2QJCA

Crystal structure of a putative diadenosine tetraphosphatase
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
242
structure length
222
Chain Sequence
YANVVTLPNVTGRVIIVGDIHGCRAQLEDLLRAVSFKQGSDTLVAVGDLVNKGPDSFGVVRLLKRLGAYSVLGNHDAKLLKLVKKLSLAPLAQSIPTDVETYLSQLPHIIRIPAHNVMVAHAGLHPQRPVDRQYEDEVTTMRNLIEKVTLTATEETNDGGKPWASMWRGPETVVFGHDARRGLQEQYKPLAIGLDSRCVYGGRLSAAVFPGGCIISVPGWNG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structural genomics of protein phosphatases.
pubmed doi rcsb
molecule keywords Diadenosine tetraphosphatase, putative
molecule tags Hydrolase
source organism Trypanosoma brucei
total genus 63
structure length 222
sequence length 242
ec nomenclature ec 3.6.1.41: Bis(5'-nucleosyl)-tetraphosphatase (symmetrical).
pdb deposition date 2007-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2qjcA00
5JPEA 2XMOA 1JK7A 3K7VC 4O5GA 3H64A 3QFMA 4FCXA 4B2OA 5IOHA 2WDEA 1OIEA 4KBPA 1FJMA 2Z1AA 3QFOA 5JPFA 4FBWA 4H2BA 5HPEA 3IVDA 2IE3C 2WDFA 3H67A 3THOB 3E7AA 3ZTVA 3DW8C 4H2FA 2O8AA 2CV9A 3EGHA 3AV0A 4LTYA 1XZWA 4ORAA 3T1IA 1TCOA 2HY1A 2HYOA 1U32A 3QFKA 4F0ZA 2ZBMA 4HD0A 4ZVZA 2WDCA 5J28A 3H60A 4DT2A 4O24A 4O4KA 4MOYA 3H61A 2QJCA 3CK2A 4ORCA 3H66A 5EQVA 3E7BA 2NYMC 2BCDA 2Z06A 1S70A 3ZU0A 4OR9A 1S3NA 1WARA 3H62B 1OI8A 4H1YP 4V0WA 3FGAC 3TGHA 1QHWA 4G9JA 4DSYA 2USHA 4V0XA 1AUIA 3QG5C 3RL3A 4V0VA 3EGGA 1S3MA 1UF3A 4LU9A 3RQZA 1KBPA 4KKZA 4O43A 3V4YA 2WDDA 3PSOA 3GVEA 3KBPA 4H2GA 2YVTA 5B8IA 4I5LC 2JOGA 1XM7A 1WAO1 2IE4C 2Q8UA 1USHA 1HO5A 1V73A 1MF8A 1II7A 1S3LA 1UTEA 1NNWA 2P6BA 2Z72A 3IB8A 3IVEA 2R17A 3IB7A 4YKEA 1S8EA 5DNYA 3HVQA 4FBKA 1G5BA 1Z2WA 1T70A 3C9FA 4JA9A 4Q7FA 4H1SA 5GTUA 1S95A 1OIDA 3K7WC 4MOVA 1QFCA 1M63A 4XPNA 3H63A 4NZVA 4FBQA 4TUIA 4ZX2A 2BDXA 2O8GA 4UWQA 3THNA 3N5UA 4UT3A 4LACC 2NYLC 1IT6A 5INBA 4H2IA 3LL8A 3H69A 3P71C 2QFRA 5C1VA 4M0VA 4UT2A 3AUZA 4ORBA 4TUGA 2NXFA 4IYPC 4I5NC 3PSNA 1SU1A 1HP1A 2GJUA 2DFJA 1HPUA 4DHLA 5F3WA 1Z2XA 1W24A 3RL5A 2QFPA 1T71A 2BQ8X 3QFNA 3JYFA 4UT3B 4JA7A 2NPPC 3H68A 4MP0A 2AHDA 3DSCA 4IL1A 2KKNA 4WWLA 3RL4A 2IAEC 3ICFA 5JJTA 4J6OA 2HYPA 2A22A 3DSDA 3C5WC
chains in the Genus database with same CATH superfamily
5JPEA 2XMOA 1JK7A 3K7VC 4O5GA 3H64A 3QFMA 4FCXA 4B2OA 5IOHA 2WDEA 1OIEA 4KBPA 1FJMA 2Z1AA 3QFOA 5JPFA 4FBWA 4H2BA 5HPEA 3IVDA 2IE3C 2DXLA 2WDFA 3H67A 3THOB 3E7AA 3ZTVA 3DW8C 4H2FA 2O8AA 2CV9A 3EGHA 3AV0A 3D03A 4LTYA 1XZWA 4ORAA 3T1IA 1TCOA 2HY1A 2HYOA 1U32A 3QFKA 4F0ZA 2ZBMA 4HD0A 4ZVZA 2WDCA 5J28A 3H60A 4DT2A 4O24A 4O4KA 4MOYA 3H61A 2QJCA 3CK2A 4ORCA 3H66A 5EQVA 3E7BA 2NYMC 2BCDA 2Z06A 1S70A 3ZU0A 4OR9A 1S3NA 1WARA 3H62B 1OI8A 4H1YP 4V0WA 3FGAC 3TGHA 1QHWA 4G9JA 4DSYA 2YEQA 2USHA 4V0XA 1AUIA 3QG5C 3RL3A 4V0VA 3EGGA 1S3MA 1UF3A 4LU9A 3RQZA 1KBPA 4KKZA 4O43A 3V4YA 2WDDA 3PSOA 3GVEA 3KBPA 3FLOA 4H2GA 2YVTA 5B8IA 4I5LC 2JOGA 1XM7A 1WAO1 2IE4C 2Q8UA 1USHA 1HO5A 1V73A 1MF8A 1II7A 1S3LA 1UTEA 1NNWA 2P6BA 2Z72A 3IB8A 3IVEA 2R17A 3IB7A 4YKEA 3E0JA 1S8EA 5DNYA 3HVQA 4FBKA 1G5BA 1Z2WA 1T70A 3C9FA 4JA9A 4Q7FA 4H1SA 5GTUA 1S95A 1OIDA 3K7WC 4MOVA 1QFCA 1M63A 4XPNA 3H63A 4NZVA 4FBQA 4TUIA 4ZX2A 2BDXA 2O8GA 2ZO9B 4UWQA 3N5UA 3THNA 4UT3A 4LACC 2NYLC 1IT6A 5INBA 4H2IA 3LL8A 3H69A 3P71C 2QFRA 5C1VA 4M0VA 4UT2A 3AUZA 4ORBA 4TUGA 2NXFA 4IYPC 4I5NC 3PSNA 1SU1A 1HP1A 2DXNA 2GJUA 2DFJA 1HPUA 4DHLA 5F3WA 1Z2XA 1W24A 3RL5A 2QFPA 1T71A 2BQ8X 3QFNA 3JYFA 4UT3B 4JA7A 2NPPC 3H68A 4MP0A 2AHDA 3DSCA 4IL1A 2KKNA 2ZOAA 4WWLA 3RL4A 2IAEC 3ICFA 5JJTA 4J6OA 2HYPA 2A22A 3DSDA 3C5WC
chains in the Genus database with same CATH topology
5JPEA 2XMOA 1JK7A 3K7VC 4O5GA 3H64A 3QFMA 4FCXA 4B2OA 5IOHA 2WDEA 1OIEA 4KBPA 1FJMA 2Z1AA 3QFOA 5JPFA 4FBWA 4H2BA 5HPEA 3IVDA 2IE3C 2DXLA 2WDFA 3H67A 3THOB 3E7AA 3ZTVA 3DW8C 4H2FA 2O8AA 2CV9A 3EGHA 3AV0A 3D03A 4LTYA 1XZWA 4ORAA 3T1IA 1TCOA 2HY1A 2HYOA 1U32A 3QFKA 4F0ZA 2ZBMA 4HD0A 4ZVZA 2WDCA 5J28A 3H60A 4DT2A 4O24A 4O4KA 4MOYA 3H61A 2QJCA 3CK2A 4ORCA 3H66A 5EQVA 3E7BA 2NYMC 2BCDA 2Z06A 1S70A 3ZU0A 4OR9A 1S3NA 1WARA 3H62B 1OI8A 4H1YP 4V0WA 3FGAC 3TGHA 1QHWA 4G9JA 4DSYA 2YEQA 2USHA 4V0XA 1AUIA 3QG5C 3RL3A 4V0VA 3EGGA 1S3MA 1UF3A 4LU9A 3RQZA 1KBPA 4KKZA 4O43A 3V4YA 2WDDA 3PSOA 3GVEA 3KBPA 3FLOA 4H2GA 2YVTA 5B8IA 4I5LC 2JOGA 1XM7A 1WAO1 2IE4C 2Q8UA 1USHA 1HO5A 1V73A 1MF8A 1II7A 1S3LA 1UTEA 1NNWA 2P6BA 2Z72A 3IB8A 3IVEA 2R17A 3IB7A 4YKEA 3E0JA 1S8EA 5DNYA 3HVQA 4FBKA 1G5BA 1Z2WA 1T70A 3C9FA 4JA9A 4Q7FA 4H1SA 5GTUA 1S95A 1OIDA 3K7WC 4MOVA 1QFCA 1M63A 4XPNA 3H63A 4NZVA 4FBQA 4TUIA 4ZX2A 2BDXA 2O8GA 2ZO9B 4UWQA 3N5UA 3THNA 4UT3A 4LACC 2NYLC 1IT6A 5INBA 4H2IA 3LL8A 3H69A 3P71C 2QFRA 5C1VA 4M0VA 4UT2A 3AUZA 4ORBA 4TUGA 2NXFA 4IYPC 4I5NC 3PSNA 1SU1A 1HP1A 2DXNA 2GJUA 2DFJA 1HPUA 4DHLA 5F3WA 1Z2XA 1W24A 3RL5A 2QFPA 1T71A 2BQ8X 3QFNA 3JYFA 4UT3B 4JA7A 2NPPC 3H68A 4MP0A 2AHDA 3DSCA 4IL1A 2KKNA 2ZOAA 4WWLA 3RL4A 2IAEC 3ICFA 5JJTA 4J6OA 2HYPA 2A22A 3DSDA 3C5WC
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 5JPE A;  2XMO A;  1JK7 A;  3K7V C;  4O5G A;  3H64 A;  3QFM A;  4FCX A;  4B2O A;  5IOH A;  2WDE A;  1OIE A;  4KBP A;  1FJM A;  2Z1A A;  3QFO A;  5JPF A;  4FBW A;  4H2B A;  5HPE A;  3IVD A;  2IE3 C;  2WDF A;  3H67 A;  3THO B;  3E7A A;  3ZTV A;  3DW8 C;  4H2F A;  2O8A A;  2CV9 A;  3EGH A;  3AV0 A;  4LTY A;  1XZW A;  4ORA A;  3T1I A;  1TCO A;  2HY1 A;  2HYO A;  1U32 A;  3QFK A;  4F0Z A;  2ZBM A;  4HD0 A;  4ZVZ A;  2WDC A;  5J28 A;  3H60 A;  4DT2 A;  4O24 A;  4O4K A;  4MOY A;  3H61 A;  2QJC A;  3CK2 A;  4ORC A;  3H66 A;  5EQV A;  3E7B A;  2NYM C;  2BCD A;  2Z06 A;  1S70 A;  3ZU0 A;  4OR9 A;  1S3N A;  1WAR A;  3H62 B;  1OI8 A;  4H1Y P;  4V0W A;  3FGA C;  3TGH A;  1QHW A;  4G9J A;  4DSY A;  2USH A;  4V0X A;  1AUI A;  3QG5 C;  3RL3 A;  4V0V A;  3EGG A;  1S3M A;  1UF3 A;  4LU9 A;  3RQZ A;  1KBP A;  4KKZ A;  4O43 A;  3V4Y A;  2WDD A;  3PSO A;  3GVE A;  3KBP A;  4H2G A;  2YVT A;  5B8I A;  4I5L C;  2JOG A;  1XM7 A;  1WAO 1;  2IE4 C;  2Q8U A;  1USH A;  1HO5 A;  1V73 A;  1MF8 A;  1II7 A;  1S3L A;  1UTE A;  1NNW A;  2P6B A;  2Z72 A;  3IB8 A;  3IVE A;  2R17 A;  3IB7 A;  4YKE A;  1S8E A;  5DNY A;  3HVQ A;  4FBK A;  1G5B A;  1Z2W A;  1T70 A;  3C9F A;  4JA9 A;  4Q7F A;  4H1S A;  5GTU A;  1S95 A;  1OID A;  3K7W C;  4MOV A;  1QFC A;  1M63 A;  4XPN A;  3H63 A;  4NZV A;  4FBQ A;  4TUI A;  4ZX2 A;  2BDX A;  2O8G A;  4UWQ A;  3THN A;  3N5U A;  4UT3 A;  4LAC C;  2NYL C;  1IT6 A;  5INB A;  4H2I A;  3LL8 A;  3H69 A;  3P71 C;  2QFR A;  5C1V A;  4M0V A;  4UT2 A;  3AUZ A;  4ORB A;  4TUG A;  2NXF A;  4IYP C;  4I5N C;  3PSN A;  1SU1 A;  1HP1 A;  2GJU A;  2DFJ A;  1HPU A;  4DHL A;  5F3W A;  1Z2X A;  1W24 A;  3RL5 A;  2QFP A;  1T71 A;  2BQ8 X;  3QFN A;  3JYF A;  4UT3 B;  4JA7 A;  2NPP C;  3H68 A;  4MP0 A;  2AHD A;  3DSC A;  4IL1 A;  2KKN A;  4WWL A;  3RL4 A;  2IAE C;  3ICF A;  5JJT A;  4J6O A;  2HYP A;  2A22 A;  3DSD A;  3C5W C; 
#chains in the Genus database with same CATH topology
 5JPE A;  2XMO A;  1JK7 A;  3K7V C;  4O5G A;  3H64 A;  3QFM A;  4FCX A;  4B2O A;  5IOH A;  2WDE A;  1OIE A;  4KBP A;  1FJM A;  2Z1A A;  3QFO A;  5JPF A;  4FBW A;  4H2B A;  5HPE A;  3IVD A;  2IE3 C;  2DXL A;  2WDF A;  3H67 A;  3THO B;  3E7A A;  3ZTV A;  3DW8 C;  4H2F A;  2O8A A;  2CV9 A;  3EGH A;  3AV0 A;  3D03 A;  4LTY A;  1XZW A;  4ORA A;  3T1I A;  1TCO A;  2HY1 A;  2HYO A;  1U32 A;  3QFK A;  4F0Z A;  2ZBM A;  4HD0 A;  4ZVZ A;  2WDC A;  5J28 A;  3H60 A;  4DT2 A;  4O24 A;  4O4K A;  4MOY A;  3H61 A;  2QJC A;  3CK2 A;  4ORC A;  3H66 A;  5EQV A;  3E7B A;  2NYM C;  2BCD A;  2Z06 A;  1S70 A;  3ZU0 A;  4OR9 A;  1S3N A;  1WAR A;  3H62 B;  1OI8 A;  4H1Y P;  4V0W A;  3FGA C;  3TGH A;  1QHW A;  4G9J A;  4DSY A;  2YEQ A;  2USH A;  4V0X A;  1AUI A;  3QG5 C;  3RL3 A;  4V0V A;  3EGG A;  1S3M A;  1UF3 A;  4LU9 A;  3RQZ A;  1KBP A;  4KKZ A;  4O43 A;  3V4Y A;  2WDD A;  3PSO A;  3GVE A;  3KBP A;  3FLO A;  4H2G A;  2YVT A;  5B8I A;  4I5L C;  2JOG A;  1XM7 A;  1WAO 1;  2IE4 C;  2Q8U A;  1USH A;  1HO5 A;  1V73 A;  1MF8 A;  1II7 A;  1S3L A;  1UTE A;  1NNW A;  2P6B A;  2Z72 A;  3IB8 A;  3IVE A;  2R17 A;  3IB7 A;  4YKE A;  3E0J A;  1S8E A;  5DNY A;  3HVQ A;  4FBK A;  1G5B A;  1Z2W A;  1T70 A;  3C9F A;  4JA9 A;  4Q7F A;  4H1S A;  5GTU A;  1S95 A;  1OID A;  3K7W C;  4MOV A;  1QFC A;  1M63 A;  4XPN A;  3H63 A;  4NZV A;  4FBQ A;  4TUI A;  4ZX2 A;  2BDX A;  2O8G A;  2ZO9 B;  4UWQ A;  3N5U A;  3THN A;  4UT3 A;  4LAC C;  2NYL C;  1IT6 A;  5INB A;  4H2I A;  3LL8 A;  3H69 A;  3P71 C;  2QFR A;  5C1V A;  4M0V A;  4UT2 A;  3AUZ A;  4ORB A;  4TUG A;  2NXF A;  4IYP C;  4I5N C;  3PSN A;  1SU1 A;  1HP1 A;  2DXN A;  2GJU A;  2DFJ A;  1HPU A;  4DHL A;  5F3W A;  1Z2X A;  1W24 A;  3RL5 A;  2QFP A;  1T71 A;  2BQ8 X;  3QFN A;  3JYF A;  4UT3 B;  4JA7 A;  2NPP C;  3H68 A;  4MP0 A;  2AHD A;  3DSC A;  4IL1 A;  2KKN A;  2ZOA A;  4WWL A;  3RL4 A;  2IAE C;  3ICF A;  5JJT A;  4J6O A;  2HYP A;  2A22 A;  3DSD A;  3C5W C; 
#chains in the Genus database with same CATH homology
 5JPE A;  2XMO A;  1JK7 A;  3K7V C;  4O5G A;  3H64 A;  3QFM A;  4FCX A;  4B2O A;  5IOH A;  2WDE A;  1OIE A;  4KBP A;  1FJM A;  2Z1A A;  3QFO A;  5JPF A;  4FBW A;  4H2B A;  5HPE A;  3IVD A;  2IE3 C;  2DXL A;  2WDF A;  3H67 A;  3THO B;  3E7A A;  3ZTV A;  3DW8 C;  4H2F A;  2O8A A;  2CV9 A;  3EGH A;  3AV0 A;  3D03 A;  4LTY A;  1XZW A;  4ORA A;  3T1I A;  1TCO A;  2HY1 A;  2HYO A;  1U32 A;  3QFK A;  4F0Z A;  2ZBM A;  4HD0 A;  4ZVZ A;  2WDC A;  5J28 A;  3H60 A;  4DT2 A;  4O24 A;  4O4K A;  4MOY A;  3H61 A;  2QJC A;  3CK2 A;  4ORC A;  3H66 A;  5EQV A;  3E7B A;  2NYM C;  2BCD A;  2Z06 A;  1S70 A;  3ZU0 A;  4OR9 A;  1S3N A;  1WAR A;  3H62 B;  1OI8 A;  4H1Y P;  4V0W A;  3FGA C;  3TGH A;  1QHW A;  4G9J A;  4DSY A;  2YEQ A;  2USH A;  4V0X A;  1AUI A;  3QG5 C;  3RL3 A;  4V0V A;  3EGG A;  1S3M A;  1UF3 A;  4LU9 A;  3RQZ A;  1KBP A;  4KKZ A;  4O43 A;  3V4Y A;  2WDD A;  3PSO A;  3GVE A;  3KBP A;  3FLO A;  4H2G A;  2YVT A;  5B8I A;  4I5L C;  2JOG A;  1XM7 A;  1WAO 1;  2IE4 C;  2Q8U A;  1USH A;  1HO5 A;  1V73 A;  1MF8 A;  1II7 A;  1S3L A;  1UTE A;  1NNW A;  2P6B A;  2Z72 A;  3IB8 A;  3IVE A;  2R17 A;  3IB7 A;  4YKE A;  3E0J A;  1S8E A;  5DNY A;  3HVQ A;  4FBK A;  1G5B A;  1Z2W A;  1T70 A;  3C9F A;  4JA9 A;  4Q7F A;  4H1S A;  5GTU A;  1S95 A;  1OID A;  3K7W C;  4MOV A;  1QFC A;  1M63 A;  4XPN A;  3H63 A;  4NZV A;  4FBQ A;  4TUI A;  4ZX2 A;  2BDX A;  2O8G A;  2ZO9 B;  4UWQ A;  3N5U A;  3THN A;  4UT3 A;  4LAC C;  2NYL C;  1IT6 A;  5INB A;  4H2I A;  3LL8 A;  3H69 A;  3P71 C;  2QFR A;  5C1V A;  4M0V A;  4UT2 A;  3AUZ A;  4ORB A;  4TUG A;  2NXF A;  4IYP C;  4I5N C;  3PSN A;  1SU1 A;  1HP1 A;  2DXN A;  2GJU A;  2DFJ A;  1HPU A;  4DHL A;  5F3W A;  1Z2X A;  1W24 A;  3RL5 A;  2QFP A;  1T71 A;  2BQ8 X;  3QFN A;  3JYF A;  4UT3 B;  4JA7 A;  2NPP C;  3H68 A;  4MP0 A;  2AHD A;  3DSC A;  4IL1 A;  2KKN A;  2ZOA A;  4WWL A;  3RL4 A;  2IAE C;  3ICF A;  5JJT A;  4J6O A;  2HYP A;  2A22 A;  3DSD A;  3C5W C;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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