2CKCA

Solution structures of the brk domains of the human chromo helicase domain 7 and 8, reveals structural similarity with gyf domain suggesting a role in protein interaction
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
60
structure length
60
Chain Sequence
LDPDTRIPVINLEDGTRLVGEDAPKNKDLVEWLKLHPTYTVDMPSYVPKNADVLFSSFQK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7
total genus 9
structure length 60
sequence length 60
ec nomenclature ec 3.6.4.12: DNA helicase.
pdb deposition date 2006-04-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07533 BRK BRK domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.130 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2ckcA00
2V0FA 2CKCA 2V0EA 2CKAA
chains in the Genus database with same CATH superfamily
4A3LL 1TWHL 5JVG1 3S2DL 1R0FA 5MF6A 2HVYC 4A3CL 4AI2A 3HJWB 4BY7L 3K35A 2PVXA 2MS3A 1PFVA 1PFUA 5GADc 2A68D 4G6BA 5AI3A 1PFYA 5RXNA 1S2ZA 5EIOC 2B5ID 3HOYL 1CADA 5GAEc 2KN9A 8RXNA 4AHXA 6RXNA 2CR8A 1B2JA 1H7VA 1QYBA 2NYDA 4AR4A 3S15L 1PFWA 3PL5A 1C09A 3FKIL 3GTJL 2E2JL 4JAEA 4X6AL 4AI0A 1BFYA 3ZG6A 1LKMA 5M5YL 5C4JL 3WWNB 1FHHA 2K2DA 3JR7A 5EINC 3K7AL 2C6AA 4AHZA 1VZIA 1TWAL 1R0IA 5C4XL 3PO3L 4GS7D 4A3BL 2E2IL 1WJVA 2JI3A 2AUSB 3QVDA 2NVYL 3HOZL 1RWDA 4C3IL 3KYYA 2AQCA 1R0HA 5M3ML 3S1NL 3IU3I 3GTLL 4A93L 2JA5L 1FHMA 5IP9L 3PO2L 5H1Sc 4BY1L 5C44L 4ZN3B 2NVTL 3KYVA 2A6HD 2AYJA 1RDGA 1JYBA 5DM71 1VZHA 2EY4E 2Z3RB 3GTOL 2R92L 2M4YA 3H99A 3S17L 5FJ8L 4E6YA 4POGA 3NFPI 3MPSA 4LHLA 2RDVA 2PYAA 1BQ8A 1ZRPA 5M3FL 3H0GL 2V0EA 1IU5A 4WFN1 4B8CD 5IYDL 2APOB 2XJTA 3KYXA 5C3EL 3QQCE 4AI1A 3S1ML 1B13A 2JA7L 3LWVB 3VPBE 2H12A 3S1QL 2J9UB 4AYBP 4AR6A 4Y7NL 2VUML 2JI1A 2CKCA 1NNQA 5GAHc 5AI2A 3P2AA 3I4NL 1IROA 5IYBL 3HOWL 2JI2A 4AI3A 1T9OA 3H97A 2XJPA 2Z3QB 3HKZP 3P8BA 2R93L 5MFZA 4UY81 1SMUA 2M6OA 1IU6A 1S30A 5K2ME 3LWOB 1YK4A 4A3IL 2R7ZL 1R9TL 3GTKL 4A3JL 5DM61 3J7Y1 1QCVA 1Y1WL 1YUXA 1YV1A 1T9QA 1OWBA 3H9CA 1I6HL 4YWMA 4A3DL 3PKJA 2XJQA 2WB1P 2E2HL 2WAQP 3MQKB 2ERSA 3S14L 4C2M1 1DX8A 1YUZA 2BE5D 3GTML 3HOVL 1BE7A 2ZIXA 3WWLA 2QL0A 1BQ9A 3HOXL 2RFKB 3I4ML 1SMMA 2XJRA 1VZGA 1S24A 5M5WL 2PPTA 2NVXL 3KYUA 3RZTA 5IYCL 2PMZP 7RXNA 3GTQL 3PWFA 2NVQL 2A69D 4A3KL 2HR5A 4C3JL 3HOUL 1T9PA 5MFPA 1I50L 3KYWA 5GAGc 4XGHA 2M6PA 1LKPA 3LWPB 2O5JD 1WCML 3PIP1 1F4LA 4A3FL 4QIWP 4POFA 4TVMA 4A3EL 1TWFL 1TWCL 1NXEA 2C6BA 1QQTA 1BRFA 1R0JA 5MLC3 5M5XL 3LWRB 4ME3A 4BBRL 1VCXA 1LTLA 1R0GA 4RXNA 2LCQA 3GTPL 1SFOL 1E8JA 1I3QL 1OWCA 3J7Z1 1LKOA 4LHNA 2XJUA 2PSMC 1IW7D 2GMGA 2JA8L 1K83L 2Y0SP 4JAFA 1B2OA 2B63L 2XJSA 4A3GL 1RDVA 3LNLA 1RYTA 3FDJA 1RB9A 3S16L 3M4OL 1Z92B 4C3HL 3B0AB 3CQZL 2A6ED 4AHWA 2YU9L 2ERJA 1P7PA 3RZOL 2CKAA 3B08B 4XXBB 3A44A 3SS2A 4AR5A 4JAGA 1DVBA 3LWQB 3HAXC 2V0FA 1YK5A 2M4VA 2KKDA 1Y1VL 3S1RL 4BXXL 1NXGA 1ODHA 4BBSL 3H3VM 3HJYB 1B71A 5IP7L 1PZXA 2DSXA 4AR3A 2VL6A 4ZN1B 3PKIA 3LPEB 2JA6L 3RZDL 4AHYA 3M3YL 4V196 2PVEA 4YWLA 3S2HL 3PZAA 3RYGA 3GTGL 5MGNA 2L0ZA 3H9BA 1SMWA 2V3BB 1CAAA 1RYQA 5FLML 3MSUA 4JADA 4K9FA 5JVH1 4Y52L 5AN9H 3RZ6A 1IRNA 2XJVA 1TWGL 5IY0A 3PIO1 4TPUA 4U671 4A3ML
chains in the Genus database with same CATH topology
4LHNA 2XJUA 1RDGA 1JYBA 5JVG1 2PSMC 5DM71 1VZHA 5DM61 3J7Y1 1QCVA 1R0FA 5MF6A 2Z3RB 1IW7D 2GMGA 4AI2A 1YUXA 1YV1A 3K35A 1T9QA 1OWBA 2M4YA 4YWMA 4JAFA 2PVXA 1B2OA 2MS3A 3PKJA 5GADc 2XJSA 2A68D 1RDVA 2XJQA 3LNLA 4E6YA 4POGA 4G6BA 5AI3A 1RYTA 1RB9A 5RXNA 3NFPI 1S2ZA 2ERSA 3MPSA 1Z92B 5EIOC 4LHLA 1DX8A 1YUZA 2B5ID 2RDVA 3B0AB 1CADA 2PYAA 5GAEc 2KN9A 2BE5D 1BQ8A 1ZRPA 8RXNA 4AHXA 6RXNA 1BE7A 2A6ED 2ZIXA 4AHWA 2CR8A 3WWLA 2ERJA 1B2JA 2QL0A 1QYBA 2V0EA 1H7VA 1IU5A 1BQ9A 2NYDA 4AR4A 4WFN1 2CKAA 3B08B 1C09A 4XXBB 3A44A 1SMMA 3SS2A 4B8CD 4JAEA 4AR5A 2XJRA 4JAGA 1VZGA 1DVBA 4AI0A 1BFYA 5MFPA 1S24A 2V0FA 1YK5A 2M4VA 3ZG6A 2XJTA 1LKMA 3KYXA 2KKDA 2PPTA 3QQCE 3KYUA 3RZTA 1NXGA 3WWNB 1ODHA 4AI1A 7RXNA 3PWFA 1FHHA 1B13A 1B71A 2K2DA 2A69D 5EINC 3VPBE 2HR5A 2C6AA 1T9PA 2H12A 2DSXA 1VZIA 4AHZA 2J9UB 2VL6A 1R0IA 3KYWA 3PKIA 4AR3A 4ZN1B 5GAGc 4GS7D 4XGHA 4AR6A 3LPEB 1WJVA 4AHYA 2M6PA 2JI3A 1LKPA 3QVDA 2O5JD 2JI1A 3PIP1 4V196 2PVEA 2CKCA 4YWLA 4POFA 3PZAA 3RYGA 1NNQA 4TVMA 5GAHc 5AI2A 3P2AA 5MGNA 1IROA 2L0ZA 1RWDA 1SMWA 2V3BB 1CAAA 3KYYA 1RYQA 1NXEA 2C6BA 2JI2A 3MSUA 1R0JA 1BRFA 4AI3A 1R0HA 5MLC3 3IU3I 1T9OA 2XJPA 2Z3QB 4ME3A 1FHMA 4JADA 4K9FA 1VCXA 1LTLA 3P8BA 5JVH1 5AN9H 1R0GA 3RZ6A 4RXNA 2LCQA 5H1Sc 1IRNA 5MFZA 2XJVA 5IY0A 1SMUA 2M6OA 4UY81 1IU6A 1E8JA 1S30A 5K2ME 3PIO1 1OWCA 4TPUA 1YK4A 3J7Z1 4ZN3B 4U671 3KYVA 2A6HD 2AYJA 1LKOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V0F A;  2CKC A;  2V0E A;  2CKA A; 
#chains in the Genus database with same CATH topology
 4A3L L;  1TWH L;  5JVG 1;  3S2D L;  1R0F A;  5MF6 A;  2HVY C;  4A3C L;  4AI2 A;  3HJW B;  4BY7 L;  3K35 A;  2PVX A;  2MS3 A;  1PFV A;  1PFU A;  5GAD c;  2A68 D;  4G6B A;  5AI3 A;  1PFY A;  5RXN A;  1S2Z A;  5EIO C;  2B5I D;  3HOY L;  1CAD A;  5GAE c;  2KN9 A;  8RXN A;  4AHX A;  6RXN A;  2CR8 A;  1B2J A;  1H7V A;  1QYB A;  2NYD A;  4AR4 A;  3S15 L;  1PFW A;  3PL5 A;  1C09 A;  3FKI L;  3GTJ L;  2E2J L;  4JAE A;  4X6A L;  4AI0 A;  1BFY A;  3ZG6 A;  1LKM A;  5M5Y L;  5C4J L;  3WWN B;  1FHH A;  2K2D A;  3JR7 A;  5EIN C;  3K7A L;  2C6A A;  4AHZ A;  1VZI A;  1TWA L;  1R0I A;  5C4X L;  3PO3 L;  4GS7 D;  4A3B L;  2E2I L;  1WJV A;  2JI3 A;  2AUS B;  3QVD A;  2NVY L;  3HOZ L;  1RWD A;  4C3I L;  3KYY A;  2AQC A;  1R0H A;  5M3M L;  3S1N L;  3IU3 I;  3GTL L;  4A93 L;  2JA5 L;  1FHM A;  5IP9 L;  3PO2 L;  5H1S c;  4BY1 L;  5C44 L;  4ZN3 B;  2NVT L;  3KYV A;  2A6H D;  2AYJ A;  1RDG A;  1JYB A;  5DM7 1;  1VZH A;  2EY4 E;  2Z3R B;  3GTO L;  2R92 L;  2M4Y A;  3H99 A;  3S17 L;  5FJ8 L;  4E6Y A;  4POG A;  3NFP I;  3MPS A;  4LHL A;  2RDV A;  2PYA A;  1BQ8 A;  1ZRP A;  5M3F L;  3H0G L;  2V0E A;  1IU5 A;  4WFN 1;  4B8C D;  5IYD L;  2APO B;  2XJT A;  3KYX A;  5C3E L;  3QQC E;  4AI1 A;  3S1M L;  1B13 A;  2JA7 L;  3LWV B;  3VPB E;  2H12 A;  3S1Q L;  2J9U B;  4AYB P;  4AR6 A;  4Y7N L;  2VUM L;  2JI1 A;  2CKC A;  1NNQ A;  5GAH c;  5AI2 A;  3P2A A;  3I4N L;  1IRO A;  5IYB L;  3HOW L;  2JI2 A;  4AI3 A;  1T9O A;  3H97 A;  2XJP A;  2Z3Q B;  3HKZ P;  3P8B A;  2R93 L;  5MFZ A;  4UY8 1;  1SMU A;  2M6O A;  1IU6 A;  1S30 A;  5K2M E;  3LWO B;  1YK4 A;  4A3I L;  2R7Z L;  1R9T L;  3GTK L;  4A3J L;  5DM6 1;  3J7Y 1;  1QCV A;  1Y1W L;  1YUX A;  1YV1 A;  1T9Q A;  1OWB A;  3H9C A;  1I6H L;  4YWM A;  4A3D L;  3PKJ A;  2XJQ A;  2WB1 P;  2E2H L;  2WAQ P;  3MQK B;  2ERS A;  3S14 L;  4C2M 1;  1DX8 A;  1YUZ A;  2BE5 D;  3GTM L;  3HOV L;  1BE7 A;  2ZIX A;  3WWL A;  2QL0 A;  1BQ9 A;  3HOX L;  2RFK B;  3I4M L;  1SMM A;  2XJR A;  1VZG A;  1S24 A;  5M5W L;  2PPT A;  2NVX L;  3KYU A;  3RZT A;  5IYC L;  2PMZ P;  7RXN A;  3GTQ L;  3PWF A;  2NVQ L;  2A69 D;  4A3K L;  2HR5 A;  4C3J L;  3HOU L;  1T9P A;  5MFP A;  1I50 L;  3KYW A;  5GAG c;  4XGH A;  2M6P A;  1LKP A;  3LWP B;  2O5J D;  1WCM L;  3PIP 1;  1F4L A;  4A3F L;  4QIW P;  4POF A;  4TVM A;  4A3E L;  1TWF L;  1TWC L;  1NXE A;  2C6B A;  1QQT A;  1BRF A;  1R0J A;  5MLC 3;  5M5X L;  3LWR B;  4ME3 A;  4BBR L;  1VCX A;  1LTL A;  1R0G A;  4RXN A;  2LCQ A;  3GTP L;  1SFO L;  1E8J A;  1I3Q L;  1OWC A;  3J7Z 1;  1LKO A;  4LHN A;  2XJU A;  2PSM C;  1IW7 D;  2GMG A;  2JA8 L;  1K83 L;  2Y0S P;  4JAF A;  1B2O A;  2B63 L;  2XJS A;  4A3G L;  1RDV A;  3LNL A;  1RYT A;  3FDJ A;  1RB9 A;  3S16 L;  3M4O L;  1Z92 B;  4C3H L;  3B0A B;  3CQZ L;  2A6E D;  4AHW A;  2YU9 L;  2ERJ A;  1P7P A;  3RZO L;  2CKA A;  3B08 B;  4XXB B;  3A44 A;  3SS2 A;  4AR5 A;  4JAG A;  1DVB A;  3LWQ B;  3HAX C;  2V0F A;  1YK5 A;  2M4V A;  2KKD A;  1Y1V L;  3S1R L;  4BXX L;  1NXG A;  1ODH A;  4BBS L;  3H3V M;  3HJY B;  1B71 A;  5IP7 L;  1PZX A;  2DSX A;  4AR3 A;  2VL6 A;  4ZN1 B;  3PKI A;  3LPE B;  2JA6 L;  3RZD L;  4AHY A;  3M3Y L;  4V19 6;  2PVE A;  4YWL A;  3S2H L;  3PZA A;  3RYG A;  3GTG L;  5MGN A;  2L0Z A;  3H9B A;  1SMW A;  2V3B B;  1CAA A;  1RYQ A;  5FLM L;  3MSU A;  4JAD A;  4K9F A;  5JVH 1;  4Y52 L;  5AN9 H;  3RZ6 A;  1IRN A;  2XJV A;  1TWG L;  5IY0 A;  3PIO 1;  4TPU A;  4U67 1;  4A3M L; 
#chains in the Genus database with same CATH homology
 4LHN A;  2XJU A;  1RDG A;  1JYB A;  5JVG 1;  2PSM C;  5DM7 1;  1VZH A;  5DM6 1;  3J7Y 1;  1QCV A;  1R0F A;  5MF6 A;  2Z3R B;  1IW7 D;  2GMG A;  4AI2 A;  1YUX A;  1YV1 A;  3K35 A;  1T9Q A;  1OWB A;  2M4Y A;  4YWM A;  4JAF A;  2PVX A;  1B2O A;  2MS3 A;  3PKJ A;  5GAD c;  2XJS A;  2A68 D;  1RDV A;  2XJQ A;  3LNL A;  4E6Y A;  4POG A;  4G6B A;  5AI3 A;  1RYT A;  1RB9 A;  5RXN A;  3NFP I;  1S2Z A;  2ERS A;  3MPS A;  1Z92 B;  5EIO C;  4LHL A;  1DX8 A;  1YUZ A;  2B5I D;  2RDV A;  3B0A B;  1CAD A;  2PYA A;  5GAE c;  2KN9 A;  2BE5 D;  1BQ8 A;  1ZRP A;  8RXN A;  4AHX A;  6RXN A;  1BE7 A;  2A6E D;  2ZIX A;  4AHW A;  2CR8 A;  3WWL A;  2ERJ A;  1B2J A;  2QL0 A;  1QYB A;  2V0E A;  1H7V A;  1IU5 A;  1BQ9 A;  2NYD A;  4AR4 A;  4WFN 1;  2CKA A;  3B08 B;  1C09 A;  4XXB B;  3A44 A;  1SMM A;  3SS2 A;  4B8C D;  4JAE A;  4AR5 A;  2XJR A;  4JAG A;  1VZG A;  1DVB A;  4AI0 A;  1BFY A;  5MFP A;  1S24 A;  2V0F A;  1YK5 A;  2M4V A;  3ZG6 A;  2XJT A;  1LKM A;  3KYX A;  2KKD A;  2PPT A;  3QQC E;  3KYU A;  3RZT A;  1NXG A;  3WWN B;  1ODH A;  4AI1 A;  7RXN A;  3PWF A;  1FHH A;  1B13 A;  1B71 A;  2K2D A;  2A69 D;  5EIN C;  3VPB E;  2HR5 A;  2C6A A;  1T9P A;  2H12 A;  2DSX A;  1VZI A;  4AHZ A;  2J9U B;  2VL6 A;  1R0I A;  3KYW A;  3PKI A;  4AR3 A;  4ZN1 B;  5GAG c;  4GS7 D;  4XGH A;  4AR6 A;  3LPE B;  1WJV A;  4AHY A;  2M6P A;  2JI3 A;  1LKP A;  3QVD A;  2O5J D;  2JI1 A;  3PIP 1;  4V19 6;  2PVE A;  2CKC A;  4YWL A;  4POF A;  3PZA A;  3RYG A;  1NNQ A;  4TVM A;  5GAH c;  5AI2 A;  3P2A A;  5MGN A;  1IRO A;  2L0Z A;  1RWD A;  1SMW A;  2V3B B;  1CAA A;  3KYY A;  1RYQ A;  1NXE A;  2C6B A;  2JI2 A;  3MSU A;  1R0J A;  1BRF A;  4AI3 A;  1R0H A;  5MLC 3;  3IU3 I;  1T9O A;  2XJP A;  2Z3Q B;  4ME3 A;  1FHM A;  4JAD A;  4K9F A;  1VCX A;  1LTL A;  3P8B A;  5JVH 1;  5AN9 H;  1R0G A;  3RZ6 A;  4RXN A;  2LCQ A;  5H1S c;  1IRN A;  5MFZ A;  2XJV A;  5IY0 A;  1SMU A;  2M6O A;  4UY8 1;  1IU6 A;  1E8J A;  1S30 A;  5K2M E;  3PIO 1;  1OWC A;  4TPU A;  1YK4 A;  3J7Z 1;  4ZN3 B;  4U67 1;  3KYV A;  2A6H D;  2AYJ A;  1LKO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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