2QJCA

Crystal structure of a putative diadenosine tetraphosphatase
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
242
structure length
222
Chain Sequence
YANVVTLPNVTGRVIIVGDIHGCRAQLEDLLRAVSFKQGSDTLVAVGDLVNKGPDSFGVVRLLKRLGAYSVLGNHDAKLLKLVKKLSLAPLAQSIPTDVETYLSQLPHIIRIPAHNVMVAHAGLHPQRPVDRQYEDEVTTMRNLIEKVTLTATEETNDGGKPWASMWRGPETVVFGHDARRGLQEQYKPLAIGLDSRCVYGGRLSAAVFPGGCIISVPGWNG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structural genomics of protein phosphatases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma brucei
molecule keywords Diadenosine tetraphosphatase, putative
total genus 63
structure length 222
sequence length 242
ec nomenclature ec 3.6.1.41: Bis(5'-nucleosyl)-tetraphosphatase (symmetrical).
pdb deposition date 2007-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2qjcA00
3ICFA 3EGGA 2NXFA 2WDDA 3P71C 1G5BA 1W24A 2AHDA 4FBKA 5IOHA 3T1IA 1T70A 4V0XA 4YKEA 3H62B 1S3NA 1S8EA 2WDCA 2IAEC 5J28A 4DT2A 2XMOA 3AUZA 4LTYA 4FBQA 3IVDA 3THOB 3H63A 2WDEA 3QFMA 1UTEA 3KBPA 3TGHA 3N5UA 3DSCA 2HYPA 4MOYA 4O4KA 1Z2WA 1SU1A 4H2GA 4V0VA 4TUIA 2BCDA 4FCXA 4ZVZA 3EGHA 3QFKA 4M0VA 5JJTA 3JYFA 1OIDA 4H2IA 5EQVA 2HY1A 4OR9A 1WAO1 4UWQA 1HPUA 4ORCA 3V4YA 1IT6A 3CK2A 2YVTA 1QFCA 4H2BA 2Z72A 4UT2A 1MF8A 4LACC 2O8GA 3RL3A 2IE4C 3RL4A 2A22A 2QFRA 1QHWA 3H60A 2USHA 3LL8A 1JK7A 1USHA 4FBWA 4H2FA 1FJMA 2Z06A 3K7WC 4B2OA 4HD0A 1NNWA 3DSDA 1T71A 4DHLA 1XM7A 4JA7A 4ORBA 2CV9A 2NPPC 3DW8C 4O24A 4IL1A 3HVQA 2GJUA 1OI8A 5JPEA 2R17A 2O8AA 3PSNA 2KKNA 4KKZA 5DNYA 4IYPC 4Q7FA 2NYMC 4MOVA 1HP1A 1Z2XA 1WARA 3E7AA 3H61A 3PSOA 5JPFA 2Q8UA 4WWLA 4ZX2A 1S3MA 3H66A 3H68A 4LU9A 1OIEA 3RL5A 5GTUA 4MP0A 4UT3B 4DSYA 1S70A 3QG5C 2BQ8X 2P6BA 1KBPA 3QFNA 1S3LA 4UT3A 4H1SA 4O43A 2HYOA 1M63A 4TUGA 1U32A 3IB8A 4G9JA 2Z1AA 5HPEA 2JOGA 3ZU0A 2DFJA 5INBA 1XZWA 3C5WC 3FGAC 1UF3A 2QJCA 4KBPA 4ORAA 4H1YP 3THNA 1S95A 3K7VC 2ZBMA 1TCOA 1II7A 5B8IA 3QFOA 3IB7A 4XPNA 1V73A 3IVEA 4I5LC 3C9FA 1HO5A 2WDFA 3AV0A 3GVEA 4I5NC 3RQZA 5F3WA 3E7BA 5C1VA 2NYLC 3H64A 3H69A 3ZTVA 4F0ZA 4V0WA 2QFPA 1AUIA 2IE3C 3H67A 4NZVA 4J6OA 4JA9A 4O5GA 2BDXA
chains in the Genus database with same CATH superfamily
2YEQA 2DXLA 3ICFA 3EGGA 3D03A 2NXFA 2WDDA 3P71C 1G5BA 1W24A 2AHDA 4FBKA 5IOHA 3T1IA 1T70A 4V0XA 4YKEA 3H62B 1S3NA 1S8EA 2WDCA 2IAEC 5J28A 4DT2A 2XMOA 3AUZA 4LTYA 4FBQA 3IVDA 3THOB 3H63A 2WDEA 3QFMA 1UTEA 3KBPA 3TGHA 3N5UA 3DSCA 2HYPA 4MOYA 4O4KA 1Z2WA 1SU1A 4H2GA 4V0VA 4TUIA 2BCDA 4FCXA 4ZVZA 3EGHA 3QFKA 4M0VA 5JJTA 3JYFA 1OIDA 4H2IA 5EQVA 2HY1A 4OR9A 1WAO1 4UWQA 1HPUA 2ZO9B 4ORCA 3V4YA 1IT6A 3CK2A 2YVTA 1QFCA 4H2BA 2Z72A 4UT2A 1MF8A 4LACC 2O8GA 3RL3A 2IE4C 3RL4A 2A22A 2QFRA 1QHWA 3H60A 2USHA 3LL8A 3E0JA 1JK7A 1USHA 4FBWA 4H2FA 1FJMA 2Z06A 3K7WC 4B2OA 4HD0A 1NNWA 3DSDA 1T71A 4DHLA 1XM7A 4JA7A 4ORBA 2CV9A 2NPPC 3DW8C 4O24A 4IL1A 3HVQA 2GJUA 2ZOAA 1OI8A 5JPEA 2R17A 2O8AA 3PSNA 2KKNA 4KKZA 5DNYA 2DXNA 4IYPC 4Q7FA 2NYMC 4MOVA 1HP1A 1Z2XA 1WARA 3E7AA 3H61A 3PSOA 5JPFA 2Q8UA 4WWLA 4ZX2A 1S3MA 3H66A 3H68A 4LU9A 1OIEA 3RL5A 5GTUA 4MP0A 4UT3B 4DSYA 1S70A 3QG5C 2BQ8X 3FLOA 2P6BA 1KBPA 3QFNA 1S3LA 4UT3A 4H1SA 4O43A 2HYOA 1M63A 4TUGA 1U32A 3IB8A 4G9JA 2Z1AA 5HPEA 2JOGA 3ZU0A 2DFJA 5INBA 1XZWA 3C5WC 3FGAC 1UF3A 2QJCA 4KBPA 4ORAA 4H1YP 3THNA 1S95A 3K7VC 2ZBMA 1TCOA 1II7A 5B8IA 3QFOA 3IB7A 4XPNA 1V73A 3IVEA 4I5LC 3C9FA 1HO5A 2WDFA 3AV0A 3GVEA 4I5NC 3RQZA 5F3WA 3E7BA 5C1VA 2NYLC 3H64A 3H69A 3ZTVA 4F0ZA 4V0WA 2QFPA 1AUIA 2IE3C 3H67A 4NZVA 4J6OA 4JA9A 4O5GA 2BDXA
chains in the Genus database with same CATH topology
2YEQA 2DXLA 3ICFA 3EGGA 3D03A 2NXFA 2WDDA 3P71C 1G5BA 1W24A 2AHDA 4FBKA 5IOHA 3T1IA 1T70A 4V0XA 4YKEA 3H62B 1S3NA 1S8EA 2WDCA 2IAEC 5J28A 4DT2A 2XMOA 3AUZA 4LTYA 4FBQA 3IVDA 3THOB 3H63A 2WDEA 3QFMA 1UTEA 3KBPA 3TGHA 3N5UA 3DSCA 2HYPA 4MOYA 4O4KA 1Z2WA 1SU1A 4H2GA 4V0VA 4TUIA 2BCDA 4FCXA 4ZVZA 3EGHA 3QFKA 4M0VA 5JJTA 3JYFA 1OIDA 4H2IA 5EQVA 2HY1A 4OR9A 1WAO1 4UWQA 1HPUA 2ZO9B 4ORCA 3V4YA 1IT6A 3CK2A 2YVTA 1QFCA 4H2BA 2Z72A 4UT2A 1MF8A 4LACC 2O8GA 3RL3A 2IE4C 3RL4A 2A22A 2QFRA 1QHWA 3H60A 2USHA 3LL8A 3E0JA 1JK7A 1USHA 4FBWA 4H2FA 1FJMA 2Z06A 3K7WC 4B2OA 4HD0A 1NNWA 3DSDA 1T71A 4DHLA 1XM7A 4JA7A 4ORBA 2CV9A 2NPPC 3DW8C 4O24A 4IL1A 3HVQA 2GJUA 2ZOAA 1OI8A 5JPEA 2R17A 2O8AA 3PSNA 2KKNA 4KKZA 5DNYA 2DXNA 4IYPC 4Q7FA 2NYMC 4MOVA 1HP1A 1Z2XA 1WARA 3E7AA 3H61A 3PSOA 5JPFA 2Q8UA 4WWLA 4ZX2A 1S3MA 3H66A 3H68A 4LU9A 1OIEA 3RL5A 5GTUA 4MP0A 4UT3B 4DSYA 1S70A 3QG5C 2BQ8X 3FLOA 2P6BA 1KBPA 3QFNA 1S3LA 4UT3A 4H1SA 4O43A 2HYOA 1M63A 4TUGA 1U32A 3IB8A 4G9JA 2Z1AA 5HPEA 2JOGA 3ZU0A 2DFJA 5INBA 1XZWA 3C5WC 3FGAC 1UF3A 2QJCA 4KBPA 4ORAA 4H1YP 3THNA 1S95A 3K7VC 2ZBMA 1TCOA 1II7A 5B8IA 3QFOA 3IB7A 4XPNA 1V73A 3IVEA 4I5LC 3C9FA 1HO5A 2WDFA 3AV0A 3GVEA 4I5NC 3RQZA 5F3WA 3E7BA 5C1VA 2NYLC 3H64A 3H69A 3ZTVA 4F0ZA 4V0WA 2QFPA 1AUIA 2IE3C 3H67A 4NZVA 4J6OA 4JA9A 4O5GA 2BDXA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3ICF A;  3EGG A;  2NXF A;  2WDD A;  3P71 C;  1G5B A;  1W24 A;  2AHD A;  4FBK A;  5IOH A;  3T1I A;  1T70 A;  4V0X A;  4YKE A;  3H62 B;  1S3N A;  1S8E A;  2WDC A;  2IAE C;  5J28 A;  4DT2 A;  2XMO A;  3AUZ A;  4LTY A;  4FBQ A;  3IVD A;  3THO B;  3H63 A;  2WDE A;  3QFM A;  1UTE A;  3KBP A;  3TGH A;  3N5U A;  3DSC A;  2HYP A;  4MOY A;  4O4K A;  1Z2W A;  1SU1 A;  4H2G A;  4V0V A;  4TUI A;  2BCD A;  4FCX A;  4ZVZ A;  3EGH A;  3QFK A;  4M0V A;  5JJT A;  3JYF A;  1OID A;  4H2I A;  5EQV A;  2HY1 A;  4OR9 A;  1WAO 1;  4UWQ A;  1HPU A;  4ORC A;  3V4Y A;  1IT6 A;  3CK2 A;  2YVT A;  1QFC A;  4H2B A;  2Z72 A;  4UT2 A;  1MF8 A;  4LAC C;  2O8G A;  3RL3 A;  2IE4 C;  3RL4 A;  2A22 A;  2QFR A;  1QHW A;  3H60 A;  2USH A;  3LL8 A;  1JK7 A;  1USH A;  4FBW A;  4H2F A;  1FJM A;  2Z06 A;  3K7W C;  4B2O A;  4HD0 A;  1NNW A;  3DSD A;  1T71 A;  4DHL A;  1XM7 A;  4JA7 A;  4ORB A;  2CV9 A;  2NPP C;  3DW8 C;  4O24 A;  4IL1 A;  3HVQ A;  2GJU A;  1OI8 A;  5JPE A;  2R17 A;  2O8A A;  3PSN A;  2KKN A;  4KKZ A;  5DNY A;  4IYP C;  4Q7F A;  2NYM C;  4MOV A;  1HP1 A;  1Z2X A;  1WAR A;  3E7A A;  3H61 A;  3PSO A;  5JPF A;  2Q8U A;  4WWL A;  4ZX2 A;  1S3M A;  3H66 A;  3H68 A;  4LU9 A;  1OIE A;  3RL5 A;  5GTU A;  4MP0 A;  4UT3 B;  4DSY A;  1S70 A;  3QG5 C;  2BQ8 X;  2P6B A;  1KBP A;  3QFN A;  1S3L A;  4UT3 A;  4H1S A;  4O43 A;  2HYO A;  1M63 A;  4TUG A;  1U32 A;  3IB8 A;  4G9J A;  2Z1A A;  5HPE A;  2JOG A;  3ZU0 A;  2DFJ A;  5INB A;  1XZW A;  3C5W C;  3FGA C;  1UF3 A;  2QJC A;  4KBP A;  4ORA A;  4H1Y P;  3THN A;  1S95 A;  3K7V C;  2ZBM A;  1TCO A;  1II7 A;  5B8I A;  3QFO A;  3IB7 A;  4XPN A;  1V73 A;  3IVE A;  4I5L C;  3C9F A;  1HO5 A;  2WDF A;  3AV0 A;  3GVE A;  4I5N C;  3RQZ A;  5F3W A;  3E7B A;  5C1V A;  2NYL C;  3H64 A;  3H69 A;  3ZTV A;  4F0Z A;  4V0W A;  2QFP A;  1AUI A;  2IE3 C;  3H67 A;  4NZV A;  4J6O A;  4JA9 A;  4O5G A;  2BDX A; 
#chains in the Genus database with same CATH topology
 2YEQ A;  2DXL A;  3ICF A;  3EGG A;  3D03 A;  2NXF A;  2WDD A;  3P71 C;  1G5B A;  1W24 A;  2AHD A;  4FBK A;  5IOH A;  3T1I A;  1T70 A;  4V0X A;  4YKE A;  3H62 B;  1S3N A;  1S8E A;  2WDC A;  2IAE C;  5J28 A;  4DT2 A;  2XMO A;  3AUZ A;  4LTY A;  4FBQ A;  3IVD A;  3THO B;  3H63 A;  2WDE A;  3QFM A;  1UTE A;  3KBP A;  3TGH A;  3N5U A;  3DSC A;  2HYP A;  4MOY A;  4O4K A;  1Z2W A;  1SU1 A;  4H2G A;  4V0V A;  4TUI A;  2BCD A;  4FCX A;  4ZVZ A;  3EGH A;  3QFK A;  4M0V A;  5JJT A;  3JYF A;  1OID A;  4H2I A;  5EQV A;  2HY1 A;  4OR9 A;  1WAO 1;  4UWQ A;  1HPU A;  2ZO9 B;  4ORC A;  3V4Y A;  1IT6 A;  3CK2 A;  2YVT A;  1QFC A;  4H2B A;  2Z72 A;  4UT2 A;  1MF8 A;  4LAC C;  2O8G A;  3RL3 A;  2IE4 C;  3RL4 A;  2A22 A;  2QFR A;  1QHW A;  3H60 A;  2USH A;  3LL8 A;  3E0J A;  1JK7 A;  1USH A;  4FBW A;  4H2F A;  1FJM A;  2Z06 A;  3K7W C;  4B2O A;  4HD0 A;  1NNW A;  3DSD A;  1T71 A;  4DHL A;  1XM7 A;  4JA7 A;  4ORB A;  2CV9 A;  2NPP C;  3DW8 C;  4O24 A;  4IL1 A;  3HVQ A;  2GJU A;  2ZOA A;  1OI8 A;  5JPE A;  2R17 A;  2O8A A;  3PSN A;  2KKN A;  4KKZ A;  5DNY A;  2DXN A;  4IYP C;  4Q7F A;  2NYM C;  4MOV A;  1HP1 A;  1Z2X A;  1WAR A;  3E7A A;  3H61 A;  3PSO A;  5JPF A;  2Q8U A;  4WWL A;  4ZX2 A;  1S3M A;  3H66 A;  3H68 A;  4LU9 A;  1OIE A;  3RL5 A;  5GTU A;  4MP0 A;  4UT3 B;  4DSY A;  1S70 A;  3QG5 C;  2BQ8 X;  3FLO A;  2P6B A;  1KBP A;  3QFN A;  1S3L A;  4UT3 A;  4H1S A;  4O43 A;  2HYO A;  1M63 A;  4TUG A;  1U32 A;  3IB8 A;  4G9J A;  2Z1A A;  5HPE A;  2JOG A;  3ZU0 A;  2DFJ A;  5INB A;  1XZW A;  3C5W C;  3FGA C;  1UF3 A;  2QJC A;  4KBP A;  4ORA A;  4H1Y P;  3THN A;  1S95 A;  3K7V C;  2ZBM A;  1TCO A;  1II7 A;  5B8I A;  3QFO A;  3IB7 A;  4XPN A;  1V73 A;  3IVE A;  4I5L C;  3C9F A;  1HO5 A;  2WDF A;  3AV0 A;  3GVE A;  4I5N C;  3RQZ A;  5F3W A;  3E7B A;  5C1V A;  2NYL C;  3H64 A;  3H69 A;  3ZTV A;  4F0Z A;  4V0W A;  2QFP A;  1AUI A;  2IE3 C;  3H67 A;  4NZV A;  4J6O A;  4JA9 A;  4O5G A;  2BDX A; 
#chains in the Genus database with same CATH homology
 2YEQ A;  2DXL A;  3ICF A;  3EGG A;  3D03 A;  2NXF A;  2WDD A;  3P71 C;  1G5B A;  1W24 A;  2AHD A;  4FBK A;  5IOH A;  3T1I A;  1T70 A;  4V0X A;  4YKE A;  3H62 B;  1S3N A;  1S8E A;  2WDC A;  2IAE C;  5J28 A;  4DT2 A;  2XMO A;  3AUZ A;  4LTY A;  4FBQ A;  3IVD A;  3THO B;  3H63 A;  2WDE A;  3QFM A;  1UTE A;  3KBP A;  3TGH A;  3N5U A;  3DSC A;  2HYP A;  4MOY A;  4O4K A;  1Z2W A;  1SU1 A;  4H2G A;  4V0V A;  4TUI A;  2BCD A;  4FCX A;  4ZVZ A;  3EGH A;  3QFK A;  4M0V A;  5JJT A;  3JYF A;  1OID A;  4H2I A;  5EQV A;  2HY1 A;  4OR9 A;  1WAO 1;  4UWQ A;  1HPU A;  2ZO9 B;  4ORC A;  3V4Y A;  1IT6 A;  3CK2 A;  2YVT A;  1QFC A;  4H2B A;  2Z72 A;  4UT2 A;  1MF8 A;  4LAC C;  2O8G A;  3RL3 A;  2IE4 C;  3RL4 A;  2A22 A;  2QFR A;  1QHW A;  3H60 A;  2USH A;  3LL8 A;  3E0J A;  1JK7 A;  1USH A;  4FBW A;  4H2F A;  1FJM A;  2Z06 A;  3K7W C;  4B2O A;  4HD0 A;  1NNW A;  3DSD A;  1T71 A;  4DHL A;  1XM7 A;  4JA7 A;  4ORB A;  2CV9 A;  2NPP C;  3DW8 C;  4O24 A;  4IL1 A;  3HVQ A;  2GJU A;  2ZOA A;  1OI8 A;  5JPE A;  2R17 A;  2O8A A;  3PSN A;  2KKN A;  4KKZ A;  5DNY A;  2DXN A;  4IYP C;  4Q7F A;  2NYM C;  4MOV A;  1HP1 A;  1Z2X A;  1WAR A;  3E7A A;  3H61 A;  3PSO A;  5JPF A;  2Q8U A;  4WWL A;  4ZX2 A;  1S3M A;  3H66 A;  3H68 A;  4LU9 A;  1OIE A;  3RL5 A;  5GTU A;  4MP0 A;  4UT3 B;  4DSY A;  1S70 A;  3QG5 C;  2BQ8 X;  3FLO A;  2P6B A;  1KBP A;  3QFN A;  1S3L A;  4UT3 A;  4H1S A;  4O43 A;  2HYO A;  1M63 A;  4TUG A;  1U32 A;  3IB8 A;  4G9J A;  2Z1A A;  5HPE A;  2JOG A;  3ZU0 A;  2DFJ A;  5INB A;  1XZW A;  3C5W C;  3FGA C;  1UF3 A;  2QJC A;  4KBP A;  4ORA A;  4H1Y P;  3THN A;  1S95 A;  3K7V C;  2ZBM A;  1TCO A;  1II7 A;  5B8I A;  3QFO A;  3IB7 A;  4XPN A;  1V73 A;  3IVE A;  4I5L C;  3C9F A;  1HO5 A;  2WDF A;  3AV0 A;  3GVE A;  4I5N C;  3RQZ A;  5F3W A;  3E7B A;  5C1V A;  2NYL C;  3H64 A;  3H69 A;  3ZTV A;  4F0Z A;  4V0W A;  2QFP A;  1AUI A;  2IE3 C;  3H67 A;  4NZV A;  4J6O A;  4JA9 A;  4O5G A;  2BDX A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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