2Z3RB

Crystal structure of the il-15/il-15ra complex
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
74
structure length
74
Chain Sequence
SITCPPPMSVEHADIWVKSYSLYSRERYICNSGFKRKAGTSSLTECVLNKATNVAHWTTPSLKCIRDPALVHQR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans
pubmed doi rcsb
molecule tags Cytokine/cytokine receptor
source organism Homo sapiens
molecule keywords Interleukin-15
total genus 13
structure length 74
sequence length 74
chains with identical sequence D, F, H, J, L, N, P
ec nomenclature
pdb deposition date 2007-06-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.230 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2z3rB01
2ERSA 2B5ID 2Z3RB 4GS7D 3IU3I 2PSMC 2Z3QB 2ERJA 1Z92B 3NFPI
chains in the Genus database with same CATH superfamily
5GAGc 3IU3I 1YUZA 1C09A 1TWCL 7RXNA 4B8CD 5GADc 2NVXL 2J9UB 5C44L 3HAXC 1WJVA 2ERJA 8RXNA 2XJUA 1PFYA 4AYBP 3PL5A 4AI2A 1NXEA 4A3DL 4A3KL 2PSMC 3H0GL 2PVXA 3LPEB 2XJRA 5C4JL 5JVG1 5JVH1 1YK5A 2XJTA 1YV1A 3LNLA 3S17L 1IU5A 5AI2A 5RXNA 4AI0A 3S1NL 2O5JD 3HKZP 1RB9A 2NVTL 1E8JA 2XJVA 3PIO1 2KKDA 2RFKB 2YU9L 2HVYC 1T9QA 3WWLA 3VPBE 2QL0A 4C3IL 2M6PA 1BFYA 4AR4A 4XGHA 3FDJA 5IP7L 4E6YA 1IRNA 4ME3A 5C4XL 4C2M1 1DX8A 5MLC3 4X6AL 4TVMA 4A3IL 6RXNA 5DM61 1PFUA 1VZIA 1R0GA 3FKIL 1BRFA 2WB1P 4V196 5AI3A 5M5XL 3GTLL 1I3QL 3LWRB 4AHXA 4K9FA 3NFPI 3QQCE 4ZN1B 1QYBA 5M5WL 4A3LL 4BY7L 1T9OA 1H7VA 1VZGA 2E2JL 3B08B 2KN9A 1NNQA 2R93L 4QIWP 5MF6A 3KYXA 4AHYA 4WFN1 3HJYB 3WWNB 1FHMA 3S14L 2PVEA 4BY1L 3MQKB 2MS3A 4A93L 2Z3QB 4AI1A 3GTJL 1S30A 4BBRL 4G6BA 4A3EL 5H1Sc 1CADA 1YUXA 3QVDA 5K2ME 3KYUA 2NVYL 2JI1A 3LWVB 1QCVA 4ZN3B 1IROA 3S1RL 2A6ED 1TWGL 5IYBL 3HJWB 3P8BA 4A3BL 3PZAA 4TPUA 1I50L 1NXGA 2DSXA 5FJ8L 3S15L 2JI3A 2ERSA 1IU6A 4AR5A 5DM71 2CR8A 2R7ZL 4BBSL 2JA7L 3PO3L 2BE5D 1RYQA 2Z3RB 4YWMA 3HOVL 3H99A 1SMUA 3S16L 1IW7D 4A3ML 2JA5L 3J7Y1 2RDVA 1JYBA 2V0EA 2NYDA 1QQTA 2E2IL 2M4YA 1CAAA 5MFZA 2PMZP 2XJPA 1TWAL 1YK4A 1T9PA 5M3ML 3GTOL 4UY81 2XJQA 2AQCA 1R0IA 4BXXL 4GS7D 1S24A 1RDGA 1B2OA 1K83L 2WAQP 1BE7A 1ZRPA 5EIOC 3J7Z1 3M4OL 5M3FL 3I4NL 1DVBA 2A69D 1B13A 1BQ8A 2XJSA 2CKCA 4XXBB 3MSUA 2VUML 5IYDL 2JA6L 1RDVA 3GTML 3RYGA 1RWDA 3RZTA 3CQZL 3ZG6A 3LWPB 2AYJA 5M5YL 4U671 5IYCL 3K35A 3HOUL 4Y7NL 5FLML 3H9CA 5AN9H 3PKJA 4JADA 1SMWA 4YWLA 1ODHA 2CKAA 3MPSA 4POGA 3H97A 1FHHA 2V0FA 1TWHL 2L0ZA 1R0FA 1S2ZA 5GAHc 1VZHA 3KYYA 3PKIA 3S2HL 5IY0A 2H12A 4AR3A 2B63L 3PWFA 4JAEA 1I6HL 1P7PA 3GTGL 1R0JA 1LKOA 2R92L 5GAEc 1LKPA 2B5ID 2NVQL 2AUSB 4LHLA 2ZIXA 1PZXA 2V3BB 4C3JL 1BQ9A 1Z92B 1PFWA 1TWFL 3RZ6A 1OWCA 1SMMA 4A3CL 2A6HD 4JAGA 1B71A 3M3YL 2LCQA 2Y0SP 2JA8L 4JAFA 2M6OA 3S1QL 3KYVA 2C6BA 4A3GL 5IP9L 2APOB 3HOXL 3H9BA 3RZOL 2E2HL 1R0HA 3S2DL 3SS2A 4C3HL 3H3VM 4AI3A 2PYAA 1F4LA 3JR7A 3K7AL 3LWQB 2GMGA 3B0AB 2C6AA 1OWBA 3HOWL 1Y1WL 3GTPL 1VCXA 1RYTA 4AR6A 3KYWA 1PFVA 5MFPA 3HOZL 2K2DA 5C3EL 2HR5A 4RXNA 4A3FL 3S1ML 3I4ML 4POFA 3P2AA 3PO2L 2M4VA 1LTLA 2JI2A 3A44A 3GTKL 4Y52L 2EY4E 3RZDL 1R9TL 3HOYL 5EINC 2VL6A 4A3JL 1WCML 2PPTA 1Y1VL 2A68D 3GTQL 1LKMA 4LHNA 1SFOL 4AHZA 5MGNA 1B2JA 3PIP1 4AHWA 3LWOB
chains in the Genus database with same CATH topology
1R0GA 2XJPA 1YK4A 5GAGc 1T9PA 3IU3I 1R0JA 1BRFA 4V196 1YUZA 4UY81 1C09A 1LKOA 5AI3A 5GAEc 4AHXA 1LKPA 2B5ID 2XJQA 4LHLA 7RXNA 2ZIXA 4K9FA 4B8CD 3NFPI 3QQCE 2V3BB 1R0IA 4ZN1B 1QYBA 5GADc 1T9OA 4GS7D 1S24A 1H7VA 1VZGA 3B08B 2KN9A 1BQ9A 1Z92B 1RDGA 1NNQA 2J9UB 1B2OA 1WJVA 2ERJA 3RZ6A 5MF6A 1BE7A 1OWCA 1ZRPA 1SMMA 5EIOC 3KYXA 4AHYA 8RXNA 4WFN1 3J7Z1 2XJUA 2A6HD 4JAGA 1B71A 1DVBA 3WWNB 1FHMA 4AI2A 1NXEA 2LCQA 2A69D 2PVEA 4JAFA 1B13A 2MS3A 2PSMC 2Z3QB 2M6OA 3KYVA 1BQ8A 2PVXA 2XJSA 4AI1A 2C6BA 2CKCA 1S30A 4G6BA 4XXBB 3MSUA 5H1Sc 1CADA 1YUXA 3QVDA 3LPEB 5K2ME 2XJRA 1RDVA 5JVG1 1R0HA 5JVH1 1YK5A 3KYUA 3SS2A 3RYGA 1RWDA 3RZTA 2JI1A 1QCVA 4ZN3B 2XJTA 1IROA 4AI3A 1YV1A 3LNLA 2PYAA 2A6ED 3ZG6A 1IU5A 5AI2A 2GMGA 2AYJA 3P8BA 5RXNA 4U671 3PZAA 3B0AB 4AI0A 4TPUA 2C6AA 3K35A 1OWBA 1NXGA 2DSXA 1VCXA 2JI3A 5DM61 1RYTA 2ERSA 1IU6A 5AN9H 4AR6A 3KYWA 3PKJA 2O5JD 4JADA 1SMWA 4AHWA 1RB9A 4AR5A 5MFPA 5DM71 2K2DA 4YWLA 1ODHA 2CKAA 1E8JA 3MPSA 2CR8A 4POGA 2HR5A 2XJVA 4RXNA 3PIO1 2KKDA 4POFA 1FHHA 1T9QA 2V0FA 3P2AA 2BE5D 3WWLA 3VPBE 1RYQA 2L0ZA 1LTLA 2M4VA 2JI2A 2QL0A 2Z3RB 3A44A 4YWMA 2M6PA 1R0FA 1SMUA 1BFYA 4AR4A 1S2ZA 4XGHA 1IW7D 5GAHc 4E6YA 5EINC 1IRNA 1VZHA 4ME3A 3KYYA 2VL6A 3J7Y1 2PPTA 2A68D 1LKMA 2RDVA 3PKIA 1DX8A 5IY0A 4LHNA 5MLC3 4AHZA 1JYBA 2H12A 2NYDA 2V0EA 4TVMA 4AR3A 5MGNA 1B2JA 3PIP1 3PWFA 2M4YA 4JAEA 1CAAA 6RXNA 5MFZA 1VZIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ERS A;  2B5I D;  2Z3R B;  4GS7 D;  3IU3 I;  2PSM C;  2Z3Q B;  2ERJ A;  1Z92 B;  3NFP I; 
#chains in the Genus database with same CATH topology
 5GAG c;  3IU3 I;  1YUZ A;  1C09 A;  1TWC L;  7RXN A;  4B8C D;  5GAD c;  2NVX L;  2J9U B;  5C44 L;  3HAX C;  1WJV A;  2ERJ A;  8RXN A;  2XJU A;  1PFY A;  4AYB P;  3PL5 A;  4AI2 A;  1NXE A;  4A3D L;  4A3K L;  2PSM C;  3H0G L;  2PVX A;  3LPE B;  2XJR A;  5C4J L;  5JVG 1;  5JVH 1;  1YK5 A;  2XJT A;  1YV1 A;  3LNL A;  3S17 L;  1IU5 A;  5AI2 A;  5RXN A;  4AI0 A;  3S1N L;  2O5J D;  3HKZ P;  1RB9 A;  2NVT L;  1E8J A;  2XJV A;  3PIO 1;  2KKD A;  2RFK B;  2YU9 L;  2HVY C;  1T9Q A;  3WWL A;  3VPB E;  2QL0 A;  4C3I L;  2M6P A;  1BFY A;  4AR4 A;  4XGH A;  3FDJ A;  5IP7 L;  4E6Y A;  1IRN A;  4ME3 A;  5C4X L;  4C2M 1;  1DX8 A;  5MLC 3;  4X6A L;  4TVM A;  4A3I L;  6RXN A;  5DM6 1;  1PFU A;  1VZI A;  1R0G A;  3FKI L;  1BRF A;  2WB1 P;  4V19 6;  5AI3 A;  5M5X L;  3GTL L;  1I3Q L;  3LWR B;  4AHX A;  4K9F A;  3NFP I;  3QQC E;  4ZN1 B;  1QYB A;  5M5W L;  4A3L L;  4BY7 L;  1T9O A;  1H7V A;  1VZG A;  2E2J L;  3B08 B;  2KN9 A;  1NNQ A;  2R93 L;  4QIW P;  5MF6 A;  3KYX A;  4AHY A;  4WFN 1;  3HJY B;  3WWN B;  1FHM A;  3S14 L;  2PVE A;  4BY1 L;  3MQK B;  2MS3 A;  4A93 L;  2Z3Q B;  4AI1 A;  3GTJ L;  1S30 A;  4BBR L;  4G6B A;  4A3E L;  5H1S c;  1CAD A;  1YUX A;  3QVD A;  5K2M E;  3KYU A;  2NVY L;  2JI1 A;  3LWV B;  1QCV A;  4ZN3 B;  1IRO A;  3S1R L;  2A6E D;  1TWG L;  5IYB L;  3HJW B;  3P8B A;  4A3B L;  3PZA A;  4TPU A;  1I50 L;  1NXG A;  2DSX A;  5FJ8 L;  3S15 L;  2JI3 A;  2ERS A;  1IU6 A;  4AR5 A;  5DM7 1;  2CR8 A;  2R7Z L;  4BBS L;  2JA7 L;  3PO3 L;  2BE5 D;  1RYQ A;  2Z3R B;  4YWM A;  3HOV L;  3H99 A;  1SMU A;  3S16 L;  1IW7 D;  4A3M L;  2JA5 L;  3J7Y 1;  2RDV A;  1JYB A;  2V0E A;  2NYD A;  1QQT A;  2E2I L;  2M4Y A;  1CAA A;  5MFZ A;  2PMZ P;  2XJP A;  1TWA L;  1YK4 A;  1T9P A;  5M3M L;  3GTO L;  4UY8 1;  2XJQ A;  2AQC A;  1R0I A;  4BXX L;  4GS7 D;  1S24 A;  1RDG A;  1B2O A;  1K83 L;  2WAQ P;  1BE7 A;  1ZRP A;  5EIO C;  3J7Z 1;  3M4O L;  5M3F L;  3I4N L;  1DVB A;  2A69 D;  1B13 A;  1BQ8 A;  2XJS A;  2CKC A;  4XXB B;  3MSU A;  2VUM L;  5IYD L;  2JA6 L;  1RDV A;  3GTM L;  3RYG A;  1RWD A;  3RZT A;  3CQZ L;  3ZG6 A;  3LWP B;  2AYJ A;  5M5Y L;  4U67 1;  5IYC L;  3K35 A;  3HOU L;  4Y7N L;  5FLM L;  3H9C A;  5AN9 H;  3PKJ A;  4JAD A;  1SMW A;  4YWL A;  1ODH A;  2CKA A;  3MPS A;  4POG A;  3H97 A;  1FHH A;  2V0F A;  1TWH L;  2L0Z A;  1R0F A;  1S2Z A;  5GAH c;  1VZH A;  3KYY A;  3PKI A;  3S2H L;  5IY0 A;  2H12 A;  4AR3 A;  2B63 L;  3PWF A;  4JAE A;  1I6H L;  1P7P A;  3GTG L;  1R0J A;  1LKO A;  2R92 L;  5GAE c;  1LKP A;  2B5I D;  2NVQ L;  2AUS B;  4LHL A;  2ZIX A;  1PZX A;  2V3B B;  4C3J L;  1BQ9 A;  1Z92 B;  1PFW A;  1TWF L;  3RZ6 A;  1OWC A;  1SMM A;  4A3C L;  2A6H D;  4JAG A;  1B71 A;  3M3Y L;  2LCQ A;  2Y0S P;  2JA8 L;  4JAF A;  2M6O A;  3S1Q L;  3KYV A;  2C6B A;  4A3G L;  5IP9 L;  2APO B;  3HOX L;  3H9B A;  3RZO L;  2E2H L;  1R0H A;  3S2D L;  3SS2 A;  4C3H L;  3H3V M;  4AI3 A;  2PYA A;  1F4L A;  3JR7 A;  3K7A L;  3LWQ B;  2GMG A;  3B0A B;  2C6A A;  1OWB A;  3HOW L;  1Y1W L;  3GTP L;  1VCX A;  1RYT A;  4AR6 A;  3KYW A;  1PFV A;  5MFP A;  3HOZ L;  2K2D A;  5C3E L;  2HR5 A;  4RXN A;  4A3F L;  3S1M L;  3I4M L;  4POF A;  3P2A A;  3PO2 L;  2M4V A;  1LTL A;  2JI2 A;  3A44 A;  3GTK L;  4Y52 L;  2EY4 E;  3RZD L;  1R9T L;  3HOY L;  5EIN C;  2VL6 A;  4A3J L;  1WCM L;  2PPT A;  1Y1V L;  2A68 D;  3GTQ L;  1LKM A;  4LHN A;  1SFO L;  4AHZ A;  5MGN A;  1B2J A;  3PIP 1;  4AHW A;  3LWO B; 
#chains in the Genus database with same CATH homology
 1R0G A;  2XJP A;  1YK4 A;  5GAG c;  1T9P A;  3IU3 I;  1R0J A;  1BRF A;  4V19 6;  1YUZ A;  4UY8 1;  1C09 A;  1LKO A;  5AI3 A;  5GAE c;  4AHX A;  1LKP A;  2B5I D;  2XJQ A;  4LHL A;  7RXN A;  2ZIX A;  4K9F A;  4B8C D;  3NFP I;  3QQC E;  2V3B B;  1R0I A;  4ZN1 B;  1QYB A;  5GAD c;  1T9O A;  4GS7 D;  1S24 A;  1H7V A;  1VZG A;  3B08 B;  2KN9 A;  1BQ9 A;  1Z92 B;  1RDG A;  1NNQ A;  2J9U B;  1B2O A;  1WJV A;  2ERJ A;  3RZ6 A;  5MF6 A;  1BE7 A;  1OWC A;  1ZRP A;  1SMM A;  5EIO C;  3KYX A;  4AHY A;  8RXN A;  4WFN 1;  3J7Z 1;  2XJU A;  2A6H D;  4JAG A;  1B71 A;  1DVB A;  3WWN B;  1FHM A;  4AI2 A;  1NXE A;  2LCQ A;  2A69 D;  2PVE A;  4JAF A;  1B13 A;  2MS3 A;  2PSM C;  2Z3Q B;  2M6O A;  3KYV A;  1BQ8 A;  2PVX A;  2XJS A;  4AI1 A;  2C6B A;  2CKC A;  1S30 A;  4G6B A;  4XXB B;  3MSU A;  5H1S c;  1CAD A;  1YUX A;  3QVD A;  3LPE B;  5K2M E;  2XJR A;  1RDV A;  5JVG 1;  1R0H A;  5JVH 1;  1YK5 A;  3KYU A;  3SS2 A;  3RYG A;  1RWD A;  3RZT A;  2JI1 A;  1QCV A;  4ZN3 B;  2XJT A;  1IRO A;  4AI3 A;  1YV1 A;  3LNL A;  2PYA A;  2A6E D;  3ZG6 A;  1IU5 A;  5AI2 A;  2GMG A;  2AYJ A;  3P8B A;  5RXN A;  4U67 1;  3PZA A;  3B0A B;  4AI0 A;  4TPU A;  2C6A A;  3K35 A;  1OWB A;  1NXG A;  2DSX A;  1VCX A;  2JI3 A;  5DM6 1;  1RYT A;  2ERS A;  1IU6 A;  5AN9 H;  4AR6 A;  3KYW A;  3PKJ A;  2O5J D;  4JAD A;  1SMW A;  4AHW A;  1RB9 A;  4AR5 A;  5MFP A;  5DM7 1;  2K2D A;  4YWL A;  1ODH A;  2CKA A;  1E8J A;  3MPS A;  2CR8 A;  4POG A;  2HR5 A;  2XJV A;  4RXN A;  3PIO 1;  2KKD A;  4POF A;  1FHH A;  1T9Q A;  2V0F A;  3P2A A;  2BE5 D;  3WWL A;  3VPB E;  1RYQ A;  2L0Z A;  1LTL A;  2M4V A;  2JI2 A;  2QL0 A;  2Z3R B;  3A44 A;  4YWM A;  2M6P A;  1R0F A;  1SMU A;  1BFY A;  4AR4 A;  1S2Z A;  4XGH A;  1IW7 D;  5GAH c;  4E6Y A;  5EIN C;  1IRN A;  1VZH A;  4ME3 A;  3KYY A;  2VL6 A;  3J7Y 1;  2PPT A;  2A68 D;  1LKM A;  2RDV A;  3PKI A;  1DX8 A;  5IY0 A;  4LHN A;  5MLC 3;  4AHZ A;  1JYB A;  2H12 A;  2NYD A;  2V0E A;  4TVM A;  4AR3 A;  5MGN A;  1B2J A;  3PIP 1;  3PWF A;  2M4Y A;  4JAE A;  1CAA A;  6RXN A;  5MFZ A;  1VZI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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