2C6AA

Solution structure of the c4 zinc-finger domain of hdm2
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
46
structure length
46
Chain Sequence
SFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structure of the C4 Zinc Finger Domain of Hdm2.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords UBIQUITIN-PROTEIN LIGASE E3 MDM2
total genus 3
structure length 46
sequence length 46
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2005-11-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00641 zf-RanBP Zn-finger in Ran binding protein and others
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.140 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2c6aA00
3P2AA 2PPTA 2C6AA 2J9UB 3B0AB 2C6BA 4XXBB 3B08B
chains in the Genus database with same CATH superfamily
2NVYL 3PO3L 2C6AA 1LTLA 3I4NL 3J7Y1 5C44L 2Z3QB 1IU5A 1RWDA 1YK4A 1OWBA 5MLC3 5IYBL 3ZG6A 3LWVB 3HAXC 4G6BA 5MF6A 1TWGL 1BRFA 3B0AB 5AN9H 5JVG1 3I4ML 1H7VA 3MPSA 2RDVA 4JADA 4ZN3B 3H9CA 3H97A 1R0JA 1VZIA 3S1NL 5M3FL 3KYYA 1TWHL 5K2ME 3HJYB 5IP7L 1T9QA 4AR6A 2KN9A 4Y52L 3RZTA 4JAEA 5FJ8L 2AUSB 2A69D 5C3EL 1SMWA 2J9UB 1BQ8A 3CQZL 4WFN1 3KYVA 3P2AA 2APOB 8RXNA 2M4VA 4BY7L 5C4XL 2R93L 3FKIL 2PMZP 2MS3A 3HOVL 1RDGA 4YWLA 1RB9A 2CR8A 3B08B 3S2HL 1CAAA 3SS2A 1IU6A 3H0GL 3S17L 4E6YA 4K9FA 1S24A 5EINC 2PPTA 4AR5A 2LCQA 3S16L 3LNLA 3VPBE 4QIWP 4XGHA 4POFA 3LWQB 3HKZP 3QVDA 3S1RL 4X6AL 4ME3A 2XJTA 5H1Sc 3P8BA 3HOZL 1ODHA 2A6ED 4A3CL 2XJSA 1TWFL 5IYCL 4TVMA 1B2JA 3RZ6A 1QYBA 1VCXA 1YK5A 3S2DL 3KYXA 1TWCL 3LWOB 3PIP1 1WJVA 3A44A 1VZGA 1SFOL 4AI0A 5IP9L 1FHMA 2ERSA 3GTGL 1R9TL 1R0HA 1I3QL 5MFPA 3S1ML 1YUZA 4LHLA 2NVXL 2A6HD 2DSXA 1LKOA 3JR7A 3HOUL 1NXGA 1Y1VL 2CKCA 1B71A 2E2IL 1SMUA 2M4YA 5RXNA 4A3IL 2M6PA 3QQCE 2PVXA 2NVQL 1B13A 5IY0A 1BE7A 1DVBA 2ERJA 4C3HL 1DX8A 1VZHA 4RXNA 2H12A 1R0GA 1PZXA 2ZIXA 4AR3A 2K2DA 2Y0SP 4BY1L 4C3JL 6RXNA 1I6HL 3PKIA 3PWFA 1WCML 5IYDL 1RDVA 4C2M1 4GS7D 2GMGA 2BE5D 1BQ9A 2XJPA 4AI3A 2NVTL 1OWCA 2M6OA 1IW7D 2V3BB 4A3LL 2R92L 4Y7NL 2A68D 2E2JL 4A3FL 1R0FA 4AHZA 2JA7L 1T9OA 2B5ID 4LHNA 1PFWA 1QCVA 4AI1A 3HJWB 3GTPL 1YUXA 1S30A 3GTML 3LWPB 3KYUA 1ZRPA 3LPEB 3NFPI 5AI2A 2RFKB 4AR4A 1PFYA 1PFUA 3PIO1 2NYDA 4V196 4AHWA 2YU9L 2C6BA 3PL5A 4AI2A 1NXEA 1LKPA 2XJVA 2HR5A 2XJQA 3HOXL 3HOYL 2QL0A 1CADA 4JAFA 4A3ML 2PSMC 1RYTA 5GADc 4XXBB 5DM71 4BXXL 3PO2L 5GAGc 3K7AL 4A3EL 4C3IL 4BBRL 2JI1A 4A3GL 2EY4E 1FHHA 1P7PA 5EIOC 4BBSL 5C4JL 5JVH1 3S14L 5GAEc 3S1QL 1PFVA 1YV1A 5M5XL 1T9PA 2V0EA 1SMMA 2VL6A 2CKAA 1TWAL 3PKJA 5M3ML 5M5WL 2XJRA 2JA8L 3M3YL 3MSUA 2WB1P 1R0IA 3RZOL 4AYBP 2PVEA 3RZDL 3WWLA 4B8CD 3J7Z1 2R7ZL 1B2OA 3FDJA 5M5YL 1E8JA 4U671 3GTOL 3H9BA 3H3VM 1K83L 2WAQP 5AI3A 1JYBA 4UY81 1RYQA 3PZAA 4AHYA 3S15L 1Z92B 2JA6L 4AHXA 4A3JL 1NNQA 2HVYC 1F4LA 1BFYA 4A3BL 5MGNA 2AYJA 3HOWL 2PYAA 5GAHc 3WWNB 4A93L 2XJUA 2VUML 1I50L 3IU3I 1IROA 1LKMA 5DM61 3M4OL 1Y1WL 4ZN1B 2JI3A 1QQTA 2O5JD 2KKDA 3KYWA 3GTLL 3GTQL 7RXNA 1IRNA 4A3KL 2AQCA 5FLML 4POGA 2JI2A 3GTKL 1C09A 5MFZA 3GTJL 3RYGA 3H99A 2V0FA 4TPUA 4JAGA 3K35A 3MQKB 4YWMA 2JA5L 2Z3RB 1S2ZA 2B63L 4A3DL 3LWRB 2E2HL 2L0ZA
chains in the Genus database with same CATH topology
5EIOC 5EINC 2PPTA 5JVH1 1RDVA 5GAEc 4GS7D 1YV1A 2GMGA 4AR5A 1T9PA 2C6AA 2BE5D 2V0EA 1LTLA 1SMMA 2VL6A 3LNLA 1BQ9A 2XJPA 2CKAA 2LCQA 4AI3A 3PKJA 3VPBE 4XGHA 1OWCA 2M6OA 3J7Y1 2XJRA 1IW7D 2V3BB 2Z3QB 4POFA 1IU5A 1RWDA 1YK4A 2A68D 3QVDA 1OWBA 5MLC3 3MSUA 1R0FA 4AHZA 1R0IA 3ZG6A 4ME3A 2PVEA 1T9OA 2XJTA 5H1Sc 4G6BA 3P8BA 2B5ID 4LHNA 1QCVA 3WWLA 4AI1A 4B8CD 5MF6A 3J7Z1 1BRFA 2A6ED 1B2OA 1ODHA 2XJSA 3B0AB 5AN9H 1E8JA 4TVMA 4U671 1B2JA 3RZ6A 5JVG1 1QYBA 1VCXA 1H7VA 3MPSA 2RDVA 1YK5A 5AI3A 1YUXA 4JADA 3KYXA 1JYBA 1S30A 4ZN3B 4UY81 1RYQA 3PIP1 3PZAA 1VZIA 1WJVA 1R0JA 4AHYA 3KYUA 1Z92B 3A44A 3KYYA 1VZGA 4AHXA 1NNQA 5K2ME 4AI0A 1FHMA 1T9QA 1ZRPA 2ERSA 2KN9A 3LPEB 4AR6A 3NFPI 5MGNA 1BFYA 5AI2A 2AYJA 3RZTA 2PYAA 4JAEA 1R0HA 5GAHc 3WWNB 2A69D 4AR4A 1SMWA 5MFPA 2XJUA 1YUZA 2J9UB 4LHLA 1BQ8A 3PKIA 4WFN1 3IU3I 3PIO1 1IROA 2A6HD 2NYDA 4V196 1LKMA 2DSXA 1LKOA 3KYVA 5DM61 3P2AA 4ZN1B 4AHWA 2JI3A 2O5JD 1NXGA 2C6BA 2KKDA 4AI2A 3KYWA 1NXEA 2CKCA 1LKPA 8RXNA 1B71A 2XJVA 2HR5A 2M4VA 2XJQA 3PWFA 1SMUA 2M4YA 2QL0A 1CADA 1IRNA 4JAFA 2MS3A 2M6PA 3QQCE 7RXNA 5RXNA 2PVXA 4POGA 2PSMC 1RYTA 1B13A 5IY0A 1BE7A 1DVBA 1RDGA 2JI2A 2ERJA 4YWLA 5GADc 1C09A 1RB9A 1VZHA 1DX8A 4XXBB 2CR8A 4RXNA 5MFZA 3B08B 2H12A 5DM71 3RYGA 1R0GA 2ZIXA 2V0FA 4AR3A 2K2DA 5GAGc 4TPUA 1CAAA 3SS2A 1IU6A 4JAGA 3K35A 4E6YA 2JI1A 4YWMA 2Z3RB 6RXNA 1S2ZA 4K9FA 1FHHA 1S24A 2L0ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P2A A;  2PPT A;  2C6A A;  2J9U B;  3B0A B;  2C6B A;  4XXB B;  3B08 B; 
#chains in the Genus database with same CATH topology
 2NVY L;  3PO3 L;  2C6A A;  1LTL A;  3I4N L;  3J7Y 1;  5C44 L;  2Z3Q B;  1IU5 A;  1RWD A;  1YK4 A;  1OWB A;  5MLC 3;  5IYB L;  3ZG6 A;  3LWV B;  3HAX C;  4G6B A;  5MF6 A;  1TWG L;  1BRF A;  3B0A B;  5AN9 H;  5JVG 1;  3I4M L;  1H7V A;  3MPS A;  2RDV A;  4JAD A;  4ZN3 B;  3H9C A;  3H97 A;  1R0J A;  1VZI A;  3S1N L;  5M3F L;  3KYY A;  1TWH L;  5K2M E;  3HJY B;  5IP7 L;  1T9Q A;  4AR6 A;  2KN9 A;  4Y52 L;  3RZT A;  4JAE A;  5FJ8 L;  2AUS B;  2A69 D;  5C3E L;  1SMW A;  2J9U B;  1BQ8 A;  3CQZ L;  4WFN 1;  3KYV A;  3P2A A;  2APO B;  8RXN A;  2M4V A;  4BY7 L;  5C4X L;  2R93 L;  3FKI L;  2PMZ P;  2MS3 A;  3HOV L;  1RDG A;  4YWL A;  1RB9 A;  2CR8 A;  3B08 B;  3S2H L;  1CAA A;  3SS2 A;  1IU6 A;  3H0G L;  3S17 L;  4E6Y A;  4K9F A;  1S24 A;  5EIN C;  2PPT A;  4AR5 A;  2LCQ A;  3S16 L;  3LNL A;  3VPB E;  4QIW P;  4XGH A;  4POF A;  3LWQ B;  3HKZ P;  3QVD A;  3S1R L;  4X6A L;  4ME3 A;  2XJT A;  5H1S c;  3P8B A;  3HOZ L;  1ODH A;  2A6E D;  4A3C L;  2XJS A;  1TWF L;  5IYC L;  4TVM A;  1B2J A;  3RZ6 A;  1QYB A;  1VCX A;  1YK5 A;  3S2D L;  3KYX A;  1TWC L;  3LWO B;  3PIP 1;  1WJV A;  3A44 A;  1VZG A;  1SFO L;  4AI0 A;  5IP9 L;  1FHM A;  2ERS A;  3GTG L;  1R9T L;  1R0H A;  1I3Q L;  5MFP A;  3S1M L;  1YUZ A;  4LHL A;  2NVX L;  2A6H D;  2DSX A;  1LKO A;  3JR7 A;  3HOU L;  1NXG A;  1Y1V L;  2CKC A;  1B71 A;  2E2I L;  1SMU A;  2M4Y A;  5RXN A;  4A3I L;  2M6P A;  3QQC E;  2PVX A;  2NVQ L;  1B13 A;  5IY0 A;  1BE7 A;  1DVB A;  2ERJ A;  4C3H L;  1DX8 A;  1VZH A;  4RXN A;  2H12 A;  1R0G A;  1PZX A;  2ZIX A;  4AR3 A;  2K2D A;  2Y0S P;  4BY1 L;  4C3J L;  6RXN A;  1I6H L;  3PKI A;  3PWF A;  1WCM L;  5IYD L;  1RDV A;  4C2M 1;  4GS7 D;  2GMG A;  2BE5 D;  1BQ9 A;  2XJP A;  4AI3 A;  2NVT L;  1OWC A;  2M6O A;  1IW7 D;  2V3B B;  4A3L L;  2R92 L;  4Y7N L;  2A68 D;  2E2J L;  4A3F L;  1R0F A;  4AHZ A;  2JA7 L;  1T9O A;  2B5I D;  4LHN A;  1PFW A;  1QCV A;  4AI1 A;  3HJW B;  3GTP L;  1YUX A;  1S30 A;  3GTM L;  3LWP B;  3KYU A;  1ZRP A;  3LPE B;  3NFP I;  5AI2 A;  2RFK B;  4AR4 A;  1PFY A;  1PFU A;  3PIO 1;  2NYD A;  4V19 6;  4AHW A;  2YU9 L;  2C6B A;  3PL5 A;  4AI2 A;  1NXE A;  1LKP A;  2XJV A;  2HR5 A;  2XJQ A;  3HOX L;  3HOY L;  2QL0 A;  1CAD A;  4JAF A;  4A3M L;  2PSM C;  1RYT A;  5GAD c;  4XXB B;  5DM7 1;  4BXX L;  3PO2 L;  5GAG c;  3K7A L;  4A3E L;  4C3I L;  4BBR L;  2JI1 A;  4A3G L;  2EY4 E;  1FHH A;  1P7P A;  5EIO C;  4BBS L;  5C4J L;  5JVH 1;  3S14 L;  5GAE c;  3S1Q L;  1PFV A;  1YV1 A;  5M5X L;  1T9P A;  2V0E A;  1SMM A;  2VL6 A;  2CKA A;  1TWA L;  3PKJ A;  5M3M L;  5M5W L;  2XJR A;  2JA8 L;  3M3Y L;  3MSU A;  2WB1 P;  1R0I A;  3RZO L;  4AYB P;  2PVE A;  3RZD L;  3WWL A;  4B8C D;  3J7Z 1;  2R7Z L;  1B2O A;  3FDJ A;  5M5Y L;  1E8J A;  4U67 1;  3GTO L;  3H9B A;  3H3V M;  1K83 L;  2WAQ P;  5AI3 A;  1JYB A;  4UY8 1;  1RYQ A;  3PZA A;  4AHY A;  3S15 L;  1Z92 B;  2JA6 L;  4AHX A;  4A3J L;  1NNQ A;  2HVY C;  1F4L A;  1BFY A;  4A3B L;  5MGN A;  2AYJ A;  3HOW L;  2PYA A;  5GAH c;  3WWN B;  4A93 L;  2XJU A;  2VUM L;  1I50 L;  3IU3 I;  1IRO A;  1LKM A;  5DM6 1;  3M4O L;  1Y1W L;  4ZN1 B;  2JI3 A;  1QQT A;  2O5J D;  2KKD A;  3KYW A;  3GTL L;  3GTQ L;  7RXN A;  1IRN A;  4A3K L;  2AQC A;  5FLM L;  4POG A;  2JI2 A;  3GTK L;  1C09 A;  5MFZ A;  3GTJ L;  3RYG A;  3H99 A;  2V0F A;  4TPU A;  4JAG A;  3K35 A;  3MQK B;  4YWM A;  2JA5 L;  2Z3R B;  1S2Z A;  2B63 L;  4A3D L;  3LWR B;  2E2H L;  2L0Z A; 
#chains in the Genus database with same CATH homology
 5EIO C;  5EIN C;  2PPT A;  5JVH 1;  1RDV A;  5GAE c;  4GS7 D;  1YV1 A;  2GMG A;  4AR5 A;  1T9P A;  2C6A A;  2BE5 D;  2V0E A;  1LTL A;  1SMM A;  2VL6 A;  3LNL A;  1BQ9 A;  2XJP A;  2CKA A;  2LCQ A;  4AI3 A;  3PKJ A;  3VPB E;  4XGH A;  1OWC A;  2M6O A;  3J7Y 1;  2XJR A;  1IW7 D;  2V3B B;  2Z3Q B;  4POF A;  1IU5 A;  1RWD A;  1YK4 A;  2A68 D;  3QVD A;  1OWB A;  5MLC 3;  3MSU A;  1R0F A;  4AHZ A;  1R0I A;  3ZG6 A;  4ME3 A;  2PVE A;  1T9O A;  2XJT A;  5H1S c;  4G6B A;  3P8B A;  2B5I D;  4LHN A;  1QCV A;  3WWL A;  4AI1 A;  4B8C D;  5MF6 A;  3J7Z 1;  1BRF A;  2A6E D;  1B2O A;  1ODH A;  2XJS A;  3B0A B;  5AN9 H;  1E8J A;  4TVM A;  4U67 1;  1B2J A;  3RZ6 A;  5JVG 1;  1QYB A;  1VCX A;  1H7V A;  3MPS A;  2RDV A;  1YK5 A;  5AI3 A;  1YUX A;  4JAD A;  3KYX A;  1JYB A;  1S30 A;  4ZN3 B;  4UY8 1;  1RYQ A;  3PIP 1;  3PZA A;  1VZI A;  1WJV A;  1R0J A;  4AHY A;  3KYU A;  1Z92 B;  3A44 A;  3KYY A;  1VZG A;  4AHX A;  1NNQ A;  5K2M E;  4AI0 A;  1FHM A;  1T9Q A;  1ZRP A;  2ERS A;  2KN9 A;  3LPE B;  4AR6 A;  3NFP I;  5MGN A;  1BFY A;  5AI2 A;  2AYJ A;  3RZT A;  2PYA A;  4JAE A;  1R0H A;  5GAH c;  3WWN B;  2A69 D;  4AR4 A;  1SMW A;  5MFP A;  2XJU A;  1YUZ A;  2J9U B;  4LHL A;  1BQ8 A;  3PKI A;  4WFN 1;  3IU3 I;  3PIO 1;  1IRO A;  2A6H D;  2NYD A;  4V19 6;  1LKM A;  2DSX A;  1LKO A;  3KYV A;  5DM6 1;  3P2A A;  4ZN1 B;  4AHW A;  2JI3 A;  2O5J D;  1NXG A;  2C6B A;  2KKD A;  4AI2 A;  3KYW A;  1NXE A;  2CKC A;  1LKP A;  8RXN A;  1B71 A;  2XJV A;  2HR5 A;  2M4V A;  2XJQ A;  3PWF A;  1SMU A;  2M4Y A;  2QL0 A;  1CAD A;  1IRN A;  4JAF A;  2MS3 A;  2M6P A;  3QQC E;  7RXN A;  5RXN A;  2PVX A;  4POG A;  2PSM C;  1RYT A;  1B13 A;  5IY0 A;  1BE7 A;  1DVB A;  1RDG A;  2JI2 A;  2ERJ A;  4YWL A;  5GAD c;  1C09 A;  1RB9 A;  1VZH A;  1DX8 A;  4XXB B;  2CR8 A;  4RXN A;  5MFZ A;  3B08 B;  2H12 A;  5DM7 1;  3RYG A;  1R0G A;  2ZIX A;  2V0F A;  4AR3 A;  2K2D A;  5GAG c;  4TPU A;  1CAA A;  3SS2 A;  1IU6 A;  4JAG A;  3K35 A;  4E6Y A;  2JI1 A;  4YWM A;  2Z3R B;  6RXN A;  1S2Z A;  4K9F A;  1FHH A;  1S24 A;  2L0Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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