HYO A;  1W24 A;  2A22 A;  1S3M A;  3H64 A;  4IYP C;  1WAR A;  4ZX2 A;  3EGH A;  4NZV A;  2P6B A;  5C1V A;  2HY1 A;  4XPN A;  4MOY A;  4H2B A;  4UWQ A;  2CV9 A;  3DSD A;  3H66 A;  3PSO A;  4B2O A;  5HPE A;  2IE3 C;  5JJT A;  4OR9 A; 
#chains in the Genus database with same CATH topology
 3HVQ A;  3H67 A;  3C9F A;  4FBK A;  3N5U A;  2QFP A;  4V0X A;  3THN A;  2O8A A;  2YVT A;  2GJU A;  3C5W C;  4ZVZ A;  4DHL A;  1II7 A;  4O43 A;  1XM7 A;  3EGG A;  1S3N A;  3IB7 A;  4LAC C;  1USH A;  4V0W A;  2BDX A;  2NYM C;  1UF3 A;  2JOG A;  1OI8 A;  2IAE C;  2WDE A;  3AV0 A;  3CK2 A;  3LL8 A;  5B8I A;  2WDF A;  4LU9 A;  1S70 A;  2Q8U A;  4UT2 A;  3PSN A;  1S3L A;  5J28 A;  3QFK A;  2Z72 A;  3QFM A;  3ZU0 A;  5GTU A;  1TCO A;  2DXN A;  3V4Y A;  3H63 A;  3DSC A;  1UTE A;  3E0J A;  3GVE A;  2Z06 A;  1U32 A;  2ZO9 B;  4I5N C;  4F0Z A;  4JA7 A;  4M0V A;  3P71 C;  3RL3 A;  3D03 A;  2ZBM A;  2WDC A;  2DFJ A;  2BQ8 X;  3E7B A;  2USH A;  1SU1 A;  4H2G A;  4MOV A;  4FBQ A;  3ZTV A;  1V73 A;  2NXF A;  3FLO A;  1G5B A;  2AHD A;  2QJC A;  4DT2 A;  3H69 A;  1WAO 1;  2QFR A;  3QFO A;  4G9J A;  4O5G A;  1FJM A;  4IL1 A;  4KKZ A;  4JA9 A;  4LTY A;  1JK7 A;  4V0V A;  5EQV A;  4ORA A;  5F3W A;  3IVD A;  2XMO A;  1QHW A;  1Z2X A;  4Q7F A;  1KBP A;  2DXL A;  3DW8 C;  3FGA C;  4FCX A;  1QFC A;  3THO B;  4J6O A;  2YEQ A;  1HO5 A;  4O24 A;  2O8G A;  2Z1A A;  4H2F A;  4DSY A;  3QFN A;  5JPF A;  4HD0 A;  5INB A;  2KKN A;  1HP1 A;  3K7W C;  4H1Y P;  3ICF A;  5DNY A;  4FBW A;  2WDD A;  3H62 B;  4TUG A;  3AUZ A;  1OIE A;  2R17 A;  4H2I A;  3H60 A;  1M63 A;  1S95 A;  4TUI A;  1NNW A;  1XZW A;  4I5L C;  4KBP A;  4UT3 A;  2NPP C;  2NYL C;  3TGH A;  1HPU A;  3T1I A;  3RL4 A;  4ORB A;  3QG5 C;  3H68 A;  4O4K A;  3RL5 A;  1MF8 A;  5JPE A;  1T71 A;  3K7V C;  1T70 A;  1S8E A;  2ZOA A;  1Z2W A;  1IT6 A;  4MP0 A;  2HYP A;  3RQZ A;  3KBP A;  3IVE A;  4WWL A;  2BCD A;  3E7A A;  4H1S A;  4YKE A;  3IB8 A;  3H61 A;  3JYF A;  4ORC A;  1OID A;  5IOH A;  2IE4 C;  4UT3 B;  1AUI A;  2HYO A;  1W24 A;  2A22 A;  1S3M A;  3H64 A;  4IYP C;  1WAR A;  4ZX2 A;  3EGH A;  4NZV A;  2P6B A;  5C1V A;  2HY1 A;  4XPN A;  4MOY A;  4H2B A;  4UWQ A;  2CV9 A;  3DSD A;  3H66 A;  3PSO A;  4B2O A;  5HPE A;  2IE3 C;  5JJT A;  4OR9 A; 
#chains in the Genus database with same CATH homology
 3HVQ A;  3H67 A;  3C9F A;  4FBK A;  3N5U A;  2QFP A;  4V0X A;  3THN A;  2O8A A;  2YVT A;  2GJU A;  3C5W C;  4ZVZ A;  4DHL A;  1II7 A;  4O43 A;  1XM7 A;  3EGG A;  1S3N A;  3IB7 A;  4LAC C;  1USH A;  4V0W A;  2BDX A;  2NYM C;  1UF3 A;  2JOG A;  1OI8 A;  2IAE C;  2WDE A;  3AV0 A;  3CK2 A;  3LL8 A;  5B8I A;  2WDF A;  4LU9 A;  1S70 A;  2Q8U A;  4UT2 A;  3PSN A;  1S3L A;  5J28 A;  3QFK A;  2Z72 A;  3QFM A;  3ZU0 A;  5GTU A;  1TCO A;  2DXN A;  3V4Y A;  3H63 A;  3DSC A;  1UTE A;  3E0J A;  3GVE A;  2Z06 A;  1U32 A;  2ZO9 B;  4I5N C;  4F0Z A;  4JA7 A;  4M0V A;  3P71 C;  3RL3 A;  3D03 A;  2ZBM A;  2WDC A;  2DFJ A;  2BQ8 X;  3E7B A;  2USH A;  1SU1 A;  4H2G A;  4MOV A;  4FBQ A;  3ZTV A;  1V73 A;  2NXF A;  3FLO A;  1G5B A;  2AHD A;  2QJC A;  4DT2 A;  3H69 A;  1WAO 1;  2QFR A;  3QFO A;  4G9J A;  4O5G A;  1FJM A;  4IL1 A;  4KKZ A;  4JA9 A;  4LTY A;  1JK7 A;  4V0V A;  5EQV A;  4ORA A;  5F3W A;  3IVD A;  2XMO A;  1QHW A;  1Z2X A;  4Q7F A;  1KBP A;  2DXL A;  3DW8 C;  3FGA C;  4FCX A;  1QFC A;  3THO B;  4J6O A;  2YEQ A;  1HO5 A;  4O24 A;  2O8G A;  2Z1A A;  4H2F A;  4DSY A;  3QFN A;  5JPF A;  4HD0 A;  5INB A;  2KKN A;  1HP1 A;  3K7W C;  4H1Y P;  3ICF A;  5DNY A;  4FBW A;  2WDD A;  3H62 B;  4TUG A;  3AUZ A;  1OIE A;  2R17 A;  4H2I A;  3H60 A;  1M63 A;  1S95 A;  4TUI A;  1NNW A;  1XZW A;  4I5L C;  4KBP A;  4UT3 A;  2NPP C;  2NYL C;  3TGH A;  1HPU A;  3T1I A;  3RL4 A;  4ORB A;  3QG5 C;  3H68 A;  4O4K A;  3RL5 A;  1MF8 A;  5JPE A;  1T71 A;  3K7V C;  1T70 A;  1S8E A;  2ZOA A;  1Z2W A;  1IT6 A;  4MP0 A;  2HYP A;  3RQZ A;  3KBP A;  3IVE A;  4WWL A;  2BCD A;  3E7A A;  4H1S A;  4YKE A;  3IB8 A;  3H61 A;  3JYF A;  4ORC A;  1OID A;  5IOH A;  2IE4 C;  4UT3 B;  1AUI A;  2HYO A;  1W24 A;  2A22 A;  1S3M A;  3H64 A;  4IYP C;  1WAR A;  4ZX2 A;  3EGH A;  4NZV A;  2P6B A;  5C1V A;  2HY1 A;  4XPN A;  4MOY A;  4H2B A;  4UWQ A;  2CV9 A;  3DSD A;  3H66 A;  3PSO A;  4B2O A;  5HPE A;  2IE3 C;  5JJT A;  4OR9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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