2CKAA

Solution structures of the brk domains of the human chromo helicase domain 7 and 8, reveals structural similarity with gyf domain suggesting a role in protein interaction
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
58
structure length
58
Chain Sequence
LDVDLETRIPVINKVDGTLLVGEDAPRRAELEMWLQGHPEFAVDPRFLAYMEDRRKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 8
total genus 14
structure length 58
sequence length 58
ec nomenclature ec 3.6.4.12: DNA helicase.
pdb deposition date 2006-04-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07533 BRK BRK domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.130 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2ckaA01
2V0EA 2CKAA 2CKCA 2V0FA
chains in the Genus database with same CATH superfamily
1ZRPA 1VZIA 4JAEA 2HVYC 3S2HL 1RDVA 5MFPA 1B13A 3FKIL 4A3CL 5M5WL 1R0IA 3GTGL 2XJQA 1BQ9A 5GAEc 4BBRL 3S1RL 4AHZA 1LTLA 3GTKL 3P2AA 4Y52L 2PVEA 2ZIXA 2XJUA 2V3BB 4TPUA 3CQZL 1T9PA 3RZ6A 2M4YA 1LKOA 2M6PA 3H9CA 1TWGL 4AR6A 3PO3L 1B2JA 1Y1VL 2M6OA 3S1NL 3RZOL 4TVMA 5JVG1 3PWFA 8RXNA 3A44A 1SMWA 2B5ID 1QYBA 4XGHA 5AN9H 1R9TL 2RDVA 4AI0A 4Y7NL 2NYDA 3J7Z1 2XJPA 2BE5D 3HOZL 2V0FA 3JR7A 5GAHc 3S15L 3FDJA 1BRFA 2C6AA 4JAFA 5C4JL 1CAAA 1SMUA 1Z92B 3M4OL 1YUXA 3LPEB 3H97A 4QIWP 2E2JL 3S16L 3LNLA 2AQCA 3J7Y1 4C2M1 1SFOL 5M3FL 1TWFL 1ODHA 3PL5A 4A3KL 4C3HL 1VZHA 2A68D 3HOVL 1R0HA 1LKPA 1R0GA 2J9UB 3H3VM 4YWMA 4ME3A 1FHMA 4A3JL 2KKDA 5DM71 1YV1A 4WFN1 2B63L 3KYVA 5DM61 1OWBA 2R93L 5RXNA 3H0GL 1RB9A 4C3IL 2VL6A 1T9OA 4AHYA 2M4VA 4C3JL 2E2HL 3LWRB 4U671 5EIOC 2YU9L 5M3ML 1NXEA 2NVTL 1BQ8A 1PFWA 2MS3A 3KYUA 1B71A 1PFUA 1BE7A 3PZAA 2JI2A 1JYBA 4AHWA 2WB1P 2R92L 3LWVB 1Y1WL 1QCVA 3KYXA 1LKMA 1I3QL 5M5XL 1T9QA 5IYDL 3K7AL 2H12A 4X6AL 3HJWB 2JI1A 1RWDA 2CR8A 4A3LL 5MLC3 1QQTA 1TWCL 2APOB 2XJRA 2A6HD 3S2DL 4BY7L 4AHXA 3B08B 1YUZA 1DX8A 1NXGA 4AR5A 2ERJA 1S30A 5GADc 1B2OA 1VCXA 3LWPB 3HOUL 3GTML 1OWCA 2XJTA 1IRNA 3B0AB 2AUSB 5C4XL 4A3EL 1I50L 5MGNA 4A3GL 4AI3A 2CKAA 3PIO1 2NVXL 3K35A 5IY0A 4YWLA 1RYTA 1IROA 4AI2A 5EINC 3RZDL 3H9BA 3HJYB 3QVDA 3H99A 3MSUA 3GTLL 2PMZP 3S14L 6RXNA 1TWAL 4RXNA 2KN9A 5GAGc 4AR3A 2Z3QB 3PO2L 2JA6L 5IP9L 4A3IL 4JADA 3LWQB 3KYYA 4E6YA 1PZXA 2JA8L 1CADA 2Y0SP 2CKCA 1BFYA 2A69D 2C6BA 3PKIA 4BBSL 3HOYL 1H7VA 3NFPI 4AR4A 4LHNA 2ERSA 1IU5A 4BY1L 3RZTA 1TWHL 2XJVA 2QL0A 4GS7D 3SS2A 2PSMC 2K2DA 4A3ML 1E8JA 2GMGA 2O5JD 2HR5A 3M3YL 3HAXC 4POGA 3VPBE 5K2ME 1S24A 2WAQP 1IW7D 3S1QL 4ZN1B 3HOXL 5MFZA 4V196 1K83L 2PYAA 4AI1A 1NNQA 5FLML 3HKZP 2RFKB 1PFYA 3WWNB 5AI2A 3GTQL 1RYQA 1IU6A 1F4LA 2PPTA 1P7PA 2AYJA 3I4ML 3MPSA 5AI3A 3HOWL 1I6HL 2V0EA 3KYWA 5IYBL 4XXBB 2EY4E 3GTOL 4POFA 2L0ZA 2DSXA 4B8CD 4JAGA 4AYBP 3S17L 1R0FA 2R7ZL 7RXNA 1YK4A 3WWLA 5H1Sc 4K9FA 3GTJL 2JA7L 3MQKB 5MF6A 4ZN3B 1WJVA 1WCML 2Z3RB 2NVYL 4A3DL 2A6ED 1S2ZA 4A3BL 1PFVA 5C3EL 1SMMA 5M5YL 4A93L 3LWOB 2LCQA 3QQCE 5JVH1 1C09A 1DVBA 3P8BA 5IP7L 4UY81 1VZGA 1YK5A 3I4NL 3S1ML 1R0JA 4BXXL 3GTPL 3PKJA 3ZG6A 4A3FL 2PVXA 4G6BA 1FHHA 4LHLA 2VUML 3PIP1 2NVQL 2JA5L 5IYCL 5FJ8L 1RDGA 2XJSA 5C44L 3IU3I 3RYGA 2JI3A 2E2IL
chains in the Genus database with same CATH topology
1ZRPA 2KKDA 1VZIA 5DM71 1YV1A 3PIO1 3WWNB 4WFN1 4JAEA 5AI2A 1RDVA 3KYVA 5MFPA 3K35A 5IY0A 4YWLA 5DM61 1OWBA 1B13A 1IROA 1RYTA 1RYQA 4AI2A 5EINC 1R0IA 1IU6A 5RXNA 2XJQA 1RB9A 1BQ9A 5GAEc 2PPTA 3QVDA 2AYJA 3MSUA 2VL6A 3MPSA 5AI3A 1LTLA 4AHZA 6RXNA 1T9OA 2V0EA 4AHYA 3KYWA 4RXNA 2KN9A 3P2AA 2M4VA 4XXBB 5GAGc 2PVEA 2ZIXA 4POFA 4AR3A 2L0ZA 2DSXA 2XJUA 4U671 5EIOC 4B8CD 4JAGA 1NXEA 2V3BB 4TPUA 1R0FA 7RXNA 2Z3QB 1T9PA 1YK4A 3WWLA 5H1Sc 1BQ8A 3RZ6A 2MS3A 2M4YA 1LKOA 2M6PA 3KYUA 4K9FA 1B71A 1BE7A 3PZAA 5MF6A 2JI2A 1JYBA 4AR6A 1B2JA 4AHWA 4ZN3B 1WJVA 2M6OA 4JADA 1QCVA 2Z3RB 4TVMA 5JVG1 3PWFA 8RXNA 3KYXA 3KYYA 1LKMA 1SMWA 3A44A 2A6ED 1S2ZA 2B5ID 1QYBA 4E6YA 4XGHA 5AN9H 1CADA 2RDVA 4AI0A 2CKCA 2NYDA 1T9QA 3J7Z1 1BFYA 2A69D 1SMMA 2C6BA 2H12A 2XJPA 3PKIA 2BE5D 1H7VA 3NFPI 4AR4A 2V0FA 4LHNA 2ERSA 5GAHc 1IU5A 2LCQA 3QQCE 1BRFA 2C6AA 3RZTA 2JI1A 4JAFA 5JVH1 2XJVA 1CAAA 1C09A 1SMUA 1Z92B 1RWDA 1YUXA 2CR8A 1DVBA 3LPEB 3P8BA 5MLC3 4UY81 2QL0A 1VZGA 1YK5A 2XJRA 1R0JA 2A6HD 4GS7D 3SS2A 3LNLA 4AHXA 3B08B 2PSMC 1YUZA 3PKJA 2K2DA 1E8JA 1DX8A 1NXGA 3J7Y1 4AR5A 2GMGA 3ZG6A 2O5JD 2PVXA 2HR5A 1ODHA 2ERJA 1S30A 4G6BA 5GADc 1B2OA 1FHHA 1VCXA 3VPBE 5K2ME 1S24A 4POGA 1VZHA 2A68D 4LHLA 1R0HA 1OWCA 1LKPA 1IW7D 2XJTA 1R0GA 3PIP1 1IRNA 3B0AB 2J9UB 1RDGA 4ZN1B 5MGNA 5MFZA 4AI3A 2XJSA 4V196 3IU3I 4YWMA 3RYGA 2PYAA 1FHMA 4ME3A 2CKAA 4AI1A 1NNQA 2JI3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V0E A;  2CKA A;  2CKC A;  2V0F A; 
#chains in the Genus database with same CATH topology
 1ZRP A;  1VZI A;  4JAE A;  2HVY C;  3S2H L;  1RDV A;  5MFP A;  1B13 A;  3FKI L;  4A3C L;  5M5W L;  1R0I A;  3GTG L;  2XJQ A;  1BQ9 A;  5GAE c;  4BBR L;  3S1R L;  4AHZ A;  1LTL A;  3GTK L;  3P2A A;  4Y52 L;  2PVE A;  2ZIX A;  2XJU A;  2V3B B;  4TPU A;  3CQZ L;  1T9P A;  3RZ6 A;  2M4Y A;  1LKO A;  2M6P A;  3H9C A;  1TWG L;  4AR6 A;  3PO3 L;  1B2J A;  1Y1V L;  2M6O A;  3S1N L;  3RZO L;  4TVM A;  5JVG 1;  3PWF A;  8RXN A;  3A44 A;  1SMW A;  2B5I D;  1QYB A;  4XGH A;  5AN9 H;  1R9T L;  2RDV A;  4AI0 A;  4Y7N L;  2NYD A;  3J7Z 1;  2XJP A;  2BE5 D;  3HOZ L;  2V0F A;  3JR7 A;  5GAH c;  3S15 L;  3FDJ A;  1BRF A;  2C6A A;  4JAF A;  5C4J L;  1CAA A;  1SMU A;  1Z92 B;  3M4O L;  1YUX A;  3LPE B;  3H97 A;  4QIW P;  2E2J L;  3S16 L;  3LNL A;  2AQC A;  3J7Y 1;  4C2M 1;  1SFO L;  5M3F L;  1TWF L;  1ODH A;  3PL5 A;  4A3K L;  4C3H L;  1VZH A;  2A68 D;  3HOV L;  1R0H A;  1LKP A;  1R0G A;  2J9U B;  3H3V M;  4YWM A;  4ME3 A;  1FHM A;  4A3J L;  2KKD A;  5DM7 1;  1YV1 A;  4WFN 1;  2B63 L;  3KYV A;  5DM6 1;  1OWB A;  2R93 L;  5RXN A;  3H0G L;  1RB9 A;  4C3I L;  2VL6 A;  1T9O A;  4AHY A;  2M4V A;  4C3J L;  2E2H L;  3LWR B;  4U67 1;  5EIO C;  2YU9 L;  5M3M L;  1NXE A;  2NVT L;  1BQ8 A;  1PFW A;  2MS3 A;  3KYU A;  1B71 A;  1PFU A;  1BE7 A;  3PZA A;  2JI2 A;  1JYB A;  4AHW A;  2WB1 P;  2R92 L;  3LWV B;  1Y1W L;  1QCV A;  3KYX A;  1LKM A;  1I3Q L;  5M5X L;  1T9Q A;  5IYD L;  3K7A L;  2H12 A;  4X6A L;  3HJW B;  2JI1 A;  1RWD A;  2CR8 A;  4A3L L;  5MLC 3;  1QQT A;  1TWC L;  2APO B;  2XJR A;  2A6H D;  3S2D L;  4BY7 L;  4AHX A;  3B08 B;  1YUZ A;  1DX8 A;  1NXG A;  4AR5 A;  2ERJ A;  1S30 A;  5GAD c;  1B2O A;  1VCX A;  3LWP B;  3HOU L;  3GTM L;  1OWC A;  2XJT A;  1IRN A;  3B0A B;  2AUS B;  5C4X L;  4A3E L;  1I50 L;  5MGN A;  4A3G L;  4AI3 A;  2CKA A;  3PIO 1;  2NVX L;  3K35 A;  5IY0 A;  4YWL A;  1RYT A;  1IRO A;  4AI2 A;  5EIN C;  3RZD L;  3H9B A;  3HJY B;  3QVD A;  3H99 A;  3MSU A;  3GTL L;  2PMZ P;  3S14 L;  6RXN A;  1TWA L;  4RXN A;  2KN9 A;  5GAG c;  4AR3 A;  2Z3Q B;  3PO2 L;  2JA6 L;  5IP9 L;  4A3I L;  4JAD A;  3LWQ B;  3KYY A;  4E6Y A;  1PZX A;  2JA8 L;  1CAD A;  2Y0S P;  2CKC A;  1BFY A;  2A69 D;  2C6B A;  3PKI A;  4BBS L;  3HOY L;  1H7V A;  3NFP I;  4AR4 A;  4LHN A;  2ERS A;  1IU5 A;  4BY1 L;  3RZT A;  1TWH L;  2XJV A;  2QL0 A;  4GS7 D;  3SS2 A;  2PSM C;  2K2D A;  4A3M L;  1E8J A;  2GMG A;  2O5J D;  2HR5 A;  3M3Y L;  3HAX C;  4POG A;  3VPB E;  5K2M E;  1S24 A;  2WAQ P;  1IW7 D;  3S1Q L;  4ZN1 B;  3HOX L;  5MFZ A;  4V19 6;  1K83 L;  2PYA A;  4AI1 A;  1NNQ A;  5FLM L;  3HKZ P;  2RFK B;  1PFY A;  3WWN B;  5AI2 A;  3GTQ L;  1RYQ A;  1IU6 A;  1F4L A;  2PPT A;  1P7P A;  2AYJ A;  3I4M L;  3MPS A;  5AI3 A;  3HOW L;  1I6H L;  2V0E A;  3KYW A;  5IYB L;  4XXB B;  2EY4 E;  3GTO L;  4POF A;  2L0Z A;  2DSX A;  4B8C D;  4JAG A;  4AYB P;  3S17 L;  1R0F A;  2R7Z L;  7RXN A;  1YK4 A;  3WWL A;  5H1S c;  4K9F A;  3GTJ L;  2JA7 L;  3MQK B;  5MF6 A;  4ZN3 B;  1WJV A;  1WCM L;  2Z3R B;  2NVY L;  4A3D L;  2A6E D;  1S2Z A;  4A3B L;  1PFV A;  5C3E L;  1SMM A;  5M5Y L;  4A93 L;  3LWO B;  2LCQ A;  3QQC E;  5JVH 1;  1C09 A;  1DVB A;  3P8B A;  5IP7 L;  4UY8 1;  1VZG A;  1YK5 A;  3I4N L;  3S1M L;  1R0J A;  4BXX L;  3GTP L;  3PKJ A;  3ZG6 A;  4A3F L;  2PVX A;  4G6B A;  1FHH A;  4LHL A;  2VUM L;  3PIP 1;  2NVQ L;  2JA5 L;  5IYC L;  5FJ8 L;  1RDG A;  2XJS A;  5C44 L;  3IU3 I;  3RYG A;  2JI3 A;  2E2I L; 
#chains in the Genus database with same CATH homology
 1ZRP A;  2KKD A;  1VZI A;  5DM7 1;  1YV1 A;  3PIO 1;  3WWN B;  4WFN 1;  4JAE A;  5AI2 A;  1RDV A;  3KYV A;  5MFP A;  3K35 A;  5IY0 A;  4YWL A;  5DM6 1;  1OWB A;  1B13 A;  1IRO A;  1RYT A;  1RYQ A;  4AI2 A;  5EIN C;  1R0I A;  1IU6 A;  5RXN A;  2XJQ A;  1RB9 A;  1BQ9 A;  5GAE c;  2PPT A;  3QVD A;  2AYJ A;  3MSU A;  2VL6 A;  3MPS A;  5AI3 A;  1LTL A;  4AHZ A;  6RXN A;  1T9O A;  2V0E A;  4AHY A;  3KYW A;  4RXN A;  2KN9 A;  3P2A A;  2M4V A;  4XXB B;  5GAG c;  2PVE A;  2ZIX A;  4POF A;  4AR3 A;  2L0Z A;  2DSX A;  2XJU A;  4U67 1;  5EIO C;  4B8C D;  4JAG A;  1NXE A;  2V3B B;  4TPU A;  1R0F A;  7RXN A;  2Z3Q B;  1T9P A;  1YK4 A;  3WWL A;  5H1S c;  1BQ8 A;  3RZ6 A;  2MS3 A;  2M4Y A;  1LKO A;  2M6P A;  3KYU A;  4K9F A;  1B71 A;  1BE7 A;  3PZA A;  5MF6 A;  2JI2 A;  1JYB A;  4AR6 A;  1B2J A;  4AHW A;  4ZN3 B;  1WJV A;  2M6O A;  4JAD A;  1QCV A;  2Z3R B;  4TVM A;  5JVG 1;  3PWF A;  8RXN A;  3KYX A;  3KYY A;  1LKM A;  1SMW A;  3A44 A;  2A6E D;  1S2Z A;  2B5I D;  1QYB A;  4E6Y A;  4XGH A;  5AN9 H;  1CAD A;  2RDV A;  4AI0 A;  2CKC A;  2NYD A;  1T9Q A;  3J7Z 1;  1BFY A;  2A69 D;  1SMM A;  2C6B A;  2H12 A;  2XJP A;  3PKI A;  2BE5 D;  1H7V A;  3NFP I;  4AR4 A;  2V0F A;  4LHN A;  2ERS A;  5GAH c;  1IU5 A;  2LCQ A;  3QQC E;  1BRF A;  2C6A A;  3RZT A;  2JI1 A;  4JAF A;  5JVH 1;  2XJV A;  1CAA A;  1C09 A;  1SMU A;  1Z92 B;  1RWD A;  1YUX A;  2CR8 A;  1DVB A;  3LPE B;  3P8B A;  5MLC 3;  4UY8 1;  2QL0 A;  1VZG A;  1YK5 A;  2XJR A;  1R0J A;  2A6H D;  4GS7 D;  3SS2 A;  3LNL A;  4AHX A;  3B08 B;  2PSM C;  1YUZ A;  3PKJ A;  2K2D A;  1E8J A;  1DX8 A;  1NXG A;  3J7Y 1;  4AR5 A;  2GMG A;  3ZG6 A;  2O5J D;  2PVX A;  2HR5 A;  1ODH A;  2ERJ A;  1S30 A;  4G6B A;  5GAD c;  1B2O A;  1FHH A;  1VCX A;  3VPB E;  5K2M E;  1S24 A;  4POG A;  1VZH A;  2A68 D;  4LHL A;  1R0H A;  1OWC A;  1LKP A;  1IW7 D;  2XJT A;  1R0G A;  3PIP 1;  1IRN A;  3B0A B;  2J9U B;  1RDG A;  4ZN1 B;  5MGN A;  5MFZ A;  4AI3 A;  2XJS A;  4V19 6;  3IU3 I;  4YWM A;  3RYG A;  2PYA A;  1FHM A;  4ME3 A;  2CKA A;  4AI1 A;  1NNQ A;  2JI3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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