2QJCA

Crystal structure of a putative diadenosine tetraphosphatase
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
242
structure length
222
Chain Sequence
YANVVTLPNVTGRVIIVGDIHGCRAQLEDLLRAVSFKQGSDTLVAVGDLVNKGPDSFGVVRLLKRLGAYSVLGNHDAKLLKLVKKLSLAPLAQSIPTDVETYLSQLPHIIRIPAHNVMVAHAGLHPQRPVDRQYEDEVTTMRNLIEKVTLTATEETNDGGKPWASMWRGPETVVFGHDARRGLQEQYKPLAIGLDSRCVYGGRLSAAVFPGGCIISVPGWNG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structural genomics of protein phosphatases.
pubmed doi rcsb
molecule keywords Diadenosine tetraphosphatase, putative
molecule tags Hydrolase
source organism Trypanosoma brucei
total genus 63
structure length 222
sequence length 242
ec nomenclature ec 3.6.1.41: Bis(5'-nucleosyl)-tetraphosphatase (symmetrical).
pdb deposition date 2007-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2qjcA00
2IE3C 3E7BA 2BCDA 5JJTA 4NZVA 1U32A 3H66A 1TCOA 1HPUA 2HYPA 4O43A 4MOVA 2BQ8X 2WDEA 1KBPA 5F3WA 1QFCA 4MP0A 1IT6A 4WWLA 3C5WC 4HD0A 1OIEA 3PSNA 2USHA 1V73A 3EGGA 4O4KA 3DSCA 1SU1A 3H67A 1HP1A 2P6BA 2QFRA 1S3LA 1T70A 3HVQA 2NPPC 1MF8A 3EGHA 4I5NC 1HO5A 3CK2A 3N5UA 3RL4A 3PSOA 3QFKA 3ICFA 2IE4C 2BDXA 3KBPA 4LU9A 4YKEA 5C1VA 4O5GA 4DT2A 4UT3B 1XZWA 2NXFA 2ZBMA 2HY1A 4LTYA 3QFOA 3GVEA 2O8AA 5B8IA 3E7AA 3QFMA 4H2BA 3LL8A 5INBA 1S3NA 4V0VA 3K7VC 4V0XA 2GJUA 1OI8A 1W24A 4FBQA 1QHWA 3IVEA 4V0WA 3H64A 1Z2WA 4ZVZA 4B2OA 2Q8UA 2IAEC 1FJMA 4MOYA 4H1SA 1AUIA 3RL5A 3QG5C 3H68A 3AV0A 4JA9A 2WDCA 1WAO1 1WARA 3JYFA 3IVDA 4FCXA 4TUGA 3QFNA 2Z1AA 2Z72A 2DFJA 3TGHA 4LACC 4F0ZA 2A22A 3IB8A 4OR9A 4UWQA 3DW8C 4KKZA 5JPFA 5J28A 1UF3A 2QJCA 2CV9A 1S8EA 3H61A 4IL1A 3V4YA 5IOHA 2WDFA 2NYLC 3RL3A 3H62B 4JA7A 1S3MA 3C9FA 4XPNA 3FGAC 4G9JA 1T71A 3THOB 4J6OA 3P71C 5EQVA 1JK7A 4ORAA 4DHLA 2HYOA 1II7A 4DSYA 2O8GA 3DSDA 3ZU0A 3IB7A 5HPEA 5DNYA 4UT3A 3THNA 1G5BA 1S95A 5JPEA 1OIDA 4M0VA 4IYPC 2Z06A 4H2FA 2QFPA 4FBKA 4O24A 2JOGA 3H60A 3H63A 4TUIA 3AUZA 4KBPA 4H1YP 1XM7A 4H2IA 4ORBA 5GTUA 1NNWA 2AHDA 1M63A 2KKNA 2R17A 3H69A 4ZX2A 1UTEA 4H2GA 4ORCA 1S70A 2NYMC 4UT2A 4FBWA 3T1IA 1Z2XA 4I5LC 3RQZA 3ZTVA 2YVTA 4Q7FA 2WDDA 2XMOA 3K7WC 1USHA
chains in the Genus database with same CATH superfamily
2IE3C 3E7BA 2BCDA 5JJTA 4NZVA 1U32A 3H66A 1TCOA 1HPUA 2HYPA 4O43A 4MOVA 2BQ8X 2DXNA 2WDEA 1KBPA 5F3WA 1QFCA 4MP0A 1IT6A 4WWLA 3C5WC 4HD0A 2YEQA 1OIEA 3PSNA 2USHA 1V73A 3EGGA 3D03A 4O4KA 3DSCA 1SU1A 3H67A 2ZO9B 1HP1A 2P6BA 2QFRA 1S3LA 1T70A 3HVQA 2NPPC 1MF8A 3EGHA 4I5NC 1HO5A 3CK2A 3N5UA 3RL4A 3PSOA 3QFKA 3ICFA 2IE4C 2BDXA 3KBPA 4LU9A 4YKEA 5C1VA 4O5GA 4DT2A 4UT3B 1XZWA 2NXFA 2ZBMA 2HY1A 4LTYA 3QFOA 3GVEA 2O8AA 5B8IA 3E7AA 3QFMA 4H2BA 3LL8A 5INBA 1S3NA 2DXLA 4V0VA 3K7VC 4V0XA 2GJUA 1OI8A 1W24A 4FBQA 1QHWA 3IVEA 4V0WA 3H64A 1Z2WA 4ZVZA 4B2OA 2ZOAA 2Q8UA 2IAEC 1FJMA 4MOYA 4H1SA 1AUIA 3RL5A 3QG5C 3H68A 3AV0A 4JA9A 2WDCA 1WAO1 1WARA 3JYFA 3IVDA 4FCXA 4TUGA 3QFNA 2Z1AA 2Z72A 2DFJA 3TGHA 4LACC 4F0ZA 2A22A 3IB8A 4OR9A 4UWQA 3DW8C 4KKZA 5JPFA 5J28A 1UF3A 2QJCA 2CV9A 1S8EA 3H61A 4IL1A 3V4YA 5IOHA 2WDFA 2NYLC 3RL3A 3H62B 4JA7A 1S3MA 3C9FA 4XPNA 3FGAC 4G9JA 1T71A 3THOB 4J6OA 3P71C 5EQVA 1JK7A 4ORAA 4DHLA 2HYOA 1II7A 4DSYA 2O8GA 3DSDA 3ZU0A 3IB7A 5HPEA 5DNYA 4UT3A 3THNA 1G5BA 1S95A 5JPEA 1OIDA 3E0JA 4M0VA 4IYPC 2Z06A 4H2FA 2QFPA 4FBKA 4O24A 2JOGA 3H60A 3H63A 4TUIA 3AUZA 4KBPA 4H1YP 1XM7A 4H2IA 4ORBA 3FLOA 1NNWA 5GTUA 2AHDA 1M63A 2KKNA 2R17A 3H69A 4ZX2A 1UTEA 4H2GA 4ORCA 1S70A 2NYMC 4UT2A 4FBWA 3T1IA 1Z2XA 4I5LC 3RQZA 3ZTVA 2YVTA 4Q7FA 2WDDA 2XMOA 3K7WC 1USHA
chains in the Genus database with same CATH topology
2IE3C 3E7BA 2BCDA 5JJTA 4NZVA 1U32A 3H66A 1TCOA 1HPUA 2HYPA 4O43A 4MOVA 2BQ8X 2DXNA 2WDEA 1KBPA 5F3WA 1QFCA 4MP0A 1IT6A 4WWLA 3C5WC 4HD0A 2YEQA 1OIEA 3PSNA 2USHA 1V73A 3EGGA 3D03A 4O4KA 3DSCA 1SU1A 3H67A 2ZO9B 1HP1A 2P6BA 2QFRA 1S3LA 1T70A 3HVQA 2NPPC 1MF8A 3EGHA 4I5NC 1HO5A 3CK2A 3N5UA 3RL4A 3PSOA 3QFKA 3ICFA 2IE4C 2BDXA 3KBPA 4LU9A 4YKEA 5C1VA 4O5GA 4DT2A 4UT3B 1XZWA 2NXFA 2ZBMA 2HY1A 4LTYA 3QFOA 3GVEA 2O8AA 5B8IA 3E7AA 3QFMA 4H2BA 3LL8A 5INBA 1S3NA 2DXLA 4V0VA 3K7VC 4V0XA 2GJUA 1OI8A 1W24A 4FBQA 1QHWA 3IVEA 4V0WA 3H64A 1Z2WA 4ZVZA 4B2OA 2ZOAA 2Q8UA 2IAEC 1FJMA 4MOYA 4H1SA 1AUIA 3RL5A 3QG5C 3H68A 3AV0A 4JA9A 2WDCA 1WAO1 1WARA 3JYFA 3IVDA 4FCXA 4TUGA 3QFNA 2Z1AA 2Z72A 2DFJA 3TGHA 4LACC 4F0ZA 2A22A 3IB8A 4OR9A 4UWQA 3DW8C 4KKZA 5JPFA 5J28A 1UF3A 2QJCA 2CV9A 1S8EA 3H61A 4IL1A 3V4YA 5IOHA 2WDFA 2NYLC 3RL3A 3H62B 4JA7A 1S3MA 3C9FA 4XPNA 3FGAC 4G9JA 1T71A 3THOB 4J6OA 3P71C 5EQVA 1JK7A 4ORAA 4DHLA 2HYOA 1II7A 4DSYA 2O8GA 3DSDA 3ZU0A 3IB7A 5HPEA 5DNYA 4UT3A 3THNA 1G5BA 1S95A 5JPEA 1OIDA 3E0JA 4M0VA 4IYPC 2Z06A 4H2FA 2QFPA 4FBKA 4O24A 2JOGA 3H60A 3H63A 4TUIA 3AUZA 4KBPA 4H1YP 1XM7A 4H2IA 4ORBA 3FLOA 1NNWA 5GTUA 2AHDA 1M63A 2KKNA 2R17A 3H69A 4ZX2A 1UTEA 4H2GA 4ORCA 1S70A 2NYMC 4UT2A 4FBWA 3T1IA 1Z2XA 4I5LC 3RQZA 3ZTVA 2YVTA 4Q7FA 2WDDA 2XMOA 3K7WC 1USHA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2IE3 C;  3E7B A;  2BCD A;  5JJT A;  4NZV A;  1U32 A;  3H66 A;  1TCO A;  1HPU A;  2HYP A;  4O43 A;  4MOV A;  2BQ8 X;  2WDE A;  1KBP A;  5F3W A;  1QFC A;  4MP0 A;  1IT6 A;  4WWL A;  3C5W C;  4HD0 A;  1OIE A;  3PSN A;  2USH A;  1V73 A;  3EGG A;  4O4K A;  3DSC A;  1SU1 A;  3H67 A;  1HP1 A;  2P6B A;  2QFR A;  1S3L A;  1T70 A;  3HVQ A;  2NPP C;  1MF8 A;  3EGH A;  4I5N C;  1HO5 A;  3CK2 A;  3N5U A;  3RL4 A;  3PSO A;  3QFK A;  3ICF A;  2IE4 C;  2BDX A;  3KBP A;  4LU9 A;  4YKE A;  5C1V A;  4O5G A;  4DT2 A;  4UT3 B;  1XZW A;  2NXF A;  2ZBM A;  2HY1 A;  4LTY A;  3QFO A;  3GVE A;  2O8A A;  5B8I A;  3E7A A;  3QFM A;  4H2B A;  3LL8 A;  5INB A;  1S3N A;  4V0V A;  3K7V C;  4V0X A;  2GJU A;  1OI8 A;  1W24 A;  4FBQ A;  1QHW A;  3IVE A;  4V0W A;  3H64 A;  1Z2W A;  4ZVZ A;  4B2O A;  2Q8U A;  2IAE C;  1FJM A;  4MOY A;  4H1S A;  1AUI A;  3RL5 A;  3QG5 C;  3H68 A;  3AV0 A;  4JA9 A;  2WDC A;  1WAO 1;  1WAR A;  3JYF A;  3IVD A;  4FCX A;  4TUG A;  3QFN A;  2Z1A A;  2Z72 A;  2DFJ A;  3TGH A;  4LAC C;  4F0Z A;  2A22 A;  3IB8 A;  4OR9 A;  4UWQ A;  3DW8 C;  4KKZ A;  5JPF A;  5J28 A;  1UF3 A;  2QJC A;  2CV9 A;  1S8E A;  3H61 A;  4IL1 A;  3V4Y A;  5IOH A;  2WDF A;  2NYL C;  3RL3 A;  3H62 B;  4JA7 A;  1S3M A;  3C9F A;  4XPN A;  3FGA C;  4G9J A;  1T71 A;  3THO B;  4J6O A;  3P71 C;  5EQV A;  1JK7 A;  4ORA A;  4DHL A;  2HYO A;  1II7 A;  4DSY A;  2O8G A;  3DSD A;  3ZU0 A;  3IB7 A;  5HPE A;  5DNY A;  4UT3 A;  3THN A;  1G5B A;  1S95 A;  5JPE A;  1OID A;  4M0V A;  4IYP C;  2Z06 A;  4H2F A;  2QFP A;  4FBK A;  4O24 A;  2JOG A;  3H60 A;  3H63 A;  4TUI A;  3AUZ A;  4KBP A;  4H1Y P;  1XM7 A;  4H2I A;  4ORB A;  5GTU A;  1NNW A;  2AHD A;  1M63 A;  2KKN A;  2R17 A;  3H69 A;  4ZX2 A;  1UTE A;  4H2G A;  4ORC A;  1S70 A;  2NYM C;  4UT2 A;  4FBW A;  3T1I A;  1Z2X A;  4I5L C;  3RQZ A;  3ZTV A;  2YVT A;  4Q7F A;  2WDD A;  2XMO A;  3K7W C;  1USH A; 
#chains in the Genus database with same CATH topology
 2IE3 C;  3E7B A;  2BCD A;  5JJT A;  4NZV A;  1U32 A;  3H66 A;  1TCO A;  1HPU A;  2HYP A;  4O43 A;  4MOV A;  2BQ8 X;  2DXN A;  2WDE A;  1KBP A;  5F3W A;  1QFC A;  4MP0 A;  1IT6 A;  4WWL A;  3C5W C;  4HD0 A;  2YEQ A;  1OIE A;  3PSN A;  2USH A;  1V73 A;  3EGG A;  3D03 A;  4O4K A;  3DSC A;  1SU1 A;  3H67 A;  2ZO9 B;  1HP1 A;  2P6B A;  2QFR A;  1S3L A;  1T70 A;  3HVQ A;  2NPP C;  1MF8 A;  3EGH A;  4I5N C;  1HO5 A;  3CK2 A;  3N5U A;  3RL4 A;  3PSO A;  3QFK A;  3ICF A;  2IE4 C;  2BDX A;  3KBP A;  4LU9 A;  4YKE A;  5C1V A;  4O5G A;  4DT2 A;  4UT3 B;  1XZW A;  2NXF A;  2ZBM A;  2HY1 A;  4LTY A;  3QFO A;  3GVE A;  2O8A A;  5B8I A;  3E7A A;  3QFM A;  4H2B A;  3LL8 A;  5INB A;  1S3N A;  2DXL A;  4V0V A;  3K7V C;  4V0X A;  2GJU A;  1OI8 A;  1W24 A;  4FBQ A;  1QHW A;  3IVE A;  4V0W A;  3H64 A;  1Z2W A;  4ZVZ A;  4B2O A;  2ZOA A;  2Q8U A;  2IAE C;  1FJM A;  4MOY A;  4H1S A;  1AUI A;  3RL5 A;  3QG5 C;  3H68 A;  3AV0 A;  4JA9 A;  2WDC A;  1WAO 1;  1WAR A;  3JYF A;  3IVD A;  4FCX A;  4TUG A;  3QFN A;  2Z1A A;  2Z72 A;  2DFJ A;  3TGH A;  4LAC C;  4F0Z A;  2A22 A;  3IB8 A;  4OR9 A;  4UWQ A;  3DW8 C;  4KKZ A;  5JPF A;  5J28 A;  1UF3 A;  2QJC A;  2CV9 A;  1S8E A;  3H61 A;  4IL1 A;  3V4Y A;  5IOH A;  2WDF A;  2NYL C;  3RL3 A;  3H62 B;  4JA7 A;  1S3M A;  3C9F A;  4XPN A;  3FGA C;  4G9J A;  1T71 A;  3THO B;  4J6O A;  3P71 C;  5EQV A;  1JK7 A;  4ORA A;  4DHL A;  2HYO A;  1II7 A;  4DSY A;  2O8G A;  3DSD A;  3ZU0 A;  3IB7 A;  5HPE A;  5DNY A;  4UT3 A;  3THN A;  1G5B A;  1S95 A;  5JPE A;  1OID A;  3E0J A;  4M0V A;  4IYP C;  2Z06 A;  4H2F A;  2QFP A;  4FBK A;  4O24 A;  2JOG A;  3H60 A;  3H63 A;  4TUI A;  3AUZ A;  4KBP A;  4H1Y P;  1XM7 A;  4H2I A;  4ORB A;  3FLO A;  1NNW A;  5GTU A;  2AHD A;  1M63 A;  2KKN A;  2R17 A;  3H69 A;  4ZX2 A;  1UTE A;  4H2G A;  4ORC A;  1S70 A;  2NYM C;  4UT2 A;  4FBW A;  3T1I A;  1Z2X A;  4I5L C;  3RQZ A;  3ZTV A;  2YVT A;  4Q7F A;  2WDD A;  2XMO A;  3K7W C;  1USH A; 
#chains in the Genus database with same CATH homology
 2IE3 C;  3E7B A;  2BCD A;  5JJT A;  4NZV A;  1U32 A;  3H66 A;  1TCO A;  1HPU A;  2HYP A;  4O43 A;  4MOV A;  2BQ8 X;  2DXN A;  2WDE A;  1KBP A;  5F3W A;  1QFC A;  4MP0 A;  1IT6 A;  4WWL A;  3C5W C;  4HD0 A;  2YEQ A;  1OIE A;  3PSN A;  2USH A;  1V73 A;  3EGG A;  3D03 A;  4O4K A;  3DSC A;  1SU1 A;  3H67 A;  2ZO9 B;  1HP1 A;  2P6B A;  2QFR A;  1S3L A;  1T70 A;  3HVQ A;  2NPP C;  1MF8 A;  3EGH A;  4I5N C;  1HO5 A;  3CK2 A;  3N5U A;  3RL4 A;  3PSO A;  3QFK A;  3ICF A;  2IE4 C;  2BDX A;  3KBP A;  4LU9 A;  4YKE A;  5C1V A;  4O5G A;  4DT2 A;  4UT3 B;  1XZW A;  2NXF A;  2ZBM A;  2HY1 A;  4LTY A;  3QFO A;  3GVE A;  2O8A A;  5B8I A;  3E7A A;  3QFM A;  4H2B A;  3LL8 A;  5INB A;  1S3N A;  2DXL A;  4V0V A;  3K7V C;  4V0X A;  2GJU A;  1OI8 A;  1W24 A;  4FBQ A;  1QHW A;  3IVE A;  4V0W A;  3H64 A;  1Z2W A;  4ZVZ A;  4B2O A;  2ZOA A;  2Q8U A;  2IAE C;  1FJM A;  4MOY A;  4H1S A;  1AUI A;  3RL5 A;  3QG5 C;  3H68 A;  3AV0 A;  4JA9 A;  2WDC A;  1WAO 1;  1WAR A;  3JYF A;  3IVD A;  4FCX A;  4TUG A;  3QFN A;  2Z1A A;  2Z72 A;  2DFJ A;  3TGH A;  4LAC C;  4F0Z A;  2A22 A;  3IB8 A;  4OR9 A;  4UWQ A;  3DW8 C;  4KKZ A;  5JPF A;  5J28 A;  1UF3 A;  2QJC A;  2CV9 A;  1S8E A;  3H61 A;  4IL1 A;  3V4Y A;  5IOH A;  2WDF A;  2NYL C;  3RL3 A;  3H62 B;  4JA7 A;  1S3M A;  3C9F A;  4XPN A;  3FGA C;  4G9J A;  1T71 A;  3THO B;  4J6O A;  3P71 C;  5EQV A;  1JK7 A;  4ORA A;  4DHL A;  2HYO A;  1II7 A;  4DSY A;  2O8G A;  3DSD A;  3ZU0 A;  3IB7 A;  5HPE A;  5DNY A;  4UT3 A;  3THN A;  1G5B A;  1S95 A;  5JPE A;  1OID A;  3E0J A;  4M0V A;  4IYP C;  2Z06 A;  4H2F A;  2QFP A;  4FBK A;  4O24 A;  2JOG A;  3H60 A;  3H63 A;  4TUI A;  3AUZ A;  4KBP A;  4H1Y P;  1XM7 A;  4H2I A;  4ORB A;  3FLO A;  1NNW A;  5GTU A;  2AHD A;  1M63 A;  2KKN A;  2R17 A;  3H69 A;  4ZX2 A;  1UTE A;  4H2G A;  4ORC A;  1S70 A;  2NYM C;  4UT2 A;  4FBW A;  3T1I A;  1Z2X A;  4I5L C;  3RQZ A;  3ZTV A;  2YVT A;  4Q7F A;  2WDD A;  2XMO A;  3K7W C;  1USH A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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