2R7ZL

Cisplatin lesion containing rna polymerase ii elongation complex
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription/dna-rna hybrid
publication title Mechanism of transcriptional stalling at cisplatin-damaged DNA.
pubmed doi rcsb
molecule keywords 5'-D(*TP*AP*CP*TP*TP*GUP*CP*CP*CP*TP*CP*CP*TP*CP*AP*T)-3'
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2007-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2r7zL00
4BBRL 3GTKL 5M3ML 3HOVL 2WAQP 4A93L 2NVYL 1TWCL 3HOUL 3M4OL 3H0GL 3PO3L 4AYBP 2E2HL 3S15L 4A3EL 5IYCL 3I4NL 2JA6L 3GTJL 4C2M1 2R92L 5C44L 5C4XL 2E2JL 4C3HL 3GTGL 2VUML 4BY1L 4A3FL 2YU9L 3GTQL 2NVXL 3S1QL 3S16L 2Y0SP 4A3GL 4C3IL 2R7ZL 4A3CL 5FLML 1I3QL 2E2IL 3HOXL 3S1RL 5M5YL 3S17L 3FKIL 1I50L 4Y7NL 5M3FL 5C3EL 3HKZP 1I6HL 3S2HL 3RZOL 2R93L 2NVQL 5C4JL 2PMZP 4A3BL 4X6AL 1WCML 3GTOL 3PO2L 2JA7L 1TWGL 1Y1WL 2NVTL 3H3VM 2B63L 3K7AL 3S2DL 2JA5L 5M5XL 4C3JL 4BY7L 3GTML 4BXXL 3RZDL 3HOZL 3I4ML 4A3IL 1TWAL 1Y1VL 3HOYL 2WB1P 4Y52L 1TWHL 4BBSL 5IP7L 4A3LL 1K83L 1TWFL 3S1NL 3GTPL 2JA8L 3CQZL 5IYBL 4QIWP 4A3ML 5M5WL 5FJ8L 1SFOL 3M3YL 4A3KL 3GTLL 3HOWL 1R9TL 3S14L 4A3DL 4A3JL 5IYDL 3S1ML 5IP9L
chains in the Genus database with same CATH superfamily
3FDJA 3LWPB 2C6AA 2XJPA 3A44A 5M3ML 5AI2A 1OWCA 3M4OL 1BQ9A 3QVDA 1NXGA 2PVXA 3I4NL 1DVBA 4TPUA 3GTJL 2JA6L 4ME3A 2Z3RB 4C2M1 8RXNA 2KKDA 1IW7D 2VUML 2O5JD 1NXEA 2CKAA 1OWBA 3KYWA 4A3GL 4JAFA 1PFYA 5AN9H 2R7ZL 4AI2A 5FLML 3PZAA 5DM61 1IROA 1R0IA 1T9QA 3P8BA 5C4JL 4A3BL 1PFWA 1YUZA 4X6AL 1LKOA 1S24A 1R0GA 4YWLA 1TWGL 5EIOC 1Y1WL 4AR3A 1CADA 3PWFA 1R0JA 3MSUA 3S2DL 2CR8A 4AHYA 4BY7L 2VL6A 3ZG6A 3GTML 1YK4A 3HOZL 3KYYA 3I4ML 1T9OA 1S30A 3HOYL 5MFZA 4BBSL 4A3LL 3S1NL 1RDVA 4AHXA 1YUXA 1VZIA 1IU6A 2ERSA 4XXBB 3GTPL 2V3BB 1CAAA 1NNQA 2JA8L 3RYGA 3JR7A 1SFOL 4UY81 4A3KL 3H97A 2ERJA 1R9TL 3HAXC 4A3DL 2HVYC 5IYDL 3S1ML 3HOVL 2APOB 2JI2A 4K9FA 4A93L 2NVYL 2AUSB 2KN9A 1TWCL 2JI3A 3HOUL 2AYJA 4AYBP 5DM71 3KYVA 4ZN1B 2R92L 2RDVA 2E2JL 4XGHA 3GTGL 1ZRPA 4BY1L 3GTQL 4POGA 2Y0SP 2E2IL 3HOXL 3S1RL 3LNLA 5M5YL 3FKIL 3LWRB 1BE7A 3LWVB 1VZHA 4Y7NL 1IU5A 1VZGA 3RZOL 2R93L 1B13A 2NVQL 1WCML 1SMUA 3PO2L 5JVG1 5H1Sc 4C3JL 4AI3A 4LHLA 5K2ME 3RZDL 3LWQB 2QL0A 4A3IL 1TWAL 1RDGA 2XJVA 4LHNA 3VPBE 1R0HA 1TWHL 4Y52L 2DSXA 5IP7L 1S2ZA 1TWFL 2PVEA 4ZN3B 4G6BA 2XJQA 2LCQA 2AQCA 3K35A 4JAEA 3WWLA 4AI1A 3HOWL 3S14L 3J7Z1 3J7Y1 4POFA 3WWNB 1VCXA 1RYQA 1JYBA 1RWDA 3GTKL 3B0AB 3H9BA 3LPEB 5GADc 2K2DA 3NFPI 4AR4A 1QCVA 6RXNA 2H12A 1QYBA 3H0GL 1BFYA 3B08B 1LTLA 3PO3L 2E2HL 2L0ZA 3S15L 5IYCL 3KYXA 4AI0A 3PKJA 1RB9A 2A6HD 5C44L 5C4XL 5MFPA 2HR5A 1H7VA 2NVXL 3S1QL 2EY4E 3S16L 3RZTA 3HJYB 1SMWA 1FHHA 4RXNA 1B2JA 1BQ8A 2NYDA 2XJTA 3MPSA 5C3EL 2MS3A 2PPTA 4TVMA 1R0FA 5GAEc 4B8CD 1T9PA 2C6BA 4JAGA 2NVTL 3QQCE 2A69D 3H3VM 2B63L 2BE5D 3K7AL 2XJRA 3PKIA 5M5XL 2Z3QB 1E8JA 3SS2A 1B71A 4BXXL 1WJVA 5JVH1 2WB1P 3KYUA 1YK5A 5MGNA 3H9CA 1Z92B 5IY0A 4AHWA 1B2OA 3P2AA 5RXNA 3HJWB 2RFKB 3LWOB 1YV1A 2V0EA 4QIWP 3M3YL 4V196 4A3JL 5AI3A 5IP9L 4BBRL 4WFN1 2WAQP 1RYTA 1BRFA 4AR6A 4AR5A 5MLC3 2J9UB 1LKPA 4A3EL 3PL5A 4JADA 2M4YA 2ZIXA 4C3HL 4A3FL 1DX8A 2XJSA 2PSMC 2YU9L 3H99A 4AHZA 5EINC 1SMMA 1IRNA 1ODHA 4U671 4C3IL 4A3CL 2A6ED 1I3QL 3S17L 4E6YA 1FHMA 2A68D 1I50L 5M3FL 3HKZP 1I6HL 3S2HL 2CKCA 4YWMA 2PMZP 7RXNA 3IU3I 3GTOL 2JA7L 1P7PA 3MQKB 2B5ID 4GS7D 1PFUA 1PZXA 5MF6A 2JA5L 3PIP1 2PYAA 5GAHc 1Y1VL 1QQTA 2GMGA 1K83L 1C09A 2M6PA 3PIO1 5GAGc 2V0FA 3CQZL 5IYBL 2M4VA 5M5WL 4A3ML 1LKMA 5FJ8L 3GTLL 1PFVA 3RZ6A 1F4LA 2M6OA 2JI1A 2XJUA
chains in the Genus database with same CATH topology
4BBRL 3GTKL 5M3ML 3HOVL 2WAQP 4A93L 2NVYL 1TWCL 3HOUL 3M4OL 3H0GL 3PO3L 4AYBP 2E2HL 3S15L 4A3EL 5IYCL 3I4NL 2JA6L 3GTJL 4C2M1 2R92L 5C44L 5C4XL 2E2JL 4C3HL 3GTGL 2VUML 4BY1L 4A3FL 2YU9L 3GTQL 2NVXL 3S1QL 3S16L 2Y0SP 4A3GL 4C3IL 2R7ZL 4A3CL 5FLML 1I3QL 2E2IL 3HOXL 3S1RL 5M5YL 3S17L 3FKIL 1I50L 4Y7NL 5M3FL 5C3EL 3HKZP 1I6HL 3S2HL 3RZOL 2R93L 2NVQL 5C4JL 2PMZP 4A3BL 4X6AL 1WCML 3GTOL 3PO2L 2JA7L 1TWGL 1Y1WL 2NVTL 3H3VM 2B63L 3K7AL 3S2DL 2JA5L 5M5XL 4C3JL 4BY7L 3GTML 4BXXL 3RZDL 3HOZL 3I4ML 4A3IL 1TWAL 1Y1VL 3HOYL 2WB1P 4Y52L 1TWHL 4BBSL 5IP7L 4A3LL 1K83L 1TWFL 3S1NL 3GTPL 2JA8L 3CQZL 5IYBL 4QIWP 4A3ML 5M5WL 5FJ8L 1SFOL 3M3YL 4A3KL 3GTLL 3HOWL 1R9TL 3S14L 4A3DL 4A3JL 5IYDL 3S1ML 5IP9L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BBR L;  3GTK L;  5M3M L;  3HOV L;  2WAQ P;  4A93 L;  2NVY L;  1TWC L;  3HOU L;  3M4O L;  3H0G L;  3PO3 L;  4AYB P;  2E2H L;  3S15 L;  4A3E L;  5IYC L;  3I4N L;  2JA6 L;  3GTJ L;  4C2M 1;  2R92 L;  5C44 L;  5C4X L;  2E2J L;  4C3H L;  3GTG L;  2VUM L;  4BY1 L;  4A3F L;  2YU9 L;  3GTQ L;  2NVX L;  3S1Q L;  3S16 L;  2Y0S P;  4A3G L;  4C3I L;  2R7Z L;  4A3C L;  5FLM L;  1I3Q L;  2E2I L;  3HOX L;  3S1R L;  5M5Y L;  3S17 L;  3FKI L;  1I50 L;  4Y7N L;  5M3F L;  5C3E L;  3HKZ P;  1I6H L;  3S2H L;  3RZO L;  2R93 L;  2NVQ L;  5C4J L;  2PMZ P;  4A3B L;  4X6A L;  1WCM L;  3GTO L;  3PO2 L;  2JA7 L;  1TWG L;  1Y1W L;  2NVT L;  3H3V M;  2B63 L;  3K7A L;  3S2D L;  2JA5 L;  5M5X L;  4C3J L;  4BY7 L;  3GTM L;  4BXX L;  3RZD L;  3HOZ L;  3I4M L;  4A3I L;  1TWA L;  1Y1V L;  3HOY L;  2WB1 P;  4Y52 L;  1TWH L;  4BBS L;  5IP7 L;  4A3L L;  1K83 L;  1TWF L;  3S1N L;  3GTP L;  2JA8 L;  3CQZ L;  5IYB L;  4QIW P;  4A3M L;  5M5W L;  5FJ8 L;  1SFO L;  3M3Y L;  4A3K L;  3GTL L;  3HOW L;  1R9T L;  3S14 L;  4A3D L;  4A3J L;  5IYD L;  3S1M L;  5IP9 L; 
#chains in the Genus database with same CATH topology
 3FDJ A;  3LWP B;  2C6A A;  2XJP A;  3A44 A;  5M3M L;  5AI2 A;  1OWC A;  3M4O L;  1BQ9 A;  3QVD A;  1NXG A;  2PVX A;  3I4N L;  1DVB A;  4TPU A;  3GTJ L;  2JA6 L;  4ME3 A;  2Z3R B;  4C2M 1;  8RXN A;  2KKD A;  1IW7 D;  2VUM L;  2O5J D;  1NXE A;  2CKA A;  1OWB A;  3KYW A;  4A3G L;  4JAF A;  1PFY A;  5AN9 H;  2R7Z L;  4AI2 A;  5FLM L;  3PZA A;  5DM6 1;  1IRO A;  1R0I A;  1T9Q A;  3P8B A;  5C4J L;  4A3B L;  1PFW A;  1YUZ A;  4X6A L;  1LKO A;  1S24 A;  1R0G A;  4YWL A;  1TWG L;  5EIO C;  1Y1W L;  4AR3 A;  1CAD A;  3PWF A;  1R0J A;  3MSU A;  3S2D L;  2CR8 A;  4AHY A;  4BY7 L;  2VL6 A;  3ZG6 A;  3GTM L;  1YK4 A;  3HOZ L;  3KYY A;  3I4M L;  1T9O A;  1S30 A;  3HOY L;  5MFZ A;  4BBS L;  4A3L L;  3S1N L;  1RDV A;  4AHX A;  1YUX A;  1VZI A;  1IU6 A;  2ERS A;  4XXB B;  3GTP L;  2V3B B;  1CAA A;  1NNQ A;  2JA8 L;  3RYG A;  3JR7 A;  1SFO L;  4UY8 1;  4A3K L;  3H97 A;  2ERJ A;  1R9T L;  3HAX C;  4A3D L;  2HVY C;  5IYD L;  3S1M L;  3HOV L;  2APO B;  2JI2 A;  4K9F A;  4A93 L;  2NVY L;  2AUS B;  2KN9 A;  1TWC L;  2JI3 A;  3HOU L;  2AYJ A;  4AYB P;  5DM7 1;  3KYV A;  4ZN1 B;  2R92 L;  2RDV A;  2E2J L;  4XGH A;  3GTG L;  1ZRP A;  4BY1 L;  3GTQ L;  4POG A;  2Y0S P;  2E2I L;  3HOX L;  3S1R L;  3LNL A;  5M5Y L;  3FKI L;  3LWR B;  1BE7 A;  3LWV B;  1VZH A;  4Y7N L;  1IU5 A;  1VZG A;  3RZO L;  2R93 L;  1B13 A;  2NVQ L;  1WCM L;  1SMU A;  3PO2 L;  5JVG 1;  5H1S c;  4C3J L;  4AI3 A;  4LHL A;  5K2M E;  3RZD L;  3LWQ B;  2QL0 A;  4A3I L;  1TWA L;  1RDG A;  2XJV A;  4LHN A;  3VPB E;  1R0H A;  1TWH L;  4Y52 L;  2DSX A;  5IP7 L;  1S2Z A;  1TWF L;  2PVE A;  4ZN3 B;  4G6B A;  2XJQ A;  2LCQ A;  2AQC A;  3K35 A;  4JAE A;  3WWL A;  4AI1 A;  3HOW L;  3S14 L;  3J7Z 1;  3J7Y 1;  4POF A;  3WWN B;  1VCX A;  1RYQ A;  1JYB A;  1RWD A;  3GTK L;  3B0A B;  3H9B A;  3LPE B;  5GAD c;  2K2D A;  3NFP I;  4AR4 A;  1QCV A;  6RXN A;  2H12 A;  1QYB A;  3H0G L;  1BFY A;  3B08 B;  1LTL A;  3PO3 L;  2E2H L;  2L0Z A;  3S15 L;  5IYC L;  3KYX A;  4AI0 A;  3PKJ A;  1RB9 A;  2A6H D;  5C44 L;  5C4X L;  5MFP A;  2HR5 A;  1H7V A;  2NVX L;  3S1Q L;  2EY4 E;  3S16 L;  3RZT A;  3HJY B;  1SMW A;  1FHH A;  4RXN A;  1B2J A;  1BQ8 A;  2NYD A;  2XJT A;  3MPS A;  5C3E L;  2MS3 A;  2PPT A;  4TVM A;  1R0F A;  5GAE c;  4B8C D;  1T9P A;  2C6B A;  4JAG A;  2NVT L;  3QQC E;  2A69 D;  3H3V M;  2B63 L;  2BE5 D;  3K7A L;  2XJR A;  3PKI A;  5M5X L;  2Z3Q B;  1E8J A;  3SS2 A;  1B71 A;  4BXX L;  1WJV A;  5JVH 1;  2WB1 P;  3KYU A;  1YK5 A;  5MGN A;  3H9C A;  1Z92 B;  5IY0 A;  4AHW A;  1B2O A;  3P2A A;  5RXN A;  3HJW B;  2RFK B;  3LWO B;  1YV1 A;  2V0E A;  4QIW P;  3M3Y L;  4V19 6;  4A3J L;  5AI3 A;  5IP9 L;  4BBR L;  4WFN 1;  2WAQ P;  1RYT A;  1BRF A;  4AR6 A;  4AR5 A;  5MLC 3;  2J9U B;  1LKP A;  4A3E L;  3PL5 A;  4JAD A;  2M4Y A;  2ZIX A;  4C3H L;  4A3F L;  1DX8 A;  2XJS A;  2PSM C;  2YU9 L;  3H99 A;  4AHZ A;  5EIN C;  1SMM A;  1IRN A;  1ODH A;  4U67 1;  4C3I L;  4A3C L;  2A6E D;  1I3Q L;  3S17 L;  4E6Y A;  1FHM A;  2A68 D;  1I50 L;  5M3F L;  3HKZ P;  1I6H L;  3S2H L;  2CKC A;  4YWM A;  2PMZ P;  7RXN A;  3IU3 I;  3GTO L;  2JA7 L;  1P7P A;  3MQK B;  2B5I D;  4GS7 D;  1PFU A;  1PZX A;  5MF6 A;  2JA5 L;  3PIP 1;  2PYA A;  5GAH c;  1Y1V L;  1QQT A;  2GMG A;  1K83 L;  1C09 A;  2M6P A;  3PIO 1;  5GAG c;  2V0F A;  3CQZ L;  5IYB L;  2M4V A;  5M5W L;  4A3M L;  1LKM A;  5FJ8 L;  3GTL L;  1PFV A;  3RZ6 A;  1F4L A;  2M6O A;  2JI1 A;  2XJU A; 
#chains in the Genus database with same CATH homology
 4BBR L;  3GTK L;  5M3M L;  3HOV L;  2WAQ P;  4A93 L;  2NVY L;  1TWC L;  3HOU L;  3M4O L;  3H0G L;  3PO3 L;  4AYB P;  2E2H L;  3S15 L;  4A3E L;  5IYC L;  3I4N L;  2JA6 L;  3GTJ L;  4C2M 1;  2R92 L;  5C44 L;  5C4X L;  2E2J L;  4C3H L;  3GTG L;  2VUM L;  4BY1 L;  4A3F L;  2YU9 L;  3GTQ L;  2NVX L;  3S1Q L;  3S16 L;  2Y0S P;  4A3G L;  4C3I L;  2R7Z L;  4A3C L;  5FLM L;  1I3Q L;  2E2I L;  3HOX L;  3S1R L;  5M5Y L;  3S17 L;  3FKI L;  1I50 L;  4Y7N L;  5M3F L;  5C3E L;  3HKZ P;  1I6H L;  3S2H L;  3RZO L;  2R93 L;  2NVQ L;  5C4J L;  2PMZ P;  4A3B L;  4X6A L;  1WCM L;  3GTO L;  3PO2 L;  2JA7 L;  1TWG L;  1Y1W L;  2NVT L;  3H3V M;  2B63 L;  3K7A L;  3S2D L;  2JA5 L;  5M5X L;  4C3J L;  4BY7 L;  3GTM L;  4BXX L;  3RZD L;  3HOZ L;  3I4M L;  4A3I L;  1TWA L;  1Y1V L;  3HOY L;  2WB1 P;  4Y52 L;  1TWH L;  4BBS L;  5IP7 L;  4A3L L;  1K83 L;  1TWF L;  3S1N L;  3GTP L;  2JA8 L;  3CQZ L;  5IYB L;  4QIW P;  4A3M L;  5M5W L;  5FJ8 L;  1SFO L;  3M3Y L;  4A3K L;  3GTL L;  3HOW L;  1R9T L;  3S14 L;  4A3D L;  4A3J L;  5IYD L;  3S1M L;  5IP9 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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